The invention relates to a one-component medical composition in the form of a hydrogel which comprises silicate nanoparticles, water, a hydrogel-forming synthetic polymer and one or more bio-based proteins and/or polymers. Such a composition can be used as a flexible substitute for coil implants in the treatment of aneurysms, tumours or arteriovenous malformations, and due to its extensive biodegradability and improved tolerability, makes long-term anticoagulation therapy unnecessary. The present invention also relates to devices filled with such a composition, and kits which contain such compositions or devices as one component and a medical device, in particular in the form of a stent, as another component.
The invention relates to a medical implant with a self-expandable tubular braided structure (10) made of meshes (11). The braided structure (10) is made of at least one wire (12), in particular an individual wire (12), made of a core material which is visible by x-ray and a casing material, and both ends (13) of the braided structure (10) have closed loops (14a, 14b). The braided structure (10) exerts an expansion force COF during a radial expansion, wherein - the expansion force COF equals between 4 mmHg and 75 mmHg, in particular maximally 25 mmHg, in the case of a lower diameter LIU used for the braided structure (10) of 4 mm to 6 mm, a mesh size of 0.4 mm2 to 0.7 mm2, and a wire diameter of 80 µm to 90 µm, in particular 85 µm; - the expansion force COF equals between 4 mmHg and 60 mmHg, in particular maximally 12 mmHg, in particular maximally 50 mmHg, in the case of an average diameter MIU used for the braided structure (10) of 6 mm to 8 mm, a mesh size of 0.7 mm2to 1.2 mm2, and a wire diameter of 80 µm to 90 µm, in particular 85 µm; and the expansion force COF equals between 3 mmHg and 15 mmHg, in particular maximally 10 mmHg, in the case of an upper diameter UIU used for the braided structure (10) of 8 mm to 10 mm, a mesh size of 1.2 mm2to 1.6 mm2, and a wire diameter of 90 µm to 110 µm, in particular 100 µm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A medical implant for treating a local lesion (100) in a bifurcation of a vessel, in particular for treating a bifurcation aneurysm, having a support body (10) which is compressible and expandable, wherein the support body (10) comprises a proximal portion (11) and a distal portion (12) which are connected to each other, characterized in that - the distal portion (12) for anchoring in the vessel is tubular, in particular cylindrical, and - the proximal portion (11) is conical and has an opening angle (α) with respect to a longitudinal axis (L) of the support body (10), wherein the proximal portion (11) can be positioned in the vessel in such a manner that the vessel and/or the lesion (100) is accessible in the implanted state through the proximal portion (12) with a supply device, in particular a micro-catheter, and - a covering (13) is arranged on the proximal and/or distal portion in such a way that the lesion (100) can be at least partially covered by the covering (13).
The invention relates to a stent with a self-expandable, tubular braided structure (10) of meshes (11), wherein the braided structure (10) is formed by at least one wire (12), in particular a single wire (12), of an x-ray-visible core material and a sheathing material and both ends (13) of the braided structure (10) have closed loops (14a, 14b), wherein - the braided structure (10) has at least one marker element (15), which is arranged between the two ends (13), in particular centrally with respect to the braided structure (10), and - the braided structure (10) has in the rest state a diameter of between 7 and 12 mm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
5.
IMPLANT, MORE PARTICULARLY STENT, AND METHOD OF PRODUCTION
A medical implant, more particularly a stent, having a tubular lattice structure which can be transferred from a radially expanded compressed state to a radially compressed expanded state and has lattice elements that delimit the cells of the lattice structure and have an element surface. In order to enlarge the element surface of each lattice element a polymer nanostructure is distributed over the entire element surface of the lattice element and adheres to it, and an antithrombogenic coating is provided and extends across the lattice element structure surface enlarged by means of the polymer nanostructure.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A medical device for insertion into an organ of the body, with a compressible and expandable mesh structure having struts which are connected together by strut connectors and delimit closed cells of the mesh structure, wherein respectively, two of the struts of at least one cell are disposed opposite each other and form a first strut pair and a second strut pair, wherein one of the two strut pairs is connected together by at least one connecting strut which extends into the cell and bridges it.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention relates to a medical device, in particular a stent, having a self-expandable mesh structure, which is at least partially tubular and is able to widen automatically from a compressed cross-sectional diameter to an expanded cross-sectional diameter, wherein the mesh structure has at least one mesh structure element (10) which is encased, in particular in its entirety, by a nanostructure coating formed of fibrin nanofibres (11, 12), wherein the nanostructure coating has a first layer (L1), which forms an in particular felt-like or fleece-like matrix of crosslinked fibrin fibres (11), wherein some fibrin fibres (12) protrude freely above the first layer (L1), and a second layer (L2) of an in particular nap-like single-fibre structure, and wherein the nanostructure coating additionally contains a growth factor or a peptide having the functional structure of a growth factor, which growth factor or peptide is integrated in the first layer (L1) and/or the second layer (L2).
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
D04C 1/06 - Braid or lace serving particular purposes
A61F 2/848 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
9.
MEDICAL DEVICE, SET HAVING A MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME
The invention relates to a medical device (10) for treating aneurysms, which is transferable from a radially compressed state into a radially expanded state, wherein the device (10) comprises an at least partially tubular lattice structure (11) with multiple cell-forming crosspieces (12) and at least one electrospun membrane (13) which at least partially covers the lattice structure (11) radially on the outside, wherein the membrane (13) has at least one anti-adhesion layer for moving atraumatically in a blood vessel.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
10.
STENT, IN PARTICULAR FOR TREATING CAROTID ARTERY DISEASES
The disclosure relates to a stent, in particular for treating carotid artery diseases, including a tubular braided mesh made of wires which are each helically wound about a longitudinal axis of the braided mesh and cross over and under one another. In an idle state, the braided mesh has a proximal cylindrical portion and a distal cylindrical portion which are connected to one another via a transition portion, wherein the proximal cylindrical portion has a different cross-sectional diameter and a different porosity compared to the distal cylindrical portion.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The disclosure relates to a medical kit for treating vascular diseases, including a tubular or sleeve-type insertion aid, a transport wire having a distal tip, and a stent having a wire mesh which consists of a plurality of wires that, at a proximal stent end define loops and, at a distal stent end, open wire ends. The stent is arranged on the transport wire and together with the transport wire inside the insertion aid. The distal stent end is closer to the distal tip of the transport wire than the proximal stent end.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
Stent including a mesh of wires having a radiopaque core material and a superelastic shell material and defining loops at a first stent end and open wire ends at a second stent end. The number of wire ends is double the number of loops; and more than 10 vol. %, in particular more than 20 vol. %, more particularly at least 25 vol. %, in particular at least 30 vol. % of each wire is constituted by the core material. The mesh includes (i) 48 wires, each having a wire diameter of 0.038 mm and an outer diameter of 3.65 mm or 4.15 mm or 4.65 mm; (ii) 52 wires each having a wire diameter of 0.042 mm and an outer diameter of 5.17 mm or 5.67 mm or 6.17 mm; or (iii) 64 wires each having a wire diameter of 0.046 mm or 0.05 mm and an outer diameter of 7.18 mm or 8.20 mm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The present invention relates to a medical device (10) for intravascular treatment, in particular a thrombectomy device (11), with an at least partially tubular mesh structure (12) which is convertible from a radially compressed state to a radially expanded state and has a multiplicity of cell-forming webs (13), wherein the mesh structure (12) comprises, at a distal end portion (14), at least two, in particular three or more pins (15) which are connected to the webs (13) and have a free end, wherein the pins (15), in a first longitudinal portion (16), are pressed flat onto one another at least in parts in order to fix the pin cross-sectional position, and/or the pins (15), in a second longitudinal portion (17), are form-fittingly connected to one another, particularly engaging in one another, in order to fix the pin longitudinal position.
A61B 17/221 - Calculus gripping devices in the form of loops or baskets
A61F 2/91 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
The disclosure relates to a medical implant for treating aneurysms, including a support structure, which has a compressible and expansible lattice structure lattice elements that define lattice openings, wherein the lattice structure is covered at least in part with an in particular electrospun membrane of fibres, which membrane includes at least one luminal functional layer and at least one abluminal protective layer, which each have pores, wherein the porosity of the functional layer is less than the porosity of the protective layer. The membrane is so configured that at least the pores of the functional layer open, as a result of a pressure gradient arising between a liquid pressure in an inner through channel of the support structure and a liquid pressure outside the protective layer, so as to increase the throughflow of liquid through the membrane.
The disclosure relates to a stent with a compressible and expandable mesh structure of webs which are interconnected by web connectors into one piece and define rhomboid cells, wherein each cell is defined by two straight webs and two S-shaped curved webs which connect the straight webs together, and wherein (i) in a non-operational state, the mesh structure has a fully expanded non-operational diameter Dexp which is between 3.0 mm and 5.0 mm, (ii) a ratio between a fully compressed diameter Dkomp of the mesh structure and the non-operational diameter Dexp of the mesh structure is between 1:7 and 1:12, and (iii) the webs have a web height, measured in a radial direction, which is at least 0.05 mm and at most 0.09 mm, so that the mesh structure has a radial force of at least 0.5 N, in particular at least 0.6 N, between the fully compressed diameter Dkomp and an operational diameter which is at most 90% of the non-operational diameter Dexp.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/958 - Inflatable balloons for placing stents or stent-grafts
16.
MEDICAL DEVICE FOR INTRAVASCULAR TREATMENT AND PRODUCTION METHOD
The invention relates to a medical device (10) for intravascular treatment, comprising at least two tubular and/or annular lattice structure segments (20a, 20b, 20c), which each comprise webs (15) interconnected in one piece, wherein the lattice structure segments (20a, 20b, 20c) each have at least one connecting web (30) on at least one longitudinal end (21a, 21b), wherein at least two lattice structure segments (20a, 20b, 20c) adjacent in the longitudinal direction (L) of the medical device (10) are interconnected in a form fitting manner at the connecting webs (30) and/or are integrally bonded to one another with the aid of a sleeve (40) encasing the connecting webs (30) at least in portions.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
17.
SYSTEM AND METHOD FOR BRAIDING A PATIENT-CUSTOMIZED STENT
The disclosure relates to a system for braiding a patient-specific adapted stent. The system includes at least one set with multiple braiding sleeves and a base carrier for receiving at least two braiding sleeves of the set, wherein the braiding sleeves each have an inner contour adapted to the outer contour of the base carrier, so that multiple braiding sleeves can be arranged in any order on the base carrier, in particular slid in any order onto the base carrier, to form a braiding mandrel, and wherein at least two braiding sleeves of the set have different outer contours from each another. Furthermore, the invention relates to a method for braiding a patient-specific adapted stent.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
18.
MEDICAL SYSTEM FOR TREATING STENOSIS IN INTRACRANIAL VESSELS
The disclosure relates to a medical system for treating stenosis in intracranial blood vessels including a compressible and self-expandable implant for covering the stenosis, said implant having a lattice structure, at least some sections of which are provided with a cover made of an electrospun fabric, wherein the fabric has irregularly sized pores, and a balloon catheter for dilating the stenosis and/or introducing the implant into the blood vessel.
The disclosure relates to a medical kit for the treatment of vascular malformations, in particular aneurysms and/or fistulas, having a permanently implantable covering device, in particular a stent, for covering the vascular malformation, the covering device having a tubular, self-expandable lattice structure and a covering made of an electrospun fabric, the covering being connected to the lattice structure and overlapping the lattice structure at least in part such that, when implanted, the covering is placed over the vascular malformation; and an embolisation means, which can be applied by a feed means in the implanted state for treatment of the vascular malformation, the covering forming a porous membrane which can be penetrated by the feed means for application of the embolisation means and which is designed to lie against the outer periphery of the feed means in the penetrated state.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a medical implant, more particularly stent, having a tubular lattice structure which can be transferred from a radially expanded compressed state to a radially compressed expanded state and has lattice elements that delimit the cells of the lattice structure and have an element surface. In order to enlarge the element surface of each lattice element a polymer nanostructure is distributed over the entire element surface of the lattice element and adheres to it, and an antithrombogenic coating is provided and extends across the lattice element structure surface enlarged by means of the polymer nanostructure. The invention also relates to a production method.
The invention relates to a medical kit for the treatment of aneurysms, including a main catheter and a cover device for temporarily covering as aneurysm, which cover device can be moved through the main catheter to a place of treatment. The cover device includes a self-expanding lattice structure that has a cylindrical portion, open at a distal end and at least partially provided with a cover, and a funnel-type portion that is permanently connected to a transport wire, movable inside the main catheter, and a total lateral area of which is not covered so that when the lattice structure is expanded, blood can flow through it in the direction of its longitudinal axis. The invention further relates to a medical system.
A61F 2/01 - Filters implantable into blood vessels
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
22.
MEDICAL SET FOR TREATING ANEURYSMS, PRODUCTION PROCESS, AND MEDICAL SYSTEM FOR TREATING ANEURYSMS
The invention relates to a medical set for treating aneurysms, including a main catheter and a covering device which can be moved through the main catheter to a treatment site and is intended to cover an aneurysm. The covering device is connected or can be connected to a transporting wire and includes a self-expandable grid structure made up of webs that are connected to one another in one piece and delimit inner cells and outer cells. The outer cells form at one longitudinal end of the grid structure a closed outer-cell ring, which is connected only on one side to inner cells. The grid structure is provided with a covering made of a fabric which has pores of irregular sizes, wherein at least one inner cell of the grid structure is at least partially, in particular mostly, free from the covering. A production process and a medical system are also provided.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a medical device for treating aneurysms, in particular a stent, including a compressible and expandable grid structure made up of grid elements. The grid structure has at least one closed cell ring which includes at most 12, in particular at most 10, in particular at most 8, in particular at most 6 cells directly adjacent to one another in a circumferential direction of the grid structure. The grid structure is provided at least in certain portions with a covering made of an electrospun fabric which has pores of irregular sizes. The covering includes over a surface area of 100 000 μm2 at least 10 pores which have a size of at least 15 μm2. The covering has a biocompatible, in particular antithrombogenic and/or endothelialization-promoting coating.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
xyy) and surrounds the structural material. The invention is characterised in that the mixed oxide layer has a layer thickness of at least 15 nm and is at least partially, in particular completely, coated by a top layer that has an antithrombogenically acting material. The invention also relates to a method for producing such an implant.
A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of bloodMaterials for such treatment
25.
STENT, IN PARTICULAR FOR TREATING CAROTID ARTERY DISEASES
The invention relates to a stent (10), in particular for treating carotid artery diseases, the stent comprising a tubular braided mesh made of wires (11) which are each helically wound about a longitudinal axis (Q) of the braided mesh and cross over and under one another, wherein, in an idle state, the braided mesh has a proximal cylindrical portion (A3) and a distal cylindrical portion (A1) which are connected to one another via a transition portion (A2), wherein the proximal cylindrical portion (A3) has a different cross-sectional diameter and a different porosity compared to the distal cylindrical portion (A1).
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a method for producing a stent, in which the following steps are carried out: a) providing image data of a blood vessel section to be treated, b) determining a diameter profile of the blood vessel section, c) determining a curvature profile and/or torsion profile of the blood vessel section, d) analysing the curvature profile and/or torsion profile and determining profile segments in which a predefined curvature limit value and/or torsion limit value is exceeded, e) forming a tool model by transferring the diameter profile to a linear axis, f) creating a braiding tool in the form of the tool model, g) braiding wires on the braiding tool to form the stent using a braiding machine, wherein at least one braiding parameter is adjusted in a section of the stent in which the curvature limit value and/or torsion limit value is exceeded.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
Stent comprising a mesh (10) consisting of wires (11), each having a radiopaque core material and a superelastic shell material and defines loops (14) at a first stent end (12) and open wire ends (15) at a second stent end (13), wherein: the number of wire ends (15) is double the number of loops (14); more than 10 vol.%, in particular more than 20 vol.%, more particularly at least 25 vol.%, in particular at least 30 vol.% of each wire (11) is constituted by the core material; the mesh (10) comprises - 48 wires (11), each having a wire diameter of 0.038 mm and an outer diameter of 3.65 mm or 4.15 mm or 4.65 mm; or - 52 wires (11) each having a wire diameter of 0.042 mm and an outer diameter of 5.17 mm or 5.67 mm or 6.17 mm; or - 64 wires (11) each having a wire diameter of 0.046 mm or 0.05 mm and an outer diameter of 7.18 mm or 8.20 mm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a medical kit for treating vascular diseases, the set comprising a tubular or sleeve-type insertion aid (10), a transport wire (20) having a distal tip (21), and a stent (30) having a wire mesh (37) which consists of a plurality of wires (36) that, at a proximal stent end (33) define loops (34, 35) and, at a distal stent end (31), open wire ends (32), the stent (30) being arranged on the transport wire (20) and together with the transport wire inside the insertion aid (10), and the distal stent end (31) is closer to the distal tip (21) of the transport wire (20) than the proximal stent end (33).
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
29.
INTRAVASCULAR FUNCTIONAL ELEMENT, SYSTEM HAVING A FUNCTIONAL ELEMENT, AND METHOD
The disclosure relates to an intravascular functional element, in particular an implant, more particularly a Stent, flow diverter, stent graft and intravascular occlusion device, having a radially self-expandable lattice structure which is tubular at least in some regions and which has a wire or a plurality of wires, wherein the wire/at least one of the wires includes a superelastic material, in particular a superelastic material of an alloy with the alloy elements nickel and titanium, wherein a mixed oxide layer is formed on the surface of the wire the wires with a layer thickness of 150 nm to 400 nm, in particular 200 nm to 350 nm, in particular 250 nm to 300 nm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a medical implant for treating aneurysms, comprising a support structure (1), which has a compressible and expansible lattice structure (10) of lattice elements that define lattice openings, wherein the lattice structure (10) is covered at least in part with an in particular electrospun membrane (2) of fibres, which membrane (2) comprises at least one luminal functional layer (4) and at least one abluminal protective layer (3), which each have pores, wherein the porosity of the functional layer (4) is less than the porosity of the protective layer (3). The invention is characterized in that the membrane (2) is so configured that at least the pores of the functional layer (4) open, as a result of a pressure gradient arising between a liquid pressure in an inner through-channel of the support structure (1) and a liquid pressure outside the protective layer (3), so as to increase the throughflow of liquid through the membrane (2).
The invention relates to a medical device, in particular a stent, having a radially self-expandable lattice structure (10) which is tubular at least in some sections and which is made of a single wire (11), which is interwoven with itself and which comprises a core material (11a) which is visible under X-ray and a superelastic jacket material (11b) and forms meshes (12) of the lattice structure (10). The invention is characterised in that a plurality of meshes (12) arranged directly adjacently in the circumferential direction of the lattice structure (10) form a mesh ring (13), and the lattice structure (10), in a fully self-expanded state, has an expansion diameter Dexp, the mesh ring (13) having a mesh number n, and the core material (11a) having a core diameter dKern, and the following being true for the core diameter dKern: dKern=f·(Dexp/n), with the following being true for a visibility factor f: 0.05≤f≤0.08.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61L 31/18 - Materials at least partially X-ray or laser opaque
The invention concerns a medical device, in particular a flow diverter, having a radially self-expandable lattice structure (10) which is tubular at least in some regions and which is composed of a plurality of interwoven individual wires (11) which form meshes (12) of the lattice structure (10), wherein at least some of the individual wires (11) have an X-ray visible core material (11a) and a superelastic mantle material (11b), wherein a plurality of directly adjacent meshes (12) in the circumferential direction of the lattice structure (10) form a mesh ring (13), wherein in a fully self-expanded state, the lattice structure (10) has an expansion diameter Dexp, the mesh ring (13) has a mesh number n, and the core material (11a) has a core diameter dcore, and wherein for the core diameter dcore, the following holds:
The invention concerns a medical device, in particular a flow diverter, having a radially self-expandable lattice structure (10) which is tubular at least in some regions and which is composed of a plurality of interwoven individual wires (11) which form meshes (12) of the lattice structure (10), wherein at least some of the individual wires (11) have an X-ray visible core material (11a) and a superelastic mantle material (11b), wherein a plurality of directly adjacent meshes (12) in the circumferential direction of the lattice structure (10) form a mesh ring (13), wherein in a fully self-expanded state, the lattice structure (10) has an expansion diameter Dexp, the mesh ring (13) has a mesh number n, and the core material (11a) has a core diameter dcore, and wherein for the core diameter dcore, the following holds:
dcore=f·(Dexp/n)
The invention concerns a medical device, in particular a flow diverter, having a radially self-expandable lattice structure (10) which is tubular at least in some regions and which is composed of a plurality of interwoven individual wires (11) which form meshes (12) of the lattice structure (10), wherein at least some of the individual wires (11) have an X-ray visible core material (11a) and a superelastic mantle material (11b), wherein a plurality of directly adjacent meshes (12) in the circumferential direction of the lattice structure (10) form a mesh ring (13), wherein in a fully self-expanded state, the lattice structure (10) has an expansion diameter Dexp, the mesh ring (13) has a mesh number n, and the core material (11a) has a core diameter dcore, and wherein for the core diameter dcore, the following holds:
dcore=f·(Dexp/n)
wherein the following holds for a visibility factor f:
The invention concerns a medical device, in particular a flow diverter, having a radially self-expandable lattice structure (10) which is tubular at least in some regions and which is composed of a plurality of interwoven individual wires (11) which form meshes (12) of the lattice structure (10), wherein at least some of the individual wires (11) have an X-ray visible core material (11a) and a superelastic mantle material (11b), wherein a plurality of directly adjacent meshes (12) in the circumferential direction of the lattice structure (10) form a mesh ring (13), wherein in a fully self-expanded state, the lattice structure (10) has an expansion diameter Dexp, the mesh ring (13) has a mesh number n, and the core material (11a) has a core diameter dcore, and wherein for the core diameter dcore, the following holds:
dcore=f·(Dexp/n)
wherein the following holds for a visibility factor f:
0.08≤f≤0.15
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
33.
MEDICAL DEVICE FOR INTRODUCING INTO A BODILY HOLLOW VISCUS, MEDICAL SET, AND PRODUCTION METHOD
A medical device for inserting into a hollow organ of the body, said medical device having a compressible and expandable lattice structure made of webs, which are integrally connected to each other by web connectors and which bound closed cells of the lattice structure, wherein the web connectors each have a connector axis extending between two cells which, in a longitudinal direction of the lattice structure, are adjacent to each other. During the transition of the lattice structure from the production state to a compressed state, the web connectors rotate in such a way that an angle between the connector axis and a longitudinal axis of the lattice structure changes, in particular increases, during the transition of the lattice structure from a completely expanded production state to a partially expanded intermediate state.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
34.
SYSTEM AND METHOD FOR BRAIDING A PATIENT-CUSTOMIZED STENT
The invention relates to a system for braiding a patient-customized stent (10), wherein the system comprises at least one set (20) with a plurality of braiding sleeves (21, 22, 23) and a base support (30) for receiving at least two braiding sleeves (21, 22, 23) of the set (20), wherein the braiding sleeves (21, 22, 23) each have an inner contour that is matched to the outer contour of the base support (30) so that a plurality of braiding sleeves (21, 22, 23) are arrangeable on the base support (30), in particular able to be pushed on the base support (30), in any sequence in order to form a braiding mandrel (40), and wherein at least two braiding sleeves (21, 22, 23) of the set (20) have different outer contours. Further, the invention relates to a method for braiding a patient-customized stent (10).
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
D04C 1/06 - Braid or lace serving particular purposes
The invention relates to a medical system for treating stenosis in intracranial blood vessels, comprising - a compressible and self-expandable implant (1) for covering the stenosis, said implant having a lattice structure (10), at least some sections of which are provided with a cover (40) made of an electrospun fabric, wherein the fabric has irregularly sized pores (41), and - a balloon catheter (60) for dilating the stenosis and/or introducing the implant (1) into the blood vessel.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/958 - Inflatable balloons for placing stents or stent-grafts
36.
MEDICAL KIT, MEDICAL SYSTEM, AND COVERING DEVICE FOR THE TREATMENT OF ANEURYSMS
The invention relates to a medical kit for the treatment of vascular malformations, in particular aneurysms and/or fistulas, having: a permanently implantable covering device (12), in particular a stent, for covering the vascular malformation, the covering device (12) having a tubular, self-expandable lattice structure (14) and a covering (20) made of an electrospun fabric, the covering (20) being connected to the lattice structure (14) and overlapping the lattice structure (14) at least in part such that, when implanted, the covering is placed over the vascular malformation; and an embolisation means (40), which can be applied by a feed means (44) in the implanted state for treatment of the vascular malformation, the covering (20) forming a porous membrane which can be penetrated by the feed means (44) for application of the embolisation means (40) and which is designed to lie against the outer periphery of the feed means (44) in the penetrated state.
A61F 2/91 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention relates to a medical device for use in human vessels, in particular in the carotid artery, comprising: a self-expandable mesh structure which at least partially forms a curved wall, and has, in a radially compressed state, a cross-sectional diameter of not more than 2.5 mm, wherein the mesh structure is formed of at least one mesh structural element which has a height that is no more than 200 μm, in particular no more than 150 μm, preferably no more than 70 μm, where the height is measurable along a diameter of the mesh structure, and wherein the mesh structure is at least partially formed of a nickel titanium alloy and is at least partially coated in fibrin.
The invention relates to a medical device for treating aneurysms, in particular a stent, comprising a compressible and expandable grid structure (10) made up of grid elements (11, 12, 13, 14), which has at least one closed cell ring (34), which comprises at most 12, in particular at most 10, in particular at most 8, in particular at most 6 cells (30) directly adjacent to one another in a circumferential direction of the grid structure (10), wherein the grid structure (10) is provided at least in certain portions with a covering (40) made of an electrospun fabric which has pores (41) of irregular sizes, wherein the covering (40) comprises over a surface area of 100 000 µm2 at least 10 pores (41) which have a size of at least 15 µm2, and wherein the covering (40) has a biocompatible, in particular antithrombogenic and/or endothelialization-promoting coating (45).
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
39.
MEDICAL KIT AND MEDICAL SYSTEM FOR THE TREATMENT OF ANEURYSMS
The invention relates to a medical kit (2) for the treatment of aneurysms (4), comprising a main catheter (8), a cover device (12) for temporarily covering an aneurysm (4), which cover device can be moved through the main catheter (8) to a place of treatment (10). The cover device (12) comprises a self-expanding lattice structure (14) that has a cylindrical portion (16), open at a distal end (18) and at least partially provided with a cover (20), and a funnel-type portion (22) that is permanently connected to a transport wire (26), movable inside the main catheter (8), and a total lateral area (27) of which is not covered so that when the lattice structure (14) is expanded, blood can flow through it in the direction of its longitudinal axis. The invention further relates to a medical system.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
40.
MEDICAL SET FOR TREATING ANEURYSMS, PRODUCTION PROCESS, AND MEDICAL SYSTEM FOR TREATING ANEURYSMS
The invention provides a medical set (2) for treating aneurysms (4), comprising a main catheter (8), a covering device (12), which can be moved through the main catheter (8) to a treatment site (10) and is intended for covering an aneurysm (4), wherein the covering device (12) is connected or can be connected to a transporting wire (15) and comprises a self-expandable grid structure (14) made up of webs (16) that are connected to one another in one piece and delimit inner cells (18) and outer cells (20), wherein the outer cells (20) form at one longitudinal end (22) of the grid structure (14) a closed outer-cell ring (24), which is connected only on one side to inner cells (18), characterized in that the grid structure (14) is provided with a covering (26) made of a fabric which has pores (28) of irregular sizes, wherein at least one inner cell (18) of the grid structure (14) is at least partially, in particular mostly, free from the covering. A production process and a medical system are also provided.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A medical device, having a body that is tubular at least in some sections. The body can be transferred from a compressed state into an expanded state and has a circumferential wall having at least one first lattice structure and one second lattice structure. The first lattice structure and the second lattice structure form separate layers of the circumferential wall, which are arranged coaxially one inside the other and connected to each other at least at points in such a way that the first lattice structure and the second lattice structure can be moved relative to each other at least in some sections. A system having such a device is also disclosed.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/852 - Two or more distinct overlapping stents
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention relates to an intravascular functional element, in particular an implant, more particularly a stent, flow diverter, stent graft and intravascular occlusion device, having a radially self-expandable lattice structure (12) which is tubular at least in some regions and which has a wire (10) or a plurality of wires (10), wherein the wire (10)/at least one of the wires (10) comprises a superelastic material, in particular a superelastic material of an alloy with the alloy elements nickel and titanium, wherein a mixed oxide layer is formed on the surface of the wire (10)/of the wires (10) with a layer thickness of 150 nm to 400 nm, in particular 200 nm to 350 nm, in particular 250 nm to 300 nm.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
The invention relates to a medical device for introducing into a bodily hollow viscus, in particular to a stent, comprising a compressible and expandable lattice structure (10) consisting of lattice elements (11, 12, 13, 14) having at least one ring of closed cells (34), said ring comprising a maximum 12, in particular a maximum 10, in particular a maximum 8, and in particular a maximum 6 cells (30) lying directly adjacent around the circumference of the lattice structure (10). The invention is characterised in that the lattice structure (10) is provided, at least in part, with a covering (40) of electrospun woven fabric with irregularly large pores (41), said covering (40) having at least 10 pores that have a size of at least 15 µm² over an area of 100,000 µm².
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention relates to a medical device for use in human vessels, in particular in the carotid artery, comprising: a self-expandable mesh structure which at least partially forms a curved wall, and has, in a radially compressed state, a cross- sectional diameter of not more than 2.5 mm, wherein the mesh structure is formed of at least one mesh structural element which has a height that is no more than 200 µm, in particular no more than 150 µm, preferably no more than 70 µm, where the height is measurable along a diameter of the mesh structure, and wherein the mesh structure is at least partially formed of a nickel titanium alloy and is at least partially coated in fibrin.
A61F 2/01 - Filters implantable into blood vessels
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
47.
MEDICAL CATHETER, MEDICAL SYSTEM AND METHOD FOR PRODUCING A MEDICAL CATHETER
The invention relates to a medical catheter having a catheter tube and at least one inner lumen (18), wherein a reinforcement element (10) is allocated to the catheter tube. The reinforcement element (10) comprises at least two reinforcement structures (11, 12), wherein a first reinforcement structure (11) is formed from at least one monofilament (16) and a second reinforcement structure (12) is formed from at least one multifilament bundle (17). The monofilament (16) and the multifilament bundle (17) are interwoven with each other. The monofilament (16) has a first winding direction and the multifilament bundle (17) has a second winding direction, wherein the first winding direction differs from the second winding direction. The invention further relates to a medical system and a method for producing a medical catheter.
A medical device, having a body that is tubular at least in some sections. The body can be transferred from a compressed state into an expanded state and has a circumferential wall having at least one first lattice structure and one second lattice structure. The first lattice structure and the second lattice structure form separate layers of the circumferential wall, which are arranged coaxially one inside the other and connected to each other at least at points in such a way that the first lattice structure and the second lattice structure can be moved relative to each other at least in some sections. A system having such a device is also disclosed.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61F 2/852 - Two or more distinct overlapping stents
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention relates to a medical device for inserting into a hollow organ of the body. The device has a compressible and expandable lattice structure made of webs, which are integrally connected to each other by web connectors and which bound closed cells of the lattice structure, wherein the web connectors each have a connector axis extending between two cells which, in a longitudinal direction of the lattice structure, are adjacent to each other. During the transition of the lattice structure from the production state to a compressed state, the web connectors rotate in such a way that an angle between the connector axis and a longitudinal axis of the lattice structure changes, in particular increases, during the transition of the lattice structure from a completely expanded production state to a partially expanded intermediate state.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A61F 2/91 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
A61B 17/221 - Calculus gripping devices in the form of loops or baskets
A61F 2/01 - Filters implantable into blood vessels
50.
Medical system for endovascular temperature control of blood, and medical catheter
A medical system for endovascular temperature control of blood and for recanalization of a blood vessel, the medical system having a catheter, a radially compressible treatment device, in particular a recanalization device, which, in the compressed state, is arranged to be longitudinally movable in the catheter and, by being released from the catheter, is radially expandable for the recanalization of the blood vessel, and a temperature control element for controlling the temperature of blood, wherein the treatment device, in particular the recanalization device, can be positioned distally with respect to the temperature control element in such a way that, during use, blood which is temperature-controlled by the temperature control element flows to the recanalization site in the blood vessel.
A61F 7/12 - Devices for heating or cooling internal body cavities
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/221 - Calculus gripping devices in the form of loops or baskets
A61F 2/86 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure
A61F 2/88 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
C23C 8/02 - Pretreatment of the material to be coated
C23C 8/52 - Solid state diffusion of only non-metal elements into metallic material surfacesChemical surface treatment of metallic material by reaction of the surface with a reactive gas, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using liquids, e.g. salt baths, liquid suspensions more than one element being applied in one step
A61L 31/14 - Materials characterised by their function or physical properties
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
52.
Intravascular functional element and system for such a functional element
2 and at least one nitride, especially titanium oxynitride and/or titanium nitride, is formed on the surface of the wire or on the surface of the wires (10)/of the wires (10), wherein the grid structure forms cells of mutually crossing wires (10) or wire segments of the wire (10) in longitudinal direction and in circumferential direction respectively and in circumferential direction there are disposed at least 6 cells, especially at least 12 cells, especially at least 16 cells, especially at least 24 cells, especially at least 36 cells, especially at least 48 cells.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
53.
Electrode for medical applications, system having an electrode, and method for producing an electrode
An electrode for medical applications for neuromodulation and/or nerve stimulation and/or neurological signal detection, which electrode can be compressed and expanded in order to insert same into a hollow organ of a body and is or can be coupled to a current supply. The electrode has a compressible and expandable lattice structure including lattice webs, which form cells, wherein the lattice structure is or can be coupled to the current supply and forms at least one electrically conductive region and at least one electrically insulated region.
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/88 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
A61F 2/91 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
A method for producing a medical functional element having a self-supporting lattice structure which has interconnected webs. The method applies a first layer to the substrate layer, the first layer is structured by an etching process, the structured first layer is under-cut of a wet chemical etching process acting on the substrate layer, the substrate layer is removed in order to form the self-supporting lattice structure, a web constructional layer is applied to the first layer. The method is distinguished by the forming the first web attachment layer which has a smaller layer thickness than the web constructional layer and is intimately bonded to the web constructional layer in such a way that the web attachment layer, together with the web constructional layer, forms the webs of the self-supporting lattice structure.
C03C 15/00 - Surface treatment of glass, not in the form of fibres or filaments, by etching
B44C 1/22 - Removing surface-material, e.g. by engraving, by etching
H01L 21/027 - Making masks on semiconductor bodies for further photolithographic processing, not provided for in group or
H01L 21/768 - Applying interconnections to be used for carrying current between separate components within a device
H05K 3/04 - Apparatus or processes for manufacturing printed circuits in which the conductive material is applied to the surface of the insulating support and is thereafter removed from such areas of the surface which are not intended for current conducting or shielding the conductive material being removed mechanically, e.g. by punching
patents
