A topical composition comprising: from 0.01 to 15% w/v of at least one active agent selected from the group consisting of antifungals and anti-inflammatory actives; from 0.1% to 20% w/v of polar aprotic solvent selected from the group consisting of DMSO, acetone and ethyl acetate; from 0.1% to 20% w/v of polyol selected from glycerol, propylene glycol, sorbitol and mixtures thereof; and from 40% to 90% v/v of lower alkanol selected from the group consisting of ethanol, isopropanol and mixtures thereof.
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/08 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61K 31/57 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
A61K 31/4412 - Non-condensed pyridinesHydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
This invention relates to a device (1), a system and a method for applying a volume of liquid to a treatment surface (6). The device includes a container (3) for containing the liquid, a pump (9) for extracting liquid from the container, an actuator (4) for operating the pump (9), and a collapsible receptacle (5) for accommodating extracted liquid.
This invention relates to a device 1, a system and a method for applying a volume of liquid to a treatment surface 6. The device includes a container 3 for containing the liquid, a pump 9 for extracting liquid from the container, an actuator 4 for operating the pump 9, and a collapsible receptacle 5 for accommodating extracted liquid.
An implement 1 for applying a volume of liquid to a treatment surface can include a support 3 onto which is mounted a receptacle 2, the receptacle defining a reservoir space 4 which receives the liquid. The receptacle includes a wall 6 having a working surface that is used to spread the liquid over the treatment surface. The wall 6 is resiliently deformable so in use the working surface maintains contact with the treatment surface when spreading the liquid. The implement has a specific application in applying a transdermal lotion to the axilla area of the user. A system for transdermal administration of a physiological active agent from a liquid composition and a method of using this system are described.
Described are methods comprising applying a liquid pharmaceutical testosterone composition with an implement comprising a support and a receptacle mounted on the support and defining a reservoir space with an open top to receive the liquid, wherein the receptacle includes a flexible membrane integrally forming a base and a wall, the wall being substantially transverse to the base and having a working surface to spread the liquid over the treatment surface, wherein the base has a continuous surface such that liquid cannot pass through the base, wherein the wall includes an inner portion which extends from the base to an upper end and an outer skirt portion, wherein the inner portion and skirt portion form a double-wall structure, and wherein at least the wall is resiliently deformable so the working surface maintains contact with the treatment surface when spreading the liquid.
A transdermal delivery system comprising a composition comprising a pharmacological agent and a penetration enhancer wherein the penetration enhancer comprises polyethylene glycol (PEG) of average molecular weight no more than 300.
A61K 31/57 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
A61P 15/00 - Drugs for genital or sexual disordersContraceptives
A transdermal delivery system comprising a composition comprising a physiologically active agent and a penetration enhancer wherein the penetration enhancer comprises a combination of (i) an ester of salicylic acid, preferably selected from the C6 to C30 aliphatic ester of salicylic acid and (ii) polyethylene glycol (PEG) of average molecular weight no more than 300.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical preparations and medicated compositions for
topical and transdermal applications, namely solutions,
lotions, creams, gels, sticks, sprays, patches, pads,
ointments, pastes, mousses, and aerosols; topical and
trandsermal medicated skin preparations and pharmaceutical
compositions for spray application to the skin, namely
solutions, lotions, creams, gels, sticks, sprays, patches,
pads, ointments, pastes, mousses and aerosols;
pharmaceutical preparations for transdermal delivery, namely
solutions, lotions, creams, gels, sticks, sprays, pads,
ointments, pastes, mousses and aerosols. Dispensers for medical purposes; spray cans and bottles for
medical use; applicators for sprays, aerosols, semi-viscous
solutions, lotions or gels for medical use; apparatus for
use in application of pharmaceuticals for transdermal
delivery; applicators for spraying or dispensing
pharmaceuticals onto the skin; apparatus to apply
predetermined quantities of semi-viscous solutions, lotion
or gel to the skin for medical purposes; apparatus to apply
metered doses of liquid to the skin for medical purposes.
12.
METHOD AND SYSTEM FOR TRANSDERMAL ADMINISTRATION OF VOLATILE ACTIVE
This invention relates to a method of transdermal administration of a volatile active agent, preferably selected from Nicotine and Selegiline, comprising applying a solution, preferably as a spray, containing the volatile active dissolved in a volatile solvent in a concentration in the range of from 0.5 to 25% by weight to an area of skin without occlusion of the applied solution.
This invention relates to a regulator (6) for regulating flow of a liquid from a dispenser (1) that dispenses the liquid from a container (3) containing the liquid (4). The regulator has an inlet (9) to receive the dispensed liquid and an exit (16) through which the liquid is delivered to the user. The inlet (9) receives the liquid receives the liquid at a first speed and delivers it to the user at a second speed which is substantially less than the first speed. The invention also encompasses a dispenser for dispensing the liquid including such a regulator.
B65D 83/30 - Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of the dispensed content, e.g. funnels or hoods
B05B 1/04 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops in flat form, e.g. fan-like, sheet-like
This invention relates to an implement (1) for applying a volume of liquid to a treatment surface. The implement includes a support means (3) onto which is mounted a receptacle (2), the receptacle defining a reservoir space (4) which receives the liquid. The receptacle includes a wall (6) having a working surface that is used to spread the liquid over the treatment surface. The wall (6) is resiliently deformable so in use the working surface maintains contact with the treatment surface when spreading the liquid. The implement has a specific application in applying a transdermal lotion to the axilla area of the user. The invention also relates to a system for transdermal administration of a physiological active agent from a liquid composition and a method of conducting the same.
A61M 35/00 - Devices for applying media, e.g. remedies, on the human body
A45D 40/00 - Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
A45D 34/04 - Appliances specially adapted for applying liquid, e.g. using roller or ball
B05C 17/00 - Hand tools or apparatus using hand-held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
This invention relates to an applicator (2) for dispensing lotion from a dispensing device (1). The applicator includes a receptacle (13) for receiving a measured volume of lotion dispensed from the dispensing device (1). The Receptacle (13) includes an inner member (12) and an outer member (14) which define a collapsible reservoir space (15). Collapsing of the reservoir space (15) causes the lotion to pass through a passageway formed by apertures (18) in the outer member (14). An outer surface (21) of the outer member (14) provides a spreading surface for spreading the lotion on the treatment surface (20) of a user.
A45D 34/04 - Appliances specially adapted for applying liquid, e.g. using roller or ball
A61M 39/00 - Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
B05C 1/06 - Apparatus in which liquid or other fluent material is applied to the surface of the work by contact with a member carrying the liquid or other fluent material, e.g. a porous member loaded with a liquid to be applied as a coating for applying liquid or other fluent material to work of indefinite length by rubbing contact, e.g. by brushes, by pads
A61M 35/00 - Devices for applying media, e.g. remedies, on the human body
B05C 1/04 - Apparatus in which liquid or other fluent material is applied to the surface of the work by contact with a member carrying the liquid or other fluent material, e.g. a porous member loaded with a liquid to be applied as a coating for applying liquid or other fluent material to work of indefinite length
B05C 1/08 - Apparatus in which liquid or other fluent material is applied to the surface of the work by contact with a member carrying the liquid or other fluent material, e.g. a porous member loaded with a liquid to be applied as a coating for applying liquid or other fluent material to work of indefinite length using a roller
The present invention relates to a method and a system for transdermal delivery of a physiologically active agent. The invention further relates to a method of treatment using the transdermal delivery system and the use of medicaments (5) from manufacture of such as system.
Dispensers for medical purposes; bottles for medical use; applicators for semi-viscous solutions, lotions for gels for medical use; apparatus for use in application of pharmaceuticals for transdermal delivery; applicators for dispensing pharmaceuticals onto the skin; apparatus to apply predetermined quantities of semi-viscous lotions or gels to the skin for medical purposes.
Aerosol dispensers for medical purposes; spray cans and bottles for medical use; applicators for sprays and aerosols for medical use; apparatus for use in application of pharmaceuticals for transdermal delivery; applicators for spraying pharmaceuticals onto the skin; apparatus to apply metered doses of liquid to the skin for medical purposes.
