Apparatus and methods for cleaning a single-port fluidic device, such as a single-port, diaphragm-based cardiac pump, with a continuous stream of fresh cleaning fluid, while simultaneously draining soiled fluid, via a single input-output port of the fluidic device. A first coupler releasably mates with the input-output port. The first coupler includes an injector nozzle and a return port. The injector nozzle is oriented to direct a stream of pressurized cleaning fluid toward an interior chamber of the single-port fluidic device. The return port simultaneously removes soiled cleaning fluid from the interior chamber. A circulation pump delivers the pressurized cleaning fluid from a tank to the injector nozzle, and returns soiled cleaning fluid from the return port to the tank, via a cleaning fluid circulation circuit. Optionally, the diaphragm may be alternately driven between two positions, to agitate the cleaning fluid within the interior chamber, thereby enhancing cleaning efficiency.
B08B 9/032 - Cleaning the internal surfacesRemoval of blockages by the mechanical action of a moving fluid, e.g. by flushing
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/268 - Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
B08B 13/00 - Accessories or details of general applicability for machines or apparatus for cleaning
F04B 43/02 - Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
A blood pump may be provided. The blood pump may include a blood flow section operably coupled to a distal end of a catheter. The blood flow section may be configured to cause blood to flow into a blood flow inlet of the blood flow section, through the blood flow section, and out of a blood flow outlet. At least one external and/or internal surface of the blood flow section may include at least a portion of a surface modified by one or more fluorinated end groups and/or silicone end groups of an oligomer or copolymer. The surface may be modified by one or more fluorinated end groups of an oligomer. The surface may be modified by one or more silicone end groups of a copolymer. The oligomer or copolymer may include a silicone, a polycarbonate, a polyurethane, a polyamide, a polyethylene, a polypropylene, a polysulfone, or a polyvinyl chloride.
Methods and apparatus for providing sensory feedback to an operator of a mechanical circulatory support (MCS) device are provided. The method comprises monitoring, using a controller of the MCS device, one or more physiological signals associated with a heart of a patient within which the MCS device is placed, generating an alert signal based, at least in part, on the monitored one or more physiological signals, and transmitting in response to generating the alert signal, a control signal from the controller of the MCS to a feedback device, wherein the feedback device is configured to provide sensory feedback to an operator of the MCS device based on the control signal.
A blood pump may be provided. The blood pump may include a blood flow section operably coupled to a distal end of a catheter. The blood flow section may be configured to cause blood to flow into a blood flow inlet of the blood flow section, through the blood flow section, and out of a blood flow outlet. At least one external and/or internal surface of the blood flow section may include at least a portion of a surface modified by one or more fluorinated end groups and/or silicone end groups of an oligomer or copolymer. The surface may be modified by one or more fluorinated end groups of an oligomer. The surface may be modified by one or more silicone end groups of a copolymer. The oligomer or copolymer may include a silicone, a polycarbonate, a polyurethane, a polyamide, a polyethylene, a polypropylene, a polysulfone, or a polyvinyl chloride.
A61M 60/90 - Details not provided for in groups , or
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A catheter may be provided. The catheter may include an expandable occlusion element coupled to an external surface of a tubular body at a proximal end of the expandable occlusion element and a distal end of the expandable occlusion element. An inner surface of the expandable occlusion element may define a volume of space between the inner surface of the expandable occlusion element and an external surface of the tubular body. The catheter may include a plurality of lumens. A first lumen may be configured to allow a first fluid to be introduced and/or removed from the volume of space defined by the inner surface of the expandable occlusion element. A second lumen may be configured to receive a pressure sensor or define a fluid-filled pressure transducer. A third lumen may be configured to allow a second fluid to be removed from the volume of space.
Methods and apparatus for controlling a heart pump system are described. The heart pump system includes a first heart pump and a second heart pump and a controller. The controller includes a data interface configured to receive first data from the first heart pump and second data from the second heart pump, and at least one computer processor. The at least one computer process is programmed to display in a first portion of a user interface, an indication of the first data, display in a second portion of the user interface, an indication of the second data, and control an operation of the first heart pump and/or the second heart pump.
A61M 60/183 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices drawing blood from both ventricles, e.g. bi-ventricular assist devices [BiVAD]
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A bilateral mechanical circulatory support system is described. The bilateral mechanical circulatory support system includes a first heart pump configured to be positioned across an aortic valve of a patient, the first heart pump including a first pressure sensor and a second pressure sensor, a second heart pump configured to be positioned across a pulmonary valve of the patient, the second heart pump including a third pressure sensor and a fourth pressure sensor, and at least one controller. The at least one controller is configured to control operation of the first heart pump and the second heart pump, the at least one controller configured to receive pressure signals from the first pressure sensor, the second pressure sensor, the third pressure sensor, and the fourth pressure sensor. The system further includes a display configured to display one or more waveforms or values based, at least in part, on the pressure signals.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/183 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices drawing blood from both ventricles, e.g. bi-ventricular assist devices [BiVAD]
A61M 60/196 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body replacing the entire heart, e.g. total artificial hearts [TAH]
A61M 60/221 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having both radial and axial components, e.g. mixed flow pumps
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/816 - Sensors arranged on or in the housing, e.g. ultrasound flow sensors
Various devices, systems, and techniques are provided for purging blood pumps. A purge apparatus may be provided that may include a housing having a hinged lid defining a first surface of the housing. The hinged lid may be configured to allow access to an internal volume of space of the housing. The housing may have an opening on a second surface opposite the first surface. The housing may define a tubing channel configured to receive at least a portion of a tube. The purge apparatus may include a pumping mechanism configured to be operably coupled to a motor through the opening. The pumping mechanism may be disposed within the internal volume of space of the housing. The pumping mechanism may be configured to, during operation, compress the tube extending through the purge apparatus so as to continuously maintain a positive pressure downstream of the pumping mechanism.
A console associated with a medical device is provided. The console includes a user interface, a visual indicator separate from the user interface, and a controller. The controller is configured to control an operation of the medical device, receive data from the medical device, display an indication of the data on the user interface, and change an output of the visual indicator based, at least in part, on the data.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 60/00 - Blood pumpsDevices for mechanical circulatory actuationBalloon pumps for circulatory assistance
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A dual-band phosphor-converted light emitting diode (PC-LED) is provided. The dual-band PC-LED includes a blue LED configured to generate blue light, a first phosphor-based light filter configured to output visible light based on the blue light; and a second phosphor-based light filter configured to output near-infrared light based on the visible light.
G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis
A plug for a blood pump may be provided. The plug may include a housing. A central optical ferrule, coaxial with a central axis of the housing, may extend partially through the housing. A first end of the central optical ferrule may be an axial distance from an outer surface at a first end of the housing. The plug may include a plurality of electrical pins, each pin disposed parallel to the central axis and independently at a radial distance from the central axis. Each electrical pin may have an end extending through the housing and extending beyond the first end of the central optical ferrule. The plug may include additional optical ferrule(s) extending at least partially though the housing. Each additional ferrule being parallel to the central axis and disposed at a radial distance from the central axis.
Disclosed are devices and systems utilizing specifically designed catheters. The catheters may include a tubular body having a first end and a second end. The tubular body may have an outer diameter that is no more than 9 Fr. The tubular body may define a plurality of lumen extending at least partially through the catheter (e.g, from the first end towards the second end). A first lumen may be configured to slidably receive a guidewire. A second lumen may be configured to inflate and/or deflate a first expandable occlusion element. A third lumen may be configured to inflate and/or deflate a second expandable occlusion element. The catheter may include a plurality of additional lumen.
An inflation cartridge may be provided. The cartridge may include a first and second syringe. The cartridge may include external housing defining an internal volume of space. The external housing may have at least one opening configured to allow access to an end of the first syringe and the second syringe. The housing may include a first port couplable to an expandable occlusion device. The housing may include a second port couplable to an external fluid source. The cartridge may include a plurality of valves operably coupled to the first syringe and the second syringe, the first port, and the second port.
A plug for a blood pump may be provided. The plug may include a housing. A central optical ferrule, coaxial with a central axis of the housing, may extend partially through the housing. A first end of the central optical ferrule may be an axial distance from an outer surface at a first end of the housing. The plug may include a plurality of electrical pins, each pin disposed parallel to the central axis and independently at a radial distance from the central axis. Each electrical pin may have an end extending through the housing and extending beyond the first end of the central optical ferrule. The plug may include additional optical ferrule(s) extending at least partially though the housing. Each additional ferrule being parallel to the central axis and disposed at a radial distance from the central axis.
An optical assembly for placement on a medical device. The optical assembly has a diaphragm suspended on and over an optical cavity. The optical cavity has a sensor dot formed thereon. The diaphragm is covered with a biocompatible platinum silicide layer.
Methods and apparatus for controlling a heart pump system are described. The heart pump system includes a first heart pump and a second heart pump and a controller. The controller includes a data interface configured to receive first data from the first heart pump and second data from the second heart pump, and at least one computer processor. The at least one computer process is programmed to display in a first portion of a user interface, an indication of the first data, display in a second portion of the user interface, an indication of the second data, and control an operation of the first heart pump and/or the second heart pump.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/546 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood flow, e.g. by adapting rotor speed
A61M 60/554 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
A bilateral mechanical circulatory support system is described. The bilateral mechanical circulatory support system includes a first heart pump configured to be positioned across an aortic valve of a patient, the first heart pump including a first pressure sensor and a second pressure sensor, a second heart pump configured to be positioned across a pulmonary valve of the patient, the second heart pump including a third pressure sensor and a fourth pressure sensor, and at least one controller. The at least one controller is configured to control operation of the first heart pump and the second heart pump, the at least one controller configured to receive pressure signals from the first pressure sensor, the second pressure sensor, the third pressure sensor, and the fourth pressure sensor. The system further includes a display configured to display one or more waveforms or values based, at least in part, on the pressure signals.
A61M 60/157 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel mechanically acting upon the inside of the patient’s blood vessel structure, e.g. contractile structures placed inside a vessel
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/47 - Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
An inflation cartridge may be provided. The cartridge may include a first and second syringe. The cartridge may include external housing defining an internal volume of space. The external housing may have at least one opening configured to allow access to an end of the first syringe and the second syringe. The housing may include a first port couplable to an expandable occlusion device. The housing may include a second port couplable to an external fluid source. The cartridge may include a plurality of valves operably coupled to the first syringe and the second syringe, the first port, and the second port.
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
A61M 60/497 - Details relating to driving for balloon pumps for circulatory assistance
19.
INTRACARDIAC BLOOD PUMP WITH CAPACITIVE SENSING LOCATION DETECTION
Methods and apparatus for determining a position of an intracardiac blood pump in a patient are described. The method includes receiving from at least one capacitive sensor associated with a cannula of the intracardiac blood pump, at least one capacitive signal, determining a position of the intracardiac blood pump in the patient based, at least in part, on the at least one capacitive signal, and providing an indication of the position of the intracardiac blood pump on a user interface of the circulatory support device.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/867 - Devices for guiding or inserting pumps or pumping devices into the patient’s body using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
A dual-band phosphor-converted light emitting diode (PC-LED) is provided. The dual-band PC-LED includes a blue LED configured to generate blue light, a first phosphor-based light filter configured to output visible light based on the blue light; and a second phosphor-based light filter configured to output near-infrared light based on the visible light.
An optical assembly for placement on a medical device. The optical assembly has a diaphragm suspended on and over an optical cavity. The optical cavity has a sensor dot formed thereon. The diaphragm is covered with a biocompatible platinum silicide layer.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/816 - Sensors arranged on or in the housing, e.g. ultrasound flow sensors
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
G01L 7/08 - Measuring the steady or quasi-steady pressure of a fluid or a fluent solid material by mechanical or fluid pressure-sensitive elements in the form of elastically-deformable gauges of the flexible-diaphragm type
A61M 60/221 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having both radial and axial components, e.g. mixed flow pumps
A catheter may be provided. The catheter may include an expandable occlusion element coupled to an external surface of a tubular body at a proximal end of the expandable occlusion element and a distal end of the expandable occlusion element. An inner surface of the expandable occlusion element may define a volume of space between the inner surface of the expandable occlusion element and an external surface of the tubular body. The catheter may include a plurality of lumens. A first lumen may be configured to allow a first fluid to be introduced and/or removed from the volume of space defined by the inner surface of the expandable occlusion element. A second lumen may be configured to receive a pressure sensor or define a fluid-filled pressure transducer. A third lumen may be configured to allow a second fluid to be removed from the volume of space.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Disclosed are devices and systems utilizing specifically designed catheters. The catheters may include a tubular body having a first end and a second end. The tubular body may have an outer diameter that is no more than 9 Fr. The tubular body may define a plurality of lumen extending at least partially through the catheter (e.g., from the first end towards the second end). A first lumen may be configured to slidably receive a guidewire. A second lumen may be configured to inflate and/or deflate a first expandable occlusion element. A third lumen may be configured to inflate and/or deflate a second expandable occlusion element. The catheter may include a plurality of additional lumen.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Various devices, systems, and techniques are provided for purging blood pumps. A purge apparatus may be provided that may include a housing having a hinged lid defining a first surface of the housing. The hinged lid may be configured to allow access to an internal volume of space of the housing. The housing may have an opening on a second surface opposite the first surface. The housing may define a tubing channel configured to receive at least a portion of a tube. The purge apparatus may include a pumping mechanism configured to be operably connected to a motor through the opening. The pumping mechanism may be disposed within the internal volume of space of the housing. The pumping mechanism may be configured to, during operation, compress the tube extending through the purge apparatus so as to continuously maintain a positive pressure downstream of the pumping mechanism.
A console associated with a medical device is provided. The console includes a user interface, a visual indicator separate from the user interface, and a controller. The controller is configured to control an operation of the medical device, receive data from the medical device, display an indication of the data on the user interface, and change an output of the visual indicator based, at least in part, on the data.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/508 - Electronic control means, e.g. for feedback regulation
A61M 60/829 - Sealings between moving parts having a purge fluid supply
An expandable introducer sheath with a dilator configured to trap the distal tip of the introducer sheath. In some examples, the dilator may have a tip configured to slide relative to the body of the dilator, such that moving the dilator body in the proximal direction relative to the dilator tip reveals an area in which the outer diameter of the dilator transitions to an area of reduced diameter, and moving the dilator body in the distal direction relative to the dilator tip may enable the distal tip of the introducer sheath to become trapped.
A percutaneously insertable blood pump assembly comprises a pump section, a catheter attached to a proximal end of the pump section, a first apertured section distal to the pump section and in fluid communication therewith, a cannula affixed to and in fluid communication with the first apertured section, and a second apertured section distal to the cannula and in fluid communication therewith. One of the first and second apertured section is a blood outlet from the cannula. The blood outlet has a body portion, an apertured portion, and a ring portion. The plurality of struts in the apertured portion extend from and join the body portion to the ring portion. The struts are asymmetric along at least a portion of their length from the body portion of the outlet to the ring portion of the outlet.
A61M 60/90 - Details not provided for in groups , or
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A distal extension for a blood pump may be provided. The distal extension may include a tubular body. The distal end of the tubular body may be coupled to an intermediate point on the tubular body to form a closed loop at a distal end of an atraumatic distal extension. The closed loop may define an aperture extending through the closed loop, the closed loop having a central plane parallel to a central axis of the tubular body at the proximal end. In various aspects, the tubular body may include a bend. The bend may define an angle between a central axis of a first substantially straight section of the tubular body proximal to the bend and a central axis of a second substantially straight section of the tubular body distal to the bend. In various aspects, the closed loop may be a non-circular closed loop.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/408 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
An expandable introducer sheath assembly (100) having an expandable sheath body (130) with a dilator assembly (200) having a dilator body (210) configured to trap the distal tip of the introducer sheath (150). The dilator body has a tip (220) configured to slide relative to the body of the dilator, such that moving the dilator body in the proximal direction relative to the dilator tip reveals an area in which the outer diameter of the dilator transitions to an area of reduced diameter, and moving the dilator body in the distal direction relative to the dilator tip may enable the distal tip of the introducer sheath to become trapped.
An expandable introducer sheath with a dilator configured to trap the distal tip of the introducer sheath. In some examples, the dilator may have a tip configured to slide relative to the body of the dilator, such that moving the dilator body in the proximal direction relative to the dilator tip reveals an area in which the outer diameter of the dilator transitions to an area of reduced diameter, and moving the dilator body in the distal direction relative to the dilator tip may enable the distal tip of the introducer sheath to become trapped. Likewise, in some examples, the dilator may be equipped with a collet configured to open and close as the dilator tip slides relative to the body of the dilator.
Methods and apparatus for determining a position of an intracardiac blood pump in a patient are described. The method includes receiving from at least one capacitive sensor associated with a cannula of the intracardiac blood pump, at least one capacitive signal, determining a position of the intracardiac blood pump in the patient based, at least in part, on the at least one capacitive signal, and providing an indication of the position of the intracardiac blood pump on a user interface of the circulatory support device.
Methods and apparatus for providing sensory feedback to an operator of a mechanical circulatory support (MCS) device are provided. The method comprises monitoring, using a controller of the MCS device, one or more physiological signals associated with a heart of a patient within which the MCS device is placed, generating an alert signal based, at least in part, on the monitored one or more physiological signals, and transmitting in response to generating the alert signal, a control signal from the controller of the MCS to a feedback device, wherein the feedback device is configured to provide sensory feedback to an operator of the MCS device based on the control signal.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A distal extension for a blood pump may be provided. The distal extension may include a tubular body. The distal end of the tubular body may be coupled to an intermediate point on the tubular body to form a closed loop at a distal end of an atraumatic distal extension. The closed loop may define an aperture extending through the closed loop, the closed loop having a central plane parallel to a central axis of the tubular body at the proximal end. In various aspects, the tubular body may include a bend. The bend may define an angle between a central axis of a first substantially straight section of the tubular body proximal to the bend and a central axis of a second substantially straight section of the tubular body distal to the bend. In various aspects, the closed loop may be a non-circular closed loop.
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/865 - Devices for guiding or inserting pumps or pumping devices into the patient’s body
An expandable introducer sheath (130) with a dilator (610) configured to trap the distal tip (150) of the introducer sheath. In some examples, the dilator may have a tip (620) configured to slide relative to the body of the dilator, such that moving the dilator body in the proximal direction relative to the dilator tip reveals an area in which the outer diameter of the dilator transitions to an area of reduced diameter, and moving the dilator body in the distal direction relative to the dilator tip may enable the distal tip of the introducer sheath to become trapped. Likewise, in some examples, the dilator may be equipped with a collet configured to open and close as the dilator tip slides relative to the body of the dilator.
A percutaneously insertable blood pump assembly comprises a pump section, a catheter attached to a proximal end of the pump section, a first apertured section distal to the pump section and in fluid communication therewith, a cannula affixed to and in fluid communication with the first apertured section, and a second apertured section distal to the cannula and in fluid communication therewith. One of the first and second apertured section is a blood outlet from the cannula. The blood outlet has a body portion, an apertured portion, and a ring portion. The plurality of struts in the apertured portion extend from and join the body portion to the ring portion. The struts are asymmetric along at least a portion of their length from the body portion of the outlet to the ring portion of the outlet.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/221 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having both radial and axial components, e.g. mixed flow pumps
An expandable sheath for use in an intravascular blood pump. The sheath has a sheath frame surrounded by one or more sleeves. The frame may have at least one of a braid, a wound wire, and a laser-cut material. The sheath frame may be a metal that is at least one of Nitinol and stainless steel. The sleeves may be made of one or more plastics. The expandable sheath is manufactured by surrounding the sheath frame with the sleeves and heating the sleeves and the frame around a mandrel. The frame and sleeves are heated in multiple steps, along multiple areas of the sheath, and to different temperatures and for different time periods. The temperatures at which the sheath is heated, and the time periods over which the sheath is heated, are selected such that after heating, the materials of the plastic sleeves penetrate the sheath frame to various depths.
G08B 21/04 - Alarms for ensuring the safety of persons responsive to non-activity, e.g. of elderly persons
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
37.
METHOD AND APPARATUS FOR DELIVERING AN OXYGENATED FLUID
A blood pump that delivers an oxygenated-fluid assists with a patient's cardiovascular function by increasing the oxygenation of the blood. Disclosed is a system and method for delivering an oxygenated fluid. The system includes a blood pump, a catheter operably coupled to the blood pump, and a purge fluid line including a first lumen configured to deliver a purge fluid to a motor section of the blood pump, at least a portion of the purge fluid line extending along a catheter, wherein the purge fluid is an oxygenated purge fluid.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/829 - Sealings between moving parts having a purge fluid supply
38.
METHOD AND APPARATUS FOR DELIVERING AN OXYGENATED FLUID
A blood pump that delivers an oxygenated-fluid assists with a patient's cardiovascular function by increasing the oxygenation of the blood. Disclosed is a system and method for delivering an oxygenated fluid. The system includes a blood pump, a catheter operably coupled to the blood pump, and a purge fluid line including a first lumen configured to deliver a purge fluid to a motor section of the blood pump, at least a portion of the purge fluid line extending along a catheter, wherein the purge fluid is an oxygenated purge fluid.
A61M 60/829 - Sealings between moving parts having a purge fluid supply
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
39.
SYSTEMS AND METHOD FOR IMPROVED SURGICAL OR GRAFT ACCESS
A graft system may be provided. The graft system may include a graft, a hemostasis valve operably coupled to a proximal end of the graft, and a clamp disposed around the proximal end of the graft and configured to hold the hemostasis valve in place relative to the graft. The graft may include a woven or knitted fabric. The clamp may be removably, or permanently, attached to the graft. The hemostasis valve may include a slit membrane disposed within a housing. The hemostasis valve may include an introducer sheath coupled to the housing. The housing may include two portions coupled together along two axial seams, each axial seam extending from a proximal end to a distal end of the hemostasis valve. A grommet may be coupled to an end of the graft.
A graft system may be provided. The graft system may include a graft, a hemostasis valve operably coupled to a proximal end of the graft, and a clamp disposed around the proximal end of the graft and configured to hold the hemostasis valve in place relative to the graft. The graft may include a woven or knitted fabric. The clamp may be removably, or permanently, attached to the graft. The hemostasis valve may include a slit membrane disposed within a housing. The hemostasis valve may include an introducer sheath coupled to the housing. The housing may include two portions coupled together along two axial seams, each axial seam extending from a proximal end to a distal end of the hemostasis valve. A grommet may be coupled to an end of the graft.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/865 - Devices for guiding or inserting pumps or pumping devices into the patient’s body
A blood pump with a stator and rotor wherein the rotor is assembled by bonding the stator components with epoxy. The bonding surfaces of the rotor components are primed with a silane-based primer to improve adhesion between the primer and the rotor components by rendering such surfaces hydrophobic. A bonding surface of one of the stator yoke or the stator sleeve, or both, is treated with a primer that improves wettability of the bonding surface and improves bonding of the epoxy to the binding surface. The device has a bonding surface adhered to epoxy in which a primer was applied on such bonding surface prior to introducing epoxy onto the bonding surface. In addition to improved bond strength, hydrophobic surface would control moister ingress.
A61M 60/411 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
A blood flow rate measurement system measures fluid flow rate in a blood vessel having a catheter-based heart pump inserted therein, without relying on measurements of electric current drawn by a motor that drives the heart pump. A turbine is disposed at or near a distal end of the heart pump catheter. Blood or other fluid flowing through the blood vessel urges blades of the turbine to rotate. The turbine is mechanically coupled to a signal generator, which generates a signal indicative of a rotational speed of the turbine, which is dependent, at least in part, on speed of the fluid flowing through the blood vessel. A tachometer, external to the body of the patient, calculates the blood flow rate from the rotational speed of the turbine. In some cases, the blades are collapsible, to reduce diameter of the turbine, thereby facilitating insertion of the system into the blood vessel.
A61B 5/027 - Measuring blood flow using electromagnetic means, e.g. electromagnetic flow meter using catheters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
G01F 1/075 - Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by using mechanical effects using rotating vanes with tangential admission with magnetic or electromagnetic coupling to the indicating device
Methods and systems are provided for the circulation of blood using a purge-free miniature pump. In one embodiment, a pump is provided that may comprise a housing including a rotor and a stator within a drive unit. In this embodiment, the pump may establish a primary blood flow through the space between the drive unit and the housing and a secondary blood flow between the rotor and stator. In another embodiment, a pump establishes a primary blood flow outside the housing and a secondary blood flow between the rotor and stator. In yet another embodiment, a method is provided for introducing the pump into the body and circulating blood using the pump.
F04D 13/06 - Units comprising pumps and their driving means the pump being electrically driven
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/165 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
Methods and apparatus for predicting decoupling during a non-cardiac medical procedure are provided. The method includes receiving one or more patient characteristics associated with a patient scheduled for a non-cardiac medical procedure, providing the one or more patient characteristics as input to a machine learning model trained to output a decoupling prediction, processing, using at least one computer processor, the one or more patient characteristics using the machine learning model to output a decoupling prediction for the patient, wherein the decoupling prediction is associated with the non-cardiac medical procedure, and displaying, on a user interface, an indication of the decoupling prediction for the patient output from the machine learning model.
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
45.
METHODS AND APPARATUS FOR PREDICTING DECOUPLING DURING NON-CARDIAC MEDICAL PROCEDURES
Methods and apparatus for predicting decoupling during a non-cardiac medical procedure are provided. The method includes receiving one or more patient characteristics associated with a patient scheduled for a non-cardiac medical procedure, providing the one or more patient characteristics as input to a machine learning model trained to output a decoupling prediction, processing, using at least one computer processor, the one or more patient characteristics using the machine learning model to output a decoupling prediction for the patient, wherein the decoupling prediction is associated with the non-cardiac medical procedure, and displaying, on a user interface, an indication of the decoupling prediction for the patient output from the machine learning model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
46.
OVERMOLD TECHNIQUE FOR PEEL-AWAY INTRODUCER DESIGN
A method for manufacturing a medical introducer includes placing an introducer sheath onto a mandrel, and overmolding an introducer hub onto a proximal end of the introducer sheath. The introducer sheath has one or more score lines formed on an inner surface and the mandrel has a number of surface protrusions so that when the introducer sheath is positioned on the mandrel, each of the surface protrusions contacts one of the score lines formed on the introducer sheath. The surface protrusions on the mandrel prevent plastic material from the introducer hub from contacting the score lines thereby maintaining the score lines during the overmolding.
A61M 25/06 - Body-piercing guide needles or the like
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
A method for automatically classifying clinical descriptions of patients by a computer processor using natural language processing is provided. The clinical descriptions relate to the use of a ventricular assist device to treat the patient. The method comprises receiving at least one clinical description comprising text. The method also then comprises determining the position of a target word within the text. Further the method comprises determining the existence of at least one negation word within an active region, the active region comprising a predetermined number of words within the text occurring immediately before and immediately after the target word, including the target word. The method then comprises determining the existence of at least one body-part word within the active region. Lastly, the method comprises determining that the clinical description is to be disregarded if the active region contains either a negation word or a body-part word.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
Disclosed is an access device for vascular grafts. The access device may allow two large-bore medical devices to be inserted simultaneously. The access device may include a body defining a common arm, a first proximal arm, and a second proximal arm. The common arm may include a common lumen extending from a distal end of the common arm to a proximal end of the common arm. The first arm may include a first lumen extending from a proximal end of the first arm to the common lumen. The second arm may include a second lumen extending from a proximal end of the second arm to the common lumen. The access device may include a plurality of hemostasis valves. A first hemostasis valve may be disposed at the proximal end of the first proximal arm. A second hemostasis valve may be disposed at the proximal end of the second proximal arm.
Disclosed is a guidewire for use in, e.g., procedures requiring axillary access and enhanced echo echogenicity. The guidewire may include a proximal portion and a distal portion. The distal portion may include a tapered core wire extending from the proximal portion to a distal tip. The distal portion may have surface texturing on at least one surface near a distal end of the distal portion. The guidewire may have, e.g., a 180° J-tip operably coupled to the tapered core wire. At least a portion of the J-tip may have a stiffness less than a stiffness of the tapered core wire. The J-tip may include a metal-filled polymer, such as a tungsten-filled polyurethane. The tapered core wire may have a maximum diameter of 0.6-0.7 mm, and may have a tapered length of 70-120 mm.
Disclosed is an access device for vascular grafts. The access device may allow two large-bore medical devices to be inserted simultaneously. The access device may include a body defining a common arm, a first proximal arm, and a second proximal arm. The common arm may include a common lumen extending from a distal end of the common arm to a proximal end of the common arm. The first arm may include a first lumen extending from a proximal end of the first arm to the common lumen. The second arm may include a second lumen extending from a proximal end of the second arm to the common lumen. The access device may include a plurality of hemostasis valves. A first hemostasis valve may be disposed at the proximal end of the first proximal arm. A second hemostasis valve may be disposed at the proximal end of the second proximal arm.
Devices and methods for providing a kink resistant peel away sheath are disclosed. One device includes a sheath for insertion into a vasculature of a patient. The sheath comprises a sheath body having an outer surface, a longitudinal axis and a lumen formed therethrough. The sheath body comprises an inner layer arranged about the longitudinal axis, an outer layer coaxially arranged with the inner layer, and a support layer positioned between the inner and outer layers, wherein the inner, outer and support layers are laminated together to form the sheath body. The sheath also comprises at least one shear line positioned beneath the outer surface of the sheath body, and configured to facilitate the longitudinal separation of the sheath body along the at least one shear line.
Disclosed is a guidewire for use in, e.g, procedures requiring axillary access and enhanced echo echogenicity. The guidewire may include a proximal portion and a distal portion. The distal portion may include a tapered core wire extending from the proximal portion to a distal tip. The distal portion may have surface texturing on at least one surface near a distal end of the distal portion. The guidewire may have, e.g., a 180° J-tip operably coupled to the tapered core wire. At least a portion of the J-tip may have a stiffness less than a stiffness of the tapered core wire. The J-tip may include a metal-filled polymer, such as a tungsten-filled polyurethane. The tapered core wire may have a maximum diameter of 0.6-0.7 mm, and may have a tapered length of 70-120 mm.
Systems and methods for providing a reinforced cannula for use in a blood pump assembly. The reinforced cannula comprises one or more thermoformed reinforced end portions. The thermoformed reinforced end portions may be stiffer than a medial portion of the cannula, allowing the medial portion of the cannula body to stretch and bend more readily than the cannula ends when the cannula is subject to an applied stress, reducing the stress and strain on the cannula ends.
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
Methods and systems for using mechanical circulatory support concurrently with a biologic therapy (e.g. a gene therapy vector). Particular adaptations include a cardiac therapy method in which a blood vessel such as a coronary artery or blood vessel is occluded, followed by injecting a gene therapy vector or biologic distal to the occlusion site and waiting a certain amount of time, while using the mechanical circulatory support system to provide circulatory support to the patient.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
Systems and techniques for improving cardiorenal syndrome (CRS) may be provided. The systems may include a first flow enhancer configured to increase a renal artery' pressure. The systems may include a second flow enhancer or flow restrictor configured to reduce a renal vein pressure. Each flow enhancer or flow restrictor may be configured to increase atransrenal pressure gradient, improve filtering and renal perfusion.
A61M 60/226 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
A61M 60/411 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
57.
CARDIORENAL SYNDROME (CRS) THERAPY SYSTEMS AND METHODS
e.ge.g, a blood pump, a blood flow or pressure restrictor or enhancer. The system may include a controller operably coupled to the therapy-delivery device. The controller may be configured to adjust a therapy delivered by the therapy-delivery device based on a parameter related to renal function. The parameter may be measured by a real-time diagnostic sensor. The real-time diagnostic sensor may be integral to the therapy-delivery device, or may be located remotely from the therapy-delivery device, such as on a separate implantable device, or on a wearable medical device.
A61M 60/33 - Medical purposes thereof other than the enhancement of the cardiac output for enhancement of in vivo organ perfusion, e.g. retroperfusion of kidneys
A61M 60/515 - Regulation using real-time patient data
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 5/0205 - Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
A61B 5/029 - Measuring blood output from the heart, e.g. minute volume
A61B 5/352 - Detecting R peaks, e.g. for synchronising diagnostic apparatusEstimating R-R interval
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/554 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
Various devices, systems, and methods are disclosed. The method may include determining a body surface area of a patient (who may have a body surface area of about 0.6 m2 to about 1.3 m2), selecting a blood pump from a plurality of differently sized blood pumps based on the body surface area of the patient, implanting the blood pump, and activating the blood pump to provide support to the patient. The selected blood pump may have a cannula connecting an inlet and an outlet. The cannula may have a bend and a cannula length measuring an axial length between the inlet and the outlet. The cannula length may be between about 30 mm to about 46 mm if the body surface area is less than 0.9 m2.
A61M 60/117 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/515 - Regulation using real-time patient data
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/829 - Sealings between moving parts having a purge fluid supply
Various devices, systems, and methods are disclosed. The method may include determining a body surface area of a patient (who may have a body surface area of about 0.6 m2 to about 1.3 m2), selecting a blood pump from a plurality of differently sized blood pumps based on the body surface area of the patient, implanting the blood pump, and activating the blood pump to provide support to the patient. The selected blood pump may have a cannula connecting an inlet and an outlet. The cannula may have a bend and a cannula length measuring an axial length between the inlet and the outlet. The cannula length may be between about 30 mm to about 46 mm if the body surface area is less than 0.9 m2.
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A61M 60/855 - Constructional details other than related to driving of implantable pumps or pumping devices
A61M 60/80 - Constructional details other than related to driving
A61M 60/802 - Constructional details other than related to driving of non-positive displacement blood pumps
A61M 60/122 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body
A61M 60/126 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel
A61M 60/165 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
61.
Display panel or portion thereof with graphical user interface
There is provided an intravascular blood pump for insertion into a patient's heart. The blood pump comprises a slotless permanent magnet motor contained within a housing, the motor having p magnet pole pairs and n phases, where p is an integer greater than zero, and n is an integer ≥3. The motor comprises a stator extending along a longitudinal axis of the housing and having 2np coils wound to form two coils per phase per magnet pole pair. The stator comprises inner and outer windings each comprising np coils electrically connected such that the current flowing through the coils is in the same direction, the coils of the outer winding arranged on an outer surface of the coils of the inner winding.
A61M 60/419 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/237 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/508 - Electronic control means, e.g. for feedback regulation
H02K 3/28 - Layout of windings or of connections between windings
H02K 15/03 - Processes or apparatus specially adapted for manufacturing, assembling, maintaining or repairing of dynamo-electric machines of stator or rotor bodies having permanent magnets
63.
METHODS AND APPARATUS FOR ESTIMATING WEANING STATUS FOR A MECHANICAL CIRCULATORY SUPPORT DEVICE
Methods and apparatus for determining a weaning status for a patient associated with a mechanical circulatory support device are provided. The method includes receiving a set of signals from the mechanical circulatory support device implanted in a heart of a patient, determining, using a computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a weaning status for the patient, and displaying, on a user interface associated with the mechanical circulatory support device, an indication of the weaning status for the patient output from the machine learning model.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
A guidewire device, including a system, kit, and method of use, are disclosed. The guidewire device may include a proximal guidewire portion operably coupled to a proximal joint, which is operably coupled to an expandable portion, which is operably coupled to a distal joint, which is operably coupled to a distal tip portion. The proximal guidewire portion may include a first flexible sidewall defining a first central lumen and may include a tubular member defining a pressure lumen. The proximal joint may include a proximal hypotube. The expandable portion may include an expandable sidewall defining a second central lumen and may be fluidly coupled to the pressure lumen. The expandable portion may have a deflated configuration and an inflated configuration. The distal joint may include a distal hypotube. The distal tip portion may include a second flexible sidewall defining a third central lumen.
A system and method for vasculature closure from a single access point are provided, utilizing specifically designed bioresorbable devices. The bioresorbable devices may include a disk-shaped substrate layer with an opening extending from a first surface to a second surface, configured to allow a guidewire to pass through, and a coating configured to encourage adhesion to an interior vessel wall. The system utilizes a guidewire having an expandable portion passing through the opening. The bioresorbable device is carried into the blood vessel within a first tubular member in a compressed configuration, and then ejected from the first tubular member by a second tubular member. The bioresorbable member then assumes a partially expand configuration. The expandable portion of the guidewire can then be used to press the bioresorbable device against an interior vessel wall, allowing it to adhere, after which the expandable portion can be deflated.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A guidewire device, including a system, kit, and method of use, are disclosed. The guidewire device may include a proximal guidewire portion operably coupled to a proximal joint, which is operably coupled to an expandable portion, which is operably coupled to a distal joint, which is operably coupled to a distal tip portion. The proximal guidewire portion may include a first flexible sidewall defining a first central lumen and may include a tubular member defining a pressure lumen. The proximal joint may include a proximal hypotube. The expandable portion may include an expandable sidewall defining a second central lumen and may be fluidly coupled to the pressure lumen. The expandable portion may have a deflated configuration and an inflated configuration. The distal joint may include a distal hypotube. The distal tip portion may include a second flexible sidewall defining a third central lumen.
A system and method for vasculature closure from a single access point are provided, utilizing specifically designed bioresorbable devices. The bioresorbable devices may include a disk-shaped substrate layer with an opening extending from a first surface to a second surface, configured to allow a guidewire to pass through, and a coating configured to encourage adhesion to an interior vessel wall. The system utilizes a guidewire having an expandable portion passing through the opening. The bioresorbable device is carried into the blood vessel within a first tubular member in a compressed configuration, and then ejected from the first tubular member by a second tubular member. The bioresorbable member then assumes a partially expand configuration. The expandable portion of the guidewire can then be used to press the bioresorbable device against an interior vessel wall, allowing it to adhere, after which the expandable portion can be deflated.
A method for providing a treatment recommendation to a physician for treating a patient is disclosed. The method comprises determining, from a processor in communication with a patient data repository, a first treatment recommendation based on a combination of selected patient demographics from the patient data repository applicable to the patient, and operational parameters of a plurality of ventricular assist devices (VADs) suitable for treating the patient, the first treatment recommendation having a first survival rate and comprising the use of a first VAD. The method then obtains a first signal from using the first VAD on the patient. The method then determines a second treatment recommendation based on the first signal and the first treatment recommendation, the second treatment recommendation having a second survival rate. The method then provides the second treatment recommendation to the physician if the second survival rate is higher than the first survival rate.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A heart pump assembly, also referred to as catheter assembly, having a desired anatomical shape is provided. The catheter assembly can include a catheter and a cannula having a bend between a proximal portion and a distal portion. A resting shape of the catheter and the cannula can be selected to allow the distal cannula portion to be positioned at a desired angle relative to an anatomical plane (e.g., a plane of an aortic arch). In some embodiments, a packaging tray can be designed to set the catheter assembly in a desired resting shape. For example, the proximal cannula portion can be positioned at a first angle relative to the catheter, and the proximal cannula portion can be positioned at a second angle out of the plane of the packaging tray via one or more inserts.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A blood pump system includes a catheter, a pump housing disposed distal of a distal end of the catheter, a rotor positioned at least partially in the pump housing, a controller, and an electrode coupled a distal region of the blood pump. The electrode can be used to sense electrocardiogram (EKG) signals and transmit the signals to a controller of the blood pump. The operation of the blood pump can be adjusted based on the EKG signal and on cardiac parameters derived from the EKG signal. Further, the controller can determine a need for defibrillation or pacing of the patient's heart based on the signal and can administer treatment with electrical shocks to the heart via the electrode coupled to the blood pump. The use of an electrode with a blood pump already in place in the heart allows for more efficient and safer treatment of serious cardiac conditions.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A method and system for improving kidney function of a patient may be provided. The method may include activating a baroreceptor, and improving a flow of blood through vasculature of the patient. This may include positioning a stent at or near a baroreceptor, the stent configured to stretch the vasculature. This may include positioning a lead at or near a baroreceptor, the lead comprising a proximal end and a distal end and an electrode connected to the distal end of the lead, wherein the electrode configured to emit one or more electrical signals, such as an intermittent electrical stimulus or a constant electrical stimulus. The stent may include a tubular body, which may be made of a flexible material.
A method for providing a therapeutic treatment to reduce preload may be provided. The method may include placing a ventricular assist device (VAD) at least partially within either the left or right ventricle of a patient, and placing a catheter-based device comprising an adjustable flow restricting element (FRE) such that the FRE is disposed within a superior vena cava (SVC) of the patient. The method may include receiving information from the VAD and/or the catheter-based FRE device, determining a first determined value based on the information, and controlling at least one performance parameter of the VAD and/or the catheter-based device based on the first determined value.
A61M 60/178 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
75.
METHOD AND APPARATUS FOR IMPROVING KIDNEY FUNCTION
A method and system for improving kidney function of a patient may be provided. The method may include activating a baroreceptor, and improving a flow of blood through vasculature of the patient. This may include positioning a stent at or near a baroreceptor, the stent configured to stretch the vasculature. This may include positioning a lead at or near a baroreceptor, the lead comprising a proximal end and a distal end and an electrode connected to the distal end of the lead, wherein the electrode configured to emit one or more electrical signals, such as an intermittent electrical stimulus or a constant electrical stimulus. The stent may include a tubular body, which may be made of a flexible material.
A method for providing a therapeutic treatment to reduce preload may be provided. The method may include placing a ventricular assist device (VAD) at least partially within either the left or right ventricle of a patient, and placing a catheter-based device comprising an adjustable flow restricting element (PRE) such that the PRE is disposed within a superior vena cava (SVC) of the patient. The method may include receiving information from the VAD and/or the catheter-based PRE device, determining a first determined value based on the information, and controlling at least one performance parameter of the VAD and/or the catheter-based device based on the first determined value.
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
77.
METHODS AND SYSTEMS FOR DETERMINING POSITIONING OF A HEART PUMP
Methods and apparatus for determining a position of a heart pump in a heart of a patient are described. The method includes receiving a pressure signal from at least one pressure sensor arranged on the heart pump, generating a histogram of values observed within a time window associated with the pressure signal, and determining the position of the heart pump based, at least in part, on a morphology of the histogram.
An intravascular blood pump may be provided, that may include a catheter a miniaturized solid state pump section coupled to a distal end of the catheter. The pump section may include an electric motor comprising a stator and a rotor operably coupled to the stator, a rigid drive shaft disposed within the pump section where the drive shaft is operably coupled to the rotor, and an impeller housing in which an expandable impeller is housed, the expandable impeller being coupled to the drive shaft.
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/808 - Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
79.
SYSTEMS AND METHODS FOR DETERMINING CARDIAC CONTRACTILITY BASED ON SIGNALS FROM A MECHANICAL CIRCULATORY SUPPORT DEVICE
Methods and apparatus for estimating a measure of cardiac contractility based on a set of features determined from a set of signals associated with a mechanical circulatory support device are provided. The method includes determining, using computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a measure of cardiac contractility, and performing an action based, at least in part, on the measure of cardiac contractility output by the machine learning model.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/546 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood flow, e.g. by adapting rotor speed
A61M 60/554 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
An intravascular blood pump may be provided, that may include a catheter a miniaturized solid state pump section coupled to a distal end of the catheter. The pump section may include an electric motor comprising a stator and a rotor operably coupled to the stator, a rigid drive shaft disposed within the pump section where the drive shaft is operably coupled to the rotor, and an impeller housing in which an expandable impeller is housed, the expandable impeller being coupled to the drive shaft.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/419 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
A61M 60/538 - Regulation using real-time blood pump operational parameter data, e.g. motor current
Methods and apparatus for determining a weaning status for a patient associated with a mechanical circulatory support device are provided. The method includes receiving a set of signals from the mechanical circulatory support device implanted in a heart of a patient, determining, using a computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a weaning status for the patient, and displaying, on a user interface associated with the mechanical circulatory support device, an indication of the weaning status for the patient output from the machine learning model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
82.
SYSTEMS AND METHODS FOR DETERMINING CARDIAC CONTRACTILITY BASED ON SIGNALS FROM A MECHANICAL CIRCULATORY SUPPORT DEVICE
Methods and apparatus for estimating a measure of cardiac contractility based on a set of features determined from a set of signals associated with a mechanical circulatory support device are provided. The method includes determining, using computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a measure of cardiac contractility, and performing an action based, at least in part, on the measure of cardiac contractility output by the machine learning model.
An unloading system may be provided for use with ECMO and mechanical circulatory support (MCS) devices. The system may include a first cannula with a distal cannula body coupled to a proximal hub, the distal body having an inner diameter, where the first cannula is configured to slidably receive the MCS device. The system may include a second cannula having an outer diameter smaller than the outer diameter of the first cannula. The system may include a connector for splitting a flow of blood from the ECMO device to the first and second cannula. The system may be configured so a first total pressure drop of the first cannula with the MCS device in place in the first cannula with the second cannula connected to the connector is equal to a second total pressure drop of the first cannula without the MCS device in place in the first cannula.
A61M 39/06 - Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
84.
METHODS AND SYSTEMS FOR DETERMINING POSITIONING OF A HEART PUMP
Methods and apparatus for determining a position of a heart pump in a heart of a patient are described. The method includes receiving a pressure signal from at least one pressure sensor arranged on the heart pump, generating a histogram of values observed within a time window associated with the pressure signal, and determining the position of the heart pump based, at least in part, on a morphology of the histogram.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/531 - Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
A61M 60/867 - Devices for guiding or inserting pumps or pumping devices into the patient’s body using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
85.
Display panel or portion thereof with graphical user interface
There is provided an intravascular blood pump for insertion into a patient's body. The system comprises a slotless motor having p magnet pole pairs and n phases, where p is an integer greater than zero, and n is an integer≥3. The motor comprises a stator winding having 2np coils wound to form two coils per phase per magnet pole pair such that a coil from each phase is circumferentially arranged next to a coil from a different phase in a sequential order of phase, the arrangement repeated along the stator winding such that each coil spans 360°/(2np) about the cross section of the stator winding. The motor also comprises a permanent magnet rotor supported for rotation and configured to generate a magnetic flux for interaction with the stator winding. The two coils per phase per magnet pole pair are connected in series.
A61M 60/419 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/139 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
A61M 60/165 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A mechanical circulatory support system for a heart having a cooling element and a method for using the system to treat the effects of a cardiac episode. The support system has a pump comprising a rotor, the rotor having at least one blade. The system also has a catheter having an inner surface and an outer surface, the catheter extending proximally of relative to the pump housing. The outer surface of the catheter is configured to contact blood when disposed within patient vasculature. The outer surface of the catheter comprises a heat transfer surface configured for cooling blood that comes in contact with the outer surface. The support system is operated to provide a temperature selected to cool the circulating blood in contact with the outer surface of the catheter to a temperature selected to reduce or prevent an effect of a cardiac episode.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61F 7/12 - Devices for heating or cooling internal body cavities
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/135 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/17 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/36 - Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatmentMedical purposes thereof other than the enhancement of the cardiac output for specific therapy
A61M 60/422 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
An expandable introducer sheath with an interlock dilator. The present technology provides an expandable sheath with a step feature inside its distal opening, and a dilator with an interlock that includes a catch surface configured to engage with the step feature and resist further relative movement so that the body of the dilator is prevented from exiting the distal end of the expandable sheath. This interlocking engagement may allow the dilator to be used to extend and maintain tension on the expandable sheath during insertion into a patient, and then to be retracted from the expandable sheath by pulling the dilator in the opposite direction. The present technology also provides a dilator hub with a spring mechanism configured to achieve and maintain a desired tension on the expandable sheath and to prevent overextension of the expandable sheath when the dilator is being inserted into the expandable sheath.
Systems and methods are provided for insertion of a medical device into a blood vessel. The system may include a sheath assembly with an introducer sheath and a variable size repositioning sheath. The variable size repositioning sheath may be configured to be adjustable in size in a radial direction and to be inserted into the blood vessel or an expandable introducer sheath. In some aspects, the system may include an intracardiac device such as a blood pump with an elongate catheter.
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/174 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
A61M 60/414 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
A61M 60/416 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
A61M 60/554 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
A61M 60/816 - Sensors arranged on or in the housing, e.g. ultrasound flow sensors
A61M 60/829 - Sealings between moving parts having a purge fluid supply
A61M 60/865 - Devices for guiding or inserting pumps or pumping devices into the patient’s body
An expandable medical sheath can include a sheath body having a lumen that extends between proximal and distal ends of the sheath. The sheath can have first and second members where the first member has a different elastic modulus than the second member such that one provides elasticity to the sheath and the other provides column strength. The first and second members can be coupled together in alternating sections to form the tubular sheath or the stiffer members can be embedded in the elastic member along all or a portion of the longitudinal length of the sheath. The sheath can automatically move to an expanded state to allow a larger diameter medical device to pass through the lumen, and once through the sheath can automatically return to its initial diameter.
Techniques for delaying initiation of coagulation and suppressing fibrin formation may be provided. The disclosed techniques may include providing a percutaneous blood pump that may include a metal or ceramic surface (such as a surface of a shaft, bearing, rotor, stator, etc.) that has been modified with a bifunctional modifier. The modified surface may be within a motor section and/or pump section of the blood pump. The modified surface may be configured to interact with blood. When blood is allowed to interact with the modified surface, a desirable microenvironment may be formed. The bifunctional modifier may be a functionalized aminosilane, a functionalized aminosiloxane, and/or a functionalized silanetriol. The blood pump may be configured to have a purge fluid pass through at least a portion of the motor section and/or the pump section. The purge fluid may be free of anticoagulants.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
A61M 60/226 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
A61M 60/411 - Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
Techniques for delaying initiation of coagulation and suppressing fibrin formation may be provided. The disclosed techniques may include providing a percutaneous blood pump that may include a metal or ceramic surface (such as a surface of a shaft, bearing, rotor, stator, etc.) that has been modified with a bifunctional modifier. The modified surface may be within a motor section and/or pump section of the blood pump. The modified surface may be configured to interact with blood. When blood is allowed to interact with the modified surface, a desirable microenvironment may be formed. The bifunctional modifier may be a functionalized aminosilane, a functionalized aminosiloxane, and/or a functionalized silanetriol. The blood pump may be configured to have a purge fluid pass through at least a portion of the motor section and/or the pump section. The purge fluid may be free of anticoagulants.
A61M 60/13 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
Medical devices, namely, oxygenators for extracorporeal cardiac and respiratory support; extracorporeal membrane oxygenation systems consisting of blood pumps, oxygenators, gas control, catheters, and cannula
