Abstract

The invention relates to a method for holographic generation of an array of focusing points arranged according to multiple positions of the field of an optical system, which comprises: (S10) detecting images formed by the optical system at a plurality of calibration points arranged according to multiple positions of the field of the optical system; (S20) estimating aberrations introduced by the optical system onto the optical field from the detected images; (S30) applying a phase mask to the optical beam in order to generate a plurality of focusing points arranged according to multiple positions in the field of the optical system; wherein the phase mask is calculated from the estimated aberrations in order to simultaneously compensate for the aberrations at each focusing point. The invention also relates to a holographic generation system which carries out this method.

IPC Classes  ?

• G03H 1/04 - Processes or apparatus for producing holograms
• G03H 1/08 - Synthesising holograms
• G03H 1/22 - Processes or apparatus for obtaining an optical image from holograms
• G02B 21/32 - Micromanipulators structurally combined with microscopes

Abstract

An apparatus for detecting one or more chemicals in a sample, the apparatus including: a scanning unit including a light source configured to scan the sample using a light beam having a linear-shaped illumination; a dispersive element configured to receive light from the sample and disperse the received light spatially in a parallel manner; a spatial light modulator configured to receive the dispersed light and select one or more wavelength bands of the dispersed light; and a detection unit including a one-dimensional array of detectors configured to receive the selected one or more wavelength bands and detect the one or more chemicals in the sample based on the selected one or more wavelength bands, each detector of the array of detectors being a photon detector having a detection surface having a dimension below 50 μm, the dimension being in a direction of the linear-shaped illumination.

IPC Classes  ?

• G01N 3/44 - Investigating hardness or rebound hardness by performing impressions under a steady load by indentors, e.g. sphere, pyramid the indentors being put under a minor load and a subsequent major load, i.e. Rockwell system
• G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
• G01J 3/28 - Investigating the spectrum
• G01J 3/30 - Measuring the intensity of spectral lines directly on the spectrum itself

Abstract

An electrolyte composition which comprises a non-aqueous organic solvent, a conducting electrolyte salt, and at least one additive of formula (I): wherein M is a metal, X is H or -O-R and R is an alkyl and an electrochemical device comprising the electrolyte composition.

IPC Classes  ?

• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

The invention concerns a test cell for an EQCM of an electrochemical system comprising a liquid electrolyte. It comprises: - a cell body (10) comprising an electrolyte cavity (11), a quartz resonator (12) coated with a first working electrode (FW) with an active material to be tested and being configured to provide a signal function of a mass variation of the first working electrode (FW), - a cell basis (20) comprising a connecting terminal (22) receiving the signal from the quartz resonator (12), The test cell (8) also comprises a cell holder (30), comprising: - a second electrolyte cavity connecting with the first electrolyte cavity, - a second working electrode, connected to the quartz resonator through the first and second electrolyte cavity (11), comprising similar material to the active material to be tested, - a counter electrode connected to the quartz resonator through the first and second electrolyte cavities (11).

IPC Classes  ?

• G01N 29/02 - Analysing fluids
• G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
• G01N 29/22 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object Details
• H01M 10/52 - Removing gases inside the secondary cell, e.g. by absorption

Abstract

Method for operando characterization of the chemical composition of a battery cell, comprising the following steps: inserting an optical fiber made of chalcogenide glass through the battery cell, cycling the battery, while cycling the battery, generating an optical signal and transmitting it through the optical fiber, detecting, using an infrared spectrometer, the transmitted optical signal at an output extremity of the optical fiber, recording the detected optical signal over time, locating, using fiber evanescent wave spectroscopy, signature wavelengths for which the optical signal intensity is above a predetermined threshold within the spectrum, associating the located signature wavelengths to at least one predetermined chemical species.

IPC Classes  ?

• G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
• G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
• G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
• G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte

Abstract

22 electrochemical device said electrolyte comprising water, zinc sulphate and urea, its use and an electrochemical device comprising said electrolyte.

IPC Classes  ?

• H01M 10/26 - Selection of materials as electrolytes
• H01M 4/24 - Electrodes for alkaline accumulators
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese

Abstract

The invention relates to a process for electrolysing carbon oxides selected from carbon monoxide and/or carbon dioxide into ethylene by means of an electrolyser comprising a cathode catalyst being a dendritic copper oxide catalyst or a dendritic copper catalyst.

IPC Classes  ?

• C25B 3/03 - Acyclic or carbocyclic hydrocarbons
• C23C 8/10 - Oxidising
• C23C 28/00 - Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of main groups , or by combinations of methods provided for in subclasses and
• C25B 1/23 - Carbon monoxide or syngas
• C25B 3/25 - Reduction
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/061 - Metal or alloy
• C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound
• C25D 3/38 - ElectroplatingBaths therefor from solutions of copper
• C25D 5/50 - After-treatment of electroplated surfaces by heat-treatment

Abstract

The present invention relates to a microfluidic device (100) for use in a system for measuring at least one biomarker, of at least one oocyte, said microfluidic device (100) comprising at least one microfluidic channel (43) configured for a passage of a flow of fluid comprising at least one oocyte, the microfluidic channel (43) comprising a restriction section (50) configured to deform the oocyte in at least a first direction and a second direction perpendicular to a microfluidic channel axis, the first direction being different from the second direction.

IPC Classes  ?

• C12N 5/075 - OocytesOogonia
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
• G01N 33/487 - Physical analysis of biological material of liquid biological material
• G01N 15/14 - Optical investigation techniques, e.g. flow cytometry
• G01N 15/10 - Investigating individual particles

Abstract

The disclosure relates to a gas diffusion electrode—GDE—suitable for carbon dioxide electrolysis, said gas diffusion electrode having a gas diffusion membrane, the gas diffusion electrode further comprising an ink (19) deposited on the gas diffusion membrane; wherein the ink comprises an ion-conducting polymer and copper nanoparticles functionalized with one or more pyridine-containing ligands, wherein the one or more pyridine-containing ligands have an anchoring group comprising one sulphur atom tethered to the copper nanoparticles. The disclosure also relates to a gas-fed flow cell comprising such gas diffusion electrode and to a method for producing such GDE as well to the electrolysis of carbon dioxide using such GDE.

IPC Classes  ?

• C25B 11/032 - Gas diffusion electrodes
• C25B 3/07 - Oxygen containing compounds
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/15 - Flow-through cells
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms
• C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound

Abstract

The present disclosure relates to a method to produce an oxygen evolution reaction electrode catalyst assembly comprising a dendritic nickel foam. The method is remarkable in that it comprises the steps of (a) providing a dendritic nickel foam material; (b) etching the dendritic nickel foam material by placing it in a etch solution being an acidic aqueous solution or an aqueous solution of metal chloride and recovering an etched dendritic nickel foam with nickel dendrites showing a chimney-like structure.

IPC Classes  ?

• C25B 11/00 - ElectrodesManufacture thereof not otherwise provided for
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/031 - Porous electrodes
• C25B 11/061 - Metal or alloy
• C25B 11/089 - Alloys

Abstract

x2299, where x is between 0 and 2, endpoints included.

IPC Classes  ?

• G02F 1/1506 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect based on electrodeposition, e.g. electrolytic deposition of an inorganic material on or close to an electrode
• G02F 1/1516 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect characterised by the electrochromic material, e.g. by the electrodeposited material comprising organic material
• G02F 1/1523 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect characterised by the electrochromic material, e.g. by the electrodeposited material comprising inorganic material
• G02F 1/15 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect

Abstract

The present invention relates to an all-solid-state-battery (ASSB) comprising successively: an anode comprising lithium in the metallic state, at least one solid electrolyte layer comprising a solid electrolyte material, and a cathode composite comprising a cathode active material and a halide solid electrolyte, wherein the all- solid-state-battery is submitted to a pressure comprised from 0.05 MPa to 30 MPa. The invention further pertains to a process of making said ASSB comprising assembling a cell comprising the ASSB and applying a pressure ranging from 0.05 MPa to 30 MPa onto the assembled cell.

IPC Classes  ?

• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/134 - Electrodes based on metals, Si or alloys
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/052 - Li-accumulators
• H01M 10/0562 - Solid materials
• H01M 10/0585 - Construction or manufacture of accumulators having only flat construction elements, i.e. flat positive electrodes, flat negative electrodes and flat separators

Abstract

The disruption of endothelial barrier integrity leading to increased vascular permeability contributes to many pathological processes. In a first cohort of 11 patients having cardiac arrest with vascular leakage, the inventors identified that AREG is 56-fold more expressed than control. During a second prospective clinical study, they confirmed a strong association between the plasma level of AREG and the fluid balance in 77 independent patients hospitalized for a cardiogenic shock. The inventors finally showed a crucial role for this protein in Areg-/- mice, with i) no KO-mice achieving a return of spontaneous circulation (ROSC) vs. 40% in WT mice (n=6 per group, p<0.05) and ii) a beneficial effect of 10 µg recombinant AREG i.v. injection at the time of resuscitation, with 80% injected mice that achieve a ROSC vs 40% in controls (n=6, p<0.05). Finally, using markers of vascular extravasation, they demonstrated that AREG administration was decreasing the level of vascular leakage. The results thus indicate that administering AREG in a patient suffering from vascular permeability would be beneficial. Thus, the present invention relates to the use of amphiregulin (AREG) in methods of treating vascular permeability.

IPC Classes  ?

• A61K 38/19 - CytokinesLymphokinesInterferons
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61P 9/14 - VasoprotectivesAntihaemorrhoidalsDrugs for varicose therapyCapillary stabilisers
• A61P 35/00 - Antineoplastic agents

Abstract

Ischemic heart diseases are leading causes of death and reduced life quality worldwide. Although revascularization strategies significantly reduce mortality after acute myocardial infarction (MI), a large number of patients with MI develop chronic heart failure over time. The inventors previously reported that human recombinant ANGPTL4 counteracts ischemia-induced vascular endothelial growth factor signaling and disruption of endothelial cell junctions thus inhibiting vascular permeability. When administered before MI, the inventors could show that ANGPTL4 leads to protection of the coronary capillary network, reduction of no-reflow and infarct size in mice. The inventors also showed that the therapeutic effects observed with ANGPTL4 in ischemic conditions are not due to the CCD fragments but are brought by the FLD fragment (WO2016/110498). To further test the therapeutic potential of the FLD of ANGPTL4 at the onset of reperfusion, the inventors here used a pig model in a clinically relevant model of acute myocardial infarction which can be easily and safely translated to patient treatment. The inventors demonstrated that local (antegrade) delivery of FLD ANGPTL4 to the infarcted pig heart can target the affected regions in an efficient and clinically relevant manner. A single dose of FLD of ANGPTL4 improved heart function, infarct size, fibrosis, and adverse remodeling parameters 28 days after MI. Short term MI experiments along with complementary murine studies revealed myocardial protection. Thus, a single dose of FLD of ANGPTL4 is capable of reducing ischemia-reperfusion injury and protects against deleterious post-ischemic cardiac remodeling and consecutive ischemic heart failure.

IPC Classes  ?

• A61K 38/18 - Growth factorsGrowth regulators
• A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

An electrolyte composition including at least one sodium salt dissolved in a solvent and a combination of additives, wherein: the solvent includes at least one compound selected from the group consisting of ethylene carbonate, dimethyl carbonate, ethyl methyl carbonate, diethyl carbonate, propylene carbonate, a carboxylate ester such as methyl acetate, ethyl acetate, ethyl propionate and methyl propionate, 4-fluorotoluene, 1,1,2,2-tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether, di-fluoro ethylene carbonate, ethyl difluoroacetate and diglyme, and the combination of additives comprises at least tris(trimethylsilyl)phosphite (TMSPi) and succinonitrile (SN).

IPC Classes  ?

• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/052 - Li-accumulators
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

The disclosure relates to a catalyst suitable for electrochemical reduction reactions of one or more carbon oxides, comprising a nitride-doped multi-metallic material comprising a primary metal being copper and one or more secondary metals selected from silver, gold, platinum, palladium, ruthenium, iridium, osmium, and any mixture thereof, wherein the nitride-doped multi-metallic material comprises, as determined by XRD, copper, copper nitride and copper- Me alloy wherein Me is one of the secondary metals and to a gas diffusion electrode suitable for electrolysis of one or more carbon oxides comprising such a catalyst.

IPC Classes  ?

• C25B 3/03 - Acyclic or carbocyclic hydrocarbons
• C25B 3/07 - Oxygen containing compounds
• C25B 3/25 - Reduction
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/15 - Flow-through cells
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/097 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds comprising two or more noble metals or noble metal alloys

Abstract

The disclosure relates to a process for electrolysing carbon dioxide using a gas-fed flow cell comprising a gas diffusion electrode comprising a metal-based catalyst, wherein the catholyte flow is an acidic catholyte flow comprising one or more alkali metal cations, wherein the gas-fed flow cell comprises a bipolar membrane and wherein the acidic catholyte has a pH of at most 5.5 and the catholyte pH is less than the anolyte pH.

IPC Classes  ?

• C25B 1/23 - Carbon monoxide or syngas
• C25B 3/03 - Acyclic or carbocyclic hydrocarbons
• C25B 3/07 - Oxygen containing compounds
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms
• C25B 11/032 - Gas diffusion electrodes
• C25B 15/08 - Supplying or removing reactants or electrolytesRegeneration of electrolytes

Abstract

The invention relates to a sodium layered oxide of formula I: NaxM1a+i-y-z-nM2b+yM3c+zM4d+nO2, wherein: M1a+, M2b+, M3c+and M4d+ are different transition metal ions or mixtures thereof, x is a number ranging from 0.5 to less than 1; y, z and n are numbers ranging from 0.01 to 0.85; y + z + n is less than 1; a, b, c and d are the respective oxidation number of the transition metal ions M1, M2, M3 and M4, respectively; and the cumulative oxidation state of transition metal ions a*(1-y-z-n)+(b*y)+(c*z)+(d*n) is equal to 4-x; and wherein said sodium layered oxide of formula I is not P2- Na2/3Ni1/4Mn1/2Ti1/6Zn1/12O2, P2-Na2/3Ni1/4Mn1/2Ti1/6Mg1/12O2, or P2-Na2/3Ni1/4Mn1/2Ti1/6Mg1/12O2.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel

Abstract

The present invention relates to a polypeptide X1X2-RK-X3X4-KK-X5X6X7X8X9X10-KR-X11X12 SEQ ID NO: 1 able to bind selectively to cells expressing proteoglycans comprising glycosaminoglycans as heparin or heparan sulfate. The linkage of said polypeptide to an internalization peptide enables the polypeptide to be internalized. The present invention relates to a polypeptide X1X2-RK-X3X4-KK-X5X6X7X8X9X10-KR-X11X12 SEQ ID NO: 1 able to bind selectively to cells expressing proteoglycans comprising glycosaminoglycans as heparin or heparan sulfate. The linkage of said polypeptide to an internalization peptide enables the polypeptide to be internalized. The present invention further relates to a conjugated polypeptide comprising said polypeptide and a biomarker, to a cell penetrating polypeptide comprising said polypeptide, optionally a linker and a cell internalization peptide and a chimeric polypeptide comprising said cell penetrating polypeptide and one or more biological cargos.

IPC Classes  ?

• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

Abstract

The present invention relates to an all-solid-state-battery (ASSB) comprising an anode comprising a first solid electrolyte, a cathode composite comprising a second solid electrolyte, a solid electrolyte chosen from the group consisting in the first and the second solid electrolyte, and at least one buffer layer, in contact with a surface of the solid electrolyte, wherein when the solid electrolyte is the first solid electrolyte, one buffer layer is at the interface of said electrolyte with the cathode, and when the solid electrolyte is the second solid electrolyte, one buffer layer is at the interface of said electrolyte with the anode, wherein the first electrolyte is chosen from a sulphide solid electrolyte and a lithium oxide solid electrolyte, wherein the second electrolyte is a halide solid electrolyte, and wherein the buffer layer has a thickness ranging from 0.5 to less than 10 nm. The invention further pertains to an anode assembly, a cathode assembly and an electrolyte assembly comprising at least one buffer layer. The invention also relates to a process for making an ASSB or an assembly according to the invention wherein the buffer layer is deposited by a vapor deposition based method.

IPC Classes  ?

• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/134 - Electrodes based on metals, Si or alloys
• H01M 4/40 - Alloys based on alkali metals
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 10/0562 - Solid materials

Abstract

The present invention relates to Ni-rich Li-rich positive electrode active material doped with high-valence transition metal ions, such as Mo, exhibiting high capacity and excellent cycling stability.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 10/052 - Li-accumulators
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to Li-rich positive electrode active material comprising a layered structure and a disordered rock-salt structure exhibiting high capacity and excellent cycling stability.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

LEC2 controls the drive current to the light emitting device according to a second light emission control signal.

IPC Classes  ?

• H03K 19/195 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits using specified components using superconductive devices
• G01R 33/035 - Measuring direction or magnitude of magnetic fields or magnetic flux using superconductive devices

Abstract

The invention relates to an apparatus (100) for detecting one or more chemicals in a sample, the apparatus comprising: a scanning unit (104) comprising a light source configured to scan the sample using a light beam (112) having a linear-shaped illumination; a dispersive element (120) configured to receive light from the sample and disperse the received light spatially in a parallel manner; a spatial light modulator (122) configured to receive the dispersed light and select one or more wavelength bands of the dispersed light; and a detection unit (124) comprising a one-dimensional array of detectors configured to receive the selected one or more wavelength bands and detect the one or more chemicals in the sample based on the selected one or more wavelength bands, each detector of the array of detectors being a photon detector having a detection surface having a dimension below 50 pm, the dimension being in a direction of the linear-shaped illumination.

IPC Classes  ?

• G01N 21/65 - Raman scattering
• G01J 3/44 - Raman spectrometryScattering spectrometry

Abstract

An electrochemical cell, includes a positive electrode and a negative electrode arranged face to face in the cell body, and a stack of electrolyte layers interposed between the positive electrode and the negative electrode. The stack of electrolyte layers comprises a first layer of solid electrolyte arranged at one end of the positive electrode, a second layer of solid electrolyte arranged at one end of the negative electrode, a composite powder layer interposed between the first layer and the second layer, the composite powder layer comprising an electrolyte powder and an electroactive material powder serving as a reference electrode for the electrochemical cell.

IPC Classes  ?

• H01M 50/569 - Constructional details of current conducting connections for detecting conditions inside cells or batteries, e.g. details of voltage sensing terminals
• H01M 10/0562 - Solid materials

Abstract

The present invention relates to a pharmaceutical combination comprising (i) firibastat, (ii) a diuretic and (iii) a blocker of the systemic renin-angiotensin system selected from the group consisting of angiotensin I converting enzyme inhibitors (ACEIs) and angiotensin II receptor type 1 (AT1R) antagonists. Said composition is particularly useful for the treatment of hypertension and related diseases and conditions.

IPC Classes  ?

• A61K 31/145 - Amines, e.g. amantadine having sulfur atoms, e.g. thiurams (N—C(S)—S—C(S)—N or N—C(S)—S—S—C(S)—N)Sulfinylamines (—N=SO)Sulfonylamines (—N=SO2)
• A61K 31/549 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
• A61K 38/55 - Protease inhibitors
• A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
• A61K 31/41 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
• A61P 9/12 - Antihypertensives

Abstract

The invention relates to a process for electrolysing carbon oxides selected from carbon monoxide and/or carbon dioxide into ethylene by means of an electrolyser comprising a cathode catalyst being a dendritic copper oxide catalyst or a dendritic copper catalyst.

IPC Classes  ?

• C25B 1/23 - Carbon monoxide or syngas
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 9/77 - Assemblies comprising two or more cells of the filter-press type having diaphragms
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound
• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C25B 1/26 - ChlorineCompounds thereof

Abstract

A device is provided that measures an overall generated heat flow rate released by a battery cell The device comprises an electrical power source for charging and discharging the battery, an internal temperature sensor placed inside the battery, a surface temperature sensor placed on the surface of the battery cell, and an ambient temperature sensor placed in the ambient environment. A device is provided that measures an overall generated heat flow rate released by a battery cell The device comprises an electrical power source for charging and discharging the battery, an internal temperature sensor placed inside the battery, a surface temperature sensor placed on the surface of the battery cell, and an ambient temperature sensor placed in the ambient environment. The device also includes a memory that records the temperatures, and a processor. A device is provided that measures an overall generated heat flow rate released by a battery cell The device comprises an electrical power source for charging and discharging the battery, an internal temperature sensor placed inside the battery, a surface temperature sensor placed on the surface of the battery cell, and an ambient temperature sensor placed in the ambient environment. The device also includes a memory that records the temperatures, and a processor. The processor computes characteristic thermal attributes of the battery cell based on a predetermined thermal equivalent circuit of the battery, using temperatures recorded over a predetermined calibration time period, during which the battery is subjected to current emitted by the electrical power source. A device is provided that measures an overall generated heat flow rate released by a battery cell The device comprises an electrical power source for charging and discharging the battery, an internal temperature sensor placed inside the battery, a surface temperature sensor placed on the surface of the battery cell, and an ambient temperature sensor placed in the ambient environment. The device also includes a memory that records the temperatures, and a processor. The processor computes characteristic thermal attributes of the battery cell based on a predetermined thermal equivalent circuit of the battery, using temperatures recorded over a predetermined calibration time period, during which the battery is subjected to current emitted by the electrical power source. The processor then computes the heat flow rate generated by the battery cell towards its ambient environment from a set of recorded temperatures and the thermal attributes of the battery cell.

IPC Classes  ?

• G01N 25/18 - Investigating or analysing materials by the use of thermal means by investigating thermal conductivity
• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries

Abstract

The invention relates to a method for in-life testing of the formation of the solid electrolyte interface layer of a battery cell, comprising the following steps: sensing the temperature within the battery cell, recording a first set of temperature (T) and/or pressure data related to the temperature variation (ΔT) and/or pressure variation within the battery cell over a first charge of the battery cell, and determining a positive or negative datum relating to the formation of solid electrolyte interface layer of the battery cell according to said first set of temperature and/or pressure data

IPC Classes  ?

• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• G01K 11/3206 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in transmittance, scattering or luminescence in optical fibres at discrete locations in the fibre, e.g. using Bragg scattering
• G01L 11/02 - Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by means not provided for in group or by optical means

Abstract

A method for selecting between a first battery cell and a second battery cells includes sensing a total generated heat flow rate emitted by the first battery cell and the second battery cells. The method further includes recording, for the first and second battery cells, first and second sets of heat flow rate data related to the total generated heat flow rate emitted by the first and second battery cells, respectively, over their first charge. The method further includes comparing the first set of heat flow rate data with the second set of heat flow rate data, and selecting one of the first or second battery cells according to the comparison between the first set of heat flow rate data with the second set of heat flow rate data.

IPC Classes  ?

• G01K 11/3206 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in transmittance, scattering or luminescence in optical fibres at discrete locations in the fibre, e.g. using Bragg scattering
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte

Abstract

The present disclosure relates to a method to produce an oxygen evolution reaction electrode catalyst assembly comprising a dendritic nickel foam. The method is remarkable in that it comprises the steps of (a) providing a dendritic nickel foam material; (b) etching the dendritic nickel foam material by placing it in a etch solution being an acidic aqueous solution or an aqueous solution of metal chloride and recovering an etched dendritic nickel foam with nickel dendrites showing a chimney-like structure.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/031 - Porous electrodes
• C25B 11/042 - Electrodes formed of a single material
• C25B 11/089 - Alloys

Abstract

The disclosure relates to a gas diffusion electrode - GDE - suitable for carbon dioxide electrolysis, said gas diffusion electrode having a gas diffusion membrane, the gas diffusion electrode further comprising an ink (19) deposited on the gas diffusion membrane; wherein the ink comprises an ion-conducting polymer and copper nanoparticles functionalized with one or more pyridine-containing ligands, wherein the one or more pyridine-containing ligands have an anchoring group comprising one sulphur atom tethered to the copper nanoparticles. The disclosure also relates to a gas-fed flow cell comprising such gas diffusion electrode and to a method for producing such GDE as well to the electrolysis of carbon dioxide using such GDE.

IPC Classes  ?

• C25B 3/07 - Oxygen containing compounds
• C25B 3/26 - Reduction of carbon dioxide
• C25B 11/032 - Gas diffusion electrodes
• C25B 11/095 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds at least one of the compounds being organic

Abstract

The present disclosure relates to the field of materials capable of absorbing terahertz and millimetric waves. In particular, the present invention relates to a method for preparing a composite material consisting of a polysiloxane and graphite polymer lattice, as well as the composite material obtained by such a method and the ceramics obtainable from such a composite material.

IPC Classes  ?

• C04B 35/571 - Fine ceramics obtained from polymer precursors
• C04B 35/56 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on carbides

Abstract

Method for operando characterization of the chemical composition of a battery cell (12), comprising the following steps: - inserting an optical fiber (14) made of chalcogenide glass through the battery cell (12), - cycling the battery (12), - while cycling the battery (12), generating an optical signal and transmitting it through the optical fiber (14), - detecting, using an infrared spectrometer (20), the transmitted optical signal at an output extremity (14O) of the optical fiber (14), - recording the detected optical signal over time, - locating, using fiber evanescent wave spectroscopy, signature wavelengths for which the optical signal intensity is above a predetermined threshold within the spectrum, - associating said located signature wavelengths to at least one predetermined chemical species.

IPC Classes  ?

• G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
• G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
• G01N 21/552 - Attenuated total reflection
• G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated

Abstract

The present invention generally relates to the use of a transition metal sulphide compound in a positive electrode for solid state batteries, to a transition metal sulphide compound, to a device or a material incorporating said compound, such as a composite material, an electrode, an electrochemical energy storage cell or a device such as an all-solid-state battery. It further relates to a method to manufacture and/or to use such a compound, material or device and to a process to manufacture said compound, material and/or device.

IPC Classes  ?

• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy

Abstract

The invention relates to an electrolyte composition comprising at least one sodium salt dissolved in a solvent and a combination of additives, wherein: - said solvent comprises at least one compound selected from the group consisting of ethylene carbonate, dimethyl carbonate, ethyl methyl carbonate, diethyl carbonate, propylene carbonate, a carboxylate ester such as methyl acetate, ethyl acetate, ethyl propionate and methyl propionate, 4-fluorotoluene, 1,1,2,2-tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether, di-fluoro ethylene carbonate, ethyl difluoroacetate and diglyme, and - the combination of additives comprises at least tris(trimethylsilyl)phosphite (TMSPi) and succinonitrile (SN). The invention also relates to the use of the said electrolyte composition in a Na-ion battery, and a Na-ion battery comprising the same.

IPC Classes  ?

• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/0568 - Liquid materials characterised by the solutes

Abstract

A compound of formula I: NaxNi0.5-yZnyMn0.5-zTizO2 (I), wherein x is a number ranging from 0.7 and 1.1, y is a number superior to 0 and up to 0.1, and z is a number between 0 and 0.5, batteries incorporating the compound and its use in particular as an positive electrode material for Na-ion batteries and cells and a process to obtain such a compound.

IPC Classes  ?

• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• C01G 53/00 - Compounds of nickel

Abstract

The disclosure relates to an OER electrode catalyst assembly comprising a multi-metallic catalyst and a support with the catalyst being deposited on the support, the catalyst comprising one or more iron oxides, the catalyst assembly is remarkable in that the support comprises dendritic nickel foam. A method for producing such catalyst assembly and a process for generating molecular oxygen by an oxygen evolution reaction using such catalyst assembly are also described.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/031 - Porous electrodes
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/061 - Metal or alloy
• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C25B 11/054 - Electrodes comprising electrocatalysts supported on a carrier
• C25D 3/12 - ElectroplatingBaths therefor from solutions of nickel or cobalt
• C25D 5/00 - Electroplating characterised by the processPretreatment or after-treatment of workpieces
• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds

Abstract

12345678910111212 (SEQ ID N°1) able to bind selectively to cells expressing proteoglycans comprising glycosaminoglycans as heparin or heparan sulfate. The linkage of said polypeptide to an internalization peptide enables the polypeptide to be internalized. The present invention further relates to a conjugated polypeptide comprising said polypeptide and a biomarker, to a cell penetrating polypeptide comprising said polypeptide, optionally a linker and a cell internalization peptide and a chimeric polypeptide comprising said cell penetrating polypeptide and one or more biological cargos.

IPC Classes  ?

• C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• A61K 38/00 - Medicinal preparations containing peptides

Abstract

The present invention relates to an electrolysis device comprising an anode and a cathode, wherein the anode and the cathode each are an electrode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of copper, wherein the surface of the metal deposit is in an oxidized, sulfurated, selenated and/or tellurized form and the metal deposit has a specific surface area greater than or equal to 1 m2/g. The present invention relates also to a method for reducing CO2 into hydrocarbons using an electrolysis device according to the invention. The method according to the invention comprises: a) providing an electrolysis device according to the invention; b) exposing the cathode of said electrolysis device to a CO2-containing aqueous catholyte solution; c) exposing the anode of said electrolysis device to an aqueous anolyte solution; and d) applying an electrical current between the anode and the cathode in order to reduce the carbon dioxide into hydrocarbons.

IPC Classes  ?

• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C25B 3/03 - Acyclic or carbocyclic hydrocarbons
• C25B 3/26 - Reduction of carbon dioxide
• C25B 11/061 - Metal or alloy
• C25B 9/15 - Flow-through cells
• C25B 15/08 - Supplying or removing reactants or electrolytesRegeneration of electrolytes
• C25B 9/65 - Means for supplying currentElectrode connectionsElectric inter-cell connections

Abstract

Disclosed are surface modified electrodes, their process of preparation and their use in the electrolytic reduction of carbon dioxide and/or carbon monoxide, as well as an electrochemical cell including the electrode.

IPC Classes  ?

• C25B 11/031 - Porous electrodes
• C25B 3/03 - Acyclic or carbocyclic hydrocarbons
• C25B 3/07 - Oxygen containing compounds
• C25B 3/26 - Reduction of carbon dioxide
• C25B 11/042 - Electrodes formed of a single material

Abstract

The invention relates to an electrical voltage source (1) comprising - an integrated circuit (2) comprising two input terminals configured to receive an electrical control signal, two output terminals configured to deliver an output voltage (Vs), at least one Josephson junction which is coupled to the input terminals and to the output terminals such that the value of the output voltage (Vs) depends on the frequency of the electrical control signal (6), - a cryogenic module (3), - a microwave generator (4) configured to deliver the electrical control signal (6). The source of electrical voltage (1) comprises an adjustment module (5) configured to adjust the amplitude of the electrical control signal (6) as a function of its frequency according to a predetermined rule. The invention further relates to a method for calibrating such a source.

IPC Classes  ?

• G01R 1/28 - Provision in measuring instruments for reference values, e.g. standard voltage, standard waveform
• G01R 35/00 - Testing or calibrating of apparatus covered by the other groups of this subclass
• G05F 3/02 - Regulating voltage or current
• G05F 3/16 - Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices

Abstract

The present invention relates to a method for CO2 electroreduction to syngas, a mixture of carbon monoxide (CO) and hydrogen (H2), using a cathode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of zinc and of a second metal selected from copper, gold and mixtures thereof, and being preferably copper, said metal deposit comprising at least 1 wt % of one or several phases of an alloy of zinc and of the second metal. The present invention relates to a method for CO2 electroreduction to syngas, a mixture of carbon monoxide (CO) and hydrogen (H2), using a cathode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of zinc and of a second metal selected from copper, gold and mixtures thereof, and being preferably copper, said metal deposit comprising at least 1 wt % of one or several phases of an alloy of zinc and of the second metal. The present invention relates also to an electrode useful for performing this method, a process for preparing such an electrode and an electrolysis device comprising such an electrode.

IPC Classes  ?

• C25B 1/23 - Carbon monoxide or syngas
• C25B 11/031 - Porous electrodes
• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
• C25B 11/054 - Electrodes comprising electrocatalysts supported on a carrier
• C25B 11/061 - Metal or alloy
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded

Abstract

The present invention relates to an electrode comprising a metal deposit of zinc and silver, a process for preparing such an electrode, an electrolysis device comprising such an electrode and a method for CO2 electroreduction to CO using such an electrode as a cathode.

IPC Classes  ?

• C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
• C25B 1/23 - Carbon monoxide or syngas
• C25D 3/56 - ElectroplatingBaths therefor from solutions of alloys
• C25D 3/64 - ElectroplatingBaths therefor from solutions of alloys containing more than 50% by weight of silver

Abstract

A superconducting detection device for detecting a single microwave photon, including: —a quantum system with two energy levels of which the ground state and an excited state are controllable and detectable, the quantum system being designed to allow modulable three-wave interaction; —a buffer resonator arranged to receive an incident single microwave photon; —a highly dissipative auxiliary resonator arranged to discharge a photon; and —a reading device arranged to detect the state of the two-level quantum system; the buffer resonator and the auxiliary resonator are coupled to the quantum system; and the excited state of the quantum system and the photon of the auxiliary resonator are created in response to the reception of the incident photon in the buffer resonator and to the application of parametric pumping to the device. A method for detecting a single microwave photon implemented by a device according to the invention.

IPC Classes  ?

• G01J 1/00 - Photometry, e.g. photographic exposure meter
• G01J 1/44 - Electric circuits

Abstract

The present invention relates to compounds, to compositions comprising the same, to methods for preparing the compounds, and the use of these compounds in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

IPC Classes  ?

• C07C 323/58 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
• A61P 9/12 - Antihypertensives
• A61K 31/10 - SulfidesSulfoxidesSulfones
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]

Abstract

The invention relates to an electrochemical cell (1), comprising a positive electrode (11) and a negative electrode (12) disposed face to face in the cell body (10), and a stack of electrolytic layers (13, 14, 15) interposed between the positive electrode (11) and the negative electrode (12). The stack of electrolytic layers (13, 14, 15) comprises a first solid electrolyte layer (13) disposed at one end of the positive electrode (11), a second solid electrolyte layer (14) disposed at one end of the negative electrode (12), a layer of composite powder (15) interposed between the first (13) and the second layer (14), the layer of composite powder (15) comprising an electrolyte powder and a powder of electroactive material functioning as a reference electrode of the electrochemical cell.

IPC Classes  ?

• H01M 10/04 - Construction or manufacture in general
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 10/0562 - Solid materials
• H01M 10/0585 - Construction or manufacture of accumulators having only flat construction elements, i.e. flat positive electrodes, flat negative electrodes and flat separators
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• G01R 31/00 - Arrangements for testing electric propertiesArrangements for locating electric faultsArrangements for electrical testing characterised by what is being tested not provided for elsewhere

Abstract

The present disclosure relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 25/16 - Anti-Parkinson drugs

Abstract

The present invention relates to a method for treating a cancer having a protein kinase gene fused to a gene coding for a nuclear-envelop protein or a protein interacting with the nuclear envelop in a subject comprising administering to the subject a therapeutically effective of an arsenic compound, an inductor of type 1 IFNs and a tyrosine kinase inhibitor (TKI), as combined preparation. Indeed, inventors have validated the present invention with in vivo and in vitro models. Treatments started in mice with leukemic burden being >3% (up to 90%) hCD45+CD7+ cells in the blood as detected by flow cytometry in individual tested mice. DASA (20mg/Kg, diluted in 80mM citric acid, pH2.1) was delivered using per os administration. ATO (5mg/Kg, diluted in TBS, pH7) and PolyI:PolyC (PIPC, 20mg/Kg diluted in PBS, SIGMA) were injected using intraperitoneal route. The time scale of drug delivery is indicated for every experiment performed. Mice were weighed every day of treatments, in order to ensure they were not losing too much weight and also to adjust the delivered drug doses. DASA+ATO+PIPC treated mice had a significantly prolonged survival compared to the other treatment conditions, showing major differences between results of treatment protocols. ATO combined with IFN-type 1 inducers and inhibitors of TK represents a powerful way for eradication of T-ALL cells that implicate high ABL1 activity and nuclear pore protein lesions.

IPC Classes  ?

• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
• A61K 31/555 - Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
• A61K 33/36 - ArsenicCompounds thereof
• A61K 38/21 - Interferons
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to a pharmaceutical combination comprising (i) firibastat, (ii) a diuretic and (iii) a blocker of the systemic renin-angiotensin system selected from the group consisting of angiotensin I converting enzyme inhibitors (ACEIs) and angiotensin II receptor type 1 (AT1R) antagonists. Said composition is particularly useful for the treatment of hypertension and related diseases and conditions.

IPC Classes  ?

• A61K 31/41 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
• A61K 31/549 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
• A61P 7/10 - Antioedematous agentsDiuretics
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 9/12 - Antihypertensives
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/12 - AerosolsFoams
• A61K 31/185 - AcidsAnhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
• A61K 31/255 - Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
• A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
• A61K 31/403 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
• A61K 31/405 - Indole-alkanecarboxylic acidsDerivatives thereof, e.g. tryptophan, indomethacin
• A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
• A61K 31/4704 - 2-Quinolinones, e.g. carbostyril
• A61K 31/567 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
• A61K 35/74 - Bacteria
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 38/05 - Dipeptides
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

The invention relates to a method for selecting between a first and a second battery cells, wherein it comprises the following steps : - sensing the total generated heat flow rate emitted by a first (10A) and second (10B) battery cells, - recording, for the first (10A) and second (10B) battery cells, first and second sets of heat flow rate data related to the total generated heat flow rate emitted by the first (10A) and second (10B) battery cells, respectively, over their first charge, - comparing the first set of heat flow rate data with the second set of heat flow rate data, and - selecting one of the first (10A) or second (10B) battery cells according to the comparison between the first set of heat flow rate data with the second set of heat flow rate data.

IPC Classes  ?

• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
• H01M 10/44 - Methods for charging or discharging
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

IPC Classes  ?

• C07F 9/58 - Pyridine rings
• C07F 9/30 - Phosphinic acids [R2=P(:O)OH]Thiophosphinic acids
• C07F 9/653 - Five-membered rings
• C07F 9/6539 - Five-membered rings

Abstract

The invention relates to a method for in-life testing of the formation of the solid electrolyte interface layer of a battery cell, comprising the following steps : - sensing the temperature within the battery cell, - recording a first set of temperature (T) and/or pressure data related to the temperature variation (ΔΤ) and/or pressure variation within the battery cell over a first charge of the battery cell, and - determining a positive or negative datum relating to the formation of solid electrolyte interface layer of the battery cell according to said first set of temperature and/or pressure data.

IPC Classes  ?

• H01M 10/052 - Li-accumulators
• H01M 10/0562 - Solid materials
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/44 - Methods for charging or discharging
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte

Abstract

The invention concerns a device (12) for measuring the overall generated heat flow rate released by a battery cell (10), comprising: - an electrical power source for charging and discharging the battery, - an internal temperature sensor (16), placed inside the battery, - a surface temperature sensor (18), placed on the surface of the battery cell - an ambient temperature sensor (14), placed in the ambient environment, - a memory (22) for recording the temperatures, and - a processor (24). The processor (24) computes characteristic thermal attributes of the battery cell (10) based on a predetermined thermal equivalent circuit of the battery (10), using temperatures recorded over a predetermined calibration time period, during which the battery is subjected to current emitted by the electrical power source (20). The processor (22) then computes the heat flow rate generated by the battery cell (10) towards its ambient environment from a set of recorded temperatures and the thermal attributes of the battery cell (10).

IPC Classes  ?

• G01K 7/42 - Circuits effecting compensation of thermal inertiaCircuits for predicting the stationary value of a temperature
• G01K 11/32 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in transmittance, scattering or luminescence in optical fibres
• G01K 15/00 - Testing or calibrating of thermometers
• G01K 17/00 - Measuring quantity of heat
• H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte

Abstract

The invention relates to new compounds that mimic Glycosaminoglycans and are able to control interaction between Glycosaminoglycans with their effector molecules. The compounds of the invention are peptides and are able to prevent or reduce the binding of at least one effector molecule with at least one glycosaminoglycan. The compounds according to the invention can be used as drug, in particular for the stimulation of the neurogenesis and more generally to treat nervous system related pathologies.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides
• A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

Abstract

The present application relates to a proton exchange membrane for fuel cell, said membrane having self-regenerating properties, to cells comprising said membranes, and to the manufacturing method thereof via electrospinning.

IPC Classes  ?

• H01M 50/497 - Ionic conductivity
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms
• H01M 50/426 - Fluorocarbon polymers
• H01M 50/449 - Separators, membranes or diaphragms characterised by the material having a layered structure

Abstract

The invention relates to a method for forming at least one periodic array of cracks of an inorganic micropatterned coating, wherein each crack of said at least one periodic array of cracks extends over the substrate along an axis following a linear direction, each axis of each crack being parallel to the axis of the other cracks. The invention also relates to an inorganic micropatterned coating as defined, said coating being obtainable by the method of the invention. The invention also related to a device comprising an inorganic micropatterned coating of the invention, an ink composition for the production of an inorganic micropatterned coating of the invention and the use of said ink composition for obtaining an inorganic micropatterned coating of the invention.

IPC Classes  ?

• C03C 17/23 - Oxides
• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• C01B 13/36 - Methods for preparing oxides or hydroxides in general by precipitation reactions in solutions
• C09D 7/40 - Additives
• C09D 11/037 - Printing inks characterised by features other than the chemical nature of the binder characterised by the pigment
• C08K 3/22 - OxidesHydroxides of metals
• C08K 3/36 - Silica
• C09D 5/28 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects producedFilling pastes for wrinkle, crackle, orange-peel, or similar decorative effects
• C08K 3/16 - Halogen-containing compounds
• C01B 13/18 - Methods for preparing oxides or hydroxides in general by thermal decomposition of compounds, e.g. of salts or hydroxides
• C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating

Abstract

The present invention relates to a positive electrode active material of the following formula (I): NaxLiyMnl-yO2 (I), where x is a number from 0.8 to 1; y is a number strictly greater than 0 and smaller than or equal to 1/3.

IPC Classes  ?

• C01G 45/12 - Complex oxides containing manganese and at least one other metal element
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy

Abstract

An electrolyte composition includes at least a sodium salt dissolved in at least one solvent and a combination of additives. The solvent is any of ethylene carbonate, dimethyl carbonate, ethyl methyl carbonate, diethyl carbonate, propylene carbonate, ethyl acetate, ethyl propionate, methyl propionate, 4-fluorotoluene, 1,1,2,2-tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether, di-fluoro ethylene carbonate, ethyl difluoroacetate, or mixtures of the foregoing. The combination of additives includes at least sodium difluoro(oxalato)borate (NaODFB) and tris(trimethylsilyl)phosphite (TMSPi).

IPC Classes  ?

• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/1393 - Processes of manufacture of electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

The present invention generally relates to the use of a transition metal sulphide compound in a positive electrode for solid state batteries, to a transition metal sulphide compound, to a device or a material incorporating said compound, such as a composite material, an electrode, an electrochemical energy storage cell or a device such as an all-solid-state battery. It further relates to a method to manufacture and/or to use such a compound, material or device and to a process to manufacture said compound, material and/or device.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 10/052 - Li-accumulators
• H01M 10/0562 - Solid materials
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to the new process of preparation of a Li-rich layered oxide based on Mn and optionally on Ni and/or Co in which F is incorporated within the crystal of the oxide (or “fluorinated oxide”). It also relates to the new fluorinated oxide its use as a component in a cathode of a battery.

IPC Classes  ?

• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• C01G 45/12 - Complex oxides containing manganese and at least one other metal element
• C01G 51/00 - Compounds of cobalt
• C01G 53/00 - Compounds of nickel
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

x0.5-yy0.5-zz2 2 (I), wherein x is a number ranging from 0.7 and 1.1, y is a number superior to 0 and up to 0.1, and z is a number between 0 and 0.5., batteries incorporating the compound and its use in particular as an positive electrode material for Na-ion batteries and cells and a process to obtain such a compound.

IPC Classes  ?

• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• C01G 53/00 - Compounds of nickel
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

The present invention relates to compounds, to compositions comprising the same, to methods for preparing the compounds, and the use of these compounds in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

IPC Classes  ?

• A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
• A61K 33/04 - Sulfur, selenium or telluriumCompounds thereof
• A61K 33/42 - PhosphorusCompounds thereof
• A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61P 9/12 - Antihypertensives
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 27/06 - Antiglaucoma agents or miotics

Abstract

The present invention relates to a battery separator comprising monophasic non- woven hybrid nanofibers, wherein: - said non-woven hybrid nanofibers comprise at least one metal oxide and at least one polymer chosen from the group consisting of fluoropolymers, vinylpolymers, polyethers, and mixtures thereof, and - said non-woven hybrid nanofibers have a diameter ranging from 20 to 1,000 nm.

IPC Classes  ?

• H01M 2/14 - Separators; Membranes; Diaphragms; Spacing elements
• H01M 2/16 - Separators; Membranes; Diaphragms; Spacing elements characterised by the material

Abstract

The present invention relates to surface modified electrodes, their process of preparation and their use in the electrolytic reduction of carbon dioxide and/or carbon monoxide, as well as an electrochemical cell comprising said electrode.

IPC Classes  ?

• C25B 1/00 - Electrolytic production of inorganic compounds or non-metals
• C25B 3/04 - Electrolytic production of organic compounds by reduction
• C25B 11/03 - ElectrodesManufacture thereof not otherwise provided for characterised by shape or form perforated or foraminous
• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material

Abstract

Some embodiments include an electrolyte composition for a battery using sodium ions as electrochemical vector, to the use of such an electrolyte composition as non-aqueous liquid electrolyte in a sodium-ion battery and to a sodium-ion battery comprising such a non-aqueous liquid electrolyte. In some embodiments, the amount of (oxalato)borate ranges from 0.05 to 10 wt. %, relative to the total weight of the electrolyte composition.

IPC Classes  ?

• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The invention concerns a superconducting detection device (1) for detecting a single microwave photon (2), characterised in that the device (1) comprises: - a quantum system (10) with two energy levels of which the ground state and an excited state are controllable and detectable, the quantum system (10) being designed to allow modulable three-wave interaction; - a buffer resonator (12) arranged to receive an incident single microwave photon (2); - a highly dissipative auxiliary resonator (14) arranged to discharge a photon (3); and - reading means arranged to detect the state of the two-level quantum system (10); in which the buffer resonator (12) and the auxiliary resonator (14) are coupled to the quantum system (10); and in which the excited state of the quantum system (10) and the photon of the auxiliary resonator (14) are created in response to the reception of the incident photon in the buffer resonator (12) and to the application of parametric pumping (4) to the device (1). The invention also concerns a method for detecting a single microwave photon implemented by means of a device (1) according to the invention.

IPC Classes  ?

• G06N 10/00 - Quantum computing, i.e. information processing based on quantum-mechanical phenomena

Abstract

22 electroreduction to CO using such an electrode as a cathode.

IPC Classes  ?

• C25B 1/00 - Electrolytic production of inorganic compounds or non-metals
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material
• C25D 3/02 - ElectroplatingBaths therefor from solutions

Abstract

222 ),using a cathode comprisingan electrically conductive support of which at least a part of the surface is covered by a metal deposit of zinc and of a second metal selected from copper, gold and mixtures thereof, and being preferably copper, said metal deposit comprising at least 1 wt% of one or several phases of an alloy of zinc and of the second metal. The present invention relates also to an electrode useful for performing this method, a process for preparing such an electrode and an electrolysis device comprising such an electrode.

IPC Classes  ?

• C25B 1/00 - Electrolytic production of inorganic compounds or non-metals
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material
• C25D 3/02 - ElectroplatingBaths therefor from solutions

Abstract

The present invention relates to an electrolysis device comprising an anode and a cathode, wherein the anode and the cathode each are an electrode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of copper, wherein the surface of the metal deposit is in an oxidized, suIfurated, selenated and/or tellurized form and the metal deposit has a specific surface area greater than or equal to 1 m2222-containing aqueous catholyte solution; c) exposing the anode of said electrolysis device to an aqueous anolyte solution; and d) applying an electrical current between the anode and the cathode in order to reduce the carbon dioxide into hydrocarbons.

IPC Classes  ?

• C25B 3/04 - Electrolytic production of organic compounds by reduction
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/03 - ElectrodesManufacture thereof not otherwise provided for characterised by shape or form perforated or foraminous
• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material
• C25B 9/06 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
• C25D 3/38 - ElectroplatingBaths therefor from solutions of copper
• C25D 5/50 - After-treatment of electroplated surfaces by heat-treatment
• C25D 11/34 - Anodisation of metals or alloys not provided for in groups

Abstract

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

IPC Classes  ?

• C07F 9/572 - Five-membered rings
• C07F 9/653 - Five-membered rings
• C07F 9/6539 - Five-membered rings
• C07F 9/30 - Phosphinic acids [R2=P(:O)OH]Thiophosphinic acids
• C07F 9/32 - Esters thereof
• A61K 31/426 - 1,3-Thiazoles
• A61P 9/00 - Drugs for disorders of the cardiovascular system

Abstract

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

IPC Classes  ?

• C07F 9/30 - Phosphinic acids [R2=P(:O)OH]Thiophosphinic acids
• A61K 31/662 - Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61P 9/12 - Antihypertensives

Abstract

x0.5-yy0.5-zz22 (I), in which: - x varies from 0.9 to 1; - y varies from 0.05 to 0.1; - z varies from 0.1 to 0.3, it being understood that, if z is equal to 0.1 and x is equal to 1, then y is not equal to 0.05.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

−1 and a mesopore size ranging from 2 nm to 50 nm. Further, the use of a material having a high specific surface area for the absorption of pollutants species.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• B01J 20/30 - Processes for preparing, regenerating or reactivating

Abstract

The invention relates to new compounds that mimic Glycosaminoglycans and are able to control interaction between Glycosaminoglycans with their effector molecules. The compounds of the invention are peptides and are able to prevent or reduce the binding of at least one effector molecule with at least one glycosaminoglycan. The compounds according to the invention can be used as drug, in particular for the stimulation of the neurogenesis and more generally to treat nervous system related pathologies.

IPC Classes  ?

• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof

Abstract

The present invention relates to an electrolyte composition comprising at least a sodium salt dissolved in at least one solvent and a combination of additives, wherein: - said solvent is selected from the group consisting of: ethylene carbonate, dimethyl carbonate, ethyl methyl carbonate, diethyl carbonate, propylene carbonate, ethyl acetate, ethyl propionate, methyl propionate, 4-fluorotoluene, 1,1,2,2- tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether, di-fluoro ethylene carbonate, ethyl difluoroacetate, and mixtures thereof; - the combination of additives includes at least sodium difluoro(oxalato)borate (NaODFB) and tris(trimethylsilyl)phosphite (TMSPi).

IPC Classes  ?

• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

A sol-gel method for producing an anti-corrosion coating consisting of at least one layer of an oxide on a metal substrate. A non-aqueous solution of a precursor of the oxide is prepared and deposited on one surface at least of the metal substrate in order to cover said surface at least partially with a film comprising the precursor of the oxide. Hydrolysis-condensation of the precursor of the oxide is carried out by exposing the film to a humid atmosphere in order to form an oxide network in the film. Then, a treatment for stabilizing the film on the surface of the substrate is carried out, followed by a heat treatment of the surface of the metal substrate in order to crystallize the network of oxide and form the anti-corrosion coating.

IPC Classes  ?

• C23C 18/12 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
• C23C 22/00 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals

Abstract

3-xx(2-y)423-zz/2z/2 (I) wherein: □ represents a vacancy; and M represents a transition or a non-transition metal ion. The present invention also relates to a method of preparation of the material of formula (I), its uses as a positive electrode material and a Na-ion cell comprising a positive electrode comprising said material of formula (I).

IPC Classes  ?

• H01M 10/0568 - Liquid materials characterised by the solutes
• C01G 31/00 - Compounds of vanadium
• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 4/04 - Processes of manufacture in general
• H01M 4/13915 - Processes of manufacture of electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx containing halogen atoms, e.g. LiCoOxFy
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 10/05 - Accumulators with non-aqueous electrolyte
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to the new process of preparation of a Li-rich layered oxide based on Mn and optionally on Ni and/or Co in which F is incorporated within the crystal of the oxide (or "fluorinated oxide"). It also relates to the new fluorinated oxide its use as a component in a cathode of a battery.

IPC Classes  ?

• C01G 45/12 - Complex oxides containing manganese and at least one other metal element
• C01G 51/00 - Compounds of cobalt
• C01G 53/00 - Compounds of nickel
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy

Abstract

36166 hydroxycarboxyalkyl groups and alkoxycarbonyl groups of formula - COOR1, wherein R1166 alkyl group, said process comprising contacting in an aerobic aqueous and cell-free reaction medium said hydroxyphenyl compound with a HpaB monooxygenase in presence of (i) a flavin compound selected from FAD, FMN and mixtures thereof, (ii) a HpaC or Fre flavin reductase and (iii) a reducing agent being selected from a NADH compound or a NADPH compound.

IPC Classes  ?

• C12P 7/22 - Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
• C12P 7/24 - Preparation of oxygen-containing organic compounds containing a carbonyl group
• C12P 7/42 - Hydroxy carboxylic acids

Abstract

The present invention relates to an electrolyte composition for a battery using sodium ions as electrochemical vector, to the use of such an electrolyte composition as non-aqueous liquid electrolyte in a sodium-ion battery and to a sodium-ion battery comprising such a non-aqueous liquid electrolyte.

IPC Classes  ?

• H01M 10/05 - Accumulators with non-aqueous electrolyte
• H01M 10/0567 - Liquid materials characterised by the additives

Abstract

The invention relates to a process for manufacturing a porous material comprising the following steps of providing incineration clinkers, providing an aqueous binder solution comprising at least one inorganic binder and/or at least one organic-inorganic hybrid binder, mixing said clinkers with said aqueous binder solution comprising at least one inorganic binder and/or at least one organic-inorganic hybrid binder, setting said mixture obtained by heat treatment and finally recovering the porous material thus manufactured. The manufacturing process thus makes it possible to recycle and upgrade the incineration clinkers by means of the production of a porous material. The process is particularly advantageous since the porous material may in particular be obtained very rapidly and may be used as insulating material or construction material.

IPC Classes  ?

• C04B 26/32 - Compounds having one or more carbon-to-metal or carbon-to-silicon linkages containing silicon
• C04B 28/24 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing alkyl ammonium or alkali metal silicatesCompositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing silica sols

Abstract

The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss of dopaminergic neurons.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

Abstract

The invention relates to a method for producing a material with a large specific surface, comprising a step of atomising a liquid composition based on liquid residues from a chemical extraction of clinker, to a material based on clinker residues, characterised by a large specific surface of between 200 m2.g-1 and 900 m2.g-1 and a mesopore size of between 2 nm and 50 nm, and to the use of said materials for the absorption of contaminating species.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/10 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Abstract

The present invention relates to methods and pharmaceutical compositions for the treatment of myeloproliferative disorders in patients presenting a dysregulation of the JAK2-STAT signalling pathway. Using MPN mouse model and clonogenic methyl-cellulose cultures of patient progenitors, the inventors demonstrate that combining ARS with IFN improves most of the benefits provided by IFN alone during MPN treatment. In particular, the present invention relates to a method of treating a myeloproliferative disorder in a patient presenting a dysregulation of the JAK2-STAT signalling pathway comprising administering to the patient a therapeutically effective combination of an interferon polypeptide and an arsenic compound.

IPC Classes  ?

• A61K 33/36 - ArsenicCompounds thereof
• A61K 38/21 - Interferons

Abstract

The invention relates to a stochastic-type microprocessor. In some embodiments, the microprocessor comprises an elementary stochastic computation module able to receive, as input, two random and independent binary input signals each representing a binary coding of two respective given input probability values, and able to generate, as output, a random binary output signal. a second stochastic clock, able to produce a second clock signal.

IPC Classes  ?

• G06F 7/70 - Methods or arrangements for performing computations using a digital non-denominational number representation, i.e. number representation without radixComputing devices using combinations of denominational and non-denominational quantity representations using stochastic pulse trains, i.e. randomly occurring pulses the average pulse rates of which represent numbers
• G06F 7/58 - Random or pseudo-random number generators

Abstract

The invention relates to a process for the preparation of sodium-based solid compounds, such as sodium-based solid alloys and sodium-based crystalline phases by ball-milling using metallic sodium as starting material. 3, obtained by such a process and to their use, as active material for positive electrode, in a Na-ion battery.

IPC Classes  ?

• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• B22F 9/00 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor
• C22C 1/04 - Making non-ferrous alloys by powder metallurgy
• B22F 9/04 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from solid material, e.g. by crushing, grinding or milling
• C22C 24/00 - Alloys based on an alkali or an alkaline earth metal
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• C01B 25/455 - Phosphates containing halogen
• C01B 25/37 - Phosphates of heavy metals
• H01B 1/02 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of metals or alloys
• C22C 1/10 - Alloys containing non-metals

Abstract

The invention relates to a solid energetic composition comprising at least one oxidizing charge and at least one nanostructured material essentially consisting of boron, said material being in amorphous form and comprising clusters of boron nanoparticles, to the process for preparing same, to a propellant comprising such a solid energetic composition and also to the uses of said composition and of said propellant, in particular in the field of space propulsion, in the motor vehicle field, in particular in airbag inflation systems or any other gas-generating system, including protective gas-generating systems, or in the field of generating high pressures for the manufacture of materials, for example for the manufacture of diamond.

IPC Classes  ?

• C06B 45/00 - Compositions or products which are defined by structure or arrangement of component or product
• C06B 47/10 - Compositions in which the components are separately stored until the moment of burning or explosion, e.g. "Sprengel"-type explosivesSuspensions of solid component in a normally non-explosive liquid phase, including a thickened aqueous phase the components comprising a binary propellant a component containing free boron, an organic borane or a binary compound of boron, except with oxygen
• C06D 5/06 - Generation of pressure gas, e.g. for blasting cartridges, starting cartridges, rockets by reaction of two or more solids

Abstract

The invention relates to a sol-gel method for producing an anti-corrosion coating consisting of at least one layer (31, 32) of an oxide on a metal substrate (10). A non-aqueous solution (1) of a precursor of the oxide is prepared (SI) and deposited (S2) on one surface (11) at least of the metal substrate in order to cover said surface at least partially with a film (20) comprising the precursor of the oxide. Hydrolysis-condensation of the precursor of the oxide is carried out (S3) by exposing the film to a humid atmosphere in order to form an oxide network in the film. Then, a treatment for stabilising the film on the surface of the substrate is carried out (S4), followed by a heat treatment (S5) of the surface of the metal substrate in order to crystallise the network of oxide and form the anti-corrosion coating.

IPC Classes  ?

• C23C 18/12 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material

Abstract

A nanostructured material consisting essentially of boron. The material is in amorphous form and comprising aggregates of boron nanoparticles. A method of preparation thereof and the uses thereof.

IPC Classes  ?

• B01J 21/02 - Boron or aluminiumOxides or hydroxides thereof
• B01J 23/04 - Alkali metals
• B01J 27/10 - Chlorides
• B01J 35/10 - Solids characterised by their surface properties or porosity
• C01B 35/02 - BoronBorides

Abstract

A method for melting a sample comprising at least one salt in a microwave cavity, said cavity being at least formed by an enclosure of which the geometry is suitable for resonance, in a single mode, of a stationary electromagnetic field, defining at least one local extremum of the electric or magnetic field in said cavity, said cavity comprising at least one movable reflective face (8, 9), the position of which can be adjusted in such a way as to modify the geometry of the microwave cavity, said sample being arranged in a hollow insert, said method comprising at least the steps consisting of placing said sample or samples in said insert in such a way as to make the arrangement of said sample correspond with one said extremum, emitting microwaves at the frequency ν0 in said cavity, detecting the power reflected in said cavity and adjusting the position of said or at least one said reflective face and/or the frequency of the microwaves in such a way as to minimise said detected power.

IPC Classes  ?

• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
• H05B 6/80 - Apparatus for specific applications
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

The present invention relates to metabolically stable and non- immunogen analogs completely hydrosolubleat physiological pH, and their use for the prevention or treatment of diseases mediated by G-protein coupled receptor (GPCR), in particular (Central Nervous System) CNS and cardiovascular diseases or disorders, or their use in diagnostic methods.

IPC Classes  ?

• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

Abstract

The invention relates to the use of a reverse-transcriptase inhibitor in the prevention or treatment of a degenerative disease.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12Q 1/25 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving enzymes not classifiable in groups

Abstract

The present invention relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 25/00 - Drugs for disorders of the nervous system

Abstract

The invention relates to a stochastic-type microprocessor. The microprocessor comprises an elementary stochastic computation module (1) able to receive as input two random and independent binary input signals (A, B) each representing a binary coding of two respective given input probability values, and able to generate as output a random binary output signal (C). The elementary module comprises: - a programmable logic unit (2), able to combine two input signals (A, B) to generate an output signal (C); an addressable memory (3), able to store an output probability value coded by an output signal (C) generated by the logic unit (2); - a first stochastic clock (4), able to produce a first clock signal (CLK1); - and a second stochastic clock (5) able to produce a second clock signal (CLK2).

IPC Classes  ?

• G06F 7/70 - Methods or arrangements for performing computations using a digital non-denominational number representation, i.e. number representation without radixComputing devices using combinations of denominational and non-denominational quantity representations using stochastic pulse trains, i.e. randomly occurring pulses the average pulse rates of which represent numbers

Abstract

The present invention relates to a method for preparing a transparent fibrillar collagen matrix capable of being used as a tissue substitute for producing a tissue or an artificial organ, in particular a cornea substitute.

IPC Classes  ?

• A61L 27/24 - Collagen

Abstract

The invention concerns a nanostructured material essentially consisting of boron, said material being in amorphous form and comprising aggregates of boron nanoparticles, the methods for preparing same and the uses thereof.

IPC Classes  ?

• C01B 35/02 - BoronBorides
• B01J 21/00 - Catalysts comprising the elements, oxides or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium or hafnium

Abstract

The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61K 38/18 - Growth factorsGrowth regulators
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 38/49 - UrokinaseTissue plasminogen activator
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

The invention is related to metabolically stable apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin receptor in particular of cardiovascular disease (heart failure, hypertension, pulmonary hypertension, kidney failure) and inappropriate vasopressin secretions (SIADH).

IPC Classes  ?

• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

Abstract

The present invention pertains to a fluoropolymer film comprising at least one fluoropolymer hybrid organic/inorganic composite [polymer (FH)], to a process for the manufacture of said fluoropolymer film and to uses of said fluoropolymer film in various applications, in particular in electrochemical applications.

IPC Classes  ?

• C08J 7/04 - Coating
• C08F 214/18 - Monomers containing fluorine
• C08F 220/20 - Esters of polyhydric alcohols or phenols
• H01M 2/14 - Separators; Membranes; Diaphragms; Spacing elements
• H01M 2/16 - Separators; Membranes; Diaphragms; Spacing elements characterised by the material
• H01M 10/052 - Li-accumulators
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes