Abstract

An optical target imaging system includes a tower structure supporting the system at the muzzle of the barrel, a cantilever system connected to and supported from the tower structure by a system of flexible tensioners extending in a distal direction from above an elevation of the muzzle to a distal end. A distal screen assembly is beneath the cantilever system at the distal end and holds a distal screen to intersect a path extending the barrel central axis. A proximal screen assembly holds a proximal screen to intersect the path extending the barrel central axis between the muzzle and the distal screen. In some embodiments, the distal screen is held with a lower extent nearer to the muzzle. The distal screen may be mounted to be rotatable around a median axle in the plane of the distal screen, with an actuator to articulate the distal screen around the median axle.

IPC Classes  ?

• F41G 3/32 - Devices for testing or checking

Abstract

A method is provided for assessing a risk of bone loss in a patient. The method includes receiving, at a processor, first data that indicates measured values of a panel of biomarkers in a sample from a patient. A value of each biomarker in the panel corresponds to a level of the biomarker in the sample. The method also includes determining, with the processor, second data that indicates a prediction that the patient has bone loss above a threshold value based on the first data and a classifier model. A method is also provided for determining the classifier model. A system is further provided for performing one of the disclosed methods.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Abstract

In one embodiment, a system for administering a chemical underwater to treat an underwater target comprises a UROV including a camera and a positioning device and a surface level control device to remotely control the UROV. A tube includes an inlet extending to an outlet of the tube which is attached to the positioning device of the UROV to position the outlet of the tube through which to deliver and dispense the chemical underwater within a field of view of the camera. A driver is configured to drive a medium from the inlet of the tube to the outlet of the tube to move the chemical through the tube to the outlet of the tube.

IPC Classes  ?

• B63G 8/00 - Underwater vessels, e.g. submarines
• A01N 61/00 - Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• B63C 11/52 - Tools specially adapted for working underwater, not otherwise provided for

Abstract

A stub base seal comprises a non-rotating slip-fit labyrinth seal to provide additional sealing properties. The labyrinth seal serves to capture errant gasses in the event of a partial leakage between the stub base and a concentric surrounding surface and leverages eddy flow effects to induce back flow impingement thereby reducing the flow rate through a leaking cavity.

IPC Classes  ?

• F16J 15/44 - Free-space packings
• F16J 15/02 - Sealings between relatively-stationary surfaces
• F16J 15/447 - Labyrinth packings
• F41A 3/76 - Obturating or packing devices for gas leak prevention in breech mechanisms specially adapted for sealing the gap between the forward end of the cartridge chamber and the rearward end of the barrel, e.g. sealing devices for revolvers or revolver-type guns

Abstract

Provided herein are hantivirus antibodies. These hantivirus antibodies bind to the Gn and/or Gc subunits of a hantavirus glycoprotein and have broad neutralizing activity against an epitope of different hantavirus species. Such antibodies are used in methods of inducing an immune response and methods of inhibiting hantavirus infection. Additionally provided are methods of treating an infectious disease using such antibodies.

IPC Classes  ?

• C07K 16/10 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 31/14 - Antivirals for RNA viruses

Abstract

An exoskeleton device includes a telescoping rod comprising at least one lower telescoping section and at least one upper telescoping section; a fracture stabilization orthosis; at least one fracture suspension mechanism connecting the lower telescoping section to the fracture stabilization orthosis; and a thigh corset connectable to the at least one upper telescoping section.

IPC Classes  ?

• A61H 3/00 - Appliances for aiding patients or disabled persons to walk about
• A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
• A61H 1/02 - Stretching or bending apparatus for exercising

Abstract

Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects. The methods of the invention further pertain to using the described algorithm to derive dosing regimens which can provide protection against symptomatic malaria in malaria-naïve, G6PD-normal subjects.

IPC Classes  ?

• A61K 31/4706 - 4-Aminoquinolines8-Aminoquinolines, e.g. chloroquine, primaquine
• A61P 33/06 - Antimalarials
• C07D 215/40 - Nitrogen atoms attached in position 8

Abstract

Provided are systems and methods for isolating melanins from a medium that include providing tangential filtration of the medium across a membrane with a 300 kilo Dalton or less cutoff. In some aspects, the methods and systems are suitable for large scale preparations due to the inherent established scalability of the unit operations employed herein. The systems and the methods can be utilized to purify melanins from fermented cell medium as well as from lysates generated therefrom.

IPC Classes  ?

• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
• B01D 65/02 - Membrane cleaning or sterilisation
• C07D 487/06 - Peri-condensed systems

Abstract

A method and apparatus for the intact recovery of ammunition projectiles. A high pressure fluid cutting device severs the casing of the ammunition cartridge, rearward on the cartridge beyond the rearward extent of the projectile. An automated feeding apparatus collects, orients, and feeds the first halves so severed to a separation press. The separation press includes a press ram, and a brace block. The brace block has a through opening sized to pass the projectile without alteration, and an internal side wall engaging the first half by the portion of the casing. The method includes a pressing force applied to the first half by contacting a rearward extent of the projectile, until the projectile separates from the portion of the casing.

IPC Classes  ?

• F42B 33/06 - Dismantling fuzes, cartridges, projectiles, missiles, rockets, or bombs

Abstract

A method for quantitatively evaluating the protective efficacy of a respiratory protection mask in an environment with a dynamic pollutant concentration, including providing a first air sampling unit and a second air sampling unit both electronically connected to a data acquisition system, obtaining a first pollutant reading of the environment with the dynamic pollutant concentration using the first air sampling unit, obtaining a second pollutant reading of the respiratory protection mask in the environment using the second air sampling unit, and determining a fit factor of the respiratory protection mask using the data acquisition system by dividing the first pollutant reading by the second pollutant reading. The method additionally includes determining a correction factor between the first air sampling unit and the second air sampling unit and applying the correction factor to the second air sampling unit using the data acquisition system.

IPC Classes  ?

• A62B 27/00 - Methods or devices for testing respiratory or breathing apparatus

Abstract

Embodiments of the current disclosure include energetic microcapsules, comprising: a core comprising a first energetic material; and a shell comprising a second energetic material encapsulating the core, wherein the first energetic material is different from the second energetic material, and wherein the core is 15% to 70% by weight of the energetic microcapsule and the shell is 30% to 85% by weight of the energetic microcapsule. Embodiments of the current disclosure further include methods of forming an energetic microcapsule, comprising: mixing an organic phase monomer and an aqueous phase monomer to form an emulsion; curing the emulsion at a predetermined temperature to form the energetic microcapsule; and coating the energetic microcapsule with a thermoplastic coating.

IPC Classes  ?

• C06B 45/24 - Compositions or products which are defined by structure or arrangement of component or product comprising a coated component the component base containing an organic explosive or an organic thermic component the coating containing an organic compound the compound being an organic explosive or an organic thermic component
• C06B 21/00 - Apparatus or methods for working-up explosives, e.g. forming, cutting, drying

Abstract

The present invention is directed to a casualty evacuation ecosystem. The ecosystem includes a Casualty Protection Unit (CPU) and a Casualty Collection Point Shelter (CCP), both of which provide shelter, heat, and care for a casualty. The CPU may include an inflatable structure and a waterproof material; at least one inflation port; and at least one heat source. The CCP may include at least one inflatable tent or tent-like structure having at least one portal capable of receiving a casualty protection unit.

IPC Classes  ?

• E04H 15/20 - Tents or canopies, in general inflatable, e.g. shaped, strengthened or supported by fluid pressure
• A61G 1/013 - Stretchers foldable or collapsible
• A61G 10/00 - Treatment rooms for medical purposes

Abstract

Two surface proteins of A. baumannii, which are required for iron transport of the bacteria, were identified: BauA, which is a siderophore receptor, and OmpW2, which are porins. Amino acid- and DNA sequences of monoclonal antibodies that bind to BauA and OmpW2 antigens were identified. These monoclonal antibodies were able to reduce bacterial growth and biofilm formation, and when they were applied together, they work in synergy. It was also demonstrated that these antibodies prevented infection in three separate animal models of infection. Thus, the invention provides pharmaceutically applicable compositions and methods of use thereof as well as a kit for outdoor use, based on these mouse monoclonal antibodies in order to develop human monoclonal antibodies against BauA and/or OmpW2 of A. baumannii as surface targets. These antibodies block their function and render the bacteria avirulent and bacteriostatic so it can be killed by the immune system.

IPC Classes  ?

• C07K 16/1218 -
• A61K 39/40 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum bacterial
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/04 - Antibacterial agents

Abstract

A fire extinguishing system and method includes a pressure vessel and a control module. The pressure vessel is charged with a predetermined mixture to a stored energy of greater than 100 bar*L/kg. The predetermined mixture includes a propellant gas and a fire extinguishing agent. The control module is configured to fully discharge the pressure vessel to a protected compartment in response to a fire threat detected in the protected compartment by at least one sensor in communication with the control module.

IPC Classes  ?

• A62C 35/02 - Permanently-installed equipment with containers for delivering the extinguishing substance
• A62C 3/07 - Fire prevention, containment or extinguishing specially adapted for particular objects or places in vehicles, e.g. in road vehicles
• A62C 35/13 - Permanently-installed equipment with containers for delivering the extinguishing substance controlled by a signal from the danger zone with a finite supply of extinguishing material

Abstract

A vehicle or shipping-container monitoring system is provided. The system is used to sample the interior environment of the container and if needed, clear a potentially hazardous material from the interior of the container prior to conventional opening. The system includes a monitoring assembly affixed to a first through-penetration in the vehicle container, an evacuation assembly affixed to a second through-penetration in the vehicle container, and an intake penetration with a cap affixed to a third through-penetration in the vehicle container. A method is also provided to assess the interior of a vehicle or shipping container for hazardous gases or vapors prior to opening the container.

IPC Classes  ?

• B65D 90/22 - Safety features
• B65D 90/48 - Arrangements of indicating or measuring devices

Abstract

Methods and apparatus for treating Peyronie's disease. In one embodiment, the method includes providing a plurality of inserts (34) with each insert (34) having a cavity (36) formed therein. Each cavity (36) is formed to receive and encapsulate the entire angulated penis of the patient. The degrees of angulation of the respective cavities (36) of the plurality of inserts (34) are a series of sequentially decreasing degrees of angulation that are all less than the initial degree of angulation of the angulated penis. The plurality of inserts (34) is used by the patient sequentially to gradually break down fibrotic plaque and gradually reshape the angulated penis with minimal discomfort to the patient. A stiff cylindrical housing (32) receives the plurality of inserts (34) in a sequential manner and creates a vacuum chamber (46) above each insert.

IPC Classes  ?

• A61F 5/41 - Devices for promoting penis erection

Abstract

An impact test system and method includes an arm that supports a helmeted headform in a mounted position. The arm includes a tube, collar, anti-rotation protrusion, and piston. The tube and collar are disposed about a translation axis. The collar is coupled to an end of the tube. The collar includes a lower contact surface the abuts a lower rear portion of the headform in the mounted position. The anti-rotation protrusion is coupled to the collar and includes an upper contact surface that is radially outward of the lower contact surface and abuts an upper rear portion of the headform in the mounted position. The piston extends within the tube for translation relative thereto along the translation axis between retracted and extended positions such that an end portion of the piston ejects the helmeted headform away from the collar toward an impact surface, free from the arm.

IPC Classes  ?

• G01N 3/307 - Investigating strength properties of solid materials by application of mechanical stress by applying a single impulsive force generated by a compressed or tensile-stressed springInvestigating strength properties of solid materials by application of mechanical stress by applying a single impulsive force generated by pneumatic or hydraulic means

Abstract

A method, system and apparatus determines an individual body composition by the summation of regional estimates determined from anatomical subregion geometry (e.g., lengths, surface areas, volumes). The anatomical subregion geometry may be based on a surface mesh presented by a 3D whole-body scanner. Regional composition estimates are produced by processing subregion geometry combinations by fitted weight values. The regional composition estimates are then summed to produce an individual body composition.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof
• G06T 7/00 - Image analysis
• G06T 7/60 - Analysis of geometric attributes

Abstract

A reloading firearm featuring a mechanism to reduce the blowback of toxic propellant gasses towards the warfighter. The reloading assembly acts in plural segments to increase the firing chamber-closed dwell time, while limiting adverse impact to the overall nominal rate of fire. Greater dwell time corresponds with reduced exposure of the warfighter to propellant gasses. Moreover, increasing the dwell time without otherwise altering the firing cycle has the additional effect of delaying the breech opening after the cartridge is fired. This delay in breech opening permits gas pressure at the muzzle, which may be elevated and/or constrained by flash and/or sound suppression, to dissipate before the breech is opened. Accordingly, when the breech opens later in the firing cycle, there is a reduced pressure gradient across the combination of barrel and firing chamber, which reduces a driving force of propellant gasses towards the warfighter via the open breech.

IPC Classes  ?

• F41A 5/18 - Mechanisms or systems operated by propellant charge energy for automatically opening the lock gas-operated
• F41A 5/24 - Mechanisms or systems operated by propellant charge energy for automatically opening the lock gas-operated by direct action of gas pressure on bolt or locking elements

Abstract

A continuous mixing technology is used to develop a continuous process as an alternative manufacturing technology to sigma-blade batch mixer process for producing flexible explosive formulations (e.g. Flex-X) that is composed of energetic solids and additives without any solvents. This continuous mixer's chamber is partially filled under atmospheric pressure with significant overhead space, reducing energetic hazards. The continuous mixing machine can be comprised with one or two temperature zones, wherein all ingredients are added subsequently into the mixing chamber.

IPC Classes  ?

• C06B 21/00 - Apparatus or methods for working-up explosives, e.g. forming, cutting, drying
• C06B 45/10 - Compositions or products which are defined by structure or arrangement of component or product comprising solid particles dispersed in solid solution or matrix the solid solution or matrix containing an organic component the organic component containing a resin

Abstract

An Ionosphere Correction Extrapolation (ICE) solution for correcting ionosphere-induced errors in a space-based positioning, navigation, and timing (PNT) signal uses a reference receiver to create a local ionosphere model. The ICE solution is able to accurately correct range measurements for single frequency or signals of opportunity user equipment (UE). The ICE solution produces a Vertical Total Electronic Content (VTEC) contour map that is centered with respect to a single dual-frequency reference receiver, such as a Global Positioning System (GPS) receiver and extending out to the visible horizon with respect to that reference receiver. The generated VTEC map enables the implementation of ionosphere correction without the need for a direct dual-frequency measurement.

IPC Classes  ?

• G01S 19/07 - Cooperating elementsInteraction or communication between different cooperating elements or between cooperating elements and receivers providing data for correcting measured positioning data, e.g. DGPS [differential GPS] or ionosphere corrections
• G01C 21/00 - NavigationNavigational instruments not provided for in groups

Abstract

An apparatus for assessment of swine includes a housing configured to accommodate swine: at least one response mechanism for recording responses by swine; a light located above and/or below the at least one response mechanism to provide stimuli to the swine; a partition to limit contact with the at least one response mechanism by the swine; and a food delivery and receptacle unit capable of measuring food retrieval by the swine. The apparatus may be used to perform tests on the swine.

IPC Classes  ?

• A61K 49/00 - Preparations for testing in vivo
• A01K 1/03 - Housing for domestic or laboratory animals
• A01K 5/00 - Feeding devices for stock or game
• A01K 29/00 - Other apparatus for animal husbandry
• A61D 7/00 - Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
• G01L 5/00 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes

Abstract

A boron nitride (BN)-polymer barrier that isolates and protects boron suboxide (nominally, B6O) and other carbon sensitive ceramic powders during the densification and sintering process is described. The BN-polymer barriers (or “systems”) may include formulations such as free-standing films, appliques (e.g., paints, sprays, coatings, etc.), and solution formulations. Such formulations may be able to be applied to elements such as a graphite mold, die, crucible, and/or graphite paper interlayer. The BN-polymer barrier systems provide superb protection for B6O ceramic powder from reaction with the carbon originating from graphite molds utilized during sintering, thus reducing the need to machine out and grind large portions of sintered ceramic parts where exposure to carbon transforms B6O ceramic into undesirable boron carbide (nominally, B4C). In addition, the polymer binder systems described herein will facilitate the future development of novel ceramic materials previously unavailable due to incompatibility with graphite mold material.

IPC Classes  ?

• C08K 3/38 - Boron-containing compounds
• C08J 3/21 - Compounding polymers with additives, e.g. colouring in the presence of a liquid phase the polymer being premixed with a liquid phase
• C08J 5/18 - Manufacture of films or sheets
• C08L 23/22 - Copolymers of isobuteneButyl rubberHomopolymers or copolymers of other iso-olefins

Abstract

In one embodiment, an asset protection system includes a first netting system and a second netting system. The first netting system includes first columns disposed around an asset, first springs connected to first column tops of the first columns, first cables connected to the first springs, and first nets connected to the first cables. The first nets include first interior nets surrounded by first peripheral nets which are connected to first cables connected to the ground. The second netting system includes second columns disposed around the asset, second springs connected to second column tops of the second columns, second cables connected to the second springs, and second nets connected to the second cables. The second nets include second interior nets surrounded by second peripheral nets which are connected to second cables connected to the ground. The first nets are disposed between the asset and the second nets.

IPC Classes  ?

• F41H 11/04 - Aerial barrages

Abstract

A strap pack tool is used to support a strap pack of a helicopter to allow easier, quicker and safer maintenance of rotor hub components. This is accomplished by a cylindrical hub extending upward from a main body of the strap pack tool for engaging the blade-root end of the strap pack. Side appendages connected to the main body are provided with arms having support platforms and respective hubs for engaging the disconnected ends of rotor dampers. An interior wall located within the main body forms a cavity for engaging a raised lip of a lower flange of a strap pack housing. The tool is made of thermoplastic material with the interior of the tool being of honeycomb construction with solid I-beams providing structural support to the arms.

IPC Classes  ?

• B64F 5/40 - Maintaining or repairing aircraft

Abstract

The disclosure provides a method and device for supporting the vertical and lateral loads on expedient ground surfaces. The disclosure provides a screw-type ground anchor with an external hollow stiffening cage to increase the ground anchor's lateral load bearing capacity and an anchor screw to provide vertical load bearing capacity without compromising its ease of installation. The anchor screw installs the stiffening cage concurrently while being installed by pressing down the stiffening cage while the anchor screw is rotated into the ground. By combining the stiffening cage with the anchor screw, rapid installation can be achieved while retaining lateral and vertical load bearing capacity.

IPC Classes  ?

• E02D 5/80 - Ground anchors
• E01C 9/00 - Special pavingsPavings for special parts of roads or airfields

Abstract

A loading apparatus includes an incident bar and a transmission bar coaxial with a specimen along a longitudinal axis. A loading gun has a gun barrel and a striker bar inside the gun barrel. The incident bar is disposed between the gun barrel and the specimen. A reaction spring is disposed between the gun barrel and a reaction mass. A pulse shaper is disposed between the reaction spring and the striker bar. The striker bar is propelled in a direction from the incident bar to the reaction spring to strike the pulse shaper and compress the reaction spring to apply a dynamic tensile load on the specimen in the direction along the longitudinal axis. A precompression device is coupled to the transmission bar to apply a quasi-static precompressive load on the specimen via the transmission bar before propelling the striker bar to the pulse shaper to generate the dynamic tensile load.

IPC Classes  ?

• G01N 3/10 - Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces generated by pneumatic or hydraulic pressure
• G01N 3/04 - Chucks

Abstract

In one embodiment, a protective device includes a first shell and a second shell. The second shell is configured to mate with the first shell to form a main chamber and a transition chamber of a housing. The main chamber is in fluidic communication with the transition chamber to form a whole chamber which is fluidicly sealed from an exterior of the housing and which is enclosed except for a transition opening between the transition chamber and the exterior. The transition opening is for receiving one or more fiberoptic cables to be housed within the main chamber. A foam is disposed in at least the main chamber to provide a soft cushion for one or more spliced ends of the one or more fiberoptic cables. A transition opening seal seals the transition opening around the one or more fiberoptic cables to form a water-tight enclosure around the whole chamber.

IPC Classes  ?

• G02B 6/44 - Mechanical structures for providing tensile strength and external protection for fibres, e.g. optical transmission cables

Abstract

An arrangement of a water pump, a slurry pump, a jet power log, and an arrangement of hoses provides a suction boosted sand delivery system to pump water, sand and indigenous fill materials to fill geotextile containers at a beach or littoral zone. The system is lightweight, portable, has a small footprint, and is easy to use and operate, requires little labor to implement and maintain, can be assembled by hand without specialty tools, and can be operated by just a few individuals. Methods for implementing the system to fill a geotextile sediment containment device are also provided.

IPC Classes  ?

• E02F 3/92 - Digging elements, e.g. suction heads

Abstract

In one embodiment, a fluorescence-based kit for detection and analysis of a toxin in a liquid sample includes a diluted antibody mixture in a preparation container to receive the liquid sample to produce a preparation solution; a fluorescent compound absorbed onto colloidal graphene in an analysis container to receive the preparation solution to produce an analysis solution; and a portable detector including one or more reference solutions each having a different one of a plurality of known levels of toxin concentration of the toxin, and a light source to shine a light onto the analysis solution and the one or more reference solutions.

IPC Classes  ?

• G01N 21/64 - FluorescencePhosphorescence
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

In one embodiment, a kit for airfield matting comprises a plurality of matting panels each including a rectangular mat core having a first side, a second side, a first end, and a second end. The first side has a first side connector. The second side has a second side connector. The first side connector of one matting panel of the plurality of matting panels is configured to couple with at least a part of the second side connector of one or more side neighboring matting panels of the plurality of matting panels to be connected therewith. The first end has a first end connector. The second end has a second end connector. The first end connector of one matting panel of the plurality of matting panels is configured to couple with the second end connector of an end neighboring matting panel of the plurality of matting panels to be connected therewith. In one embodiment, a kit for airfield matting comprises a plurality of matting panels each including a rectangular mat core having a first side, a second side, a first end, and a second end. The first side has a first side connector. The second side has a second side connector. The first side connector of one matting panel of the plurality of matting panels is configured to couple with at least a part of the second side connector of one or more side neighboring matting panels of the plurality of matting panels to be connected therewith. The first end has a first end connector. The second end has a second end connector. The first end connector of one matting panel of the plurality of matting panels is configured to couple with the second end connector of an end neighboring matting panel of the plurality of matting panels to be connected therewith. The matting panels each have a length of not greater than about 84 inches.

IPC Classes  ?

• E01C 9/08 - Temporary pavings

Abstract

In one embodiment, a kit for airfield matting comprises a plurality of matting panels each including a rectangular mat core having a first side, a second side, a first end, and a second end. The first side has a first side connector. The second side has a second side connector. The first side connector of one matting panel of the plurality of matting panels is configured to couple with at least a part of the second side connector of one or more side neighboring matting panels of the plurality of matting panels to be connected therewith. The first end has a first end connector. The second end has a second end connector. The first end connector of one matting panel of the plurality of matting panels is configured to couple with the second end connector of an end neighboring matting panel of the plurality of matting panels to be connected therewith. The matting panels each have a length of not greater than about 84 inches.

IPC Classes  ?

• E01C 9/08 - Temporary pavings

Abstract

In one embodiment, an extraction box includes a bottom, a right side wall, and a left side wall. A first wall forms a back wall on a back side of the extraction box. A second wall forms a front wall on a front side of the extraction box. The second wall is movable between a closed position to enclose the front side and an open position to open up the front side of the extraction box. A removable connector is removably attached to the right side wall and the left side wall to be disposed adjacent a top side of the extraction box, to be driven in a direction between the front side and the back side of the extraction box and to be lifted in an upward direction. The removable connector is removable from the extraction box to provide an open top side of the extraction box.

IPC Classes  ?

• G01N 1/12 - DippersDredgers
• G01N 33/24 - Earth materials

Abstract

The present disclosure provides compositions, systems, devices, and methods for the delivery of therapeutics. Particularly, the disclosure provides composition, systems, and devices of the delivery of Janus kinase (JAK) inhibitors and uses thereof, such as for inhibiting allograft rejection or treating autoimmune diseases.

IPC Classes  ?

• A61K 9/06 - OintmentsBases therefor
• A61K 9/51 - Nanocapsules
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection

Abstract

In one embodiment, a blast shield apparatus comprises: a blast resistant blanket having a blanket edge and a blanket center region; a plurality of blanket magnets disposed near the blanket edge and distributed along the blanket edge; and a chamber having a first side facing the blast resistant blanket and coupled to the blanket center region of the blast resistant blanket, and a second side opposite from the first side and facing away from the blast resistant blanket. The chamber includes a chamber interior to store a gas.

IPC Classes  ?

• F42D 5/05 - Blasting mats

Abstract

A sterilization device includes at least one flexible sheet; a plurality of violet-blue visible light light-emitting diodes (LEDs) at least partially or fully embedded in or attached to the at least one flexible sheet; and a housing having at least one reflective surface into which the at least one flexible sheet is insertable.

IPC Classes  ?

• A61L 2/08 - Radiation

Abstract

A surgical device includes an elongated handle and at least one cutting assembly at an end of the handle. The at least one cutting assembly includes an elevator, a retainer located above the elevator, and at least one cutting blade positioned between the elevator and the retainer. The surgical device may be used to cut tissue, such as dura mater during brain surgery.

IPC Classes  ?

• A61B 17/3205 - Excision instruments
• A61B 17/02 - Surgical instruments, devices or methods for holding wounds open, e.g. retractorsTractors
• A61B 17/32 - Surgical cutting instruments
• A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
• A61B 18/14 - Probes or electrodes therefor

Abstract

Methods, devices, systems, and computer-readable media are described that provide supervisory control of physiologic closed-loop controllers including: monitoring in real-time physiological state information of a patient and continuously determining from the physiological state information a plurality of casualty states of the patient; and in response to changes in two or more determined casualty states of the patient, simultaneously adaptively controlling and adjusting operation of a plurality of physiological closed-loop controllers (PCLCs) in accordance with a plurality of supervisory rules of a supervisory algorithm for casualty management (SACM) to harmonize operation of the PCLCs.

IPC Classes  ?

• G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
• G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 70/20 - ICT specially adapted for the handling or processing of medical references relating to practices or guidelines

Abstract

In one general embodiment, a process includes a repeated sequence of growing a first layer having a first type of electrically active dopant and growing a second layer having a second type of electrically active dopant, where the first type of electrically active dopant of the first layer is one of either a P-type or an N-type and the second type of electrically active dopant of the second layer is the other one of either the P-type or N-type.

IPC Classes  ?

• H10D 8/25 - Zener diodes
• H10D 8/01 - Manufacture or treatment

Abstract

A ballistic projectile recovery system includes a forward opening in an ogive of the projectile, selectively opened to deploy a portion of the recovery system. A parachute is deployable through the opening, connected to the projectile by riser line(s). A rotational bearing assembly makes the riser line(s) rotationally decoupled from the projectile. A bidirectional drag inducing element extends externally of an ogive of the projectile. A spacer, between a setback plate and the rotational bearing assembly, is deformable in at least the longitudinal direction of the projectile. The setback plate is movable between a first position to a second position made available by the compression of the spacer. In the second position, the setback plate is in contact with the projectile, providing a load path that avoids the rotational bearing assembly to take up strain applied to the projectile in at least the longitudinal direction.

IPC Classes  ?

• F42B 10/56 - Range-reducing, destabilising or braking arrangementsFall-retarding means of parachute type
• B64D 17/00 - Parachutes
• F42B 8/12 - Projectiles or missiles
• F42B 4/12 - Parachute or flare separation
• F42B 4/28 - Parachute flares

Abstract

A method for spatial calibration of an infrared (IR) camera allows for a large calibration area thereby providing high fidelity results for accurate long-distance measurement. Halogen lamps capable of being surveyed are spread over a relatively wide area to serve as calibration points for the infrared camera. The halogen lamps provide a precise and symmetric signature suitable for mid-wave IR cameras. An accurate model is developed for the radial and tangential distortion of the camera system. Likewise, values for the intrinsic parameters (focal lengths and optional skew coefficient) are measured to improve real-world measurements made using images recorded from a calibrated camera system.

IPC Classes  ?

• G06T 7/80 - Analysis of captured images to determine intrinsic or extrinsic camera parameters, i.e. camera calibration
• G01C 11/02 - Picture-taking arrangements specially adapted for photogrammetry or photographic surveying, e.g. controlling overlapping of pictures
• G01C 25/00 - Manufacturing, calibrating, cleaning, or repairing instruments or devices referred to in the other groups of this subclass
• H04N 17/00 - Diagnosis, testing or measuring for television systems or their details

Abstract

A composite panel holder having a plurality of layers, wherein each layer is a fiber matrix tape including a plurality of fibers immobilized in a matrix of a thermoplastic or thermoset polymer, and each layer is oriented at a different angle but in a same plane relative to a layer it is in direct contact with; and wherein the composite panel holder comprises six portions oriented in different directions, as viewed along a longitudinal axis of the panel holder. A method of preparing the composite panel holder that includes impregnating a plurality of fibers in a thermoplastic or thermoset polymer to form a matrix of fibers in the polymer, forming the matrix into a plurality of unidirectional tapes, stacking the tapes to form a composite structural panel with each of the tapes oriented in a different direction from adjacent tapes; and pressing the structural panel with a thermoforming press.

IPC Classes  ?

• B29C 70/42 - Shaping or impregnating by compression for producing articles of definite length, i.e. discrete articles
• B29C 70/08 - Fibrous reinforcements only comprising combinations of different forms of fibrous reinforcements incorporated in matrix material, forming one or more layers, with or without non-reinforced layers
• B29K 105/10 - Condition, form or state of moulded material containing reinforcements, fillers or inserts of continuous length, e.g. cords, rovings, mats, fabrics, strands or yarns oriented
• B29K 221/00 - Use of unspecified rubbers as reinforcement

Abstract

Various embodiments relate to application of a two-dimensional discrete cosine transform upon an area of interest of a spatial image to create a frequency domain image. A sub-area of the frequency domain image can be identified and its inverse can be taken. The intensity of the inverse can be used to classify the sub-area. In one example, how the intensity changes over time can be used to classify the sub-area.

IPC Classes  ?

• G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
• G06T 5/10 - Image enhancement or restoration using non-spatial domain filtering
• G06V 10/42 - Global feature extraction by analysis of the whole pattern, e.g. using frequency domain transformations or autocorrelation
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects

Abstract

The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.

IPC Classes  ?

• A61K 39/02 - Bacterial antigens
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 31/04 - Antibacterial agents

Abstract

An ocular chemical injury treatment ring comprises a substantially circular ring of a medical grade material and having a plurality of fenestrations or holes around a circumference of the circular ring.

IPC Classes  ?

• A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
• A61M 3/02 - EnemataIrrigators

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen. Limited evidence suggests that antibodies can protect humans against lethal CCHFV disease, but the protective efficacy of antibodies has never been evaluated in adult animal models. Here adult mice were used to investigate the protection provided by glycoprotein-targeting neutralizing and non-neutralizing monoclonal antibodies (mAbs) against CCHFV infection. A single non-neutralizing antibody (mAb-13G8) was identified that protected adult type I interferon deficient mice >90% when treatment was initiated prior to virus exposure and >60% when administered after virus exposure. Neutralizing antibodies known to protect neonatal mice from lethal CCHFV infection, failed to confer protection regardless of IgG subclass. The target of mAb-13G8 was identified as GP38, one of multiple proteolytically-cleaved glycoproteins derived from the CCHFV glycoprotein precursor polyprotein. Robust protection required complement activity, but not Fc-receptor functionality. Consistently, it was found that GP38 previously identified as a secreted molecule also localizes to viral envelope and cellular plasma membranes. This study reveals GP38 as an important antibody target for CCHFV and lays the foundation to develop novel vaccines and immunotherapeutic against CCHFV in human.

IPC Classes  ?

• C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
• A61K 39/12 - Viral antigens
• A61P 31/14 - Antivirals for RNA viruses
• C07K 16/10 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
• C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof

Abstract

Provided herein are methods and systems for measuring eye relief. A method for measuring eye relief generally includes placing an optical device on a support; inserting a measuring device into the support; extending a rod of the measuring device through a channel of the support into an eye-relief space of the optical device; contacting an end of the rod to the optical device; translating a locking device along the rod until the locking ring contacts the support; locking the locking ring in position by actuating a locking mechanism; and measuring a distance between an indicator on the rod and the locking ring; wherein the distance between the end of the rod and the indicator is equivalent to a length of the channel, such that the eye relief is the distance between the indicator and the locking ring.

IPC Classes  ?

• G02C 13/00 - AssemblingRepairingCleaning

Abstract

Various embodiments are described that relate an electrical current connector. The electrical current connector can be configured to provide electrical current when pressure is applied to a prong set. This pressure can cause a contact to engage with a connector. This can complete a circuit that allows the electrical current to flow. The connector can be coupled to a cable that can be configured to transfer data along with the electrical current. The cable can have an inner portion that transfers the data while an outer portion that surrounds the inner portion transfers the current.

IPC Classes  ?

• G01R 31/50 - Testing of electric apparatus, lines, cables or components for short-circuits, continuity, leakage current or incorrect line connections
• H01R 13/193 - Means for increasing contact pressure at the end of engagement of coupling part
• H01R 13/641 - Means for preventing, inhibiting or avoiding incorrect coupling by indicating incorrect couplingMeans for preventing, inhibiting or avoiding incorrect coupling by indicating correct or full engagement
• H01R 13/66 - Structural association with built-in electrical component
• H01R 13/703 - Structural association with built-in electrical component with built-in switch operated by engagement or disengagement of coupling parts

Abstract

The present invention is directed to an aqueous nanofluid composition and the method of use thereof for displacing or removing chemical warfare agents (CWAs) from capillary spaces, the nanofluid composition comprising water, colloidal silica, and at least one surfactant, such that the nanofluid composition is adjacent to the capillary features to absorb the CWAs from the capillary features. Upon displacement or removal, the CWAs are ready for disposal.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids
• A62D 3/30 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents
• A62D 101/02 - Chemical warfare substances, e.g. cholinesterase inhibitors
• A62D 101/26 - Organic substances containing nitrogen or phosphorus
• A62D 101/28 - Organic substances containing oxygen, sulfur, selenium or tellurium, i.e. chalcogen

Abstract

The disclosure relates to a dual-mode sensor and sensor array for eddy current testing and capacitive imaging, for example for use in non-destructive evaluation of a specimen to detect potential internal defects within the specimen. The sensor includes first and second concentrically aligned electrical coils coupled to an AC power source and an amplifier. The concentric electrical coils allow the dual-mode sensor to operate in an eddy current testing (ECT) mode or a capacitive imaging (CI) mode. In the ECT mode, the first electrical coil and the second electrical coil are electrically connected to the AC power source to provide magnetic field excitation and magnetic field pickup in the first and second electrical coils. In the CI mode, the first and second electrical coils are electrically connected to the AC power source such that the first and second electrical coils are charged electrodes in a disk-and-ring capacitor configuration.

IPC Classes  ?

• G01N 27/904 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables for investigating the presence of flaws using eddy currents with two or more sensors
• G01N 27/90 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables for investigating the presence of flaws using eddy currents

Abstract

In one embodiment, a method of identifying at least one rare earth element (REE) in at least one sample comprises: analyzing the at least one sample by inductively coupled plasma mass spectrometry (ICP-MS), which comprises measuring, identifying, and recording an estimated concentration based on counts per second of a target analyte REE proxy indicating a presence or absence of the target analyte REE proxy in the at least one sample via ICP-MS; and identifying the target analyte REE proxy in the at least one sample at a counts per second (CPS) intensity measurement screening level of equal to or greater than a minimum intensity measurement threshold to verify the presence or absence of the target analyte REE proxy.

IPC Classes  ?

• H01J 49/10 - Ion sourcesIon guns
• H01J 49/00 - Particle spectrometers or separator tubes

Abstract

A weapon accessory mount for removably mounting an accessory on a weapon. The weapon accessory mount includes an accessory rail supported by a base with a weapon attachment interface that engages the weapon. The weapon attachment interface includes an alignment pin that interfaces a portion of the weapon and a retaining pin that couples to an additional portion of the weapon. The accessory rail utilizes mounting grooves to interchangeably couple weapon accessories to the weapon accessory mount. Furthermore, accessory interference locators are located within some of the mounting grooves to define weapon-accessory-specific locations along the accessory rail, in which a weapon accessory should not be mounted to. Additionally, the weapon accessory mount is configured for mounting non-boresight aligned optics to a weapon and locating the non-boresight aligned optic in relation to the weapon to use in tracking a target.

IPC Classes  ?

• F41G 11/00 - Details of sighting or aiming apparatusAccessories

Abstract

A composition of matter including two optionally substituted phenol or optionally substituted aniline units separated by a furan spacer has been prepared. In particular, the chemical structure has a novolac bridge between the central furan ring and the two attached optionally substituted phenol and/or optionally substituted aniline units. These compounds can be modified to be used in various polymer resins. This new structure reduces toxicity relative to BPA/F, makes use of renewable chemicals, and produces certain beneficial polymer properties.

IPC Classes  ?

• C07D 407/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
• C07D 307/42 - Singly bound oxygen atoms
• C08F 222/20 - Esters containing oxygen in addition to the carboxy oxygen
• C08G 59/26 - Di-epoxy compounds heterocyclic

Abstract

A system including a main system 100 having a controller 102, a system database 104, and multiple handlers 110-116 that cooperate with a medical knowledge library 120 that may be part of the system or have one or more components external to the main system 100. The handlers 110-116 are configmed to provide a communication path between the controller 102 and external systems 150-159. The medical knowledge library 120 includes a control module 122, a rules engine 124, and a serial knowledge manager 127. In at least one embodiment, the rules engine 124 is configured to analyze facts provided by a handler 118 (between the controller 102 and the control module 122) to assess and provide suggested treatments to be communicated to a user through a user interface.

IPC Classes  ?

• G16H 70/20 - ICT specially adapted for the handling or processing of medical references relating to practices or guidelines
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Abstract

An apparatus for monitoring Intracranial Pressure (ICP) includes a non-invasive, flexible, wearable device (30), (60) with micro ultrasonic transducer arrays (32) fixed thereon. The wearable device (30), (60) is attached to the closed eyelid (21) of a conscious or unconscious patient with an adhesive (48). Using ultrasound sonography, the ultrasonic transducer arrays (32) on the wearable device (30), (60) image the optic nerve (26) behind the eyeball (20) to measure the Optical Nerve Sheath Diameter (ONSD). The ONSD provides an indication of the ICP in real time.

IPC Classes  ?

• A61B 8/08 - Clinical applications
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves

Abstract

Various embodiments are described that relate to energy generation. A housing can retain a spring coupled to a gear set. As the spring experiences linear compression and extension, the spring can cause rotational movement in the gear set. The rotational movement from the gear set can cause rotation of a rotational magnet. The rotational magnet, when rotated about a coil set, can convert an energy. The energy can be used to charge a battery.

IPC Classes  ?

• A45F 3/06 - Sacks or packs carried on the body by means of two straps passing over the two shoulders specially adapted for military purposes
• A45C 15/00 - Purses, bags, luggage or other receptacles covered by groups , combined with other articles
• A45F 3/00 - Travelling or camp articlesSacks or packs carried on the body
• A45F 5/00 - Holders or carriers for hand articlesHolders or carriers for use while travelling or camping
• H02J 7/32 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from a charging set comprising a non-electric prime mover
• H02K 7/116 - Structural association with clutches, brakes, gears, pulleys or mechanical starters with gears

Abstract

A simplified, gearless, passive z-axis 3d printer system is suitable for an elementary school which uses a slotted cam to convert x and y axis movement of the print head to adjust the z axis. More specifically, a low temperature 3d printer may use consumer crayons as the build material. The 3d printer system is designed such that it may be constructed of parts which may be 3d printed. The 3d printer system may further include a means of reclaiming and recasting the build material for reuse. The 3D printer system, and the reclaiming and recasting means may be part of a overall cyclic learning process. The 3D printer may be part of an overall learning process which may further include scanning and converting a 2D drawing to 3D format.

IPC Classes  ?

• B29C 64/232 - Driving means for motion along the axis orthogonal to the plane of a layer
• B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
• B29C 64/236 - Driving means for motion in a direction within the plane of a layer
• B29C 64/329 - Feeding using hoppers
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
• B33Y 70/00 - Materials specially adapted for additive manufacturing

Abstract

In one embodiment, a radiofrequency (RF) driven actuator includes: a first layer having a thiol-ene polymer, synthesized to have a formulation represented by PETMPx-EDTy-TMPAEz-TVSa, with subscripts x, y, z, and a referring to nonzero mol % of respective particular monomers in the formulation, including pentaerythritol tetra(3-mercaptopropionate) as PETMP, ethanedithiol as EDT, trimethylolpropane diallyl ether as TMPAE, and tetravinylsilane (TVS), x+y=100 and z+a=100; a third layer including regenerated cellulose, the third layer having a lower coefficient of thermal expansion (CTE) than the first layer; and a second layer including carbon nanotubes (CNTs) dispersed in a polymer matrix composite. The second layer is a middle layer disposed between the first layer and the third layer to form a composite structure.

IPC Classes  ?

• H01Q 17/00 - Devices for absorbing waves radiated from an antenna Combinations of such devices with active antenna elements or systems
• B32B 23/08 - Layered products essentially comprising cellulosic plastic substances comprising such substance as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin
• B32B 27/20 - Layered products essentially comprising synthetic resin characterised by the use of special additives using fillers, pigments, thixotroping agents
• B32B 27/36 - Layered products essentially comprising synthetic resin comprising polyesters

Abstract

Embodiments of the presently disclosed technology provide orthopedic braces that employ adaptive/variable stiffness metamaterials to emulate the strain-stiffening behavior of ligaments. These orthopedic braces may provide lower rigidity during low-demand/low-strain activities (e.g., normal gait movements) and increased rigidity under high-demand/high-strain activities (e.g., running and other movements that require larger ranges of motion and rotational velocities).

IPC Classes  ?

• A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
• A61L 15/12 - Stiffening bandages containing macromolecular materials

Abstract

The invention entails methods to detect and at least partially decontaminate an intact skin surface of a person suspected of exposure to harmful substance, such as cholinesterase inhibitors (i.e., nerve agents, carbamate pesticides), vesicants or synthetic opioids. The method uses a two-step film-forming composition, which indicates dermal contact of harmful substances, and at least partially decontaminate the skin surface if needed.

IPC Classes  ?

• A61K 49/00 - Preparations for testing in vivo
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61K 38/39 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
• A61P 39/00 - General protective or antinoxious agents

Abstract

In one embodiment, an enclosure device for a printed circuit board (PCB) includes: an enclosure wall structure enclosing an enclosure interior which has a PCB space in which to dispose the PCB, the enclosure wall structure including therein an internal geometry of a monolithic heat exchanger core of a monolithic heat exchanger having a plurality of internal channels, the enclosure wall structure including one or more vents; and one or more fans configured to drive air via one or more inlets from an enclosure exterior outside of the enclosure wall structure through the internal channels and out of the one or more vents. The enclosure wall structure is configured to block air flowing through the internal channels from entering the enclosure interior.

IPC Classes  ?

• G06F 1/20 - Cooling means
• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating
• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields

Abstract

An example protective material formed from a multilayered laminate is provided. The protective material includes a first layer including a microporous membrane supporting a material. The protective material includes a second layer positioned adjacent to the first layer. The second layer includes porous membrane supporting a bed of a metal organic framework (MOF). The combination of the first and second layers provides a barrier against toxic vapors/gases, while allowing for moisture transmission, resulting in protection and comfort to the user.

IPC Classes  ?

• C08K 3/20 - OxidesHydroxides
• C08J 5/18 - Manufacture of films or sheets

Abstract

A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber.

IPC Classes  ?

• B01D 61/02 - Reverse osmosisHyperfiltration
• B01D 61/10 - AccessoriesAuxiliary operations
• B01D 61/12 - Controlling or regulating
• B01D 65/02 - Membrane cleaning or sterilisation
• C02F 1/00 - Treatment of water, waste water, or sewage
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic fever disease in humans. Currently, no licensed CCHF vaccines exist, and the protective epitopes remain unclear. Here, we tested a DNA vaccine expressing the M-segment glycoprotein precursor gene (GPC) of the laboratory CCHFV strain CCHFV-IbAr 10200 (CCHFV-M10200). Increasing the dose of CCHFV-M 10200 provides complete protection from homologous CCHFV challenge in mice, and significant (80%) protection from challenge with the clinically relevant, heterologous CCHFV-Afg09-2990 strain. We also report complete protection from CCHFV-Afg09-2990 challenge following vaccination with a CCHFV-Afg09-2990 GPC expressing DNA vaccine (CCHFV-M Afgog). Finally, we show that the non-structural M-segment protein, GP38, influences CCHF vaccine immunogenicity and provides significant protection from homologous CCHFV challenge. Our results demonstrate that M-segment DNA vaccines elicit protective CCHF immunity and further illustrate the immunorelevance of GP38.

IPC Classes  ?

• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61K 39/12 - Viral antigens
• A61P 31/14 - Antivirals for RNA viruses
• C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
• C12N 15/86 - Viral vectors

Abstract

A device is provided that can be rapidly decontaminated in response to exposure to toxic chemicals and biological materials. The device combines electroluminescence (EL) surfaces and panels with a reactive coating including a dye that acts to neutralize toxic chemical and biological materials. A current is applied to an EL display that has been coated with a fluorescent dye. The dye in turns converts nearby ambient oxygen to the more reactive singlet oxygen form that is responsible for the decontamination of toxic chemicals and agents in proximity to the device. Potential uses of the reactive decontamination device include surface panels of vehicles, exterior and interior surfaces of buildings, furniture, wands, and flexible surfaces such as tarps for tents, as well as fabrics and textiles, both woven and non-woven.

IPC Classes  ?

• A61L 2/08 - Radiation
• A62D 3/30 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents
• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 23/42 - Platinum
• B01J 35/39 - Photocatalytic properties

Abstract

A fracture stabilization orthosis includes a fabric or fabric wrap and a plurality of struts, each strut comprising two or more sheets of a material conformable to contours of a leg and insertable into a sleeve or pocket on the fabric or fabric wrap. The fabric or fabric wrap is shaped so that when it is wrapped around a limb it forms a frustum.

IPC Classes  ?

• A61F 5/058 - Splints
• A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces

Abstract

Protective eyewear that may provide a full field of view while shielding users from unsafe, harmful, or unwanted visual elements, including high-intensity sources such as lasers, is described. Such shielding may include, for instance, capturing, attenuating, transforming, filtering, and/or otherwise processing such unsafe, harmful, or unwanted visual elements for presentation to users. The protective eyewear may enhance visual elements, such as by increasing brightness or contrast. The protective eyewear may allow users to see visual elements outside their normal or expected range such as ultraviolet and infrared. The protective eyewear may include one or more cameras that may capture visual information associated with the user environment. The captured information may be analyzed and processed such that harmful or unwanted visual elements are removed and/or otherwise processed to be made safe for viewing. After processing, the captured information may be rendered and provided via a display of the protective eyewear.

IPC Classes  ?

• A61F 9/02 - Goggles

Abstract

Inventors unexpectedly discovered and claim a method of managing clinical outcomes using clinical outcome burn patient management system and method to curate a panel of optimum number of biomarkers to describe the clinical outcome variable with maximum efficacy for clinicians managing treatment and determining clinical outcomes for burn patients.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Abstract

Various embodiments that pertain to private permissioned hierarchical blockchains are described over fog/edge and multi-Cloud computing networks. In one example, a blockchain component can manage a private permissioned blockchain. An engagement component can engage a user with a network by way of the private permissioned blockchain. The network can be of different configurations, such as comprising at least one node (e.g., a first node and a second node) as well as being an access network, a backbone network, or a hybrid network. A communication component can enable a communication with the user and the network, such as the first node, by way of the private permissioned blockchain.

IPC Classes  ?

• H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols

Abstract

2/hr. The impermeable clay-platelet filler component includes an aspect ratio having a ratio of diameter to thickness of 10 to 1 or greater. The impermeable clay-platelet filler component and the permeable metal-organic framework filler component each has at least a 20 weight percent of the film.

IPC Classes  ?

• B01D 71/02 - Inorganic material
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/12 - Composite membranesUltra-thin membranes
• B01D 71/52 - Polyethers
• C08J 3/20 - Compounding polymers with additives, e.g. colouring
• C08J 5/18 - Manufacture of films or sheets

Abstract

A low-cost objective lens design uses only ZnS optical material, suitable for use with an uncooled infrared bolometer having a curved focal plane. Its objective lens field of view is at least ±20.0° over a 1280×720 pixel array with 0.0012 mm pitch. Lens chromatic aberrations are corrected over at least the 8-11 micron infrared wavelength band. The objective lens operates at a relatively fast F #/1.0 which is common in the art for bolometer applications.

IPC Classes  ?

• G02B 13/14 - Optical objectives specially designed for the purposes specified below for use with infrared or ultraviolet radiation
• G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,

Abstract

This invention relates to a wholly recombinant four factor hemostatic complex concentrate (4F-PCC) composition, human liver cell-produced product. Methods of producing a hemostatic composition using a hepatocyte cell line and a CRISPR/Cas9 gene activation multiplexing, which allows for simultaneous and high level expression of the FII, FVII, FIX, and FX clotting factors. The resultant product is a recombinant resuscitation solution to aid in mitigation of coagulopathy, reversal of coagulopathic states, and fluid resuscitation.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 38/36 - Blood coagulation or fibrinolysis factors
• C07K 14/75 - Fibrinogen
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12N 9/22 - Ribonucleases
• C12N 9/64 - Proteinases derived from animal tissue, e.g. rennin
• C12N 9/74 - Thrombin
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 15/90 - Stable introduction of foreign DNA into chromosome
• C12P 21/00 - Preparation of peptides or proteins

Abstract

A bullet tracking system comprising a sensor sub-system that generates bullet tracking data by tracking a position and range of a bullet discharged from a remote-controlled weapon and traveling to an intended target; a processor that processes the bullet tracking data to determine aim adjustments of the weapon for subsequent firing of bullets to compensate for tracked bullet ballistics to improve an accuracy of the bullets for reaching the intended target; and a control sub-system to make the aim adjustments of the weapon.

IPC Classes  ?

• F41G 3/14 - Indirect aiming means
• F41G 3/16 - Sighting devices adapted for indirect laying of fire
• F41G 5/06 - Elevating or traversing control systems for guns using electric means for remote control

Abstract

A multi-compartment mortar increment container (MIC) enables burning of two propellants to broaden the pressure-time curve providing additional energy and force behind a mortar shell while maintaining allowable pressures. During the ballistic cycle, the mortar increment container burns allowing the faster propellant to mix with the slower propellant. The slower propellant will burn later in the ballistic cycle generating higher pressure behind the projectile leading to higher velocity.

IPC Classes  ?

• F42B 5/192 - Cartridge cases characterised by the material used

Abstract

A battery activation device uses ballistic pressure to directly activate a liquid reserve battery and simultaneously complete the battery ground circuit to the electronics system. The gas pressure generated during ballistic launch reacts upon a piston face that transforms the pressure directly into a linear force which is then applied to the liquid reserve battery for activation. An internal shear disc prevents unintentional battery activation from an accidental drop and if sufficient launch pressure has not been realized by device.

IPC Classes  ?

• H01M 6/38 - Deferred-action cells containing electrolyte and made operational by physical means, e.g. thermal cells by mechanical means
• F42C 15/33 - Arming-means in fuzesSafety means for preventing premature detonation of fuzes or charges operated by change of fluid pressure by breaking a vacuum or pressure container
• H01M 50/682 - Containers for storing liquidsDelivery conduits therefor accommodated in battery or cell casings

Abstract

Solid fuel pellets or particles are coated with a diamond-like and/or graphitic coating to impart increased resistance to oxidation or other forms of degradation. An apparatus and method for producing solid fuel pellets or particles or other comminuted or particulate material that are coated with diamond-like and/or graphitic coatings employ plasma coating of the particles or comminuted material in a plasma chamber that has provision for agitating and/or stirring the particles during the plasma coating process. The gas feed to the plasma chamber may contain at least one organic carbon source.

IPC Classes  ?

• C10L 5/32 - Coating
• B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
• C23C 16/02 - Pretreatment of the material to be coated
• C23C 16/26 - Deposition of carbon only
• H01J 37/32 - Gas-filled discharge tubes

Abstract

In one embodiment, an additive construction method includes printing a calibration print out of a cement-based material using a 3D printer having a pump to pump the cement-based material and having a gantry operating at a gantry feed rate under control of an additive manufacturing software to dispense the cement-based material; measuring a bead width along a length of the calibration print; performing curve fitting on bead width measurements of the bead width to produce a calibration print process map that correlates the bead width of the calibration print to the gantry feed rate of the 3D printer to provide a calibration print correlation; and, if all of one or more desired bead widths for an additive construction print fall within the range of bead widths of the calibration print process map, using the calibration print correlation to modify bead width parameters of the additive manufacturing software for operating the 3D printer to perform bead width manipulation for the additive construction print.

IPC Classes  ?

• G05B 19/4099 - Surface or curve machining, making 3D objects, e.g. desktop manufacturing

Abstract

In one embodiment, a system for cleaning a well includes (i) an ultraviolet (UV) light emitting device and/or (ii) a first brush connected with an abrasion device motor to drive the first brush in rotation around a longitudinal axis of the first brush. A cable reel and a cable are connected with (i) the UV light emitting device to power the UV light emitting device, to lower the UV light emitting device into the well, and to raise the UV light emitting device from the well; and/or (ii) the first brush and the abrasion device motor, to power the abrasion device motor, to lower the first brush and the abrasion device motor into the well, and to raise the first brush and the abrasion device motor from the well.

IPC Classes  ?

• E21B 37/00 - Methods or apparatus for cleaning boreholes or wells
• B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
• B08B 7/04 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass by a combination of operations
• B08B 17/02 - Preventing deposition of fouling or of dust
• E21B 19/02 - Rod or cable suspensions
• E21B 19/084 - Apparatus for feeding the rods or cablesApparatus for increasing or decreasing the pressure on the drilling toolApparatus for counterbalancing the weight of the rods with flexible drawing means, e.g. cables

Abstract

For see-through AR displays, the current state of art uses geometric correction to lower the display location error, however this is far from an ideal solution and requires knowing range or pose of the devices. A dual-function optic for eye display & camera is disclosed, wherein a sensor camera imaging optics pipeline with a virtual projection point at an eye's retina reduces parallax errors to zero.

IPC Classes  ?

• G02B 27/01 - Head-up displays
• G02B 27/10 - Beam splitting or combining systems
• G02B 27/30 - Collimators

Abstract

In one embodiment, an enclosure device for a printed circuit board (PCB) includes an enclosure wall structure enclosing an enclosure interior which has a PCB space in which to dispose the PCB. The enclosure wall structure includes therein an internal geometry of a monolithic heat exchanger core of a monolithic heat exchanger having a plurality of internal channels. The enclosure wall structure includes one or more vents. One or more fans are configured to drive air via one or more inlets from an enclosure exterior outside of the enclosure wall structure through the internal channels and out of the one or more vents. A plurality of misters are disposed at a plurality of misting locations external of the enclosure wall structure to deliver a misting fluid to the plurality of misting locations for cooling an exterior of the enclosure wall structure.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating
• G06F 1/20 - Cooling means

Abstract

In one embodiment, a cold mix asphalt composition comprises an aggregate blend including an aggregate and a filler; and a cold mix asphalt binder including a urethane-modified asphalt binder mixed with the aggregate blend to form the cold mix asphalt composition.

IPC Classes  ?

• C08L 95/00 - Compositions of bituminous materials, e.g. asphalt, tar or pitch

Abstract

A single-axis optical free-space communication device is described. The optical communication device may interact with entities that include or utilize elements such as retroreflectors. The optical communication device may be utilized for applications such as positioning, navigation, and/or timing (PNT), two-way communication, and/or other appropriate applications. The communication device may generate an optical output via a laser transmitter, optical fiber, and collimation lens. The optical communication device may receive optical inputs via the collimation lens, a photodetector, and receiver electronics. The optical communication device may utilize a single communication axis for transmission and reception by running an optical fiber transmission output through the center of an annular photodetector that receives reflected responses from the retroreflectors.

IPC Classes  ?

• H04B 10/00 - Transmission systems employing electromagnetic waves other than radio-waves, e.g. infrared, visible or ultraviolet light, or employing corpuscular radiation, e.g. quantum communication
• H04B 10/11 - Arrangements specific to free-space transmission, i.e. transmission through air or vacuum
• H04B 10/50 - Transmitters
• H04J 14/00 - Optical multiplex systems

Abstract

A parabolic mixing nozzle including a body having an internal flow channel having a well and a plurality of parabolic shaped channels extending through the well and wherein each of the plurality of parabolic shaped channels converge together and open into an exit passage to disrupt the laminar flow of material through the parabolic mixing nozzle and a method of making products using the parabolic mixing nozzle.

IPC Classes  ?

• B29C 45/20 - Injection nozzles
• B01F 25/432 - Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flowsCross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
• B01F 25/433 - Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
• B01F 25/46 - Homogenising or emulsifying nozzles
• B29C 45/17 - Component parts, details or accessoriesAuxiliary operations
• B33Y 80/00 - Products made by additive manufacturing
• B01F 101/00 - Mixing characterised by the nature of the mixed materials or by the application field
• B29K 105/24 - Condition, form or state of moulded material cross-linked or vulcanised

Abstract

An additive manufactured enhanced sidearm comprising an ejectable barrel group assembly having two barrels, each with a chamber, in an under and over configuration thereby forming a top and bottom, and preloaded with keyed rounds having a series wherein each of said projectiles is keyed via a keyway in a chamber in said barrel, each of said projectiles in said barrel group are keyed having 0 to 4 keyways formed in the side of the projectile said projectiles having a propellant and primer means disposed behind said projectile in said chamber, a series of electrical contacts disposed within said chambers in communication with said primer means, a rail disposed at the bottom of the barrels with a locking notch means, a battery disposed with said ejectable barrel group, a grip assembly in communication with said ejectable barrel group assembly said grip assembly comprising a hand grip, a pc board disposed within said hand grip, a trigger group disposed upon said pc board, a high voltage generator circuit disposed on said pc board, at least one recoil plate assembly disposed upon said pc board, at least one microprocessor disposed upon said pc board, and a removable safety block that interferes with the batter to pc board connection.

IPC Classes  ?

• F41A 21/06 - Plural barrels
• F41A 21/48 - Barrel mounting means, e.g. releasable mountings for replaceable barrels
• F41C 3/00 - Pistols
• F42C 11/00 - Electric fuzes
• B33Y 80/00 - Products made by additive manufacturing

Abstract

In this disclosure, a zebrafish model is established for rapid screening of potential drug candidates for prevention and treatment of sepsis. To this end, three endpoints (mortality, tail-fin edema, and reactive oxygen species detection) screening method is established to identify drugs of potential use among approved drugs and/or novel small molecules, and 16 drugs were identified, which target serotonin receptors, receptor tyrosine kinases, dietary supplements, antihistamine drugs, serotonin uptake inhibitors, monoamine oxidase inhibitors, and other antipsychotic drugs.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The disclosure provides a compact ultra-wideband (UWB) antenna comprising a plurality of sub-radiator segments, the plurality of sub-radiator segments being a flare section, an inductive corner section, and a rib section. The inductive corner section is configured to mount to a ground surface and connects the flare section and the inductive corner section. The UWB operates over a wide frequency range of 2-18 GHz with good impedance match, high forward gain, stable phase center, and consistent radiation performance. The UWB antenna further comprises a feed point. The feed point is configured to receive a coaxial connector. The plurality of sub-radiator segments are each optimized to propagate electromagnetic currents during specific frequency ranges within the wide frequency range of 2-18 GHz. Further, the UWB antenna can be a single monolithic material, such as a metallic aluminum.

IPC Classes  ?

• H01Q 5/25 - Ultra-wideband [UWB] systems, e.g. multiple resonance systemsPulse systems
• H01Q 5/335 - Individual or coupled radiating elements, each element being fed in an unspecified way using frequency dependent circuits or components, e.g. trap circuits or capacitors at the feed, e.g. for impedance matching

Abstract

A nano- structured alloy material includes a nanoparticle; a matrix phase surrounding the nanoparticle; and an alkali/ alkali Earth metal to alter (i) a material property of the nanoparticle, (ii) a material property of the matrix phase, and (iii) an interaction of the nanoparticle with the matrix phase.

IPC Classes  ?

• C22C 9/00 - Alloys based on copper
• C22C 1/04 - Making non-ferrous alloys by powder metallurgy
• B22F 3/10 - Sintering only
• B22F 1/00 - Metallic powderTreatment of metallic powder, e.g. to facilitate working or to improve properties

Abstract

The present disclosure relates to methods and compositions used therein to dye via a bifunctional diazirene compound high-performance textiles including para-aramid (polymers of co-polymers), ultra-high molecular weight polyethylene (UHMWPE), or nylon as filament yarns and/or spun yarns of fibers or fiber-blends thereof and in a manner more quickly and more environmentally friendly.

IPC Classes  ?

• D06P 1/00 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed
• D02G 3/02 - Yarns or threads characterised by the material or by the materials from which they are made
• D06P 1/384 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed using reactive dyes with a reactive group not directly attached to the heterocyclic group

Abstract

A portable decontamination chamber including an outer container defining a first internal volume; an interior receptacle positioned within the first internal volume and defining a second internal volume that is configured to receive an item to be decontaminated; an insulating liner configured to be positioned within the first internal volume between an interior surface of the outer container and an exterior surface of the interior receptacle; a thermite compact configured to be positioned within the first internal volume and in contact with at least a portion of the exterior surface of the interior receptacle; and an initiator configured to ignite the thermite compact to induce a biological decontamination temperature within the second internal volume in order to thoroughly and rapidly decontaminate material tainted with unwanted biological matter in a readily deployable package without the generation of additional gaseous products that increase the pressure within the decontamination chamber.

IPC Classes  ?

• A61L 2/04 - Heat
• A61L 2/26 - Accessories
• C06B 33/12 - Compositions containing particulate metal, alloy, boron, silicon, selenium or tellurium with at least one oxygen supplying material which is either a metal oxide or a salt, organic or inorganic, capable of yielding a metal oxide the material being two or more oxygen-yielding compounds
• F42B 3/11 - Initiators therefor characterised by the material used, e.g. for initiator case or electric leads
• F42B 3/113 - Initiators therefor activated by optical means, e.g. laser, flashlight

Abstract

A method for treating traumatic brain injury include administering to a patient having traumatic brain injury and in need of treatment an effective amount of a composition comprising resveratrol triacetate or esterified resveratrol. The traumatic brain injury may be a penetrating brain injury.

IPC Classes  ?

• A61K 31/222 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
• A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
• A61K 31/221 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
• A61K 31/66 - Phosphorus compounds
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 39/06 - Free radical scavengers or antioxidants

Abstract

Electric field sensors based on Rydberg atoms and their unique capabilities, relative to traditional sensors, are used for detecting radio frequency (RF) signals. Simultaneous demodulation and detection of multiple RF tones spanning nearly two decades (six octaves) are provided. The continuous recovery of the phase and amplitude of each tone and the sensitivity of the system and its bandwidth capabilities for multiband detection are provided. A digital communication protocol is also provided that simultaneously receives on-off-keyed binary data from four bands spanning nearly one decade of frequency.

IPC Classes  ?

• G01R 29/08 - Measuring electromagnetic field characteristics

Abstract

Methods, devices, systems, and computer-readable media are described for providing adaptive and closed loop hemorrhagic shock resuscitation. A computing device may cause activation of an automated tourniquet configured to impede extremity bleeding. The computing device may additionally cause activation of an adaptive resuscitation controller by determining a desired mean arterial pressure setpoint and causing, based on the desired mean arterial pressure setpoint, the adaptive resuscitation controller to infuse fluids into the patient. The computing device may then monitor component pressure measurements of the automated tourniquet and blood pressure parameters of the patient. The computing device may then, based on the component pressure measurements, cause modification of one or more operating parameters of the automated tourniquet. The computing device may additionally and/or alternatively, based on comparing the blood pressure parameters to the desired mean arterial pressure setpoint, cause the adaptive resuscitation controller to infuse fluids into the patient.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/02 - Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
• A61B 5/021 - Measuring pressure in heart or blood vessels
• A61B 17/00 - Surgical instruments, devices or methods
• A61B 17/132 - Tourniquets
• A61B 17/135 - Tourniquets inflatable
• A61M 5/142 - Pressure infusion, e.g. using pumps
• G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
• G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation

Abstract

A method of treating thrombosis in a subject comprising administering an effective amount of a PDE4 inhibitor.

IPC Classes  ?

• A61K 31/44 - Non-condensed pyridinesHydrogenated derivatives thereof
• A61K 31/727 - HeparinHeparan
• A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes

Abstract

A majority of military casualties occur during the pre-hospital period. The cause of death is largely associated with massive traumatic bleeding that leads to organ damage due to sustained hypoxia. Currently, therapeutics are lacking at the point of injury to mitigate hypoxic damage and maintain the survivability of severe hemorrhage prior to reaching medical facilities. This invention addresses that by introducing a method of co-administering prolyl hydroxylase domain inhibitor (PHDi, MK-8617), anti-fibrinolytic agent (tranexamic acid), and bradykinin receptor antagonist (icatibant) as anti-hemorrhage agents in combination with resuscitation fluid treatment with colloid solution of 25% human albumin that has an advantage of relatively small volume requirement to maintain blood volume. In addition, a kit comprising anti-hemorrhage agents that can be easily carried to the battlefield is also provided here. The therapeutic application of those agents on or near the point of injury can stabilize hypoxia inducible factor-1 alpha and enhance blood clot formation, which improves the patient's cellular adaptation to hypoxia and reduce hemorrhage, and thus can decrease organ failure and increase the patient's survivability.

IPC Classes  ?

• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• A61P 9/00 - Drugs for disorders of the cardiovascular system

Abstract

Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein.

IPC Classes  ?

• C07D 271/06 - 1,2,4-OxadiazolesHydrogenated 1,2,4-oxadiazoles
• C06B 25/34 - Compositions containing a nitrated organic compound the compound being a nitrated acyclic, alicyclic or heterocyclic amine

IPC Classes  ?

• C07K 16/10 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Abstract

The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and an ionic liquid, and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

Abstract

An apparatus for testing personal protection equipment or devices comprising an enclosure body having an air-inflatable support structure that receives an air-transferable chemical and air to maintain a substantially rigid structural integrity; a nozzle connected to the air-inflatable support structure, wherein the nozzle releases air and the air-transferable chemical from the air-inflatable support structure into the interior of the enclosure body for a selected period of time as a concentration of the air-transferable chemical in the interior of the enclosure body is at a steady state of uniformity; and a panel integrated into the enclosure body that passively releases air from the enclosure body.

IPC Classes  ?

• G01N 17/00 - Investigating resistance of materials to the weather, to corrosion or to light
• B01L 1/00 - EnclosuresChambers
• B01L 1/02 - Air-pressure chambersAir-locks therefor
• E04H 15/20 - Tents or canopies, in general inflatable, e.g. shaped, strengthened or supported by fluid pressure
• G01M 3/02 - Investigating fluid tightness of structures by using fluid or vacuum

Abstract

We disclose an ultrawide-band (USB) dual polarization three-dimensional (3D) tapered aperture Vivaldi antenna. It is generally comprised of a radiator having two pairs of tapering arms, each pair corresponding to a different polarization and the tapering arms spaced thereof closest to one another at a feed point location of the antenna and taper outwardly in opposite directions, thus forming a 3D Vivaldi antenna aperture therebetween; and a dual feed balun connecting to each of the two pairs of tapering arms and providing a separate channel for each of the polarizations. Embodiments of our antenna have been designed and simulated using full-wave electromagnetics commercial software. The results for our antennas demonstrate over 20:1 operating bandwidth with good radiation characteristics and very low cross polarization.

IPC Classes  ?

• H01Q 13/08 - Radiating ends of two-conductor microwave transmission lines, e.g. of coaxial lines, of microstrip lines
• H01P 3/06 - Coaxial lines
• H01Q 21/24 - Combinations of antenna units polarised in different directions for transmitting or receiving circularly and elliptically polarised waves or waves linearly polarised in any direction