The present invention relates to a bioreactor for RNA in vitro transcription, a method for RNA in vitro transcription, a module for transcribing DNA into RNA and an automated apparatus for RNA manufacturing. Further, the use of a bioreactor for RNA in vitro transcription as described herein is part of the present invention.The present invention relates to an RNA in vitro transcription reactor designed to be operable in an automated manner under GMP-compliant conditions. In particular, said RNA in vitro transcription reactor allows repetitive use of DNA template for various RNA in vitro transcription reactions. Further, the invention relates to an apparatus for RNA manufacturing comprising (a) a module for template DNA synthesis, (b) a module for transcribing DNA into RNA comprising said RNA in vitro transcription reactor, and, optionally, (c) a module for RNA formulation.
A method and an apparatus for applying sealing profiles to vehicle bodies or parts thereof, includes drawing off the sealing profile from an unwinding unit and rolling the sealing profile onto the vehicle body or the part of the vehicle body along an application line provided for application purposes, by a pressure-exerting roller of an application head. An arrangement of an automatic optical inspection system within the application apparatus provides for direct detection of defects and discontinuities of the sealing profile by the user without any need for markings on the sealing profile wound up on the roll or for data handling between the manufacturer of the sealing profile and the user.
B23P 19/04 - Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformationTools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
B60J 10/34 - Sealing arrangements characterised by the fastening means using adhesives
B60J 10/24 - Sealing arrangements characterised by the shape having tubular parts
3.
Method for fitting sealing profiles, by way of an adhesive layer, on vehicle bodies or the parts thereof
A method for fitting sealing profiles on vehicle bodies or the parts thereof includes withdrawing the sealing profile from an unwinding unit and, by way of an adhesive layer arranged on the sealing profile, rolling of the application device the sealing profile on the vehicle body or the part of the vehicle body, along an application line provided for fitting purposes, by a pressure-exerting roller of an application head. Defects and discontinuities in the sealing profile are detected immediately by the arrangement of an automatic optical inspection system within the application device, on the user side, i.e., in particular without there being any need for markings on the wound-up sealing profile or for data handling between the manufacturer of the sealing profile and the user.
B23P 19/04 - Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformationTools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
B25J 11/00 - Manipulators not otherwise provided for
4.
Method and device for determining the elongation and/or compression of a profiled sealing element
A method for determining the elongation and/or compression of a profiled sealing element applied to a body includes drawing the profiled sealing element, which exists as an endless profiled element, from a store and, with the help of an application roller and by means of an adhesive surface present on the profiled sealing element, rolling the profiled sealing element onto the body part along a line intended for the attachment. A measuring roller, which rolls on the profiled sealing element without slip, is arranged at a small distance before a drive system for the profiled sealing element. The length sensed by the measuring roller corresponds to the length of the profiled sealing element applied to the body along an application distance having a defined length.
B23P 19/04 - Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformationTools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
B60J 10/35 - Sealing arrangements characterised by the fastening means using adhesives using adhesive tapes, e.g. double-sided tapes
B65H 35/00 - Delivering articles from cutting or line-perforating machinesArticle or web delivery apparatus incorporating cutting or line-perforating devices, e.g. adhesive tape dispensers
5.
METHOD FOR FITTING SEALING PROFILES, BY WAY OF AN ADHESIVE LAYER, ON VEHICLE BODIES OR THE PARTS THEREOF
The invention relates to a method and an apparatus for fitting sealing profiles (2) on vehicle bodies or parts thereof, wherein the sealing profile (2) is withdrawn from an unwinding unit (7) and, by way of an adhesive layer arranged on the sealing profile, is rolled on the vehicle body or part of the vehicle body, along an application line provided for fitting purposes, by means of a pressure-exerting roller of an application head (4). The invention is based on the concept of defects and discontinuities in the sealing profile (2) being detected immediately by the arrangement of an automatic optical inspection system (11) within the application device, on the user side, i.e. in particular without there being any need for markings on the wound-up sealing profile or for data handling between the manufacturer of the sealing profile and the user.
B23P 19/04 - Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformationTools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
The invention relates to a method and an apparatus for fitting sealing profiles (2) on vehicle bodies or the parts thereof, wherein the sealing profile (2) is withdrawn from an unwinding unit (7) and, by way of an adhesive layer arranged on the sealing profile, is rolled on the vehicle body or the part of the vehicle body, along an application line provided for fitting purposes, by means of a pressure-exerting roller of an application head (4). The invention is based on the concept of defects and discontinuities in the sealing profile (2) being detected immediately by the arrangement of an automatic optical inspection system (11) within the application device, on the user side, i.e. in particular without there being any need for markings on the wound-up sealing profile or for data handling between the manufacturer of the sealing profile and the user.
B23P 19/04 - Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformationTools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
B25B 27/14 - Hand tools or bench devices, specially adapted for fitting together or separating parts or objects whether or not involving some deformation, not otherwise provided for for assembling objects other than by press fit or detaching same
B23P 11/02 - Connecting or disconnecting metal parts or objects by metal-working techniques, not otherwise provided for by first expanding and then shrinking or vice versa, e.g. by using pressure fluidsConnecting or disconnecting metal parts or objects by metal-working techniques, not otherwise provided for by making force fits
E06B 7/22 - Sealing arrangements on wings or parts co-operating with the wings by means of elastic edgings, e.g. elastic rubber tubesSealing arrangements on wings or parts co-operating with the wings by means of resilient edgings, e.g. felt or plush strips, resilient metal strips
A device and to a method for stacking plate-like products into a straight, cylindrical stack having an upper and a lower side and at least two side surfaces arranged at a distance from each other. In order to create a desired pretension in the stack already during stacking, which can even be maintained when individual products are added, the plate-like products are lifted against gravity from the bottom to the top into a stack nest, the products are held in the stack nest by applying a force on the side surfaces thereof to prevent dropping in the direction of gravity. While the force application is maintained, further products are added to the stack in the stack nest from the bottom side.
H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
B65G 19/24 - Attachment of impellers to traction element
B65B 61/28 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for discharging completed packages from machines
B65G 19/22 - Impellers, e.g. push-plates, scrapersGuiding means therefor
B65B 43/52 - Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up stateFeeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging positionLocating containers or receptacles at the filling positionSupporting containers or receptacles during the filling operation using roller-ways or endless conveyors
B65G 59/06 - De-stacking from the bottom of the stack
B07C 3/00 - Sorting of mail or documents according to destination
B65G 57/30 - Stacking of articles by adding to the bottom of the stack
The invention relates to a screwing tool that comprises a drive arranged in a housing and an output shaft connected to said drive, a screwdriver point being arranged at the front face of the output shaft. The aim of the invention is to provide a screwing tool with which different connecting elements, in particular actuating and clamping elements consisting of a screwable sleeve and an inner screw can be screwed with only a single screwing tool. In order to achieve this aim, the screwing tool comprises a receiving part (500) which surrounds the output shaft and is displaceably guided in the direction of the axis (202) of the output shaft (200) against the force of a return element (505). Furthermore, an annular screwing tool (400), which surrounds the output shaft (200) and the screwdriver point (201), is rotatably mounted on the receiving part (500) for detecting the drive contours (305) of the peripheral surface (304) of a connecting element (303), at least one shiftable clutch (600) being arranged between the rotatably mounted annular screwing tool (400) and the output shaft (200).
A method for attaching a sealing profile to a vehicle body part includes the steps of pulling the sealing profile from a storage unit; passing the sealing profile through a first buffer which compensates for differences between incoming and outgoing speeds of the sealing profile; attaching an adhesive strip to the sealing profile continuously, the adhesive strip having a first adhesive layer facing the sealing profile and a second adhesive layer facing away from the sealing profile; passing the sealing profile with the attached adhesive strip through a second buffer which compensates for differences between incoming and outgoing speeds of the sealing profile; and rolling the second adhesive layer onto the vehicle body part. The adhesive strip is attached to the sealing strip in an assembly unit which heats the first adhesive layer as it moves around a press roller.
The invention relates to a method for process automation, for connecting the edge of two correspondingly profiled ends of at least one profiled sealing element, said profiled sealing element being already applied to a surface of a vehicle or a vehicle component. The invention also relates to a device for carrying out said method.
B29C 65/14 - Joining of preformed partsApparatus therefor by heating, with or without pressure using wave energy or particle radiation
B29C 65/20 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool with direct contact, e.g. using "mirror"
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