The present invention relates to the technical field of the preparation of plant extracts, and in particular to a method for extracting rutin. The method for extracting rutin involves extracting rutin by means of using Sophorae flos decoction pieces as a raw material, and comprises the step of mixing Sophorae flos decoction pieces with an extraction solvent for extraction, wherein the Sophorae flos decoction pieces are prepared by means of a method comprising the steps of: curing Sophorae flos, fermenting same, and then performing a cracking treatment to make cracks between petals of the Sophorae flos, wherein the mass proportion of fine powder obtained by means of passing the Sophorae flos decoction pieces through a 40-mesh sieve is not more than 25%. Compared with the traditional processing technology for Sophorae flos, the method for preparing Sophorae flos decoction pieces can effectively reduce the loss of rutin, and can significantly improve the leaching efficiency of rutin and reduce the leaching of impurity components such as polysaccharides. By means of the method for extracting rutin, the efficient extraction of rutin from Sophorae flos can be achieved, and the dissolution of impurity components during extraction can also be reduced, so that green and efficient industrial production of Sophorae flos-derived rutin can be achieved.
The present invention relates to the technical field of plant processing, and in particular to a Sophorae flos decoction piece, and a preparation method therefor and the use thereof. The method for preparing the Sophorae flos decoction piece comprises: curing Sophorae flos, fermenting same, and then performing a cracking treatment to make cracks between petals of the Sophorae flos, wherein the mass proportion of fine powder obtained by means of passing the Sophorae flos decoction piece through a 40-mesh sieve is not more than 25%. Compared with the traditional processing technology for Sophorae flos, the method can effectively reduce the loss of rutin and achieve the retention of rutin in Sophorae flos to a greater extent. Moreover, in the use for the purpose of obtaining rutin, the Sophorae flos decoction piece prepared by the method can achieve complete leaching of rutin components while retaining macromolecular components such as polysaccharides in Sophorae flos residues to a greater extent, so that the use value of material residues obtained thereby is maximized, the comprehensive output and added value of Sophorae flos resources are improved, and an effective method for the deep processing of Sophorae flos is provided. The method also has the advantages of a simple and feasible process, etc., and is suitable for industrial application.
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A high-stability oil composition including an oil and quercetagetin. Quercetagetin, as a stabilizer, can delay an oxidation process of the oil and ensure the stability of the oil. The content of the quercetagetin may be more than 1 ppm, preferably more than 5 ppm, more than 10 ppm; preferably more than 20 ppm, more than 30 ppm, more than 40 ppm, more than 50 ppm, more than 60 ppm, more than 70 ppm, more than 80 ppm, more than 90 ppm, preferably more than 100 ppm, more than 200 ppm, more than 300 ppm, more than 400 ppm, more than 500 ppm, more than 600 ppm, more than 700 ppm, more than 800 ppm, more than 900 ppm; preferably more than 1000 ppm, more than 2000 ppm, more than 3000 ppm, more than 4000 ppm, more than 5000 ppm.
Disclosed is an industrial extraction method of cannabidiol, pertaining to the field of medicine and chemical industry. The present invention aims to resolve the problems of difficulty in wax removal, low extraction rate of cannabidiol, and excessively high content of tetrahydrocannabinol during extraction using conventional solvents in the prior art. The extraction method employs raw material pretreatment, granulation, extraction, liquid-liquid extraction, decolorization, concentration, and other processes, such that wax removal from an extracted liquid is improved, the purity of a crude cannabidiol oil can be increased to 60%, and 40% of tetrahydrocannabinol can be removed. The method has high extraction yields and low costs, and can be implemented in large-scale industrial production.
C07C 37/82 - SeparationPurificationStabilisationUse of additives by physical treatment by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by physical treatment by chemisorption
A composition contains quercetagetin and 6-hydroxykaempferol, and, optionally further includes patuletin. The composition has an excellent antioxidant effect, and can be used as an active additive in food, drugs, health care products, cosmetics, and feed. In addition, the composition can prompt animal growth, reduce ratio of feed to gain, and improve meat quality in the feed.
An industrial method for continuously extracting a high-content marigold flavonoid and a marigold flavonoid product obtained thereby. The method comprises the following steps: 1) granulating a marigold flower raw material, a ring mold compression ratio of a granulator being 1:(1.2-2.2); 2) performing extraction on marigold flower particles by using 70-100% acetone as an extracting agent, and filtering same to obtain an extract; and 3) down-regulating the volume fraction of acetone to 0-30%, performing filtering to obtain a filter cake, and drying the filter cake to obtain a marigold flavonoid product. The method is simple, high in continuity and operability, high in productivity, and less in energy consumption, and is thus suitable for industrial production.
A61P 39/06 - Free radical scavengers or antioxidants
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 311/40 - Separation, e.g. from natural materialPurification
A61K 133/00 - Containing or obtained from flowers or blossoms
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Colorants for liqueurs; malt colorants; malt caramel for use as a food colorant; caramel for use as a food colorant; colorants for beer; colorants for butter; food colorants; food dyes; colorants for beverages; natural resins, raw Collyrium; solutions for contact lenses; dietetic foods adapted for medical purposes; food for babies; dietetic beverages adapted for medical purposes; dietetic infusions adapted for medical use; nutritional supplements; protein dietary supplements; dietary supplements for animals; medicated animal feed Yolk of eggs; eggs; butter; cream for butter; cream being dairy products; cheese; milk; edible fats; fruit jelly spreads; jellies for food Sugar; biscuits; custard; cheeseburger sandwiches; cake dough; noodles; seasonings; condiments, namely, pepper sauce; aromatic preparations for food, namely, curry pastes; essences for foodstuffs, except etheric essences and essential oils, namely, extracts used as food flavoring
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Colorants for beverages; food dyes; food colorants; colorants for butter; colorants for beer; malt colorants; caramel for use as a food colorant; malt caramel for use as a food colorant Protein dietary supplements; lecithin dietary supplements; enzyme dietary supplements; nutritional supplements; dietetic infusions adapted for medical use; dietetic beverages adapted for medical purposes; food for babies; dietetic foods adapted for medical purposes; medicated animal feed; dietary supplements for animals
Disclosed is an industrial extraction method of cannabidiol, pertaining to the field of medicine and chemical industry. The present invention aims to resolve the problems of difficulty in wax removal, low extraction rate of cannabidiol, and excessively high content of tetrahydrocannabinol during extraction using conventional solvents in the prior art. The extraction method employs raw material pretreatment, granulation, extraction, liquid-liquid extraction, decolorization, concentration, and other processes, such that wax removal from an extracted liquid is improved, the purity of a crude cannabidiol oil can be increased to 60%, and 40% of tetrahydrocannabinol can be removed. The method has high extraction yields and low costs, and can be implemented in large-scale industrial production.
Disclosed is a quercetagetin-containing feed. The feed has the effects of promoting animal growth, improving animal meat quality, improving animal immunity, improving animal blood-related indicators, improving the antioxidant capacity in an animal body, and improving animal intestinal health. Furthermore, the feed is resistant to deterioration and has a high stability.
A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
A high-stability grease composition, containing grease and quercetagetin. The quercetagetin, as a stabilizer, can delay an oxidation process of grease and ensure the stability of grease.
A composition comprising quercetagetin, comprising quercetagetin and 6-hydroxykaempferol, and further comprising queretagetin. The composition has an excellent antioxidant effect, and can be used as an active additive in food, drugs, health care products, cosmetics, and feed. In addition, the composition can prompt animal growth, reduce feed conversion ratio, and improve meat quality in the feed.
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Disclosed is an industrial method for simultaneously preparing Stevia rebaudiana chlorogenic acid and stevioside. The industrial method includes carrying out alcohol extraction on Stevia rebaudiana which is used as a raw material, and then adjusting the feed liquid state to allow chlorogenic acid to be in a free molecular state; carrying out extraction separation by a water-insoluble moderate-polarity organic solvent; enriching the Stevia rebaudiana chlorogenic acid in an organic layer; and enriching the stevioside in a water layer. Compared with a traditional water extraction process, the method has the advantages that chlorogenic acid ingredient in the Stevia rebaudiana can be prevented from being hydrolyzed, such that the contents and effects of effective ingredients in Stevia rebaudiana chlorogenic acid products can be guaranteed; effective separation can be carried out on the premise that the quality and the production efficiency of stevioside products are unaffected, the production efficiency can be improved, and the ratio of isochlorogenic acid to total chlorogenic acid in the resulting products is close to that in the raw material; production water consumption can be reduced, and discharge of sewage and flocculation residues can be decreased; and accordingly, the method is a green production process with high benefits.
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
Stevia rebaudiana resources, reduces the resource consumption in a production process, reduces waste discharge, and is a high-benefit green production process.
C07H 15/24 - Condensed ring systems having three or more rings
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
17.
HIGH-QUALITY CURCUMIN PRODUCT, PRODUCTION METHOD THEREFOR AND APPLICATION THEREOF
Provided are a high-quality curcumin product, a production method therefor and an application thereof. The high-quality curcumin product has low solvent residue, good fluidity, and a high bulk density. The method for producing the product comprises the following steps: using a turmeric extract as a raw material, adding a certain proportion of a crystallization agent, dissolving at high temperature, then continuing heating or refluxing, cooling and crystallization, and then centrifuging or filtering to obtain crude curcumin, and further drying to obtain high-quality curcumin. The high-quality curcumin can be used as an additive for food, medicine, feed, cosmetics, etc.
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
A23L 5/43 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
Disclosed is an industrializable method for leaching xanthophyll and quercetagetin from particles of marigold flowers. The method comprises the following steps: 1) leaching particles of marigold flowers with a solution of acetone having a volume fraction of 90-99% so as to obtain a leachate; and 2) concentrating the leachate to achieve a solid content of 60-95%, and performing extracting on the resulting concentrate using a low-polarity solvent so as to obtain a quercetagetin product and a xanthophyll product. In the present invention, use of acetone as a leaching solvent to leach particles of marigold flowers enables simultaneous leaching of xanthophyll and quercetagetin, and by carefully controlling the concentration of acetone, the yield of the two products can be increased. In addition, by controlling the degree of concentration, the two effective ingredients can be efficiently isolated, affording high yields of quercetagetin and xanthophyll with high purity.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 311/40 - Separation, e.g. from natural materialPurification
19.
INDUSTRIALIZABLE METHOD FOR RAPIDLY AND EFFICIENTLY EXTRACTING XANTHOPHYLL AND QUERCETAGETIN
Disclosed is an industrializable method for rapidly and efficiently extracting xanthophyll and quercetagetin, comprising the following steps: 1) extracting particles of marigold flower with a solution of acetone having a volume fraction of 90-100% to obtain an extraction solution; and 2) mixing water and the extraction solution at a volume ratio of 1:0.5-25, and then extracting with added n-hexane to obtain a xanthophyll product and a quercetagetin product. Extraction of particles of marigold flower with an acetone solution allows selective and sufficient extraction of xanthophyll and quercetagetin, and addition of water followed by liquid-liquid extraction with n-hexane facilitates separation to obtain the two products. During the whole process, the concentration of acetone and the amount of water added for the separation are strictly controlled to achieve sufficient extraction and better refinement of xanthophyll and quercetagetin, affording an n-hexane phase containing xanthophyll and an acetone phase containing quercetagetin.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 311/40 - Separation, e.g. from natural materialPurification
20.
INDUSTRIALIZED METHOD FOR RAPIDLY AND EFFICIENTLY EXTRACTING XANTHOPHYLL AND QUERCETAGETIN
The present invention relates to the field of natural product extraction, and in particular relates to an industrialized method for rapidly and efficiently extracting xanthophyll and quercetagetin. The main improvement of the method lies in that a mixed solution of n-hexane and acetone solution is used as an extracting agent to extract marigold flower particles, wherein the volume fraction of acetone in the acetone solution is 80%-100%. The mixed extracting agent of the present invention has very high selectivity with regard to xanthophyll and quercetagetin, and can be used for effectively extracting the two effective components, and subsequently, xanthophyll and high-purity quercetagetin products can be obtained through simple separation; and the industrialized method has a simple process, is low in production cost, and is conducive to industrialized production.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 311/40 - Separation, e.g. from natural materialPurification
21.
Method for preparing lycopene crystals with high purity and low harm
The present invention relates to a method for preparing lycopene crystals with high purity and low harm. The method comprises the following steps: (1) mixing lycopene oleoresin with a mixed solvent consisting of an alkane and a lower alcohol, and heating and stirring the resultant for dissolution to form a homogenous solution; (2) cooling the homogenous solution for crystallization, filtering the resultant to obtain a filter cake; and (3) washing the filter cake successively using a lower alcohol and an alkane, and drying the resultant to obtain lycopene crystals. According to the method provided by the present invention, lycopene crystals can be obtained using a mixed solvent by means of one step crystallization, and the crystal content is further improved and harmful substances in the crystals are reduced by means of a two-step crystal washing process to obtain lycopene crystals with high purity and low harm. The method is fast and convenient, lycopene crystals with high purity, low harm, and sanitary safety can be produced, and the method is suitable for industrial production.
Disclosed is a lycopene food colorant having a fresh-keeping function. The food colorant is prepared from the following raw materials in parts by weight: 1-3 parts of a lycopene crystal, 5-20 parts of an emulsifier, 0.5-5 parts of an antioxidant, 60-70 parts of glycerol, and 10-20 parts of water. The food colorant is prepared by mixing the raw materials and then emulsifying and grinding same. The granularity of the obtained lycopene colorant is moderate; the tone is suitable for coloring a minced fillet product; the lycopene colorant has high tinting strength, achieves a bright color, and has the effect of triggering myoglobin, so that the minced fillet product has a bright color and appears fresher; the lycopene colorant further has a fresh-keeping function and can kill some food microorganisms, so as to keep food fresh and prolong the shelf life.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A23L 5/44 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
C09B 61/00 - Dyes of natural origin prepared from natural sources
C09B 67/10 - Influencing the physical properties by treatment with a liquid, e.g. solvents
23.
Pretreatment method for producing lycopene raw material
A pretreatment method for producing a raw material of lycopene, comprising: uniformly mixing tomato peel residue with a fermenting agent, an antioxidant and an enzyme preparation, and subjecting the resultant to light-proof anaerobic fermentation. The present invention employs bacteria-enzyme-combined fermentation technology, which prolongs the storage period of wet tomato peel residue, and also destroys the cell wall of tomato peels, thus facilitating exaction of lycopene and improving the purity of lycopene extracted in the later stage.
The present invention discloses a method for preparing a lycopene micro-capsule powder, wherein lycopene is fully mixed with an aqueous phase to obtain a lycopene emulsion, and the emulsion is then ground to a particle size less than 1 μm, and spray dried. The aqueous phase comprises: a gelatin enzymatic hydrolysate with a molecular weight of 5,000-10,000 Da, disaccharide, polysaccharide, and an antioxidant. The disaccharide is one or more of sucrose, maltose and lactose; and the polysaccharide is one or more of pullulan and chitosan.
A continuous distillation process comprises the following steps: putting a material into a multilayer distillation tower to enable the material to sequentially undergo preheating, extrusion pricking, steam distillation, meal roasting, drying and cooling treatment, condensing essential oil-containing steam, and carrying out water separation, so as to obtain an essential oil.
Disclosed is a method for extracting a marigold flavonoid. The main steps thereof comprise: extracting marigold flower meal by using a methanol solution, concentrating the extracted solution to a solid content of 5%-30%, and filtering same to obtain a supernatant and a filter cake, and drying the filter cake, thus obtaining the marigold flavonoid.
The present invention relates to an industrial preparation method of lutein and marigold flavone. Main improvement points thereof are: mixing a petroleum ether and a flavone extraction solvent; extracting marigold particles; adding a strong-polarity solvent to the flavone extraction solvent after extraction is finished; and further promoting separation of the lutein and the marigold flavone. The present invention uses a double-solvent extraction method, so that the extraction efficiency is improve; the purity of the marigold flavone is improved; furthermore, the method in the present invention is simple in steps and low in costs, and is applicable to industrial large-scale production; the purity of the extracted marigold flavone is high; and the marigold flavone has various bioactivities and has a wide application prospect.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
28.
INDUSTRIAL METHOD FOR SIMULTANEOUSLY PREPARING STEVIA REBAUDIANA CHLOROGENIC ACID AND STEVIOSIDE
Disclosed is an industrial method for simultaneously preparing stevia rebaudiana chlorogenic acid and stevioside. The industrial method includes carrying out alcohol extraction on stevia rebaudiana which is used as a raw material, and then adjusting the feed liquid state to allow chlorogenic acid to be in a free molecular state; carrying out extraction separation by a water-insoluble moderate-polarity organic solvent; enriching the stevia rebaudiana chlorogenic acid in an organic layer; and enriching the stevioside in a water layer. Compared with a traditional water extraction process, the method has the advantages that chlorogenic acid ingredient in the stevia rebaudiana can be prevented from being hydrolyzed, such that the contents and effects of effective ingredients in stevia rebaudiana chlorogenic acid products can be guaranteed; effective separation can be carried out on the premise that the quality and the production efficiency of stevioside products are unaffected, the production efficiency can be improved, and the proportion of isochlorogenic acid in the resulting products is close to the proportion of isochlorogenic acid in the raw material; production water consumption can be reduced, and discharge of sewage and flocculation residues can be decreased; and accordingly, the method is a green production process with high benefits.
C07H 1/08 - SeparationPurification from natural products
C07C 69/732 - Esters of carboxylic acids having esterified carboxyl groups bound to acyclic carbon atoms and having any of the groups OH, O-metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
C07C 67/48 - SeparationPurificationStabilisationUse of additives
29.
INDUSTRIAL UTILIZATION METHOD FOR STEVIA REBAUDIANA AND STEVIOSIDE AND CHLOROGENIC ACID OF STEVIA REBAUDIANA
An industrialization method for comprehensive utilization of stevia rebaudiana. The major improvement is in that the stevia rebaudiana is extracted by using a high-concentration alcohol solution, then the extracted solution is purified by using an organic solvent, and the pH of the extracted solution is adjusted to be alkaline according to the acidic characteristic of chlorogenic acid to enable the chlorogenic acid to be formed into a salt and have an increased polarity so as to achieve effective separation of the chlorogenic acid and a glucoside component in an adsorption process. The method allows the high-quality stevioside and chlorogenic acid to be obtained, significantly improves the comprehensive utilization rate of stevia rebaudiana, reduces the waste of natural stevia rebaudiana resources, reduces the resource consumption in a production process, reduces waste discharge, and is a high-benefit green production process.
Disclosed is a lycopene food colorant having a fresh-keeping function. The food colorant is prepared from the following raw materials in parts by weight: 1-3 parts of a lycopene crystal, 5-20 parts of an emulsifier, 0.5-5 parts of an antioxidant, 60-70 parts of glycerol, and 10-20 parts of water. The food colorant is prepared by mixing the raw materials and then emulsifying and grinding same. The granularity of the obtained lycopene colorant is moderate; the tone is suitable for coloring a minced fillet product; the lycopene colorant has high tinting strength, achieves a bright color, and has the effect of triggering myoglobin, so that the minced fillet product has a bright color and appears fresher; the lycopene colorant further has a fresh-keeping function and can kill some food microorganisms, so as to keep food fresh and prolong the shelf life.
Disclosed is a method for preparing a lycopene micro-capsule powder, wherein lycopene is fully mixed with an aqueous phase to obtain a lycopene emulsified liquid, and the emulsified liquid is then ground to a particle size less than 1 µm, followed by spray drying. The aqueous phase comprises: a gelatin enzymatic hydrolysate with a molecular weight of 5000-10000 Da, disaccharide, polysaccharide, and an antioxidant. The disaccharide is one or more of sucrose, maltose and lactose; and the polysaccharide is one or more of pullulan and chitosan.
The present invention relates to a method for preparing lycopene crystals with high purity and low harm. The method comprises the following steps: (1) mixing lycopene oleoresin with a mixed solvent consisting of an alkane and a lower alcohol, and heating and stirring same for dissolution to form a homogenous solution; (2) cooling and crystallizing the homogenous solution, filtering same to obtain a filter cake; (3) washing the filter cake successively using a lower alcohol and an alkane, and drying same to obtain lycopene crystals. According to the method provided by the present invention, lycopene crystals can be obtained using a mixed solvent by means of one step crystallization, and the crystal content is further improved and harmful substances in the crystals are reduced by means of a two-step crystal washing process to obtain lycopene crystals with high purity and low harm. The method is fast and convenient, lycopene crystals with high purity, low harm, and safety can be produced, and the method is suitable for industrial production.
A pretreatment method for producing lycopene raw material, comprising: tomato skin residue is uniformly mixed with a fermenting agent, an antioxidant and an enzyme preparation and is then subjected to light-proof anaerobic fermentation; employing bacteria enzyme-coupled fermentation technology may prolong the storage period of wet tomato skin residue and break the cell wall of a tomato skin, thus making lycopene easy to extract and improving the purity of late stage lycopene extraction.
A continuous distillation process comprises the following steps: putting a material into a multilayer distillation tower to enable the material to sequentially undergo preheating, extrusion pricking, steam distillation, meal roasting and drying and cooling treatment, condensing essential oil-containing steam, and carrying water separation, so as to obtain essential oil.
A method for identifying the adulteration of a pine bark extract or a peanut skin extract in a grape seed extract using HPLC fingerprint spectrums. The method includes 1) establishing HPLC fingerprint spectrums of the three extracts; 2) determining characteristic peaks of pine bark extract and peanut skin extract; 3) testing a grape seed extract sample using liquid chromatography detection to identify the adulteration of pine bark extract or peanut skin extract in the sample according to whether the chromatogram contains the characteristic peaks of pine bark extract and/or peanut skin extract, wherein the addition of more than 3% of adulterants can be accurately identified. The method has good stability and reproducibility, high efficiency, obvious identification characteristics, provides a theoretical basis for the identification of the plant sources of grape seed extracts, and is conducive to promoting the healthy development of the plant extract industry.
Disclosed is a method for removing benzo[α]pyrene from a liposoluble natural extract. The method of the present invention comprises adding a suitable solvent to a crude natural extract product so as to obtain a mixed material; heating the mixed material, stirring until uniform, cooling and layering, and then separating the upper layer from the lower layer so as to obtain a precipitate and a filtrate; washing the precipitate with a small amount of a solvent so as to obtain a washed product and a washing solution; removing the solvent from the washed product at a low temperature so as to obtain a finished product; and directly recycling the filtrate and the washing solution as solvents. The present method achieves the purification of the crude natural extract product and the removal of benzo[α]pyrene in one step, and is a novel method which is simple, highly efficient, feasible and easy for industrial applications.
C09B 61/00 - Dyes of natural origin prepared from natural sources
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07C 7/00 - Purification, separation or stabilisation of hydrocarbonsUse of additives
B01D 21/26 - Separation of sediment aided by centrifugal force
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Printing ink; colorants; dyes; turmeric [colorant];
colorants for beverages; food dyes; colorants for beer; ink
for skin-dressing. Stain removers; badian essence; essential oils; cake
flavourings [essential oils]; perfumery; aromatics
[essential oils]; flavourings for beverages [essential
oils]; food flavourings [essential oils]; oils for perfumes
and scents; heliotropine. Plant extracts for pharmaceutical purposes; herbal extracts
for medical purposes; dietetic foods adapted for medical
purposes; dietetic beverages adapted for medical purposes;
dietetic substances adapted for medical use; nutritional
supplements; linseed oil dietary supplements; wheat germ
dietary supplements; dietary supplements for animals;
protein supplements for animals. Natural sweeteners; sugar; sugar confectionery; molasses for
food; seasonings; condiments; turmeric; spices; food
flavourings, other than essential oils; flavourings, other
than essential oils, for beverages.
[ Colorants for use in the manufacture of cosmetics; Colorants for use in the manufacture of pharmaceuticals; Synthetic dyes; Synthetic resin colors; Natural dyes; ] Food colorants; Colorants for use in the manufacture of food; Colorants for food and beverages [ ; Cochineal carmine ]
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
[ Linseed oil dietary supplements; Linseed dietary supplements; ] Dietary supplements for animals; [ Herbal extracts for medical purposes; Sugar for medical purposes; ] Animal feed additive for use as a nutritional supplement for medical purposes; [ Soy isoflavone dietary supplements; Wheat germ dietary supplements; Medicinal herbal extracts for medical purposes; ] Nutritional supplements
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
[ Wheat germ for human consumption; Propolis, namely, bee glue for human consumption; ] Natural sweeteners; [ Confectionery, namely, candy and chocolate; Sugar; ] Chili oil for use as a seasoning or condiment; Food seasonings; Spices [ ; Spices in the form of powders ]
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
(1) Colorants for use in the manufacture of cosmetics; Colorants for use in the manufacture of pharmaceuticals; Food dyes; Dyes for making soap; Food colors for domestic use; Colorants for use in the manufacture of food; Colorants for use in the manufacture of beverages; Cochineal carmine; Food colorants.
(2) Herbal extracts for use in the manufacture of cosmetic; Synthetic perfumery; Natural perfumery; Perfumes for industrial purposes; Food flavorings prepared from essential oils; Essential vegetable oils; Essential oils for use as food flavorings; Food flavorings prepared from essential oils; Essential oils for flavouring beverages; Aromatic essential oils.
(3) Linseed oil dietary supplements; Linseed dietary supplements; Linseed dietary supplements for animals; Herbal supplements for general health and well-being; dietetic sugar for medical purposes; Fodder additives for medical purposes; Soy isoflavone dietary supplements; Wheat germ dietary supplements; Mineral dietary supplements for animals; Nutritional supplements for general health and well-being; Yeast dietary supplements for animals.
(4) Wheat germ for human consumption; Propolis (bee glue) for human consumption; Natural sweeteners; Sugar confectionery; Sugar; Chili oil for use as a seasoning or condiment; Food seasonings; Spices; Spices in the form of powders.
43.
Lutein microcapsule formulation and preparation method thereof
A lutein microcapsule formulation and preparation method thereof, the formulation comprising the following ingredients: lutein crystals, a water-soluble emulsifier, an oil-soluble antioxidant, a wall material, a filler, a water-soluble antioxidant, and purified water. The preparation method comprises: dissolving the lutein crystals and the oil-soluble antioxidant in the water-soluble emulsifier to obtain an oil phase; adding the wall material, the water-soluble antioxidant, and the filler to the purified water to obtain a water phase; adding the oil phase to the water phase, grinding to obtain a particle size of the liquid emulsion of less than 100 nm, and granulating.
Disclosed is a method for identifying grape seed extract authenticity using the HPLC fingerprint spectrum, and in particular, a method for identifying the adulteration of a pine bark extract or a peanut skin extract in a grape seed extract. The method comprises the following steps: 1) respectively establishing the HPLC fingerprint spectra of the grape seed extract, the pine bark extract and the peanut skin extract; 2) determining a pine bark extract characteristic peak and a peanut skin extract characteristic peak; 3) subjecting the grape seed extract sample to be tested to liquid chromatography detection, identifying the adulteration of the pine bark extract or the peanut skin extract in the sample to be tested according to whether the chromatogram contains the characteristic peaks of the pine bark extract and/or the peanut skin extract, wherein the addition of more than 3 percent of adulterants can be accurately identified. The method has good stability and reproducibility, high efficiency, obvious identification characteristics, provides a theoretical basis for the identification of the plant sources of grape seed extracts, and is conducive to promoting the healthy development of the plant extract industry.
Disclosed is a method for removing benzo[α]pyrene from a liposoluble natural extract. The method of the present invention comprises adding a suitable solvent to a crude natural extract product so as to obtain a mixed material; heating the mixed material, stirring same until uniform, cooling and layering same, and then separating the upper layer from the lower layer so as to obtain a precipitate and a filtrate; washing the precipitate with a small amount of a solvent so as to obtain a washed product and a washing solution; removing the solvent from the washed product at a low temperature so as to obtain a finished product; and directly recycling the filtrate and the washing solution as solvents. The present method achieves the purification of the crude natural extract product and the removal of benzo[α]pyrene in one step, and is a novel method which is simple, highly efficient, feasible and easy for industrial applications.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07C 7/00 - Purification, separation or stabilisation of hydrocarbonsUse of additives
The present invention relates to a method for producing silymarin. The method comprises: pressing silybum marianum seeds to obtain silymarin powder, and soaking the silymarin powder by using alkaline water; extracting, by using acetone, the silymarin powder soaked by using alkaline water, and performing filtering and concentration on the extracted liquid to obtain a concentrated solution; and performing extraction on the concentrated solution by using a non-polar solvent, performing separation to obtain a non-polar solvent layer and an acetone layer, and concentrating and drying the acetone layer to obtain silymarin. The method can greatly improve the extraction efficiency and the yield, shorten the extraction time, needs simple processes and low cost and thoroughly remove residual oil, so that the product has a low impurity, high product quality and a high purity; and the method is applicable to industrial production and has a great application prospect and economic value.
C07D 407/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
47.
LUTEIN MICROCAPSULE PREPARATION AND PREPARATION METHOD
A lutein microcapsule preparation and preparation method, the preparation comprising the following ingredients: lutein crystals, a water-soluble emulsifier, an oil-soluble antioxidant, a wall material, a filler, a water-soluble antioxidant, and purified water. The preparation method comprises: dissolving the lutein crystals and the oil-soluble antioxidant in the water-soluble emulsifier to obtain an oil phase; adding the wall material, the water-soluble antioxidant, and the filler to the purified water to obtain a water phase; adding the oil phase to the water phase, grinding to obtain a particle size of the liquid emulsion of less than 100 nm, and granulating.
A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 39/00 - General protective or antinoxious agents
48.
METHOD FOR EXTRACTING CAPSANTHIN AND CAPSAICIN FROM FRESH CHILES
Disclosed is a method for extracting capsanthin and capsaicin from fresh chiles, which relates to the field of natural plant extracts. The method comprises the following steps: (1) crushing of fresh chiles: crushing the fresh chiles, separating the seed and husk, obtaining the crushed fresh chiles and then collecting same for use; (2) fermentation: spraying a microbial strain on the crushed fresh chiles homogeneously, fermenting same under an anaerobic condition, and obtaining the fermented crushed chilies, wherein the fermented crushed chilies are processed to form chili granules for use in the extraction of capsanthin and capsaicin. The beneficial effects of the method are as follows: 1. it can meet the requirements of the mechanized picking of chilies, and greatly improve efficiency; 2. since the fermentation of fresh chilies is anaerobic fermentation under a dark condition, there is substantially no loss of pigments, and moreover, the fermented crushed chilies can be stored for up to twelve months under a sealed dark condition, thus the processing period is extended, and the enterprise can arrange a production plan rationally according to circumstances; and 3. it improves the quality of the finished products of capsanthin and capsaicin by fermentation.
The present invention relates to a method for producing silymarin. The method comprises: pressing silybum marianum seeds to obtain silymarin powder, and soaking the silymarin powder by using alkaline water; extracting, by using acetone, the silymarin powder soaked by using alkaline water, and performing filtering and concentration on the extracted liquid to obtain a concentrated solution; and performing extraction on the concentrated solution by using a non-polar solvent, performing separation to obtain a non-polar solvent layer and an acetone layer, and concentrating and drying the acetone layer to obtain silymarin. The method can greatly improve the extraction efficiency and the yield, shorten the extraction time, needs simple processes and low cost and thoroughly remove residual oil, so that the product has a low impurity, high product quality and a high purity; and the method is applicable to industrial production and has a great application prospect and economic value.
C07D 407/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
50.
GREEN COFFEE BEAN EXTRACT AND PRODUCTION METHOD THEREOF
Provided is a method for producing green coffee bean extract, the method comprising: conducting supercritical carbon dioxide treatment on green coffee bean raw material, and then employing organic solvent extraction to obtain the green coffee bean extractive. The obtained green coffee bean extractive product mainly contains 28-37% 5-caffeoylquinic acid, and 45-60% total chlorogenic acid. The present invention has no harmful residual solvent, dramatically reduces pesticide residue, and ensures no loss of content of effective ingredients while removing caffeine; the obtained green coffee bean extract product has high weight yield, high earnings, and low costs, greatly increases the content of effective ingredients, and is superior to the prior art, thus being suitable for large-scale industrial production and having broad application prospects and economic value.
A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon. The process uses the by-products of tomato production as raw material, thus increasing the utilization ratio of tomatoes; the way of separating the seeds and skins after dehydrating and drying can save water and reduce the discharge of pollutant; the addition of antioxidant in the process of drying avoids the impact of high temperature on lycopene; extracting after granulating the tomato skins significantly increases the extracting efficiency; treating the extracting solution with active carbon effectively can remove the pesticide residues, impurities, odor etc., and thus increase the quality of lycopene.
C10G 1/00 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal
C09B 61/00 - Dyes of natural origin prepared from natural sources
Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize. According to the application, organic solvents are used to treat the plant extract and remove non-xanthophyll ester compounds in order to improve the efficiency of the saponification reaction; the saponified solution is concentrated under acidic condition at reduced pressure, then extracted with an organic solvent for saving water; purifying a xanthophyll crystal with a mixed solvent in order to significantly increase the purity of a xanthophyll crystal and proportion of trans-xanthophyll.
C07C 35/21 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a non-condensed ring
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Bee glue; molasses for food; seasonings; turmeric for food;
spices; flavorings, other than essential oils; flavorings,
other than essential oils, for cakes; flavorings, other than
essential oils, for beverages; chili oil; essences for
foodstuffs (except etheric essences and essential oils).
Disclosed is a method for preparing lutein crystal, comprising: a plant extract containing lutein esters is dissolved in n-hexane and filtered; the filter cake is dissolved in acetone, filtered and the filter cake is collected; the filter cake is mixed with a soybean oil and ethanol homogeneously; the product is saponified with an alkaline aqueous solution, and after the saponification an acid solution is added to the mixture in order to make same acidic and concentrated under reduced pressure to obtain a pasty material; n-hexane is added to the pasty saponified product, and after standing, the solid phase and liquid phase are separated; the solid material is washed with de-ionized water; a mixed solvent is added to the washed solid and dissolved with stirring; and after n-hexane is added again, the product is re-crystallized by standing. In the present invention, an organic solvent is employed to treat the plant extract and the compounds of non-lutein esters are removed, which can improve the efficiency of saponification; the saponified liquid is concentrated under reduced pressure under acidic conditions and then is extracted with an organic solvent, which can save water; and a mixed solvent is employed to purify the lutein crystal, which can significantly improve the purity of the lutein crystal and the ratio of trans-lutein.
C07C 37/68 - SeparationPurificationStabilisationUse of additives
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
C07C 35/21 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a non-condensed ring
Disclosed is a method for extracting lycopene, comprising: firstly raw materials containing lycopene are dehydrated; then the dehydrated raw materials are dried in the presence of an antioxidant; the dried raw materials are pulverized roughly and then separated by winnowing; the part of the raw materials with a relatively low density is finely pulverized and granulated; the resulting granules are extracted with an organic solvent; the extracts are treated with active carbon, followed by filtration; and then the filtrate is concentrated to obtain a lycopene product.
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Chili oil for use as a seasoning or condiment; Flavorings; Flavorings for beverages, other than essential oils; Flavourings for cakes other than essential oils; Food flavorings; [ Molasses; Propolis for human consumption; ] Seasonings; Spices; Turmeric
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
[ Air purifying preparations; All purpose disinfectants; Chemical conductors for use with electrocardiograph electrodes; Cleansing solutions for medical use; Contact lens cleaning preparations; Gases for medical and dental use; ] Health food supplements; [ Isotopes for medical purposes; ] Nutritional supplements; Nutritive substances for microorganisms for medical purposes
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
21 - HouseHold or kitchen utensils, containers and materials; glassware; porcelain; earthenware
31 - Agricultural products; live animals
Goods & Services
(1) Textile dyes; Colourants for use in the manufacture of paint; Colourants for use in the manufacture of food; Ink; Primer paint; Anti-corrosive paint; Natural resin; Ink cartridges for printer. Bar soaps; Laundry detergents; Household detergents; Polishing cloth; General use abrasives; Perfume; Cosmetics; Toothpaste; Incense; Malt for brewing and distilling
63.
PROCESS FOR EXTRACTING PLANT-DERIVED NATURAL PRODUCTS WITH POLARITY OR INTERMEDIATE POLARITY
A process for extracting plant-derived natural products with polarity or intermediate polarity is provided. Said process involves the following steps: crushing the plant-derived materials containing natural products with polarity or intermediate polarity, adding water, and circularly introducing CO2 with high pressure into the extracting apparatus. During the extracting process, the temperature is 40-90℃, the pressure is 5-50 MPa, and the treatment time with high pressure CO2 is 1-60 minutes. Said process can be used to extract polar natural products such as anthocyanins, or other natural products with polarity or intermediate polarity.
