Described herein is an acerola cherry (Malpighia emarginata DC.) variety designated Nutrilite Acerola Super C, plants thereof, seed thereof, hybrids thereof, products thereof, and cultivars derived therefrom. The Nutrilite Acerola Super C variety has greater fruit yield, greater fruit mass, greater productivity, greater amounts of vitamin C, greater amounts of polyphenols, greater amounts of antioxidants, improved fruit firmness, and greater juice yields, among other desirable phenotypic or genotypic characteristics, as compared to other varieties of acerola plants or wild-type acerola.
Provided is a multilayer formulation. The multilayer formulation is useful for controlled-release and immediate-release of active agents after administration to a subject. The multilayer formulation comprises a first layer comprising a controlled-release composition, and a second layer disposed adjacent the first layer and comprising an immediate-release composition. The controlled-release composition of the first layer comprises a first active agent and a controlled-release excipient comprising a modified tapioca starch. The modified tapioca starch provides for controlled-release of the first active agent from the first layer. The immediate-release composition of the second layer comprises a second active agent and an excipient. The multilayer formulation can be in the form of a tablet, such as a bilayer tablet. The multilayer formulation may be administered orally to a subject to provide various types of active agents (e.g., vitamins, minerals, botanicals, etc.) at different locations of the subject's gastrointestinal (GI) tract.
COMPOSITIONS COMPRISING CAROTENOIDS AND/OR BILBERRY FOR PROTECTING THE EYES OF A MAMMALIAN SUBJECT FROM OR REDUCING OR TREATING DAMAGE DUE TO EXPOSURE TO BLUE LIGHT
Described herein are methods and compositions that comprise an amount of at least one active agent, such as at least one carotenoid and an ingredient or extract of bilberry, preferably an amount of at least one of: lutein, zeaxanthin, β-carotene, lycopene, and an ingredient or extract of bilberry; and an additive.
A composition for administration to a subject is provided. The composition comprises at least one botanical active component present in an amount effective to inhibit on or more of α-glucosidase, lipase, and xanthine oxidase in the subject. The botanical active component comprises, consists essentially of, or is Mongolidine F. The composition may be in the form of an oral composition, e.g., for ingestion, or in the form of a topical composition, e.g., for topical application. Use of the composition for inhibiting at least one of α-glucosidase, lipase, and xanthine oxidase in a subject, and use of the composition in preparing a medicine for treatment of at least one of hyperglycemia, hyperlipidemia, and hyperuricemia, are also provided. A method of inhibiting at least one of α-glucosidase, lipase, and xanthine oxidase in a subject is also provided. The method comprises administering an effective amount of the composition to the subject.
NN 1NN 10-caffeoylspermidine that maintains cell viability for subsequent exposure to UVB radiation and repairs genetic damage caused by UVB radiation is provided.
Provided herein are compositions and method for treating and preventing skin damage. In particular, provided herein are compositions that reverse, prevent and/or slow age-related skin damage.
A system and method for automating the identification of botanicals and detection of adulterants based on High Performance Thin-Layer Chromatography ("HPTLC") images. The system and method includes a first neural network that augments an existing HPTLC image dataset with synthetic data created using an adversarial machine learning model. For example, the synthetic data may be created using a generative adversarial network (GAN). The system and method further includes a second neural network that is trained on a combination of real data and synthetic data produced by the adversarial machine learning model. For example, the second neural network may be a deep convolutional neural network (CNN). Following training, the CNN performs the identification of botanicals and detection of adulteration through machine vision-based analysis of the output image data corresponding to phytochemical composition from HPTLC. The system may provide confidence-based probabilities and other numerical outputs related to the identify and adulteration determinations.
Described herein are methods and compositions for use in treating, preventing or reversing aging or age-related diseases, disorders or conditions. Also, described herein are methods and compositions for selective killing of senescent cells that are associated with numerous pathologies and diseases, including age-related pathologies, diseases and conditions. As disclosed herein are methods where senescent cell associated diseases and disorders may be treated or prevented (i.e., likelihood of occurrence or development is reduced) by administering the described compositions.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A liquid chemical applicator used for scalp care is provided. The liquid chemical applicator includes a container accommodating liquid chemical, an inner cap coupled to the container, and an outer cap rotatably and movably coupled to the inner cap. The inner cap includes a bush portion coupled to an outlet hole of the container along a central axis of the outlet hole. The outer cap includes a plug portion blocking and opening the bush portion, and further discharges the liquid chemical introduced through the bush portion. The outer cap blocks or opens the bush portion by rotation in first and second rotation directions centered on the central axis and by movement in first and second movement directions along the central axis.
B65D 47/14 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages having removable closures and closure-retaining means
B65D 47/12 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages having removable closures
10.
SYSTEM AND METHOD FOR AUTONOMOUS BOTANICAL IDENTIFICATION AND ADULTERATION DETECTION
A system and method for automating the identification of botanicals and detection of adulterants based on High Performance Thin-Layer Chromatography (“HPTLC”) images. The system and method includes a first neural network that augments an existing HPTLC image dataset with synthetic data created using an adversarial machine learning model. For example, the synthetic data may be created using a generative adversarial network (GAN). The system and method further includes a second neural network that is trained on a combination of real data and synthetic data produced by the adversarial machine learning model. For example, the second neural network may be a deep convolutional neural network (CNN). Following training, the CNN performs the identification of botanicals and detection of adulteration through machine vision-based analysis of the output image data corresponding to phytochemical composition from HPTLC. The system may provide confidence-based probabilities and other numerical outputs related to the identify and adulteration determinations.
Potentilla glabraPotentilla glabra; ii) thonningianin A; and iii) combinations of i) and ii). The composition may be in the form of an oral composition, e.g., for ingestion. The composition may also be in the form of a topical composition, e.g., for topical application. A method of inhibiting 5α-reductase in a subject is also provided. The method comprises administering an effective amount of the composition to the subject.
A61K 36/73 - Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
A method of preparing a Polygonatum polysaccharide composition is provided. The method includes performing a first extraction of Polygonatum material to obtain a first residue; performing a second extraction of the first residue to obtain a second residue; performing a third extraction of the second residue to obtain a supernatant, and precipitating the supernatant with a solvent to obtain crude polysaccharides; performing elution of the crude polysaccharides with a first eluent to obtain a first eluate; and performing filtration of the first eluate. A Polygonatum polysaccharide composition obtained by the method, an oral composition including the Polygonatum polysaccharide composition, a use of the Polygonatum polysaccharide composition in preparing a medicine for treatment of ulcerative colitis (UC) in a subject, and a method of treating UC in a subject are also provided. The Polygonatum polysaccharide composition comprises, consists essentially of, or is an isolated polysaccharide of a particular structure described herein.
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
13.
METHOD OF HIGH THROUGHPUT SCREENING (HTS) FOR BIOACTIVES
A screening method for the high-throughput detection of phytochemicals is provided. The method includes exposing an extract cell group to a plant extract to form an exposed cell group. Exposed signals generated by the extract cell group and control signals generated by the control group are measured and compared to generate a signal list consisting of exposed signals that satisfy an inclusion condition. The exposed signals of the signal list are compared to a list of pre-determined phytochemical signatures to generate a known phytochemical list and/or an unknown phytochemical list. The known phytochemical list includes phytochemicals having phytochemical signatures substantially matching one of the exposed signals of the signal list, and the unknown phytochemical list consists of all other phytochemicals. A chemical database comprising phytochemical associations with chemicals to generate a reactive chemical list for each phytochemical of the known phytochemical list.
A method useful for providing a phytonutrient to a subject via mediation of the subject's microbiome is disclosed. The method includes administering a phytofunctional composition to a subject change the phytonutrient-producer status of the subject. The method may also include identifying a phytonutrient-producer status of the subject by assessing a level of at least one of a preselected phytonutrient and a preselected phytonutrient precursor compound within the subject. A phytofunctional composition useful in the method is also disclosed, and comprises a phytonutrient precursor compound and an active agent. The active agent comprises a probiotic and/or a prebiotic, and is adapted to mediate production of the preselected phytonutrient in the gastrointestinal tract of the subject, thereby changing the phytonutrient-producer status of the subject.
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A skin treatment device configured to selectively operate in hydradermabrasion mode and in massage mode. The skin treatment device includes a working end and a plurality of interchangeable working attachments that can be selectively mounted to the working end. The working attachments includes at least one hydradermabrasion tip and at least one massage head. The device includes a liquid delivery system for moving liquid from a supply canister to the working attachment and from the working attachment to the waste receptacle. The hydradermabrasion tip includes a supply aperture for delivering liquid to the target region of skin and a return aperture for returning liquid from the target region to the waste receptacle. The device may include a red-light therapy system for delivering red-light therapy to a target region. The red-light therapy system may include a plurality of red LEDs positioned to emit red light through an installed working attachment.
A cap device for scalp care is provided. The cap device includes an interior cover, an exterior cover coupled to the interior cover, a substrate, and a blower. The interior cover covers the scalp, and has emitting holes for emitting air. The exterior cover defines an air flow passage along the interior cover, and has a vent hole for sucking air. The substrate is coupled to the interior cover in the air flow passage to cover an outer surface of the interior cover. The substrate has laser diodes, infrared ray and red light emitting diodes, and through holes corresponding to the emitting holes. The blower communicates with the air flow passage at an upper end of the interior cover. The blower sucks air through the vent hole and emits the air to the scalp through the emitting holes via the air flow passage.
An Orris root extract is disclosed. The Orris root extract is obtained via Orris root materials via selective extraction, and is selectively enriched in (A) a phytochemical melanogenesis stimulating agent or (B) a phytochemical melanogenesis inhibiting agent. The phytochemical melanogenesis stimulating agent (A) comprises germanaism B, and the phytochemical melanogenesis inhibiting agent (B) comprises iriflorental and/or iripallidal. A method of preparing the Orris root extract composition is also provided, and includes selectively extracting an Orris root materials to give at least one Orris root extract. A functional composition comprising the Orris root extract is also provided. The functional composition is adapted for administration to a subject via topical application, and demonstrates activity relating to skin pigmentation.
Lycium ruthenicumCaenorhabditis elegansCaenorhabditis elegans is provided. The extract may include compounds that inhibit the activity of histone deacetylases and that are specific inhibitors of HDAC8.
Lycium ruthenicumLycium ruthenicum fruit to provide the extract as a product is further provided. A method of inhibiting a histone deacetylase is further provided.
The described invention relates to a composition for preventing, treating, or relieving menstrual symptoms or discomforts and providing mood improvement in a female patient comprising: (i) an ingredient or an extract of chasteberry fruit; (ii) an ingredient or an extract of saffron red sargol stigma, wherein the ingredient or the extract of saffron red sargol stigma is encapsulated by maltodextrin; and (iii) an excipient. The described invention also relates to a method of using the composition for prevention and amelioration of common menstrual cycle symptoms and/or discomforts in female subjects.
The described invention relates to a composition for preventing, treating, or relieving menstrual symptoms or discomforts and providing mood improvement in a female patient comprising: (i) an ingredient or an extract of chasteberry fruit; (ii) an ingredient or an extract of saffron red sargol stigma, wherein the ingredient or the extract of saffron red sargol stigma is encapsulated by maltodextrin; and (iii) an excipient. The described invention also relates to a method of using the composition for prevention and amelioration of common menstrual cycle symptoms and/or discomforts in female subjects.
A61K 36/53 - Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
A61K 36/48 - Fabaceae or Leguminosae (Pea or Legume family)CaesalpiniaceaeMimosaceaePapilionaceae
A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
26.
COMPOSITION FOR PROMOTING MOISTURE ABSORPTION AND RETENTION IN SKIN AND METHOD OF PREPARING THE COMPOSITION
Salvia hispanicaSalvia hispanicaSalvia hispanica seed to form a mixture; adding a bacteria strain to the mixture; subjecting the mixture to fermentation for a time period of at least 48 hours; and subjecting the fermented mixture to high pressure homogenization to form a nanoemulsion. A method of promoting moisture absorption and retention in skin of a subject is also provided. The method comprises topically administering the composition to the skin of the subject.
Potentilla glabraBombax malabaricumAmomum villosumAmomum kravanhCornus officinalis Cornus officinalis fruit; and vi) combinations of i) to v). The composition may be in the form of a topical composition, e.g., for topical application. The composition may also be in the form of an oral composition, e.g., for ingestion. A method of inhibiting elastase activity in the skin of a subject is also provided. The method comprises administering an effective amount of the composition to the subject.
Potentilla glabraBombax malabaricumAmomum kravanhCornus officinalis Cornus officinalis fruit; and v) combinations of i) to iv). The composition may be in the form of a topical composition, e.g., for topical application. The composition may also be in the form of an oral composition, e.g., for ingestion. A method of inhibiting collagenase activity in the skin of a subject is also provided. The method comprises administering an effective amount of the composition to the subject.
Dendrobium officinaleScrophularia ningpoensisEucommia ulmoidesEucommia ulmoides; and iv) combinations of i) to iii). The composition may be in the form of a topical composition, e.g., for topical application. The composition may also be in the form of an oral composition, e.g., for ingestion. A method of inhibiting advanced glycation end products (AGEs) in skin of a subject is also provided. The method comprises administering an effective amount of the composition to the subject.
Provided is a multilayer formulation. The multilayer formulation is useful for controlled-release and immediate-release of active agents after administration to a subject. The multilayer formulation comprises a first layer comprising a controlled-release composition, and a second layer disposed adjacent the first layer and comprising an immediate-release composition. The controlled-release composition of the first layer comprises a first active agent and a controlled-release excipient comprising a modified tapioca starch. The modified tapioca starch provides for controlled-release of the first active agent from the first layer. The immediate-release composition of the second layer comprises a second active agent and an excipient. The multilayer formulation can be in the form of a tablet, such as a bilayer tablet. The multilayer formulation may be administered orally to a subject to provide various types of active agents (e.g., vitamins, minerals, botanicals, etc.) at different locations of the subject's gastrointestinal (GI) tract.
A method useful for providing a phytonutrient to a subject via mediation of the subject’s microbiome is disclosed. The method includes administering a phytofunctional composition to a subject change the phytonutrient producer status of the subject. The method may also include identifying a phytonutrient producer status of the subject by assessing a level of at least one of a preselected phytonutrient and a preselected phytonutrient precursor compound within the subject. A phytofunctional composition useful in the method is also disclosed, and comprises a phytonutrient precursor compound and an active agent. The active agent comprises a probiotic and/or a prebiotic, and is adapted to mediate production of the preselected phytonutrient in the gastrointestinal tract of the subject, thereby changing the phytonutrient producer status of the subject.
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A UV reactor for disinfecting water and including a UV source printed circuit board assembly transfers heat to a heat sink in the form of a water facing thermal coupler. The UV source printed circuit board assembly may include a metal clad printed circuit board having a thermal contact region in thermal communication with the heat sink.
Provided herein are compositions and method for treating and preventing skin damage In particular, provided herein re compositions that reverse, prevent and/or slow age-related skin damage.
A cap device for scalp care is provided. The cap device comprises an inner cover, an outer cover coupled to the inner cover, a substrate, and a blower. The inner cover covers the scalp, and has an ejection hole for ejecting air. The outer cover defines an airflow passage along the inner cover, and has a ventilation hole for sucking in air. The substrate is coupled to the inner cover so as to cover the outer surface of the inner cover in the airflow passage. The substrate has a laser diode, infrared and red light emitting diodes, and a through hole corresponding to the ejection hole. The blower communicates with the airflow passage at the top end of the inner cover. The blower sucks in air through the ventilation hole, and ejects the air to the scalp through the ejection hole via the airflow passage.
An Orris root extract is disclosed. The Orris root extract is obtained via Orris root materials via selective extraction, and is selectively enriched in (A) a phytochemical melanogenesis stimulating agent or (B) a phytochemical melanogenesis inhibiting agent. The phytochemical melanogenesis stimulating agent (A) comprises germanaism B, and the phytochemical melanogenesis inhibiting agent (B) comprises iriflorental and/or iripallidal. A method of preparing the Orris root extract composition is also provided, and includes selectively extracting an Orris root materials to give at least one Orris root extract. A functional composition comprising the Orris root extract is also provided. The functional composition is adapted for administration to a subject via topical application, and demonstrates activity relating to skin pigmentation.
A UV reactor for disinfecting water. The UV reactor may include a cooling chamber in which heat from a UV source may be transferred to the water flowing through the UV reactor. The UV reactor may include driver circuitry operable to determine status information, such as health, of the UV source. The UV reactor may include a gas discharge path operable to substantially prevent accumulation of gas within a water treatment chamber.
Provided herein are compositions and method for treating and preventing skin damage. In particular, provided herein are compositions that reverse, prevent and/or slow age-related skin damage.
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
A water treatment system is provided with an untreated water reservoir having a cavity through which a filter assembly may traverse such that untreated water in the cavity passes through the filter assembly into a treated water reservoir. Removal of the filter assembly may be facilitated by a seal disengagement element operable to unseat a seal formed during efforts to direct untreated water through the filter assembly.
A method useful for providing a phytonutrient to a subject via mediation of the subject's microbiome is disclosed. The method includes administering a phytofunctional composition to a subject change the phytonutrient producer status of the subject. The method may also include identifying a phytonutrient producer status of the subject by assessing a level of at least one of a preselected phytonutrient and a preselected phytonutrient precursor compound within the subject. A phytofunctional composition useful in the method is also disclosed, and comprises a phytonutrient precursor compound and an active agent. The active agent comprises a probiotic and/or a prebiotic, and is adapted to mediate production of the preselected phytonutrient in the gastrointestinal tract of the subject, thereby changing the phytonutrient producer status of the subject.
A product interaction monitor includes sensors for measuring characteristics related to the product and/or product package or other type of container. The product interaction monitor can be installed in a container cap and used to monitor events associated with the container such as product usage. The product interaction monitor can utilize multiple sensor outputs to increase the accuracy of the detection of the events. The product interaction monitor can be used to estimate product inventory or product usage and communicate information regarding the product and/or product usage to a local display or a remote computer.
A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
B65D 51/24 - Closures not otherwise provided for combined with auxiliary devices for non-closing purposes
B65D 41/04 - Threaded or like caps or cap-like covers secured by rotation
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G08B 21/24 - Reminder alarms, e.g. anti-loss alarms
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
52.
Method of increasing the level and production of metabolized phytonutrients in a subject
A method useful for providing a phytonutrient to a subject via mediation of the subject's microbiome is disclosed. The method includes administering a phytofunctional composition to a subject change the phytonutrient producer status of the subject. The method may also include identifying a phytonutrient producer status of the subject by assessing a level of at least one of a preselected phytonutrient and a preselected phytonutrient precursor compound within the subject. A phytofunctional composition useful in the method is also disclosed, and comprises a phytonutrient precursor compound and an active agent. The active agent comprises a probiotic and/or a prebiotic, and is adapted to mediate production of the preselected phytonutrient in the gastrointestinal tract of the subject, thereby changing the phytonutrient producer status of the subject.
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A UV reactor for disinfecting water. The UV reactor may include a cooling chamber in which heat from a UV source may be transferred to the water flowing through the UV reactor. The UV reactor may include driver circuitry operable to determine status information, such as health, of the UV source. The UV reactor may include a gas discharge path operable to substantially prevent accumulation of gas within a water treatment chamber.
A UV reactor for disinfecting water. The UV reactor may include a cooling chamber in which heat from a UV source may be transferred to the water flowing through the UV reactor. The UV reactor may include driver circuitry operable to determine status information, such as health, of the UV source. The UV reactor may include a gas discharge path operable to substantially prevent accumulation of gas within a water treatment chamber.
A protein hydrolysate composition is provided. The protein hydrolysate composition comprises isolated peptides useful for ameliorating a condition of a subject. Compositions comprising the protein hydrolysate composition are also provided. The compositions may be adapted for oral or topical administration to the subject, and may compose a foodstuff or beverage (e.g. a medical food), a topical composition (e.g. a lotion, cream, etc.), a kit, and the like. A methods of ameliorating the condition of the subject is further provided. The method include administering the protein hydrolysate composition to the subject. The method may be useful in reducing blood pressure, inflammation, reduced immunity, and/or oxidative stress in the subject.
A topical composition comprising a mucilage plant extract is provided. The topical composition is formulated for administration to a subject, and may be provided in the form of a skin toner. Methods of preparing the topical composition are also provided, and include combining a mucilage plant extract and a pharmaceutically acceptable additive. The topical composition may be used to control the skin microbiome of a subject, and likewise for treating certain skin conditions involving pathogenic bacteria. A method of ameliorating a skin condition of a subject is therefore also provided. The method generally includes topically administering the topical composition to the skin of the subject, and may be used in ameliorating skin conditions including inflammation and/or decreased epidermal barrier function.
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A protein hydrolysate composition is provided. The protein hydrolysate composition comprises isolated peptides useful for ameliorating a condition of a subject. Compositions comprising the protein hydrolysate composition are also provided. The compositions may be adapted for oral or topical administration to the subject, and may compose a foodstuff or beverage (e.g. a medical food), a topical composition (e.g. a lotion, cream, etc.), a kit, and the like. A methods of ameliorating the condition of the subject is further provided. The method include administering the protein hydrolysate composition to the subject. The method may be useful in reducing blood pressure, inflammation, reduced immunity, and/or oxidative stress in the subject.
A water treatment system having a base assembly and a treatment assembly. The treatment assembly of the system may be configured to filter particulates from water. The base assembly may include a UV reactor operable to disinfect water for consumption.
B01D 29/15 - Supported filter elements arranged for inward flow filtration
B01D 29/96 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor in which the filtering elements are moved between filtering operationsParticular measures for removing or replacing the filtering elementsTransport systems for filters
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
B01D 29/11 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with bag, cage, hose, tube, sleeve or like filtering elements
A water treatment system having a base assembly and a treatment assembly. The treatment assembly of the system may be configured to filter particulates from water. The base assembly may include a UV reactor operable to disinfect water for consumption.
B01D 29/15 - Supported filter elements arranged for inward flow filtration
B01D 29/96 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor in which the filtering elements are moved between filtering operationsParticular measures for removing or replacing the filtering elementsTransport systems for filters
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
B01D 29/11 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with bag, cage, hose, tube, sleeve or like filtering elements
A water treatment system having a base assembly and a treatment assembly. The treatment assembly of the system may be configured to filter particulates from water. The base assembly may include a UV reactor operable to disinfect water for consumption.
C02F 1/00 - Treatment of water, waste water, or sewage
B01D 27/02 - Cartridge filters of the throw-away type with cartridges made from a mass of loose material
C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
B65D 6/00 - Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal, plastics, wood or substitutes therefor
F21V 8/00 - Use of light guides, e.g. fibre optic devices, in lighting devices or systems
A water treatment system having a base assembly and a treatment assembly. The treatment assembly of the system may be configured to filter particulates from water. The base assembly may include a UV reactor operable to disinfect water for consumption.
B01D 29/15 - Supported filter elements arranged for inward flow filtration
B01D 29/96 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor in which the filtering elements are moved between filtering operationsParticular measures for removing or replacing the filtering elementsTransport systems for filters
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
B01D 29/11 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with bag, cage, hose, tube, sleeve or like filtering elements
63.
Nano-enabled activated carbon blocks to enable removal of oxyanions from water
Arizona Board of Regents on behalf of Arizona State University (USA)
Inventor
Cai, Zhenxiao
Mollema, Scott A.
Atkinson, Ariel J.
Hristovski, Kiril D.
Markovski, Jasmina S.
Westerhoff, Paul K.
Abstract
A method for preparing a nano-enabled activated carbon block, a nano-enabled activated carbon block produced by the method, a household water filtration system comprising the nano-enabled activated carbon block, and a method for filtering tap water using the household water filtration system are provided. The method includes contacting a solution including a metal(lic) precursor (e.g. a titanium compound and/or an iron compound and/or a zirconium compound) with activated carbon particles such that the solution fills pores of the activated carbon particles. The method further includes causing a metal (hydr)oxide (e.g. titanium dioxide and/or zirconium dioxide and/or iron oxide) to precipitate from the solution thereby causing metal oxide nanoparticles to become deposited within pores of the activated carbon particles. The method also includes preparing a nano-enabled activated carbon block from the activated carbon particles having metal oxide nanoparticles deposited within the pores thereof.
B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
B01J 20/30 - Processes for preparing, regenerating or reactivating
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
A water treatment system is provided with an untreated water reservoir having a cavity through which a filter assembly may traverse such that untreated water in the cavity passes through the filter assembly into a treated water reservoir. Traversal of the filter assembly may be facilitated by a pressure control assembly as a vacuum pump in order to generate a vacuum in a treated water reservoir connected to the filter assembly.
A water treatment system is provided with an untreated water reservoir having a cavity through which a filter assembly may traverse such that untreated water in the cavity passes through the filter assembly into a treated water reservoir. Traversal of the filter assembly may be facilitated by a pressure control assembly configured to generate a vacuum.
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
B01D 29/60 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor integrally combined with devices for controlling the filtration
The present disclosure relates to a smart diffuser. The smart diffuser of the present disclosure includes a frame configured to define a diffusing position, a container mounted on the frame and including a space configured to mount a plurality of oil cartridges therein, and a driving unit configured to drive the container. The driving unit drives the container so as to cause a cartridge selected by a user among the plurality of oil cartridges to enter the diffusing position.
The present disclosure relates to a method of operating a smart diffuser using a terminal connected to the smart diffuser via a network and a terminal therefor. The method of operating the smart diffuser using the terminal includes generating a mode selection signal comprising operation information on a plurality of oil cartridges mounted in the smart diffuser, wherein the operation information comprises at least one of an operation order, an operation duration, a fragrance emission intensity, and an operation time zone of each of the cartridges; and transmitting the mode selection signal to the smart diffuser. The present disclosure relates to a method of operating a smart diffuser (200) using a terminal (100) connected to the smart diffuser (200) via a network and a terminal therefor. The method of operating the smart diffuser (200) using the terminal (100) includes generating (S 10) a mode selection signal comprising operation information on a plurality of oil cartridges (CA) mounted in the smart diffuser (200), wherein the operation information comprises at least one of an operation order, an operation duration, a fragrance emission intensity, and an operation time zone of each of the cartridges (CA); and transmitting (S20) the mode selection signal to the smart diffuser (200).
Compositions for preventing, treating and/or curing human skin from an air pollution-induced damage and methods of using the compositions are described. One embodiment relates to a cosmetic composition comprising an isolated ingredient or an extract of Dendrobium nobile, in a working amount sufficient for at least one of: reducing or preventing air pollution-induced or air pollution inducible skin and/or hair damage; reducing or preventing air pollution-induced oxidative stress; reducing or preventing air pollution-induced decrease in cell vitality; reducing or preventing air pollution-induced increase in IL-6; or reducing or preventing air pollution-induced cell damage; and a cosmetically acceptable carrier or excipient.
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin
A power dispensing closure capable of being retrofitted to existing powder containers to allow metered dispensing of powder from conventional powder containers. The closure may include a metering disk enclosed within an interior space, and movable between a closed position in which the metering disk may be loaded with powder material from the container and a dispense position in which the metering disk is capable of dispensing the loaded material from the closure. The closure may include a metering disk actuator extending from the metering disk through a slot in the housing. The closure may include a bottom housing configured to install on a powder container in place of a conventional cap. The housing may include a load opening for loading the metering disk and a spout for dispensing the loaded powder. The load opening and spout may be radially offset no more than about ninety degrees.
G01F 11/24 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
G01F 11/00 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
Salvia hispanicaSalvia hispanica L.) variety designated Rehnborg, seed thereof, hybrids thereof, products thereof, and cultivars derived therefrom. The Rehnborg variety has uniform white seed, greater seed mass, and greater seed yields compared to other typical chia varieties or wild-type chia.
Salvia hispanica L.) variety designated Rehnborg, seed thereof, hybrids thereof, products thereof, and cultivars derived therefrom. The Rehnborg variety has uniform white seed, greater seed mass, and greater seed yields compared to other typical chia varieties or wild-type chia.
A method is disclosed. The method is generally useful for modifying a skin microbiome. The method comprises administering a topical composition to a subject's skin. A topical composition is also disclosed. The topical composition may be used for the method. The topical composition comprises a population of microorganisms, a component obtained from the population of microorganisms, or a combination thereof. The population of microorganisms is generally a Corynebacterium species. The Corynebacterium species comprises at least about 90%, optionally at least about 97%, sequence identity to a 16S rRNA sequence (SEQ ID NO: 1).
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
The present disclosure relates to a skin-cleansing device. The skin-cleansing device of the present disclosure comprises: a body on the end of which there is a cleansing unit, and on the inside of which is provided a first electrical-power storing unit for storing electrical power whereby the cleansing unit is made to vibrate; and a cradle on the inside of which is formed an accommodation space so as to hold the body, with the cleansing unit in a downward-facing state, and which is provided with a second electrical-power storing unit for storing electrical power whereby the first electrical-power storing unit is charged.
A composition comprising an effective amount of a wheat peptide and an effective amount of fucoidan. The composition further comprises an effective amount of at least one component or extract from among white peony root, Magnolia officinalis or Asiatic pennywort herb in combination with the wheat peptide and fucoidan. The composition may prevent and reduce Helicobacter pylori infections as well as gastric mucosal injuries which are caused by non-steroidal anti-inflammatory drugs, drinking, unhealthy eating habits, and stress, may regulate oxidative stress markers and anti-inflammatory markers in subjects, inhibit the generation of interleukin 8 (IL-8) and malondialdehyde (MDA), and increase the generation of superoxide dismutase (SOD) and prostaglandin E2 (PGE2).
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A composition for treating skin pigmentation, a method of forming the composition, and a method of treating skin pigmentation are disclosed. The composition comprises at least one pharmaceutically acceptable additive. The composition further comprises at least one melanin production inhibitor, which may be a depigmentation agent. The melanin production inhibitor is present in an amount effective to inhibit melanin production in human skin cells of a subject that is administered the composition. The melanin production inhibitor is selected from the group consisting of cyclovirobuxine D, lipoic acid, nuciferine, peimisine, oleuropein, Rhodiola algida extract, Rhodiola kirilowii (Regel) Maxim extract, Glycyrrhizae Radix et Rhizoma extract, Cirsii japonici herba extract, Platycladi semen extract, Synotis erythropappa extract, Astragali complanati semen extract, Plantaginis semen extract, Lycopi herba extract, Euryales semen extract, Cuscutae semen extract, Amomi fructus extract, Tara seed extract, Platycladi cacumen extract, Eucommiae cortex extract, Dioscoreae rhizoma extract, Cirsii herba extract, and combinations thereof.
A pressure vessel having an outer shell and a flexible inner liner. The outer shell and inner liner are configured so that the water passing through the water treatment system engages the inner liner, and not the outer shell. The inner liner is blow molded from a material that does not leach undesirable substances into the water flowing through the water treatment systems. The inner liner may include a receptacle portion to house one or more water treatment components. The receptacle portion may be flexible under the anticipated range of internal pressures. The receptacle portion may be disposed in the outer shell with the outer shell concealing expansion/contraction of the inner liner and providing the pressure vessel dimensional stability. The inner liner may include a rigid neck portion mounted to the outer shell. The outer shell and/or inner liner may include internal ribs configured to maintain spacing therebetween.
B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
A system and method of detecting coupling between an ultrasound treatment device and human tissue using voltage and/or current feedback mechanism at a singular frequency. The method includes the general steps of: determining the appropriate drive frequency for a transducer, determining the decision boundary for that transducer at the determined drive frequency, applying a drive signal at the determined drive frequency, sensing the current and/or voltage of the drive signal at the determined drive frequency and determining status of coupling based on a comparison of the sensed current and/or voltage with the determined decision boundary. When the decision boundary has been crossed, an alarm may be presented and/or the power may be reduced or eliminated. Current and/or voltage measurements at a secondary drive frequency may be used and compared to a secondary decision boundary to improve accuracy in some applications.
An integrated system for delivering weight loss guidance and activity tracking in a mobile format. The integrated system includes a weight loss program hosted on a mobile device. The weight loss program includes an energy intake prescription to guide a participant toward a target weight according to a weight loss prediction model that is visually depicted in a first application window. The mobile device can be paired with a weight sensor to provide weight updates at regular intervals. The mobile device can also be paired with a caloric expenditure measuring device, for example a step counter, to display activity levels for comparison with recommended activity goals in a second application window. The weight loss program extends over multiple phases that are structured to help individuals gradually achieve a sustainable weight loss while increasing daily activity levels over the duration of the program.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G06F 3/0481 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
G06N 7/00 - Computing arrangements based on specific mathematical models
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
93.
BODY WEIGHT MANAGEMENT AND ACTIVITY TRACKING SYSTEM
An integrated system for delivering weight loss guidance and activity tracking in a mobile format. The integrated system includes a weight loss program hosted on a mobile device. The weight loss program includes an energy intake prescription to guide a participant toward a target weight according to a weight loss prediction model that is visually depicted in a first application window. The mobile device can be paired with a weight sensor to provide weight updates at regular intervals. The mobile device can also be paired with a caloric expenditure measuring device, for example a step counter, to display activity levels for comparison with recommended activity goals in a second application window. The weight loss program extends over multiple phases that are structured to help individuals gradually achieve a sustainable weight loss while increasing daily activity levels over the duration of the program.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
94.
SYSTEM AND METHOD FOR MONITORING INTAKE COMPLIANCE
A product interaction monitor includes sensors for measuring characteristics related to the product and/or product package or other type of container. The product interaction monitor can be installed in a container cap and used to monitor events associated with the container such as product usage. The product interaction monitor can utilize multiple sensor outputs to increase the accuracy of the detection of the events. The product interaction monitor can be used to estimate product inventory or product usage and communicate information regarding the product and/or product usage to a local display or a remote computer.
A product interaction monitor includes sensors for measuring characteristics related to the product and/or product package or other type of container. The product interaction monitor can be installed in a container cap and used to monitor events associated with the container such as product usage. The product interaction monitor can utilize multiple sensor outputs to increase the accuracy of the detection of the events. The product interaction monitor can be used to estimate product inventory or product usage and communicate information regarding the product and/or product usage to a local display or a remote computer.
A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
B65D 51/24 - Closures not otherwise provided for combined with auxiliary devices for non-closing purposes
B65D 41/04 - Threaded or like caps or cap-like covers secured by rotation
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G08B 21/24 - Reminder alarms, e.g. anti-loss alarms
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
A composition and a method for improving the gastrointestinal (Gl) health of a human subject by promoting the activity of amylolytic and short-chain fatty acid (SCFA) producing (e.g. acetogenic and/or butyrogenic) microbes in the Gl system of a human subject. The composition includes a mixture of microbiota accessible carbohydrates (MACs) that includes at least two different resistant starches and at least two different non-starch polysaccharides. A blend for inclusion in a dietary supplement includes, or is, the mixture.
Compositions for suppressing sebum production in skin (e.g., seborrheic skin), and minimizing glycation in skin (e.g., mature skin) with enhanced UV absorptive properties are described. In particular, the present invention relates to a composition containing a skin benefit agent that includes Lithospermum erythrorhizon. Also, methods of suppressing sebum production in skin (e.g., seborrheic skin) and minimizing glycation in skin (e.g., mature skin) by applying a composition to the skin, wherein the composition comprises an effective amount of a derivative of Lithospermum erythrorhizon are also described.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
patents
