FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
Inventor
Bisgin, Pinar
Renninger, Patrick
Schummer, Christoph Matthias
Abstract
An apparatus for classifying at least one audio signal has an input interface configured to receive input information of the audio signal, a trained first machine-learning-based classifier configured to map the input information to one of a first and a second class of audio signals; a trained second machine-learning-based classifier configured to, if the audio signal belongs to the first class of audio signals, map the input information of the audio signal belonging to the first class of audio signals to one of a plurality of third classes of audio signals, and an output interface configured to output information on which classes the audio signal belongs to.
A compound of formula (I), (IA) or formula (II) or a composition comprising the compound of formula (I), (IA) or formula (II) in association with a veterinarily acceptable carrier are described. A method of controlling helminths using same is described.
This invention provides for compounds of the formula:
This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing educational services, namely a program to provide
long-term on-farm training and courses in the field of swine
health; organizing and conducting of workshops, seminars and
training courses for veterinary care and animal-health
management, including online and via the Internet in the
field of swine health. Providing online information on diagnosis, prophylaxis and
therapies of pig diseases, via a global communication
network.
6.
ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREVENTION OF SYSTEMIC DISEASES IN CATS
A method is described for the prophylaxis of hypertension in a cat in need thereof. The method includes administration of an effective amount of angiotensin II receptor 1 (AT-1) antagonist (sartan) to the cat, wherein the prophylaxis of hypertension is a delay of onset of hypertension.
A method is described for the prophylaxis of hypertension in a cat in need thereof. The method includes administration of an effective amount of angiotensin II receptor 1 (AT-1) antagonist (sartan) to the cat, wherein the prophylaxis of hypertension is a delay of onset of hypertension.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Medical and scientific research in the field of prevention and treatment of metabolic disease in horses; Providing medical and scientific research information
The present invention relates to a method of optically inspecting bottles comprising producing one or more digital representations by optically sensing one of the bottles, and automatically analyzing the one or more digital representations for identifying anomalies, wherein the optically sensing comprises optically sensing an external appearance of the one of the bottles, preferably while the uptake volume is empty, such that at least one of the analyzed digital representations characterizes the external appearance, and wherein the optically sensing comprises optically sensing an internal appearance at least of a bottom of the one of the bottles through the opening while the uptake volume is empty such that at least one of the analyzed digital representations characterizes the internal appearance of the bottom. Further, the present invention relates to a system and a computer program as well as a computer-readable medium for performing the method.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
administration of a program for enabling participants to obtain discounts on animal health products and services; providing advertising, marketing and promotional services, namely, development of promotional advertising campaigns for web pages for a discount program for animal health products providing a website featuring information in the field of animal health products and veterinary services
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Providing educational services, namely a program to provide long-term on-farm training and courses in the field of swine health; organizing and conducting of workshops, seminars and training courses for veterinary care and animal-health management, including online and via the Internet in the field of swine health.
(2) Providing online information on diagnosis, prophylaxis and therapies of pig diseases, via a global communication network.
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing educational services, namely a program to provide long-term on-farm training and courses in the field of swine health; organizing and conducting of workshops, seminars and training courses for veterinary care and animal-health management, including online and via the Internet in the field of swine health. Providing online information on diagnosis, prophylaxis and therapies of pig diseases, via a global communication network.
09 - Scientific and electric apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded computer software for sharing of data and information in the field of animal health Education services, namely, providing training programs and courses in the field of animal health Providing temporary use of on-line non-downloadable software and applications for sharing of data and information in the field of animal health
The present invention relates to a method for structure elucidation of the structure of an unknown chemical compound from a measured spectrum of a sample. The method includes at least one machine learning model, in particular a first machine learning model that generates structures of chemical compounds and/or a second machine learning model that generates predicted spectra from the structures.
The present invention provides recombinant herpes virus of turkeys (HVT) viral vectors comprising a heterologous polynucleotide encoding an avian influenza antigen. The recombinant viral vectors are suitable for use in immunogenic compositions and vaccines, and can provide protection against avian influenza and other pathogens when administered to an avian.
The present invention provides recombinant Newcastle disease virus (NDV) viral vectors comprising a heterologous polynucleotide encoding an avian influenza antigen. The recombinant viral vectors are suitable for use in immunogenic compositions and vaccines, and can provide protection against avian influenza and other pathogens when administered to an avian.
The present invention provides recombinant canine distemper virus (CDV) viral vectors comprising a heterologous polynucleotide encoding an avian influenza antigen. The recombinant viral vectors are suitable for use in immunogenic compositions and vaccines, and can provide protection against avian influenza and other pathogens when administered to an animal.
The present invention relates i.a. to an IBV (infectious bronchitis virus) encoding for a heterologous DMV S (spike) protein or fragment thereof. Further, the present invention relates to an immunogenic composition comprising said IBV encoding for a heterologous DMV S (spike) protein or fragment thereof. Furthermore, the present invention relates to methods for immunizing a subject comprising administering to such subject the immunogenic composition of the present invention. Moreover, the present invention relates to methods of treating or preventing clinical signs caused by IBV in a subject of need, the method comprising administering to the subject a therapeutically effective amount of an immunogenic composition according to the present invention.
The present invention relates i.a. to an IBV (infectious bronchitis virus) encoding for a heterologous DMV S (spike) protein or fragment thereof. Further, the present invention relates to an immunogenic composition comprising said IBV encoding for a heterologous DMV S (spike) protein or fragment thereof. Furthermore, the present invention relates to methods for immunizing a subject comprising administering to such subject the immunogenic composition of the present invention. Moreover, the present invention relates to methods of treating or preventing clinical signs caused by IBV in a subject of need, the method comprising administering to the subject a therapeutically effective amount of an immunogenic composition according to the present invention.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations for pets for the treatment of hypertension; veterinary preparations for pets for the treatment of chronic kidney disease; veterinary preparations for pets for the treatment of diseases and disorders of the alimentary tract and metabolism; veterinary preparations for the treatment of diseases and disorders of the cardiovascular system.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Interactive databases containing information in the field of
parasites in pets; computer applications and internet-based
applications in the field of parasites in pets; software and
software applications for mobile devices in the field of
parasites in pets. Providing medical and scientific research information in the
field of parasites in pets. Veterinary services provided via mobile application software
in the field of parasites in pets.
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof for the prophylaxis and/or treatment of one or more cardiac diseases in a non-human mammal/non-human mammal patient excluding a feline, in particular a canine/canine patient.
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Interactive databases containing information in the field of parasites in pets; computer applications and internet-based applications in the field of parasites in pets; software and software applications for mobile devices in the field of parasites in pets providing medical and scientific research information in the field of parasites in pets (1) Providing medical and scientific research information in the field of parasites in pets
(2) Veterinary services provided via mobile application software in the field of parasites in pet animals
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Interactive databases containing information in the field of parasites in pets; computer applications and internet-based applications in the field of parasites in pets; software and software applications for mobile devices in the field of parasites in pets providing medical and scientific research information in the field of parasites in pets (1) Providing medical and scientific research information in the field of parasites in pets
(2) Veterinary services provided via mobile application software in the field of parasites in pet animals
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary vaccines
31.
COMBINATION TREATMENT AND/OR PREVENTION OF RENAL DISEASES AND/OR HYPERTENSION IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND TELMISARTAN
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof in combination with telmisartan or pharmaceutically acceptable forms thereof, in particular for the prophylaxis and/or treatment of one or more renal diseases and/or hypertension in a non-human mammal / non-human mammal patient, such as a dog or a cat.
A61K 31/382 - Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
32.
COMBINATION TREATMENT AND/OR PREVENTION OF CARDIAC DISEASES IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND PIMOBENDAN AND/OR TELMISARTAN
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof in combination with pimobendan and/or telmisartan or pharmaceutically acceptable forms thereof, in particular for the prophylaxis and/or treatment of one or more cardiac diseases in a non-human mammal/non-human mammal patient, such as a dog or a cat.
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
33.
Combination treatment and/or prevention of renal diseases and/or hypertension in non-human mammals comprising one or more SGLT-2 inhibitors and telmisartan
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof in combination with telmisartan or pharmaceutically acceptable forms thereof, in particular for the prophylaxis and/or treatment of one or more renal diseases and/or hypertension in a non-human mammal/non-human mammal patient, such as a dog or a cat.
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
34.
COMBINATION TREATMENT AND/OR PREVENTION OF CARDIAC DISEASES IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND PIMOBENDAN AND/OR TELMISARTAN
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof in combination with pimobendan and/or telmisartan or pharmaceutically acceptable forms thereof, in particular for the prophylaxis and/or treatment of one or more cardiac diseases in a non-human mammal / non-human mammal patient, such as a dog or a cat.
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61K 31/382 - Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary preparations, for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations, for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations, for the prevention and the treatment of oncological diseases; veterinary preparations, for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic products for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary preparations, for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations, for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations, for the prevention and the treatment of oncological diseases; veterinary preparations, for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic products for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations for the prevention and the treatment of oncological diseases; veterinary preparations for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic preparations for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations for the prevention and the treatment of oncological diseases; veterinary preparations for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations namely, anti-parasitic preparations for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary preparations, for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations, for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations, for the prevention and the treatment of oncological diseases; veterinary preparations, for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic products for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary preparations, for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations, for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations, for the prevention and the treatment of oncological diseases; veterinary preparations, for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic products for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations for the prevention and the treatment of oncological diseases; veterinary preparations for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic preparations for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations for the prevention and the treatment of metabolic diseases disorders; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damages and injuries; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; vaccines for veterinary use; sedatives for veterinary use; stem cells for veterinary use; surgical implants comprising living tissue and grown from stem cells for veterinary use; dietary and nutritional supplements for animals; dietetic animal foodstuffs for medical purposes; veterinary preparations for the prevention and the treatment of endocrine disorders and diseases; veterinary preparations for the prevention and treatment of skin diseases; veterinary preparations for the prevention and the treatment of oncological diseases; veterinary preparations for the prevention and the treatment of gastrointestinal diseases; veterinary preparations for dental purposes; medicated mouth care preparations for animals; veterinary preparations, namely, anti-parasitic preparations for veterinary use; veterinary preparations for the prevention and treatment of ophthalmic diseases and disorders
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Interactive databases containing information in the field of parasites in pets; computer applications and internet-based applications in the field of parasites in pets; software and software applications for mobile devices in the field of parasites in pets. (1) Providing medical and scientific research information in the field of parasites in pets.
(2) Veterinary services provided via mobile application software in the field of parasites in pets.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Interactive databases, recorded, namely, interactive digital risk checker tool containing information in the field of parasites in pets; recorded computer applications for pet owners to evaluate the risk factors in the field of parasites in pets via the internet; downloadable software and software applications for mobile devices for pet owners to evaluate the risk factors in the field of parasites in pets Providing medical and scientific research information in the field of parasites in pets. Veterinary services provided via mobile application software in the field of parasites in pets.
45.
IMMUNOGENIC COMPOSITION USEFUL FOR SELF-ADMINISTRATION BY PIGS
The present invention relates to immunogenic compositions comprising (i) an antigen composition which comprises or consists of a virus antigen and (ii) a gel composition comprising a flavoring agent, wherein such immunogenic composition can be placed into the housing environment of livestock, in particular of pigs. Thereby the self-administration of the immunogenic composition by the pigs is enabled, which allows to simply induce an immune response in the animals, by a minimum workload for personnel and less stress for the pigs.
The present invention relates to methods for inducing an immune response in a subject, the method comprising administering orally to the subject an immunogenic composition comprising non-replicating virus antigen. In one example, an immunogenic composition is administered via the oral route to a pig, wherein the immunogenic composition comprises a recombinant virus capsid protein capable of forming a virus-like particle. This allows to simply induce an immune response in the pigs, while simultaneously reducing the propensity for adverse reactions, eliminating the risk of injection site reactions, avoiding pain, and putting less stress on the animals.
(1) Aliments pour les animaux et additifs pour fourrages non à usage médical.
48.
CRYSTALLINE COMPLEXES BETWEEN VELAGLIFLOZIN AND SELECTED CO-CRYSTAL FORMING AGENTS, METHODS FOR THEIR PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
The invention relates to crystalline complexes of velagliflozin and selected co-crystal forming agents, to methods for their preparation as well as to the use thereof for preparing medicaments.
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
An optical system having a chamber for receiving an element of body fluid or tissue or environmental sample to be characterized has a light source for illuminating the chamber with light, and a spectrometer for recording a spectrum of light originating from the chamber. The light source has two separate LEDs to emit light having at least two spectral maxima of different wavelength ranges. The light from the light source is directed to the chamber. A method for determining a parameter representing a property of the element with the optical system, wherein, light having at least two spectral maxima of different wavelength ranges generated by separate LEDs is directed onto the element, a spectrum with reflected components of the light, scattered components of the light, and/or light caused by Raman scattering or fluorescence of the element is measured with the spectrometer, and the parameter is determined by evaluating the spectrum.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/33 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
G01N 21/359 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
G01N 33/487 - Physical analysis of biological material of liquid biological material
The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulfoximine-pyridine derivatives of formulae (I), (Ia) or (Ib)
The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulfoximine-pyridine derivatives of formulae (I), (Ia) or (Ib)
The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulfoximine-pyridine derivatives of formulae (I), (Ia) or (Ib)
wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as crop protection agents.
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
A method for calibrating an optical system that has a chamber for receiving an element of body fluid or tissue or environmental sample uses a light source for illuminating the chamber with light, and a spectrometer for measuring a spectrum of light originating from the chamber, wherein the brightness of the light source is controlled while measuring a spectrum for calibration with the spectrometer so that the brightness of the light source is a reduced brightness, a brightness reduced relative to a nominal brightness of the light source, and/or a brightness reduced relative to a brightness of the light source when measuring the spectrum of the element; and/or wherein a spectrometer of the optical system is monitored with regard to a changed measurement behavior and upon detection of the changed measurement behavior of the spectrometer a calibration. Preferably spectra of preceding measurements are compared with each other.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
The present invention relates to N-oxide compounds of formula (I) or formula (Ia) or formula (Ib)
The present invention relates to N-oxide compounds of formula (I) or formula (Ia) or formula (Ib)
The present invention relates to N-oxide compounds of formula (I) or formula (Ia) or formula (Ib)
wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as crop protection agents.
A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
Systems and methods are described for treatment and/or prevention of a metabolic disorder and/or another medical condition in a patient (e.g., a feline) by administering to the patient a liquid pharmaceutical composition, preferably including one or more SGLT-2 inhibitor compound(s), via a delivery system that includes a syringe. The syringe includes features that facilitate easy, safe and effective doses of small volumetric amounts of the liquid pharmaceutical composition to the patient during administration.
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
54.
USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF RENAL DISEASES IN NON-HUMAN MAMMALS
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof for the prophylaxis and/or treatment of one or more renal diseases in a non-human mammal, such as a carnivore, in particular a cat or a dog.
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
A61K 31/382 - Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
55.
SYSTEMS FOR DELIVERY OF LIQUID PHARMACEUTICAL COMPOSITIONS IN PARTICULAR COMPRISING ONE OR MORE SGLT-2 INHIBITOR(S)
Systems and methods are described for treatment and/or prevention of a metabolic disorder and/or another medical condition in a patient (e.g., a feline) by administering to the patient a liquid pharmaceutical composition, preferably including one or more SGLT-2 inhibitor compound(s), via a delivery system that includes a syringe. The syringe includes features that facilitate easy, safe and effective doses of small volumetric amounts of the liquid pharmaceutical composition to the patient during administration.
C07H 15/203 - Monocyclic carbocyclic rings other than cyclohexane ringsBicyclic carbocyclic ring systems
C07H 17/00 - Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
C07H 17/02 - Heterocyclic radicals containing only nitrogen as ring hetero atoms
C07H 19/01 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radicalNucleosidesMononucleotidesAnhydro derivatives thereof sharing oxygen
The present invention relates to tetrazole substituted ethylsulfone/sulfoximine-pyridine derivatives of formula (I), (Ia) or (Ib)
The present invention relates to tetrazole substituted ethylsulfone/sulfoximine-pyridine derivatives of formula (I), (Ia) or (Ib)
wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as as crop protection agents.
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
The present invention relates to tetrazole substituted ethylsulfone/sulfoximine-pyridine derivatives of formula (I), (Ia) or (Ib) wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as as crop protection agents.
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
A01N 43/713 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulfoximine-pyridine derivatives of formulae (I), (la) or (lb) wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as as crop protection agents.
A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
A01N 43/80 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
A01N 43/82 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with three hetero atoms
C07D 253/07 - 1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 417/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/438 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring being spiro-condensed with carbocyclic or heterocyclic ring systems
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
The present invention relates to N-oxide compounds of formula (I) or formula (Ia) or formula (Ib) wherein the variables are as defined in the description and/or in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in/on animals as well as as crop protection agents.
C07D 237/26 - Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
C07D 221/02 - Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups condensed with carbocyclic rings or ring systems
A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
A01N 43/80 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
A01N 43/82 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with three hetero atoms
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
A61K 31/438 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring being spiro-condensed with carbocyclic or heterocyclic ring systems
62.
USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF HYPERTENSION IN NON-HUMAN MAMMALS
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof for the prophylaxis and/or treatment of hypertension in a non-human mammal, preferably a carnivore, in particular a cat or a dog.
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Recombinant viral vectors and compositions that include them for use as vehicles to induce an immunological response. Multivalent viral vectors may be used in compositions or vaccines containing one or more recombinant viral vectors for protection against a variety of pathogens. Formation of these viral vectors may include insertion and expression of foreign genes to protect against a variety of pathogens. Further provided are methods of making and using the recombinant viral vectors, as well as immunogenic compositions that include the vectors and/or antigens. In particular, immunogenic compositions may include recombinant viral vectors such as vHVT509, vHVT522, and/or vHVT523.
This invention provides for compounds of the formula:
This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and methods for the treatment, control and/or prevention of a parasitic infestation and/or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
C07D 491/052 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
A method and system for measuring a liquid level within a cold storage container and/or determining its cooling capacity based on the liquid level includes a sensor column. The sensor column has a plurality of resistive temperature detectors (RTDs) positioned along its length. A central controller is coupled to the plurality of RTDs. A cold storage container receives the sensor column, wherein the central controller may determine a liquid level of a cryogenic liquid held within the cold storage container using the RTDs. And based on the liquid level determined, the central controller determines a remaining cooling capacity of the cold storage container as the cryogenic liquid evaporates / changes phase over time. The central controller may also detect other conditions of the container, such as, but not limited to, a tilt position, an opened state, and/or presence of the container on a moving vehicle.
G01F 23/24 - Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring variations of resistance of resistors due to contact with conductor fluid
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific research in the field of veterinary medicine; providing medical and scientific research information in the field of veterinary pharmaceuticals
42 - Scientific, technological and industrial services, research and design
Goods & Services
Scientific research in the field of veterinary medicine; providing medical and scientific research information in the field of veterinary pharmaceuticals..
The invention relates to novel solid dispersions comprising amorphous pimobendan and one or more stabilizing polymers as well as processes of manufacturing thereof and corresponding pharmaceutical compositions.
The invention relates to novel solid dispersions comprising amorphous pimobendan and one or more stabilizing polymers as well as processes of manufacturing thereof and corresponding pharmaceutical compositions.
This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
Streptococcus infections in pigs. The invention provides a ΔFolT mutant of a bacterium having reduced capacity to transport folate, wherein said capacity has been reduced by functionally deleting folate transporter (FolT) function. The invention also provides a method to reduce virulence of a bacterium comprising reducing the capacity of said bacterium to transport folate.
C07K 14/315 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
A61K 39/00 - Medicinal preparations containing antigens or antibodies
76.
ADMINISTRATION PACKAGING, PRODUCTION APPARATUS AND PRODUCTION METHOD
An administration packaging for a pharmaceutical product as well as an apparatus and a method for producing and filling such administration packaging in which a predetermined breaking zone for opening the administration packaging by breaking is generated by thermoforming. For this purpose, the apparatus has a molding tool with a forming device for forming the predetermined breaking zone. Alternatively, or in addition, the predetermined breaking zone may form a cross-section reduction or nozzle of an administration channel of the administration packaging. Alternatively, or in addition, the predetermined breaking zone may only extend over the administration channel, but not over a rim of the administration packaging. Alternatively, or in addition, the predetermined breaking zone may be formed as a kink.
An administration packaging (1A, 1) for a pharmaceutical product (2) is proposed as well as an apparatus and a method for producing and filling such administration packaging (1A, 1). A predetermined breaking zone (10, 9) for opening the administration packaging (1A, 1) by breaking the breaking zone (10, 9) is generated by thermoforming. For this purpose, the apparatus comprises a molding tool (102A, 102) with a forming device for forming the predetermined breaking zone (10, 9). Alternatively or in addition, the predetermined breaking zone (10, 9) may form a cross-section reduction or nozzle (19) of an administration channel (7A, 7) of the administration packaging (1A, 1).
B29C 65/14 - Joining of preformed partsApparatus therefor by heating, with or without pressure using wave energy or particle radiation
B29C 65/72 - Joining of preformed partsApparatus therefor by combined operations, e.g. welding and stitching
B29C 65/00 - Joining of preformed partsApparatus therefor
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 9/04 - Enclosing successive articles, or quantities of material, between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
B65B 51/14 - Applying or generating heat or pressure or combinations thereof by reciprocating or oscillating members
B65D 75/52 - Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers Details
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
B29C 51/10 - Forming by pressure difference, e.g. vacuum
B29C 51/14 - Shaping by thermoforming, e.g. shaping sheets in matched moulds or by deep-drawingApparatus therefor using multilayered preforms or sheets
B29C 51/44 - Removing or ejecting moulded articles
B29C 65/18 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool
The invention relates to an administration packaging and method for its production. The administration packaging comprises a bottom part and a cover which are obtained from multi-layer films.
B32B 3/30 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
B32B 7/05 - Interconnection of layers the layers not being connected over the whole surface, e.g. discontinuous connection or patterned connection
B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Germany)
Inventor
Bisgin, Pinar
Renninger, Patrick
Schummer, Christoph Matthias
Abstract
The present disclosure relates to an apparatus (10) for classifying at least one audio signal (20). The apparatus (10) comprises an input interface (12) configured to receive input information (22) of the audio signal (20), a trained first machine-learning-based classifier (16) configured to map the input information (22) to one of a first and a second class of audio signals (24; 26); a trained second machine-learning-based classifier (18) configured to, if the audio signal (20) belongs to the first class of audio signals (24), map the input information (22) of the audio signal belonging to the first class of audio signals (24) to one of a plurality of third classes (28) of audio signals, and an output interface configured to output information on which classes the audio signal (20) belongs to.
G10L 25/30 - Speech or voice analysis techniques not restricted to a single one of groups characterised by the analysis technique using neural networks
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
80.
ADMINISTRATION PACKAGING, PRODUCTION APPARATUS AND PRODUCTION METHOD
B29C 51/08 - Deep-drawing or matched-mould forming, i.e. using mechanical means only
B29C 51/10 - Forming by pressure difference, e.g. vacuum
B29C 51/14 - Shaping by thermoforming, e.g. shaping sheets in matched moulds or by deep-drawingApparatus therefor using multilayered preforms or sheets
B29C 51/26 - Component parts, details or accessoriesAuxiliary operations
B65B 3/02 - Machines characterised by the incorporation of means for making the containers or receptacles
B65B 9/04 - Enclosing successive articles, or quantities of material, between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
B65B 51/14 - Applying or generating heat or pressure or combinations thereof by reciprocating or oscillating members
B65D 75/52 - Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers Details
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
81.
Administration packaging and method for its production
An administration packaging and method for its production. The administration packaging having a bottom part and a cover which are formed of multi-layer films.
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
B32B 7/02 - Physical, chemical or physicochemical properties
B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/02 - Machines characterised by the incorporation of means for making the containers or receptacles
B65D 75/32 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
interactive databases containing information in the field of parasites in pets; computer applications and internet-based applications in the field of parasites in pets; software and software applications for mobile devices in the field of parasites in pets. providing medical and scientific research information in the field of parasites in pets. veterinary services provided via mobile application software in the field of parasites in pets.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Veterinary preparations, for the prevention and the treatment of metabolic diseases; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damage and injuries; veterinary preparations for the prevention and the treatment of hormonal diseases and disorders; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the prevention and the treatment of parasites; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; veterinary vaccines; sedatives for animals; veterinary preparations, namely, stem cells for veterinary use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Veterinary preparations, for the prevention and the treatment of metabolic diseases; veterinary preparations for the prevention and the treatment of cardiovascular diseases; veterinary preparations for the prevention and the treatment of neurological diseases and disorders; veterinary preparations for the prevention and the treatment of musculoskeletal diseases and disorders; veterinary preparations for the prevention and treatment of tendon and muscle damage and injuries; veterinary preparations for the prevention and the treatment of hormonal diseases and disorders; veterinary preparations against bacterial infections, namely, antibiotics, anti-infectives; veterinary preparations for the prevention and the treatment of respiratory diseases; veterinary preparations for the prevention and the treatment of parasites; veterinary preparations for the treatment of inflammatory diseases; veterinary preparations for udder care; veterinary vaccines; sedatives for animals; veterinary preparations, namely, stem cells for veterinary use.
85.
USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREAT-MENT OF CARDIAC DISEASES IN FELINES
The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof for the prophylaxis and/or treatment of one or more cardiac diseases in feline animals.
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61K 31/4422 - 1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61K 31/554 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and at least one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
A61K 31/585 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
A61K 31/616 - Salicylic acidDerivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
The current invention relates to mesenchymal stem cells (MSCs) or a pharmaceutical composition comprising an effective amount of MSCs for use in the treatment of insect-bite hypersensitivity (IBH) in equines.
The disclosure relates to the field of medicine, in particular to the field of veterinary medicine. The disclosure relates to a pharmaceutical (medicament) formulation of glucocorticoids, especially ciclesonide or a pharmaceutically acceptable derivative thereof.
A61P 11/00 - Drugs for disorders of the respiratory system
A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Education and providing of training in the veterinary field
related to diabetes in pets; preparation and running of
congresses and seminars in the veterinary field for
educational purposes. Providing of medical and scientific research information in
the veterinary field related to diabetes in pets.
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
The invention relates to novel aqueous pharmaceutical compositions comprising at least one SGLT-2 inhibitor and one or more solubilizing agents as well as corresponding processes of manufacturing such aqueous pharmaceutical compositions and their medical uses.
A61K 31/7004 - Monosaccharides having only carbon, hydrogen and oxygen atoms
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 47/46 - Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
The invention relates to novel aqueous pharmaceutical compositions comprising at least one SGLT-2 inhibitor and one or more solubilizing agents as well as corresponding processes of manufacturing such aqueous pharmaceutical compositions and their medical uses.
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
The invention relates to a liquid applicator, for administering liquids, including vaccines, to animals. In particular, the applicator is useful for delivering liquids to mouths of animals.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Education and providing of training in the veterinary field related to diabetes in pets; preparation and running of congresses and seminars in the veterinary field for educational purposes.
(2) Providing of medical and scientific research information in the veterinary field related to diabetes in pets.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing educational courses and training in the veterinary field related to diabetes in pets; preparation and running of congresses and seminars in the veterinary field for educational purposes Providing of medical and scientific research information in the veterinary field related to diabetes in pets
96.
USE OF SGLT-2 INHIBITORS IN THE DRYING-OFF OF NON-HUMAN MAMMALS
The present invention is directed to the use of at least one SGLT-2 inhibitor in a non-human mammal, preferably ruminant, preferably for drying-off of a non-human mammal, preferably ruminant, as well as corresponding methods, such as improving and/or facilitating the drying-off of a non-human mammal, preferably ruminant, comprising administering to such non-human mammal, preferably ruminant, at least one SGLT-2 inhibitor.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A23K 20/24 - Compounds of alkaline earth metals, e.g. magnesium
A23K 20/121 - Heterocyclic compounds containing oxygen or sulfur as hetero atom
A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
A61K 31/382 - Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
A61K 31/7028 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
A61K 31/7034 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
A61K 31/7042 - Compounds having saccharide radicals and heterocyclic rings
97.
Modified S1 subunit of the coronavirus spike protein
The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
