The Board of Trustees of Illinois State University

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2026 February 1
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IPC Class
A01H 5/10 - Seeds 10
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells 10
A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola 9
A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms 8
A23K 20/158 - Fatty acidsFatsProducts containing oils or fats 5
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Status
Pending 3
Registered / In Force 19
Found results for  patents

1.

LOW GLUCOSINOLATE PENNYCRESS MEAL AND METHODS OF MAKING

      
Application Number 19380621
Status Pending
Filing Date 2025-11-05
First Publication Date 2026-02-26
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan

Abstract

Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.

IPC Classes  ?

  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • A01H 1/02 - Methods or apparatus for hybridisationArtificial pollination
  • A01H 5/10 - Seeds

2.

LIQUID AND SEMISOLID LUBRICANT COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF

      
Application Number 18894418
Status Pending
Filing Date 2024-09-24
First Publication Date 2025-03-27
Owner
  • UNIVERSITY OF NORTH TEXAS (USA)
  • Board of Trustees of Illinois State University (USA)
Inventor
  • Berman, Diana
  • Shirani, Asghar
  • Chapman, Kent
  • Sedbrook, John

Abstract

In one aspect, the disclosure relates to lubricant compositions comprising an oil, a wax, or a combination thereof, wherein at least one of the oil or the wax comprises a very long chain fatty acid; and wherein at least one of the oil or the wax has been modified via a transgenic route to increase a concentration of the very long chain fatty acid relative to a reference concentration of the very long chain fatty acid in the oil or the wax without the modification. In a further aspect, the VLC FA can include one or more of eicosenoic acid, erucic acid, or nervonic acid.

IPC Classes  ?

  • C10M 101/04 - Fatty oil fractions
  • C10M 113/10 - ClaysMicas
  • C10M 117/04 - Lubricating compositions characterised by the thickener being a non-macromolecular carboxylic acid or salt thereof having only one carboxyl group bound to an acyclic carbon atom, cycloaliphatic carbon atom or hydrogen containing hydroxy groups
  • C10M 123/02 - Lubricating compositions characterised by the thickener being a mixture of two or more compounds covered by more than one of the main groups , each of these compounds being essential at least one of them being a non-macromolecular compound
  • C10N 10/02 - Groups 1 or 11
  • C10N 30/02 - Pour-pointViscosity index
  • C10N 30/04 - Detergent or dispersant property
  • C10N 30/06 - OilinessFilm-strengthAnti-wearResistance to extreme pressure
  • C10N 30/12 - Inhibition of corrosion, e.g. anti-rust agents, anti-corrosives
  • C10N 30/14 - Metal deactivation
  • C10N 40/25 - Internal-combustion engines

3.

METHODS AND COMPOSITIONS FOR ALTERING SEED CHARACTERISTICS IN OILSEED PLANTS

      
Application Number US2024036935
Publication Number 2025/014824
Status In Force
Filing Date 2024-07-05
Publication Date 2025-01-16
Owner
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
  • THE BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
Inventor
  • Sedbrook, John C.
  • Marks, Michael David
  • Gautam, Barsanti
  • Brusa, Anthony

Abstract

Mutant oilseed plants that exhibit increased seed size, increased seed oil content, and/or increased seed protein content are described herein.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • A01H 5/10 - Seeds
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

4.

LOW FIBER PENNYCRESS MEAL, SEEDS, AND METHODS OF MAKING

      
Application Number 18670499
Status Pending
Filing Date 2024-05-21
First Publication Date 2024-09-26
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Esfahanian, Maliheh
  • Chopra, Ratan

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats

5.

Oilseed plants having reduced pod shatter

      
Application Number 18137263
Grant Number 12507650
Status In Force
Filing Date 2023-04-20
First Publication Date 2024-02-29
Grant Date 2025-12-30
Owner
  • Regents of the University of Minnesota (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Marks, Michael David
  • Sedbrook, John C.
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

This document relates to materials and methods for domesticating oilseed (e.g., pennycress) plants. For example, oilseed plants having reduced seedpod shatter, as well as materials and methods for making and using oilseed plants having reduced seedpod shatter are provided.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)

6.

Low glucosinolate pennycress meal and methods of making

      
Application Number 18185179
Grant Number 12484502
Status In Force
Filing Date 2023-03-16
First Publication Date 2023-08-24
Grant Date 2025-12-02
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan

Abstract

Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.

IPC Classes  ?

  • A01H 5/10 - Seeds
  • A01H 1/02 - Methods or apparatus for hybridisationArtificial pollination
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola

7.

Low fiber Pennycress meal, seeds, and methods of making

      
Application Number 18185195
Grant Number 12022848
Status In Force
Filing Date 2023-03-16
First Publication Date 2023-08-24
Grant Date 2024-07-02
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats

8.

Low fiber pennycress meal, seeds, and methods of making

      
Application Number 17643730
Grant Number 11647765
Status In Force
Filing Date 2021-12-10
First Publication Date 2022-05-19
Grant Date 2023-05-16
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats

9.

Low glucosinolate pennycress meal and methods of making

      
Application Number 17249431
Grant Number 11685927
Status In Force
Filing Date 2021-03-02
First Publication Date 2021-07-01
Grant Date 2023-06-27
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan

Abstract

Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.

IPC Classes  ?

  • A01H 5/10 - Seeds
  • A01H 1/00 - Processes for modifying genotypes
  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • A23K 40/10 - Shaping or working-up of animal feeding-stuffs by agglomerationShaping or working-up of animal feeding-stuffs by granulation, e.g. making powders
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

10.

Plants having increased oil quality

      
Application Number 16969434
Grant Number 12221612
Status In Force
Filing Date 2019-02-12
First Publication Date 2020-11-26
Grant Date 2025-02-11
Owner
  • Regents of the University of Minnesota (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Marks, Michael David
  • Chopra, Ratan
  • Folstad, Nicole
  • Wyse, Donald L.
  • Sedbrook, John C.

Abstract

This document relates to methods and materials for generating oilseed (e.g., pennycress) plants that have oil with reduced levels of polyunsaturated fatty acids (PUFAs) and/or increased levels of oleic acid. For example, oilseed plants having reduced expression levels of one or more polypeptides involved in fatty acid biosynthesis (e.g., fatty acid desaturase 2 (FAD2) and reduced oleate desaturation 1 (ROD1)), as well as methods and materials for making and using such oilseed plants are provided.

IPC Classes  ?

  • A01H 5/00 - Angiosperms, i.e. flowering plants, characterised by their plant partsAngiosperms characterised otherwise than by their botanic taxonomy
  • A01H 1/00 - Processes for modifying genotypes
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

11.

Low fiber pennycress meal, seeds, and methods of making

      
Application Number 16893636
Grant Number 11224237
Status In Force
Filing Date 2020-06-05
First Publication Date 2020-09-24
Grant Date 2022-01-18
Owner
  • Covercress Inc. (USA)
  • Board of Trustees of Illinois State University (USA)
  • Regents of the University of Minnesota (USA)
Inventor
  • Ulmasov, Tim
  • Handel, Cristine
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A01H 5/10 - Seeds
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola

12.

Plants having increased oil quality

      
Application Number 16480881
Grant Number 11396657
Status In Force
Filing Date 2018-01-26
First Publication Date 2020-04-30
Grant Date 2022-07-26
Owner
  • Regents of the University of Minnesota (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Marks, Michael David
  • Sedbrook, John C.
  • Wyse, Donald L.
  • Dorn, Kevin

Abstract

This document provides materials and methods for generating oilseed (e.g., pennycress) plants that having low levels of erucic acid. For example, oilseed plants having reduced expression levels of one or more polypeptides involved in erucic acid metabolism (e.g., fatty acid elongase 1 (FAE1)), as well as materials and methods for making and using oilseed plants having low levels of erucic acid are provided.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C12N 9/10 - Transferases (2.)
  • A01H 5/10 - Seeds
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola

13.

P-coumaroyl-CoA:monolignol transferase

      
Application Number 16540979
Grant Number 11326178
Status In Force
Filing Date 2019-08-14
First Publication Date 2019-12-26
Grant Date 2022-05-10
Owner
  • Wisconsin Alumni Research Foundation (USA)
  • Board of Trustees of Michigan State University (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Wilkerson, Curtis
  • Ralph, John
  • Withers, Saunia
  • Sedbrook, John

Abstract

The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C12N 9/10 - Transferases (2.)
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

14.

LOW GLUCOSINOLATE PENNYCRESS MEAL AND METHODS OF MAKING

      
Application Number US2019014178
Publication Number 2019/143926
Status In Force
Filing Date 2019-01-18
Publication Date 2019-07-25
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Sedbrook, John
  • Marks, Michael David
  • Mcginn, Michaela G.
  • Handel, Cristine
  • Chopra, Ratan
  • Jarvis, Brice Allen

Abstract

Thlaspi arvenseThlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.

IPC Classes  ?

  • A01H 1/06 - Processes for producing mutations, e.g. treatment with chemicals or with radiation
  • A01H 5/10 - Seeds
  • C12N 9/10 - Transferases (2.)

15.

Low glucosinolate pennycress meal and methods of making

      
Application Number 16251247
Grant Number 10988772
Status In Force
Filing Date 2019-01-18
First Publication Date 2019-07-25
Grant Date 2021-04-27
Owner
  • CoverCress Inc. (USA)
  • Board of Trustees of Illinois State University (USA)
  • Regents of the University of Minnesota (USA)
Inventor
  • Ulmasov, Tim
  • Sedbrook, John C.
  • Marks, Michael David
  • Mcginn, Michaela G.
  • Chopra, Ratan
  • Jarvis, Brice Allen

Abstract

Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.

IPC Classes  ?

  • A01H 5/10 - Seeds
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms

16.

Low fiber pennycress meal and methods of making

      
Application Number 16131633
Grant Number 10709151
Status In Force
Filing Date 2018-09-14
First Publication Date 2019-03-21
Grant Date 2020-07-14
Owner
  • COVERCRESS, INC. (USA)
  • Board of Trustees of Illinois State University (USA)
  • Regents of the University of Minnesota (USA)
Inventor
  • Ulmasov, Tim
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A01H 5/10 - Seeds

17.

LOW FIBER PENNYCRESS MEAL AND METHODS OF MAKING

      
Application Number US2018051163
Publication Number 2019/055838
Status In Force
Filing Date 2018-09-14
Publication Date 2019-03-21
Owner
  • COVERCRESS INC. (USA)
  • BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA (USA)
Inventor
  • Ulmasov, Tim
  • Handel, Cristine
  • Hartnell, Gary
  • Sedbrook, John C.
  • Marks, Michael David
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.

IPC Classes  ?

  • A23K 10/00 - Animal feeding-stuffs
  • A23K 20/00 - Accessory food factors for animal feeding-stuffs
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms

18.

Oilseed plants having reduced pod shatter

      
Application Number 16104478
Grant Number 11707029
Status In Force
Filing Date 2018-08-17
First Publication Date 2019-02-21
Grant Date 2023-07-25
Owner
  • Regents of the University of Minnesota (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Marks, Michael David
  • Sedbrook, John C.
  • Chopra, Ratan
  • Esfahanian, Maliheh

Abstract

This document relates to materials and methods for domesticating oilseed (e.g., pennycress) plants. For example, oilseed plants having reduced seedpod shatter, as well as materials and methods for making and using oilseed plants having reduced seedpod shatter are provided.

IPC Classes  ?

  • A01H 5/10 - Seeds
  • A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)

19.

P-coumaroyl-CoA:monolignol transferase

      
Application Number 14365744
Grant Number 10428342
Status In Force
Filing Date 2012-12-14
First Publication Date 2016-02-18
Grant Date 2019-10-01
Owner
  • Board of Trustees of Michigan State University (USA)
  • Wisconsin Alumni Research Foundation (USA)
  • The Board of Trustees of Illinois State University (USA)
Inventor
  • Wilkerson, Curtis
  • Ralph, John
  • Withers, Saunia
  • Sedbrook, John

Abstract

The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C12N 9/10 - Transferases (2.)
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

20.

Quaternary N-(halomethyl) ammonium salts as therapeutic agents

      
Application Number 13484233
Grant Number 09145352
Status In Force
Filing Date 2012-05-30
First Publication Date 2014-07-10
Grant Date 2015-09-29
Owner
  • UNIVERSIDAD DE CALDAS (Colombia)
  • UNIVERSIDAD DE ANTIOQUIA (Colombia)
  • THE BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
Inventor
  • Rios Vasquez, Luz Amalia
  • Ocampo Cardona, Rogelio
  • Duque, Sandra Milena
  • Robledo Restrepo, Sara Maria
  • Velez Bernal, Ivan Dario
  • Cedeño Medina, David Leonardo
  • Jones, Marjorie Ann

Abstract

Leishmania panamensis parasites, a known causative agent of leishmaniasis disease. In addition, the series of compounds are also extensive against malaria, Chagas disease, toxoplasmosis, and other parasitic diseases.

IPC Classes  ?

  • C07C 211/63 - Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
  • C07F 7/10 - Compounds having one or more C—Si linkages containing nitrogen
  • A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline

21.

QUATERNARY N-(HALOMETHYL) AMMONIUM SALTS AS THERAPEUTIC AGENTS

      
Application Number IB2013054447
Publication Number 2013/179244
Status In Force
Filing Date 2013-05-29
Publication Date 2013-12-05
Owner
  • UNIVERSIDAD DE CALDAS (Colombia)
  • THE BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
  • UNIVERSIDAD DE ANTIOQUIA (Colombia)
Inventor
  • Rios Vasquez, Luz Amalia
  • Ocampo Cardona, Rogelio
  • Duque, Sandra Milena
  • Cedeño-Medina, David Leonardo
  • Jones, Marjorie Ann
  • Velez Bernal, Ivan Dario
  • Robledo Restrepo, Sara Maria

Abstract

The use of quaternary halogenated ammonium salts for treating leishmaniasis infections and other parasitic diseases is described. Although there have been previous reports in which quaternary ammonium salts are used as antimalarial, antifungal, and antileishmanial compounds, the use of such salts containing a halogenated N-methyl substituent as a therapeutic agent against leishmaniasis had not been reported. The compounds described here, in specific those with a terminal arylalkenyl or diarylalkenyl moiety, are shown to inhibit the growth of Leishmania panamensis parasites, a known causative agent of leishmaniasis disease. In addition, the series of compounds are also extensive against malaria, Chagas disease, toxoplasmosis, and other parasitic diseases.

IPC Classes  ?

  • C07C 211/63 - Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
  • C07C 215/40 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
  • C07C 211/15 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
  • C07C 217/06 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
  • C07C 211/24 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
  • C07D 211/24 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulfur atoms by sulfur atoms to which a second hetero atom is attached
  • C07D 211/28 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
  • C07F 7/10 - Compounds having one or more C—Si linkages containing nitrogen
  • A61P 33/10 - Anthelmintics
  • A61P 33/02 - Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

22.

p-Coumaroyl-CoA:Monolignol Transferase

      
Application Number US2012069902
Publication Number 2013/090814
Status In Force
Filing Date 2012-12-14
Publication Date 2013-06-20
Owner
  • BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (USA)
  • WISCONSIN ALUMNI RESEARCH FOUNDATION (USA)
  • THE BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (USA)
Inventor
  • Wilkerson, Curtis
  • Ralph, John
  • Withers, Saunia
  • Sedbrook, John

Abstract

The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.

IPC Classes  ?

  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells