Goods & Services

Medical testing devices, namely, trays and skin test applicators for identifying reactions to allergens through application and exposure through the skin to diagnose allergies.

Abstract

Tree pollen allergy is a seasonal allergy caused by various airborne tree pollens. The allergy affects a significant percentage of the population, particularly in Europe and North America, and is characterized by symptoms such as sneezing, nasal congestion, runny nose, itchy and watery eyes, and throat irritation. The symptoms typically occur during the spring months when birch-, alder-, hazel- and oak trees release their pollen into the air. Tree pollen allergy is a type 1 hypersensitivity reaction mediated by immunoglobulin E (IgE) antibodies. The present invention relates to antibodies and antigen-binding fragments thereof that bind to one or more of tree pollen allergens; Bet v 1, Aln g 1, Cor a 1 and Que a 1, leading to inhibition of IgE mediated allergic reaction.

IPC Classes  ?

• A61P 37/08 - Antiallergic agents
• C07K 16/16 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from plants

Abstract

An autoinjector (1) is disclosed. The autoinjector comprises a main casing (10); a cartridge assembly (30) disposed within the main casing (10). The cartridge assembly may include a cartridge (3) land a needle (40). A power pack (100) is disposed within the main casing (10) for moving the cartridge (31) and the needle (40) from a storage position to an injection position when actuated. An actuation unit (50) comprises a cartridge container (52) and a needle cover (60) disposed between the cartridge container (52) and the main casing (10). The actuation unit (50) is operably coupled to the power pack (110) and retractable from a first position to an actuation position for actuating the power pack. The needle cover (60) is extendable to an extended position covering the needle (40) when the cartridge (31) and the needle (40) are in the injection position. A safety cap (20) is removable from a mounted position on a front end of the main casing (10) to expose a front portion of the actuation unit (50).

IPC Classes  ?

• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
• A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
• A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically

Abstract

Oral thin film comprising one or more layer(s), wherein at least one layer contains adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer, characterized in that the adrenaline is substantially undissolved in the at least one polymer. Method for preparing said oral thin film, comprising the steps: a) Preparing a solution comprising said at least one polymer and a solvent in which adrenaline or the pharmaceutically acceptable salt thereof is substantially insoluble, (b) addition of adrenaline, (c) spreading and drying the suspension obtained in step (b), in order to obtain a single-layer oral thin film, and Said oral thin film for use as a medicament, for use as a medicament in the treatment of allergic reactions.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
• A61P 37/08 - Antiallergic agents
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/38 - CelluloseDerivatives thereof
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Abstract

Oral thin film comprising adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer, characterized in that the water activity of the oral thin film is less than 0.6. Method for preparing said oral thin film, comprising the steps of a) preparing a solution, dispersion or melt comprising adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer and b) spreading the solution, dispersion or melt from step a) or the optionally foamed solution, dispersion or melt from step al) in order to obtain an oral thin film, and (c) drying the oral thin film obtained in step (b) in order to obtain an oral thin film having a water activity of less than 0.6. Said oral thin film for use as a medicament, particularly for use as a medicament in the treatment of allergic reactions.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 37/08 - Antiallergic agents
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/38 - CelluloseDerivatives thereof
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
• A61K 31/417 - Imidazole-alkylamines, e.g. histamine, phentolamine

Abstract

Disclosed are single domain antibody-based constructs, which are useful for treating IgE- related disorders or conditions by facilitating the dissociation of IgE from the high-affinity IgE receptor. Further disclosed are compositions comprising the constructs. Also nucleic acids and vectors are provides, as is methods of treatment of IgE related disorders

IPC Classes  ?

• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 16/42 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against immunoglobulins (anti-idiotypic antibodies)

Abstract

The present invention relates to a method for treating suddenly occurring allergic reactions, such as acute allergic reactions, in a human through administration of a BTK inhibitor. In particular, the present invention relates to a method for emergency treatment of a severe allergic reaction by administration of a BTK inhibitor to said human.

IPC Classes  ?

• A61K 31/4985 - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
• A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 37/08 - Antiallergic agents

Abstract

Disclosed is compositions and pharmaceutically acceptable formulations comprising the four peanut allergens Ara h 1, Ara h 2, Ara h 3, and Ara h 6, as well as a kit comprising the compositions or pharmaceutically acceptable formulations, and methods of their preparation and their use in mitigation of peanut allergy and their uses in peanut allergen-specific immunotherapy.

IPC Classes  ?

• A61K 39/35 - Allergens
• C07K 1/18 - Ion-exchange chromatography
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Goods & Services

Pharmaceutical and veterinary preparations for immunotherapeutic purposes; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; eye drops; nose drops, nasal sprays; pharmaceutical preparations for inhalers; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; dietary and nutritional supplements for humans and for animals; food supplements for humans and for animals; food supplements in the form of peanut powder for the prevention of allergies in humans or animals; probiotic supplements for humans and animals; probiotic preparations for medical and veterinary use; fish oil for medical and veterinary purposes, cod liver oil; dermatological preparations, dermatological pharmaceutical and veterinary preparations; medicated skin care preparations for humans and animals; skin care preparations for atopic skin in humans and animals; skin care preparations for the care of dry skin in humans and animals; dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; medicated bath and shower preparations for humans and animals; medicated hair care preparations for humans and animals; medicated sun-tanning preparations; infant formula, including lactose free infant formula and hydrolyzed milk formula; additives for infant formula to prevent the development of allergies; food for babies; diagnostic testing materials for medical use; allergy and asthma testing kits; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Scientific, checking (supervision), life-saving and teaching apparatus and instruments; computer software, particularly computer software for medical use; diagnostic apparatus for testing food, including for mould detection; sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products; downloadable electronic publications in the nature of magazines and periodicals; electronic magazines and periodicals; online questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Testing apparatus for medical purposes; spirometers [medical apparatus], including incentive spirometers for medical use; apparatus for carrying-out diagnostic tests for medical purposes; medical devices for self or home testing for allergy; electric devices for analysing the condition of allergy and asthma patients; inhalers for medical or therapeutic use; nebulizers for medical use; nasal filters; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management. Printed matter; instructional and teaching materials; magazines and periodicals; printed questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Compilation and collection into a computer database of scientific or pharmaceutical data relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to non-medicated cosmetics and toiletry preparations for humans and animals, non-medicated dentifrices for humans and animals, perfumery, essential oils for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to bleaching preparations and other substances for laundry use, cleaning, polishing, scouring and abrasive preparations, skin care preparations (not for medical use) for humans and animals, soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to deodorants for personal use, also for animals, hair care preparations for humans and animals, bath and shower preparations for humans and animals, sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical and veterinary preparations for immunotherapeutic purposes, pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, eye drops, nose drops, nasal sprays; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical preparations for inhalers, pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; wholesale and retail services, also online and via an e-commerce platform, in relation to dietary and nutritional supplements for humans and for animals, food supplements for humans and for animals, food supplements in the form of peanut powder for the prevention of allergies in humans or animals, probiotic supplements for humans and animals, probiotic preparations for medical and veterinary use, fish oil for medical and veterinary purposes, cod liver oil; wholesale and retail services, also online and via an e-commerce platform, in relation to dermatological preparations, dermatological pharmaceutical and veterinary preparations, medicated skin care preparations for humans and animals, skin care preparations for atopic skin in humans and animals, skin care preparations for the care of dry skin in humans and animals, dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to medicated bath and shower preparations for humans and animals, medicated hair care preparations for humans and animals, medicated sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to infant formula, including lactose free infant formula and hydrolyzed milk formula, additives for infant formula to prevent the development of allergies, food for babies, diagnostic testing materials for medical use, allergy and asthma testing kits; wholesale and retail services, also online and via an e-commerce platform, in relation to vacuum cleaners, vacuum cleaners for bedding, scientific, checking (supervision), life-saving and teaching apparatus and instruments, computer software, particularly computer software for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic apparatus for testing food, including for mould detection, sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products, downloadable electronic publications in the nature of magazines and periodicals, electronic magazines and periodicals, online questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to medical apparatus and instruments, testing apparatus for medical purposes, spirometers [medical apparatus], including incentive spirometers for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to apparatus for carrying-out diagnostic tests for medical purposes, medical devices for self or home testing for allergy, electric devices for analysing the condition of allergy and asthma patients, inhalers for medical or therapeutic use, nebulizers for medical use, nasal filters; wholesale and retail services, also online and via an e-commerce platform, in relation to air purifiers, including electric air purifiers, air filters for air purification, printed matter, instructional and teaching materials, magazines and periodicals, printed questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to bed linen, edible oils derived from fish; all these goods relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Providing access, with or without subscription, to an e-commerce platform on the Internet giving users access to medical information in the allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic disease as well as atopic dermatitis and food allergy fields; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials; computer services, namely the creation of online communities for registered users to participate in discussions, and engage in social networking; providing a website in relation to technology that enables consumers to form virtual communities, engage in social networking and share information regarding food, food components, and food products; statistical investigations and statistical studies in the fields of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, including through a website with or without subscription; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, including through a website; medical diagnostic services; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only.

Goods & Services

Testing apparatus for medical purposes, namely, immunochemical testing apparatus for medical use in relation to allergy and asthma; spirometers, namely, incentive spirometers for medical use; apparatus for carrying-out diagnostic tests for medical purposes, namely, medical diagnostic apparatus for testing for allergy and asthma; medical devices for self or home testing for allergy, namely, medical diagnostic apparatus for testing for allergies; electric devices for analyzing the condition of allergy and asthma patients, namely, medical diagnostic apparatus for detecting allergies and asthma; inhalers for medical or therapeutic use in relation to allergy and asthma; nebulizers for medical use in relation to allergy and asthma; nasal filters for medical purposes for allergy and asthma patients; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management Compilation and collection into a computer database of scientific and pharmaceutical data relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail store services, also online and via an e-commerce platform, featuring pharmaceutical and veterinary preparations for immunotherapeutic purposes, pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail store services, also online and via an e-commerce platform, featuring diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, eye drops, nose drops, nasal sprays; wholesale and retail store services, also online and via an e-commerce platform, featuring pharmaceutical preparations for inhalers, pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; wholesale and retail store services, also online and via an e-commerce platform, featuring dietary and nutritional supplements for humans and for animals, food supplements for humans and for animals, food supplements in the form of peanut powder for the prevention of allergies in humans or animals, probiotic supplements for humans and animals, probiotic preparations for medical and veterinary use, also online and via an e-commerce platform, in relation to infant formula, namely, lactose free infant formula and hydrolyzed milk formula, additives for infant formula to prevent the development of allergies, food for babies, diagnostic testing materials for medical use, allergy and asthma testing kits, scientific, checking and supervision, life-saving and teaching apparatus and instruments, computer software, particularly computer software for medical use; wholesale and retail store services, also online and via an e-commerce platform, featuring diagnostic apparatus for testing food, namely, for mould detection, sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products, downloadable electronic publications in the nature of magazines and periodicals, electronic magazines and periodicals, online questionnaires; wholesale and retail store services, also online and via an e-commerce platform, featuring medical apparatus and instruments, testing apparatus for medical purposes, spirometers, namely, incentive spirometers for medical use; wholesale and retail store services, also online and via an e-commerce platform, featuring apparatus for carrying-out diagnostic tests for medical purposes, medical devices for self or home testing for allergy, electric devices for analysing the condition of allergy and asthma patients, inhalers for medical or therapeutic use, nebulizers for medical use, nasal filters; wholesale and retail store services, also online and via an e-commerce platform, featuring printed matter, instructional and teaching materials, magazines and periodicals, printed questionnaires; wholesale and retail store services, also online and via an e-commerce platform, featuring bed linen, edible oils derived from fish; all the aforesaid goods relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only

Goods & Services

(1) Pharmaceutical and veterinary preparations for immunotherapeutic purposes; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; eye drops; nose drops, nasal sprays; pharmaceutical preparations for inhalers for the treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; food supplements in the form of peanut powder for the prevention of allergies in humans or animals; probiotic supplements for humans and animals; fish oil for medical and veterinary purposes, cod liver oil; pharmaceutical preparations for the treatment of dermatological diseases and disorders being dermatitis, eczema and psoriasis in humans and animals; medicated skin care preparations for humans and animals for the treatment of irritated, itching and inflamed skin; skin care preparations for atopic skin in humans and animals; skin care preparations for the care of dry skin in humans and animals; dermatitic preparations for treatment of dermatological conditions being eczema and psoriasis in humans and animals; medicated bath and shower preparations for humans and animals for the treatment of irritated, itching and inflamed skin; medicated topical hair care preparations for humans and animals for the treatment of allergic reactions, and dermatological conditions affecting the scalp, namely, dermatitis, eczema and psoriasis; medicated sun-tanning preparations; infant formula, in particular lactose free infant formula and hydrolyzed milk formula; additives for infant formula to prevent the development of allergies; food for babies; diagnostic testing materials for medical use, namely, diagnostic test patch for application to the skin for determining allergies; allergy and asthma testing kits; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma. (2) Computer software, namely downloadable computer software for medical use for assisting allergy and asthma patients and medical personnel in storing and handling patient medical data; diagnostic apparatus for testing food, namely, for mould detection; sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products; downloadable electronic publications in the nature of magazines and periodicals; electronic magazines and periodicals; online questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma. (3) Testing apparatus for medical purposes, namely, immunochemical tests for medical use in testing for allergy and asthma; spirometers [medical apparatus], namely, incentive spirometers for medical use; apparatus for carrying-out diagnostic tests for medical purposes, namely, medical diagnostic apparatus for testing for allergy and asthma; medical devices for self or home testing for allergy; electric devices for analyzing the condition of allergy and asthma patients, namely, medical diagnostic apparatus for detecting allergies and asthma; inhalers for medical or therapeutic use; nebulizers for medical use; nasal filters; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management (4) Printed matter, namely, printed calendars and partially printed forms; printed instructional and teaching materials in the field of allergy and asthma; magazines and periodicals; printed questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma. (1) Compilation and collection into a computer database of scientific or pharmaceutical data relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to non-medicated cosmetics and toiletry preparations for humans and animals, non-medicated dentifrices for humans and animals, perfumery, essential oils for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to bleaching preparations and other substances for laundry use, cleaning, polishing, scouring and abrasive preparations, skin care preparations (not for medical use) for humans and animals, soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to deodorants for personal use, also for animals, hair care preparations for humans and animals, bath and shower preparations for humans and animals, sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical and veterinary preparations for immunotherapeutic purposes, pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, eye drops, nose drops, nasal sprays; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical preparations for inhalers, pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; wholesale and retail services, also online and via an e-commerce platform, in relation to dietary and nutritional supplements for humans and for animals, food supplements for humans and for animals, food supplements in the form of peanut powder for the prevention of allergies in humans or animals, probiotic supplements for humans and animals, probiotic preparations for medical and veterinary use, fish oil for medical and veterinary purposes, cod liver oil; wholesale and retail services, also online and via an e-commerce platform, in relation to dermatological preparations, dermatological pharmaceutical and veterinary preparations, medicated skin care preparations for humans and animals, skin care preparations for atopic skin in humans and animals, skin care preparations for the care of dry skin in humans and animals, dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to medicated bath and shower preparations for humans and animals, medicated hair care preparations for humans and animals, medicated sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to infant formula, in particular lactose free infant formula and hydrolyzed milk formula, additives for infant formula to prevent the development of allergies, food for babies, diagnostic testing materials for medical use, allergy and asthma testing kits; wholesale and retail services, also online and via an e-commerce platform, in relation to vacuum cleaners, vacuum cleaners for bedding, computer software, particularly computer software for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic apparatus for testing food, namely, for mould detection, sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products, downloadable electronic publications in the nature of magazines and periodicals, electronic magazines and periodicals, online questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to medical apparatus and instruments, testing apparatus for medical purposes, spirometers [medical apparatus], namely, incentive spirometers for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to apparatus for carrying-out diagnostic tests for medical purposes, medical devices for self or home testing for allergy, electric devices for analysing the condition of allergy and asthma patients, inhalers for medical or therapeutic use, nebulizers for medical use, nasal filters; wholesale and retail services, also online and via an e-commerce platform, in relation to air purifiers, namely, electric air purifiers, air filters for air purification, printed matter, instructional and teaching materials, magazines and periodicals, printed questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to bed linen, edible oils derived from fish; all these goods relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only. (2) Providing access, with or without subscription, to an e-commerce platform on the Internet giving users access to medical information in the allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic disease as well as atopic dermatitis and food allergy fields; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only. (3) Scientific, technological, medical, and pharmacological research services and design relating thereto, namely, scientific research and technological research in the field of pharmaceutical manufacturing processes, medical research, pharmaceutical research, pharmaceutical products development and new product design; scientific research laboratories for conducting research in the field of allergies and asthma, medical laboratory services, clinical trials; computer services, namely the creation of online communities for registered users to participate in discussions, and engage in social networking; providing a website in relation to technology that enables consumers to form virtual communities, engage in social networking and share information regarding food, food components, and food products; statistical investigations and statistical studies in the fields of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only. (4) Medical services and medical healthcare services in the field of allergies and asthma; medical consulting services, namely, counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, and through a website with or without subscription; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, and through a website; medical diagnostic services; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only.

Goods & Services

Providing access, with or without subscription, to an e-commerce platform on the Internet giving users access to medical information in the allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic disease as well as atopic dermatitis and food allergy fields, namely, providing access to telecommunication networks; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only Pharmaceutical and veterinary preparations for immunotherapeutic purposes for the treatment of autoimmune diseases; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing strips for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; eye drops; nose drops, nasal sprays for medical purposes; pharmaceutical preparations for inhalers for the treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; ; probiotic preparations for medical and veterinary use; infant formula, namely, lactose free infant formula and hydrolyzed milk infant formula; additives for infant formula to prevent the development of allergies, namely, dietary supplements; food for babies; diagnostic testing materials for medical use, namely, diagnostic test patch for application to the skin for determining allergies; allergy and asthma testing kits, namely, diagnostic test patch for application to the skin for determining allergic reactions; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma computer software, namely downloadable computer software for medical use for assisting allergy and asthma patients and medical personnel in storing and handling patient data; diagnostic apparatus for testing food, namely, for mold detection; optical sensors for detecting and analyzing the presence of chemicals, toxins, mold and allergens in food, food components and food products; downloadable electronic publications in the nature of magazines and periodicals in the field of allergy and asthma; downloadable electronic magazines and periodicals in the field of allergy and asthma; online downloadable electronic questionnaires on medical issues relating to allergy and asthma; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma Printed matter, namely, printed calendars and forms; printed instructional and teaching materials except apparatus in the field of allergy and asthma; printed magazines and periodicals in the field of allergy and asthma; printed questionnaires on medical issues relating to allergy and asthma; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and asthma Scientific, technological, medical, and pharmacological research services and design relating thereto, namely, scientific research and technological research in the field of manufacturing processes, medical research, pharmaceutical research, pharmaceutical products development and new product design; scientific and medical laboratory services; medical and scientific research, namely, conducting clinical trials for others; computer services, namely, the creation of online communities for registered users to participate in discussions, and engage in social networking; providing a website featuring technology that enables consumers to form virtual communities, engage in social networking and share information regarding food, food components, and food products; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; statistical investigations and statistical studies in the fields of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, namely, medical research; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only Medical services and medical healthcare services; medical consulting services, namely, counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, including through a website with or without subscription, namely, medical consultations; providing medical information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, including through a website; medical diagnostic services, namely, medical diagnostic testing, monitoring and reporting services; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and asthma only

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical research laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Goods & Services

Recorded and downloadable media, computer software; Downloadable electronic books, booklets, brochures, newsletters, reports, educational and course materials, publications, journals, video and sound recordings, podcasts and multimedia files; Downloadable computer software for education and training and for use in relation to exhibitions, symposiums and seminars; Downloadable mobile applications; Downloadable applications for mobile devices. Education and training, also online; Organisation of exhibitions, symposiums and seminars, also of online exhibitions, symposiums and seminars; Providing of training, also online; Providing on-line electronic publications, not downloadable; Publication of electronic books and journals on-line. Health and medical services and consultancy, also online, in relation to medical issues; Pharmacy advice, also online.

Abstract

The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

IPC Classes  ?

• A61K 39/35 - Allergens
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/20 - Pills, lozenges or tablets
• A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Goods & Services

Laboratory supplies, namely, vials for scientific purposes and vials for laboratory use Medical diagnostic instruments, namely, vials for medical diagnostic use, vials and other containers for blood and other medical and veterinary samples Glass vials, glass bottles, and glass vials and ampoules for medication, all sold empty

Goods & Services

(1) Vials for scientific purposes; vials for laboratory use (2) Vials for medical diagnostic use; vials and other containers for blood and other medical and veterinary samples (3) Glass vials and glass receptacles in the nature of glass bottles for medication sold empty; glass vials and ampoules for medication sold empty (1) Scientific and technological services, namely, scientific research investigations for medical purposes and scientific and medical research and development in the field of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; industrial analysis and research services in the nature of laboratory services, namely, laboratory research in the field of allergy and asthma; industrial analysis and research services, namely, diagnostic services in the field of allergy and asthma; medical and scientific research in the field of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases.

Goods & Services

Non-medicated cosmetics and toiletry preparations for humans and animals; non-medicated dentifrices for humans and animals; perfumery, essential oils for humans and animals; bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; skin care preparations (not for medical use) for humans and animals; soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; deodorants for personal use, also for animals; hair care preparations for humans and animals; bath and shower preparations for humans and animals; sun-tanning preparations; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management, but all solely being non- medicated and for use in relation to allergy and/or asthma. Pharmaceutical and veterinary preparations for immunotherapeutic purposes; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; eye drops; nose drops, nasal sprays; pharmaceutical preparations for inhalers; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; dietary and nutritional supplements for humans and for animals; food supplements for humans and for animals; food supplements in the form of peanut powder for the prevention of allergies in humans or animals; probiotic supplements for humans and animals; probiotic preparations for medical and veterinary use; fish oil for medical and veterinary purposes, cod liver oil; dermatological preparations, dermatological pharmaceutical and veterinary preparations; medicated skin care preparations for humans and animals; skin care preparations for atopic skin in humans and animals; skin care preparations for the care of dry skin in humans and animals; dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; medicated bath and shower preparations for humans and animals; medicated hair care preparations for humans and animals; medicated sun-tanning preparations; infant formula, including lactose free infant formula and hydrolyzed milk formula; additives for infant formula to prevent the development of allergies; food for babies; diagnostic testing materials for medical use; allergy and asthma testing kits; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Vacuum cleaners; vacuum cleaners for bedding. Scientific, checking (supervision), life-saving and teaching apparatus and instruments; computer software, particularly computer software for medical use; diagnostic apparatus for testing food, including for mould detection; sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products; downloadable electronic publications in the nature of magazines and periodicals; electronic magazines and periodicals; online questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Testing apparatus for medical purposes; spirometers [medical apparatus], including incentive spirometers for medical use; apparatus for carrying-out diagnostic tests for medical purposes; medical devices for self or home testing for allergy; electric devices for analysing the condition of allergy and asthma patients; inhalers for medical or therapeutic use; nebulizers for medical use; nasal filters; none of the aforesaid goods for use in the cardiovascular field nor for use in continence management. Air purifiers, including electric air purifiers; air filters for air purification; none of the aforesaid goods for use in continence management. Printed matter; instructional and teaching materials; magazines and periodicals; printed questionnaires; none of the aforesaid goods relating to the cardiovascular field nor for use in continence management, but all solely for use in relation to allergy and/or asthma. Bed linen; none of the aforesaid goods for use in continence management. Edible oils derived from fish [other than cod liver oil]. Statistical investigations and statistical studies in the fields of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; compilation and collection into a computer database of scientific or pharmaceutical data relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to non-medicated cosmetics and toiletry preparations for humans and animals, non-medicated dentifrices for humans and animals, perfumery, essential oils for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to bleaching preparations and other substances for laundry use, cleaning, polishing, scouring and abrasive preparations, skin care preparations (not for medical use) for humans and animals, soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to deodorants for personal use, also for animals, hair care preparations for humans and animals, bath and shower preparations for humans and animals, sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical and veterinary preparations for immunotherapeutic purposes, pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, eye drops, nose drops, nasal sprays; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical preparations for inhalers, pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; wholesale and retail services, also online and via an e-commerce platform, in relation to dietary and nutritional supplements for humans and for animals, food supplements for humans and for animals, food supplements in the form of peanut powder for the prevention of allergies in humans or animals, probiotic supplements for humans and animals, probiotic preparations for medical and veterinary use, fish oil for medical and veterinary purposes, cod liver oil; wholesale and retail services, also online and via an e-commerce platform, in relation to dermatological preparations, dermatological pharmaceutical and veterinary preparations, medicated skin care preparations for humans and animals, skin care preparations for atopic skin in humans and animals, skin care preparations for the care of dry skin in humans and animals, dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to medicated bath and shower preparations for humans and animals, medicated hair care preparations for humans and animals, medicated sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to infant formula, including lactose free infant formula and hydrolyzed milk formula, additives for infant formula to prevent the development of allergies, food for babies, diagnostic testing materials for medical use, allergy and asthma testing kits; wholesale and retail services, also online and via an e-commerce platform, in relation to vacuum cleaners, vacuum cleaners for bedding, scientific, checking (supervision), life-saving and teaching apparatus and instruments, computer software, particularly computer software for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic apparatus for testing food, including for mould detection, sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products, downloadable electronic publications in the nature of magazines and periodicals, electronic magazines and periodicals, online questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to medical apparatus and instruments, testing apparatus for medical purposes, spirometers [medical apparatus], including incentive spirometers for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to apparatus for carrying-out diagnostic tests for medical purposes, medical devices for self or home testing for allergy, electric devices for analysing the condition of allergy and asthma patients, inhalers for medical or therapeutic use, nebulizers for medical use, nasal filters; wholesale and retail services, also online and via an e-commerce platform, in relation to air purifiers, including electric air purifiers, air filters for air purification, printed matter, instructional and teaching materials, magazines and periodicals, printed questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to bed linen, edible oils derived from fish; all these goods relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Providing access, with or without subscription, to an e-commerce platform on the Internet giving users access to medical information in the allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic disease as well as atopic dermatitis and food allergy fields; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials; computer services, namely the creation of online communities for registered users to participate in discussions, and engage in social networking; providing a website in relation to technology that enables consumers to form vir-tual communities, engage in social networking and share information regarding food, food components, and food products; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, e.g. through a website with or without subscription; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, e.g. through a website; medical diagnostic services; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; none of the aforesaid services in relation to the cardiovascular field nor in relation to continence management, but all in relation to allergy and/or asthma only.

Goods & Services

Pharmaceutical and veterinary preparations for immunotherapeutic purposes; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, rhinoconjunctivitis, allergic asthma and respiratory allergic diseases, particularly sublingual preparations; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use.

Abstract

The invention provides methods related to the detection of specific biomarkers in combination with use of immunotherapy products for treatment of atopic disease. More specifically, biomarkers useful for selecting subjects for treating, preventing, or reducing risk of asthma by use of immunotherapy, e.g. allergen-specific immunotherapy. Further, the invention provides immunotherapy products for use in methods involving the detection of one or more biomarkers, as well as kits of parts for detection of biomarkers related to asthma.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Goods & Services

diagnostic test injection for application to the skin for determining allergies, said injection containing a compound called penicilloyl polylysine created by from bonding penicilloic acid to a polymer of lysine

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, rhinoconjunctivitis, allergic asthma and respiratory allergic diseases and pharmaceutical preparations for prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases

Goods & Services

Mobile apps featuring information on allergy and asthma related issues; application software featuring information on allergy and asthma related issues. Medical services in the field of allergy and asthma; providing medical information in the field of allergy and asthma via a website; providing medical information in the field of allergy and asthma via a mobile app.

Abstract

Disclosed herein are otic product kits for administration of a sterilized formulation. In some embodiments, the otic product kit comprises: an aseptic container containing the sterilized formulation; a syringe; and an administration needle connectable to the syringe, wherein the sterilized formulation comprising: from about 5.5 wt % to about 6.5 wt % multiparticulate ciprofloxacin; from about 15 wt % to about 17 wt % poloxamer 407; and water. Also disclosed herein are methods of preparing and administrating the sterilized formulation. In some embodiments, the method comprising (1) transferring the sterilized otic formulation from an aseptic container to a syringe through a preparation needle; (2) replacing the preparation needle with an administration needle; and (3) injecting the sterilized otic formulation from the syringe through the administration needle into the ear of a patient.

IPC Classes  ?

• A61P 27/16 - Otologicals
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61F 15/00 - Auxiliary appliances for wound dressingsDispensing containers for dressings or bandages
• A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
• A61M 5/178 - Syringes
• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
• A61M 31/00 - Devices for introducing or retaining media, e.g. remedies, in cavities of the body
• A61K 9/14 - Particulate form, e.g. powders
• A61B 46/20 - Surgical drapes specially adapted for patients
• A61F 7/10 - Cooling bags, e.g. ice-bags

Goods & Services

Computer software for use in medical decision support systems in the allergy immunotherapy field; computer software for use in digital interfaces directed at healthcare professionals in the allergy immunotherapy field; computer software for use by healthcare professionals enabling these to personalize medicine and doses of medicine for allergy patients, and to better motivate allergy patients to continue treatment; computer software for use by healthcare professionals enabling these to obtain an early objective measure of individual patient exposure to medication, namely in relation to exposure to allergy immunotherapy (sublingual tablets). Medical devices, apparatus and instruments for use by healthcare professionals, namely medical devices enabling healthcare professionals to personalize medicine and doses of medicine for allergy patients, and to better motivate allergy patients to continue treatment; medical devices, apparatus and instruments for use by healthcare professionals enabling these to obtain an early objective measure of individual patient exposure to medication, namely in relation to exposure to allergy immunotherapy (sublingual tablets).

Goods & Services

Pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions Apparatus and instruments containing pharmaceutical preparations, substances and medicines, particularly adrenaline, namely, medical fluid injectors and syringes for medical purposes and for injections; hypodermic injectors, namely, medical fluid injectors and hypodermic needles and holders for hypodermic injectors, namely, hypodermic syringes; structural parts for all the aforesaid goods

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Abstract

The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope mid a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.

IPC Classes  ?

• A61K 38/10 - Peptides having 12 to 20 amino acids
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• A61K 39/36 - Allergens from pollen
• A61P 27/14 - Decongestants or antiallergics
• A61P 11/02 - Nasal agents, e.g. decongestants
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

Abstract

An injector is provided for performing an injection operation comprising a housing (104), a needle extendable from a front end of the housing, a rear end of the housing and a longitudinal axis extending between the front end and the rear end, a safety pin (116) in an actuation locked position coupled to the housing and moveable to a safety released position coupled to the housing. The injector is locked against actuation when the safety pin is in the actuation locked position and the injector is ready for actuation of the injection operation when the safety pin is in the safety released position.

IPC Classes  ?

• A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, e.g. through s website; medical diagnostic services.

Abstract

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 8/04 - DispersionsEmulsions
• A61K 9/06 - OintmentsBases therefor
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
• A61K 9/14 - Particulate form, e.g. powders
• A61P 27/16 - Otologicals
• A61K 9/10 - DispersionsEmulsions
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin

Goods & Services

Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases, and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, namely, for the treatment, monitoring and diagnosing of allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, diagnostic reagents and diagnostic testing materials being medical diagnostic test strips, diagnostic test patch for application to the skin for determining allergies, medical diagnostic test media in the form of test strips, all for medical use in diagnosing, preventing and treating allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases Medical and pharmacological research services in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; conducting clinical trials for others Medical consulting services, namely, counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support, namely, providing medical and health care information, all relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums and electronically or digitally through the Internet; providing health and medical information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet

Abstract

Disclosed herein are methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/06 - OintmentsBases therefor
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases, and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, namely, for the treatment, monitoring and diagnosing of allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, diagnostic reagents and diagnostic testing materials for medical use in diagnosing, preventing and treating allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases. (1) Medical and pharmacological research services in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; clinical trials. (2) Medical consulting services, namely counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums and electronically or digitally through the Internet; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet.

Goods & Services

Non-medicated cosmetics and toiletry preparations for humans and animals; non-medicated dentifrices for humans and animals; perfumery, essential oils for humans and animals; bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; skin care preparations (not for medical use) for humans and animals; soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; deodorants for personal use, also for animals; hair care preparations for humans and animals; bath and shower preparations for humans and animals; sun-tanning preparations; none of the aforesaid goods for use in the cardiovascular field; but all solely for use in relation to allergy and/or asthma. Pharmaceutical and veterinary preparations for immunotherapeutic purposes; pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; eye drops; nose drops, nasal sprays; pharmaceutical preparations for inhalers; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; dietary and nutritional supplements for humans and for animals; food supplements for humans and for animals; food supplements in the form of peanut powder for the prevention of allergies in humans or animals; probiotic supplements for humans and animals; probiotic preparations for medical and veterinary use; fish oil for medical and veterinary purposes, cod liver oil; dermatological preparations, dermatological pharmaceutical and veterinary preparations; medicated skin care preparations for humans and animals; skin care preparations for atopic skin in humans and animals; skin care preparations for the care of dry skin in humans and animals; dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; medicated bath and shower preparations for humans and animals; medicated hair care preparations for humans and animals; medicated sun-tanning preparations; infant formula, including lactose free infant formula and hydrolyzed milk formula; additives for infant formula to prevent the development of allergies; food for babies; diagnostic testing materials for medical use; allergy and asthma testing kits; none of the aforesaid goods for use in the cardiovascular field; but all solely for use in relation to allergy and/or asthma. Vacuum cleaners; vacuum cleaners for bedding. Scientific, checking (supervision), life-saving and teaching apparatus and instruments; computer software, particularly computer software for medical use; diagnostic apparatus for testing food, including for mould detection; sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products; downloadable electronic publications in the nature of magazines and periodicals; electronic magazines and periodicals; online questionnaires; none of the aforesaid goods relating to the cardiovascular field; but all solely for use in relation to allergy and/or asthma. Medical apparatus and instruments; testing apparatus for medical purposes; spirometers [medical apparatus], including incentive spirometers for medical use; apparatus for carrying-out diagnostic tests for medical purposes; medical devices for self or home testing for allergy; electric devices for analysing the condition of allergy and asthma patients; inhalers for medical or therapeutic use; nebulizers for medical use; nasal filters; none of the aforesaid goods for use in the cardiovascular field; but all solely for use in relation to allergy and/or asthma. Air purifiers, including electric air purifiers; air filters for air purification. Printed matter; instructional and teaching materials; magazines and periodicals; printed questionnaires; none of the aforesaid goods relating to the cardiovascular field; but all solely for use in relation to allergy and/or asthma. Bed linen. Edible oils derived from fish [other than cod liver oil]. Investigations and statistical studies in the fields of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; compilation and collection into a computer database of scientific or pharmaceutical data relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to non-medicated cosmetics and toiletry preparations for humans and animals, non-medicated dentifrices for humans and animals; perfumery, essential oils for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to bleaching preparations and other substances for laundry use, cleaning, polishing, scouring and abrasive preparations, skin care preparations (not for medical use) for humans and animals, soaps, body and beauty care preparations for the care of the skin and of the face, for humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to deodorants for personal use, also for animals, hair care preparations for humans and animals, bath and shower preparations for humans and animals, sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical and veterinary preparations for immunotherapeutic purposes, pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use in the field of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy, eye drops, nose drops, nasal sprays; wholesale and retail services, also online and via an e-commerce platform, in relation to pharmaceutical preparations for inhalers, pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; wholesale and retail services, also online and via an e-commerce platform, in relation to dietary and nutritional supplements for humans and for animals, food supplements for humans and for animals, food supplements in the form of peanut powder for the prevention of allergies in humans or animals, probiotic supplements for humans and animals, probiotic preparations for medical and veterinary use, fish oil for medical and veterinary purposes, cod liver oil; wholesale and retail services, also online and via an e-commerce platform, in relation to dermatological preparations, dermatological pharmaceutical and veterinary preparations, medicated skin care preparations for humans and animals, skin care preparations for atopic skin in humans and animals, skin care preparations for the care of dry skin in humans and animals, dermatitic preparations for treatment of eczema, psoriasis and dermatological conditions in humans and animals; wholesale and retail services, also online and via an e-commerce platform, in relation to medicated bath and shower preparations for humans and animals, medicated hair care preparations for humans and animals, medicated sun-tanning preparations; wholesale and retail services, also online and via an e-commerce platform, in relation to infant formula, including lactose free infant formula and hydrolyzed milk formula, additives for infant formula to prevent the development of allergies, food for babies, diagnostic testing materials for medical use, allergy and asthma testing kits; wholesale and retail services, also online and via an e-commerce platform, in relation to vacuum cleaners, vacuum cleaners for bedding, scientific, checking (supervision), life-saving and teaching apparatus and instruments, computer software, particularly computer software for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to diagnostic apparatus for testing food, including for mould detection, sensors for detecting and analyzing the presence of chemicals, toxins, mould and allergens in food, food components and food products, downloadable electronic publications in the nature of magazines and periodicals, electronic magazines and periodicals, online questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to medical apparatus and instruments, testing apparatus for medical purposes, spirometers [medical apparatus], including incentive spirometers for medical use; wholesale and retail services, also online and via an e-commerce platform, in relation to apparatus for carrying-out diagnostic tests for medical purposes, medical devices for self or home testing for allergy, electric devices for analysing the condition of allergy and asthma patients, inhalers for medical or therapeutic use, nebulizers for medical use, nasal filters; wholesale and retail services, also online and via an e-commerce platform, in relation to air purifiers, including electric air purifiers, air filters for air purification, printed matter, instructional and teaching materials, magazines and periodicals, printed questionnaires; wholesale and retail services, also online and via an e-commerce platform, in relation to bed linen, edible oils derived from fish; all these goods relating to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field; but aall in relation to allergy and/or asthma only. Providing access, with or without subscription, to an e-commerce platform on the Internet giving users access to medical information in the allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic disease as well as atopic dermatitis and food allergy fields; none of the aforesaid services in relation to the cardiovascular field. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials; computer services, namely the creation of online communities for registered users to participate in discussions, and engage in social networking; providing a website featuring technology that enables consumers to form virtual communities, engage in social networking and share information regarding food, food components, and food products; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis and food allergy; none of the aforesaid services in relation to the cardiovascular field. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, eg through a website with or without subscription; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases, atopic dermatitis, food allergy, and anaphylactic reactions, also electronically or digitally, eg through a website; medical diagnostic services; all of the aforesaid services in relation to allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, respiratory allergic diseases as well as atopic dermatitis, food allergy, and anaphylactic reactions; none of the aforesaid services in relation to the cardiovascular field.

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Abstract

The invention relates to novel immunogenic polypeptides identified in house dust mites and storage mites, which have the potential to be used in allergy immunotherapy, for diagnostic purposes, eventually via production of antibodies binding the polypeptide or for characterising allergen extracts of house dust mites and storage mites.

IPC Classes  ?

• A61K 39/35 - Allergens
• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

Goods & Services

Chemicals used in research and science; diagnostic preparations for scientific or research purposes. Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases as well as rhinoconjunctivitis; diagnostic preparations for medical purposes, including diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergies, asthma, rhinitis and respiratory diseases as well as rhinoconjunctivitis; diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; prefilled injectors containing pharmaceutical preparations, substances and medicines, particularly adrenaline, for medical purposes. Surgical, medical, dental and veterinary devices as well as surgical, medical, dental and veterinary apparatus and instruments; diagnostic devices, apparatus and instruments for medical use, diagnostic test kits and devices for medical use; inhalers; medical devices and injectors for treatment of anaphylactic reactions; hypodermic injectors and holders for hypodermic injectors; parts and fittings (not included in other classes) for all the aforesaid goods. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; medical services, namely providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions, also electronically or digitally through a website; medical services, namely providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions, also electronically or digitally through a website; medical diagnostic services.

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases, and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, namely, for the treatment, monitoring and diagnosing of allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, diagnostic reagents and diagnostic testing materials for medical use in diagnosing, preventing and treating allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases. (1) Medical and pharmacological research services in relation to allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; clinical trials. (2) Medical consulting services, namely counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums and electronically or digitally through the Internet; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet.

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Abstract

The present invention relates to T cell epitope-containing polypeptides derived from pollen allergens Ambrosia Artemisiifolia (Amb a), Ambrosia psilostachya (Amb p), Ambrosia trifida (Amb t) and Artemisia vulgaris (Art v) and novel allergens found in pollen of Amb p, Amb t and Art v and which are considered homologous to the allergens Amb a 3, Amb a 4, Amb a 8 and Amb a 11. The invention further relates to the use of such polypeptides and novel allergens for modulating an immune response, for treating an allergic response and/or for inducing or promoting immunological tolerance, and for use in diagnostic methods and kits.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases; diagnostic preparations for medical purposes, namely, diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergy, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory allergic diseases; diagnostic reagents and diagnostic testing materials in diagnosing, preventing and treating allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis, and respiratory allergic diseases

Goods & Services

Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosing, prevention and treatment of allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory diseases; diagnostic preparations for medicinal purposes, namely, diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory diseases [ Scientific and technological services, namely, scientific investigations for medicinal purposes and scientific and medical research and development relating thereto; industrial analysis and research services in the nature of laboratory services, namely, laboratory research in the field of allergy and asthma, laboratory diagnostic services in the field of allergy and asthma, medical and scientific research ] [ Medical services, including, diagnostic services; consultancy on health, including consultancy and information services on allergies, asthma, allergic rhinitis, allergic asthma, rhinoconjunctivitis and respiratory diseases ]

Abstract

An injector is provided for performing an injection operation comprising a housing (104), a needle extendable from a front end of the housing, a rear end of the housing and a longitudinal axis extending between the front end and the rear end, a safety pin (116) in an actuation locked position coupled to the housing and moveable to a safety released position coupled to the housing. The injector is locked against actuation when the safety pin is in the actuation locked position and the injector is ready for actuation of the injection operation when the safety pin is in the safety released position.

IPC Classes  ?

• A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles

Abstract

The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope and a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention provides peptide combinations for use in immunotherapy for the treatment of allergy to cedar and cypress pollen, e.g. Japanese cedar pollen and related cross-reactive pollen from members of the cypress family (Cupressaceae). The peptide combinations, which are designed to have a high worldwide HLA coverage, comprise at least three different peptides, including at least one Cry j 1 peptide and at least one Cry j 2 peptide.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• A61P 37/08 - Antiallergic agents

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, rhinoconjunctivitis, allergic asthma and respiratory allergic diseases, and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases. (2) Diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for diagnosing, preventing and treating allergies, asthma, rhinitis, rhinoconjunctivitis and respiratory diseases. (3) Pharmaceutical preparations in the form of injectable pharmaceuticals, namely, injectable adrenaline for treatment of anaphylactic reactions and injectable preparations for treatment and prevention of allergies, asthma, rhinitis, rhinoconjunctivitis and respiratory diseases. (1) Medical and pharmacological research services; medical laboratory services, clinical trials. (2) Medical consulting services, namely, providing counselling and medical information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; providing patient support relating to immunotherapy and the diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet.

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes in relation to allergies, asthma, allergic rhinitis, rhinoconjunctivitis, allergic asthma and respiratory allergic diseases, and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases. (2) Diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for diagnosing, preventing and treating allergies, asthma, rhinitis, rhinoconjunctivitis and respiratory diseases. (3) Pharmaceutical preparations in the form of injectable pharmaceuticals, namely, injectable adrenaline for treatment of anaphylactic reactions and injectable preparations for treatment and prevention of allergies, asthma, rhinitis, rhinoconjunctivitis and respiratory diseases. (1) Medical and pharmacological research services; medical laboratory services, clinical trials. (2) Medical consulting services, namely, providing counselling and medical information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; providing patient support relating to immunotherapy and the diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet.

Abstract

Disclosed herein are methods of making sterilized ciprofloxacin compositions. In some embodiments, the method includes the steps of: (a) forming an aqueous suspension comprising ciprofloxacin particles; (b) heating the aqueous suspension comprising ciprofloxacin particles at a temperature range of from about 100° C. to about 120° C.; and (c) allowing the aqueous suspension comprising ciprofloxacin particles to cool down. Also described herein are otic formulations containing ciprofloxacin formed by the disclosed methods, and therapeutic use of such otic formulation for providing sustained release of ciprofloxacin into the ear for treating various otic disorders and conditions.

IPC Classes  ?

• A61K 9/14 - Particulate form, e.g. powders
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 31/47 - QuinolinesIsoquinolines
• A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 9/06 - OintmentsBases therefor

Abstract

The invention relates to combinations of peptides or variants thereof derived from a portion of an amino sequence of a house dust mite allergen, e.g. the allergens Der p 1, Der f 1, Der p 2 and/or Der f 2. Such peptides comprise at least one T cell epitope and a significant high number of patients in a worldwide population will have HLA alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by a dust mite.

IPC Classes  ?

• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 39/35 - Allergens

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical research laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Abstract

The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

IPC Classes  ?

• A61K 39/35 - Allergens
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/20 - Pills, lozenges or tablets
• A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 9/10 - DispersionsEmulsions
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/06 - OintmentsBases therefor
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
• A61K 8/04 - DispersionsEmulsions
• A61K 9/14 - Particulate form, e.g. powders

Abstract

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/10 - DispersionsEmulsions
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/06 - OintmentsBases therefor
• A61K 9/14 - Particulate form, e.g. powders
• A61K 8/04 - DispersionsEmulsions
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins

Abstract

A composition comprising at least one first allergen, which is a respiratory allergen belonging to a first biological source material group, for use in prophylactic treatment of allergy to at least one second allergen, which is selected from the group consisting of a respiratory and a venomous allergen belonging to a second biological source material group and a food allergen of a food composition, in a subject, wherein the subject has not developed any clinical symptoms of allergy to the first allergen and to the second allergen, and wherein the first and second biological source material groups are not the same.

IPC Classes  ?

• A61K 36/899 - Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
• A61P 37/08 - Antiallergic agents

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Goods & Services

Pharmaceutical preparations for the prevention and treatment of allergies

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical research laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, for example, through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, for example, through a website; medical diagnostic services.

Abstract

Disclosed herein are methods for the treatment of pediatric otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids

Abstract

The invention relates to polypeptides identified in pollen of several different plant families. The polypeptides comprises sequences of amino acid residues conserved across the different plant families, such as across grass, weed and tree pollen families. The invention further relates to the use of such polypeptides or their conserved amino acid residues as a molecule (e.g. an immunogenic molecule) in modifying an immune response against itself or another unrelated antigen (e.g. major allergen of a pollen source) possible via induction of bystander tolerance.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Goods & Services

Sustained release therapeutic formulations for the ear; pharmaceuticals for the treatment of disorders and diseases of the ear; controlled release therapeutic formulations for the ear; pharmaceuticals for the treatment of disorders and diseases of the ear; pharmaceuticals; antivirals; veterinary preparations; biological and chemical preparations for medical or veterinary use; clinical medical reagents; diagnostic kits and preparations for medical or veterinary use. Pharmaceutical research, development and clinical trial services; drug discovery; clinical research and consulting services, namely, managing and providing clinical trials for pharmaceutical drugs and other medical and diagnostic products; management, performance and evaluation of clinical trials; clinical testing services; pharmaceutical, clinical, laboratory and medical research; development services in the field of pharmaceuticals, drugs and other medical and diagnostic products; scientific, pharmaceutical, biochemical and genomics research and development services; provision of information to others on the subjects of scientific, pharmaceutical and medical research and development; consultancy services relating to pharmaceutical, medical and drug research; processing of data and preparation of reports from clinical trials; providing a website featuring pharmaceutical research, pharmaceutical development and clinical trial information. Providing medical information in the field of auditory diseases and indications; surgical, diagnostic and therapeutic services relating to the ear; medical aftercare services; information and advisory services relating to pharmaceuticals and the prevention and treatment of diseases and medical conditions, including such services provided on-line from a computer network or the Internet; medical evaluation services; medical monitoring services; medical diagnostic testing, monitoring and reporting services; consulting services in the fields of health and healthcare; medical information; medical screening; medical services; medical testing for diagnostic or treatment purposes; providing a web site featuring medical information; providing a website featuring health and healthcare information; internet-based health care information services; information, advisory and consultancy services relating to the aforesaid;   consultancy services in the field of pharmaceuticals, drugs and other medical products.

Goods & Services

(1) Sustained release pharmaceutical preparations, namely ciprofloxacin, for the prevention and treatment of disorders and diseases of the ear; pharmaceuticals, namely ciprofloxacin, for the treatment of disorders and diseases of the ear; Sustained release pharmaceutical preparations for the prevention and treatment of disorders and diseases of the ear, namely acute otitis media with tympanostomy tubes and acute otitis externa; pharmaceuticals for the treatment of disorders and diseases of the ear, namely acute otitis media with tympanostomy tubes and acute otitis externa, (1) Providing medical information in the field of auditory diseases and indications

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, e.g. through a website; diagnostic services (medical).

Goods & Services

Diagnostic preparations for scientific or research purposes. Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, including diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic reagents and diagnostic testing materials for medical use. Medical apparatus and instruments; diagnostic apparatus and instruments for medical use, diagnostic test kits (empty) and test devices for medical use; parts and fittings (not included in other classes) for all the aforesaid goods.

Abstract

The invention relates to combinations of peptides or variants thereof derived from a portion of an amino sequence of a house dust mite allergen, e.g. the allergens Der p 1, Der f 1, Der p 2 and/or Der f 2. Such peptides comprise at least one T cell epitope and a significant high number of patients in a worldwide population will have HLA alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by a dust mite.

IPC Classes  ?

• A61K 39/35 - Allergens
• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, eg through a website; medical diagnostic services.

Abstract

The invention relates to pan grass pollen immunogens such as polypeptides, proteins and peptides, and methods and uses of such immunogens for modulating or relieving an immune response in a subject. For example, the pan grass pollen immunogens can be used for treating a subject for an allergic immune response or inducing or promoting immunological tolerance to the immunogen or a non-grass pollen allergen in a subject.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

The invention relates to pan pollen immunogens such as polypeptides, proteins and peptides, and methods and uses of such immunogens for modulating or relieving an immune response in a subject. For example, the immunogens can be used for treating a subject for an allergic immune response or inducing or promoting immunological tolerance to the immunogen or a pollen allergen in a subject.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Goods & Services

(1) Pharmaceutical preparations for the treatment and prevention of allergies

Goods & Services

Pharmaceutical preparations for the treatment and prevention of allergies

Goods & Services

Sustained release therapeutic formulations for the ear; pharmaceuticals for the treatment of disorders and diseases of the ear Providing medical information in the field of auditory diseases and indications

Abstract

The present invention relates to novel methods for the identification of specific mite species in a sample, such as mass reared sample or an environmental sample. The invention further relates to nucleic acid molecules encoding the structural ribosomal RNA elements (r RNA) as well as to the non-functional RNA situated between such structural ribosomal RNAs of specific mite species and its use for designing primers for use in the method.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

Goods & Services

Diagnostic preparations for scientific purposes, namely, diagnostic preparations used in science related to the field of treatment, monitoring and diagnosing of diseases such as allergies, asthma, rhinitis and respiratory diseases Medical and veterinary apparatus and instruments, namely, injection syringes, [ automatic vaccination apparatus including vaccination by aerosol and transcutaneous jets; inhalers for medical purposes sold empty; ] medical instruments in the nature of syringes sold empty and [ medical fluid injectors sold empty for treatment of anaphylactic reactions; medical fluid injectors sold empty intended for pharmaceutical preparations, substances and medicines, particularly adrenaline; hypodermic injectors in the nature of hypodermic syringes and holders specially adapted for holding hypodermic injectors; ] medical and veterinary apparatus and instruments, namely, diagnostic apparatus and instruments in the nature of syringes, syringe holders [, evacuators, assays material; diagnostic test kits, comprised of syringes, syringe holders, evacuators, assays material, sold empty for medical use, ] and medical diagnostic test kits sold empty for diagnosing allergies

Goods & Services

Diagnostic preparations for scientific purposes. Pharmaceutical and veterinary preparations and substances for the diagnosis, prevention and treatment of allergy and asthma; pharmaceutical and veterinary preparations and substances for immunotherapeutic purposes; diagnostic and test preparations and substances for immunotherapeutic purposes. Scientific and technological services and research and design relating thereto; industrial analysis and research services; laboratory research services, medical and scientific research.

Abstract

c) quantifying the absolute amount of allergen by correlating the amount of the allergen calibration standard peptide(s) with the amount of the corresponding peptide(s) of the degraded allergen sample by mass analysis.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides
• A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
• C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof
• C07K 4/00 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof
• C07K 5/00 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof
• C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof
• C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving peptidase or proteinase
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases, also electronically or digitally, e.g. through a website; medical diagnostic services.

Goods & Services

(1) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, namely, for the treatment, monitoring and diagnosing of allergies, asthma, rhinitis and repiratory diseases, diagnostic reagents and diagnostic testing materials for medical use, namely, for diagnosing, preventing and treating allergies, asthma, rhinitis and repiratory diseases; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; inhalers; medical devices, namely, injectors for treatment of anaphylactic reactions; hypodermic injectors and holders for hypodermic injectors; parts and fittings for all the aforesaid goods. (2) Pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions; apparatus and instruments containing pharmaceutical preparations, substances and medicines, particularly adrenaline, namely, injectors for the treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; hypodermic injectors and holders for hypodermic injectors; parts and fittings for all the aforesaid goods.

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases. Medical and scientific research and design relating thereto; industrial analysis and research services, including laboratory testing services. Medical services and medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases; providing patient support relating to immunotherapy as well as to prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases also electronically or digitally, e.g. through a website; diagnostic services (medical).

Goods & Services

Chemicals used in research and science; diagnostic preparations for scientific or research purposes, including diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergies, asthma, rhinitis and respiratory diseases. Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents and diagnostic testing materials for medical use; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions. Surgical, medical, dental and veterinary devices, apparatus and instruments; diagnostic devices, apparatus and instruments for medical use, diagnostic test kits and devices for medical use; inhalers; medical devices and injectors for treatment of anaphylactic reactions; apparatus, devices, injectors and instruments containing pharmaceutical preparations, substances and medicines, particularly adrenaline; hypodermic injectors and holders for hypodermic injectors; parts and fittings (not included in other classes) for all the aforesaid goods. Scientific, technological, medical and pharmacological research services and design relating thereto; scientific and medical laboratory services, clinical trials. Medical services and medical healthcare services; medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions, also electronically or digitally, e.g. through a website; medical diagnostic services.

Goods & Services

Pharmaceutical and veterinary preparations, including pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases. Medical and scientific research and design relating thereto; industrial analysis and research services, including laboratory services. Medical services and medical consulting services, including counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases; providing patient support relating to immunotherapy as well as to prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases, also electronically or digitally, e.g. through a website; providing information to medical professionals relating to immunotherapy as well as diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases also electronically or digitally, e.g. through a website; diagnostic services.

Goods & Services

(1) Diagnostic preparations for scientific or research purposes, namely, diagnostic preparations for the treatment, monitoring and diagnosing of allergies, asthma, rhinitis and respiratory diseases. (2) Pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma and respiratory allergic diseases. (3) Diagnostic preparations for medical purposes, namely, diagnostic reagents and diagnostic testing materials for diagnosing, preventing and treating allergies, asthma, rhinitis and respiratory diseases. (4) Pharmaceutical preparations in the form of injectable pharmaceuticals, namely, injectable adrenaline for treatment of anaphylactic reactions and injectable preparations for treatment and prevention of allergies, asthma, rhinitis and respiratory diseases. (5) Diagnostic devices, apparatus and instruments for medical use, namely, diagnostic test kits for diagnosing, preventing and treating allergies, asthma, rhinitis and respiratory diseases; inhalers, namely inhalers for therapeutic use; medical devices, namely, injectors for treatment of anaphylactic reactions; hypodermic injectors and holders for hypodermic injectors; parts and fittings for all the aforesaid goods. (1) Medical and pharmacological research services and design relating to pharmaceutical and veterinary preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma as well as respiratory allergic diseases. (2) Medical laboratory services, clinical trials. (3) Medical consulting services, namely, providing counselling and medical information regarding immunotherapy, allergy, asthma, allergic rhinitis and allergic asthma, respiratory allergic diseases and anaphylactic reactions. (4) Providing patient support relating to immunotherapy and the diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis and allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet. (5) Providing information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions diseases through printed publications, pamphlets, brochures, flyers, through telephone, through meetings, conferences, symposiums, and electronically or digitally through the Internet.

Goods & Services

[ Chemicals used in research and science; diagnostic preparations for scientific or research purposes, namely, diagnostic preparations for the treatment, monitoring and diagnosing of diseases such as allergies, asthma, rhinitis and respiratory diseases ] Pharmaceutical [ and veterinary ] preparations, namely, pharmaceutical and veterinary preparations for immunotherapeutic purposes and pharmaceutical and veterinary preparations for diagnosis, prevention and treatment of allergy, asthma [, allergic rhinitis, allergic asthma ] and respiratory allergic diseases; diagnostic preparations for medical purposes, diagnostic reagents for medical use; diagnostic testing kits comprised of diagnostic assays, specimen holders, diagnostic preparation agents and specimen preparation agents for medical use [ ; pharmaceutical preparations in the form of injectable pharmaceuticals, particularly adrenaline, for treatment of anaphylactic reactions ] Medical services and medical healthcare services; medical consulting services, namely, counselling and information regarding immunotherapy, allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; providing patient support relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions, namely, medical consultations; providing medical information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; providing a website featuring medical information to medical professionals relating to immunotherapy as well as to diagnosing, prevention and treatment of allergy, asthma, allergic rhinitis, allergic asthma, respiratory allergic diseases and anaphylactic reactions; medical testing for diagnostic or treatment purposes

Abstract

The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

IPC Classes  ?

• A23J 1/00 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites
• A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
• A61K 35/64 - Insects, e.g. bees, wasps or fleas
• A61K 39/35 - Allergens
• A61K 39/36 - Allergens from pollen
• C07K 1/00 - General processes for the preparation of peptides
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/20 - Pills, lozenges or tablets
• A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites

Abstract

The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.

IPC Classes  ?

• A61K 39/35 - Allergens
• A61K 39/36 - Allergens from pollen
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

IPC Classes  ?

• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 8/04 - DispersionsEmulsions
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/10 - DispersionsEmulsions
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/06 - OintmentsBases therefor
• A61K 9/14 - Particulate form, e.g. powders
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins

Goods & Services

Pharmaceutical preparations for the treatment and prevention of allergies

Goods & Services

Pharmaceutical preparations for the treatment and prevention of allergies

Goods & Services

Medical testing kits to detect and diagnose a penicillin allergy.

Goods & Services

(1) Pharmaceutical preparations for the prevention and treatment of allergies.

Goods & Services

Pharmaceutical preparations for the prevention and treatment of allergies

Abstract

A stabilized composition comprising at least one adrenergic compound and at least one antioxidant selected from the group consisting of a bisulfite, a metabisulfite and a sulfite compound.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
• A61K 47/02 - Inorganic compounds
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61K 33/04 - Sulfur, selenium or telluriumCompounds thereof

Abstract

The present invention relates to antigens and methods for the suppression of a hypersensitivity immune response via bystander suppression with an antigen unrelated to the allergen triggering a hypersensitivity immune response such as an allergic response in an individual. Treatment regiments covering the administering the unrelated antigen to the oral cavity (e.g. sublingual mucosa) combined with the administration of the unrelated antigen to either the respiratory tract, gastro-intestinal tract or skin in a simultaneous, contemporaneous, separate or sequential manner is provided.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 38/38 - Albumins
• A61P 37/00 - Drugs for immunological or allergic disorders

Abstract

The present invention relates to the treatment of a hypersensitivity immune response, such as allergic rhinitis or asthma, via bystander suppression by use of an antigen unrelated to the allergen triggering the hypersensitivity immune response in an individual to be treated, wherein the antigen is obtainable from the source material comprising the "triggering" allergen.

IPC Classes  ?

• A61K 39/36 - Allergens from pollen
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 38/38 - Albumins
• A61P 37/00 - Drugs for immunological or allergic disorders

Abstract

The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

IPC Classes  ?

• A23J 1/00 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites
• A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
• A61K 35/64 - Insects, e.g. bees, wasps or fleas
• A61K 39/35 - Allergens
• A61K 39/36 - Allergens from pollen
• C07K 1/00 - General processes for the preparation of peptides
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 17/00 - Carrier-bound or immobilised peptidesPreparation thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/20 - Pills, lozenges or tablets
• A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites

Goods & Services

Pharmaceutical preparations, including preparations for immunotherapeutic purposes and preparations for diagnosis, prevention and treatment of allergies, allergic rhinitis and asthma, including allergic asthma. Medical services and medical consulting services, including counselling and information regarding immunotherapy, allergy, allergic asthma, allergic rhinitis and asthma; providing patient support relating to immunotherapy as well as to prevention and treatment of allergy, allergic asthma, allergic rhinitis and asthma through a website; providing information to medical professionals relating to immunotherapy as well as prevention and treatment of allergy, allergic asthma, allergic rhinitis and asthma through a website.

Abstract

The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

IPC Classes  ?

• A61K 35/64 - Insects, e.g. bees, wasps or fleas
• A61K 39/35 - Allergens
• A61P 37/08 - Antiallergic agents

Abstract

The present invention relates to mucosal allergen-specific immunotherapy with a seasonal allergen, wherein the therapy is initiated after start of the pollen season of the seasonal allergen. Preferably, the seasonal allergen is provided in solid dosage form and is administered daily. Furthermore, advantageously, the same dose may be used throughout the treatment period since up-dosing is not required.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 39/35 - Allergens
• A61K 39/36 - Allergens from pollen
• A61K 39/38 - Antigens from snakes
• A61K 9/00 - Medicinal preparations characterised by special physical form

Goods & Services

Paper, cardboard and goods made from these materials, not included in other classes; printed matter; book binding material; photographs; stationery; adhesives for stationery or household purposes; artists' materials; paint brushes; typewriters and office requisites (except furniture); instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); printers' type; printing blocks; written materials, booklets, brochures. Education and training, organisation of exhibitions, symposiums and seminars; providing of training; entertainment; sporting and cultural activities; Providing on-line electronic publications, not downloadable; Publication of electronic books and journals on-line. Health and medical services and consultancy in relation to medical issues; veterinary services; hygienic and beauty care for human beings or animals; agriculture, horticulture and forestry services; Pharmacy advice.

Goods & Services

Diagnostic preparations for scientific purposes. Pharmaceutical and veterinary preparations and substances for the diagnosis, prevention and treatment of allergy and asthma; pharmaceutical and veterinary preparations and substances for immunotherapeutic purposes; diagnostic and test preparations and substances for immunotherapeutic purposes. Scientific and technological services and research and design relating thereto; industrial analysis and research services; laboratory services, medical and scientific research.

Abstract

This invention relates to the use of a pharmaceutical product comprising allergen and optionally an adjuvant for fast up-dosing in connection with allergy vaccination wherein a reduced number of injections are used. The invention also relates to the pharmaceutical product as such.

IPC Classes  ?

• A61K 39/35 - Allergens
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 37/08 - Antiallergic agents