Disclosed herein is an electrode film exhibiting high density and low tortuosity, along with an electrode-forming composition used to make the electrode film. Also disclosed is a method for making the electrode film, which comprises using a template component that can be removed after forming the electrode film to provide a hierarchical pore network throughout the electrode film. In addition to the template component and an electroactive material, some aspects of the disclosure utilize a binder. In some aspects, the binder becomes fibrillated during the method used to make the electrode, which further facilitates the hierarchical pore network in some aspects.
A functional electrical stimulation (FES) system includes a stimulation garment with electrodes arranged to contact skin of an anatomical region worn on the anatomical region, an FES stimulator, an FES control user interface (UI) device configured to present an FES control UI, and a hardware processor programmed to: set the FES system in a user-selected operating mode based on user inputs from the FES control UI, determine an operating mode-specific FES stimulation based at least on the user-selected operating mode, and control the FES stimulator to apply the operating mode-specific FES stimulation to the anatomical region of the user via the electrodes.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
3.
TECHNOLOGIES FOR INTEGRATED EPIGENOMIC EXPOSURE SIGNATURE DISCOVERY
Illustrative embodiments of technologies for integrated epigenomic exposure signature discovery are disclosed. According to one aspect, a computer-implemented method may comprise obtaining feature data from a plurality of epigenetic assays performed on samples from a population, wherein the samples comprise first samples corresponding to a first exposure state and second samples corresponding to a second exposure state different from the first exposure state, training a plurality of assay-level models to distinguish between the first and second exposure states, wherein each one of the plurality of assay-level models is trained using feature data from one of the plurality of epigenetic assays, and combining the plurality of assay-level models to build an exposure-level model configured to distinguish between the first and second exposure states based on a subset of the feature data.
G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids
G16B 5/00 - ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16B 25/00 - ICT specially adapted for hybridisationICT specially adapted for gene or protein expression
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
4.
AIRCRAFT SEEKER WINDOWS AND AIRCRAFT WINDOW SYSTEMS INCLUDING THE SAME
An approach to seeker windows for aircraft comprises a window layer comprising an IR transparent material, the window layer comprising a first side and a second side substantially opposite the first side; and a heating layer on the first side or the second side of the window layer, the heating layer configured to apply a heating profile to the window layer to reduce thermal shock imparted to the window layer when the seeker window is exposed to hypersonic flight conditions.
B32B 17/06 - Layered products essentially comprising sheet glass, or fibres of glass, slag or the like comprising glass as the main or only constituent of a layer, next to another layer of a specific substance
B32B 7/12 - Interconnection of layers using interposed adhesives or interposed materials with bonding properties
B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
B32B 9/04 - Layered products essentially comprising a particular substance not covered by groups comprising such substance as the main or only constituent of a layer, next to another layer of a specific substance
B32B 15/02 - Layered products essentially comprising metal in a form other than a sheet, e.g. wire, particles
H05B 3/84 - Heating arrangements specially adapted for transparent or reflecting areas, e.g. for demisting or de-icing windows, mirrors or vehicle windshields
H05B 3/86 - Heating arrangements specially adapted for transparent or reflecting areas, e.g. for demisting or de-icing windows, mirrors or vehicle windshields the heating conductors being embedded in the transparent or reflecting material
5.
METHOD AND SYSTEM FOR CONVERTING MIXED ALCOHOL COMPOSITION TO HYDROCARBON FUELS AND METHOD OF MAKING THE SAME
3+3+3+ mixed alcohol composition from a starting feedstock (front-end) and converting the composition to hydrocarbon fuels (back-end). Additional co-products also are prepared during the process that can be isolated and used as commodity chemicals in other processes and/or added back to the method to increase yields.
C10G 69/12 - Treatment of hydrocarbon oils by at least one hydrotreatment process and at least one other conversion process plural serial stages only including at least one polymerisation or alkylation step
C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
C10G 50/00 - Production of liquid hydrocarbon mixtures from lower carbon number hydrocarbons, e.g. by oligomerisation
6.
TECHNIQUES FOR GENERATING SYNTHETIC THREE-DIMENSIONAL REPRESENTATIONS OF THREATS DISPOSED WITHIN A VOLUME OF A BAG
In an approach to generating a synthetic three-dimensional (3D) X-ray volume, a first bag image of the plurality of bag images that includes an associated bag subvolume greater than a volume of a threat represented in a first threat image of the plurality of threat images is selected. An image is created based on inserting the threat of the first threat image into the associated bag subvolume of the first bag image.
In an optical carrier injection method, a pulsed optical beam having pulse duration of 900 fs or lower is applied on a backside of a substrate of an integrated circuit (IC) wafer or chip, and is focused at a focal point in an active layer on a frontside of the substrate. Photons of the optical beam are absorbed at the focal point by nonlinear optical interaction(s) to inject carriers. The pulsed optical beam may be applied using a fiber laser in which the fiber is doped with Yb and/or Er. An output signal may be measured, comprising an electrical signal or a light output signal produced by the IC wafer or chip in response to the injected carriers. By repeating the applying, focusing, and measuring over a grid of focal points in the active layer, an image of the IC wafer or chip may be generated.
Powder coating resins and coatings made using the powder coating resins are described. The powder coating resins are based on the use of C12 to C23 diacids. The C12 to C23 diacids are reacted with a reactant having an alcohol functionality and an amine functionality to form a carboxylic acid terminated polymer having ester and amide functionality. Alternatively, the C12 to C23 diacids are reacted with a reactant having an alcohol functionality and an amine functionality to form an intermediate polyol, which is then reacted with acetoacetic acid or an ester thereof to form an acetoacetate-terminated polymer.
Powder coating resins and coatings made using the powder coating resins are described. The powder coating resins are based on the use of C12 to C23 diesters. The C12 to C23 diesters are reacted with a reactant having an alcohol functionality and an amine functionality to form an intermediate polyol, followed by reaction with a diacid to a carboxylic acid terminated polymer having ester and amide functionality.
The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.
The present disclosure provides systems and processes to screen for SARS-CoV-2. This disclosure teaches specific (and different) workable ranges for starting materials in a screening process for different SARS-CoV-2 variants (e.g., the Washington isolate, Alpha variant, Gamma P.1 variant, Beta variant, Iota variant, Delta variant, Omicron BA.1 variants, etc.). As shown herein, each variant has a different combination of starting materials and incubation periods, which further demonstrates the unpredictability of success that is associated with the disclosed systems and the disclosed processes. To be clear, the general ELISA process is well known by those having skill in the art. However, what is neither well known nor intuitive are the specific parameters associated with different process steps within ELISA. Those specific parameters are the subject of this disclosure.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
12.
SYSTEMS AND METHODS FOR PREDICTING A CONDITION REQUIRING A LIFE-SAVING INTERVENTION INCLUDING LEVERAGING CONTEXTUAL INFORMATION AND INFORMATION ON RELIABILITY OF INPUT DATA STREAMS
To provide a life-saving intervention (LSI) recommendation, physiological data streams are acquired from a patient. Features are extracted from the physiological data streams. Statistical process control (SPC) is applied to the physiological data streams to generate SPC quality metric features for the physiological data streams. The SPC quality metric features are indicative of signal quality of the physiological data streams. The extracted features and the SPC quality metric features for the physiological data streams are combined, and a condition of the patient requiring an LSI is predicted based on the combination of the extracted features and the SPC quality metric features for the physiological data streams.
G06V 20/52 - Surveillance or monitoring of activities, e.g. for recognising suspicious objects
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
Embodiments provide metal batteries (e.g., lithium metal batteries), scaffolded collectors for anodes for such batteries, and methods for making such scaffolded collectors. One formation method includes electrospinning a polymeric material (e.g., polyimide) to form a nanomat, matrix or scaffold with opening or voids therein. The scaffold is treated to incorporate potassium ions which are then replaced by silver ions, which are then converted to silver seeds. The seeded scaffold receives copper via electroplating which is then followed by heat-treating to make the copper smooth and uniform. Openings within the heat-treated copper coated scaffold can then be loaded with anode material (e.g., lithium) and used as part of a metal battery. The copper coated scaffold without additional loading can also be used as current collector in anode-free metal batteries.
C23C 18/16 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by reduction or substitution, i.e. electroless plating
D04H 1/4382 - Stretched reticular film fibresComposite fibresMixed fibresUltrafine fibresFibres for artificial leather
D04H 1/728 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
D06M 11/83 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with metalsTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with metal-generating compounds, e.g. metal carbonylsReduction of metal compounds on textiles
D06M 101/30 - Synthetic polymers consisting of macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
An extruded polymer composite may include a polymer matrix. An extruded polymer composite may include and a filler content greater than about 65 wt % homogenously distributed about the polymer matrix.
The disclosure relates to rare earth element (REE) phosphates and methods for making the same. The REE phosphates can be formed by combining a REE sulfate with a phosphate source and a biological catalyst, for example an acid phosphatase.
A radio frequency (RF) aperture includes an array of electrically conductive tapered projections arranged to define a curved aperture surface, such as a semi-cylinder aperture surface, or a cylinder aperture surface (which may be constructed as two semi-circular aperture surfaces mutually arranged to define the cylinder aperture surface). The RF aperture may further include a top array of electrically conductive tapered projections arranged to define a top aperture surface. The top aperture surface may be planar, and a cylinder axis of cylinder aperture surface may be perpendicular to the plane of the planar top aperture surface. The RF aperture may further include baluns mounted on at least one printed circuit board, each having a balanced port electrically connected with two neighboring electrically conductive tapered projections of the array and further having an unbalanced port.
In an imaging method, a focal point of a focused optical beam is sequentially mechanically positioned at coarse locations in or on an integrated circuit (IC) wafer or chip. At each coarse location, a two-dimensional (2D) image or mapping tile is acquired by steering the focal point to fine locations on or in the IC wafer or chip using electronic beam steering and, with the focal point positioned at each fine location, acquiring an output signal produced in response to an electrical charge that is optically injected into the IC wafer or chip at the fine location by the focused optical beam. The 2D image or mapping tiles are combined, including stitching together overlapping 2D image or mapping tiles, to generate an image or mapping of the IC wafer or chip. The electronic beam steering may be performed using a galvo mirror. The set of coarse locations may span a three-dimensional (3D) volume.
G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
18.
System Evaluation via Multiplex Network Science and Multiscale System Dynamics
A multiplex network science (MNS) model represents infrastructure of an environment and an installation as a plurality of nodes connected by links, the links defining dependencies between the plurality of nodes. A multiscale system dynamics (MSD) model represents the installation as a plurality of nested subsystems and resource flows connecting the nested subsystems. A hybrid model integrating the MNS model and the MSD model is generated, the hybrid model linking the MNS model and MSD model via boundary conditions representing dependencies between the installation and the infrastructure of the environment. The hybrid model simulates an alteration to the infrastructure of the environment and propagation of effects of the alteration through at least one of the boundary conditions to the installation.
G06F 30/13 - Architectural design, e.g. computer-aided architectural design [CAAD] related to design of buildings, bridges, landscapes, production plants or roads
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
The present disclosure provides vehicle collision avoidance system (CAS) that includes a first CAS module for a robotic vehicle that includes an interface to a first network; a hard stop interface communicatively coupled to the robotic vehicle; one or more computer processors; one or more computer readable storage media; and program instructions stored on the one or more computer readable storage media for execution by at least one of the one or more computer processors, the stored program instructions including instructions to: determine a relative position of a second CAS module based on information from the first network; responsive to determining that the second CAS module is within a first distance from the first CAS module, issue an alert; and responsive to determining that the second CAS module is within a second distance from the first CAS module, transmit a hard stop signal to the robotic vehicle.
G05D 1/693 - Coordinated control of the position or course of two or more vehicles for avoiding collisions between vehicles
G05D 1/248 - Arrangements for determining position or orientation using signals provided by artificial sources external to the vehicle, e.g. navigation beacons generated by satellites, e.g. GPS
Bio-based surfactants have great opportunity for use in a variety of applications such as laundry detergents, industrial cleaners, adjuvants, and oil & gas. Surfactants in these applications can be nonionic, anionic, cationic, or amphoteric. Utilizing high oleic soybean oil as a platform chemical, a variety of surfactants and properties can be produced. While early work focused solely on surfactant use in laundry cleaning and fracking, recent work has expanded functional groups and application evaluations in hard surface cleaning.
Bio-based surfactants have great opportunity for use in a variety of applications such as laundry detergents, industrial cleaners, adjuvants, and oil & gas. Surfactants in these applications can be nonionic, anionic, cationic, or amphoteric. Utilizing high oleic soybean oil as a platform chemical, a variety of surfactants and properties can be produced. While early work focused solely on surfactant use in laundry cleaning and fracking, recent work has expanded functional groups and application evaluations in hard surface cleaning.
The current invention expands on Battelle's high oleic soybean oil (HOSO) surfactant technology. Use of HOSO overcomes the limitations of regular soybean oil and significantly reduces or eliminates undesirable byproducts in most chemistries. However, with use of select reagents, a few candidates were achievable with regular epoxidized soybean oil (ESO). The HOSO surfactant platform offers several key advantages including: a highly water miscible (not typical of C18 surfactants) and water stable surfactant; ability to adjust and vary hydrophilic-lipophilic (HLB) values for stain removal performance; and increased biodegradability without toxic or persistent by-products.
Disclosed herein are formulations comprising biologically prepared fibers and methods of preparing said formulations. These formulations can be utilized for repair of structures comprised of a variety of materials, including cementitious material, natural rock, mortar, and concrete. The formulation includes biologically prepared fibers, and a solvent or carrier solution. The formulation may additionally and optionally incorporate at least one enzyme. Once the formulation containing the biologically prepared fibers is applied to a void or crack within the structure, the fibers form a three-dimensional fibrous scaffold configuration in the void of the structure.
In one aspect, a screening tool for detecting whether a predetermined type of liquid is contained in a container includes a sensor arm subsystem in communication with a processing subsystem. The processing subsystem includes a processor disposed in a housing, an AC/DC converter electrically coupled to the processor, and ultrasonic components electrically coupled to the processor and the AC/DC converter. The sensor arm subsystem includes a sensor electrically coupled to the ultrasonic components, a temperature sensor electrically coupled to the processor, and an operator interface electrically couple to the processor.
G01N 29/22 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object Details
Polymer waste is converted to graphite and graphitic porous carbons with the aid of solid additives. The air processing developed in this invention overcomes the oxygen diffusion bottlenecks for processing bulk polymer waste, achieving char yield over three orders of magnitude compared to without using solid additives. Thermally stabilized materials can be converted into highly crystalline flake graphite via low-temperature catalytic graphitization with a very high degree of graphitization. The plastics-derived graphite showed excellent electrochemical performance as anode material for lithium-ion battery anodes, capacitors, and supercapacitors. Graphite compositions are described.
C08J 11/04 - Recovery or working-up of waste materials of polymers
C08J 11/12 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by dry-heat treatment only
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
24.
Upcycling Plastic Wastes into Graphites, Graphenes and Graphitic Carbons, for Electrochemical Energy Storage Devices
Polymer waste is converted to graphite and graphitic porous carbons with the aid of solid additives. The air processing developed in this invention overcomes the oxygen diffusion bottlenecks for processing bulk polymer waste, achieving char yield over three orders of magnitude compared to without using solid additives. Thermally stabilized materials can be converted into highly crystalline flake graphite via low-temperature catalytic graphitization with a very high degree of graphitization. The plastics-derived graphite showed excellent electrochemical performance as anode material for lithium-ion battery anodes, capacitors, and supercapacitors. Graphite compositions are described.
The present disclosure relates generally to systems, methods, and devices for interpreting neural signals to determine a desired movement of a target, transmitting electrical signals to the target, and dynamically monitoring subsequent neural signals or movement of the target to change the signal being delivered if necessary, so that the desired movement is achieved. In particular, the neural signals are decoded using a feature extractor, decoder(s) and a body state observer to determine the electrical signals that should be sent.
Nickel alloys, methods of making nickel alloys, articles including the nickel alloys, uses of the alloys, and methods of treating nickel alloys are described. The inventive heat resistant structural materials are suitable for applications requiring high yield stress at room temperature and good creep strength at high temperatures, such as in gas turbines, steam turbines, fossil energy boilers, aero engines, power generation systems using fluids such as supercritical carbon dioxide (e.g., advanced ultra-supercritical power plants), concentrated solar power plants, nuclear power plants, molten salt reactors: turbine blades, casings, valves, heat exchangers and recuperators.
C22C 19/05 - Alloys based on nickel or cobalt based on nickel with chromium
C22F 1/10 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of nickel or cobalt or alloys based thereon
27.
STABILIZED POROUS SILICON STRUCTURE FOR HIGHLY STABLE SILICON ANODE AND METHODS OF MAKING
Stabilized porous silicon particles are disclosed. The particles include a porous silicon particle comprising a plurality of interconnected silicon nanoparticles and (i) a heterogeneous layer comprising a discontinuous SiC coating that is discontinuous across a portion of pore surfaces and across a portion of an outer surface of the porous silicon particle, and a 10 continuous carbon coating that covers outer surfaces of the discontinuous SiC coating, and remaining portions of the pore surfaces and the outer surface of the porous silicon particle, or (ii) a continuous carbon coating on surfaces of the porous silicon particle, including the outer surface and pore surfaces. Methods of making the stabilized porous silicon particles also are disclosed.
This invention addresses the need for efficient dry skin electrodes. Robust, flexible Mixed Ionic Electronic Conductor (MIEC) electrodes were prepared by an aqueous solution route resulting in electrically conductive networks of carbon nanotubes (CNTs) and ionically conductive elastic matrix. The flexible electrode was characterized in terms of conductivity, ionic charge transfer resistance, and water uptake. The flexible electrode maintained low resistance even after multiple cycles of 50% extension and contraction.
C08J 5/02 - Direct processing of dispersions, e.g. latex, to articles
H01B 1/24 - Conductive material dispersed in non-conductive organic material the conductive material comprising carbon-silicon compounds, carbon, or silicon
29.
METHOD FOR TEXTILE AND POLYESTER DECONSTRUCTION AND UPCYCLING TO BIOPLASTIC IN A HALOPHILE
Methods for deconstructing polyester-cotton blended textile waste and biodegradable polyester packaging waste using microbial cells for the fermentative production of polyhydroxybutyrate (PHB), novel engineered Halomonas strains, and use of these strains in PHB production. An engineered microbial cell and compositions comprising PHB are also described.
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
30.
RADICAL SCAVENGERS, CATALYTIC STRUCTURES WITH RADICAL SCAVENGERS, AND METHODS FOR FABRICATION AND USE THEREOF
A catalytic structure can comprise a catalyst and one or more radical scavengers. Each radical scavenger can comprise one or more nanoparticles. Each nanoparticle can be formed as an oxide or oxynitride and can comprise at least one metal selected from titanium (Ti), zirconium (Zr), hafnium (Hf), rutherfordium (Rf), vanadium (V), niobium (Nb), tantalum (Ta), and dubnium (Db). In some embodiments, the radical scavenger can be used in an oxygen reduction reaction, for example, to decompose hydrogen peroxide into water and oxygen. In some embodiments, the catalytic structure with radical scavengers can exhibit enhanced durability, for example, when incorporated into a proton-exchange membrane (PEM) fuel cell.
A broadband RF imaging device includes a broadband RF aperture array, at least one RF receiver, and a computer. The at least one RF receiver has short RF connections with the broadband RF aperture array, e.g. length 10 meters or less. The computer has a digital data connection to the at least one RF receiver. Each RF receiver is configured to receive broadband RF signal data over a sampling time interval from the broadband RF aperture array, and to digitize the broadband RF signal data to generate digitized broadband RF signal data, and to store the digitized broadband RF signal data locally at the RF receiver. The computer receives the digitized broadband RF signal data stored locally at the at least one RF receiver, and is programmed to reconstruct an RF image from the digitized broadband RF signal data received from the at least one RF receiver.
G01S 13/02 - Systems using reflection of radio waves, e.g. primary radar systemsAnalogous systems
H04B 1/00 - Details of transmission systems, not covered by a single one of groups Details of transmission systems not characterised by the medium used for transmission
32.
CONCEPT AND METHOD FOR LARGE ION POPULATION SPACE CHARGE DRIVEN ION MOBILITY SEPARATIONS
Methods include introducing an ion quantity into an ion accumulation region, wherein the ion accumulation region includes an ion wall controllably blocking a movement of the ion quantity past the ion wall, wherein the ion wall is produced by one or more ion wall electrodes of an electrode arrangement, and directing the ion quantity in a direction towards the ion wall to increase a density of the ion quantity adjacent to the ion wall, such that the quantity of ions becomes space charge separated based on mobility along the direction and adjacent to the ion wall. Related apparatus provide space charge driven mobility separations.
Methods include introducing an ion quantity into an ion accumulation region, wherein the ion accumulation region, which can comprise a structure for lossless ion manipulations (SLIM) device allowing creation of a static or traveling wave electric field that moves ions towards an ion wall controllably blocking a movement of the ion quantity past the ion wall, wherein the ion wall is produced by one or more ion wall electrodes of an electrode arrangement, and directing the ion quantity in a direction towards the ion wall to increase a density of the ion quantity adjacent to the ion wall, such that the quantity of ions becomes space charge separated based on mobility along the direction and adjacent to the ion wall. Related apparatus provide space charge driven mobility separations.
Provided are Cry3Aa protein crystals comprising a negatively-charged biomolecule encapsulated therein. The solvent channel of the Cry3Aa protein crystal comprises one or more amino acid substitutions of an uncharged or negatively charged amino acid for a positively charged amino acid. Encapsulation of the biomolecule comprises interaction of the biomolecule with the one or more positively charged amino acids in the solvent channel. Negatively-charged biomolecules of interest include nucleic acids and negatively-charged proteins. In some instances, the negatively-charged biomolecule is an RNA (e.g., an siRNA) adapted to reduce expression of a target gene by RNA interference (RNAi). Methods of using the Cry3Aa protein crystals are also provided. For example, provided are methods of controlling a pest, a bacterium, a virus, a fungus, or a parasite using the Cry3Aa protein crystals. Methods of producing the Cry3Aa protein crystals are also provided.
A Friction Stir Welding (FSW) approach can be used to join two structures, such as a plate to a base structure, or two portions of a wall of a structure such as a tubular structure (e.g., a pipe or vessel). According to various examples, FSW can be used for forming welds on an exterior-facing portion of a structure (e.g., externally), or on an interior-facing portion of a structure, such as within a confined environment. As an example, FSW can be performed within the confined environment using a compact spindle configuration as shown and described herein. FSW generally refers to a solid-phase processing technique where a tool is applied to a work piece, with rotation of the tool relative to the workpiece along with application of a forging force to drive a face of the tool into the workpiece to frictionally induce plastic deformation of material.
B23K 20/12 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating the heat being generated by frictionFriction welding
In an integrated circuit (IC) assessment method, an artificial intelligence (AI) component comprising at least one artificial neural network (ANN) is trained to transform layout rendering tiles of a rendering of a reference IC into corresponding reference layout image tiles extracted from at least one layout image of the reference IC. Using the trained AI component, standard cell layout renderings of a library of GDSII or OASIS standard cell layout renderings are transformed into as-fabricated standard cell layout renderings forming a library of as fabricated standard cell layout renderings. Instantiated standard cells and their placements in the layout image of an IC-under-test are identified by matching the instantiated standard cells with corresponding as-fabricated standard cell layout renderings retrieved from the library of as fabricated standard cell layout renderings.
G06F 30/327 - Logic synthesisBehaviour synthesis, e.g. mapping logic, HDL to netlist, high-level language to RTL or netlist
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
G06F 30/3308 - Design verification, e.g. functional simulation or model checking using simulation
G06F 30/333 - Design for testability [DFT], e.g. scan chain or built-in self-test [BIST]
G06F 30/367 - Design verification, e.g. using simulation, simulation program with integrated circuit emphasis [SPICE], direct methods or relaxation methods
G06F 30/392 - Floor-planning or layout, e.g. partitioning or placement
G06F 30/398 - Design verification or optimisation, e.g. using design rule check [DRC], layout versus schematics [LVS] or finite element methods [FEM]
G06F 119/18 - Manufacturability analysis or optimisation for manufacturability
Provided are Cry3Aa protein crystals comprising a negatively-charged biomolecule encapsulated therein. The solvent channel of the Cry3Aa protein crystal comprises one or more amino acid substitutions of an uncharged or negatively charged amino acid for a positively charged amino acid. Encapsulation of the biomolecule comprises interaction of the biomolecule with the one or more positively charged amino acids in the solvent channel. Negatively-charged biomolecules of interest include nucleic acids and negatively-charged proteins. In some instances, the negatively-charged biomolecule is an RNA (e.g., an siRNA) adapted to reduce expression of a target gene by RNA interference (RNAi). Methods of using the Cry3Aa protein crystals are also provided. For example, provided are methods of controlling a pest, a bacterium, a virus, a fungus, or a parasite using the Cry3Aa protein crystals. Methods of producing the Cry3Aa protein crystals are also provided.
C07K 14/325 - Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
A61K 47/66 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
C07K 14/195 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria
C12N 11/02 - Enzymes or microbial cells immobilised on or in an organic carrier
C12N 15/75 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
38.
METHOD FOR ACTIVATING SOLID POLYMER ELECTROLYTE FOR USE IN SOLID-STATE POLYMER BATTERY
Disclosed herein is a method for activating a solid polymer electrolyte (SPE) to facilitate making and using a solid-state polymer battery that can be operated at room temperature. The activation method disclosed herein comprises exposing the SPE to activating conditions that facilitate converting the SPE into an activated SPE that exhibits improved properties relative to the SPE prior to activation. The activated SPE can be used in solid-state polymer batteries that exhibit improved performance at room temperature. The SPE can be activated separately from any battery in which it is used, or it can be activated after having been combined with components of the battery.
A method of designing a robust integrated circuit that is not vulnerable to optical fault injection comprises training a variational autoencoder to identify regions in a target integrated circuit that are vulnerable to optical fault injection and altering the design of the target integrated circuit by altering the design of the vulnerable regions so that the target integrated circuit is no longer vulnerable to optical fault injection, thereby forming the robust integrated circuit.
A Friction Stir Welding (FSW) approach can be used to join two structures, such as a plate to a base structure, or two portions of a wall of a structure such as a tubular structure (e.g., a pipe or vessel). According to various examples, FSW can be used for forming welds on an exterior-facing portion of a structure (e.g., externally), or on an interior-facing portion of a structure, such as within a confined environment. As an example, FSW can be performed within the confined environment using a compact spindle configuration as shown and described herein. FSW generally refers to a solid-phase processing technique where a tool is applied to a work piece, with rotation of the tool relative to the workpiece along with application of a forging force to drive a face of the tool into the workpiece to frictionally induce plastic deformation of material.
B23K 20/12 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating the heat being generated by frictionFriction welding
A beam steering system includes a reduced footprint antenna comprising a plurality of protruding structures and elements arranged in an array comprising first and second sets of direction elements, where each element is defined between opposing faces of two adjacent protruding structures and a position of each element is located at a distance from a common origin of the elements of the array; phase gradient determination circuitry to determine a first and second phase gradient for the direction elements, where the phase gradients are based on a first and a second angle of a target with respect to the reduced footprint antenna array, and an operating frequency of the reduced footprint antenna array; and phase shift determination circuitry to determine a first and second phase shift, for each of the elements, and to determine a resultant phase shift, for each element, by summing the respective first and second phase shifts.
H01Q 3/36 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the relative phase or relative amplitude of energisation between two or more active radiating elementsArrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the distribution of energy across a radiating aperture varying the phase by electrical means with variable phase-shifters
H01Q 3/44 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the electric or magnetic characteristics of reflecting, refracting, or diffracting devices associated with the radiating element
H01Q 1/36 - Structural form of radiating elements, e.g. cone, spiral, umbrella
H01Q 21/29 - Combinations of different interacting antenna units for giving a desired directional characteristic
H01Q 25/02 - Antennas or antenna systems providing at least two radiating patterns providing sum and difference patterns
H01Q 13/08 - Radiating ends of two-conductor microwave transmission lines, e.g. of coaxial lines, of microstrip lines
H01Q 9/28 - Conical, cylindrical, cage, strip, gauze or like elements having an extended radiating surface Elements comprising two conical surfaces having collinear axes and adjacent apices and fed by two-conductor transmission lines
42.
METHODS AND SYSTEM OF GRAPHITIC CARBON AND HYDROGEN PRODUCTION BY MICROWAVE PYROLYSIS OF NATURAL GAS, CHEMICAL TREATMENT AND ELECTROCHEMICAL CONVERSION
A system and method for producing graphitic carbon, with the method including generating amorphous carbon by microwave pyrolysis of a natural gas feedstock in the presence of a carbon catalyst; treating the amorphous carbon with an oxidizing agent to introduce oxygen functionalities; and converting the treated amorphous carbon to graphitic carbon through electrochemical methods.
The present disclosure is directed to compositions and methods that use the principles of DNA origami to package and archive data stored in multiple indexed DNA oligonucleotides. These structures allow for selective physical data access and retrieval from a molecular pool of DNA origami (DNAO) nanostructures comprising the data bearing oligonucleotides.
The present disclosure is directed to compositions and methods that use the principles of DNA origami to package and archive data stored in multiple indexed DNA oligonucleotides. These structures allow for selective physical data access and retrieval from a molecular pool of DNA origami (DNAO) nanostructures comprising the data bearing oligonucleotides.
The present invention provides for a method to increase production of isoprenol by a genetically modified Pseudomonas cell, the method comprising: (a) providing a genetically modified Pseudomonas cell comprising one or more of heterologous genes encoding: MvaE, AtoB, MvaS, MK, PMDHKQ, AphA, and PhoA; and (b) culturing or growing the genetically modified Pseudomonas cell in a medium to produce isoprenol; wherein (i) the genetically modified Pseudomonas cell is deleted, knocked out, or reduced in expression of one or more of the following endogenous genes: a gene at PP_2675 locus (or a deletion of the PP_2675 locus), phaABC, mvaB, hbdH, ldhA, gntZ, ppsA, pycAB, gltA, and aceA, and/or (ii) the medium comprises one or more amino acids that reduce the catabolism of isoprenol.
In an approach to non-destructive inspection of IC devices, one or more images of a Device Under Test (DUT) are received from one or more imaging devices. Observed features are detected in the one or more images and producing a first synthetic representation of a part design of the DUT that includes the observed features. The presence of one or more first unobserved features are inferred, where the one or more first unobserved features are inferred using a mapping and inference model (MIM). The one or more first unobserved features are added to the first synthetic representation of the part design of the DUT.
The invention relates to control compositions for sequencing and for chemical analyses, such as analytical chemistry analyses. More particularly, the invention relates to control compositions for sequencing and for chemical analyses having at least one barcode sequence fragment and at least one universal sequence fragment, and to methods of their use.
An energy storage system comprising a molten alkali metal in contact with a layer disposed on a surface of a substrate, wherein the surface layer comprises a composite comprising carbon, and the surface layer is metal-free and metal oxide-free.
A beam steering system includes a differentially segmented aperture antenna comprising a plurality of pyramid structures arranged in an array, and a plurality of elements formed in an array, each element being defined between two adjacent pyramid structures; phase conversion circuitry to determine a phase conversion for each element, the phase conversion for each element being based on an angle of a target with respect to the element, and an operating frequency of the DSA antenna; transmit phase shift circuitry to apply a phase difference for each element based on the phase conversion, the phase difference steering the signal to the target so that the signal interferes constructively; and receive phase shift circuitry to apply a phase difference for each element based on the phase conversion, causing the signal to interfere constructively for a signal of interest, and suppresses an unwanted signal by steering the signal into a null.
H01Q 3/36 - Arrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the relative phase or relative amplitude of energisation between two or more active radiating elementsArrangements for changing or varying the orientation or the shape of the directional pattern of the waves radiated from an antenna or antenna system varying the distribution of energy across a radiating aperture varying the phase by electrical means with variable phase-shifters
H01Q 21/06 - Arrays of individually energised antenna units similarly polarised and spaced apart
H01Q 21/29 - Combinations of different interacting antenna units for giving a desired directional characteristic
50.
CAUSAL RELATIONAL ARTIFICIAL INTELLIGENCE AND RISK FRAMEWORK FOR MANUFACTURING APPLICATIONS
In an approach to CRAI and risk framework for manufacturing applications, there is thus provided a computer-implemented method for causal effect prediction, the computer-implemented method including: identifying, by one or more computer processors, an intervention, wherein the intervention is selected from the group consisting of threats, failures, corrections, and relevant outputs; collecting, by the one or more computer processors, process dependency data; creating, by the one or more computer processors, an intervention model; combining, by the one or more computer processors, the process dependency data and the intervention model to create a combined process dependency graph; training, by the one or more computer processors, a causal relational artificial intelligence (CRAI) model; and determining, by the one or more computer processors, an estimate of an intervention efficacy.
G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
G06F 18/214 - Generating training patternsBootstrap methods, e.g. bagging or boosting
G06F 18/2323 - Non-hierarchical techniques based on graph theory, e.g. minimum spanning trees [MST] or graph cuts
51.
Mixed-matrix composite integrated fiber optic CO2 sensor
A mixed-matrix composite integrated fiber-optic (FO) sensor system was developed that reliably operates as a detector for gas-phase and dissolved CO2. A mixed-matrix composite sensor coating on the FO sensor comprising plasmonic nanocrystals and zeolite embedded in a polymer matrix. The mixed-matrix composite FO sensor showed excellent reversibility/stability in a high humidity environment and sensitivity to gas-phase CO2 over a large concentration range. The sensor exhibited the ability to sense CO2 in the presence of other geologically relevant gases. A prototype FO sensor configuration which possesses a robust sensing capability for monitoring dissolved CO2 in natural water was demonstrated. Reproducibility was confirmed over many cycles, both in a laboratory setting and in the field.
In an approach to enforcing policy without collateral damage using an agent sandbox, a system includes computer processors; non-transitory computer readable storage media; and program instructions to fork execution from a parent agent process into a child agent process; receive on the child agent process a target-specific object code of a capability; load on the child agent process a shared library using code inherited from a statically linked address space of the parent agent process; and interpose each standard C library wrapper function on the child agent process on a corresponding libc call. For each libc call, parse a message on the parent agent process to determine if the libc call is allowed by policy; responsive to determining that the libc call is allowed by policy, proceed with the execution; and responsive to determining that the libc call is not allowed by policy, terminate the child agent process.
G06F 21/53 - Monitoring users, programs or devices to maintain the integrity of platforms, e.g. of processors, firmware or operating systems during program execution, e.g. stack integrity, buffer overflow or preventing unwanted data erasure by executing in a restricted environment, e.g. sandbox or secure virtual machine
53.
METHODS OF CHEMICAL SEPARATION USING SELECTIVE AND SEQUENTIAL PRECIPITATION IN REACTION-DIFFUSION GEL MEDIA
A reaction-diffusion method for material separation using inexpensive and scalable gel medium (such as agarose or gelatin in a cylindrical tube) and a precipitating agent (such as sodium hydroxide, potassium hydroxide, or an oxalate). Basic embodiments place a solution containing dissolved ions containing one or more metals of interest in contact with a hydrogel that contains at least one precipitation agent. Diffusion and precipitation reactions occur over time to cause physical displacement or separation and thus cause enhanced concentration of different ions at different locations or depths within the hydrogel.
C22B 3/24 - Treatment or purification of solutions, e.g. obtained by leaching by physical processes, e.g. by filtration, by magnetic means by adsorption on solid substances, e.g. by extraction with solid resins
54.
OPTICAL END-POINT DETECTION FOR INTEGRATED CIRCUIT DELAYERING; SYSTEMS AND METHODS USING THE SAME
Systems for determining an end-point of a delayering process using optical end-point detection are described. In embodiments, the systems include a controller with an optical end-pointing (OE) module that is configured to determine an end-point of a delayering process based at least in part on the color or thickness of a surface layer of an integrated circuit (IC). In embodiments, the OE module determines whether an end-point of the delayering process has been reached based at least in part on a comparison of a determined thickness of an IC surface layer to a target thickness. The thickness of the surface layer may be determined by the OE module using a machine learning model, such as a convolutional neural network. Methods of identifying an end-point of a delayering process are also described.
A Register Transfer Level (RTL) representation is recovered from a netlist representing an integrated circuit (IC). The netlist is converted to a graph comprising nodes belonging to a set of node types and edges connecting the nodes. The set of node types includes an instance node type representing an electronic component and a wire node type representing signal transfer between components. The graph is converted to a standardized graph by replacing subgraphs of the graph with standardized subgraphs. An RTL representation of the standardized graph is generated by operations including building signal declarations in a hardware description language (HDL) from the wire nodes of the standardized graph and building signal assignments in the HDL from instance nodes of the standardized graph.
A multifunctional material may include a solid inorganic sorbent. The multifunctional material may include a metal catalyst component, wherein the solid inorganic sorbent and metal catalyst component are integrated into a single material.
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01J 20/04 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
C07C 1/12 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon from oxides of carbon from carbon dioxide with hydrogen
Implementations are described herein that include producing sorbents that include a polymeric material and a zero-valent metal. An amount of radioactive iodine can be captured using the sorbent to produce iodine-loaded sorbents. Additionally, the iodine-loaded sorbents can be encapsulated in one or more metallic materials.
B01D 53/82 - Solid phase processes with stationary reactants
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
In an approach to enforcing policy without collateral damage using an agent sandbox, a system includes computer processors; non-transitory computer readable storage media; and program instructions to fork execution from a parent agent process into a child agent process; receive on the child agent process a target-specific object code of a capability; load on the child agent process a shared library using code inherited from a statically linked address space of the parent agent process; and interpose each standard C library wrapper function on the child agent process on a corresponding libc call. For each libc call, parse a message on the parent agent process to determine if the libc call is allowed by policy; responsive to determining that the libc call is allowed by policy, proceed with the execution; and responsive to determining that the libc call is not allowed by policy, terminate the child agent process.
G06F 21/53 - Monitoring users, programs or devices to maintain the integrity of platforms, e.g. of processors, firmware or operating systems during program execution, e.g. stack integrity, buffer overflow or preventing unwanted data erasure by executing in a restricted environment, e.g. sandbox or secure virtual machine
Disclosed herein is a method for dissolving ion exchange membranes to provide dissolved polymers, particularly at low temperatures and/or pressures, that can be recast to regenerate ion exchange membranes exhibiting reduced defects compared to the initial ion exchange membrane. In some aspects of the disclosure, the polymer exchange membranes include a perfluorosulfonic acid polymer. In some aspects of the disclosure, the method involves dissolving the membranes in one or more aprotic solvents, particularly at temperatures below 80° C.
An edge heater comprised of a resistive heating sheet having an edge that is relatively hot because the edge is located close to a constriction in the electrical pathway through the resistive heating sheet. The resistive heating sheet can be made with carbon nanotubes (CNTs). Methods of heating objects using the edge heater and methods of making the edge heater are also described.
H05B 3/14 - Heating elements characterised by the composition or nature of the materials or by the arrangement of the conductor characterised by the composition or nature of the conductive material the material being non-metallic
H05B 3/34 - Heating elements having extended surface area substantially in a two-dimensional plane, e.g. plate-heater flexible, e.g. heating nets or webs
A composition may include an engineered synthetic carbonate comprising a structure, morphology, or combination thereof differing relative to a reference carbonate, wherein. A composition may include a thermal decomposition threshold of the engineered synthetic carbonate is in a range of from about 5% to about 30% less than the reference carbonate.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
42 - Scientific, technological and industrial services, research and design
Goods & Services
Carbon-based, electrically conductive, de-icing material layers and preparations for industrial and consumer product settings, such as commercial or retail applications on aircrafts, vehicles, electronics, medical devices, consumer goods and home products Coating compositions in the nature of paint for industrial applications Research and development in the field of nanotechnology, nanostructured materials for thermal regulation and conductivity applications, thermal engineering, and material sciences; scientific research consulting in the field of thermal management regulation, nanomaterials, and smart materials; product research and development of thermal management systems and thermal interface materials using nanotechnology; engineering services for optimizing thermal systems using nanotechnology in both industrial and retail or lifestyle consumer product settings, including electronics, textiles, aerospace, energy, medical devices, and consumer goods; non-downloadable simulation software for modeling heat transfer, heat behavior, and performance testing
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
42 - Scientific, technological and industrial services, research and design
Goods & Services
Carbon-based, electrically conductive, de-icing material layers and preparations for industrial and consumer product settings, such as commercial or retail applications on aircrafts, vehicles, electronics, medical devices, consumer goods and home products Coating compositions in the nature of paint for industrial applications Research and development in the field of nanotechnology, nanostructured materials for thermal regulation and conductivity applications, thermal engineering, and material sciences; scientific research consulting in the field of thermal management regulation, nanomaterials, and smart materials; product research and development of thermal management systems and thermal interface materials using nanotechnology; engineering services for optimizing thermal systems using nanotechnology in both industrial and retail or lifestyle consumer product settings, including electronics, textiles, aerospace, energy, medical devices, and consumer goods; non-downloadable simulation software for modeling heat transfer, heat behavior, and performance testing
65.
METHODS AND SYSTEMS FOR ENHANCING CARBONATE-OXIDE THERMAL CYCLING EFFICIENCY FOR CO2 DIRECT AIR CAPTURE
A composition may include an engineered synthetic carbonate comprising a structure, morphology, or combination thereof differing relative to a reference carbonate, wherein. A composition may include a thermal decomposition threshold of the engineered synthetic carbonate is in a range of from about 5% to about 30% less than the reference carbonate.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
A modular radio frequency (RF) device includes N base units, each including a differential segmented array (DSA) tile with a support board and a two-dimensional (2D) array of electrically conductive tapered projections disposed on the support board. Neighboring pairs of the electrically conductive tapered projections form RF pixels. The N DSA tiles are arranged to form an RF aperture. The N base units are programmed to switch the RF aperture between a first operating mode and a second operating mode. In the first operating mode, the N base units are operated as at least two independent subsets with each subset operating as an RF transmitter or receiver independently of the other subsets. In the second operating mode all N base units coherently combine as a single phased array RF transmitter or receiver.
Disclosed herein is an electrochemical characterization apparatus and system that facilitates high-throughput measurements of various different properties and/or performance characteristics of components of an energy storage and conversion device, such as an electrolyte and/or electrodes. Also disclosed are methods for using the electrochemical characterization apparatus and system.
Disclosed herein are systems, devices and methods for detection, identification and sorting of cells and/or cellular-associated targets. The system comprises at least a microfluidic device and a Raman detection and identification unit. The microfluidic device comprises a junction structure aligned with the Raman detection and identification unit, wherein a cell confined at the junction structure is detected and analyzed by the Raman detection and identification unit and routed into a collection channel based on analysis of Raman spectra.
A method implemented by a software for a multimodal evaluation engine stored on a memory is provided herein. The software is executable by a processor coupled to the memory to cause the method. The method includes receiving multimodal signatures of an object of interest from inspection elements and processing the multimodal signatures to transform the multimodal signatures into formats. The method also includes generating data representations of the formats and detecting whether anomalies are present within the object of interest based on the data representations.
Disclosed herein are systems, devices and methods for detection, identification and sorting of cells and/or cellular-associated targets. The system comprises at least a microfluidic device and a Raman detection and identification unit. The microfluidic device comprises a junction structure aligned with the Raman detection and identification unit, wherein a cell confined at the junction structure is detected and analyzed by the Raman detection and identification unit and routed into a collection channel based on analysis of Raman spectra.
Implementations are described herein that relate to manufacturing articles comprised of one or more metallic materials. In one or more examples, the one or more metallic materials can have a preformed shape that is inserted into the die. In one or more additional examples, the one or more metallic materials can include one or more powders or flakes disposed in the die. The material is then contacted within the die by a tool that moves in a rotational direction and in a vertical direction. The manufactured articles can have a shape that corresponds to the shape of the die.
The disclosure relates to block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for encapsulation and for delivery of large nucleic acids.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
75.
METAL-CONTAINING PEPTOID MEMBRANES FOR HYDROLYSIS OF ORGANOPHOSPHATES
Membranes, articles, and methods for hydrolysis of compounds comprising ester or phosphate ester groups are disclosed. The membranes and articles comprise a plurality of peptoids, at least one peptoid of the plurality of peptoids has a hydrophobic unit, a hydrophilic unit, and a metal-coordination ligand. The metal-coordination ligands are configured to bind to one or more metal ions. The metal-containing peptoid membranes self-assemble and show high efficiency for catalytic organophosphate hydrolysis.
A method and system for the destruction of PFAS compounds using reactive metal oxides is disclosed herein. The method includes introducing a metal oxide into a vessel, where the vessel is heated to a temperature in a range of approximately 300°C to approximately 700°C. The method also includes introducing a contaminated stream to the vessel, where the contaminated stream includes one or more PFAS compound. The method also includes reacting the contaminated stream with the metal oxide. The method also includes, resultant to the reacting, producing a solid non-toxic product.
In an approach to real-time sensor visualization in a presence of scattering particles, a system includes a vehicle, the vehicle comprising: one or more computing devices, Light Detection and Ranging (LiDAR) circuitry; and one or more vehicle sensors. The system is configured to: emit pulsed light waves from the LiDAR circuitry; receive return data from the LiDAR circuitry; receive sensor data from the one or more vehicle sensors; filter the return data and the sensor data to visualize a plurality of terrain points without obscuring points; and create a software rendered presentation of a surroundings.
A system for the payload delivery utilizing a machine vision model, the system including a camera-equipped component configured to capture images of a target array for pose calculations. The payload delivery system also includes at least one adaptive thresholding and neural network algorithm configured to recognize patterns of LEDs on the target array, and calculate navigation parameters based on the recognized patterns. The payload delivery system also includes a plurality of compensation mechanisms configured to accommodate errors induced by coupling of autonomous underwater vehicle platforms.
A01N 35/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio-analogues thereofDerivatives thereof, e.g. acetals
A01N 37/02 - Saturated carboxylic acids or thio-analogues thereofDerivatives thereof
A01N 37/06 - Unsaturated carboxylic acids or thio-analogues thereofDerivatives thereof
A01N 43/08 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom five-membered rings with oxygen as the ring hetero atom
The present disclosure relates to laboratory equipment including a laboratory needle for automated fluid delivery, a laboratory mixing vessel, a reduced friction laboratory powder dispenser, a laboratory vial, and a fluid-enabled and/or vacuum-enabled powder dispenser.
B01F 23/64 - Mixing solids with solids using rotatable mixing elements at the lower end of discharge hoppers
B01F 27/053 - Stirrers characterised by their elements, materials or mechanical properties characterised by their materials
B01F 27/072 - Stirrers characterised by their mounting on the shaft characterised by the disposition of the stirrers with respect to the rotating axis
B01F 27/192 - Stirrers with two or more mixing elements mounted in sequence on the same axis with dissimilar elements
B01F 27/806 - Mixers with rotary stirring devices in fixed receptaclesKneaders with stirrers rotating about a substantially vertical axis wherein the stirrers or the receptacles are moved in order to bring them into operative positionMeans for fixing the receptacle with vertical displacement of the stirrer, e.g. in combination with means for pivoting the stirrer about a vertical axis in order to co-operate with different receptacles
in vivoin vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for encapsulation and for delivery of large nucleic acids.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
In an approach to real-time sensor visualization in a presence of scattering particles, a system includes a vehicle, the vehicle comprising: one or more computing devices, Light Detection and Ranging (LiDAR) circuitry; and one or more vehicle sensors. The system is configured to: emit pulsed light waves from the LiDAR circuitry; receive return data from the LiDAR circuitry; receive sensor data from the one or more vehicle sensors; filter the return data and the sensor data to visualize a plurality of terrain points without obscuring points; and create a software rendered presentation of a surroundings.
The present disclosure provides regenerative sorbent membranes and membrane assemblies for direct air capture (DAC) systems for CO2 capture, wherein the sorbent membranes have a conductive film disposed thereon. The conductive film provides a means for direct heating of the sorbent membrane to desorb captured CO2 and regenerate the membrane. The conductive films are comprised of carbon nanotubes (CNTs) and a polymeric binder. Methods of making a regenerative sorbent membrane for direct air capture systems are also disclosed.
B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
The disclosure relates to block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for delivering nucleotides that encode polypeptides.
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
C08F 299/02 - Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers from unsaturated polycondensates
85.
POLYMER NANOPARTICLE COMPOSITIONS FOR NON-VIRAL GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM
The disclosure relates to block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for delivering nucleotides to the central nervous system.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
86.
METHODS FOR PRODUCTION OF MICROALGINATE BEADS AND USES FOR ENCAPSULATION
The invention relates to scale-up of alginate microbeads encapsulating biological actives comprising proteins and microorganisms. The invention provides a system and method for reliably producing micrometer size range alginate beads, in large volumes, to advance and sustain agriculture. Using any desired microorganism, the system and method provides a successful encapsulation approach, retaining the viability of the microorganism.
in vivoin vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for delivering nucleotides that encode polypeptides.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
88.
POLYMER NANOPARTICLE COMPOSITIONS FOR NON-VIRAL GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM
in vivoin vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for delivering nucleotides to the central nervous system.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
222 and regenerate the membrane. The conductive films are comprised of carbon nanotubes (CNTs) and a polymeric binder. Methods of making a regenerative sorbent membrane for direct air capture systems are also disclosed.
B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
90.
SYSTEMS AND METHODS FOR UTILIZING FOAM FRACTIONATION FOR CONTAMINATE DESTRUCTION
A system for the destruction of PFAS compounds through mineralization with reactive oxides is disclosed herein. The system includes an acquisition unit for obtaining reactive oxides. The system also includes a mixing unit operatively connected to the acquisition unit, where the mixing unit is configured to combine PFAS-contaminated waste with the reactive oxides. The system also includes a high-temperature treatment unit operatively connected to the mixing unit to subject the mixture of PFAS-contaminated waste and reactive oxides to a chemical reaction. The system includes a cooling unit operatively connected to the high-temperature treatment unit. The system includes a waste collection receptacle connected to the cooling unit. The system includes particulate vapor treatment systems, where PFAS-contaminated atmospheres from the high-temperature treatment unit and the cooling unit are captured to prevent emissions to the environment.
In an approach to three-dimensional object image projection and image augmentation, a system includes one or more computer processors; one or more graphics processing units; one or more computer readable storage media; and program instructions stored on the one or more computer readable storage media for execution by at least one of the one or more computer processors or at least one of the one or more graphics processing units. The stored program instructions include instructions to: retrieve an object image; retrieve a background image; determine one or more voids in the background image suitable for inserting the object image; manipulate the object image to fit into the background image; insert the object image into the background image to create a projected image; and perform the image augmentation on the projected image to produce a realistic synthetic image.
Membranes, articles, and methods for hydrolysis of compounds comprising ester or phosphate ester groups are disclosed. The membranes and articles comprise a plurality of peptoids, at least one peptoid of the plurality of peptoids has a hydrophobic unit, a hydrophilic unit, and a metal-coordination ligand. The metal-coordination ligands are configured to bind to one or more metal ions. The metal-containing peptoid membranes self-assemble and show high efficiency for catalytic organophosphate hydrolysis.
B01J 31/12 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing organo-metallic compounds or metal hydrides
A system to track personnel includes an antenna array associated with a first node to communicate with a second node; and processor circuitry. The processor circuitry to: determine a plurality of positions of the second node; determine a distance between the first node and the second node; determine a bearing between the first node and at least one of the positions; and determine a direction for the first node based on the bearing.
G01S 5/02 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using radio waves
G01S 5/00 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations
G01S 11/02 - Systems for determining distance or velocity not using reflection or reradiation using radio waves
G01S 11/04 - Systems for determining distance or velocity not using reflection or reradiation using radio waves using angle measurements
94.
METHODS FOR CREATING LINKAGE OF MULTIPLE VIRAL VECTORS FOR INTRACELLULAR DELIVERY
Methods and structures are disclosed for creating a physical linkage between two or more viral particles, which can covalently link the viral particles together. The methods and structures described herein are designed for purposes of improving efficiency and effectiveness of vector delivery into cells and tissues for purposes of gene therapy. Methods for linking two or more viral vectors comprise functionalizing a first vector with a first surface moiety and functionalizing a second vector with a second surface moiety. Thereafter, the first functionalized vector and second functionalized vector are combined so that the two surface moieties can react. During this reaction, the first surface moiety and the second surface moiety form a covalent linkage, thereby resulting in the physical linkage of both vectors to each other.
Methods and structures are disclosed for creating a physical linkage between two or more viral particles, which can covalently link the viral particles together. The methods and structures described herein are designed for purposes of improving efficiency and effectiveness of vector delivery into cells and tissues for purposes of gene therapy. Methods for linking two or more viral vectors comprise functionalizing a first vector with a first surface moiety and functionalizing a second vector with a second surface moiety. Thereafter, the first functionalized vector and second functionalized vector are combined so that the two surface moieties can react. During this reaction, the first surface moiety and the second surface moiety form a covalent linkage, thereby resulting in the physical linkage of both vectors to each other.
Disclosed herein are aspects of a system for coupling electrochemical marine carbon capture with photosynthesis. In some aspects of the present disclosure, the system comprises an electrochemical cell that converts saline water into (i) a base stream, (ii) an at least partially deionized water stream, and (iii) an acid stream. In some aspects, the system further comprises a biomass cultivation unit in fluid communication with the acid stream, the biomass cultivation unit comprising a photosynthetic organism. The acid stream catalyzes release of CO2 in a growth medium for the photosynthetic organism to accelerate growth of the photosynthetic organism relative to growth without the acid stream and facilitates CO2 storage by the photosynthetic organism. Also disclosed herein are aspects of a method for coupling electrochemical marine carbon capture with photosynthesis.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
The invention relates to scale-up of alginate microbeads encapsulating biological actives comprising proteins and microorganisms. The invention provides a system and method for reliably producing micrometer size range alginate beads, in large volumes, to advance and sustain agriculture. Using any desired microorganism, the system and method provides a successful encapsulation approach, retaining the viability of the microorganism.
A hydrophone flow shield and hydrophone assembly including a hollow polyurethane flow shield with one or more features for improving reliable operation and assembly wherein the features include a recess for holding a clamp for securing the shield to the hydrophone, a slot or through hole extending longitudinally in the clamping region but not extending toward a closed end of the shield beyond the clamping region and when sizing of the shield and hydrophone are not closely matched providing for indirect sealing via a gasket that is located between the shield and the hydrophone.
A mobile robot may include one or more driven wheels, one or more sensors, and a sample collector. The sample collector may include a collection medium holder, a plurality of collection mediums disposed within the collection medium holder, and a collection medium applicator configured to releasably couple to a respective collection medium disposed within the collection medium holder.
A shear-assisted extrusion process and related apparatus can include establishing shear-assisted extrusion to form a first extrudate, suspending such extrusion, and re-starting extrusion with the same material or initiating extrusion of a different material or different billet of the same material to form a second extrudate, without requiring disassembly of extrusion apparatus or clearing of an extrusion die tool. A resulting combined extrudate can include a fused region joining the first extrudate and the second extrudate. Such processing does not require (nor generally involve) melting of feedstock materials and can be performed even if cooling occurs of the die tool and associated billet material between suspension of extrusion and re-start or initiation of subsequent extrusion. In this manner, downtime can be reduced or minimized, or extrusions can be formed having different material properties along their axial extent, as illustrative examples.