There are provided methods of manufacturing microfluidic chips, the methods comprising forming one or more fluid channels in a first substrate layer, providing a second substrate layer in contact with the first substrate layer, and bonding the first substrate layer and second substrate layer together to form a wafer, and dividing the wafer to form the microfluidic chip, wherein dividing the wafer to form the microfluidic chip comprises irradiating the wafer with a laser, wherein the laser is focused inside the wafer to create one or more internal regions of laser modified material within the wafer wherein the one or more internal regions of laser modified material extend in an intended fracture plane defining a desired arrangement of the outlet surface of the microfluidic chip and applying mechanical stress to the wafer to fracture the wafer along the intended fracture plane.
B05B 1/26 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectorsBreaking-up the discharged liquid or other fluent material by impinging jets
B23K 26/53 - Working by transmitting the laser beam through or within the workpiece for modifying or reforming the material inside the workpiece, e.g. for producing break initiation cracks
B81C 1/00 - Manufacture or treatment of devices or systems in or on a substrate
A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
A sensing system for determining the location and orientation of an object which comprises a magnetic tag. The sensing system comprises selection coils and interrogation coils. The selection coils are arranged to generate a spatially varying DC magnetic field from which the location of the tag can be determined in use. At least some of the interrogation coils are arranged to generate one or more AC magnetic fields and at least some of the interrogation coils are arranged to receive harmonics, intermodulation products or time dependent variations of the AC magnetic fields, from which the orientation of the tag is determined in use.
G01B 7/30 - Measuring arrangements characterised by the use of electric or magnetic techniques for measuring angles or tapersMeasuring arrangements characterised by the use of electric or magnetic techniques for testing the alignment of axes
G01B 7/00 - Measuring arrangements characterised by the use of electric or magnetic techniques
G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux
3.
PRESSURE CONTROL SYSTEM, DEVICE AND METHOD FOR OPENING AN AIRWAY
The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.
09 - Scientific and electric apparatus and instruments
38 - Telecommunications services
Goods & Services
(1) Communications apparatus (terminals for communication via satellite networks); communication terminals; autonomous navigation systems; satellites; intercommunication satellites; satellite navigational instruments and systems; satellite communication apparatus. (1) Providing access to satellite communications networks; communications by mobile phones; communications by computer terminals; paging services; radio communications; telecommunication via computer terminals, telematics, satellites and radio; communication via satellite; consultancy services relating to telecommunications and telecommunications technology.
5.
CARTRIDGE AND SYSTEM FOR STORING AND DISPENSING LIQUID
A cartridge and system for storing and dispensing liquid medicament, the cartridge comprising an outer container, a collapsible bag arranged within the outer container and configured to store liquid medicament. The cartridge further comprises a cap configured to close the outer container and the collapsible bag, wherein the cap comprises a medicament dispensing channel extending through the cap to the collapsible bag and one or more pressure equalisation channels extending through the cap to an intermediate cavity between the outer container and the collapsible bag and a seal configured to close the medicament dispensing channel and the one or more pressure equalisation channels. The cap is configured such that when the seal is broken, the contents of the collapsible bag may be dispensed and gas from the exterior of the cartridge may enter the intermediate cavity through the pressure equalisation channels.
The disclosure provides an atomiser arranged in use to atomise a fluid, the atomiser comprising a vessel for accommodating the fluid; a plate comprising a perforate region and a support region, wherein at least one perforation is provided in the perforate region, and wherein the perforate region has a lower thickness than that of the support region; and an actuator arranged in use to impart a pressure disturbance on the fluid, wherein the actuator is disposed at least in part in the vessel, and wherein the pressure disturbance ejects the fluid through the at least one perforation, thereby atomising the fluid. The disclosure provides an associated method of atomising a fluid.
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
B05B 17/00 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of the opened compartment.
A biological processing apparatus, comprising: a plurality of modular containers, each container comprising: a bottom housing comprising an internal cavity, a top housing attached to the bottom housing, the top housing comprising a fluid opening, thereby to provide a fluid connection from the top housing to the cavity of the bottom housing, wherein the fluid opening is configured to allow transfer of fluid to and from the container; and a biological processing cartridge comprising: a frame, and a plurality of slots arranged on the frame, each slot releasably retaining a respective one of the containers; wherein each of the modular containers and each of the slots comprise corresponding engagement components to enable any of the modular containers to be retained in any of the slots, and wherein at least two of the modular containers have a bottom housing that is different to each other.
The invention relates to a pathogen testing system that can analyses multiple samples at once in order to provide guidance on the presence of an infection in a given environment. This reduces the number of individual tests that are needed and provides enhanced confidence as to the levels of pathogen in a given environment.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
A suturing tool for an endoscope or a laparoscope, the tool comprising: a symmetric suturing needle comprising a point at each end of the needle; and a pair of jaws for suturing a target object between the jaws, each jaw comprising a needle holder for holding the suturing needle, the pair of jaws being configured to move between an open jaw position and a closed jaw position, wherein each needle holder comprises a moveable locking element configured to move between a closed lock position in which the suturing needle is held by the needle holder and an open lock position at which the suturing needle is released by the needle holder, and each needle holder further comprises a resilient control mechanism configured to switch the locking element between the closed lock position and the open lock position.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61B 17/06 - NeedlesHolders or packages for needles or suture materials
An insert for a micro-nozzle (10), and a micro-nozzle (10) comprising such insert. The insert comprises a microfabricated fluidic chip (1) having an inlet, an outlet and one or more microfluidic channels connecting the inlet and outlet and an overmould casing (2) overmoulded around the fluidic chip (1) so as to substantially encase the fluidic chip (1), and comprising an inlet in fluid communication with the inlet of the chip and an outlet in fluid communication with the outlet of the chip.
B05B 1/16 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with multiple outlet openingsNozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with strainers in or outside the outlet opening having selectively-effective outlets
B05B 15/18 - Arrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for improving resistance to wear, e.g. inserts or coatingsArrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for indicating wearArrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for handling or replacing worn parts
B05B 15/40 - Filters located upstream of the spraying outlets
12.
OPTICAL ANALYSIS SYSTEM FOR ANALYSING BIOLOGICAL PROCESSES
An optical system (31) for analysing biological processes comprising: a biological process vessel (33) comprising a chamber and an optical interface element (34) for optically coupling the chamber to an optical emitter, a wavelength discrimination component, and an optical detector when a biological process fluid in the chamber is being analysed, the optical interface element being configured to couple light in the mid-infrared range; an optical emitter (351) configured to emit light in the mid-infrared range; an optical detector (353) configured to detect light in the mid-infrared range; a wavelength discrimination component (352); an alignment component (42) for aligning the optical emitter, optical detector, and wavelength discrimination component with the optical interface element; and a processor (354) configured to: receive outputs from the optical detector; and process the received outputs from the optical detector to provide an indication of the constituents of a biological process fluid in the chamber.
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
There is described a method of spatially resolved cellular profiling for integrating profiling data of a cell or cell-derived material with spatial positioning of the cell or cell- derived material, the method comprising: contacting the surface of a cell or tissue sample with a population of particles, wherein the particles comprise at least 3 distinguishable subpopulations, wherein each of the at least 3 distinguishable subpopulations has a distinguishable trait that can be determined by imaging, and wherein the particles comprise binding molecules that bind to target biomolecules from the sample; imaging the sample and the population of particles; profiling the particles to generate profiling data corresponding to each particle; and providing a virtual map of the spatially resolved profiling data with respect to the sample image.
A receiver for a lidar system. The receiver comprises a monolithic block of optically transmissive material, the block shaped to define a planar light receiving surface, a first reflective surface and a second reflective surface positioned adjacent to the light receiving surface. The surfaces are positioned such that light from a distant on-axis source passing through the light receiving surface passes through the block to the first reflective surface and is reflected thereby towards the second reflective surface and in turn reflected thereby to pass through a receiving aperture formed in the first reflective surface and to come to a focus at or after the receiving aperture.
There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises: a fluid flow channel for receiving, in use, the flow of fluid; a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid; a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.
There is provided sample analysis cartridges comprising a housing defining a reaction chamber configured to receive a sample, a dry reagent storage chamber, and a fluid reagent storage chamber, and a reagent supply mechanism for selectively supplying reagent from the dry and fluid storage chambers during an analysis, wherein the dry reagent storage chamber comprises a liner formed from a material having a lower fluid permeability than the material from which the housing is formed.
09 - Scientific and electric apparatus and instruments
38 - Telecommunications services
Goods & Services
Communications apparatus (terminals for communication via
satellite networks); communication terminals; autonomous
navigation systems; satellites; intercommunication
satellites; satellite navigational instruments and systems;
satellite communication apparatus. Providing access to satellite communications networks;
communications by mobile phones; communications by computer
terminals; paging services; radio communications;
telecommunication via computer terminals, telematics,
satellites and radio; communication via satellite;
consultancy services relating to telecommunications and
telecommunications technology.
There are provided sample analysis cartridges, and methods and systems using such sample analysis cartridges, wherein the sample analysis cartridges comprise a reaction chamber configured to receive a sample; a film defining at least a portion of a face of the reaction chamber; an inlet port fluidly connected to an inlet of the reaction chamber and an outlet port fluidly connected to an outlet of the reaction chamber; and an air reservoir fluidly connected to the reaction chamber; the inlet port, outlet port and air reservoir arranged such that, as the reaction chamber is filled with fluid through the inlet port, gas within the reaction chamber may escape the cartridge through the outlet port whilst gas within the air reservoir is retained; the inlet port, outlet port and air reservoir being further arranged such that such that, if the inlet and outlet ports are sealed, gas within the air reservoir applies pressure on the contents of the reaction chamber.
An electrochemical assembly, comprising: a plurality of electrochemical cells arranged to form an electrochemical stack having a first end and a second end; a first endcap disposed at the first end of the electrochemical stack, and a second endcap disposed at the second end of the electrochemical stack, and at least one of the endcaps being arranged to provide a fluidic connection to the electrochemical stack; wherein the first and second endcaps are secured to the electrochemical stack by a fibre-reinforced casing that extends around at least a portion of the electrochemical stack and at least a portion of each endcap such that a fluidic seal is formed between the electrochemical stack and each endcap.
09 - Scientific and electric apparatus and instruments
Goods & Services
Providing access to satellite communications networks; communications by mobile phones; communications by computer terminals; paging services; radio communications; telecommunication services in the nature of communication via computer terminals, telematics, satellites and radio; telecommunication services in the nature of secure datalinking between vehicles, remote operators and air traffic control via computer terminals, telematics, satellites and radio; communication via satellite; consultancy services relating to telecommunications Communications apparatus in the nature of computer terminals for communication via satellite networks; communication terminals in the nature of satellite terminals, telephone terminals, computer terminals, printer terminals, fax machine terminals, and radio terminals; autonomous navigation systems in the nature of global position systems (GPS) for use by autonomous vehicles; satellites; intercommunication satellites; satellite navigational instruments and systems in the nature of global positioning systems (GPS); satellite communication apparatus, namely, satellite amplifiers, satellite antennas, satellite block upconverters, and satellite terminals
An electroporation apparatus is disclosed, comprising: an electroporation channel for carrying cells in a liquid, the electroporation channel comprising: a first inlet arranged to introduce the cells and a first supply of liquid into the electroporation channel, an outlet arranged to receive the cells from the electroporation channel, and a second inlet arranged to introduce a second supply of liquid into the electroporation channel, the second inlet being located between the first inlet and the outlet; wherein the electroporation apparatus further comprises a first electrode which is configured to be electrically connected to the electroporation channel via the first inlet or the outlet and a second electrode which is configured to be electrically connected to the electroporation channel via the second inlet; and wherein the first and second electrodes are configured to provide a potential difference between the second inlet and the first inlet, or between the second inlet and the outlet, such that, in use, an electric field is generated in, and substantially parallel to, the electroporation channel.
A computer-implemented method for controlling an endoscope having a flexible tubular body, the method comprising: deploying an anchor to stabilise at least a part of the flexible tubular body; and performing active image stabilisation to stabilise the position of a camera at a distal end of the endoscope.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
There is provided a method of detecting the presence of a nucleic acid target sequence in which two oligonucleotides are used to forma three-way junction with the target sequence to allow detection of the target sequence. Alternatively, three oligonucleotides can be used to form a four-way junction with the target sequence to allow detection of the target sequence.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
21 - HouseHold or kitchen utensils, containers and materials; glassware; porcelain; earthenware
34 - Tobacco; smokers' articles
35 - Advertising and business services
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
45 - Legal and security services; personal services for individuals.
Goods & Services
Pumps for aerosols; aerosol filling machines; capping machines for aerosols. Scientific, photographic, optical, weighing, measuring and teaching apparatus and instruments; electronic control apparatus and instruments; electronic communication apparatus and instruments; electronic apparatus and instruments for processing, storing and monitoring data; diagnostic instrumentation; laser systems; light guides; optical apparatus and instruments; electronic apparatus, devices and instruments for sourcing, detecting and controlling light; digital printers; printers; sensors; apparatus for recording, transmission or reproduction of sound or images; magnetic data carriers, recording discs; computers; computer software; computer systems; 3D and graphics software; modelling software; data processing apparatus; battery chargers for electronic cigarettes; USB chargers for electronic cigarettes. Surgical, medical, dental and veterinary apparatus and instruments; inhalers; drug delivery apparatus; diagnostic apparatus; lasers for medical purposes. Aerosol dispensers for cosmetic applications; aerosol dispensers for industrial applications. Electronic cigarettes; holders for electronic cigarettes; cases for electronic cigarettes; liquid for electronic cigarettes; cartridges for electronic cigarettes; liquid nicotine solutions; flavourings, other than essential oils, for use in electronic cigarettes; personal vaporisers and flavourings and solutions therefor. Business management and consultancy services; management assistance; business research services; business advisory services relating to product development. Printing services. Computer software services; computer consultancy; updating, design and maintenance of computer software; engineering and design services and consultancy; healthcare, pharmaceutical and medical research services; drug discovery services; scientific and pharmaceutical research services; research and development of drug delivery processes; development of new products; product design and development; product development consultation; product research and development; information and professional consultancy relating to all the aforesaid services. Intellectual property management; management of copyright, industrial property and intellectual property rights in relation to technological research and development; licensing of intellectual property and technology.
An insert for a micro-nozzle, and a micro-nozzle comprising such insert. The insert comprises a microfabricated fluidic chip having an inlet, an outlet and one or more microfluidic channels connecting the inlet and outlet and an overmould casing overmoulded around the fluidic chip so as to substantially encase the fluidic chip, and comprising an inlet in fluid communication with the inlet of the chip and an outlet in fluid communication with the outlet of the chip.
B05B 1/02 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops
B05B 15/40 - Filters located upstream of the spraying outlets
A cap and seal system for a liquid medicament container. The system comprises a cap formed from a substantially rigid material and has a retention component integrally formed therewith. A seal is formed from a material which is less hard than the cap and positioned within the cap such that, when the retaining component retains the cap on a container in use the seal is positioned such that it forms a fluid tight seal between the cap and the container. A recess is formed in the seal through which a liquid outlet channel can pass in use to access the contents of the container via the cap and the seal.
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry applys an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
G06F 21/75 - Protecting specific internal or peripheral components, in which the protection of a component leads to protection of the entire computer to assure secure computing or processing of information by inhibiting the analysis of circuitry or operation, e.g. to counteract reverse engineering
A suturing tool for an endoscope or a laparoscope, the tool comprising: a symmetric suturing needle comprising a point at each end of the needle; and a pair of jaws for suturing a target object between the jaws, each jaw comprising a needle holder for holding the suturing needle, the pair of jaws being configured to move between an open jaw position and a closed jaw position, wherein each needle holder comprises a moveable locking element configured to move between a closed lock position in which the suturing needle is held by the needle holder and an open lock position at which the suturing needle is released by the needle holder, and each needle holder further comprises a resilient control mechanism configured to switch the locking element between the closed lock position and the open lock position.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A unit verification method to be performed on a unit under test (UUT) comprises connecting a verification device to the UUT. The verification device applies a set of challenge signals to the UUT and then measures the responses of the UUT to the challenge signals. The responses of the UUT are based on the challenge signals and the physical properties of the UUT. A registration key is generated based on the measured responses and is stored. The registration key is unique to the UUT.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry is configured for applying an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device. The media comprises a plurality of interactive regions, the interactive regions having an electrical and/or magnetic response characteristic which is permanently altered in response to a predetermined environmental event, and the identifying response is altered with the response characteristic.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
G06F 21/75 - Protecting specific internal or peripheral components, in which the protection of a component leads to protection of the entire computer to assure secure computing or processing of information by inhibiting the analysis of circuitry or operation, e.g. to counteract reverse engineering
An insert for a micro-nozzle (10), and a micro-nozzle (10) comprising such insert. The insert comprises a microfabricated fluidic chip (1) having an inlet, an outlet and one or more microfluidic channels connecting the inlet and outlet and an overmould casing (2) overmoulded around the fluidic chip (1) so as to substantially encase the fluidic chip (1), and comprising an inlet in fluid communication with the inlet of the chip and an outlet in fluid communication with the outlet of the chip.
B05B 15/18 - Arrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for improving resistance to wear, e.g. inserts or coatingsArrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for indicating wearArrangements for preventing or controlling structural damage to spraying apparatus or its outlets, e.g. for breaking at desired placesArrangements for handling or replacing damaged parts for handling or replacing worn parts
B05B 1/10 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops in the form of a fine jet, e.g. for use in wind-screen washers
A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
B05B 15/40 - Filters located upstream of the spraying outlets
B05B 1/14 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with multiple outlet openingsNozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with strainers in or outside the outlet opening
An optical system (31) for analysing biological processes comprising: a biological process vessel (33) comprising a chamber and an optical interface element (34) for optically coupling the chamber to an optical emitter, a wavelength discrimination component, and an optical detector when a biological process fluid in the chamber is being analysed, the optical interface element being configured to couple light in the mid-infrared range; an optical emitter (351) configured to emit light in the mid-infrared range; an optical detector (353) configured to detect light in the mid-infrared range; a wavelength discrimination component (352); an alignment component (42) for aligning the optical emitter, optical detector, and wavelength discrimination component with the optical interface element; and a processor (354) configured to: receive outputs from the optical detector; and process the received outputs from the optical detector to provide an indication of the constituents of a biological process fluid in the chamber.
G01N 21/43 - RefractivityPhase-affecting properties, e.g. optical path length by measuring critical angle
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
A medicament delivery device for dispensing discrete doses of medicament comprises: first and second medicament carriers each comprising said doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer; first and second opening mechanisms each arranged to handle a respective one of the first and second medicament carriers and to open each compartment of the respective medicament carrier by separating the sealing layer from the carrier strip as the medicament carrier is advanced through the device; a take-up spool arranged to wind the separated sealing layers thereon such as to maintain the separated sealing layers in tension, each separated sealing layer having a path of travel between a respective one of the first and second opening mechanisms and the take-up spool; and a tension control element in contact with each of the separated sealing layers, wherein at least a part of the tension control element is arranged to be movable by a biasing force, which is exerted on the tension control element by the separated sealing layers as a result of any inequality in the tensions of the separated sealing layers wound by the take-up spool, to alter the length of the path of travel of each separated sealing layer so as to substantially equalise the tensions in the separated sealing layers.
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors and a plurality of temperature compensation particles are arranged throughout the media, where the temperature compensation particles have a temperature coefficient selected such that they compensate for temperature-related effects in the PUF device by making the permittivity and/or permeability of the media substantially temperature independent. Circuitry applies an electrical challenge signal to at least one or the conductors and receives an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H01L 23/00 - Details of semiconductor or other solid state devices
35.
Environmentally dependent physically unclonable function device
A physically unclonable function (PUF) comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least of portion of each of the conductors and further defines at least one cavity, where the cavity is structured to provide the device with an environmentally dependent characteristic. Circuitry applies an electrical challenge signal to at least one of the conductors and receives an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H03K 19/003 - Modifications for increasing the reliability
H03K 19/17768 - Structural details of configuration resources for security
A physically unclonable function (PUF) device comprises a plurality of optical fibres, at least some of which are arranged such that they are optically coupled. A media surround at least a portion of the optical fibres and at least one light source is configured to transmit light through one or more of the optical fibres. There is provided at least one light sensor configured to receive the transmitted light from one or more of the optical fibres and provide an output. Circuitry applies a challenge signal to at least one of the fibres using at least one light source and receives the output from the at least one light sensor, using the output to generate an identifying response to the challenge signal. The fibres are arranged such that the identifying response is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
An endoscope is provided comprising: a plurality of sequentially arranged segments; wherein each segment of the plurality of segments is rotatably connected to an adjacent first segment about a first axis, and rotatably connected to an adjacent second segment about a second axis; wherein the first axis is angularly offset from the second axis by a segment offset angle that is less than 90°. By providing the endoscope in this manner, control of the endoscope may be improved and hysteresis reduced.
A phased array antenna comprises an array of reflective cells, each cell being defined by a wall positioned within the array the wall arranged to define a waveguide, and having a moveable reflector positioned within the wall. Each reflector is arranged such that it is not in electrical contact with its respective wall and such that, in use it can be moved to tune the antenna. A feed and subreflector are positioned within the array and arranged to transmit and/or receive electromagnetic signals to and/or from the array.
H01Q 3/20 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system using mechanical relative movement between primary active elements and secondary devices of antennas or antenna systems for varying relative position of primary active element and a reflecting device wherein the primary active element is fixed and the reflecting device is movable
H01Q 19/19 - Combinations of primary active antenna elements and units with secondary devices, e.g. with quasi-optical devices, for giving the antenna a desired directional characteristic using reflecting surfaces having two or more spaced reflecting surfaces comprising one main concave reflecting surface associated with an auxiliary reflecting surface
A receiver for a lidar system. The receiver comprises a monolithic block of optically transmissive material, the block shaped to define a planar light receiving surface, a first reflective surface and a second reflective surface positioned adjacent to the light receiving surface. The surfaces are positioned such that light from a distant on-axis source passing through the light receiving surface passes through the block to the first reflective surface and is reflected thereby towards the second reflective surface and in turn reflected thereby to pass through a receiving aperture formed in the first reflective surface and to come to a focus at or after the receiving aperture.
G01S 7/481 - Constructional features, e.g. arrangements of optical elements
G02B 13/02 - Telephoto objectives, i.e. systems of the type + – in which the distance from the front vertex to the image plane is less than the equivalent focal length
The invention relates to a pathogen testing system that can analyses multiple samples at once in order to provide guidance on the presence of an infection in a given environment. This reduces the number of individual tests that are needed and provides enhanced confidence as to the levels of pathogen in a given environment.
There is provided sample analysis cartridges comprising a housing defining a reaction chamber configured to receive a sample, a dry reagent storage chamber, and a fluid reagent storage chamber, and a reagent supply mechanism for selectively supplying reagent from the dry and fluid storage chambers during an analysis, wherein the dry reagent storage chamber comprises a liner formed from a material having a lower fluid permeability than the material from which the housing is formed.
There is provided sample analysis cartridges comprising a housing defining a reaction chamber configured to receive a sample, a dry reagent storage chamber, and a fluid reagent storage chamber, and a reagent supply mechanism for selectively supplying reagent from the dry and fluid storage chambers during an analysis, wherein the dry reagent storage chamber comprises a liner formed from a material having a lower fluid permeability than the material from which the housing is formed.
There are provided sample analysis cartridges, and methods and systems using such sample analysis cartridges, wherein the sample analysis cartridges comprise a reaction chamber configured to receive a sample; a film defining at least a portion of a face of the reaction chamber; an inlet port fluidly connected to an inlet of the reaction chamber and an outlet port fluidly connected to an outlet of the reaction chamber; and an air reservoir fluidly connected to the reaction chamber; the inlet port, outlet port and air reservoir arranged such that, as the reaction chamber is filled with fluid through the inlet port, gas within the reaction chamber may escape the cartridge through the outlet port whilst gas within the air reservoir is retained; the inlet port, outlet port and air reservoir being further arranged such that such that, if the inlet and outlet ports are sealed, gas within the air reservoir applies pressure on the contents of the reaction chamber.
There are provided sample analysis cartridges, and methods and systems using such sample analysis cartridges, wherein the sample analysis cartridges comprise a reaction chamber configured to receive a sample; a film defining at least a portion of a face of the reaction chamber; an inlet port fluidly connected to an inlet of the reaction chamber and an outlet port fluidly connected to an outlet of the reaction chamber; and an air reservoir fluidly connected to the reaction chamber; the inlet port, outlet port and air reservoir arranged such that, as the reaction chamber is filled with fluid through the inlet port, gas within the reaction chamber may escape the cartridge through the outlet port whilst gas within the air reservoir is retained; the inlet port, outlet port and air reservoir being further arranged such that such that, if the inlet and outlet ports are sealed, gas within the air reservoir applies pressure on the contents of the reaction chamber.
A liquid droplet production apparatus comprising a perforate membrane and an actuator. The actuator is configured to vibrate the perforate membrane such that a liquid in contact with the perforate membrane during use is caused to pass through at least one aperture of the perforate membrane and to be ejected as liquid droplets from the perforate membrane. The perforate membrane includes one or more stiffening structures for increasing the stiffness of the perforate membrane, the one or more stiffening structures each being defined by a local transverse deformation of the perforate membrane. A removable cartridge, a perforate membrane, an actuator assembly for use in such a liquid droplet delivery apparatus, and a method of manufacturing a perforate membrane for such a liquid droplet apparatus.
B05B 17/00 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
There is provided a camera for an endoscope. The camera comprises: a single sensor chip only; a first optic and second optic, each of the first optic and the second optic being arranged in use to direct light incident on the respective optic on to the sensor chip; and a barrier arranged in use to separate light being directed on to the sensor chip from each optic from light being directed on to the sensor chip from the other optic.
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
G02B 23/24 - Instruments for viewing the inside of hollow bodies, e.g. fibrescopes
A computer-implemented method for controlling an endoscope having a flexible tubular body, the method comprising: deploying an anchor to stabilise at least a part of the flexible tubular body; and performing active image stabilisation to stabilise the position of a camera at a distal end of the endoscope.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A cartridge for an aerosol delivery system. The cartridge includes a fluid reservoir including a first reservoir portion, a second reservoir portion, and at least one liquid barrier configured to separate the first and second reservoir portions. The first and second reservoir portions have respective first and second openings at a first end of the cartridge. The cartridge further includes a perforate membrane located at the first end of the cartridge and over the first and second openings. The first and second openings are configured to supply first and second liquids to a first side of the perforate membrane during use and the perforate membrane comprises a plurality of apertures configured to eject one or both of the first and second liquids from a second side of the perforate membrane in the form of liquid droplets when the perforate membrane is vibrated. An aerosol delivery system includes the cartridge.
A micro-nozzle with an integrated filter structure for receiving fluids at pressures between 0.1 MPa to 50 MPa, comprising: at least one fluid inlet, a fluid outlet comprising at least one orifice, a primary filter structure positioned downstream from the at least one fluid inlet and arranged to provide statistical filtration of fluid passing therethrough.
B05B 15/40 - Filters located upstream of the spraying outlets
B01D 29/01 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with flat filtering elements
B01D 29/50 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
An aerosol delivery system includes a perforate membrane comprising a plurality of apertures, as well as a fluid reservoir reservoir in fluid communication with a first side of the perforate membrane and actuation means configured to vibrate the perforate membrane to cause a liquid in the fluid reservoir during use to be ejected as liquid droplets from a second side of the perforate membrane. The plurality of apertures comprises first and second arrays of apertures of first and second configurations which are grouped together in first and second discrete regions of the perforate membrane. The fluid reservoir includes first and second reservoir portions and a liquid barrier by which the first and second reservoir portions are separated. A removable cartridge for an aerosol delivery system.
A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of said opened compartment.
A disposable cartridge for processing a biological fluid sample, the cartridge comprising: a sample holder configured to hold a collection tube containing the sample; an extractor configured to engage with the collection tube to transfer the sample from the collection tube to the cartridge; and a sample processor for processing the sample.
A device for releasing discrete doses of medicament carried in a plurality of spaced-apart compartments on a medicament carrier, each compartment being arranged in a carrier strip and sealed by a sealing layer, the device comprising: a release mechanism arranged to engage between the carrier strip and the sealing layer so as to unseal at least a portion of the compartment and expose the medicament dose contained therein, wherein the release mechanism preferably covers said exposed compartment in place of the sealing layer.
An insert for a micro-nozzle, and a micro-nozzle comprising such insert. The insert comprises a microfabricated fluidic chip having an inlet, an outlet and one or more microfluidic channels connecting the inlet and outlet and an overmould casing overmoulded around the fluidic chip so as to substantially encase the fluidic chip, and comprising an inlet in fluid communication with the inlet of the chip and an outlet in fluid communication with the outlet of the chip.
A droplet dispenser comprises a chamber (3) with a fluid inlet valve (2) and a fluid outlet valve (4). The chamber (3) is arranged such that the volume of the chamber may be varied in use to cause fluid to be alternately drawn in to the chamber (3) through the inlet valve (2) then subsequently expelled from the chamber through the outlet valve (4) to dispense a droplet. The droplet dispenser is capable of dispensing from an open reservoir and one may change the dispensed drop volume simply and easily. The droplet dispenser can also handle liquids which are normally seen as difficult to dispense, such as cyanoacrylate adhesives.
B05C 5/02 - Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work from an outlet device in contact, or almost in contact, with the work
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
G01F 11/08 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type
There is provided a sample preparation device comprising a sample preparation vessel and a bead manipulation mechanism for manipulating sample preparation beads in the vessel. The bead manipulation mechanism comprises: one or more magnets arranged to produce a magnetic field for manipulating, in use, one or more beads in the vessel. Each magnet is attached to a support frame by a biasing support arranged to support the magnet in contact against an outer surface of the vessel such that the magnet maintains contact with the vessel during relative movement between the magnets and the vessel.
A counting mechanism (100) for a dispenser comprising: a first and a second housing part (110, 120) that are rotatable relative to each other; and a counting ring (130) disposed between the housing parts. The first housing part has a protrusion (111) which abuts the counting ring, holding a portion of the counting ring in contact with the second housing part. The relative rotation of the housing parts causes the protrusion to slide against the surface of the counting ring to drive a rolling movement of the counting ring around the circumference of the second housing part, such that a predefined rotation of the housing parts produces an incremental rotational displacement between the counting ring and second housing part to record a count. The counting mechanism provides a large gear reduction ratio in a compact form which is straightforward to manufacture and provides an accurate and reliable record of counts.
G06M 3/02 - Counters with additional facilities for performing an operation at a predetermined value of the count, e.g. arresting a machine
G06M 1/06 - Design features of general application for driving the stage of lowest order producing continuous revolution of the stage, e.g. with gear train
A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable head comprising a pipette tip, the head being configured, in use, to be moved between a position in which the pipette tip is in sealed engagement with the fixed section of pipette component and a position in which pipette tip is positioned adjacent to another of said plural segments. With the present invention a disposable sample preparation cartridge and corresponding analytical reader can be provided in a very cost effective and simple manner.
A pot for centrifugal separation of a biological fluid into multiple components. The pot comprises a wall (111) around a central axis (112), a top end (121) and a bottom end (113). The pot also comprises a plurality of baffles(114) protruding from the wall (111) into an inner volume of the pot, and/or a protrusion from the bottom end into the inner volume and around the central axis. Also, a consumable cartridge comprising the pot, a cartridge body adapted to receive the pot, and a first holding means. The first holding means is for holding the pot at least partly within the cartridge body, and is adapted to allow the pot to rotate.
A unit verification method to be performed on a unit under test (UUT) comprises connecting a verification device to the UUT. The verification device applies a set of challenge signals to the UUT and then measures the responses of the UUT to the challenge signals. The responses of the UUT are based on the challenge signals and the physical properties of the UUT. A registration key is generated based on the measured responses and is stored. The registration key is unique to the UUT.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry applies an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
G06F 21/75 - Protecting specific internal or peripheral components, in which the protection of a component leads to protection of the entire computer to assure secure computing or processing of information by inhibiting the analysis of circuitry or operation, e.g. to counteract reverse engineering
1, and at least one antenna feed element with an aperture or cross section having an order of symmetry C4 and supporting RF signals of two orthogonal polarizations is provided. At least one first substrate contains a plurality of antenna elements integrated into the substrate, with each antenna element capable of operating at two orthogonal polarizations. A plurality of phase shifters are connected to corresponding antenna elements, each phase shifter operating at two orthogonal polarizations, the output port of each phase shifter being connected to a short circuit.
H04L 12/28 - Data switching networks characterised by path configuration, e.g. LAN [Local Area Networks] or WAN [Wide Area Networks]
H01Q 1/52 - Means for reducing coupling between antennas Means for reducing coupling between an antenna and another structure
H01Q 3/42 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the relative phase or relative amplitude of energisation between two or more active radiating elementsArrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the distribution of energy across a radiating aperture varying the phase by electrical means using frequency-mixing
H01Q 5/50 - Feeding or matching arrangements for broad-band or multi-band operation
H04B 1/00 - Details of transmission systems, not covered by a single one of groups Details of transmission systems not characterised by the medium used for transmission
An acoustic droplet ejection apparatus comprises an acoustic actuator and a fluid well having abase and at least one side wall. The actuator is arranged to couple acoustic energy into the fluid well through the side wall.
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
There is provided a method of detecting the presence of a nucleic acid target sequence in which two oligonucleotides are used to form a three-way junction with the target sequence to allow detection of the target sequence. Alternatively, three oligonucleotides can be used to form a four-way junction with the target sequence to allow detection of the target sequence.
There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises: a fluid flow channel for receiving, in use, the flow of fluid; a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid; a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors and a plurality of temperature compensation particles are arranged throughout the media, where the temperature compensation particles have a temperature coefficient selected such that they compensate for temperature-related effects in the PUF device by making the permittivity and/or permeability of the media substantially temperature independent. Circuitry applies an electrical challenge signal to at least one or the conductors and receives an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
G09C 1/00 - Apparatus or methods whereby a given sequence of signs, e.g. an intelligible text, is transformed into an unintelligible sequence of signs by transposing the signs or groups of signs or by replacing them by others according to a predetermined system
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H01L 27/02 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier
A physically unclonable function (PUF) device comprises a plurality of optical fibres, at least some of which are arranged such that they are optically coupled. A media surround at least a portion of the optical fibres and at least one light source is configured to transmit light through one or more of the optical fibres. There is provided at least one light sensor configured to receive the transmitted light from one or more of the optical fibres and provide an output. Circuitry applies a challenge signal to at least one of the fibres using at least one light source and receives the output from the at least one light sensor, using the output to generate an identifying response to the challenge signal. The fibres are arranged such that the identifying response is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
G09C 1/00 - Apparatus or methods whereby a given sequence of signs, e.g. an intelligible text, is transformed into an unintelligible sequence of signs by transposing the signs or groups of signs or by replacing them by others according to a predetermined system
68.
ENVIRONMENTALLY DEPENDENT PHYSICALLY UNCLONABLE FUNCTION DEVICE
A physically unclonable function (PUF) comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least of portion of each of the conductors and further defines at least one cavity, where the cavity is structured to provide the device with an environmentally dependent characteristic. Circuitry applies an electrical challenge signal to at least one of the conductors and receives an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
G09C 1/00 - Apparatus or methods whereby a given sequence of signs, e.g. an intelligible text, is transformed into an unintelligible sequence of signs by transposing the signs or groups of signs or by replacing them by others according to a predetermined system
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A consumable cartridge for a particle sorter system, the consumable cartridge comprising: an inlet for receiving a particle-containing fluid; a microfluidic chip comprising: an input channel in fluidic connection with the inlet; and a particle sorter junction in fluidic connection with the input channel and comprising an output positive channel and an output negative channel; and first and second outlets in fluidic connection with the output positive channel and the output negative channel respectively, for discharging the fluid from the consumable cartridge, such that at least one enclosed fluidic path is provided in the consumable cartridge between the inlet and the first and second outlets.
The present invention relates to an analytical device and reaction chamber therefor. Specifically it relates to a device comprising a chamber with lobes configured such that altering the lobe configuration aids in the analytical interrogation of a portion of the fluid within the chamber.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
B01F 13/00 - Other mixers; Mixing plant, including combinations of dissimilar mixers
G01N 33/90 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving iron binding capacity of blood
71.
A METHOD OF PREPARING A SAMPLE FOR A DIAGNOSTIC ASSAY
The present invention relates to a method of preparing a sample for subsequent use in a diagnostic or analytical assay by concentrating the target analyte and/or removing interfering factors from the sample matrix. The present invention also relates to a fluidic device comprising a capture and release system connected to an immunodetection system.
A medicament delivery device for dispensing discrete doses of medicament comprises: first and second medicament carriers each comprising said doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer; first and second opening mechanisms each arranged to handle a respective one of the first and second medicament carriers and to open each compartment of the respective medicament carrier by separating the sealing layer from the carrier strip as the medicament carrier is advanced through the device; a take-up spool arranged to wind the separated sealing layers thereon such as to maintain the separated sealing layers in tension, each separated sealing layer having a path of travel between a respective one of the first and second opening mechanisms and the take-up spool; and a tension control element in contact with each of the separated sealing layers, wherein at least a part of the tension control element is arranged to be movable by a biasing force, which is exerted on the tension control element by the separated sealing layers as a result of any inequality in the tensions of the separated sealing layers wound by the take-up spool, to alter the length of the path of travel of each separated sealing layer so as to substantially equalise the tensions in the separated sealing layers.
A phased array antenna comprises an array of reflective cells, each cell being defined by a wall positioned within the array the wall arranged to define a waveguide, and having a moveable reflector positioned within the wall. Each reflector is arranged such that it is not in electrical contact with its respective wall and such that, in use it can be moved to tune the antenna. A feed and subreflector are positioned within the array and arranged to transmit and/or receive electromagnetic signals to and/or from the array.
H01Q 3/20 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system using mechanical relative movement between primary active elements and secondary devices of antennas or antenna systems for varying relative position of primary active element and a reflecting device wherein the primary active element is fixed and the reflecting device is movable
H01Q 19/19 - Combinations of primary active antenna elements and units with secondary devices, e.g. with quasi-optical devices, for giving the antenna a desired directional characteristic using reflecting surfaces having two or more spaced reflecting surfaces comprising one main concave reflecting surface associated with an auxiliary reflecting surface
H01Q 21/06 - Arrays of individually energised antenna units similarly polarised and spaced apart
H01Q 21/24 - Combinations of antenna units polarised in different directions for transmitting or receiving circularly and elliptically polarised waves or waves linearly polarised in any direction
H01Q 15/16 - Reflecting surfacesEquivalent structures curved in two dimensions, e.g. paraboloidal
A liquid droplet production apparatus (1) comprising a perforate membrane (50) and an actuator (30) is provided. The actuator(30) is configured to vibrate the perforate membrane (50) such that a liquid in contact with the perforate membrane (50) during use is caused to pass through at least one aperture of the perforate membrane and to be ejected as liquid droplets from the perforate membrane (50). The perforate membrane (50) includes one or more stiffening structures (60) for increasing the stiffness of the perforate membrane (50), the one or more stiffening structures (60) each being defined by a local transverse deformation (60) of the perforate membrane (50). A removable cartridge, a perforate membrane, and an actuator assembly for use in such a liquid droplet delivery apparatus are also provided, along with a method of manufacturing a perforate membrane for such a liquid droplet apparatus.
An acoustic sensor, comprising: a side wall, closed by first and second end walls to form a substantially cylindrical cavity for containing a fluid, wherein a radius, a, of the cavity and an axial height, h, of the cavity satisfies the inequality a/h is greater than 1.2; a transmitter, operatively associated with one of the first and second end walls; a receiver, operatively associated with the other of the first and second end walls; and a first stiffener plate, comprising an outer peripheral edge and an aperture which defines an inner peripheral edge, and located on an outer face of the first end wall such that the aperture overlies the axis of the cavity; wherein: the first end wall comprises at least one through-hole, located radially of the axis of the cavity between the inner and outer peripheral edges of the first stiffener plate; the first stiffener plate comprises at least one duct, which connects the at least one through-hole, of the first end wall, to at least one of the inner and outer peripheral edges of the first stiffener plate, thereby to provide at least one fluid passageway between the cavity and the external surroundings of the acoustic sensor via the first end wall; and in use: the transmitter causes oscillatory motion, of the one of the first and second end walls with which the transmitter is associated, in a direction substantially perpendicular to the plane of that end wall, such that axial oscillations of that end wall drive substantially radial oscillations of a fluid pressure in the cavity; and the substantially radial oscillations in the pressure of the fluid drive oscillatory motion of the other of the first and second end walls, with which the receiver is associated, generating an electrical signal.
G01N 29/22 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object Details
G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
G01N 29/28 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object Details providing acoustic coupling
An aerosol delivery system (1) is provided having a perforate membrane (150, 950) comprising a plurality of apertures, as well as a fluid reservoir (110) in fluid communication with a first side of the perforate membrane and actuation means (30) configured to vibrate the perforate membrane to cause a liquid in the fluid reservoir during use to be ejected as liquid droplets from a second side of the perforate membrane. The plurality of apertures comprises first and second arrays (951, 952) of apertures of first and second configurations which are grouped together in first and second discrete regions of the perforate membrane. The fluid reservoir includes first and second reservoir portions and a liquid barrier by which the first and second reservoir portions are separated. Also provided is a removable cartridge (100) for such an aerosol delivery system.
A micro-nozzle with an integrated filter structure for receiving fluids at pressures between 0.1 MPa to 50 MPa, comprising: at least one fluid inlet, a fluid outlet comprising at least one orifice, a primary filter structure positioned downstream from the at least one fluid inlet and arranged to provide statistical filtration of fluid passing therethrough.
B05B 15/40 - Filters located upstream of the spraying outlets
B01D 45/08 - Separating dispersed particles from gases or vapours by gravity, inertia, or centrifugal forces by utilising inertia by impingement against baffle separators
A cartridge (200) for an aerosol delivery system (1) is provided. The cartridge (200) includes a fluid reservoir (220) including a first reservoir portion (221) for containing a first liquid, a second reservoir portion (222) for containing a second liquid, and at least one liquid barrier (230) configured to separate the first and second reservoir portions, wherein the first and second reservoir portions have respective first and second openings at a first end of the cartridge. The cartridge further includes a perforate membrane (250) located at the first end of the cartridge and over the first and second openings. The first and second openings are configured to supply first and second liquids to a first side of the perforate membrane during use and the perforate membrane comprises a plurality of apertures configured to eject one or both of the first and second liquids from a second side of the perforate membrane in the form of liquid droplets when the perforate membrane is vibrated during use. Also provided is an aerosol delivery system (1) including such a cartridge.
A device for releasing discrete doses of medicament carried in a plurality of spaced-apart compartments on a medicament carrier, each compartment being arranged in a carrier strip and sealed by a sealing layer, the device comprising: a release mechanism arranged to engage between the carrier strip and the sealing layer so as to unseal at least a portion of the compartment and expose the medicament dose contained therein, wherein the release mechanism preferably covers said exposed compartment in place of the sealing layer.
A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of said opened compartment.
A sensing system for determining the location and orientation of an object which comprises a magnetic tag. The sensing system comprises selection coils and interrogation coils. The selection coils are arranged to generate a spatially-varying DC magnetic field from which the location of the tag can be determined in use. At least some of the interrogation coils are arranged to generate one or more AC magnetic fields and at least some of the interrogation coils are arranged to receive harmonics, intermodulation products or time dependent variations of the AC magnetic fields, from which the orientation of the tag is determined in use.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
G01V 3/10 - Electric or magnetic prospecting or detectingMeasuring magnetic field characteristics of the earth, e.g. declination or deviation operating with magnetic or electric fields produced or modified by objects or geological structures or by detecting devices using induction coils
G01V 15/00 - Tags attached to, or associated with, an object, in order to enable detection of the object
A droplet dispenser comprises a chamber (3) with a fluid inlet valve (2) and a fluid outlet valve (4). The chamber (3) is arranged such that the volume of the chamber may be varied in use to cause fluid to be alternately drawn in to the chamber (3) through the inlet valve (2) then subsequently expelled from the chamber through the outlet valve (4) to dispense a droplet. The droplet dispenser is capable of dispensing from an open reservoir and one may change the dispensed drop volume simply and easily. The droplet dispenser can also handle liquids which are normally seen as difficult to dispense, such as cyanoacrylate adhesives.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
B05C 5/02 - Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work from an outlet device in contact, or almost in contact, with the work
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
A counting mechanism (100) for a dispenser comprising: a first and a second housing part (110, 120) that are rotatable relative to each other; and a counting ring (130) disposed between the housing parts. The first housing part has a protrusion (111) which abuts the counting ring, holding a portion of the counting ring in contact with the second housing part. The relative rotation of the housing parts causes the protrusion to slide against the surface of the counting ring to drive a rolling movement of the counting ring around the circumference of the second housing part, such that a predefined rotation of the housing parts produces an incremental rotational displacement between the counting ring and second housing part to record a count. The counting mechanism provides a large gear reduction ratio in a compact form which is straightforward to manufacture and provides an accurate and reliable record of counts.
G06M 3/02 - Counters with additional facilities for performing an operation at a predetermined value of the count, e.g. arresting a machine
G06M 1/06 - Design features of general application for driving the stage of lowest order producing continuous revolution of the stage, e.g. with gear train
11, and at least one antenna feed element with an aperture or cross section having an order of symmetry C4 and supporting RF signals of two orthogonal polarizations is provided. At least one first substrate contains a plurality of antenna elements integrated into the substrate, with each antenna element capable of operating at two orthogonal polarizations. A plurality of phase shifters are connected to corresponding antenna elements, each phase shifter operating at two orthogonal polarizations, the output port of each phase shifter being connected to a short circuit.
H01Q 3/36 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the relative phase or relative amplitude of energisation between two or more active radiating elementsArrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the distribution of energy across a radiating aperture varying the phase by electrical means with variable phase-shifters
A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable head comprising a pipette tip, the head being configured, in use, to be moved between a position in which the pipette tip is in sealed engagement with the fixed section of pipette component and a position in which pipette tip is positioned adjacent to another of said plural segments. With the present invention a disposable sample preparation cartridge and corresponding analytical reader can be provided in a very cost effective and simple manner whilst still ensuring high quality sample preparation for analysis.
An acoustic droplet ejection apparatus comprises an acoustic actuator and a fluid well having a base and at least one side wall. The actuator is arranged to couple acoustic energy into the fluid well through the side wall.
B41J 2/045 - Ink jet characterised by the jet generation process generating single droplets or particles on demand by pressure, e.g. electromechanical transducers
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
A cap and seal system for a liquid medicament container. The system comprises a cap formed from a substantially rigid material, and has a retention component integrally formed therewith. A seal is formed from a material which is less hard than the cap and positioned within the cap such that, when the retaining component retains the cap on a container in use the seal is positioned such that it forms a fluid tight seal between the cap and the container. A recess is formed in the seal through which a liquid outlet channel can pass in use to access the contents of the container via the cap and the seal.
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry applys an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A physically unclonable function (PUF) device comprises a plurality of conductors, at least some of which are arranged so that they interact electrically and/or magnetically with one another. A media surrounds at least a portion of each of the conductors, and circuitry applys an electrical challenge signal to at least one of the conductors and for receiving an electrical output from at least one of the other conductors to generate an identifying response to the challenge signal that is unique to the device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
A device is provided for ejecting liquid as droplets or jets. The device comprises a chamber for holding liquid to be ejected. A plurality of fingers is disposed at a surface of the chamber. Each finger comprises at least one hole passing the finger. A plurality of actuators are provided, each being associated with a respective finger of the plurality of fingers and adapted to generate oscillatory motion of the finger, thereby causing liquid to be ejected from the chamber through the hole in the finger when in use. A plurality of rigid baffles is provided, each being arranged between neighbouring fingers of the plurality of fingers such that regions of the chamber in the vicinity of each finger are at least partially separated from each other. The chamber is at least partially bounded by a floor surface disposed opposite the plurality of fingers. Each of the rigid baffles is mechanically coupled to at least one of fingers. Each rigid baffle is directly attached to the floor surface.
There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises:a fluid flow channel for receiving,in use, the flow of fluid;a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid;a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
Medical apparatus and instruments; medical diagnostic
apparatus and instruments; diagnostic apparatus designed for
use in relation to assay and sensor developers; medical
diagnostic equipment; tools for medical diagnostics;
ultrasonic diagnostic apparatus.
Medical apparatus and instruments, namely, medical diagnostic apparatus for the detection of immunological diseases; medical diagnostic apparatus and instruments, namely, medical diagnostic apparatus for the detection of immunological diseases and medical devices for use in diagnosing immunological diseases, medical diagnostic instruments for the analysis of body fluids and body tissue; diagnostic apparatus designed for use in relation to assay and sensor developers, namely, medical biofeedback sensors; medical diagnostic apparatus and devices for the detection of immunological diseases; tools for medical diagnostics, namely, in vitro diagnostic machines for the detection of immunological diseases; ultrasonic diagnostics apparatus, for medical purposes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Non-medical diagnostic apparatus designed for use in
relation to assay and sensor developers. Medical apparatus and instruments; medical diagnostic
apparatus and instruments; medical diagnostic equipment;
tools for medical diagnostics; ultrasonic diagnostic
apparatus.
An apparatus for inductive temperature sensing comprises a coil configuration, a target, and an impedance measurement circuit. The target has a non-zero conductivity and susceptibility and the impedance measurement circuit measures the apparent inductance of the coil configuration at a measurement frequency close to the crossover frequency to provide an indication of temperature of the target.
G01K 7/38 - Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat using magnetic elements, e.g. magnets, coils the variations of temperature influencing the magnetic permeability
An acoustic sensor, comprising: a side wall, closed by first and second end walls to form a substantially cylindrical cavity for containing a fluid, wherein a radius, a, of the cavity and an axial height, h, of the cavity satisfies the inequality a/h is greater than 1.2; a transmitter, operatively associated with one of the first and second end walls; a receiver, operatively associated with the other of the first and second end walls; and a first stiffener plate, comprising an outer peripheral edge and an aperture which defines an inner peripheral edge, and located on an outer face of the first end wall such that the aperture overlies the axis of the cavity; wherein: the first end wall comprises at least one through-hole, located radially of the axis of the cavity between the inner and outer peripheral edges of the first stiffener plate; the first stiffener plate comprises at least one duct, which connects the at least one through-hole, of the first end wall, to at least one of the inner and outer peripheral edges of the first stiffener plate, thereby to provide at least one fluid passageway between the cavity and the external surroundings of the acoustic sensor via the first end wall; and in use: the transmitter causes oscillatory motion, of the one of the first and second end walls with which the transmitter is associated, in a direction substantially perpendicular to the plane of that end wall, such that axial oscillations of that end wall drive substantially radial oscillations of a fluid pressure in the cavity; and the substantially radial oscillations in the pressure of the fluid drive oscillatory motion of the other of the first and second end walls, with which the receiver is associated, generating an electrical signal.
G01N 29/024 - Analysing fluids by measuring propagation velocity or propagation time of acoustic waves
G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
G01N 29/22 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object Details
97.
APPARATUS AND METHOD FOR SORTING MICROFLUIDIC PARTICLES
A single-junction sorter for a microfluidic particle sorter, the single-junction sorter comprising: an input channel, configured to receive a fluid containing particles; an output sort channel and an output waste channel, each connected to the input channel for receiving the fluid therefrom; a bubble generator, operable to selectively displace the fluid around a particle to be sorted and thereby to create a transient flow of the fluid in the input channel; and a vortex element, configured to cause a vortex in the transient flow in order to direct the particle to be sorted into the output sort channel.
A nozzle plate (201) for use in a liquid droplet production apparatus and such apparatus, the nozzle plate comprising a flexible substrate having a linear array of nozzles that extend through said plate, said nozzles being arranged in at least one line, forming thereby a nozzle-bearing region, wherein the substrate is curved so as to impart an increased longitudinal stiffness to it. The apparatus comprises a piezo actuator (202, 203), which may have slots (211) separating fingers acting on the nozzle plate (201). The nozzle plate may be separable form the actuator.
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
B05B 7/06 - Spray pistolsApparatus for discharge with one outlet orifice surrounding another approximately in the same plane
B05B 17/00 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
B06B 1/06 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
G10K 11/36 - Devices for manipulating acoustic surface waves
99.
PRESSURE CONTROL SYSTEM, DEVICE AND METHOD FOR OPENING AN AIRWAY
The present invention provides a device with a pressure control system and methods for controlling the application of negative pressure to an external surface of an individual for creating and/or maintaining patency of the upper airway passage. The device is configured to fit under the chin of a subject at an external location corresponding approximately with the subject's internal soft tissue associated with the neck's anterior triangle. The pressure control system contains control module elements that may include circuit board elements, digital output barometer elements, sensor elements, processing elements and memory elements to optimize device function and safety of the device through regulation of the flow rate of the air pump.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Non-medical diagnostic apparatus designed for use in relation to assay and sensor developers, namely, laboratory probes for testing inorganic and organic solids, liquids and gases and any combination of inorganic and organic solids, liquids and gases for the purposes of sampling and monitoring; laboratory equipment in the nature of microscope slides, cartridges, namely, cartridges used for molecular and immunoassay specimen analysis for laboratory use; Non-medical diagnostic apparatus designed for use in relation to assay and sensor developers, namely, digital input and output scanners; Non-medical diagnostic apparatus designed for use in relation to assay and sensor developers, namely, programmable assay machines composed of a disposable robotic pipette system and light detectors for conduction of molecular and immunoassay tests Medical apparatus and instruments, namely, medical diagnostic apparatus for the detection of immunological diseases, medical diagnostic apparatus for medical diagnostic testing for use in relation to clinical testing, biological assay diagnostics and assay research; medical diagnostic apparatus and instruments, namely, multi-channel optics detection systems comprised of light detectors for detecting and identifying chemical and biological substances and thermal cycler modules; medical diagnostic equipment, namely, probes for medical testing of materials, namely, inorganic and organic solids, liquids and gases and any combination of inorganic and organic solids, liquids and gases for the purposes of sampling and monitoring; slides for use as medical collection devices for blood, urine, saliva, and body tissue; containers, namely, medical sample tubes and vials for holding or storing samples of fluids for the purpose of analysis of the containers' materials; X-ray scanners; ultrasonic medical diagnostic apparatus
