The present invention provides an analysis device for diagnosing an ischemic stroke, the device comprising: a sample insertion part into which a specimen is inserted; a reagent part including an antibody which forms a biomarker-antibody complex by specifically reacting with an ischemic stroke biomarker in the specimen inserted via the sample insertion part; and a detection part for capturing and detecting the biomarker-antibody complex, the ischemic stroke biomarker comprising a glial fibrillary acidic protein (GFAP) and an N-terminal pro-B-type natriuretic peptide (Nt-pro-BNP).
medical diagnostic apparatus and instruments for testing blood; light absorption analysis apparatus for medical purposes;
cartridges for medical purposes, namely, cartridge for testing blood; medical equipment for testing blood; analytical apparatus for
automatic analysis of biological sample for medical purposes; diagnostic kits consisting of medical devices and apparatus,
namely, diagnostic kits for testing blood; cartridge for analyzing biological sample for medical purpose; equipment and apparatus
for testing biological sample for medical purpose
3.
METHOD FOR MANUFACTURING TEST STRIP FOR MULTIPLEX IMMUNOASSAY ANALYSIS, AND TEST STRIP MANUFACTURED USING SAME
The present disclosure relates to a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same. The present invention relates to a test strip for multiplex immunoassay analysis and a multiplex immunoassay analysis device using same, and provides a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same, which include a first reactant linked to a fluorescent substance and a second reactant linked to a reflective light substance that are applied as reactants for detecting a target analyte in a biosample, thereby enabling both fluorescence detection and reflected light detection of the target analyte in one reaction region so as to improve diagnosis accuracy, and that can be selectively applied to a fluorescent-type immunoanalytical diagnostic device or a reflective-type immunoanalytical diagnostic device according to the needs of a user so as to increase ease of use, and can detect two target analytes through fluorescent light and reflective light in one reaction region so as to enable multiplex analysis by means of a simple and miniaturized structure having one reaction region.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
4.
LATERAL FLOW ASSAY DEVICE FOR DIAGNOSING TRAUMATIC BRAIN INJURY USING TIME-RESOLVED FLUORESCENCE ANALYSIS AND METHOD FOR DIAGNOSING TRAUMATIC BRAIN INJURY USING THE SAME
Provided is a lateral flow assay device capable of detecting a traumatic brain injury marker including a sample pad into which a blood sample containing a traumatic brain injury marker is injected, an adsorption pad including a probe which is mixed to the marker when the traumatic brain injury marker moves from the sample pad to form a traumatic brain injury marker complex, and a porous film which fluid-communicates with the adsorption pad and capillary-migrates the traumatic brain injury marker complex from the adsorption pad to a detection line, in which the probe includes a capture antibody consisting of an antibody labeled with a specific binding material specifically binding to the traumatic brain injury marker and a detector antibody consisting of an antibody labeled with a fluorescent material having a relatively long emission lifetime of 1 microsecond or more, and a mixture of at least two different kinds-origin antibodies is used as the antibody labeled with the specific binding material or the fluorescent material.
The present disclosure relates to a sample solution heating apparatus for ex vivo diagnosis, and provided is a sample solution heating apparatus for ex vivo diagnosis, the apparatus: injecting a heating body into a reaction container in which a sample solution is stored and induction-heating the heating body by means of a primary induction coil, so as to directly transfer, through the heating body in the sample solution, heat to the sample solution without additional heat transfer media, thereby minimizing heat loss, and thus can rapidly heat the sample solution so as to enable more rapid diagnosis, and can improve energy efficiency; and induction-heating the heating body inside the reaction container and, simultaneously, rotating same by using magnetic force, so as to perform a stirring function, in addition to a simple heating function, on the sample solution, thereby enabling more rapid and accurate ex vivo diagnosis.
Provided in the present invention is a reference cassette for a fluorescence immunoassay diagnostic device, the cassette having, arranged in a case, fluorescent glass capable of maintaining fluorescence characteristics to be constant without causing degeneration, so as to accurately provide reference measurement information about the fluorescence detection amount during testing of the measurement accuracy of the fluorescence detection of the immunoassay diagnostic device, so that testing accuracy can improve, preventing decrease in measurement accuracy and being semi-permanently usable since the denaturation or deterioration of the fluorescent glass does not occur even if the cassette is used continuously, and providing a mask having a slit so as to limit the area of the fluorescent glass to be externally exposed to a specific area, thereby generating the type of fluorescence that is the same as that of a reaction area of a sample strip to be actually used, and thus more accurate reference measurement information can be provided.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 21/84 - Systems specially adapted for particular applications
7.
LATERAL FLOW ASSAY DEVICE FOR TRAUMATIC BRAIN INJURY DIAGNOSIS USING TIME-RESOLVED FLUORESCENCE ANALYSIS, AND METHOD FOR DIAGNOSING TRAUMATIC BRAIN INJURY BY USING SAME
A lateral flow assay device for detecting a traumatic brain injury marker according to an embodiment of the present invention comprises: a sample pad into which a blood sample containing a traumatic brain injury marker is injected; an adsorption pad comprising a probe which is mixed with the marker when the traumatic brain injury marker migrates from the sample pad, to form a traumatic brain injury marker complex; and a porous membrane which is in fluid communication with the adsorption pad and allows capillary movement of the traumatic brain injury marker complex from the adsorption pad to a detection line, wherein the probe comprises: capture antibodies consisting of antibodies labeled with a specific binding material that specifically binds to the traumatic brain injury marker; and detector antibodies consisting of antibodies labeled with a fluorescent material with a relatively long emission lifetime of 1 microsecond or greater, and, as the antibodies labeled with a specific binding material or a fluorescent material, a mixture of antibodies derived from at least two different species is used.
The present invention relates to a sample solution heating apparatus for ex vivo diagnosis, and provided is a sample solution heating apparatus for ex vivo diagnosis, the apparatus: injecting a heating body into a reaction container in which a sample solution is stored and induction-heating the heating body by means of a primary induction coil, so as to directly transfer, through the heating body in the sample solution, heat to the sample solution without additional heat transfer media, thereby minimizing heat loss, and thus can rapidly heat the sample solution so as to enable more rapid diagnosis, and can improve energy efficiency; and induction-heating the heating body inside the reaction container and, simultaneously, rotating same by using magnetic force, so as to perform a stirring function, in addition to a simple heating function, on the sample solution, thereby enabling more rapid and accurate ex vivo diagnosis.
The present invention relates to an immunoassay test strip using a capacitive sensor, and provides an immunoassay test strip using a capacitive sensor, wherein immunoassay diagnosis is performed by detecting capacitance changes that occur as target substances are captured in a reaction region, and it is thus unnecessary to use a separate light source device to detect the substances captured in the reaction region. Accordingly, the overall size of an immunoassay diagnostic device can be miniaturized, the structure thereof can be simplified, and the detection accuracy can be further improved by preventing detection errors caused by the external environment during light detection.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
G01N 33/558 - ImmunoassayBiospecific binding assayMaterials therefor using diffusion or migration of antigen or antibody
10.
METHOD FOR MANUFACTURING TEST STRIP FOR MULTIPLEX IMMUNOASSAY ANALYSIS, AND TEST STRIP MANUFACTURED USING SAME
The present invention relates to a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same. The present invention relates to a test strip for multiplex immunoassay analysis and a multiplex immunoassay analysis device using same, and provides a method for manufacturing a test strip for multiplex immunoassay analysis and the test strip manufactured using same, which include a first reactant linked to a fluorescent substance and a second reactant linked to a reflective light substance that are applied as reactants for detecting a target analyte in a biosample, thereby enabling both fluorescence detection and reflected light detection of the target analyte in one reaction region so as to improve diagnosis accuracy, and that can be selectively applied to a fluorescent-type immunoanalytical diagnostic device or a reflective-type immunoanalytical diagnostic device according to the needs of a user so as to increase ease of use, and can detect two target analytes through fluorescent light and reflective light in one reaction region so as to enable multiplex analysis by means of a simple and miniaturized structure having one reaction region.
Provided is a fluid analysis apparatus and a method of controlling the same. The fluid analysis apparatus include an actuator provided on a part of the fluid analysis apparatus, a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated, a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, and a controller configured to control an operation of the actuator based on the optical signal detected by the measurement portion such that the light transmitted from the measurement portion passes through a central portion of the well to perform an accurate inspection on the fluid sample.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 21/85 - Investigating moving fluids or granular solids
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 33/487 - Physical analysis of biological material of liquid biological material
The present invention relates to a diagnostic apparatus for an immunoassay, and provides a diagnostic apparatus for an immunoassay, whereby, without separately moving a sample strip or an optical module, a mask, having a slit part formed, is simply disposed, and the position of the slit part is altered, and thus a testing light may be accurately irradiated on a reaction region of the sample strip, and fluorescence or a reflected light, occurring from the reaction region of the sample strip, may be accurately detected, and thus diagnostic accuracy and convenience of use may be improved therethrough.
The present invention relates to a test strip for multiplex immunoassay analysis and a multiplex immunoassay analysis device using same, wherein, as reactants for exploring a target analyte in a biosample, a first reactant linked to a fluorescent substance and a second reactant linked to a reflective light substance are applied, thereby enabling both fluorescence analysis and reflective analysis of the target analyte in one reaction region and improving diagnosis accuracy. In addition, the reactants can selectively be applied to a fluorescent-type immunoanalytical diagnostic device or a reflective-type immunoanalytical diagnostic device according to the needs of a user, thereby increasing ease of use, and in one reaction region, two target analytes may be inspected through fluorescent light or reflective light, thus providing a multiplex immunoassay test strip and immunoassay analysis device using same with a simple and miniaturized structure having one reaction region.
The present invention relates to an immunoassay device. An immunoassay device according to an embodiment of the present invention may comprise an assay case which has a predetermined space formed therein, has, in one side surface thereof, a strip insertion hole through which a test strip is inserted, the test strip being capable of performing a test for a reactant for detecting a target analyte of a biological sample, and has, in the top surface thereof, an assay hole through which a mobile terminal is securely mounted, the mobile terminal being for performing an immunoassay on detection light generated from the test strip, by using an image acquired by imaging the detection light generated by test light irradiated to the test strip. According to the present invention, by inserting the test strip into the assay case, irradiating the inserted test strip with the test light, and imaging light reflected by the irradiated test light to perform an assay, there is an effect whereby diagnosis results obtained through the test strip can be conveniently analyzed.
The present invention provides a method for operating a diagnostic device, the method comprising the steps of: putting a sample including a reactant into a reaction well; pouring a buffer solution into the reaction well; reacting the reactant with conjugates in the reaction well to form a reaction product; removing the buffer solution from the reaction well; and measuring the reaction product.
The present invention comprises: pressing a buffer container above a crushing part; crushing a first separation membrane of the buffer container by means of the crushing part; and supplying a buffer solution into the crushing part through an inlet opening of the crushing part. Supplying the buffer solution through the inlet opening comprises lifting the first separation membrane to a protrusion part which protrudes from a main wall of the crushing part so as to separate the top surface of the main wall and the first separation membrane from each other.
Provided in the present invention is a reference cassette for a fluorescence immunoassay diagnostic device, the cassette having, arranged in a case, fluorescent glass capable of maintaining fluorescence characteristics to be constant without causing degeneration, so as to accurately provide reference measurement information about the fluorescence detection amount during testing of the measurement accuracy of the fluorescence detection of the immunoassay diagnostic device, so that testing accuracy can improve, preventing decrease in measurement accuracy and being semi-permanently usable since the denaturation or deterioration of the fluorescent glass does not occur even if the cassette is used continuously, and providing a mask having a slit so as to limit the area of the fluorescent glass to be externally exposed to a specific area, thereby generating the type of fluorescence that is the same as that of a reaction area of a sample strip to be actually used, and thus more accurate reference measurement information can be provided.
A fluid test cartridge, a fluid test apparatus, and a method for controlling the same. The fluid test apparatus includes a housing, and a fluid test cartridge that is accommodated in the housing. The fluid test cartridge includes at least one chamber in which a fluid sample to be tested and a drying reagent can be accommodated. The fluid test apparatus includes a light emitter configured to emit light to the at least one chamber, a light sensor, and a processor configured to detect a concentration of a first material in the fluid sample. The drying reagent includes a non-metallic particle bound to a second material that specifically binds to the first material. Tests can thus be carried out over a wider range of wavelengths, and testing errors can be reduced.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 21/82 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
A blood testing apparatus includes an analyzer configured to analyze blood components of an animal that are included in a test medium; an output device configured to display analysis results of the blood components; and a controller configured to determine a species of the animal based on at least one from among types of the blood components and the analysis results of the blood components and control the output device to display the determined species of the animal.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 33/80 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood groups or blood types
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
A fluid analysis cartridge having an improved structure in order to increase test reliability, and a fluid analysis apparatus including the same are disclosed. The fluid analysis apparatus comprises: a housing having a fluid supply part for supplying a fluid sample, and a filter member arranged such that the fluid sample supplied to the fluid supply part passes therethrough; a fluid analysis cartridge having a test unit that is connected to the housing so that the fluid sample that has passed through the filter member can be introduced and a test can be performed; and a pressure member that is arranged to pressurize the fluid analysis cartridge in order to move the fluid sample supplied to the fluid supply part to the test unit, wherein the test unit includes a first panel that has a first inflow part facing the filter member, and a second panel that is arranged to face the first panel and that has a second inflow part corresponding to the first inflow part, and the first inflow part may have a smaller width than the second inflow part.
A fluid analysis cartridge with improved test reliability and an associated fluid analysis cartridge assembly are disclosed herein. A fluid analysis cartridge assembly includes a sample collecting member having a sample collecting chamber and a fluid analysis cartridge configured to be connected to the sample collecting member. The fluid analysis cartridge includes a sample receiving chamber configured to receive a sample collected by the sample collecting member and at least one hole arranged on one side of the sample receiving chamber and opened by connection of the sample collecting member to the fluid analysis cartridge to the at least one hole. The sample receiving chamber stores a buffer solution to be mixed with the sample.
A sample test method, microfluidic device, and test device efficiently and accurately compensates for interference of an interfering substance present in a sample using optical measurement without addition of a separate reagent for detecting the interfering substance. The sample test method includes: measuring an optical characteristic value of a target substance present in a sample; measuring an optical characteristic value of an interfering substance present in the sample; and determining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
23.
Test apparatus and target measurement method using the same
A test apparatus and method for measuring a concentration of a target by correcting for an impact of hemoglobin are provided. The target measurement method includes measuring an absorbance of hemoglobin in a sample, measuring an absorbance of a target in the sample, determining variation of the absorbance of the target according to the measured absorbance of the hemoglobin, and correcting the absorbance of the target by subtracting the determined variation of the absorbance of the target from the measured absorbance of the target.
Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.
A test apparatus for measuring the temperature of a reactor using a thermochromic pigment, and a method for controlling the test apparatus are disclosed, based on a technology for irradiating light of different wavelengths on a thermochromic pigment accommodated in a reactor and estimating temperature of the reactor using a difference between absorbance values corresponding to the light of the different wavelengths. The test apparatus includes at least one light emitter configured to irradiate light of different wavelengths onto a chamber included in the reactor, a light receiver configured to receive the light that propagates through the chamber, and a controller configured to measure absorbance values of the thermochromic pigment in correspondence to the different wavelengths of the light, to calculate a difference between the measured absorbance values, and to determine a temperature of the reactor in correspondence to the calculated difference between the absorbance values.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01K 11/16 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance of organic materials
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
A fluid analysis cartridge includes a reference well including a macromolecular coloring reagent having an optical characteristic that varies according to a thickness of the reference well, and a test well including a test reagent having an optical characteristic that varies according to a concentration of a component of a fluid sample that reacts with the test reagent and a thickness of the test well.
A fluidic sample test apparatus has a mounting part such that the temperature of a fluidic sample, which is inserted into the mounting part, is uniformly maintained. The fluidic sample test apparatus includes a main body having a mounting part into which a sample cartridge is inserted, a metal panel disposed on one surface of the mounting part, and a printed circuit board (PCB) disposed on another surface of the mounting part facing the one surface. One side of the metal panel is in contact with the PCB.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Litmus paper; reagent paper (other than for medical or
veterinary purposes); nitrate paper; test paper, chemical;
chemical reagents (other than for medical purposes); in
vitro diagnostic reagents for scientific or research use;
reagents for scientific or research use; reagents for
scientific or medical research use; diagnostic preparations
for scientific or research use; chemical reagents for
scientific or laboratory purposes; reagents for medical
research; reagents for use in scientific apparatus for
chemical or biological analysis; reagent paper for
inspection (other than for medical or veterinary purposes);
test paper (other than for medical or veterinary purposes). Diagnostic test reagents for medical purposes; in vitro
diagnostic preparations for medical purposes; diagnostic
biomarker reagents for medical purposes; analytical reagents
for medical apparatus used for in vitro diagnosis; in vitro
diagnostic reagents for medical purposes; medical diagnostic
test strips; test paper or test strips for in vitro
diagnosis; test paper or test strips for analyzing
biological sample; reagents for medical or veterinary
purposes; chemical reagents for medical purposes. Light measuring devices; electronic optical sensors;
bio-sensors; biochip inspectors; equipment and apparatus for
fluorescent signal analysis; equipment and apparatus for
fluorescent signal detection; equipment and apparatus for
absorption measurement; diagnostic chips for scientific
laboratory use; biochip analyzing apparatus; cell chip
inspectors; biochip sensors; DNA chips. Medical diagnostic apparatus and instruments; diagnostic
apparatus for medical purposes; medical absorption analysis
apparatus; immunoassay apparatus for medical purposes; in
vitro diagnosis cartridge for medical purposes; medical
apparatus and instruments other than for dental purposes;
medical apparatus and instruments in the fields of clinical
diagnostic; diagnostic apparatus and instruments for medical
purposes; cartridges for medical purposes; test equipment
for medical use; immunofluorescence analysis apparatus for
medical purposes; in vitro diagnosis apparatus for medical
purposes; analytical apparatus for automatic analysis of
biological sample for medical purposes; apparatus for
fluorescent signal processing for medical purposes;
apparatus for fluorescent signal analysis for medical
purpose; medical immunoassay apparatus; apparatus for use in
medical analysis; diagnostic kits consisting of medical
devices and apparatus; immunoassay cartridge for in vitro
diagnosis for medical purpose; cartridge for analyzing
biological sample for medical purpose; immunoassay cartridge
for medical purposes; equipment and apparatus for testing
biological sample for medical purpose.
A specimen inspection apparatus into which a specimen transporting apparatus is inserted, the specimen inspection apparatus including: a platform including an upper plate and a lower plate disposed to face each other and to be spaced apart from each other by a predetermined distance; an injection part provided in the upper plate, a front end of the specimen transporting apparatus being inserted into the injection part; an introduction part connected to the injection part and provided between the upper and lower plate; and a plurality of stepped parts provided in the introduction part.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
[ Litmus paper; reagent paper, other than for medical or veterinary purposes; nitrate paper; test paper, chemical; chemical reagents, other than for medical purposes; in vitro diagnostic reagents for scientific or research use; reagents for scientific or research use; reagents for scientific or medical research use; diagnostic preparations for scientific or research use; chemical reagents for scientific or laboratory purposes; reagents for medical research; reagents for use in scientific apparatus for chemical or biological analysis ; reagent paper for inspection other than for medical or veterinary purposes; chemically-treated non-medical test paper for testing blood ] [Diagnostic test reagents for medical purposes; in vitro diagnostic preparations for medical purposes; diagnostic biomarker reagents for medical purposes; analytical reagents for medical apparatus used for in vitro diagnosis; in vitro diagnostic reagents for medical purposes; medical diagnostic test strips for testing blood; test paper or test strips for medical in vitro diagnosis; test paper or test strips for analyzing biological sample for medical purposes; reagents for medical or veterinary purposes; chemical reagents for medical purposes ] [ Light measuring devices; electronic optical sensors; bio-sensors, namely, sensors for sensing blood; electronic equipment for inspection of biochips; non-medical electronic equipment and apparatus for fluorescent signal analysis; non-medical electronic equipment and apparatus for fluorescent signal detection; non-medical electronic equipment and apparatus for light absorption measurement; diagnostic chips for scientific laboratory use; biochip analyzers, not for medical purposes; electronic equipment for inspection of cell chips; biochip sensors for research or scientific purposes; DNA chips ] Medical diagnostic apparatus and instruments for testing blood; [ diagnostic apparatus for medical purposes for testing urine; ] light absorption analysis apparatus for medical purposes; [ immunoassay apparatus for medical purposes, namely, apparatus for testing immune response between antigens and antibodies using fluorescence; in vitro diagnosis cartridge for medical purposes, namely, cartridge for testing immune response between antigens and antibodies using fluorescence; medical apparatus and instruments, other than for dental purposes, for testing nasal discharges; ] cartridges for medical purposes, namely, cartridge for testing blood; medical equipment for testing blood; [ immunofluorescence analysis apparatus for medical purposes; in vitro diagnosis apparatus for medical purposes for testing nasal discharges; ] analytical apparatus for automatic analysis of biological sample for medical purposes; [ apparatus for fluorescent signal processing for medical purposes; apparatus for fluorescent signal analysis for medical purpose; apparatus for use in medical analysis, namely, apparatus for testing immune response between antigens and antibodies using fluorescence; ] diagnostic kits consisting of medical devices and apparatus, namely, diagnostic kits for testing blood; [ immunoassay cartridge for in vitro diagnosis for medical purpose; ] cartridge for analyzing biological sample for medical purpose; [ immunoassay cartridge for medical purposes; ] equipment and apparatus for testing biological sample for medical purpose
31.
Method for controlling a test apparatus in response to external room conditions and reaction device storage conditions
A test apparatus and a method for controlling the same are provided. The test apparatus may receive information about a reaction device, information about a storage environment, and external environment information from a storage storing a sample and a sensor sensing the external environment of the test apparatus. The test apparatus may perform a variety of control actions for testing the sample based on a temperature of and around the reaction device, resulting in increased reliability of the test result.
Disclosed herein are a reactor, a test apparatus, and a test method, which measure, when a material included in a sample acts as an interfering material with respect to estimating a concentration of a target material, a concentration of the interfering material, and correct an estimated concentration of the target material based on the concentration of the interfering material, thereby improving the reliability and accuracy of the concentration of the target material. The reactor includes: a target material detecting chamber in which a first reagent that includes a first material that is activated by a target material is contained; a first material detecting chamber in which a second reagent that includes the target material is contained; an inlet hole into which a sample is injected; and a channel configured to connect the inlet hole, the target material detecting chamber, and the first material detecting chamber to each other.
G01N 15/06 - Investigating concentration of particle suspensions
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
33.
Microfluidic device and method of detecting sample supplied to the same
A microfluidic device includes a chamber configured to accommodate a sample and air, and a detection device provided with a light emitter configured to emit light towards the chamber on a light transmission path and a light receiver configured to receive the light, and further configured to measure an optical density of the chamber to determine whether the sample is accommodated in the chamber based on the received light. A boundary between the sample and the air accommodated in the chamber is provided on the light transmission path.
Disclosed herein are a structure for optical analysis that is capable of optically analyzing a small amount of a sample and an ink composition for manufacturing the same. A structure for optical analysis includes a support and an ink structure coupled to the support and configured to form a chamber on one surface of the support. The ink structure includes a first ink structural component configured to form a body of the ink structure and a second ink structural component formed at a lower portion of a side surface of the first ink, such that the first ink structural component and the second ink structural component have different slopes with respect to a direction of a center of the chamber.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
A test apparatus and a control method thereof are provided. The test apparatus is configured to test a sample in a reactor. The test apparatus includes at least one light emitter configured to emit light to chambers of the reactor, a light receiver configured to receive light passed through the chambers while scanning the chambers, and a processor configured to determine a position or an area of a chamber among the chambers, based on light receiving positions of the light receiver, and respective intensities of the received light. The processor is further configured to measure an optical density of light passed through the determined position or the determined area of the chamber.
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
A test device and a method for controlling the test device are disclosed. After a test is interrupted due to a malfunction of the test device, the test device continuously performs the interrupted testing. The test device for testing a biological material includes: a memory configured to store information which relates to progress of a test; and a controller which, if the test is interrupted due to a malfunction of the test device, is configured to continue performance of the test by using the information which relates to the test progress which is stored in the memory.
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
37.
Method and system for implementing alarms for medical device through mobile device
Provided are a method and system for implementing alarms for a medical device through a mobile device. The method includes: storing details of examination of a specimen (hereinafter, referred to as examination details) in the medical device, wherein the storing is performed by the medical device; accessing the medical device and establishing a connection with the medical device, wherein the accessing and the establishing of the connection is performed by the mobile device; reading the examination details stored in the medical device, wherein the reading is performed by the mobile device; analyzing the read examination details, wherein the analyzing is performed by the mobile device; and implementing an alarm if the result of analysis satisfies a predetermined criterion, wherein the implementing is performed by the mobile device.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
An in-vitro diagnostic apparatus includes a loading unit which receives a test medium including a test object; a first clock including first time information that is set as a standard clock time and used to determine whether an expiration date of the test medium has passed; a second clock including second time information that can be set as an arbitrary time; a sensor which acquires the expiration date of the test medium; a controller which determines whether the expiration date of the test medium has passed, based on the first time information; and an analyzer which analyzes the test object based on the second time information when it is determined that the expiration date of the test medium has not yet passed.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A sample test method, microfluidic device, and test device efficiently and accurately compensates for interference of an interfering substance present in a sample using optical measurement without addition of a separate reagent for detecting the interfering substance. The sample test method includes: measuring an optical characteristic value of a target substance present in a sample; measuring an optical characteristic value of an interfering substance present in the sample; and determining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
Provided is a fluid analysis cartridge configured to analyze a fluid specimen, a fluid analysis sheet forming the same and a method of manufacturing the fluid analysis cartridge. The fluid analysis sheet includes at least one cut out part configured to form an intermediate layer of an inspection substrate, the cut out part including a flow passage structure including an inlet part in which a fluid is introduced and an inspection part in which the fluid is introduced to react with a reagent; and wherein the cut out part is further configured to include a first end adjacent to the inspection part and a second end adjacent to the inlet part, and wherein a minimum distance between the first end and the flow passage structure is at least 1 mm.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
41.
Blood testing apparatus and blood testing method thereof
A blood testing apparatus includes a loader configured to receive a test medium, the test medium including a test object to be tested; a controller configured to perform control to operate the loader to receive the test medium in response to receiving an input of a trigger signal indicating a test start in an emergency mode; a display configured to display a user interface screen indicating the emergency mode; and an analyzer configured to automatically start analysis of the test object under the control of the controller when the test medium is received.
Disclosed herein are a test apparatus that photographs a home mark of a microfluidic apparatus by using a camera and determining a position of a home of the microfluidic apparatus by using the camera, and a control method thereof. The method of controlling a test apparatus includes photographing a microfluidic apparatus at a predetermined frame rate by using a camera of the test apparatus while the microfluidic apparatus is rotating at a predetermined speed, acquiring a capture image which includes a home mark of the microfluidic apparatus among a plurality of images acquired by the camera, and acquiring information which relates to an encoder of the test apparatus and which corresponds to the home mark of the capture image and determining a position of a home of the microfluidic apparatus based on the acquired information.
Disclosed herein is a microfluidic device, which includes a platform, at least one chamber provided in the platform to accommodate a sample, and at least one channel configured to couple the chambers to each other. The at least one chamber includes a detection chamber configured to detect the sample, and the microfluidic device further includes a light blocking portion configured to prevent external light from entering the detection chamber so as to prevent occurrence of errors in detection of the sample in the detection chamber. The microfluidic device can be useful for preventing the occurrence of detection errors which might otherwise be caused by interference of external light. The microfluidic device may also be useful for reducing an inspection time and for miniaturizing microfluidic devices. Further, the microfluidic device may be useful for preventing contaminants from entering the detection chamber.
Disclosed are a sample inspection apparatus and a control method thereof. The sample inspection apparatus includes a housing, a cartridge insertable into one side of the housing and configured to receive a sample, a pressing member disposed within the housing and configured to press the cartridge to inspect the sample, a fluid storage part configured to transfer a fluid to the pressing member so that the pressing member presses the cartridge, and a fluid supply part configured to supply the fluid into the fluid storage part.
Disclosed are an analysis device and a method of determining a mounted state of a cartridge mounted in the analysis device. The analysis device includes: a mounting unit configured to mount a cartridge on which at least one well for containing a specimen is formed; a measuring unit configured to measure at least one signal corresponding to the at least one well formed on the cartridge; and an operation processor configured to process the at least one measured signal with respect to the at least one well measured by the measuring unit, wherein the operation processor determines a mounted state of the cartridge based on the at least one measured signal with respect to the at least one well formed on the cartridge.
Provided are a method and system for transmitting an examination result of a specimen from a medical device to a destination. The method of transmitting the examination result from the medical device to the destination includes: examining the specimen by using the medical device; receiving destination information indicating the destination to which the examination result will be transmitted, wherein the receiving is performed by the medical device; and transmitting the examination result to the destination corresponding to the destination information, wherein the transmitting is performed by the medical device.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
H04L 29/08 - Transmission control procedure, e.g. data link level control procedure
H04W 8/18 - Processing of user or subscriber data, e.g. subscribed services, user preferences or user profilesTransfer of user or subscriber data
G06Q 50/24 - Patient record management (processing of medical or biological data for scientific purposes G06F 19/00)
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
47.
Optical detection apparatus and method of compensating detection error
An optical detection apparatus for measuring detection chambers of a specimen cartridge includes: a light source unit including light sources which are arranged along a scan line on which the detection chambers are aligned to be scanned, and configured to emit light rays to the detection chambers; and an optical detector configured to detect the light rays having passed through corresponding detection chambers disposed on the scan line. The light sources include main wavelength light sources which are used for measuring samples disposed in the detection chambers, and a sub-wavelength light source which is used for correcting a measuring error.
Disclosed herein are a test apparatus of a fluidic sample, which tests the fluidic sample, and a control method thereof. The test apparatus of the fluidic sample includes a housing, an installing member in which a cartridge receiving a fluid is inserted, a pressing member which is disposed in the housing to press the cartridge and perform an inspection of the fluid, a driving unit of which at least a part is coupled to the pressing member so as to movably drive the pressing member, and a sensing unit of which at least a part is opposite to the driving unit so as to sense a position of the driving unit. According to the present invention, since the sensing unit can recognize the position of the driving unit, the pressing member can apply uniform pressure to the cartridge.
Provided is a portable diagnostic test apparatus including: an accommodation portion including an outer side, an inner side, and an accommodation space provided on the inner side; a hinge; and a main body coupled to the accommodation portion by the hinge, where the portable diagnostic test apparatus is configured to be opened and closed by rotating one of the accommodation portion and the main body about the hinge, and where the main body is configured to obtain a result of a measurement based on data collected from drawn blood. The main body and/or the accommodation portion includes at least one strip keeping portion configured to store at least one strip. The at least one strip keeping portion may include: a housing; a discharge portion; and a first movement portion configured to move one of the strips to the discharge portion.
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variablesInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/151 - Devices for taking samples of blood specially adapted for taking samples of capillary blood, e.g. by lancets
A61B 5/157 - Devices for taking samples of blood characterised by integrated means for measuring characteristics of blood
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A test apparatus, which may compare detection data of a detector with reference data and correct a positional error in the detector due to the failing of a motor, and a method of controlling the same are provided. The test apparatus includes a detector configured to irradiate light to a plurality of chambers of a reaction device and detect a detection target, a motor configured to move the detector such that light is irradiated to the plurality of chambers, and a controller configured to compare detection data of the detector regarding the reaction device with reference data, determine a positional error in the detector, and correct the positional error.
Provided is a fluid analysis cartridge that performs a test on a fluid sample. The fluid analysis cartridge includes: a testing part configured to receive a fluid sample and configured to perform a test on the fluid sample; a housing including at least one supply hole configured to supply the fluid sample to the testing part; a filtering part that is disposed between the at least one supply hole and the testing part and is configured to filter a particular material included in the fluid sample; and at least one stepped part provided on a surface of the housing facing the filtering part and that forms a gap between the filtering part and the surface of the housing.
Provided are a method and system for implementing alarms for a medical device through a mobile device. The method includes: storing details of examination of a specimen (hereinafter, referred to as examination details) in the medical device, wherein the storing is performed by the medical device; accessing the medical device and establishing a connection with the medical device, wherein the accessing and the establishing of the connection is performed by the mobile device; reading the examination details stored in the medical device, wherein the reading is performed by the mobile device; analyzing the read examination details, wherein the analyzing is performed by the mobile device; and implementing an alarm if the result of analysis satisfies a predetermined criterion, wherein the implementing is performed by the mobile device.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
53.
Method and system for transmitting result of examination of specimen from medical device to destination through mobile device
Provided are a method and system for transmitting the result of examination of a specimen (hereinafter referred to as an examination result) from a medical device to a destination through a mobile device. The method of transmitting the examination result from the medical device to the destination through the mobile device includes: examining the specimen by using the medical device; receiving the examination result from the medical device, wherein the receiving is performed by the mobile device; receiving destination information indicating the destination to which the examination result will be transmitted, wherein the receiving is performed by the mobile device; and transmitting the examination result to the destination corresponding to the destination information, wherein the transmitting is performed by the mobile device.
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
H04B 7/26 - Radio transmission systems, i.e. using radiation field for communication between two or more posts at least one of which is mobile
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G06Q 50/24 - Patient record management (processing of medical or biological data for scientific purposes G06F 19/00)
Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber.
A sample analysis apparatus is provided with a structure for stopping rotation of a disc at a precise position. The sample analysis apparatus includes a disc configured to rotate on a rotation shaft and having at least one detection zone, an optical sensing apparatus configured to detect a reaction result at the at least one detection zone, at least one position determining protrusion provided on an exterior surface of the disc, a slider movably disposed to in a radial direction relative to the disc, and a stopper mounted to the slider and configured to stop rotation of the disc by blocking the at least one position determining protrusion.
A test apparatus in which detectors and objects to be detected are rotated at the same speed, and a control method thereof are provided. The test apparatus includes a rotation driving unit that includes a rotary shaft; a microfluidic device that is loaded on the rotary shaft and includes at least one object to be detected; a rotating member that is mounted on the rotary shaft and includes at least one detector to detect the objects of the microfluidic device; and a controller configured to operate the rotation driving unit such that the microfluidic device and the rotating member are rotated at the same speed on the rotary shaft.
Provided is a microfluidic apparatus including: a microfluidic structure for providing spaces for receiving a fluid and for forming channels, through which the fluid flows; and valves for controlling the flow of fluid through the channels in the microfluidic apparatus. The microfluidic structure includes: a sample chamber; a sample separation unit receiving the sample from the sample chamber and separating a supernatant from the sample by using a centrifugal force; a testing unit receiving the supernatant from the sample separation unit for detecting a specimen from the supernatant using an antigen-antibody reaction, and a quality control chamber for identifying reliability of the test.
A microfluidic apparatus having an additional chamber containing material configured to prevent cross contamination between reaction chambers contained therein, and a control method thereof are provided. The microfluidic apparatus includes a sample chamber configured to accommodate a sample, a plurality of reaction chambers each configured to accommodate a reagent, a distribution channel configured to distribute the sample into the plurality of reaction chambers, a mixture prevention chamber connected to the distribution channel and containing a mixture prevention material configured to prevent the reagents accommodated in the plurality of reaction chambers from being mixed with each other, and a valve disposed within the distribution channel and configured to open and close the distribution channel.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
An apparatus for separating components and a method of separating components using the apparatus are provided. The apparatus includes: a main chamber which contains a sample that is separated into a plurality of layers by a centrifugal force; a component separating chamber which is connected to the main chamber, and receives a specific layer including specific components among the plurality of layers; a first channel which connects the component separating chamber to the main chamber; and a first channel valve which is disposed in the first channel to control a liquid flowing through the first channel.
G01N 9/30 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity by using centrifugal effects
63.
Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device
A centrifugal force-based microfluidic device for nucleic acid extraction and a microfluidic system are provided. The microfluidic device includes a body of revolution; a microfluidic structure disposed in the body of revolution, the microfluidic structure including a plurality of chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structure transmitting the fluid using centrifugal force due to rotation of the body of revolution; and magnetic beads contained in one of the chambers which collect a target material from a biomaterial sample flowing into the chamber, wherein the microfluidic structure washes the magnetic beads which collect the target material, and separates nucleic acid by electromagnetic wave irradiation from an external energy source to the magnetic beads. The microfluidic system includes the microfluidic device; a rotation operating unit which rotates the body of revolution; and an external energy source which irradiates electromagnetic waves.
A microfluidic device having a chamber with a fluid discharge configuration is provided. The microfluidic device includes a platform including a chamber configured to accommodate a fluid therein. The chamber includes an inner sidewall and an outer sidewall disposed outwardly from the inner sidewall in a radial direction of the platform. The outer sidewall includes a first point located closest to a center of the platform, and a second point located farthest from the center of the platform. A distance from the center of the platform to an arbitrary third point on the outer sidewall between the first point and the second point increases from the first point to the second point, so that the fluid near the first point is guided to the second point by centrifugal force during rotation of the platform.
Provided are a particle measurement apparatus having a plurality of apertures arranged in series therein, and a particle measurement method using the same to statistically analyze multiple signals generated when a particle passes through the plurality of apertures, thus acquiring more accurate information on particles. The particle measurement apparatus includes a plurality of aperture members arranged in series, a plurality of electrodes to form an electric field within the plurality of aperture members, and an analyzer for statistically analyzing multiple electrical signals generated when a particle passes through the plurality of aperture members.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G01N 15/02 - Investigating particle size or size distribution
A test device having an internal temperature constantly maintained even when a voltage supplied to the test device is altered, and a control method thereof are provided. The test device includes a heater, a temperature sensor to sense an internal temperature of the test device, and a control part to control a current applied to the heater, in order to prevent a temperature of the heater from being varied due to voltage variation when the voltage supplied to the test device is altered.
A detecting device packing tray is provided which prevents a detecting device from being contaminated and damaged. The detecting device packing tray includes a tray main body configured to support a detecting device including a detection region to detect a reaction result. The tray main body includes a non-contact groove provided at a position corresponding to the detection region of the detecting device when the detecting device is supported by the tray main body so that the detection region does not contact the tray main body.
Assigning identifiers to a plurality of test devices to manage the test devices, and displaying the assigned identifiers on the test devices to distinguish the test devices.
G06F 15/00 - Digital computers in generalData processing equipment in general
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
69.
Method to determine presence of rotator and method to adjust optimal gain
A rotation driving system and a method to determine the presence of a rotator on a turntable are provided. The rotation driving system includes an encoder to detect rotation information of a motor, and a controller to determine whether or not a rotator is present on a turntable and also, to adjust a gain of the motor according to moment of inertia of the rotator.
H02K 29/08 - Motors or generators having non-mechanical commutating devices, e.g. discharge tubes or semiconductor devices with position sensing devices using magnetic effect devices, e.g. Hall-plates or magneto-resistors
Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.
A microfluidic device and method for measuring a level of cholesterol therewith are provided. The cholesterol measurement apparatus includes a microfluidic device including a plurality of chambers and at least one channel through which the plurality of chambers are interconnected. The plurality of chambers include a reaction chamber which contains a capture binder, a buffer chamber which contains an elution buffer and is connected to the reaction chamber, and at least one detection chamber which contains a cholesterol measurement reagent and is connected to the reaction chamber.
Provided is a microfluidic device and microfluidic system with the device. The microfluidic device includes a substrate; a channel formed in the substrate and in which a fluid can move; a valve controlling flow of a fluid flowing along the channel and including a phase transition material which can be melted by energy such as electromagnetic wave energy; and a lens disposed on the substrate and adjusting an irradiating region of the valve, onto which the energy is applied.
A microfluidic device having a delay structure and a sample testing apparatus including the microfluidic device are provided. The microfluidic device includes: a reaction chamber which contains a reagent capable of reacting with a sample; a distribution channel through which the sample is provided to the reaction chamber; an inlet channel through which the at least one reaction chamber is connected with the distribution channel; and a delay structure which is located between the at least one reaction chamber and the distribution channel, and delays movement of contents of the reaction chamber to the distribution channel.
Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.
The control method includes obtaining an assumed angle and an actual angle of each of the plurality of rotation angle detecting members, determining a first rotation angle detecting member, the assumed angle and the actual angle of which differ from each other, determining a second rotation angle detecting member having the actual angle closest to the assumed angle of the first rotation angle detecting member, resetting the given count value of the second rotation angle detecting member to a new count value of the first rotation angle detecting member, changing the actual angle of the first rotation angle detecting member via the new count value of the first rotation angle detecting member to reduce an angular error between the assumed angle and the actual angle of the first rotation angle detecting member.
G01R 33/032 - Measuring direction or magnitude of magnetic fields or magnetic flux using magneto-optic devices, e.g. Faraday
G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux
G01B 11/26 - Measuring arrangements characterised by the use of optical techniques for measuring angles or tapersMeasuring arrangements characterised by the use of optical techniques for testing the alignment of axes
Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber.
Provided is a biochemical analyzer including: a microfluidic device loading space including a microfluidic device supporting unit detachably supporting a microfluidic device including an electromagnetic radiation application region in which electromagnetic energy is applied; an energy source loading space including an energy source applying the electromagnetic energy to the electromagnetic radiation application region; and an isolation wall isolating the microfluidic device loading space and the energy source loading space to prevent heat transfer between the microfluidic device loading space and the energy source loading space and including a transparent window through which the electromagnetic energy can be transmitted. A method of controlling an internal temperature of the biochemical analyzer is also provided.
A apparatus for analyzing sample to prevent a sample from being stuck to a surface of the apparatus for analyzing sample in the course of being injected into the apparatus for analyzing sample. The apparatus for analyzing sample includes a platform having a disk shape. The platform includes chambers and channels, a sample inlet hole which is formed in an outer surface the platform and through which a sample is injected into the platform; an opening which is formed in the outer surface of the platform and through which a residual of the sample, present on the outer surface of the platform around the sample inlet hole, is introduced into a receiving space isolated from the chambers and channels; and a barrier which is formed on the outer surface of the platform around a portion of the opening to prevent the residual of the sample from moving past the opening in a radial outward direction of the platform.
Provided are a valve unit and a reaction apparatus having the valve unit. The valve unit includes a phase transition material, which melts and expands upon an application of the electromagnetic waves to the valve filler, and the valve filler is directed into the channel through the connection passage and closes the channel. The valve unit also includes heat generation particles, which are dispersed in the phase transition material and generate heat upon an application of electromagnetic wave energy.
A microfluidic system includes a microfluidic device including a chamber which contains a fluid sample, a channel which is connected to the chamber and through which the fluid sample flows, and a valve which controls flow of the fluid sample through the channel; an irradiation apparatus which irradiates electromagnetic energy; and a diffuser which diffuses and distributes the electromagnetic energy irradiated by the irradiation apparatus to an irradiation region of the microfluidic device.
A system recovery method and an apparatus supporting the same are disclosed. A software image is downloaded, and a system is loaded with the downloaded software image, and the system is recovered by a software image used before the updating, if the system loading fails.
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result
G06F 9/44 - Arrangements for executing specific programs
A normally open valve unit to close a channel, a microfluidic device equipped with the same, and a method of driving the valve unit are provided. The valve unit includes a valve substance including a phase transition material, a valve substance chamber which communicates with the channel and in which the valve substance is disposed, and a fusion structure formed in a section of the channel in which, wherein when the valve substance contained in the valve substance chamber is fused by applied energy and flows into the section of the channel in which the fusion structure is formed, and the valve substance is heated to melt the fusion structure and conduct fused bonding of the channel, thereby closing the channel.
A valve unit and an apparatus having the same include a plug which includes a phase change material in a solid state at a room temperature and a plurality of fine heat-dissipating particles dispersed in the phase change material. The fine heat-dissipating particles dispersed in the phase change material dissipate heat by absorbing an electromagnetic wave energy generated by electromagnetic wave radiation from the outside and block fluid flow in a path formed by a channel. As an external energy source irradiates an electromagnetic wave on the plug, the plurality of fine heat-dissipating particles dissipate heat and the phase change material becomes molten, thus opening the path to allow the fluid to flow.
A method and apparatus for controlling driving of a test device that analyzes a sample are provided. The method includes identifying a test device, executing a script containing a plurality of operations to be performed to analyze the sample contained in the test device, wherein the script includes a plurality of operation commands, wherein at least one operation command among the plurality of operation commands includes a conditional statement, and wherein at least one operation command among the plurality of operation commands is designated to be executed according to whether the conditional statement is satisfied.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A centrifugal force-based microfluidic device for the detection of a target biomolecule and a microfluidic system including the same are provided. The device includes a body of revolution; a microfluidic structure disposed in the body of revolution including chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structures transmitting fluid using centrifugal force due to rotation of the body of revolution; and beads disposed in the microfluidic structures, the beads having capture probes on the surfaces thereof which are selectively bonded with target protein; and a detection probe disposed in the microfluidic structures and selectively bonded to the target protein, and which includes a material required to express an optical signal, wherein the microfluidic structure mixes the beads, biological samples, and the detection probe to react and washes and separates the beads after the reaction.
G01N 9/30 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity by using centrifugal effects
86.
Remote medical diagnosis device including bio-mouse and bio-keyboard, and method using the same
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
87.
Bio-disc reading apparatus and assay method using same
Provided is a bio-disc reading apparatus for reading information including product authentication of a bio-disc and assay site of a bio-disc, and an assay method using same.
G01N 33/567 - ImmunoassayBiospecific binding assayMaterials therefor using specific carrier or receptor proteins as ligand binding reagent utilising isolate of tissue or organ as binding agent
88.
Thin film bio valve device and its controlling apparatus
A thin film bio valve device and an apparatus for controlling the thin film bio valve device are effectively applied in a valve structure of a thin film device, such as a lab-on-a-chip, a protein chip, or a DNA chip, for diagnosing and/or detecting a small amount of material in a fluid.
Provided is a microfluidic device that can automatically perform various types of biological blood analysis. In the microfluidic device, a specimen is centrifugally separated and the centrifugally separated specimen is diluted into various dilution ratios. Also, at least two reagents that are required for one reaction and that need to be separately stored are stored in separate chambers, and they are mixed when a reaction is needed. Thus, various conventional blood analyzing reagents can be used as they are or after being minimally processed in the microfluidic device.
Provided are a disc chucking method of preventing mis-chucking from occurring according to a state and direction of a disc loaded onto a tray when the tray is closed, and a disc driving apparatus for performing the disc chucking method. The method include: opening a tray on which a disc in which a first magnet is installed is loadable; moving a feeding unit to a position where attraction between a second magnet installed in the feeding unit and the first magnet is relatively low; and if the tray is closed, placing a center of the disc in a turn table.
Provided are a method and/or apparatus for measuring the concentration of a detection target using the transmission or reflection of light. The system includes an illumination unit disposed over a biodisc and configured to apply light to the detection target included in the biodisc and a camera module disposed below the biodisc and configured to measure the amount of light transmitted through the detection target.
A bio-disc device including new valve control means and fluid movement system, a bio-driver apparatus in which a controller disc including a controller for the bio-disc is installed, and an assay method using the same, which are suitable for labs-on-a-chips for various diagnostic assays, nucleic acid hybridization assays, and immunoassays, are provided. The bio-driver apparatus is compatible with general optical discs, including audio CDs, CD-Rs, game CDs, DVDs, etc., and the assay method is compatible with general optical disc drivers, including CD-ROMs, DVD players, etc. Thus, the bio-driver apparatus and the assay method offer and economical and convenient alternative to existing products. In addition, the bio-driver apparatus can be readily and easily applied in connection with a computer for remote diagnosis via the Internet.
Disclosed is a microfluidic sensor complex structure comprising a lower plate, a middle plate and an upper plate. A reference electrode, a working electrode and an electrode connection are formed on the lower plate. The middle plate comprises a microfluidic channel passage therein. The upper plate is overlaid on the middle plate so as to induce a capillary phenomenon on the microfluidic channel passage formed on in the middle plate. The microfluidic sensor complex structure allows the motion of a sample to be driven only by a capillary phenomenon, without additional operation, and allows an immune response, washing, and electrochemical analysis in one round once a sample is introduced thereinto. Hence, it requires only a short time period for measurement, is convenient to handle, and shows sensitivity and selectivity. Also, it can be produced on a mass scale because it can be formed of typical organic polymers using a simple method. Based on analytical electrochemistry, the microfluidic sensor complex structure can be used as a small-size sensor that can be applied to practice sites.
Provided are a method of measuring a concentration of a component in a biochemical sample such as serum, and a method of estimating the reliability of a test result using the method. The method of measuring a concentration of a component includes: preparing plural standard samples having at least one common component which has varying concentrations; measuring absorbances of the component in the standard samples at each of the concentrations for plural light beams having different wavelength bands; determining a regression equation of a relationship between the concentration of the component and the measured absorbances at plural wavelength bands; and applying the regression equation by measuring absorbances at the plural wavelength bands of the biochemical sample and applying the measured plural absorbances of the biochemical sample to the regression equation to calculate the concentration of the component.
G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
95.
Article for assaying target, comprising solid surface on which first binding member, blocking material, and second binding member are immobilized, and use thereof
Disclosed are an article for assaying a target, wherein the article includes a solid surface on which a first binding member, a blocking material, and a second binding member are immobilized, a method of manufacturing the article, and a method of detecting a target using the article.
Provided are a remote medical-diagnosis system including: a bio-disc or a biochip performing biological, chemical or biochemical reactions with a sample, and having a barcode or a RF IC; a bioanalytical device analyzing results of reactions performed by the bio-disc or the biochip and including a reader reading the barcode or the RF IC to authenticate the bio-disc or the biochip or recording the measured data to the RF IC regardless of a connection with a remote diagnosis server; a virtual doctor as a software in a user's terminal, the virtual doctor providing a user with guidelines and instructions as how to use the bioanalytical device, and providing the user with a consulting service, a diagnosis unit self-analyzing the measured data using mathematical calculations and outputing results of a diagnosis; a user's terminal providing the user with a consulting service from a medical expert or a virtual doctor; a medical expert's terminal providing the user with a consulting service; and a remote diagnosis server connecting the user with the medical expert during periodic medical consultations, connecting the user with the virtual doctor during non-periodic medical consultations, blocking connection between the user and the virtual doctor if a periodic medical consultations term has elapsed; and a method of performing the remote medical-diagnosis.
G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
97.
Lyophilizing tray employing reagent cartridge, lyophilizing system employing the same, and method of preparing lyophilized reagent
A method of manufacturing a lyophilized reagent, including mounting a plurality of reagent cartridges in which a liquid reagent is loaded in a tray including one or more tunnel-shaped first rails having opened end portions in a lengthwise direction and an opening formed in the top of the one or more first rails; closing the opened end portions, placing the tray in a lyophilizer and lyophilizing the liquid reagent according to a lyophilizing program.
F26B 11/18 - Machines or apparatus for drying solid materials or objects with movement which is non-progressive on or in moving dishes, trays, pans, or other mainly-open receptacles
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
A47G 29/00 - Supports, holders, or containers for household use, not provided for in groups or
98.
Microfluidic device using centrifugal force, method of manufacturing the microfluidic device and sample analyzing method using the microfluidic device
Provided is a microfluidic device including: a sample chamber; at least one analyzing unit receiving a sample from the sample chamber and detecting components contained in the sample according to a reaction of the sample and a reagent; and a denaturation detection chamber determining the storage condition of the microfluidic device, wherein the denaturation detection chamber accommodates a material whose light absorption changes according to the temperature and the water thereof.
Provided is a microfluidic apparatus including: a microfluidic structure for providing spaces for receiving a fluid and for forming channels, through which the fluid flows; and valves for controlling the flow of fluid through the channels in the microfluidic apparatus. The microfluidic structure includes: a sample chamber; a sample separation unit receiving the sample from the sample chamber and separating a supernatant from the sample by using a centrifugal force; a testing unit receiving the supernatant from the sample separation unit for detecting a specimen from the supernatant using an antigen-antibody reaction, and a quality control chamber for identifying reliability of the test.
A microfluidic device includes a sample chamber accommodating a sample, a first sample distribution unit connected to the sample chamber and receiving the sample, a sample transfer unit connected to the first sample distribution unit and forming a path for transferring the sample, and including a first connection unit connected to the first sample distribution unit and a second connection unit, wherein the distance from the center of rotation to the second connection unit is greater than the distance from the center of rotation to the first connection unit, a second sample distribution unit connected to the second connection unit and receiving the sample transferred via the sample transfer unit after filling the first sample distribution unit, and first and second analysis units respectively connected to the first and second sample distribution units and analyzing ingredients of the sample.
G01N 1/00 - SamplingPreparing specimens for investigation
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 9/30 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity by using centrifugal effects
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
F04B 19/00 - Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups
B01D 45/00 - Separating dispersed particles from gases or vapours by gravity, inertia, or centrifugal forces
F16K 3/00 - Gate valves or sliding valves, i.e. cut-off apparatus with closing members having a sliding movement along the seat for opening and closing
