G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
H04W 4/14 - Short messaging services, e.g. short message service [SMS] or unstructured supplementary service data [USSD]
2.
MEDICAL FLUID THERAPY MACHINE INCLUDING SERVICING REGIME THEREFORE
An infusion pump for detecting an occlusion is provided. The memory stores instructions that cause the one or more processors to input data into a trained neural network, and generate an alert when the trained neural network outputs an amount of occlusion flags above a predetermined threshold.
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
4.
DYNAMIC ASSIGNMENT OF UNIQUE CAN (CONTROLLER AREA NETWORK) MESSAGE IDENTIFIERS FOR DEVICES
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
6.
MEDICAL DEVICE HUB POWER MANAGEMENT SYSTEM AND APPARATUS
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
7.
SYMMETRIC KEY EXCHANGE VIA TLS (TRANSPORT LAYER SECURITY) ON CAN (CONTROLLER AREA NETWORK) BUS INTERFACE
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A23D 7/00 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
A23D 7/01 - Other fatty acid esters, e.g. phosphatides
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
A23L 33/11 - Plant sterols or derivatives thereof, e.g. phytosterols
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
9.
AUTOMATIC SYRINGE PUMP NEAR EMPTY ALARM ACTIVATION THRESHOLD PROGRAMMING
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
10.
PCA PUMP PROGRAMMING AND PATIENT HISTORY USER INTERFACE
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
11.
SYSTEMS AND METHODS FOR CONTROLLING PARTIAL DELIVERY PUMPING IN INFUSION SYSTEMS
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
12.
HEMODYNAMIC MANAGEMENT SYSTEM, APPARATUS, AND METHODS
A hemodynamic management system, apparatus, and method are disclosed herein. An example hemodynamic management apparatus includes a display interface screen and a processor configured to access a patient medical record using a patient identifier and determine, from the patient medical record, a new infusion start event associated with an infusion pump that is fluidly connected to a patient. The processor also causes the display interface screen to display an infusion line mapping interface that shows a graphical illustration of a human body and potential access sites, prompt for selection of an access site within the infusion line mapping interface, and after receiving a selection of an access site, associate an infusion pump identifier and the selected access site. The processor also causes the display interface screen to display information from the new infusion start event in conjunction with the selected access site shown within the infusion line mapping interface.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
13.
WEARABLE HEADS-UP DISPLAY ("HUD") FOR A PHARMACY WORKFLOW MANAGEMENT SYSTEM
A wearable heads-up display ("HUD") for a pharmacy workflow management system is disclosed herein. An example HUD includes smart-glasses that are communicatively coupled to a client device. The smart-glasses include at least one camera and/ or barcode scanner to record information needed for the verification of a medication dose during medication formulation preparation. The smart-glasses include at least one microphone to record voice commands. Further, the smart-glasses include at least one embedded display screen that shows sequential steps of a preparation protocol for guiding a pharmacy technician to prepare a medication dose. An application on the client device and/or the smart-glasses is configured to recognize and use voice commands to provide navigation for the embedded display screen. The voice commands may also be used to provide data entry for medication dose preparation verification. Gestures may be detected by the camera and translated by the application into navigation or data entry commands.
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
G06Q 10/08 - Logistics, e.g. warehousing, loading or distributionInventory or stock management
G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
G06Q 10/101 - Collaborative creation, e.g. joint development of products or services
G09B 5/02 - Electrically-operated educational appliances with visual presentation of the material to be studied, e.g. using film strip
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
B01F 23/47 - Mixing liquids with liquidsEmulsifying involving high-viscosity liquids, e.g. asphalt
B01F 25/421 - Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
15.
FIBRINOGEN AND THROMBIN SOLUTIONS FOR A FIBRIN SEALANT AND FIBRIN SEALANT KIT
Disclosed are a fibrinogen solution and a thrombin solution. The fibrinogen solution comprises fibrinogen at a concen¬ tration of at least 40 mg/ml, factor XIII, pharmaceutically acceptable additives and water. The dynamic viscosity of the fibrinogen solution measured at 20°C increases at most by 35% after storing the solution at 20°C for 30 days. The thrombin solution comprises thrombin, pharmaceutically acceptable additives and water. The thrombin activity decreases at most by 15% after storing the solution at 25°C for 14 days. Also disclosed is a fibrin sealant kit with a first container comprising the fibrinogen solution and a second container comprising the thrombin solution. Further, methods for preparing a fibrin sealant and methods for treating a wound are disclosed.
A system and method for securing a pump are disclosed. The system includes a pump that contains a medicament delivery system, a processor operably coupled to the pump, a user interface in operable communication with the processor, a plurality of sensors in operable communication with the processor, and a housing. The housing includes a frame, a door, and a locking mechanism that can be selectively unlocked to allow the door to partially detach from the frame. The security system includes a swivel door assembly, which includes physical redundancies to selectively prevent access to the internal space of the swivel door assembly and a plurality of alarms. For example, in response to receiving an input from the plurality of sensors, the processor initiates at least one of the plurality of alarms to provide an indication to a user that an event has occurred.
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
17.
DETERMINATION OF OXIDIZING SUBSTANCES USING PEPTIDE DEGRADATION
An analytical method for detecting presence of oxidizing substances by measuring degradation of peptides may include preparing a test preparation that includes a peptide and a sample. The peptide degrades in the presence of oxidizing substances. The method may include detectingimpurities of the peptide in the test preparation in whichdetected impurities indicate presence of oxidizing substances in the sample. Examples include using high performance hquid chromatography to detect, identify, and quantify impurities of the peptide indicating presence of oxidizing substances in the sample. Exemplary oxidizing substances include peroxide-containing, chlorine-containing compounds, and bromine-containing compounds. Exemplary peptides include vasopressin.
A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
The present disclosure is directed to a midazolam pharmaceutical premix formulation housed in a flexible container, comprising from about 0.4 mg/ml to about 1.1 mg/ml midazolam hydrochloride and sodium chloride, wherein the formulation has a pH from about 2.7 to about 3.5. Also disclosed herein are methods of sedating a human subject in need thereof using the premix formulation.
A61K 31/5517 - 1,4-Benzodiazepines, e.g. diazepam condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
The invention provides a system for characterizing a patient including a substrate, a first electrode, a second electrode, and an electrical system. The electrical system is connected to the substrate and worn entirely on the patient's body. The electrical system in electrical contact with both the first and second electrodes and configured to inject an alternating electrical current through the first electrode and into the region of tissue. The electrical system is configured to measure a first electrical signal from the region of tissue through the second electrode. The electrical system is configured to measure a second electrical signal from the region of tissue. The first electrical signal or a signal determined therefrom indicates a resistance of the region of tissue and the second electrical signal or a signal determined therefrom indicates a reactance of the region of tissue.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
23.
INJECTION SITE WITH A MEMBRANE AND A LEAK-FREE REMOVABLE PROTECTION
A medical device for transferring a fluid from a pharmaceutical flexible container is disclosed. The medical device comprises a top part, a center part, a breakable zone between the top part and the center part and an insert part. The insert part comprises a third enclosure enclosing a second tunnel; and the top side of the third enclosure comprising a membrane, wherein a top surface of the membrane seals the third opening of the second enclosure.
A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises two first peelably sealing walls between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber, a second chamber and a third chamber, wherein the first chamber is between the second chamber and the third chamber; and at least one of the two first peelably sealing walls split into a second plurality of second peelably sealing walls and the second plurality of the second sealing walls sealed to the bottom edge to form a fourth chamber.
A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises a first peelably sealing wall and a second peelably sealing wall between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber between the first peelably sealing wall and the second peelably sealing wall, a first space between the left edge and the first peelably sealing wall, a second space between the second peelably sealing wall and the right edge; a third peelably sealing wall extending from the left edge to the first peelably sealing wall to separate the first space to form a third chamber and a fourth chamber; and a fourth peelably sealing wall extending from the right edge to the second peelably sealing wall to separate the second space to form a second chamber and a fifth chamber.
The present disclosure provides a new and innovative method for dynamically managing power and charging rates of multi-pump assemblies. In various embodiments, a computer-implemented method includes monitoring a plurality of pump parameters for a plurality of infusion pumps, assessing a change in the parameter states, establishing charging needs for each infusion pump in the plurality of infusion pumps, and establishing a charging profile for each infusion pump in the plurality of infusion pumps.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
31.
SYSTEMS AND METHODS FOR CONTROLLING PULSE MODE PUMPING IN INFUSION SYSTEMS
The present disclosure provides a new and innovative method and system for flow rate compensation in devices, such as medical devices and other electronic devices. In various embodiments, a computer-implemented method includes dispensing, by a pump controlled by a controller, a fluid from a fluid supply in a pulse mode over a period by determining a pulse volume for a pulse, determining a pulse cycle time, and for the period: controlling the position of the pump to perform a delay and perform a pulse to dispense an amount of the fluid, the pulse performed for the pulse cycle time, calculating an overshoot or undershoot of the amount of the fluid dispensed relative to the pulse volume, adjusting the pulse cycle time based on the calculated overshoot or undershoot, and repeating the dispensing until the period has elapsed.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/128 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
34.
SYSTEMS AND METHODS FOR HEAD HEIGHT PRESSURE COMPENSATION
The present disclosure provides a new and innovative method and system for flow rate compensation in devices, such as infusion pumps. In various embodiments, a computer-implemented method includes determining a location of a plurality of infusion pumps in a pump stack including the plurality of infusion pumps and a fluid supply connected to each of the plurality of infusion pumps. The computer-implemented method also includes determining a reference infusion pump, in the plurality of infusion pumps, and adjusting the flow rate for each infusion pump in the plurality of infusion pumps based on the distance between the infusion pump and the reference infusion pump.
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
35.
SYSTEMS FOR MULTI-LEVEL THERMAL MANAGEMENT OF ELECTRONIC DEVICES
The present disclosure provides a new and innovative method and system for the thermal management of devices, such as medical devices and other electronic devices. In various embodiments, a computer-implemented method includes measuring a current temperature of a device drawing power at a charge current level, identifying a current temperature threshold in a plurality of temperature thresholds based on the current temperature, the plurality of temperature thresholds including at least one rising temperature threshold and at least one falling temperature threshold, increasing the charge current level of the device when the current temperature is below a falling temperature threshold for a first period of time, and decreasing the charge current level of the device when the current temperature is above the rising temperature threshold for the first period of time.
The present disclosure relates to a terminally heat-sterilized ready-to-use parenteral nutrition formulation comprising all macronutrients and micronutrients required to meet the clinical guidelines for parenteral nutrition, wherein all said micronutrients and macronutrients are provided in one multi-chamber bag (MCB). The disclosure is also directed to a parenteral nutrition formulation comprising all such macronutrients and micronutrients. More specifically, the present disclosure is directed to a MCB comprising at least five chambers containing a carbohydrate formulation in a first chamber, an amino acid formulation in a second chamber, a lipid formulation in a third chamber, a fourth chamber comprising a vitamin formulation and a fifth chamber comprising a trace element formulation, wherein the carbohydrate formulation, amino acid formulation and/or the lipid formulation may also contain certain vitamins and certain trace elements that can be stably accommodated therein.
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
B65D 81/32 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
The invention relates to a flexible container/multi-chamber container with selective dissolved gas content for stabilizing at least one compound of a medical product having a selective gas requirement for remaining stable, comprising a solution comprising the at least one compound and a fil material from which the container is made that provides for high gas-barrier for the said gas. The at least one compound may be selenium in the form of Se(IV) and is preferably selected from the group consisting of sodium selenite, selenous acid and selenium dioxide. The selective gas may be oxygen, and the headspace of the oxygen maintains the solution to comprise dissolved oxygen (DO) at a level of 0.5 ppm to 8 ppm.
The present disclosure relates to a pharmaceutical composition for providing phosphorus to an adult or pediatric patient, wherein the composition is an aqueous solution of sodium glycerophosphate which by virtue of an improved process for producing the active pharmaceutical ingredient and the pharmaceutical composition is characterized by a low amount of free phosphate, a low amount of SGP-related substances and by a low amount of aluminum. The pharmaceutical composition is used in clinical nutrition, preferably in the preparation of nutritional formulations by compounding. The compositions can further be used for preventing or correcting phosphorus deficiency (hyperphosphatemia) in said adult or pediatric patients.
Systems and methods for detecting an occlusion in an infusion device are disclosed. One method includes generating, during an infusion session at predetermined intervals, a feature vector comprising an initial measurement of a physical force caused by fluid motion through an infusion device at the start of an infusion session, a current measurement of the physical force, a long term change in the measurement of the physical force, and a short term change in the measurement of the physical force. The feature vector is inputted, during the predetermined intervals, into a support vector machine ("SVM") to output an indication of a presence or an absence of an occlusion in the infusion device. The SVM may be trained using reference data from reference infusion sessions having known consequences regarding the presence or the absence of an occlusion at various times during the reference infusion sessions.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
42.
SYSTEM AND METHOD FOR SELF - ALIGNING HUB CONNECTOR
A system and method for self-aligning and connecting a device to a modular rack. The system includes a device comprising a connector receptacle configured to receive a connector plug, a connector seal and a bracket fixed to the device, a modular rack comprising the connector plug, a connector shell seal and a shelf configured to receive the bracket and guide the shelf in a plurality of directions. When the bracket of the device is inserted into the shelf of the modular rack, the shelf travels in the plurality of directions to self-align the connector plug of the modular rack to the connector receptacle of the device to ensure engagement of the connector plug to the connector receptacle. The connector seal is biased towards the connector shell seal to create a seal and ensure engagement of the connector plug relative to the connector receptacle.
A cartridge assembly for a filling machine includes a plurality of containers. Each container includes a volume and a stem connected to the volume. A connection line grid is in fluid communication with each stem of the plurality of containers. The connection line grid includes a first row connected to one or more containers of the plurality of containers and a second row connected to one or more containers of the plurality of containers. A filter assembly is coupled to the connection line grid.
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/12 - Methods of, or means for, filling the material into the containers or receptacles by application of pressure to material mechanically, e.g. by pistons or pumps
B65B 55/12 - Sterilising contents prior to, or during, packaging
C12M 1/32 - Inoculator or sampler multiple field or continuous type
44.
METHOD AND SYSTEM FOR PRODUCING STERILE SOLUTION FILLED CONTAINERS
A method for producing sterile solution-filled containers includes positioning a cartridge onto a filling machine. The cartridge includes a plurality of containers (26), a filter assembly (34), and a connection line 46 in fluid communication with the filter assembly. Each of the plurality of containers includes a volume and a stem in fluid communication with the volume and in fluid communication with the connection line. The method includes coupling the cartridge to a feed line in fluid communication with a mix tank, activating a pump coupled to the feed line, and at least partially filling one or more of the volumes associated with the plurality of containers by pumping fluid through the feed line, the filter assembly, and the connection line to create one or more at least partially filled containers. Further, the method includes sealing and separating each of the filled and sealed containers from the connection line.
B29C 65/00 - Joining of preformed partsApparatus therefor
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/04 - Methods of, or means for, filling the material into the containers or receptacles
B65B 3/12 - Methods of, or means for, filling the material into the containers or receptacles by application of pressure to material mechanically, e.g. by pistons or pumps
B65B 39/00 - Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
B65B 51/14 - Applying or generating heat or pressure or combinations thereof by reciprocating or oscillating members
B65B 55/12 - Sterilising contents prior to, or during, packaging
B65B 57/04 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages and operating to control, or to stop, the feed of such material, containers, or packages
B65B 61/06 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages by cutting
B65B 65/00 - Details peculiar to packaging machines and not otherwise provided forArrangements of such details
G01N 1/14 - Suction devices, e.g. pumpsEjector devices
45.
SYSTEM AND METHOD FOR GENERATING BATTERY ALARMS IN INFUSION DEVICES
A system and method is disclosed for detecting remaining battery voltage or capacity in an infusion device and generating alarms based on the detection. The battery lifetime extension method includes providing an infusion device that derives its power from a rechargeable battery. The infusion device may derive its power from a rechargeable battery. Furthermore, the infusion device receives, at predetermined intervals of time in real-time sensor data comprising: a voltage, a change in the voltage over the predetermined interval of time, an average current, a temperature, and a remaining voltage or capacity reported by a battery gas gauge integrated circuit ("IC") associated with the rechargeable battery. An improved and customized neural network model utilizes the sensor data to determine an indicia of the actual remaining voltage or capacity of the rechargeable battery in real-time. The indicia may be used to lengthen and/or abate ongoing medical infusion therapy.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
G01R 31/3842 - Arrangements for monitoring battery or accumulator variables, e.g. SoC combining voltage and current measurements
A composition for use in the treatment of a patient suffering from or being at risk of developing a gastrointestinal disorder is disclosed. The composition is an aqueous solution for injection comprising arginine butyrate in a concentration of from 150 mg/L to 5500 mg/L of the composition. A method of treating a patient suffering from or being at risk of developing a gastrointestinal disorder by administering the related compositions is also disclosed.
A method for extending the storage lifetime of a battery located in a device is disclosed. The battery lifetime extension method includes providing a device that derives its power from a rechargeable battery. The method further includes providing a rechargeable battery that is capable of communicating with the device. When the device is powered off by a user, a computer implemented program utilized by the device communicates with the battery and automatically powers up the device into a lower power mode upon expiration of a variable duration timer monitored by the computing unit that continuously repeats according to the programed duration cycle, evaluates the state of charge of the rechargeable battery, determines whether the state of charge of the rechargeable battery is above or below a variable programed threshold, and communicates a command to the rechargeable battery to remain in a low power state until a charge is applied to the rechargeable battery.
The invention relates to a medical product for preventing or correcting vitamin A deficiency in a patient comprising a lipid emulsion in a flexible container, the lipid emulsion comprising (a) vitamin A in the lipid phase of the lipid emulsion, (b) optionally additionally vitamin D, vitamin E and/or vitamin K in the lipid phase of the lipid emulsion, and (c) no more than 1.5 ppm dissolved oxygen (DO), (d) wherein the pH of the lipid emulsion is from 5 to 9.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
The invention relates to a terminally heat-sterilized multi-chamber container for parenteral nutrition, comprising a first chamber containing a macronutrient formulation and a second chamber comprising a vitamin B12 formulation, wherein the vitamin B12 formulation (a) is essentially free from glucose, amino acids, vitamin B1, ascorbyl palmitate and/or vitamin C; and (b) stably comprises vitamin B12 for at least 6 months at a temperature of from 1°C to 40°C and/or for at least 24 months at a temperature of 25°C.
A61K 31/455 - Nicotinic acid, i.e. niacinDerivatives thereof, e.g. esters, amides
A61K 31/525 - Isoalloxazines, e.g. riboflavins, vitamin B2
A61K 31/714 - Cobalamins, e.g. cyanocobalamin, vitamin B12
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61P 43/00 - Drugs for specific purposes, not provided for in groups
50.
HANDHELD GAS SPRAY SYSTEM FOR MIXING AND DISPENSING MULTI-COMPONENT COMPOSITIONS
Handheld gas spray systems for mixing and dispensing multi- component compositions. The system comprises a fluid conveyance subassembly in fluid communication with a syringe, wherein the syringe houses at least two different sealant components. The system comprises further a housing, a gas cartridge disposed inside the housing and a gas valve assembly disposed inside the housing, wherein the gas valve assembly is configured to control flow of gas from the gas cartridge to the fluid conveyance subassembly. A trigger is configured to actuate the gas valve assembly and a detachable spray tip is configured to dispense the multi-component fluid out of the applicator.
A61B 17/00 - Surgical instruments, devices or methods
B05B 11/06 - Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
B05B 12/00 - Arrangements for controlling deliveryArrangements for controlling the spray area
B05C 17/005 - Hand tools or apparatus using hand-held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material through an outlet orifice by pressure
51.
IV DRESSING WITH EMBEDDED SENSORS FOR MEASURING FLUID INFILTRATION AND PHYSIOLOGICAL PARAMETERS
The invention provides an intravenous (IV) dressing system that helps secure an IV catheter to a patient while simultaneously using embedded peripheral venous pressure (PVP), impedance, temperature, optical, and motion sensors to characterize properties of the IV system (e.g., infiltration, extravasation, occlusion) and the patient's physiological parameters (e.g., heart rate, SpO2, respiration rate, temperature, and blood pressure). Notably, the system converts PVP waveforms into arterial BP values (e.g., systolic and diastolic blood pressure).
The invention provides an IV system for monitoring a patient that is positioned on the patient's body. The IV system includes: 1) a catheter that inserts into the patient's venous system; 2) a pressure sensor connected to the catheter that measures physiological signals indicating a pressure in the patient's venous system; 3) a motion sensor that measures motion signals; and 4) a processing system that: i) receives the physiological signals from the pressure sensor; ii) receives the motion signals from the motion sensor; iii) processes the motion signals by comparing them to a pre-determined threshold value to determine when the patient has a relatively low degree of motion; and iv) process the physiological signals to determine a physiological parameter when the processing system determines that the motion signals are below the pre-determined threshold value.
The present disclosure relates to parenteral nutrition formulations, including ready-to-use parenteral nutrition formulations which are reconstituted from multi-chamber containers and amino acid formulations. More particularly, the present disclosure is directed to formulations comprising butyrate derivatives, specifically arginine butyrate, for use with adult or pediatric patients. The disclosure further provides for methods of reducing or preventing systemic and local inflammation of patients receiving parenteral nutrition, and methods of maintaining or ameliorating their systemic immunity and local immunity, as well as the patients´ gut barrier functions.
An infusion pump includes a housing, a pumping mechanism, an accelerometer configured to detect at least one of pump motion and pump angular orientation, and a temperature control unit. The temperature control unit is configured to receive accelerometer data and determine a pump configuration based on the accelerometer data. The pump configuration may include a contact configuration or a non-contact configuration. The temperature control unit is also configured to establish a threshold housing temperature based on the determined pump configuration. Additionally, the temperature control unit is configured to modify at least one pump feature or function to maintain the housing below the threshold housing temperature.
An infusion pumping mechanism includes a motor, a plurality of pump fingers and an opposing plate. Each finger of the pump fingers includes a body portion and a head portion. The head portion includes a tip that is configured to contact and occlude a tube installed in the pumping mechanism. The opposing plate includes an anvil with a plurality of force concentrators. A force concentrator of the plurality of force concentrators corresponds to a respective pump finger of the plurality of pump fingers. Additionally, the force concentrator includes a concentration surface configured to contact and occlude the tube. The force concentrator is aligned with a tip of the respective pump finger such that as the finger is directed towards the tube and contacts the tube, both the tip and the force concentrator provide pressure to opposite sides of the tube and at least partially occlude the tube.
A system includes a server including a clock and a plurality of medical devices in network communication with the server. Each medical device includes at least one alarm mechanism and an internal clock. A first medical device of the plurality of medical devices is configured to receive a clock synchronization data from the server, update the internal clock of the first medical device based on the clock synchronization data, provide an alarm signal of a first type at a first time, and provide a subsequent alarm signal of the first type at a second time. The second time occurs at a predetermined interval from the first time. Additionally, the second time is the same time the alarm signal of the first type is provided by a second medical device of the plurality of medical device.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
57.
DIGITAL COMMUNICATION MODULE FOR TRANSMISSION OF DATA FROM A MEDICAL DEVICE
A digital communication module for transmission of data from a medical device is disclosed. In an example, a digital communication apparatus includes an input interface configured for communicative coupling to a medical device and an output interface configured for communicative coupling to a medical network. A processor of the digital communication apparatus receives a configuration file that specifies one input port of the input interface and at least one output port of the output interface, a first data format, and a second data format. The processor installs drivers for the input and output ports specified by the configuration file, provisions the input interface with the specified input port to receive medical data from the medical device in the first data format, and provisions the output interface with the at least one specified output port to transmit the received medical data using the first data format and the second data format.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
58.
DAPTOMYCIN FORMULATIONS CONTAINING A COMBINATION OF SORBITOL AND MANNITOL
In an aspect, a method of manufacture of a pharmaceutically acceptable solid composition containing daptomycin includes drying an aqueous solution containing (i) water, (ii) the daptomycin, (iii) sorbitol in an amount of about 1.2 wt.% to about 9.0 wt.% of total volume of the aqueous composition and (iv) mannitol in an amount of about 0.6 wt.% to about 9.5 wt.% of total volume of the aqueous composition to form the solid composition. The drying can include an sublimation drying of about -25 °C to about 50 °C for a time period of about 15 hours to about 120 hours, most preferably about 15 °C for about 20 hours, optionally preceded and/or followed by one or more additional drying steps. Other aspects are the solid composition containing the daptomycin and also methods of treating a bacterial infection including administering a pharmaceutically acceptable product made by reconstituting the solid composition.
A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
A vascular monitoring system includes a collar configured to be positioned about a patient's vessel and a transducer coupled to the collar. The collar may be formed by a strap that is wrapped around the patient's vessel and maintained in a closed configuration. The transducer is configured to emit an ultrasonic signal that is transmitted through the patient's vessel.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
61.
STABILIZATION OF SELENITE IN A NUTRITIONAL SOLUTION BY DISSOLVED OXYGEN
The invention relates to a medical product for preventing or correcting selenium deficiency in a patient comprising a solution provided in a flexible container comprising at least one selenium compound in the form of Se (IV), which is preferably selected from the group consisting of sodium selenite, selenous acid and selenium dioxide, characterized in that the solution comprises dissolved oxygen (DO), preferably 0.5 ppm to 8 ppm DO.
The invention relates to a medical product for preventing or correcting selenium deficiency in a patient comprising a solution provided in a flexible container characterized in that the solution comprises at least one of a selenate salt and/or a seleno-amino acid, such as selenomethionine or selenocysteine.
The present disclosure relates to a sterile medical product for parenteral nutrition comprising a polymeric container having at least a first and a second chamber which are separated by a non-permanent peel seal, wherein the first chamber contains a composition of amino acids and optional- ly electrolytes, and wherein the second chamber contains a dextrose solution, and wherein the product is characterized by a high protein (nitrogen) content per volume. The reconstituted solution is configured to be administered periph- erally or centrally for the treatment of patients suffering from malnutrition and/or having a need for increased uptake of amino acids.
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
A device for transmitting and sensing signals comprises a non-conductive substrate adherable to a skin of a subject, two or more electrical contacts printed on the substrate, and a disposable connector, connectable to a compatible cable connector of a cable which receives signals from the contacts via the disposable connector. The disposable connector has a symmetric shape such that mating between the disposable connector and the compatible cable connector is established at either one of two flipped orientations.
A kit for transmitting and sensing signals comprises: a multi-connection cable having a plurality of cable connectors at a distal end of the cable for establishing electrical communication between each of the cable connectors and a system for measuring bioimpedance that is connectable to a proximal end of the cable, and a plurality of devices for transmitting and sensing signals. Each device comprises a non-conductive substrate adherable to a skin of a subject, a first and a second electrical contacts printed on the substrate, and a disposable connector. Each disposable connector is connectable to a compatible cable connector of the cable in a manner that a combined thickness of the disposable connector and the compatible cable connector, once connected, is less than 4 mm.
A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
A61B 5/053 - Measuring electrical impedance or conductance of a portion of the body
A body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient featuring a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
Infusion pump alignment features for vertically-oriented IV tubes are disclosed. In an example, an infusion pump housing (312) includes a tube channel (404) having a radial curvature for bending an IV tube (301) from a horizontal orientation to a vertical orientation when the infusion pump (300) is positioned for operation. The housing also includes a hood (402) having a first side and a second side that are divided by the tube channel. The infusion pump has a door (304) that is connected to the housing for enclosing the tube channel and the hood. The door includes a cavity having dimensions to receive the hood when the door is in a closed position. The hood is configured to engage the cavity to prevent the door from closing if the IV tube is not positioned along the tube channel.
A pharmaceutically acceptable insulin premix formulation contains about 0.1-10.0 Unit/mL of insulin for intravenous administration and preferably further contains a tonicity adjuster, and may be aseptically filled into a flexible container assembly to form a pharmaceutical insulin premix product, which can be a sterile and ready-to-use aqueous solution for glycemic control in an individual with metabolic disorders through intravenous infusion. The insulin premix product is unexpectedly stable when freshly prepared and also during its shelf-life of storage at refrigeration temperatures of 2 ºC to 5 ºC for 24 months followed by additional 30 days at room temperatures of 23 ºC to 27 ºC, even without any added preservative, any added zinc, any added surfactant or any other added stabilizing excipient.
A Doppler blood flow monitoring device (150) includes a signal generation module, a signal reception module, a signal filtration module, a signal conversion module, at least one speaker, and a user interface (304). The signal generation module is configured to send a signal to a probe (106) positioned in a probe receptacle on a vascular coupler positioned about a patient's vessel. The signal reception module is configured to receive a return signal from the probe. The signal filtration module is configured to filter the return signal. The signal conversion module is configured to convert the filtered signal into an audible indication and a visual indication corresponding to a characteristic of blood flow in the patient's vessel. The at least one speaker (214) is configured to emit the first audible indication. Additionally, the user interface is configured to display the visual indication.
A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
A graph database for outbreak tracking and management is disclosed. In an example embodiment, an outbreak management system includes a memory device storing instructions that define a graph database for disease outbreak tracking. The instructions specify for a given host that a host node is created and an episode node is connected to the host node via a 'case' link. The episode node is associated with episode parameters that are related to a disease classification of the host. In addition, the instructions specify that an outbreak node is connected to the episode node via a 'part of' link to indicate that the host has become part of an outbreak of the disease. The outbreak node is connected to a definition node via a 'defined as' link. The definition node specifies disease parameters of the disease that is related to the outbreak node.
G16H 50/80 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for detecting, monitoring or modelling epidemics or pandemics, e.g. flu
72.
LIPID EMULSION FOR PARENTERAL NUTRITION COMPRISING GPC
The present disclosure relates to parenteral nutritional formulations, including ready-to-use parenteral nutrition formulations. More particularly, the present disclosure is directed to lipid formulations or emulsions and multi-chamber containers comprising same, wherein the lipid emulsion contains glycerophosphorylcholine as a choline source. The present disclosure further relates to methods of providing choline to a patient in need of parenteral nutrition and methods of avoiding and/or treating choline deficiency and liver damage.
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
A23L 33/11 - Plant sterols or derivatives thereof, e.g. phytosterols
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Parenteral nutrition formulations for pediatric patients are disclosed. The nutritional formulations include a lipid formulation that comprises an aqueous phase and an oil phase, wherein the lipid formulation is in the form of an oil-in-water emulsion. Multi-chamber containers for parenteral nutrition administration comprising a carbohydrate formulation present in a first chamber, an amino acid formulation present in a second chamber, and the lipid formulation present in a third chamber also are disclosed.
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
An infusion pump includes a housing with a door pivotally mounted to the housing, a tube channel on the housing configured to hold a tube in the infusion pump, a pumping mechanism including a shuttle, and a slide clamp ejection device.
A syringe pump includes a housing with a syringe accepting region, a syringe holding system configured to hold a syringe in the syringe accepting region, a drive mechanism, and a drive head operatively coupled to the drive mechanism. The drive head is configured to engage a piston of a syringe held by the syringe holding system.
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
76.
MEDICAL DEVICE DATA BACK-ASSOCIATION, SYSTEM, APPARATUSES, AND METHODS
A medical device data back-association system, apparatuses, and methods are disclosed. In an example embodiment, a server receives first medical device data from a medical device including a device identifier and stores the first medical device data to an unassociated record in a database after determining that there is no association between the device identifier and any patient identifier or medication order identifier. While the medical device is administering the medication to a patient, the server receives an identifier message including at least two of the device identifier, the patient identifier, and the medication order identifier. The server creates an identifier association between a medical record of the patient and the medical device using the identifier message. The server uses the identifier association to store subsequent medical device data from the medical device to the medical record of the patient.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
77.
PARENTERAL NUTRITION DIAGNOSTIC SYSTEM, APPARATUS, AND METHOD
A parenteral nutritional diagnostic system, apparatus, and method are disclosed. In an example embodiment, a parenteral nutritional diagnostic apparatus determines muscle quantity and muscle quality of a patient's psoas muscle to determine a nutritional status of the patient. An image interface is configured to receive a medical image including radiodensity data related to imaged tissue of the patient. The apparatus also includes a processor configured to use the medical image to determine a tissue surface area for each different value of radiodensity and determine a distribution of the tissue surface area for each radiodensity value. The processor is configured to determine muscle quality by locating a soft tissue peak within the distribution that corresponds to a local peak in at a region related to at least one of muscle tissue, organ tissue, and intramuscular adipose tissue. The processor determines the nutritional status of the patient based on soft tissue peak.
A61J 15/00 - Feeding-tubes for therapeutic purposes
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
(57) Abstract: An assembly for mixing and dispensing a multi-component fluid includes a sheath having first and second fluid cham¬ bers, a chamber coupler, and a flexible tip. The chamber coupler forms first and second fluid channels. Additionally, the flexible tip forms a mixing chamber with a variable mixing volume and an outlet. The flexible tip is coupled to the chamber coupler near a distal end of the sheath. In the presence of an activation force, the flexible tip is forced out of the sheath and positioned in a dispensing state with a maximum mixing volume. In the absence of the activation force, the flexible tip is housed within the sheath and positioned in a non-dispensing state with a minimum mixing volume such that the outlet is substantially closed.
B65D 81/32 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
79.
VOLUME-BASED FLOW RATE COMPENSATION TECHNIQUE FOR INFUSION THERAPY
An infusion pump is provided for pumping fluid through an administrative set at a desired flow rate over a specified duration, and includes a pumping mechanism for releasably receiving and for exerting a pulsing force on the administrative set, thus pressurizing a portion of the set for creating a flow of fluid from a set outlet. A controller is connected to and is configured for operating the pumping mechanism, the controller determines a pulse frequency based on a volume of fluid infused over a portion of the specified duration and the desired flow rate, outputs a control signal to the pumping mechanism for operating the pumping mechanism based on the determined pulse frequency, determines a first pulse frequency based on the desired flow rate; and adjusts the first pulse frequency based on the volume of fluid infused to provide a second pulse frequency being different from the first pulse frequency.
An infusion pump for delivering an intravenous ("IV") fluid includes a housing comprising an actuation area that engages a portion of an IV tube. The actuation area includes a first end that receives the IV tube from a fluid container and a second end that provides the IV tube to a patient. The housing also includes a seal section located along a perimeter of at least a portion of the actuation area. The seal section includes a gasket rib positioned along the seal section and a tube channel configured to cradle the IV tube. The example infusion pump also includes a door connected to the housing and configured to engage the gasket rib to enclose the actuation area of the housing.
An infusion pump (100) includes a housing (110). The housing includes a tube port (150) adapted to receive an intravenous ("IV") tube (120). The tube port includes a tube channel (240) and a rib (280). The tube channel has an inlet and an outlet end. The rib is positioned along the channel adjacent the outlet end. The rib is formed to extend towards the tube when the tube is passed through the tube port thereby indenting the tube and tending to prevent full occlusion of the tube. The tube port may also include a plurality of ribs positioned around a perimeter of the tube port on the exterior side of the housing. The plurality of ribs are configured to prevent an occlusion in the tube when the tube is bent on the exterior side of the housing.
Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and cardiac and respiratory rates, and patient respiratory volume or effort.
A welding apparatus (100) for use in welding first (102a) and second (102b) sheets of material together includes a seal die (110), a platen (120), a control unit (130), and a power source (140) adapted to provide energy to the seal die (110). The seal die (110) is made of a conductive material and is configured to impart thermal-mechanical energy to the first (102a) and second (102b) sheets of material. The seal die (110) includes a bottom surface (310) configured to contact the first sheet (102a), an inner edge (320), a chamfer (330) extending between the bottom surface (310) and the inner edge (320), a first blend radius (340), and a second blend radius (350). The first radius (340) extends between the chamfer (330) and the bottom surface (310), while the second radius (350) extends between the chamfer (330) and the inner edge (320). The platen (120) is configured to support the second sheet (102b), while the control unit (130) is programmed to cause the seal die (110) to be directed towards the platen (120).
The present disclosure provides methods of improving adhesion of a non-di-(2- ethylhexyl)phthalate (DEHP) plasticized polyvinyl chloride (PVC) to an acrylic-based polymer or an ABS-based polymer. Such methods may comprise blending the acrylic-based polymer or ABS-based polymer with an impact modifier so that a rubber content in the acrylic-based polymer or ABS-based polymer is greater than 12% (w/w). Also provided are components of a device (e.g., a medical device) made by the disclosed methods.
A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.
ABSTRACT A method of providing filled product bags of sterile fluid using a machine comprises loading a product bag onto a loaded cradle of a plurality of movable cradles carried by a carousel, the loaded cradle occupying a loading position, the product bag including a bladder, a stem fluidly connected to an opening of the bladder, and a filter disposed in-line with the stem; moving the loaded cradle and the product bag to a filling station that includes a nozzle by rotating the carousel and moving the loaded cradle from the loading position to a filling position adjacent the nozzle; connecting an inlet of the stem to the nozzle by moving the loaded cradle and the product bag toward the nozzle; and at least partially filling the product bag with a fluid dispensed through the nozzle to create a filled product bag. Date Recue/Date Received 2020-10-27
A61J 3/00 - Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 31/02 - Filling, closing, or filling and closing, containers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
B65B 43/60 - Means for supporting containers or receptacles during the filling operation rotatable
87.
METHOD AND MACHINE FOR PRODUCING STERILE SOLUTION PRODUCT BAGS
A method of providing filled product bags of sterile and particulate-free fluid includes securing a product bag to one of a plurality of movable cradles, wherein the product bag has a bladder, a stem fluidly connected to an opening of the bladder, and a filter disposed in-line with the stem. After securing the bag, an inlet of the stem is connected to an outlet of a nozzle assembly and at least partially filling the product bag with a fluid through a nozzle of the nozzle assembly to create a filled product bag, wherein filling the product bag includes passing the fluid through the filter and into the bladder. After filling, the stem of the filled product bag is sealed at a location below the filter. The stem is cut at a location above the seal and below the filter. The method including performing an integrity test on the filter, removing the filled product bag from the cradle, and depositing the filled product bag into a first bin for rejected bags if the filter fails the integrity test and a second bin for accepted bags if filter passes the integrity test.
A61J 3/00 - Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 31/02 - Filling, closing, or filling and closing, containers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
B65B 43/60 - Means for supporting containers or receptacles during the filling operation rotatable
88.
MEDICAL DEVICE DATA INTEGRATION APPARATUS AND METHODS
Methods, systems, and apparat¬ uses integrating medical device data are disclosed. In an example embodiment, a vital sign monitor apparatus includes a renal failure therapy interface configured to receive a renal failure therapy parameter from a renal failure therapy machine performing a renal therapy treatment on a patient and an infusion pump interface configured to receive an infusion parameter from an infusion pump performing an infusion treatment for the same patient. The apparatus also includes a vital sign monitor engine configured to display, within a combination user interface of a vital sign monitor, the renal failure therapy parameter within a renal failure therapy timeline, and the infusion parameter within an infusion timeline that is aligned with the renal failure therapy timeline.
An integration engine apparatus comprises: a configuration interface configured to receive an identifier of a patient; a subscription processor configured to: transmit a first message, including the patient identifier, to a first gateway to receive infusion therapy progress data from at least one infusion pump, and transmit a second message, including the patient identifier, to a second gateway to receive renal failure therapy progress data from at least one renal failure therapy machine; and a data processor configured to: cause a first interface to receive the infusion therapy progress data from the first gateway, cause a second interface to receive the renal failure therapy progress data from the second gateway, and cause a combination user interface to display the infusion therapy progress data within an infusion timeline and the renal failure therapy progress data within a renal failure therapy timeline that is aligned with the renal failure therapy timeline.
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
90.
OPTICAL IMAGING ASSEMBLY AND SYSTEM WITH OPTICAL DISTORTION CORRECTION
An optical imaging assembly is provided, having an optical axis, an object axis, a light-transmissive sleeve enclosing the object axis, being telecentric in object space, having at least three refractive lens elements, at least one of said elements having surfaces having at least one of cylindrical and acylindrical prescription, with an image plane, wherein the object being imaged lies within the sleeve.
A drip chamber (102, 202, 302) for an infusion tube, including: a first end (104, 204, 304) arranged to receive a drip tube (106, 206, 306); a second end (108, 208, 308) including an exit port (110, 210); at least one wall (112, 212, 312) connecting the first and second ends; a space (120, 220, 320) enclosed by the first and second ends and the at least one wall; and at least one lens (121, 221, 321) integral to the at least one wall or directly fixed to the at least one wall.
A drip chamber for an infusion tube, including: a first end (106) including a drip tube (108); a second end (110) including an exit port (112); and a wall (114) connecting the first and second ends and including an interior surface (116) with a hydrophobic portion (118). The drip chamber includes a space (122) enclosed by the interior wall and the first and second ends. The hydrophobic portion (118) of the interior surface repels liquid contacting the hydrophobic coating. The hydrophobic portion of the interior surface enables light to refract through the hydrophobic portion and the wall in the same manner as is the case when the hydrophobic portion is not present on the interior surface.
An optical imaging system for use with an infusion tube including: at least one light source for emitting at least two of first, second, or third spectrums of light; an optics system including a single lens for receiving and transmitting at least two of the first spectrum light transmitted through a first portion of the chamber, the second spectrum light transmitted through a second portion of the chamber, or the third spectrum light transmitted through a third portion of the chamber. The system includes a sensor receiving the at least two of the spectrums from the lens and generating and transmitting data characterizing the at least two of the spectrums. The system includes a memory element storing computer readable instructions and a processor to execute the instructions to generate, using the data, at least two of first, second, or third images of the first, second, and third portions, respectively.
An infusion line management system is provided, including a label generating device receiving prescription information for one or more patient prescriptions, the received information being used to generate, for each of the one or more prescriptions, a label including a master label and one or more sub-labels related to the corresponding prescription; each master label includes at least information related to the prescription and an indicator identifying a particular portion of a patient infusion system to which the prescription should be connected; and the one or more sub-labels each include the indicator, the one or more sub-labels being individually removable from the master label and affixable to locations throughout the patient infusion system.
A61B 90/90 - Identification means for patients or instruments, e.g. tags
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
The invention discloses a hemostatic composition comprising crosslinked gelatin in particulate form suitable for use in hemostasis, wherein the composition is present in paste form containing 15.0 to 19.5% (w/w), preferably 16.0 to 19.5% (w/w), 16.5 to 19.5% (w/w), 7.0 to 18.5% (w/w)or 17.5 to 18.5% (w/w),more preferred 16.5 to 19.0% (w/w)or16.8 to 7.8% (w/w), especially preferred 16.5 to 17.5% (w/w), and wherein the composition comprises an extrusion enhancer.
The invention discloses a hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, and b) one hydrophilic polymeric component comprising reactive groups.
The invention discloses a hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, and b) one hydrophilic polymeric component comprising reactive groups.
The invention discloses a hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, and b) one hydrophilic polymeric component comprising reactive groups.
An infusion pump, including: a specially programmed microprocessor; a drip chamber for connection to a source of fluid and to an output tubing; a pumping section including a plurality of fingers and a first actuator, controllable using the microprocessor, for sequentially displacing the plurality of finger to compress a first portion of the output tubing to displace fluid from the drip chamber through the output tubing; an inlet valve disposed between the drip chamber and the pumping section and arranged to compress the output tubing to restrict or block flow through the output tubing; and a second actuator, controllable using the microprocessor, for opening or closing the inlet valve independent of the displacement of the plurality of fingers; or for operating the inlet valve to control a rate of flow of fluid from the drip chamber to the portion of the output tubing, such that the pump can be used in a pumping mode or a gravity infusion mode.
A system for monitoring hemodynamics of a subject is disclosed. The system comprises: a signal generating system configured for providing at least an output electric signal and transmitting the output signal to an organ of the subject. The system also comprises a demodulation system configured for receiving an input electrical signal sensed from the organ responsively to the output electric signal, and for modulating the input signal using the output signal to provide an in-phase component and a quadrature component of the input signal. The system also comprises a processing system configured for monitoring the hemodynamics based on the in-phase and the quadrature components.
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