The present invention provides an analysis device for diagnosing an ischemic stroke, the device comprising: a sample insertion part into which a specimen is inserted; a reagent part including an antibody which forms a biomarker-antibody complex by specifically reacting with an ischemic stroke biomarker in the specimen inserted via the sample insertion part; and a detection part for capturing and detecting the biomarker-antibody complex, the ischemic stroke biomarker comprising a glial fibrillary acidic protein (GFAP) and an N-terminal pro-B-type natriuretic peptide (Nt-pro-BNP).
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
2.
LATERAL FLOW ASSAY DEVICE FOR TRAUMATIC BRAIN INJURY DIAGNOSIS USING TIME-RESOLVED FLUORESCENCE ANALYSIS, AND METHOD FOR DIAGNOSING TRAUMATIC BRAIN INJURY BY USING SAME
A lateral flow assay device for detecting a traumatic brain injury marker according to an embodiment of the present invention comprises: a sample pad into which a blood sample containing a traumatic brain injury marker is injected; an adsorption pad comprising a probe which is mixed with the marker when the traumatic brain injury marker migrates from the sample pad, to form a traumatic brain injury marker complex; and a porous membrane which is in fluid communication with the adsorption pad and allows capillary movement of the traumatic brain injury marker complex from the adsorption pad to a detection line, wherein the probe comprises: capture antibodies consisting of antibodies labeled with a specific binding material that specifically binds to the traumatic brain injury marker; and detector antibodies consisting of antibodies labeled with a fluorescent material with a relatively long emission lifetime of 1 microsecond or greater, and, as the antibodies labeled with a specific binding material or a fluorescent material, a mixture of antibodies derived from at least two different species is used.
The present invention relates to a sample solution heating apparatus for ex vivo diagnosis, and provided is a sample solution heating apparatus for ex vivo diagnosis, the apparatus: injecting a heating body into a reaction container in which a sample solution is stored and induction-heating the heating body by means of a primary induction coil, so as to directly transfer, through the heating body in the sample solution, heat to the sample solution without additional heat transfer media, thereby minimizing heat loss, and thus can rapidly heat the sample solution so as to enable more rapid diagnosis, and can improve energy efficiency; and induction-heating the heating body inside the reaction container and, simultaneously, rotating same by using magnetic force, so as to perform a stirring function, in addition to a simple heating function, on the sample solution, thereby enabling more rapid and accurate ex vivo diagnosis.
The present invention relates to an immunoassay test strip using a capacitive sensor, and provides an immunoassay test strip using a capacitive sensor, wherein immunoassay diagnosis is performed by detecting capacitance changes that occur as target substances are captured in a reaction region, and it is thus unnecessary to use a separate light source device to detect the substances captured in the reaction region. Accordingly, the overall size of an immunoassay diagnostic device can be miniaturized, the structure thereof can be simplified, and the detection accuracy can be further improved by preventing detection errors caused by the external environment during light detection.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
G01N 33/558 - ImmunoassayBiospecific binding assayMaterials therefor using diffusion or migration of antigen or antibody
5.
METHOD FOR MANUFACTURING TEST STRIP FOR MULTIPLEX IMMUNOASSAY ANALYSIS, AND TEST STRIP MANUFACTURED USING SAME
The present invention relates to a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same. The present invention relates to a test strip for multiplex immunoassay analysis and a multiplex immunoassay analysis device using same, and provides a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same, which include a first reactant linked to a fluorescent substance and a second reactant linked to a reflective light substance that are applied as reactants for detecting a target analyte in a biosample, thereby enabling both fluorescence detection and reflected light detection of the target analyte in one reaction region so as to improve diagnosis accuracy, and that can be selectively applied to a fluorescent-type immunoanalytical diagnostic device or a reflective-type immunoanalytical diagnostic device according to the needs of a user so as to increase ease of use, and can detect two target analytes through fluorescent light and reflective light in one reaction region so as to enable multiplex analysis by means of a simple and miniaturized structure having one reaction region.
The present invention relates to a diagnostic apparatus for an immunoassay, and provides a diagnostic apparatus for an immunoassay, whereby, without separately moving a sample strip or an optical module, a mask, having a slit part formed, is simply disposed, and the position of the slit part is altered, and thus a testing light may be accurately irradiated on a reaction region of the sample strip, and fluorescence or a reflected light, occurring from the reaction region of the sample strip, may be accurately detected, and thus diagnostic accuracy and convenience of use may be improved therethrough.
The present invention relates to a test strip for multiplex immunoassay analysis and a multiplex immunoassay analysis device using same, wherein, as reactants for exploring a target analyte in a biosample, a first reactant linked to a fluorescent substance and a second reactant linked to a reflective light substance are applied, thereby enabling both fluorescence analysis and reflective analysis of the target analyte in one reaction region and improving diagnosis accuracy. In addition, the reactants can selectively be applied to a fluorescent-type immunoanalytical diagnostic device or a reflective-type immunoanalytical diagnostic device according to the needs of a user, thereby increasing ease of use, and in one reaction region, two target analytes may be inspected through fluorescent light or reflective light, thus providing a multiplex immunoassay test strip and immunoassay analysis device using same with a simple and miniaturized structure having one reaction region.
The present invention relates to an immunoassay device. An immunoassay device according to an embodiment of the present invention may comprise an assay case which has a predetermined space formed therein, has, in one side surface thereof, a strip insertion hole through which a test strip is inserted, the test strip being capable of performing a test for a reactant for detecting a target analyte of a biological sample, and has, in the top surface thereof, an assay hole through which a mobile terminal is securely mounted, the mobile terminal being for performing an immunoassay on detection light generated from the test strip, by using an image acquired by imaging the detection light generated by test light irradiated to the test strip. According to the present invention, by inserting the test strip into the assay case, irradiating the inserted test strip with the test light, and imaging light reflected by the irradiated test light to perform an assay, there is an effect whereby diagnosis results obtained through the test strip can be conveniently analyzed.
The present invention provides a method for operating a diagnostic device, the method comprising the steps of: putting a sample including a reactant into a reaction well; pouring a buffer solution into the reaction well; reacting the reactant with conjugates in the reaction well to form a reaction product; removing the buffer solution from the reaction well; and measuring the reaction product.
The present invention comprises: pressing a buffer container above a crushing part; crushing a first separation membrane of the buffer container by means of the crushing part; and supplying a buffer solution into the crushing part through an inlet opening of the crushing part. Supplying the buffer solution through the inlet opening comprises lifting the first separation membrane to a protrusion part which protrudes from a main wall of the crushing part so as to separate the top surface of the main wall and the first separation membrane from each other.
Provided in the present invention is a reference cassette for a fluorescence immunoassay diagnostic device, the cassette having, arranged in a case, fluorescent glass capable of maintaining fluorescence characteristics to be constant without causing degeneration, so as to accurately provide reference measurement information about the fluorescence detection amount during testing of the measurement accuracy of the fluorescence detection of the immunoassay diagnostic device, so that testing accuracy can improve, preventing decrease in measurement accuracy and being semi-permanently usable since the denaturation or deterioration of the fluorescent glass does not occur even if the cassette is used continuously, and providing a mask having a slit so as to limit the area of the fluorescent glass to be externally exposed to a specific area, thereby generating the type of fluorescence that is the same as that of a reaction area of a sample strip to be actually used, and thus more accurate reference measurement information can be provided.
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