Abstract

Method of dosing sterile syringes and device for use with said method Method for dosing sterile syringes with medicinal products, which comprises the steps of arranging syringes in a syringe nest and said syringe nest in a device with a cover; sterilising the syringes; loading the devices with the syringes in a dispensing system; uncovering, dosing and covering the syringes by means of a dosing system in the presence of a laminar flow, wherein said device allows the nests to be sterilised and protects the inside of the syringes from suspended particulates by means of the cover.

IPC Classes  ?

• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
• B65B 55/06 - Sterilising wrappers or receptacles prior to, or during, packaging by heat

Abstract

A method is for sterilization of flexible bags containing human plasma protein solution with electron beam. The method includes emitting at least one electron beam with energy between 400 and 500 keV. After approximately 10 nsec to 1.5 sec, a second electron beam pulse is emitted with an energy of at least 4 MeV.

IPC Classes  ?

• A61L 2/08 - Radiation
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• B65B 43/00 - Forming, feeding, opening, or setting-up containers or receptacles in association with packaging
• B65B 51/00 - Devices for, or methods of, sealing or securing package folds or closures, e.g. twisted bag necks
• B65B 55/08 - Sterilising wrappers or receptacles prior to, or during, packaging by irradiation

Abstract

Method for dosing sterile syringes with medicinal products, which comprises the steps of arranging syringes in a syringe nest and said syringe nest in a device with a cover; sterilising the syringes; loading the devices with the syringes in a dispensing system; uncovering, dosing and covering the syringes by means of a dosing system in the presence of a laminar flow, wherein said device allows the nests to be sterilised and protects the inside of the syringes from suspended particulates by means of the cover.

IPC Classes  ?

• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• A61L 2/07 - Steam
• A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
• B65B 55/06 - Sterilising wrappers or receptacles prior to, or during, packaging by heat

Abstract

A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

IPC Classes  ?

• A61L 2/08 - Radiation
• A61J 1/10 - Bag-type containers
• A61L 2/26 - Accessories
• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• B65B 55/08 - Sterilising wrappers or receptacles prior to, or during, packaging by irradiation

Abstract

An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

IPC Classes  ?

• A61L 2/08 - Radiation
• A61J 1/10 - Bag-type containers

Abstract

A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

IPC Classes  ?

• A61L 2/08 - Radiation
• A61J 1/10 - Bag-type containers
• A61L 2/26 - Accessories
• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• B65B 55/08 - Sterilising wrappers or receptacles prior to, or during, packaging by irradiation

Abstract

The invention relates to the pharmaceutical sector, in particular a device for the sterilisation of flexible bags by irradiation with an electron beam, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. The invention also relates to a method for the sterilisation of said flexible bags by irradiation with an electron beam, and to an in-line method for filling flexible bags which uses the sterilisation device and method according to the invention.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61L 2/08 - Radiation

Abstract

A method corrects the position and deviation of a syringe needle in a machine for automatically preparing intravenous medication. The machine includes an automatic actuator, together with a control system, in which are placed the syringe and a one-dimensional position sensor including a measuring plane. The correction method includes steps in which the position sensor obtains position coordinates of a first and a second point of the needle, and steps of correcting the position and deviation error of the needle, by the control system of the automatic actuator.

IPC Classes  ?

• G01B 11/00 - Measuring arrangements characterised by the use of optical techniques
• B25J 9/16 - Programme controls
• G01B 11/27 - Measuring arrangements characterised by the use of optical techniques for measuring angles or tapersMeasuring arrangements characterised by the use of optical techniques for testing the alignment of axes for testing the alignment of axes
• G01B 11/24 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• B67D 7/32 - Arrangements of safety or warning devicesMeans for preventing unauthorised delivery of liquid

Abstract

This invention relates to the pharmaceutical sector, specifically to an
improved device for electron-beam
irradiation sterilisation of flexible bags, in particular the type of flexible
bags that may contain human
plasma protein solutions for therapeutic use. This device comprises two
electron accelerators: a first
accelerator emitting an electron beam with energies between 400 and 500 keV
and a second accelerator
emitting an electron beam with an energy of at least 4 MeV. In addition, the
present invention relates to a
sterilisation method by electron-beam irradiation of such flexible bags and to
an in-line filling process for
flexible bags using the sterilisation device and method of this invention.

IPC Classes  ?

• A61L 2/12 - Microwaves
• B65B 55/08 - Sterilising wrappers or receptacles prior to, or during, packaging by irradiation

Abstract

Method for correcting the position and deviation of a syringe needle in a machine for automatically preparing intravenous medication, the machine comprising an automatic actuator, together with a control system, in which are placed the syringe and a one-dimensional position sensor comprising a measuring plane, the correction method comprising the steps in which the position sensor obtains position coordinates of a first and a second point of the needle, and steps of correcting the position and deviation error of the needle, by the control system of the automatic actuator.

IPC Classes  ?

• A61B 34/30 - Surgical robots
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61J 1/22 - Arrangements for transferring fluids, e.g. from vial to syringe with means for metering the amount of fluid
• B25J 19/02 - Sensing devices

Abstract

Method for dosing sterile syringes with medicinal products, which comprises the steps of arranging syringes in a syringe nest and said syringe nest in a device with a cover; sterilising the syringes; loading the devices with the syringes in a dispensing system; uncovering, dosing and covering the syringes by means of a dosing system in the presence of a laminar flow, wherein said device allows the nests to be sterilised and protects the inside of the syringes from suspended particulates by means of the cover.

IPC Classes  ?

• A61L 2/07 - Steam
• A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
• B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
• B65B 55/06 - Sterilising wrappers or receptacles prior to, or during, packaging by heat