The present invention relates to a three-dimensional adhesive device to be attached to the body surface of a mammal comprising a microelectronic sensing system characterized by (a) a three-dimensional adhesive body made of a pressure sensitive adhesive having an upper surface and a bottom surface; (b) a microelectronic system embedded in the body of the pressure sensitive adhesive; (c) one or more cover layer(s) attached to the upper surface; and (d) optionally a release liner releasable attached to the bottom surface of the adhesive device. Suitably the microelectronic system is a microelectronic sensing system capable of sensing physical input such as pressure, vibration, sound, electrical activity (e.g. from muscle activity), tension, blood-flow, moisture, temperature, enzyme activity, bacteria, pH, blood sugar, conductivity, resistance, capacitance, inductance or other chemical, biochemical, biological, mechanical or electrical properties.
The invention provides a monitoring device (1) for attachment to a surface of a subject. The device comprises a data collector (2) and a processor (3) as two separate parts which can be detachably joined such that physiological signals which are detected by the data collector can be transferred to the processor for signal processing and provision of monitoring data. At least one of the data collector and the processor comprises a transducer which can convert the physiological signal to a data signal which can be processed electronically. The data collector is adapted for adhesive contact with a skin surface, and may comprise an adapter (6) for the detachable attachment of the processor.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
F16B 2/20 - Clips, i.e. with gripping action effected solely by the inherent resistance to deformation of the material of the fastening
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
Systems, devices, methods, and techniques relating to generating and presenting information related to heart rate data. In one aspect, a system includes a monitoring device configured to obtain physiological data for a living being and to generate annotation data based on the physiological data for a total time period, a processing system configured to obtain the annotation data via a communication channel from the monitoring device and to generate for display based on the annotation data a daily patient report that includes, a chart showing summary statistical data for a proportion of a total monitored time period spent in cardiac arrhythmia for each of a plurality of days and summary statistical data for a proportion of the total monitored time period not spent in cardiac arrhythmia for each of the plurality of days.
A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.
A system for reporting cardiologic data includes a patient-portable monitoring device and circuitry. The monitoring device is configured to detect electrocardiogram (ECG) data and patient-initiated event data. The circuitry is configured to receive the ECG data and the patient-initiated event data; detect atrial fibrillation (AF) events in the ECG data; calculate the duration of each AF event by subtracting the respective start time from the respective stop time of each AF event; compare the duration of each AF event to a first duration threshold; store each AF event having a duration exceeding the first duration threshold; calculate a monitoring time period duration by subtracting the monitoring start time from the monitoring stop time; calculate, based on the stored AF events, AF burden; and output a graphical presentation of the patient-initiated event data, AF burden, and stored AF events. The first duration threshold is less than 30 seconds.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
6.
PREDICTING ATRIAL FIBRILLATION OR STROKE USING P-WAVE ANALYSIS
A system for predicting atrial fibrillation or stroke includes processing circuitry configured to receive ECG data from an ECG monitoring device, detect a first candidate P-wave represented in the ECG data, calculate a quality score of the first candidate P-wave by calculating a quality score of ECG data between the onset and the offset of the first candidate P-wave, detect a second candidate P-wave represented in the ECG data, calculate a quality score of the second candidate P-wave, compare the quality score of the first candidate P-wave with the quality score of the second candidate P-wave, store the candidate P-wave having the higher quality score, and calculate a characteristic of the stored P-wave, wherein the characteristic is at least one of a rate of rise of the stored P-wave, an area under the curve of the stored P-wave, and a duration of the stored P-wave.
Wireless sensors for medical and physiological use to be worn by a human to gather human biometric data; micro-electronic sensing systems, namely, sensors for medical and physiological use to be worn by a human to gather human biometric data
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Heart monitoring kits comprised primarily of adhesive plasters for medical use and also including wireless sensors for medical and physiological use to be worn by a human to gather human biometric data and micro-electronic sensing systems, namely, sensors for medical and physiological use to be worn by a human to gather human biometric data, but not including drug delivery patches
9.
End of service summary report for mobile cardiac outpatient telemetry
A method for filtering ECG data includes receiving ECG data of a patient, generating an ECG report comprising a plurality of pages, and presenting priority information on a first page of the plurality of pages. The priority information includes information identifying the patient, monitoring summary information including an indication of a total duration of a monitoring period, heart rate summary information including an average heart rate, a fastest heart rate, and a slowest heart rate, representative arrhythmia summary information including a count of ECG strips containing each of a plurality of types of cardiac arrhythmia, and atrial fibrillation summary information including an indication of atrial fibrillation burden during the monitoring period. The first page of the report does not include an ECG strip.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
A61B 5/316 - Modalities, i.e. specific diagnostic methods
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
A61B 5/0245 - Measuring pulse rate or heart rate using sensing means generating electric signals
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
10.
END OF SERVICE SUMMARY REPORT FOR MOBILE CARDIAC OUTPATIENT TELEMETRY
A method for filtering ECG data includes receiving ECG data of a patient, generating an ECG report comprising a plurality of pages, and presenting priority information on a first page of the plurality of pages. The priority information includes information identifying the patient, monitoring summary information including an indication of a total duration of a monitoring period, heart rate summary information including an average heart rate, a fastest heart rate, and a slowest heart rate, representative arrhythmia summary information including a count of ECG strips containing each of a plurality of types of cardiac arrhythmia, and atrial fibrillation summary information including an indication of atrial fibrillation burden during the monitoring period. The first page of the report does not include an ECG strip.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
11.
Ambulatory and centralized processing of a physiological signal
A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.
A method, a computer readable media and a hand-held device, the hand-held device may include a first sensor that is positioned such as to be contacted by a first hand of a user when the user holds the hand-held device; a second sensor that is positioned such as to be contacted by a second hand of the user when the user holds the hand-held device; wherein at least one sensor of the first sensor and the second sensor is a hybrid sensor that comprises an electrode, an illumination element and a light detector; and a health monitoring module arranged to process detections signals from the electrode and from the light detector such as to provide processed signals that are indicative of a state of the user.
A61B 5/0245 - Measuring pulse rate or heart rate using sensing means generating electric signals
A61B 5/0452 - Detecting specific parameters of the electrocardiograph cycle
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
13.
Monitoring device for attachment to a surface of a subject
The invention provides a monitoring device (1) for attachment to a stance of a subject. The device comprises a data collector (2) and a processor (3) as two separate parts which can be detachably joined such that physiological signals which are detected by the data collector can be transferred to the processor for signal processing and provision of monitoring data. At least one of the data collector and the processor comprises a transducer which can convert the physiological signal to a data signal which can be processed electronically. The data collector is adapted for adhesive contact with a skin surface, and may comprise an adapter (6) for the detachable attachment of the processor.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
F16B 2/20 - Clips, i.e. with gripping action effected solely by the inherent resistance to deformation of the material of the fastening
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A physiological data collection device obtains physiological data from a subject interface on a subject. The physiological data collection device includes a data connector such as a USB connector for connecting directly to a computer. When the physiological data collection device is connected to the computer, the physiological data is uploaded to a remote data processing center for computer-based analysis and review by a medical professional. A report can be provided to the subject based on the analysis and review. When the subject interface is physically connected to the physiological data collection device, the data connector is prevented from being connected to an external device such as the computer.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G06F 3/06 - Digital input from, or digital output to, record carriers
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 10/65 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records stored on portable record carriers, e.g. on smartcards, RFID tags or CD
15.
System and method for electro-cardiogram (ECG) medical data collection wherein physiological data collected and stored may be uploaded to a remote service center
A data collection unit obtains physiological data from a subject interface on a subject. The subject interface can be connected to the data collection unit. When the subject interface is connected to the data collection unit, subject interface contacts on the subject interface make contact with data collection unit contacts on the data collection unit. Some of the data collection unit contacts are for communicating physiological data from the subject interface to the data collection unit. Some of the contacts are for powering the data collection unit upon the subject interface being connected to the data collection unit and for powering down the data collection unit upon the subject interface being disconnected from the data collection unit.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
16.
System and method for electro-cardiogram (ECG) medical data collection wherein physiological data collected and stored may be uploaded to a remote service center
A data collection unit obtains physiological data from a subject interface on a subject. The subject interface can be connected to the data collection unit. When the subject interface is connected to the data collection unit, subject interface contacts on the subject interface make contact with data collection unit contacts on the data collection unit. Some of the data collection unit contacts are for communicating physiological data from the subject interface to the data collection unit. Some of the contacts are for powering the data collection unit upon the subject interface being connected to the data collection unit and for powering down the data collection unit upon the subject interface being disconnected from the data collection unit.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A monitoring device suitable for attachment to a surface of a subject, the device having a data collector and a processor. The data collector includes a flexible foil attached to a less flexible socket, where the foil forms a dermal side surface of the data collector for adhesion to a skin surface of a subject to be monitored. To enable communication of electrical signals between the data collector and the processor, the data collector includes a distribution structure formed as a pattern of an electrically conductive material on an outer surface of a foldable sheet. The foldable sheet forms a layer in the flexible foil and having an interface portion which is folded into an aperture in the socket to form a coupling inside the cavity for electrical communication with a matching coupling of the processor when the processor is received in the cavity.
A data acquisition system includes a receptacle and a data acquisition device. The receptacle has a housing, sensor inputs to receive data signals from sensors coupled to an object, and a rib to block insertion of a standard Universal Serial Bus (USB) plug and facilitate insertion of a modified USB plug having a slot that mates with the rib. The data acquisition device includes circuitry to receive, store and process data, a USB plug having pins operatively coupled to the circuitry, a first subset of pins configured to receive data signals from the receptacle and a second subset of pins configured to support standard USB communication with USB-compliant devices, and a slot formed in the USB plug such that the slot facilitates interconnection of the USB plug both with standard USB-compliant devices and with the receptacle, the slot mating with the rib to facilitate interconnection.
G06F 3/06 - Digital input from, or digital output to, record carriers
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
09 - Scientific and electric apparatus and instruments
Goods & Services
Computer software for monitoring and measuring patient reported symptoms, heart rate, blood pressure, body temperature, pain, the oxygen saturation of the blood, and other vital signs and diagnostic parameters from portable electronic patient monitors and patient sensors.
A data acquisition system includes a receptacle and a data acquisition device. The receptacle has a housing, sensor inputs to receive data signals from sensors coupled to an object, and a rib to block insertion of a standard Universal Serial Bus (USB) plug and facilitate insertion of a modified USB plug having a slot that mates with the rib. The data acquisition device includes circuitry to receive, store and process data, a USB plug having pins operatively coupled to the circuitry, a first subset of pins configured to receive data signals from the receptacle and a second subset of pins configured to support standard USB communication with USB-compliant devices, and a slot formed in the USB plug such that the slot facilitates interconnection of the USB plug both with standard USB-compliant devices and with the receptacle, the slot mating with the rib to facilitate interconnection.
H01R 13/642 - Means for preventing, inhibiting or avoiding incorrect coupling by position or shape of contact members
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G06F 3/06 - Digital input from, or digital output to, record carriers
H01R 27/00 - Coupling parts adapted for co-operation with two or more dissimilar counterparts
A data acquisition system includes a receptacle and a data acquisition device. The receptacle has a housing, sensor inputs to receive data signals from sensors coupled to an object, and a rib to block insertion of a standard Universal Serial Bus (USB) plug and facilitate insertion of a modified USB plug having a slot that mates with the rib. The data acquisition device includes circuitry to receive, store and process data, a USB plug having pins operatively coupled to the circuitry, a first subset of pins configured to receive data signals from the receptacle and a second subset of pins configured to support standard USB communication with USB-compliant devices, and a slot formed in the USB plug such that the slot facilitates interconnection of the USB plug both with standard USB-compliant devices and with the receptacle, the slot mating with the rib to facilitate interconnection.
G06F 3/00 - Input arrangements for transferring data to be processed into a form capable of being handled by the computerOutput arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
Systems and techniques are disclosed for determining the onset and offset of a ventricular fibrillation event and for distinguishing ventricular fibrillation from noise. In some examples, an electrocardiogram (ECG) signal is obtained; a transform is applied to the ECG signal to obtain an analytical pair, the analytical pair including the ECG signal and the transformed ECG signal; a speed-amplitude is determined from the analytical pair; and an onset of a ventricular fibrillation event is identified based at least one of a value of a cost function of the speed-amplitude over a window and a quantity of occurrences the speed-amplitude crosses a threshold over the window.
The invention provides a monitoring device (1) for attachment to a surface of a subject. The device comprises a data collector (2) and a processor (3) as two separate parts which can be detachably joined such that physiological signals which are detected by the data collector can be transferred to the processor for signal processing and provision of monitoring data. At least one of the data collector and the processor comprises a transducer which can convert the physiological signal to a data signal which can be processed electronically. The data collector is adapted for adhesive contact with a skin surface, and may comprise an adapter (6) for the detachable attachment of the processor.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
F16B 2/20 - Clips, i.e. with gripping action effected solely by the inherent resistance to deformation of the material of the fastening
A physiological data collection device obtains physiological data from a subject interface on a subject. The physiological data collection device includes a data connector such as a USB connector for connecting directly to a computer. When the physiological data collection device is connected to the computer, the physiological data is uploaded to a remote data processing center for computer-based analysis and review by a medical professional. A report can be provided to the subject based on the analysis and review. When the subject interface is physically connected to the physiological data collection device, the data connector is prevented from being connected to an external device such as the computer.
System and method for electro-cardiogram (ECG) medical data collection wherein physiological data collected and stored may be uploaded to a remote service center
A data collection unit obtains physiological data from a subject interface on a subject. The subject interface can be connected to the data collection unit. When the subject interface is connected to the data collection unit, subject interface contacts on the subject interface make contact with data collection unit contacts on the data collection unit. Some of the data collection unit contacts are for communicating physiological data from the subject interface to the data collection unit. Some of the contacts are for powering the data collection unit upon the subject interface being connected to the data collection unit and for powering down the data collection unit upon the subject interface being disconnected from the data collection unit.
A system and method for presenting information relating to heart data can involve operations including identifying arrhythmia events in physiological data obtained for a living being, receiving human assessments of at least a portion of the arrhythmia events, determining a measure of correlation between the human assessments and the identified events, and selectively presenting information regarding the identified events based on the measure of correlation. The operations can also include identifying atrial fibrillation events in physiological data obtained for a living being, obtaining heart rate data for the living being, and presenting information regarding the heart rate data and duration of the atrial fibrillation events together with a common time scale to pictographically represent heart rate trend with atrial fibrillation burden during a defined time period.
Systems, devices, methods, and techniques relating to generating and presenting information related to heart rate data. In one aspect, a system includes a monitoring device configured to obtain physiological data for a living being and to generate annotation data based on the physiological data for a total time period, a processing system configured to obtain the annotation data via a communication channel from the monitoring device and to generate for display based on the annotation data a daily patient report that includes, a chart showing summary statistical data for a proportion of a total monitored time period spent in cardiac arrhythmia for each of a plurality of days and summary statistical data for a proportion of the total monitored time period not spent in cardiac arrhythmia for each of the plurality of days.
A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.
Systems, devices, methods, and techniques relating to the identification of fiducial points. In one aspect, a machine implemented method includes obtaining a first time varying physiological signal and a second time varying physiological signal that relate to biological activity of an organism, the first time varying physiological signal and the second time varying physiological signal forming an analytic pair wherein the analytic pair has a time varying phase angle, defining a reference line by a lower boundary of a representation of the time varying phase angle with respect to a time period, and identifying a fiducial point based on the reference line.
Systems, methods, apparatus, and computer program products for detecting the existence of a sleep disorder in an individual using heart activity. In one aspect, machine-implemented methods include the actions of analyzing a machine-readable heart rate series of a monitored individual in the time domain using one or more digital data processing devices, detecting a cyclic variation in heart rate in the heart rate series as a result of the analysis in the time domain, and outputting, over an output, a report characterizing a sleep disorder event based on the detection of the cyclic variation in heart rate in the heart rate series. The cyclic variation in heart rate is indicative of a sleep disorder.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Adhesive plasters for medical use for use together with wireless sensors for medical and physiological use and micro-electronic sensing systems for medical and physiological use; but not including drug delivery patches. Wireless sensors for medical and physiological use, microelectronic sensing systems for medical and physiological use.
33.
Automated analysis of a cardiac signal based on dynamical characteristics of the cardiac signal
Systems and techniques relating to locating cardiac wave forms in a cardiac signal, and to detecting a physiological condition, such as ventricular fibrillation. In general, in one aspect, a machine-implemented method includes obtaining a sensed cardiac signal of an organism, the sensed cardiac signal comprising a time series x(t); applying a Hilbert (H) transform to the time series x(t) to obtain H(x(t)), wherein x(t) and H(x(t)) together forming a partial state space trajectory; determining a speed of trajectory, for the sensed cardiac signal, from the partial state space trajectory; and identifying physiological information concerning the organism based on a combination of first and second signal elements, the first signal element including a phase property or an amplitude property of the speed of trajectory, and the second signal element including an amplitude property of the partial state space trajectory.
A device includes a patient-portable remote monitoring unit to monitor one or more physiological characteristics of an individual and convey information characterizing the one or more physiological characteristics to a remote station. The monitoring unit includes a transmitter system capable to employ a selected one of three or more different communications channels to convey the information to the remote station, and a selection unit to select from among the three or more different communications channels for conveying the information to the remote station.
Systems and techniques for monitoring cardiac activity. In one aspect, a method includes collecting information describing the variability in heart rate over a series of beats, designating variability at a lower end of physiological values as being largely irrelevant to atrial fibrillation, designating variability in a midrange of physiological values as being indicative of atrial fibrillation, designating variability in an upper range of physiological values as being negatively indicative of atrial fibrillation, and determining a relevance of the variability described in the collection to atrial fibrillation.
Systems and techniques relating to monitoring physiological activity using partial state space reconstruction. In general, in one aspect, a partial state space is produced using an orthogonal, frequency-independent transform, such as Hilbert transform. The partial state space can then be analyzed using state space techniques to identify physiological information for the biological system. The described techniques can be implemented in a distributed cardiac activity monitoring system, including a cardiac monitoring apparatus, and a QRS detector thereof.
