Abstract

This invention is in the field of anesthesiology and, in particular, the non-systemic or localized administration of pain medications to traumatized tissue for the treatment of localized pain. The invention provides a composition for use in methods for treating localized pain conditions after surgery. The invention further provides a process of preparing said composition. Furthermore, the invention provides the use of said composition in methods of treating, especially reducing, pain associated with a surgery.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - OintmentsBases therefor
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Abstract

Anastomotic healing, preferably after a surgical anastomosis, is improved by administering to a subject in need thereof a pharmaceutical composition comprising a carboxymethylated starch, a epichlorohydrin-modified starch, or a combination or mixture thereof. A disorder associated with surgical anastomosis, such as impaired bursting pressure, impaired wound healing, impaired growing together of anatomical structures such as intestinal sections, impaired coalescence effects in the joined anatomical structures such as intestinal sections, leakage of the intestine and infection of the intestine can be treated by administration of the aforesaid pharmaceutical composition.

IPC Classes  ?

• A61K 31/718 - Starch or degraded starch, e.g. amylose, amylopectin
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - OintmentsBases therefor

Abstract

The pharmaceutical composition constituted by carboxymethylated starch and citric acid, a citrate, or mixtures thereof, prevents adhesion of injured mesothelial surfaces and the formation of adhesion bands between the mesothelia at the highest level. The composition in gel form acts as a matrix in which connective tissue healing of tissue defects is promoted.

IPC Classes  ?

• A61K 31/718 - Starch or degraded starch, e.g. amylose, amylopectin
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61K 31/194 - Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid

Abstract

According to the invention, a medicament is disclosed, a.) containing carboxymethylated starch and b.) containing a citrate and/or citric acid for reducing post-operative adhesions.

IPC Classes  ?

• A61K 31/718 - Starch or degraded starch, e.g. amylose, amylopectin
• A61K 31/194 - Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
• A61L 31/04 - Macromolecular materials
• A61K 9/06 - OintmentsBases therefor
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Abstract

The invention relates to a medicament which a.) contains or even consists of carboxymethylated starch and/or b.) contains or even consists of epichlorohydrin-modified starch for the treatment of anastomoses.

IPC Classes  ?

• A61K 31/718 - Starch or degraded starch, e.g. amylose, amylopectin
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
• A61K 9/06 - OintmentsBases therefor

Goods & Services

Pharmaceutical preparations; Adhesive bands for medical purposes; Adhesive plaster; Adhesive tapes for medical purposes; Adjuvants for medical purposes; Balms for medical purposes; Bandages for dressings; Biological preparations for medical purposes; Preparations of the treatment of burns; Dressings, medical; Hemostatic pencils; Plaster for medical purposes; Surgical dressings. Medical devices for the treatment of surgical wounds; Surgical implants [artificial materials]; Surgical sponges; sterile surgical sheets. Presentation of goods on communication media for retail purposes; Business research; Publicity.

Goods & Services

Pharmaceutical preparations; Adhesive bands for medical purposes; Adhesive plaster; Adhesive tapes for medical purposes; Adjuvants for medical purposes; Balms for medical purposes; Bandages for dressings; Biological preparations for medical purposes; Biological preparations for veterinary purposes; Preparations of the treatment of burns; Dressings, medical; Plaster for medical purposes; Vulnerary sponges; Surgical dressings. Medical devices for the treatment of surgical wounds; Surgical sponges; Surgical implants [artificial materials]; sterile surgical sheets. Presentation of goods on communication media for retail purposes; Business research; Publicity.