Design and optimization of donor and accepter concentration profiles in a diode structure can be effective at suppressing pre-pulses appearing in high power pulses output by semiconductor opening switches that integrate the diode structure. An example diode structure includes an additional n-type region or layer that is gradually doped. For example, a diode structure includes at least three n-type regions, with the additional n-type region being sandwiched between a n-type region with relatively lower doping and a n-type region with relatively higher doping. The n-type region with relatively higher doping may also feature a doping gradient, and thus, the diode structure can include two n-type regions each having a respective doping gradient. Formation of the additional n-type region with its doping gradient at depth within the diode structure is achievable by gradual introduction of the n-type dopant during crystal growth of the diode structure.
An electrochromic device, in accordance with one embodiment, includes a substrate, an optically-active working electrode having aligned carbon nanotubes (ACNTs) coupled to the substrate, a counter electrode, and an electrolyte positioned between the working electrode and the counter electrode. An electrochromic device, in accordance with another embodiment, includes a porous membrane; an optically-active working electrode coupled to a first side of the membrane, the working electrode having aligned carbon nanotubes (ACNTs), a counter electrode coupled to a second side of the membrane that is positioned on an opposite side of the membrane as the first side, and an electrolyte positioned between the working electrode and the counter electrode.
A three-dimensional product formed by additive manufacturing, the three-dimensional product includes a plurality of continuous filaments arranged in a geometric pattern, where the plurality of continuous filaments includes a radiation-cured component and a nonradiation-cured component. A concentration of the nonradiation-cured component is in a range of greater than 5 wt % to less than 95 wt % of total weight of the three-dimensional product. The three-dimensional product includes a plurality of non-random pores located between adjacent printed continuous filaments, where an average diameter of the non-random pores is in a range of greater than 0 microns to less than 50 microns.
C09D 11/101 - Inks specially adapted for printing processes involving curing by wave energy or particle radiation, e.g. with UV-curing following the printing
B29C 64/106 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
B33Y 70/00 - Materials specially adapted for additive manufacturing
C08G 18/10 - Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
C08G 18/67 - Unsaturated compounds having active hydrogen
C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
4.
INERTIALLY ENHANCED MASS TRANSPORT USING POROUS FLOW-THROUGH ELECTRODES WITH PERIODIC LATTICE STRUCTURES
Disclosed are flow-through electrode devices and techniques for making flow-through electrodes. In one aspect, a flow through electrode apparatus comprises one or more fiber layers. Each fiber layer comprises a plurality of fibers oriented to be orthogonal to a flow direction of a fluid. The plurality of fibers are configured to cause an inertial flow of the fluid around the plurality of fibers at a first flow rate of the fluid.
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells
5.
DIVERSITY USING ADVERSARIALLY LEARNED TRANSFORMATIONS FOR DOMAIN GENERALIZATION
Arizona Board of Regents on Behalf of Arizona State University (USA)
Lawrence Livermore National Security, LLC (USA)
Inventor
Gokhale, Tejas
Anirudh, Rushil
Thiagarajan, Jayaraman
Kailkhura, Bhavya
Baral, Chitta
Yang, Yezhou
Abstract
An ALT framework (Adversarially Learned Transformations framework) may be trained to learn multiple target generalizations from a single source domain utilizing a diversity network, an adversary network, and a classifier. ALT framework may obtain an image training dataset and generate image perturbations parameterized by the adversarial network as learnable weights of a neural network representing learned image transformations by the adversarial network for the plurality of input images. Processing circuitry may train an Artificial Intelligence model (AI model) of ALT framework to learn generalizations for the single source domain from the plurality of input images of the image training dataset and the learnable weights of the neural network representing the learned image transformations by the adversarial network. Processing circuitry may train the AI model of the ALT framework to learn the multiple target generalizations from supplemental images generated by the adversarial network and output the AI model.
G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
A redox flow battery apparatus includes a membrane, a flow plate, and a porous electrode positioned between the membrane and the flow plate. The porous electrode has a surface configured for a reversible metal deposition thereon from a metal ion electrolyte solution flowing through the porous electrode. The porous electrode has a predefined porosity configured to allow the flowing of the metal ion electrolyte solution through the porous electrode.
H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells
7.
MICROGELS, LIVE CELL-LADEN MICROGELS, PRODUCTS HAVING SUCH MICROGELS, AND METHODS AND APPARATUSES FOR FABRICATING SUCH MICROGELS VIA PHOTOPOLYMERIZED IN-AIR DROP ENCAPSULATION
A live cell-laden microgel, in accordance with one aspect of the present invention, includes at least one live cell and a photocured resin. An in-air drop formed microgel, in accordance with one aspect of the present invention, includes a component selected from the group consisting of DNA, RNA, a protein, a peptide, an antibody, a living-cell produced catalyst, a nucleic acid-based material, a prokaryotic cell, an eukaryotic cell, and a different type of biological component.
A composition includes a glass-forming material and a solvent. A composition includes a glass-forming material that includes mixed composition particles and a solvent.
A product includes a three-dimensional printed structure having ligaments, where an average diameter of the ligaments is in a range of about 10 μm to about 500 μm. A method of forming a product that includes ligaments, where an average diameter of the ligaments is in a range of about 10 μm to about 500 μm, includes printing a three-dimensional structure using an ink that includes a polymer precursor, a block copolymer, a catalyst, and a solvent, immersing the printed three-dimensional structure in a second solvent for forming a gel, and drying the printed three-dimensional structure.
C08L 53/00 - Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bondsCompositions of derivatives of such polymers
C08L 61/02 - Condensation polymers of aldehydes or ketones only
10.
COMPOSITE MONOLITHIC TELESCOPES FOR APERTURE SCALING
Disclosed embodiments enable scaling of monolithic optical systems (e.g., monolith telescopes) up to larger aperture sizes while reducing mass scaling. An example optical system includes a monolithic mirror assembly that integrates a primary mirror and a tertiary mirror in static alignment. The optical system further includes a secondary mirror or fold mirror displaced away from the monolithic mirror assembly and having a reflective mirror surface. The secondary mirror's reflective mirror surface is positioned to direct light received from the primary mirror onto the tertiary mirror and direct light received from the tertiary mirror onto a detector. The secondary mirror is particularly configured to maintain a low alignment sensitivity, consistent with the permanent fixed alignment associated with the monolithic mirror assembly. For example, the secondary mirror has a relatively low power curvature and a weak fourth-order shape insensitive to decentering and tip/tilt misalignments when directing light onto the spherical tertiary mirror.
G02B 23/02 - Telescopes, e.g. binocularsPeriscopesInstruments for viewing the inside of hollow bodiesViewfindersOptical aiming or sighting devices involving prisms or mirrors
G02B 17/06 - Catoptric systems, e.g. image erecting and reversing system using mirrors only
A product, in accordance with one aspect of the present invention, includes a resin for three-dimensional printing, the resin including a photo-curable nitrile-containing photopolymer. A method for manufacturing an article of manufacture, in accordance with another aspect of the present invention, includes forming a three-dimensional (3D) structure from a photo-curable nitrile-containing photopolymer via a light-based printing process, and thermally processing the 3D structure for rendering the 3D structure electrically conductive.
C09D 133/20 - Homopolymers or copolymers of acrylonitrile
B29C 64/124 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
C08F 20/50 - Nitriles containing four or more carbon atoms
C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
C09D 133/22 - Homopolymers or copolymers of nitriles containing four or more carbon atoms
12.
PROCESSING METHOD TO CROSSLINK POLYELECTROLYTE MEMBRANES AT USER-SELECTED HYDRATION LEVEL FOR CONTROL OF NANOSCALE MORPHOLOGY
A method of forming a membrane includes forming a membrane structure that includes a material comprising a polymer, a crosslinking agent, and a solvent. The membrane structure is equilibrated at a selected relative humidity for a predefined duration of time for forming hydrophilic domains in the material. The hydrophilic domains have a predefined average radius. The equilibrated membrane structure is cured to crosslink the material to at least a predefined extent.
B01J 41/07 - Processes using organic exchangers in the weakly basic form
B01J 41/13 - Macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
B01J 47/12 - Ion-exchange processes in generalApparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes
B33Y 80/00 - Products made by additive manufacturing
C08G 65/48 - Polymers modified by chemical after-treatment
C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials
H01M 6/18 - Cells with non-aqueous electrolyte with solid electrolyte
H01M 8/1025 - Polymeric electrolyte materials characterised by the chemical structure of the main chain of the ion-conducting polymer having only carbon and oxygen, e.g. polyethers, sulfonated polyetheretherketones [S-PEEK], sulfonated polysaccharides, sulfonated celluloses or sulfonated polyesters
H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
Max-Planck-Gesellschaft Zur Foerderung Dur Wissenschaften E.V. (Germany)
The Regents of the University of California (USA)
Inventor
Noy, Alexsandr
Ho, Nga Thuy
Hummer, Gerhard
Siggel, Marc
Abstract
Disclosed herein is an engineered lipid-based vesicle optionally used for delivery of one or more payloads. The vesicle comprises a nanotube dimer or complex embedded with a lipid bilayer of the lipid-based vesicle. Also described herein are compositions, e.g., pharmaceutical compositions, and kits comprising the engineered lipid-based vesicle. In additional embodiments, further described herein are use of the engineered lipid-based vesicle for treating a disease or condition, for delivery to a target, or for labeling of a cell.
A networking architecture that incorporates the security of Blockchain distributed ledgers as an authentication layer, while connecting mesh nodes using secure, pulse-based wide-band and ultrawide-band communication technology to provide a nearly undetectable, unbreakable, and dynamic wireless communication mesh architecture that has the ability to securely transmit data, voice and video over short ranges, in one embodiment, up to 1 Km, is disclosed.
H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e.g., inhibiting) KRAS (e.g., KRAS having a G12C mutation) and treating diseases or disorders such as cancers in subjects in need thereof.
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
C07D 417/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e g., inhibiting) KRAS (e.g., KRAS having a G12C mutation) and treating diseases or disorders such as cancers in subjects in need thereof.
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
17.
METALLIC COATED GASKETS USEFUL FOR FRONT CONTACTS IN ELECTROLYSIS
A product, in accordance with one aspect of the present invention, includes a gasket comprising: a resiliently deformable electrically insulative portion, and an electrically conductive layer formed directly on the electrically insulative portion. A method for creating a product, in accordance with one aspect of the present invention, includes forming an electrically conductive layer on a resiliently deformable electrically insulative portion of a gasket via physical vapor deposition.
GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Choi, Wonjin
Cho, Changhee
Lee, Taeil
Abstract
A product includes a substrate having a plurality of kirigami cuts in a surface of the substrate, where longitudinal axes of the kirigami cuts are oriented about orthogonal to a longitudinal axis of the substrate, the plurality of kirigami cuts being arranged to allow flexure of the substrate, and a plurality of catalyst nanostructures on the surface of the substrate. The catalyst nanostructures include a photo-piezoelectric material, where the catalyst nanostructures are aligned substantially along the longitudinal axes of the kirigami cuts.
B01J 35/56 - Foraminous structures having flow-through passages or channels, e.g. grids or three-dimensional monoliths
B01J 35/40 - Catalysts, in general, characterised by their form or physical properties characterised by dimensions, e.g. grain size
B01J 23/84 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
The present disclosure relates to a projection stereolithography apparatus. The apparatus makes use of a light projector for projecting a two dimensional image into a resin vat containing a quantity of photoresponsive resin. A holder structure is provided for supporting a plurality of magnets. The holder structure supports the plurality of magnets such that the plurality of magnets are spaced at least partially around the resin vat. The plurality of magnets generate a magnetic field for controllably aligning molecules in the resin while forming a three dimensional part in a layer-by-layer process using the two dimensional image projected by the light projector.
The present disclosure relates to an energy storage medium apparatus having an electrically conductive anode having a plurality of randomly extending anode portions propagating in three dimensions, and an electrically conductive cathode having a plurality of randomly extending cathode portions propagating in three dimensions. The randomly extending anode portions and the randomly extending cathode portions are interpenetrating in three dimensions while maintaining a separation therebetween.
In one general approach, a product includes an aminopolymer having alkyl substituents coupled directly to carbon atoms in a backbone of the aminopolymer. In another general approach, a method of forming an alkyl substituted aminopolymer includes polymerizing, via ring-opening polymerization, one or more types of heterocyclic monomers thereby creating a first polymer, the one or more types of heterocyclic monomers having at least one alkyl substituent coupled directly to a carbon atom of the associated monomer; and creating, from the first polymer, an alkyl substituted aminopolymer.
The present disclosure relates to an additive manufacturing system for droplet-on-demand jetting to manufacture a part from a feedstock. In one embodiment the system comprises a printhead having a nozzle having first and second orifices for ejecting liquid droplets created from the feedstock, wherein the first and second orifices have at least one differing characteristic. A controller is provided along with a pressure pulse data file which is accessible by the controller, and which contains data needed for generating pressure pulses designed to cause ejection from one or the other of the first and second orifices of the nozzle, as needed, to form the part. A pulse generating subsystem is also included which is responsive to the controller for generating the pressure pulses relative to the nozzle, and causing ejection of liquid droplets from at least one of the first and second orifices of the nozzle.
B41J 2/045 - Ink jet characterised by the jet generation process generating single droplets or particles on demand by pressure, e.g. electromechanical transducers
In one general embodiment, a product includes an aminopolymer having alkyl substituents coupled directly to carbon atoms in a backbone of the aminopolymer. In another general embodiment, a method of forming an alkyl substituted aminopolymer includes polymerizing, via ring-opening polymerization, one or more types of heterocyclic monomers thereby creating a first polymer, the one or more types of heterocyclic monomers having at least one alkyl substituent coupled directly to a carbon atom of the associated monomer; and creating, from the first polymer, an alkyl substituted aminopolymer.
The present disclosure relates to a system for monitoring polymerization of a photo-responsive resin during an additive manufacturing operation involving manufacture of a part from the photo-responsive resin. The may have an optical system for generating a beam of light, a polarizer for polarizing the beam of light to create a linearly polarized light beam, with the linearly polarized light beam forming a first un-scattered beam after passing through a portion of the photo-responsive resin having a first refractive index, and a second scattered sample beam after passing through a second portion of the photo-responsive resin having begun a polymerization process and having a second refractive index. A spatial slight modulator receives the un-scattered beam and the scattered sample beam and controllably varies a phase of one or the other to create multiple images of the photo-responsive resin. A controller subsystem receives and combines the multiple images to create a composite image having increased contrast of the photo-responsive resin.
B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
B29C 64/124 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
B29C 64/268 - Arrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB]
B29C 64/255 - Enclosures for the building material, e.g. powder containers
H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
A product, in accordance with one aspect of the present invention, includes an aminopolymer having hydroxyl functional groups coupled directly to carbon atoms in a backbone of the aminopolymer. In another general approach, a method of forming an aminopolymer having hydroxyl functional groups coupled directly to carbon atoms in a backbone of the aminopolymer includes polymerizing a monomer having a protected hydroxyl group coupled to a carbon atom of the monomer, thereby creating a first polymer. An aminopolymer with pendant hydroxyl functionalities is created from the first polymer by, at least in part, removing hydroxyl protecting groups of the protected hydroxyl groups of the first polymer.
The present disclosure relates to an additive manufacturing system for droplet-on-demand jetting to manufacture a part from a feedstock. In one embodiment the system comprises a printhead having a nozzle having first and second orifices for ejecting liquid droplets created from the feedstock, wherein the first and second orifices have at least one differing characteristic. A controller is provided along with a pressure pulse data file which is accessible by the controller, and which contains data needed for generating pressure pulses designed to cause ejection from one or the other of the first and second orifices of the nozzle, as needed, to form the part. A pulse generating subsystem is also included which is responsive to the controller for generating the pressure pulses relative to the nozzle, and causing ejection of liquid droplets from at least one of the first and second orifices of the nozzle.
The present disclosure relates to a system for monitoring polymerization of a photo-responsive resin during an additive manufacturing operation involving manufacture of a part from the photo-responsive resin. The may have an optical system for generating a beam of light, a polarizer for polarizing the beam of light to create a linearly polarized light beam, with the linearly polarized light beam forming a first un-scattered beam after passing through a portion of the photo-responsive resin having a first refractive index, and a second scattered sample beam after passing through a second portion of the photo-responsive resin having begun a polymerization process and having a second refractive index. A spatial slight modulator receives the un-scattered beam and the scattered sample beam and controllably varies a phase of one or the other to create multiple images of the photo-responsive resin. A controller subsystem receives and combines the multiple images to create a composite image having increased contrast of the photo-responsive resin.
A product, in accordance with one aspect of the present invention, includes an aminopolymer having hydroxyl functional groups coupled directly to carbon atoms in a backbone of the aminopolymer. In another general embodiment, a method of forming an aminopolymer having hydroxyl functional groups coupled directly to carbon atoms in a backbone of the aminopolymer includes polymerizing a monomer having a protected hydroxyl group coupled to a carbon atom of the monomer, thereby creating a first polymer. An aminopolymer with pendant hydroxyl functionalities is created from the first polymer by, at least in part, removing hydroxyl protecting groups of the protected hydroxyl groups of the first polymer.
An optically addressable light valve (OALV) is disclosed which has a liquid crystal having an input side and an output side. The OALV also has a photoconductor having an input side and an output side, and a dopant providing increased damage tolerance for the photoconductor. A polarizer is also provided which is arranged downstream of the liquid crystal, relative to a travel of light through the OALV. A conductive material is also provided which is applied to the input side of the photoconductor.
G02F 1/135 - Liquid crystal cells structurally associated with a photoconducting or a ferro-electric layer, the properties of which can be optically or electrically varied
G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
30.
TITANIA-BASED DUAL FUNCTIONAL MATERIALS FOR REACTIVE CAPTURE AND CONVERSION OF CO2 TO METHANE AND OTHER PRODUCTS
This disclosure provides dual function materials (DFMs) useful in reactive carbon capture (RCC) processes with physical and chemical characteristics that provide an attractive alternative to direct air capture (DAC) and combine the steps of CO2 adsorption, extraction, and upgrading into one process, thereby eliminating the need for compression and transportation of the captured CO2. This disclosure also provides methods of making and using these DFMs.
B01D 53/73 - After-treatment of removed components
B01D 53/82 - Solid phase processes with stationary reactants
B01J 20/04 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
B01J 20/30 - Processes for preparing, regenerating or reactivating
C07C 1/12 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon from oxides of carbon from carbon dioxide with hydrogen
31.
MECHANICALLY ROBUST MULTIMATERIAL FOR ADDITIVE MANUFACTURING
A precursor resin mixture for forming a multimaterial includes a multifunctional monomer comprising two or more first functional groups bonded to a base molecule and two or more terminal functional groups having a double-bonded carbon, a multifunctional thiol monomer having one or more second functional groups positioned between terminal thiol groups, and epoxy monomer, and a curing agent. Regarding the multifunctional monomer, the terminal functional groups being different than the first functional groups.
Provided herein are compounds and compositions thereof that may be capable of disrupting, interrupting, and/or preventing an interaction between a small GTPase protein and a PI3K protein (e.g., PI3Ka). The present disclosure also provides methods of treating cancers and other indications with such compounds or compositions thereof.
Provided herein are compounds and compositions thereof that may be capable of disrupting, interrupting, and/or preventing an interaction between a small GTPase protein and a PI3K protein (e.g., PI3Ka). The present disclosure also provides methods of treating cancers and other indications with such compounds or compositions thereof.
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/4365 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61K 31/4375 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
A61K 31/438 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring being spiro-condensed with carbocyclic or heterocyclic ring systems
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/4725 - Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
A61K 31/4985 - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61K 31/502 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
A61K 31/5025 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
A61K 31/541 - Non-condensed thiazines containing further heterocyclic rings
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
In an industrial control system (ICS), latent vectors are generated to represent identity or behaviors of host devices coupled to the ICS. A computing system captures communications transmitted by a host device across a network associated with the ICS. A set of values are extracted from one or more respective fields in the communication, then applied to a trained neural network. Values of a first set of fields are applied at an input layer of the trained neural network, while values of a second set of fields are applied at an output layer of the neural network. Based on the application of the neural network to the values extracted from the communication, the computing system generates a latent vector.
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
A product includes a three-dimensional structure including a shape changing material, where the three-dimensional structure has a predefined cavity configured to function as a mold for a castable material. The three-dimensional structure is characterized as exhibiting a shape change in response to a stimulus, where the shape change is reversible. The three-dimensional structure is configured to release the castable material in response to the stimulus.
B29C 33/50 - Moulds or coresDetails thereof or accessories therefor with means for, or specially constructed to facilitate, the removal of articles, e.g. of undercut articles with means for collapsing or disassembling elastic
B29C 39/02 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor for making articles of definite length, i.e. discrete articles
B33Y 80/00 - Products made by additive manufacturing
35.
STABLE NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
Nanolipoprotein particles having at least a scaffold protein component and a membrane lipid component and related compositions, methods and systems are described. The membrane lipid component includes at least one or more membrane forming lipids, one or more polymerized lipids and/or one or more polymerizable lipids.
A61K 9/1273 - PolymersomesLiposomes with polymerisable or polymerised bilayer-forming substances
A61K 9/1278 - Post-loading, e.g. by ion or pH gradient
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A product includes a three-dimensional structure including a shape changing material, where the three-dimensional structure has a predefined cavity configured to function as a mold for a castable material. The three-dimensional structure is characterized as exhibiting a shape change in response to a stimulus, where the shape change is reversible. The three-dimensional structure is configured to release the castable material in response to the stimulus.
The present disclosure relates to an apparatus for coating rollable elements. The apparatus may have a coating subsystem for generating a coating material, and a conical, dish-like element or an array of rotating rods for supporting the rolling elements thereon for rolling motion during a coating process during which the rolling elements receive the coating material. The conical dish-like element has a plurality of spaced apart track elements for supporting the rolling elements thereon. The array of rods has a plurality of spaced apart grooves for supporting the rolling elements. The openings between track elements or rotating rods allow for particulates and/or contaminants to pass during the coating process.
C23C 14/22 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
38.
SYSTEMS AND METHODS FOR ADDITIVE MANUFACTURE EXTRUSION DIVERTER VALVE AND SENSOR ASSEMBLY
The present disclosure relates to an apparatus for extruding material to make a part using a flowable feedstock printing material. In one embodiment the apparatus makes use of a controller and a print nozzle system. The print nozzle system includes a nozzle housing for receiving the flowable feedstock material, and a nozzle element from which the flowable feedstock material is extruded. A valve system is included which communicates with the controller for controllably interrupting and restarting a flow of the flowable feed during a print operation.
Disclosed are monolithic optical systems using an aerogel molded around a mandrel. A method of manufacturing an optical system includes applying a reflective coating to at least a portion of a surface of a mandrel, placing the mandrel in a tank and subsequently filling the tank with aerogel to a predetermined depth below a top of the mandrel. The method includes adding a separation layer to the tank on top of the aerogel at the predetermined depth, catalyzing the separation layer into a solid, and adding aerogel on top of the separation layer filling the tank with aerogel above a height of the mandrel, and removing the aerogel and mandrel from the tank, drying the aerogel into a solid aerogel structure, catalyzing the reflective coating to bond the reflective coating with the aerogel, and removing the mandrel from the aerogel structure to produce the aerogel structure having a hollowed-out interior.
G02B 23/02 - Telescopes, e.g. binocularsPeriscopesInstruments for viewing the inside of hollow bodiesViewfindersOptical aiming or sighting devices involving prisms or mirrors
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
B29K 105/00 - Condition, form or state of moulded material
G02B 7/18 - Mountings, adjusting means, or light-tight connections, for optical elements for prismsMountings, adjusting means, or light-tight connections, for optical elements for mirrors
G02B 7/182 - Mountings, adjusting means, or light-tight connections, for optical elements for prismsMountings, adjusting means, or light-tight connections, for optical elements for mirrors for mirrors
G02B 7/183 - Mountings, adjusting means, or light-tight connections, for optical elements for prismsMountings, adjusting means, or light-tight connections, for optical elements for mirrors for mirrors specially adapted for very large mirrors, e.g. for astronomy
The present disclosure relates to an apparatus for extruding material to make a part using a flowable feedstock printing material. In one embodiment the apparatus makes use of a controller and a print nozzle system. The print nozzle system includes a nozzle housing for receiving the flowable feedstock material, and a nozzle element from which the flowable feedstock material is extruded. A valve system is included which communicates with the controller for controllably interrupting and restarting a flow of the flowable feed during a print operation.
An optically addressable light valve comprises a first transparent conductor layer, a layer of liquid crystal, and a photoconductor comprising an ultrawide band gap (UWBG) semiconductor. The liquid crystal is between the first transparent conductor layer and the semiconductor photoconductor. The optically addressable light valve is configured to apply a voltage across the liquid crystal and the UWBG semiconductor. A second transparent conductor may be formed in the UWBG semiconductor in some configurations, and the voltage may be applied across the first and second transparent conductor.
Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e.g., inhibiting) KRAS (e.g., KRAS having a G12C mutation) and treating diseases or disorders such as cancers in subjects in need thereof.
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
C07D 417/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
43.
PHOTOPOLYMER RESIN FORMULATION FOR FABRICATION OF SOLID SILICA GLASS STRUCTURES WITH FEATURE SIZES GREATER THAN 5 MM
A resin, in accordance with one aspect of the present invention, includes silica, one or more multifunctional monomers, a solvent for promoting dispersion of the silica in the resin, a dispersing agent, and a photoinitiator. A product, in accordance with one aspect, includes a printed glass part having cross-sectional dimensions, along (imaginary) lines in every direction intersecting a point within the printed glass part, of greater than 5 mm. A process, in accordance with one aspect, includes forming a part from a resin, the resin comprising silica, one or more multifunctional monomers, a solvent for promoting dispersion of the silica in the resin, a dispersing agent, and a photoinitiator. The one or more multifunctional monomers are polymerized to form one or more polymers during and/or after the forming. The formed part is dried. The one or more polymers are removed from the dried part. The dried part is sintered.
A resin, in accordance with one aspect of the present invention, includes silica, one or more multifunctional monomers, a solvent for promoting dispersion of the silica in the resin, a dispersing agent, and a photoinitiator. A product, in accordance with one aspect, includes a printed glass part having cross-sectional dimensions, along (imaginary) lines in every direction intersecting a point within the printed glass part, of greater than 5 mm. A process, in accordance with one aspect, includes forming a part from a resin, the resin comprising silica, one or more multifunctional monomers, a solvent for promoting dispersion of the silica in the resin, a dispersing agent, and a photoinitiator. The one or more multifunctional monomers are polymerized to form one or more polymers during and/or after the forming. The formed part is dried. The one or more polymers are removed from the dried part. The dried part is sintered.
C08K 5/12 - EstersEther-esters of cyclic polycarboxylic acids
B29C 64/129 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
In one general embodiment, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general embodiment, a resin for additive manufacturing includes molecules configured for photopolymerization and/or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt % relative to a total weight of the resin. In yet another general embodiment, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The structure has information encoded therein via the fluorophore, the information being viewable by illuminating the fluorophore with fluorescent light.
B29C 64/00 - Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
A method includes masking a carbon-containing single crystal for defining masked regions and unmasked regions on the single crystal. The method also includes performing a plasma etch for removing portions of the unmasked regions of the single crystal, thereby defining a pillar in each unmasked region, and performing a chemical etch on the pillars at a temperature between 1200° C. and 1600° C. for selectively reducing a width of each pillar.
The present disclosure relates to a system for creating parallel, near-linear features with a desired period on a surface of a workpiece, where the workpiece includes a planar substrate and a material layer formed on the planar substrate. In one embodiment the system has an etching beam generator configured to generate a processing beam, and a support structure for holding a workpiece. The workpiece is held such that an upper surface of the material layer of the workpiece is supported at an angle which is non-normal to a direction of travel of the processing beam. The angle correlates to a desired period of features to be fabricated on the upper surface of the material layer. The processing beam transforms the material layer to create generally parallel, generally linear features having the desired a period. Subsequent normal incidence etching may be used to transfer this material layer grating mask structure to the underlying substrate.
In one general aspect, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general aspect, a resin for additive manufacturing includes molecules configured for photopolymerization and/or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt% relative to a total weight of the resin. In yet another general aspect, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The structure has information encoded therein via the fluorophore, the information being viewable by illuminating the fluorophore with fluorescent light.
B29C 64/124 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
B29C 64/112 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e.g., inhibiting) KRAS (e.g., KRAS having a Q61H, G12D, G12V, G12C, G12S, G12A, G12R, or G13D mutation or wild-type KRAS, including wild-type amplified KRAS) and treating diseases or disorders such as cancers in subjects in need thereof.
C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/5517 - 1,4-Benzodiazepines, e.g. diazepam condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
A61K 31/5386 - 1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 31/5395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
50.
SYSTEMS AND METHODS FOR IMPROVED LIQUID DROPLET EJECTION FROM A GAS PRESSURIZED PRINTHEAD VIA ARBITRARY PRESSURE AND VACUUM PULSED WAVEFORMS
The present disclosure relates to a system for droplet-based printing and makes use of a controller and a printhead system. The printhead system has a housing with an internal cavity and a nozzle at a lower end thereof. The internal cavity is configured to hold a quantity of liquid feedstock material. The housing also has a feedstock infeed port for enabling a feedstock material to be fed into the internal cavity. A valve system is used which is in communication with the controller and configured to selectively pressurize the internal cavity in response to control signals received from the controller. The control signals cause operations including a vacuum to be applied to the internal cavity, as well as the internal cavity to be vented to atmosphere as well as pressurized, to thus create a pressure waveform with characteristics tailored to characteristics of the feedstock material, which causes ejection of at least one of a droplet or a material jet that controllably breaks into droplets from the nozzle.
B29C 64/112 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
B29C 64/255 - Enclosures for the building material, e.g. powder containers
A product includes a three-dimensional structure comprising a continuous metallic material. The continuous metallic material includes at least two layers. A first layer of the at least two layers includes a metal and a second layer of the at least two layers includes a transition metal having a body-centered-cubic crystal structure. A method of forming a three-dimensional structure having a continuous metallic material includes forming a polymer template, depositing a seed layer on the polymer template, and depositing a metallic layer on the seed layer. The metallic layer includes a transition metal that is nucleated by the seed layer thereby forming the continuous metallic material having a body-centered-cubic crystal structure.
Aspects of this technical solution can include transporting one or more microreactors comprising one or more polypeptides and one or more putative binding partners through a channel of an interrogation chamber, capturing data corresponding to the one or more microreactors comprising the one or more polypeptides and one or more putative binding partners in the channel, determining one or more binding affinities of the one or more polypeptides to the one or more putative binding partners based on the captured data, and generating, by a machine learning model (e.g., a neural network) receiving input based on the one or more binding affinities, output indicative of one or more predicted amino acid sequences of a polypeptide.
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
53.
UTILIZING TRACE AMOUNTS OF A SUSPECTED TARGET MOLECULE AS A CATALYST IN DETECTION REACTIONS
A method for detecting a suspected target molecule includes obtaining a reaction mixture that is not reactive at ambient temperature, the reaction mixture comprising at least two reactants, adding the suspected target molecule to the reaction mixture for causing a reaction involving the reactants in the reaction mixture, and detecting presence of a product formed from the reactants in response to the addition of the suspected target molecule. The suspected target molecule acts as a catalyst for the reaction, where the suspected target molecule includes a tertiary amine.
The Board of Trustees of the University of Illinois (USA)
Inventor
Biener, Juergen
Ye, Jianchao
Kim, Sangil
Abstract
Material processing composites, devices, methods of use, and methods of manufacturing using composites having three-dimensional interpenetrating channels separated by porous walls. Such composites include composites having a first flow channel and a second flow channel defined and separated by porous (e.g., nanoporous) walls, wherein the first flow channel and the second flow channels have a three-dimensional interpenetrating structure. The first flow channel and the second flow channel may have a triply periodic minimal surface structure, such as a gyroid or Schwartz surface structure. In some embodiments, the composite is configured for use in hemofiltration, molecular filtration, gas purification, energy storage, or chemical conversion.
B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
A61L 15/18 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
The present disclosure relates to an additive manufacturing system for building a part from a feedstock material on a build table. The system may make use of a plurality of electrodes in contact with the build table, and a current source configured to provide an electrical current, via a first subplurality of the plurality of electrodes, to the build table. A second subplurality of the plurality of electrodes is configured in contact with a surface of the build table. A voltage measuring subsystem is operably associated with the second subplurality of the plurality of electrodes and configured to measure a potential different between two points on the build table at least one of while, or after, a sintering operation is performed on the feedstock material.
Plasma and gas based optics may be used to direct light to a target that produces emission harmful to solid-state optics. In some cases, a shield having a hole, opening or separation for the light to pass may be employed to attenuate or block such harmful emission from the target thereby providing some protection for the solid-state optics. In some designs, the light incident on the target is not coaxial with light sources such as pump and/or seed sources providing beams incident on the plasma or gas based optics. In various designs, however, the plasma or gas based optic(s) is resistant to the emissions from the target.
The present disclosure relates to a method for performing an additive manufacturing operation to form a structure by processing a photopolymer resist material. A laser beam is directed at a tunable mask. At least one emergent beam is collected from a plurality of emergent beams emerging from the tunable mask. The at least one emergent beam is collimated to create a collimated beam. Each emergent beam from the tunable mask has a plurality of beamlets of varying or identical intensity, and each beamlet emerges from a unique subsection or region of the tunable mask. The collimated beam is focused into a laser beam which is projected as an image plane onto or within the photopolymer resist material, such that the same optical path length is created between the tunable mask and the focused image plane for all optical frequencies of the focused laser beam. The focused laser beam illuminates a select pattern of subsections on the tunable mask for a finite duration of time to cause simultaneous polymerization of select portions of the photopolymer resist material corresponding to the select pattern.
B29C 64/135 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask the energy source being concentrated, e.g. scanning lasers or focused light sources
B29C 64/268 - Arrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB]
B29C 64/273 - Arrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB] pulsedArrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB] frequency modulated
B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising
G03F 7/00 - Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfacesMaterials therefor, e.g. comprising photoresistsApparatus specially adapted therefor
An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.
A method of fabricating metamaterial structures without exceeding 30° C. or less in temperature comprises forming a metasurface mask by depositing a layer of nanoparticles on a surface of the substrate, etching the surface of the substrate with the nanoparticles thereon using reactive ion beam etching (RIBE), and removing at least a portion of the nanoparticles from the etched surface. Nanometer size surface features are thereby formed on the surface of a material without exceeding 30° C. in temperature, thereby forming metamaterial structures with a reduced incidence of thermal damage to the material.
A product includes a material formed above a substrate, the material comprising: a plurality of particles configured to complete a self-propagating and/or self-sustaining reaction upon initiation thereof; a solvent system; and one or more stabilizing agents. The product may include one, or multiple layers of the plurality of particles, and/or may include additional layers of a second material, which may be a non-energetic material. The particles may be configured to form a glass, an alloy, a ceramic, or a cermet upon completion of the self-propagating and/or self-sustaining reaction. The self-propagating and/or self-sustaining reaction may include an intermetallic reaction and/or a thermite reaction, may perform thermal work on the substrate, and/or may be completed in vacuum or an aqueous environment. A spatial configuration of the material, a structure in the substrate, and/or a symbol on surface(s) of the substrate may be formed upon completion of the self-propagating and/or self-sustaining reaction.
B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
C09D 11/03 - Printing inks characterised by features other than the chemical nature of the binder
63.
SYSTEMS AND METHODS FOR ELECTRICAL RESISTANCE DIAGNOSTIC FOR CONDUCTIVITY MONITORING IN LASER POWDER BED FUSION
The present disclosure relates to an additive manufacturing system for building a part from a feedstock material on a build table. The system may make use of a plurality of electrodes in contact with the build table, and a current source configured to provide an electrical current, via a first subplurality of the plurality of electrodes, to the build table. A second subplurality of the plurality of electrodes is configured in contact with a surface of the build table. A voltage measuring subsystem is operably associated with the second subplurality of the plurality of electrodes and configured to measure a potential different between two points on the build table at least one of while, or after, a sintering operation is performed on the feedstock material.
In one general approach, a heat conducting insert for a reactor includes a center portion, a cross member extending outwardly from the center portion in a radial direction, and at least two branches extending outwardly from the cross member and away from the center portion. Each of the branches has an outer portion extending laterally from a distal end of the respective branch along a portion of an imaginary semicircle. In another general approach, a heat conducting insert for a reactor includes a center portion, a cross member, an outer portion extending laterally from a distal end of the cross member along a portion of an imaginary semicircle, and at least two branches extending outwardly from the cross member from a location on the cross member located between the center portion and the outer portion, wherein distal ends of the branches extend toward, but do not extend to, the semicircle.
B01J 19/32 - Packing elements in the form of grids or built-up elements for forming a unit or module inside the apparatus for mass or heat transfer
B01J 8/02 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds
B01J 8/06 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds in tube reactorsChemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds the solid particles being arranged in tubes
C10G 2/00 - Production of liquid hydrocarbon mixtures of undefined composition from oxides of carbon
In one general approach, a heat conducting insert for a reactor includes a center portion, a cross member extending outwardly from the center portion in a radial direction, and at least two branches extending outwardly from the cross member and away from the center portion. Each of the branches has an outer portion extending laterally from a distal end of the respective branch along a portion of an imaginary semicircle. In another general approach, a heat conducting insert for a reactor includes a center portion, a cross member, an outer portion extending laterally from a distal end of the cross member along a portion of an imaginary semicircle, and at least two branches extending outwardly from the cross member from a location on the cross member located between the center portion and the outer portion, wherein distal ends of the branches extend toward, but do not extend to, the semicircle.
B01J 8/06 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds in tube reactorsChemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds the solid particles being arranged in tubes
A diffractive optical element, such as a holographic plasma lens, can be made by direction two laser beams so that they overlap in a nonlinear material, to form an interference pattern in the nonlinear material. The interference pattern can modify the index of refraction in the nonlinear material to produce the diffractive optical element. The interference pattern can modify the distribution of plasma for the nonlinear material, which can adjust the index of refraction. A third laser beam can be directed through the diffractive optical element to modify the third laser beam, such as to focus, defocus, or collimate the third laser beam.
A polyolefin-based ink for additive manufacturing includes a polyolefin comprising at least one type of functional group for crosslinking, where the polyolefin includes at least an ethylene monomeric unit and at least a propylene monomeric unit. The ethylene monomeric unit is present in a range of greater than 50 wt. % to about 75 wt. % of a total weight of the polyolefin. Moreover, the polyolefin has a molecular weight that is no more than five times the entanglement molecular weight of a homologous series of the polyolefin.
B29C 64/124 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
C09D 11/037 - Printing inks characterised by features other than the chemical nature of the binder characterised by the pigment
68.
SKIN-LAYERED POROUS SEPARATORS AND RELATED METHODS
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (USA)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (USA)
Inventor
Biener, Juergen
Huang, Sijia
Feng, Longsheng
Ye, Jianchao
Ma, Meghann Christine
Li, Donglin
Wang, Kun
Kim, Sangil
Wan, Jiandi
Abstract
A product, in accordance with one aspect of the present invention, includes a porous first layer having a first porosity, and a porous skin layer having a second porosity that is relatively lower than the first porosity. The skin layer is a self-formed layer. A method, in accordance with one aspect of the present invention, includes contacting a resin with a separator. The resin is exposed to radiation for curing the resin, thereby simultaneously creating a porous first layer and a porous skin layer positioned between the first layer and the separator. The first layer has a first porosity. The skin layer has a second porosity that is relatively lower than the first porosity.
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (USA)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (USA)
Inventor
Biener, Juergen
Huang, Sijia
Feng, Longsheng
Ye, Jianchao
Ma, Meghann, Christine
Li, Donglin
Wang, Kun
Kim, Sangil
Wan, Jiandi
Abstract
A product, in accordance with one aspect of the present invention, includes a porous first layer having a first porosity, and a porous skin layer having a second porosity that is relatively lower than the first porosity. The skin layer is a self-formed layer. A method, in accordance with one aspect of the present invention, includes contacting a resin with a separator. The resin is exposed to radiation for curing the resin, thereby simultaneously creating a porous first layer and a porous skin layer positioned between the first layer and the separator. The first layer has a first porosity. The skin layer has a second porosity that is relatively lower than the first porosity.
A newly developed generalizable screening method enables efficient identification of epitopes, in the proteomes of pathogenic agent is provided. Also disclosed are systems that enable the method as well as epitopes discovered using the method.
C40B 30/04 - Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
C40B 40/10 - Libraries containing peptides or polypeptides, or derivatives thereof
The present disclosure relates to a system for selective powder deposition (SPD) printing a part or structure. In one embodiment the system makes use of a print nozzle having a nozzle tip portion. A vibrational element is associated with the nozzle tip portion and receives an excitation signal from an excitation subsystem and generates vibrational energy which is imparted into the powder particles within the print nozzle. The vibrational element imparts the vibrational energy to the powder particles as they are deposited, which assists in compacting the powder particles.
Devices, methods and techniques related to the use of a photoconductive semiconductor switch (PCSS) to drive a high-power laser diode for a wide range of pulse widths are disclosed. In one example aspect, a circuit for driving one or more laser diodes includes an input port configured to be coupled to a voltage input, one or more inductors that are configured to be in series with the one or more laser diodes, a photoconductive switch coupled with the one or more inductors, and an output port configured to be coupled to the one or more laser diodes.
H01S 5/06 - Arrangements for controlling the laser output parameters, e.g. by operating on the active medium
H01S 5/32 - Structure or shape of the active regionMaterials used for the active region comprising PN junctions, e.g. hetero- or double- hetero-structures
Devices, methods and techniques related to the use of a photoconductive semiconductor switch (PCSS) to drive a high-power laser diode for a wide range of pulse widths are disclosed. In one example aspect, s circuit for driving one or more laser diodes includes an input port configured to be coupled to a voltage input, one or more inductors that are configured to be in series with the one or more laser diodes, a photoconductive switch coupled with the one or more inductors, and an output port configured to be coupled to the one or more laser diodes.
H01S 5/062 - Arrangements for controlling the laser output parameters, e.g. by operating on the active medium by varying the potential of the electrodes
74.
SYSTEMS AND METHODS FOR USING DIRECT INK WRITING TO MAKE A 3D ELECTROMAGNET
A system for direct ink write printing an elongated conductive element. The system may involve a controller and a print nozzle configured to extrude first and second materials. The first material may be an electrically conductive material, and the second material may be an electrical insulator. A motion control subsystem is in communication with the controller for controlling movement of the print nozzle system along a non-linear pattern in X, Y and Z axes, in a manner to encase a bead of the first material fully within the second material, to thus form the elongated conductive element.
Methods and apparatus for stochastically heating charged reactants by applying a random (stochastic) voltage signal to a working electrode, thereby inducing a stochastic electric field. By agitating the charged species in the interfacial region adjacent the working electrode or other target substrate, the stochastic electric field increases the effective temperature of the charged species while scarcely affecting any surrounding neutral molecules (e.g., water). This effect increases the reaction rates in the interfacial region and can allow the reactants to achieve rates that are commensurate with physically inaccessible temperatures in common solutions.
A vascularizing, crack sealing and/or corrosion reducing repair formulation for concrete, and corresponding methods. In one general embodiment, a repair formulation includes a casting material, and an encapsulated and/or non-encapsulated biological material in the casting material. The biological material is operative to enable concrete and/or mortar structural healing. A method for non-destructive evaluation of cementitious material, in accordance with one general embodiment, includes causing a repair formulation to vascularize along a crack in the cementitious material via a biological and/or non-biological effect, characterizing the vascularized repair formulation, and outputting a result derived from the characterization.
An ink includes a thermoplastic polymer and a solvent effective to melt the thermoplastic polymer. A method includes forming a three-dimensional (3D) structure using an ink, the ink includes a thermoplastic polymer and a solvent effective to melt the thermoplastic polymer. The method includes removing the solvent from the 3D structure, where the thermoplastic polymer remains substantially in the shape of the formed 3D structure after removal of the solvent.
Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e.g., inhibiting) KRAS (e.g., KRAS having a G12D or G12V mutation or wild-type KRAS) and treating diseases or disorders such as cancers in subjects in need thereof.
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
An ink includes a thermoplastic polymer and a solvent selected to melt the thermoplastic polymer. A method includes forming a three-dimensional (3D) structure using an ink, the ink includes a thermoplastic polymer and a solvent selected to melt the thermoplastic polymer. The method includes removing the solvent from the 3D structure, where the thermoplastic polymer remains substantially in the shape of the formed 3D structure after removal of the solvent.
C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
A product includes a mixture for converting a polyurethane where the mixture includes a functional alcohol and a catalyst. A method of converting polyurethane includes forming a mixture at an ambient temperature where the mixture includes a polyurethane, a functional alcohol, and a catalyst. The method further includes collecting a product from the mixture after a duration of time. The product includes a diallyl urethane monomer and a multi-functional alcohol.
C08J 11/24 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing hydroxyl groups
A method comprising: forming a first mask using nanoparticles of metallic material on a surface of a substrate of a component; performing a first etching operation at a first angle relative to the surface of the substrate using a nanoparticle mask to remove material from the surface to create surface features projecting from an upper surface in accordance with the nanoparticle mask; forming a second mask on the upper surface of the substrate by depositing an additional quantity of metallic material at a second angle, different from the first angle, to create a plurality of regions adjacent each one of the rods where the quantity of metallic material is absent; and performing a second etching operation at a third angle using the second mask to create a plurality of voids at each of the regions, the voids helping to form a metasurface which imparts birefringence to the component.
A product includes a mixture for converting a polyurethane where the mixture includes a functional alcohol and a catalyst. A method of converting polyurethane includes forming a mixture at an ambient temperature where the mixture includes a polyurethane, a functional alcohol, and a catalyst. The method further includes collecting a product from the mixture after a duration of time. The product includes a diallyl urethane monomer and a multi-functional alcohol.
C08J 11/24 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing hydroxyl groups
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
C08G 75/045 - Polythioethers from mercapto compounds or metallic derivatives thereof from mercapto compounds and unsaturated compounds
B29C 64/129 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
B33Y 80/00 - Products made by additive manufacturing
83.
BUILT-IN ELECTROLYZER FOR INCREASING DURABILITY OF A FLOW BATTER BY REBALANCING THE ELECTROLYTE COMPOSITION
Durability of an energy conversion and storage system is increased by rebalancing the electrolyte composition used in the system. The storage system includes a main device, a sub device, an electrolyte, and a device for directing the electrolyte from the main device to the sub device. The system has re-balancing capacity for the electrolyte properties of the electrolyte in the sub device. The as re-balancing capacity includes rebalancing pH of the electrolyte and/or rebalancing conductivity of the electrolyte and/or rebalancing solubility of the electrolyte.
Provided herein are compounds of Formula (I) and Formula (II) and compositions thereof that capable of disrupting, interrupting, and/or preventing an interaction between a small GTPase protein and a PI3K protein (e.g., PI3Kα). The present disclosure also provides methods of treating cancers and other indications with such compounds or compositions thereof. (I) (II)
C07D 237/26 - Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
Provided herein are compounds of Formula I" and Formula II and compositions thereof that are capable of disrupting, interrupting, and/or preventing an interaction between a small GTPase protein and a PI3K protein (e.g., PI3Ka). The present disclosure also provides methods of treating cancers and other indications with such compounds or compositions thereof.
C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/4365 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
A61K 31/4355 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
86.
Direct casting into droplet printed molds to create low surface finish AM parts
Various embodiments include constant pressure direct casting into molds to create low surface finish additive manufacturing parts with reduced surface roughness apparatus having a liquid metal print head, a high pressure gas supply line, a pneumatic valve between said liquid metal print head and said high pressure gas supply line, a build plate motion stage, and a stream of metal produced by said liquid metal print head that is directed onto said build plate motion stage to produce the low surface finish additive manufacturing parts with reduced surface roughness.
The present disclosure relates to an additive manufacturing system for forming a part. In one embodiment the system may make use of a controller for generating 2D pattern data for printing a part. A cathode may be used which is adapted to be disposed in a solution contained within a reservoir. The cathode is configured for facilitating electrodeposition to form a part thereon. A printhead is provided which has a plurality of microanodes forming a microanode array, and which is in communication with the controller. The printhead is disposed adjacent to the cathode and configured to receive and use the 2D pattern data to generate current signals applied to the microanodes. The microanodes cause electrodeposition of metal, using the solution, on the cathode at a plurality of select locations on the cathode, and in parallel.
Various embodiments include constant pressure direct casting into molds to create low surface finish additive manufacturing parts with reduced surface roughness apparatus having a liquid metal print head, a high pressure gas supply line, a pneumatic valve between said liquid metal print head and said high pressure gas supply line, a build plate motion stage, and a stream of metal produced by said liquid metal print head that is directed onto said build plate motion stage to produce the low surface finish additive manufacturing parts with reduced surface roughness.
The present disclosure relates to an additive manufacturing system for forming a part. In one embodiment the system may make use of a controller for generating 2D pattern data for printing a part. A cathode may be used which is adapted to be disposed in a solution contained within a reservoir. The cathode is configured for facilitating electrodeposition to form a part thereon. A printhead is provided which has a plurality of microanodes forming a microanode array, and which is in communication with the controller. The printhead is disposed adjacent to the cathode and configured to receive and use the 2D pattern data to generate current signals applied to the microanodes. The microanodes cause electrodeposition of metal, using the solution, on the cathode at a plurality of select locations on the cathode, and in parallel.
A method of electric field-enhanced impurity diffusion includes obtaining a heterostructure including a substrate of Group-III-nitride semiconductor material, a source layer including a dopant positioned directly on the substrate, and a conductive cap layer positioned above the source layer, and applying a thermal annealing treatment to the heterostructure. An electric field gradient is established within the source layer and the cap layer for causing diffusion of an element from the substrate to the cap layer, and for causing diffusion of the dopant from the source layer to a former location of the element in the substrate thereby changing a conductivity and/or magnetic characteristic of the substrate.
H01L 29/20 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only AIIIBV compounds
H01L 21/225 - Diffusion of impurity materials, e.g. doping materials, electrode materials, into, or out of, a semiconductor body, or between semiconductor regionsRedistribution of impurity materials, e.g. without introduction or removal of further dopant using diffusion into, or out of, a solid from or into a solid phase, e.g. a doped oxide layer
Iowa State University Research Foundation, Inc. (USA)
UT-Battelle, LLC (USA)
University of Tennessee Research Foundation (USA)
Eck Industries, Inc. (USA)
Lawrence Livermore National Security, LLC (USA)
Inventor
Ott, Ryan T.
Rios, Orlando
Sims, Zachary C.
Weiss, David
Kesler, Michael S.
Meng, Fanqiang
Mccall, Scott K.
Henderson, Hunter B.
Abstract
Production of a bulk Al-RE alloy body (product) using cast billets/ingots (cooling rates<100 C/s) or rapidly solidified Al-RE particulates (cooling rates 102-106° C./second) that have beneficial microstructural refinements that are further refined by subsequent consolidation to produce a consolidated bulk alloy product having excellent mechanical properties over a wide temperature range such as up to and above 230° C.
B21C 29/00 - Cooling or heating extruded work or parts of the extrusion press
B21C 29/02 - Cooling or heating extruded work or parts of the extrusion press of containers for metal to be extruded
B21C 31/00 - Control devices for metal extruding, e.g. for regulating the pressing speed or temperature of metalMeasuring devices, e.g. for temperature of metal, combined with or specially adapted for use in connection with extrusion presses
B22F 3/20 - Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sinteringApparatus specially adapted therefor by extruding
B22F 9/08 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from liquid material by casting, e.g. through sieves or in water, by atomising or spraying
C22C 1/04 - Making non-ferrous alloys by powder metallurgy
C22F 1/04 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon
An optical device provides nonlinear spectral broadening of laser pulses of a laser beam having a spatially varying intensity profile. The device comprises a nonlinear optical element and an optical path difference compensator. The nonlinear optical element has a spatially varying thickness that depends on the spatially varying intensity profile of the laser beam. The optical path difference compensator has a spatially varying thickness that varies such that the optical path length over which the laser beam propagates through the nonlinear optical element and the compensator is spatially more uniform across most of the laser beam cross-section.
The present disclosure relates to a feedstock for performing additive manufacturing through a heated extrusion print nozzle heated to a working printing temperature. The feedstock may have a glass matrix meltable at the working printing temperature and a reinforcing fiber component. The fiber reinforcing component is disposed within the glass matrix, and selected to be at least one of thermally stable or thermally oxidatively stable at the working printing temperature being used to melt the glass matrix.
C03C 14/00 - Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix
A system for autonomously determining optimal paths without collision through a travel volume for a swarm of vehicles is disclosed. The system determines a travel path for the swarm leader vehicle using a minimal cost path derived from various measures of environmental cost for avoiding objects in traveling from leader location to target location. The system also determines, for each empty neighbor location of each follower vehicle, relational costs for follower vehicle travel relative to leader vehicle travel. The various measures of relational cost seek to maintain a prescribed positional relationship between each follower vehicle and the leader vehicle given the leader vehicle travel path. Based on various measures of environmental and relational cost, the system determines the best travel path for the each follower vehicle relative to the leader vehicle.
The present disclosure relates to a multi-electrode electrochemical apparatus. In one embodiment the apparatus has a first beam-like structure having a first material coating, with the first beam-like structure forming a first electrode. A second structure is included which has a second material coating. The second structure forms a second electrode. The first and second structures are further configured in an interpenetrating fashion within a defined 3D space to form an electrochemical apparatus, and without physical contact at any point within the defined 3D space.
Provided herein are cell free protein synthesis (CFPS) systems comprising a plurality of ribosomes attached to or encapsulated within a structure, or a plurality of structures, and, optionally, a solid support. Also provided are related kits and uses of the CFPS systems. Methods of producing a protein and methods of treating a disease are provided herein.
B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
A simulation system provides real-time, flexible, and accurate simulations of radiological scenarios that can provide robust and valuable training experience to users. A radiological scenario simulation provided by a simulation system includes simulated neutron and gamma measurements provided by a neutron simulation service and a gamma simulation service, respectively. Each of the neutron simulation service and the gamma simulation service perform accelerated computational techniques to provide the simulation results to the radiological scenario simulation in real-time. In particular, the neutron simulation service performs a particle-wise simulation with an optimized number of neutron particles, scales detector objects to an increased size, and models fission behavior for a source object based on simulated neutron particles being scattered back into the source object.
A product, according to one general aspect, includes solid state electrolyte particles, each particle individually having a coating thereon, the coating comprising a first metal oxide in a first layer and a second metal oxide in a second layer. The first and second metal oxides are different. A method, according to one general aspect, includes fabricating a product using a powder of solid state electrolyte particles, each particle being coated with a coating formed via 15 cycles or less of atomic layer deposition, the coating comprising a first metal oxide in a first layer and a second metal oxide in a second layer. The first and second metal oxides are different.
C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
H01M 4/02 - Electrodes composed of, or comprising, active material
H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
A neutron activation detector comprises a first enclosure, a plurality of electrical leads, and an activation medium disposed within the enclosure. The activation medium consists substantially of a material that is activated by fast neutrons, and is arranged within the enclosure so that activation of the material by fast neutrons results in a current between the plurality of electrical leads.
A neutron activation detector comprises a first enclosure, a plurality of electrical leads, and an activation medium disposed within the enclosure. The activation medium consists substantially of a material that is activated by fast neutrons, and is arranged within the enclosure so that activation of the material by fast neutrons results in a current between the plurality of electrical leads.
patents
