Abstract

A bacteriostatic composition, a preparation method therefor and a use thereof are provided. The bacteriostatic composition includes one or more of a fatty acid and/or a salt thereof, one or more of a dicarboxylic acid and/or a salt thereof, one or more of an aromatic alcohol, and one or more of an aromatic acid and/or a salt thereof. The bacteriostatic composition may be made into an aqueous solution, a water-soluble gel, a foam, a spray, an ointment, a powder, a film, a capsule, a suppository, or a tablet, and may be used for inhibiting harmful microorganisms, particularly abnormal flora within the vagina.

IPC Classes  ?

• A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 9/02 - SuppositoriesBougiesBases for suppositories or bougies
• A61K 9/20 - Pills, lozenges or tablets
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/194 - Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
• A61P 31/02 - Local antiseptics

Abstract

A bacteriostatic composition, a preparation method therefor and a use thereof. The bacteriostatic composition comprises one or more of a fatty acid and/or a salt thereof, one or more of a dibasic acid and/or a salt thereof, one or more of an aromatic alcohol, and one or more of an aromatic acid and/or a salt thereof. The bacteriostatic composition may be made into an aqueous solution, a water-soluble gel, a foam, a spray, an ointment, a powder, a film, a capsule, a suppository, or a tablet, and may be used for inhibiting harmful microorganisms, particularly abnormal flora within the vagina.

IPC Classes  ?

• A61K 8/34 - Alcohols
• A61K 8/36 - Carboxylic acidsSalts or anhydrides thereof
• A61K 8/362 - Polycarboxylic acids
• A61K 8/368 - Carboxylic acidsSalts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
• A61K 31/05 - Phenols
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/194 - Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
• A61L 15/44 - Medicaments
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina
• A61P 31/04 - Antibacterial agents

Abstract

A bacteriostatic composition, a preparation method therefor and a use thereof. The bacteriostatic composition comprises one or more of a fatty acid and/or a salt thereof, one or more of a dibasic acid and/or a salt thereof, one or more of an aromatic alcohol, and one or more of an aromatic acid and/or a salt thereof. The bacteriostatic composition may be made into an aqueous solution, a water-soluble gel, a foam, a spray, an ointment, a powder, a film, a capsule, a suppository, or a tablet, and may be used for inhibiting harmful microorganisms, particularly abnormal flora within the vagina.

IPC Classes  ?

• A61K 8/36 - Carboxylic acidsSalts or anhydrides thereof
• A61K 8/362 - Polycarboxylic acids
• A61K 8/368 - Carboxylic acidsSalts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
• A61K 8/34 - Alcohols
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 31/04 - Antibacterial agents

Abstract

A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).

IPC Classes  ?

• A61K 31/7016 - Disaccharides, e.g. lactose, lactulose
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - OintmentsBases therefor
• A61K 31/565 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
• A61K 36/886 - Aloeaceae (Aloe family), e.g. aloe vera
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina

Abstract

ABSTRACTThe present disclosure relates to a use of an antimicrobial agent combination in preparing a composition for vagina. The combination of antimicrobial agents is strong in inhibiting against Escherichia coli, and/or Staphylococcus aureus, and/or Candida. The present disclosure also relates to a composition for vagina, which has a strong inhibition effect on Escherichia coli, and/or Staphylococcus aureus, and/or Candida. Being used in the vagina, the composition can promote the restoration of beneficial lactobacillus, increase the acidity of the vagina. It is suitable for modulating microecology and balancing microorganism in the vagina, and selectively decontaminating vagina.CA 3039556 2019-05-27

IPC Classes  ?

• A61K 9/06 - OintmentsBases therefor
• A61K 9/08 - Solutions
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
• A61K 31/70 - CarbohydratesSugarsDerivatives thereof
• A61K 31/702 - Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina

Abstract

Uses of a bacteriostatic agent formula in preparing a composition for vaginal use. The bacteriostatic agent formula provides enhanced inhibitory effects with respect to Escherichia coli and/or Staphylococcus aureus and/or Candida. Also related is the composition for vaginal use that provides enhanced inhibitory effects with respect to Escherichia coli and/or Staphylococcus aureus and/or Candida, promotes restoration of beneficial Lactobacillus and enhances vaginal acidity when used in the vagina, and is applicable in the regulation of vaginal micro-ecology, regulation of vaginal flora, and selective vaginal decontamination.

IPC Classes  ?

• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 31/401 - ProlineDerivatives thereof, e.g. captopril
• A61K 31/70 - CarbohydratesSugarsDerivatives thereof
• A61K 31/702 - Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
• A61K 9/06 - OintmentsBases therefor
• A61K 9/08 - Solutions

Abstract

Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.

IPC Classes  ?

• A61K 31/7016 - Disaccharides, e.g. lactose, lactulose
• A61K 31/565 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - OintmentsBases therefor
• A61K 36/886 - Aloeaceae (Aloe family), e.g. aloe vera

Abstract

A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.

IPC Classes  ?

• A61K 31/7016 - Disaccharides, e.g. lactose, lactulose
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina

Abstract

A use of isomaltulose in the preparation of a composition for a vagina, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.

IPC Classes  ?

• A61K 31/7016 - Disaccharides, e.g. lactose, lactulose
• A61P 15/02 - Drugs for genital or sexual disordersContraceptives for disorders of the vagina