The mass spectrometer according to the present disclosure is a mass spectrometer that generates a group of product ions from a precursor ion derived from a sample component having a hydrocarbon chain and performs mass spectrometry thereon, and includes a reaction chamber, an electrode, an introduction unit, a mass separation unit, a detection unit, a power supply unit, and a controller. The controller performs mass spectrometry on the sample component while alternating between a first analysis mode in which ions are detected in a first polarity mode and in a multimode, and a second analysis mode in which ions are detected in a second polarity mode and in a single mode.
To reduce deformation of a stator in an upper-lower direction. A vacuum pump includes a rotor housed in a housing and rotationally driven, plural stages of rotor blades provided in the rotor, and plural stages of stators, each of which is disposed between adjacent ones of the plural stages of rotor blades. The stator has an inner peripheral rib, an outer peripheral rib, and a stator blade connecting the inner peripheral rib and the outer peripheral rib, and is housed in the housing in a state of the outer peripheral rib being sandwiched between spacers. At least part of the outer peripheral rib of the stator is provided with a deformable portion configured to allow deformation of the inner peripheral rib and/or the stator blade in a radial direction.
A mass spectrometry method including: a preparation step (step 1) of adding a predetermined alkali metal ion to a liquid sample; an ionization step (step 3) of ionizing a target compound contained in the liquid sample to which the alkali metal ion has been added; and a measurement step (step 7) of measuring an intensity of an adduction formed in the ionization step by an addition of the predetermined alkali metal ion to the target compound, or an intensity of a product ion derived from the adduct ion.
A phase contrast X-ray imaging apparatus (100) according to this disclosure includes an X-ray source (1); an X-ray detector (2); a plurality of gratings; an image processor (7a) for generating a first dark field image (35a); a storage (8) for storing a plurality of correction curves (20a) generated at positions in a direction perpendicular to a grating direction; and a controller (7b) for correcting the first dark field image by using the correction curves corresponding to the positions, wherein each of the plurality of correction curves represents an assignment relation between values that relate to X-ray absorption of a subject (90) and values that relate to X-ray scattering of the subject at corresponding one of the positions.
G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays
5.
Accelerated Deterioration Test Apparatus, Accelerated-Deterioration-Test Analysis System, and Accelerated Deterioration Test Method
An accelerated deterioration test apparatus (101) according to this invention includes a container (10) configured to be able to accommodate a sample (200) as a subject of an accelerated deterioration test for accelerating deterioration of the sample (200) as the test subject by using a deterioration factor for deteriorating the sample; and an introducer/collector (120) connected to the container (10) to introduce a gas or a liquid as the deterioration factor into the container (10) and to collect, during the accelerated deterioration test, a product that appears with the deterioration of the sample (200).
Provided is an angle adjustment member for an optical element, the angle adjustment member including: two actuators; and a center bar of which a tip portion is movable in 360°. Furthermore, in order to provide a micro-Raman spectroscopic device capable of performing adjustment of an optical axis without opening a device housing and capable of further performing fine adjustment of the optical axis with out imposing an excessive burden on an adjuster, at least one of an incident light optical element and a Raman light optical element has the angle adjustment member.
A flow-path switching device includes a column pipe connected to the separation column, a first rotating body which has a first port and a first sliding surface, and in which a first through hole penetrating the first port and the first sliding surface is formed, and a second rotating body having a second sliding surface facing the first sliding surface, wherein the second rotating body is rotatable with the first sliding surface being in contact with the second sliding surface, and a second through hole is formed in the second rotating body, one end of the second through hole is connectable to the first through hole when a rotation position of the second rotating body with respect to the first rotating body is a first position, and another end of the second through hole is connected to the column pipe.
Provided is a mass spectrometry method for post-translational modification and/or fragmentation of tau protein in a biological fluid, the method enabling stable detection of both modified endogenous tau fragments that include post-translational modification sites such as phosphorylation, and unmodified endogenous tau fragments, without requiring the performance of additional fragmentation processing on a group of endogenous tau fragments in the biological fluid. The method includes: a step of extracting endogenous tau fragments derived from tau protein in a biological fluid sample to obtain a group of endogenous tau fragments; a step of performing mass spectrometry on the group of endogenous tau fragments to obtain mass-to-charge ratio (m/z) and intensity information for each of the endogenous tau fragments, and thereby conducting mass profiling of the group of endogenous tau fragments; and a step of analyzing at least one of the difference in fragmentation of tau protein and the difference in post-translational modifications of tau protein between samples by comparing the mass profiling results of the groups of endogenous tau fragments between samples.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
9.
METHOD AND APPARATUS FOR CONSTRUCTING DATABASE FOR MICROBIAL IDENTIFICATION
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Ogata, Koretsugu
Sekiguchi, Yuji
Miura, Daisuke
Abstract
A method of constructing a microbial identification database, the method comprising: (ST02) acquiring genome data for microorganisms from a genome database; (ST06) determining whether a criterion is satisfied by the genome data thus acquired; (ST16) for respective sets of the genome data that were determined that they satisfied the criterion, predicting proteins to be expressed; and (ST20A, 20C) constructing a mass-to-charge ratio database including mass-to-charge ratio lists, the mass-to-charge ratio lists being predicted for the respective sets of the genome data based on the proteins thus predicted.
A data processing method is performed by a computer to correct measurement values of a prescribed component obtained by measurement with an analysis device. The data processing method includes: receiving the measurement values; and calculating a first reference value and a second reference value using the measurement values. The data processing method includes correcting the measurement values using the first reference value and the second reference value.
A mass spectrometer according to an embodiment of the present invention comprises a voltage generation unit (53) that generates an RF voltage to be applied to an electrode forming a quadrupole mass filter. The voltage generation unit includes: an RF signal generation unit (530) that generates a sine wave signal using a DDS; a first filter (531) that removes high-frequency noise superposed on the sine wave signal; a waveform conversion unit (5320) that receives a sine wave signal that is an output of the first filter as an input, and generates a rectangular wave signal having a frequency of 1/N (where N is an integer of at least one) of the frequency of the sine wave signal; and a second filter (5321) that converts the rectangular wave signal generated by the waveform conversion unit into a sine wave signal, by removing high-frequency components from the rectangular wave signal.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Sekiguchi, Yuji
Miura, Daisuke
Abstract
A microbial identification method comprising: (ST32) acquiring a sample list that is a list of mass-to-charge ratios for a sample; (ST40 to ST44, ST40A) identifying the sample by comparing the sample list with a mass-to-charge ratio database with weights assigned to mass-to-charge ratios for proteins included in a specific group, the mass-to-charge ratio database being a database of mass-to-charge ratio lists respectively for microorganisms predicted from genome data; and (ST50, ST54) outputting results of the identifying.
The fluorescent X-ray analysis method includes: placing a sample in a fluorescent X-ray analysis apparatus (S1); calculating a reference tube current of an X-ray tube by applying a desired dead time rate to a paralyzed model (S3); determining a measurement tube current of the X-ray tube based on the reference tube current and irradiating the sample with X-rays generated by applying the measurement tube current to the X-ray tube (S4); and analyzing fluorescent X-rays obtained by irradiating the sample with the X-rays (S5). Thus, a desired dead time of the counting circuit can be obtained with high accuracy.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
15.
X-RAY IMAGING SYSTEM AND X-RAY IMAGE DISPLAY METHOD
An X-ray imaging system according to this invention includes an X-ray irradiator for irradiating a subject who is in loaded action in which a load is applied to legs of the subject with X-rays; an X-ray detector; a load information acquirer for acquiring load information to identify a state of the load applied to the leg or the legs in the loaded action of the subject separately from the detection of the X-rays; a display; and a controller. The controller executes control for identifiably displaying at least an X-ray image that corresponds to a maximum load timing in which a largest load is applied to one of legs of the subject in loaded action on the display based on the load information.
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
This liquid chromatograph comprises: a sample injection flow path; an analysis pump that guides a mobile phase to the sample injection flow path; a sample injection unit that guides a sample to the sample injection flow path; a flow path switching unit; a separation column that separates the sample that has passed through the sample injection flow path; and a detector that detects the sample that has passed through the separation column. The sample injection flow path includes: a first merging unit that is connected to the sample injection unit and the analysis pump; a weighing flow path; and a first branching unit.
A method of processing structured data related to an experiment includes creating structured data by using a computer, and generating a control signal for operating an automatic experimental apparatus based on the structured data. The structured data includes a plurality of sets of items and values for conducting a predetermined experiment with the automatic experimental apparatus. The creating the structured data includes extracting, from a first information source, a first value to be input to the set, and adding a second value to a blank field of the set.
G06F 16/483 - Retrieval characterised by using metadata, e.g. metadata not derived from the content or metadata generated manually using metadata automatically derived from the content
In an ion source 100 configured to generate ions by a process involving an electric discharge, at least the surface of at least an anode 121 of discharging electrodes included in the ion source is made of titanium in order to prevent a decrease in the power output of the ion source due to the formation of an oxide film on an electrode surface. Titanium has the nature that it forms a film on its surface through oxidization and yet does not lose its electric conductivity even when oxidized. Therefore, the power output of this ion source will not decrease even when an oxide film is formed on the surface of the anode, so that it can be used for a long period of time without requiring the electrode polishing or similar tasks.
A nebulizer includes: a nozzle portion provided with an ejection port through which gas is ejected; and a capillary having a tip end portion disposed to protrude from the ejection port. A plurality of protruding portions protruding inward in a radial direction of the ejection port are arranged side by side in a circumferential direction on a portion of an inner circumferential surface of the nozzle portion, the portion of the inner circumferential surface defining the ejection port. The plurality of protruding portions are provided to define an inscribed circle. The capillary passes through inside the inscribed circle.
An X-ray imaging apparatus according to this invention includes an X-ray-image-and-voice-information collector for collecting a plurality of X-ray images based on detection results of X-rays with which a patient is irradiated, and for collecting voice information on the patient's voice input from a voice information input part; an X-ray image preserver for preserving the plurality of X-ray images collected together with time information; a voice information preserver for preserving the voice information collected together with time information; a timing identifier for identifying a timing in which the speech of the patient is different from the examination sentence based on the voice information preserved; an X-ray image identifier for identifying a corresponding X-ray image that corresponds to the timing in the plurality of X-ray images preserved; and a display controller for directing a display to display the corresponding X-ray image.
Provided is a gas chromatograph capable of efficiency circulating air in a column oven. The gas chromatograph is provided with a column oven, a heater, a fan, and a cylindrical member. The column oven accommodates a column. The heater heats the inside of the column oven. The fan has a blade that rotates about a rotation axis in the column oven, and sends air toward the column provided in the axial direction that is a direction along the rotation axis. The cylindrical member is arranged to accommodate at least a part of the fan in a state of being spaced apart from the column in the axial direction and surrounding an outer periphery of the fan along a rotational direction of the blade.
A vacuum pump includes a housing having a suction port, a rotor housed in the housing and rotationally driven to suck gas through the suction port and pump the gas, and a lid member that covers a recess of the rotor. The lid member has a cone shape having a vertex on a side close to the suction port and having a bottom on a side close to the rotor. The generatrix of the cone shape includes a first curved portion having such a curve that an angle between a tangent to the generatrix and a gas flow direction increases from a vicinity of the vertex to a vicinity of the bottom.
A computer (132) obtains image data (step S10), extracts from the image data as an edge pixel a pixel satisfying a condition that a result of comparing with an adjacent pixel is an edge (step S12), and generates first data by dilating an edge including the edge pixel (step S14). Then, the computer (132) uses the first data to generate second data that determines a region in a sample corresponding to a substrate (step S22).
A method for nucleic acid structure analysis using an ion trap type mass spectrometer having an ion source performing MALDI includes: an ionization step of ionizing a nucleic acid contained in a sample by the ion source; an ion dissociation step of dissociating a protonated molecule or a deprotonated molecule of the nucleic acid generated in the ionization step by collision-induced dissociation inside an ion trap of the mass spectrometer to generate a plurality of fragment ions; a mass spectrometry step of performing mass spectrometry on the plurality of fragment ions generated in the ion dissociation step to acquire mass information of the plurality of fragment ions; and a structure determination step of determining at least a part of a structure of the nucleic acid based on the mass information of the plurality of fragment ions acquired in the mass spectrometry step.
A sample information setting method for setting information on a sample in an injection device for injecting a sample into each of a plurality of injection targets, includes a step of displaying a plurality of first images corresponding to the plurality of injection targets, respectively; a step of displaying a second image showing, as a menu, information on at least one sample capable of being set to the injection target corresponding to the first image included in a region within an array of the plurality of injection targets, in response to completion of a first operation of selecting the region by a dragging operation, the region including the first image of the injection target; and a step of setting the information on the sample selected by a second operation to the injection target corresponding to the first image included in the region.
This method for identifying acid shock proteins comprises: (i) a step for preparing a first solution containing an acid shock protein produced by a predetermined type of microorganism at a first concentration and a second solution containing the acid shock protein produced by the predetermined type of microorganism at a second concentration lower than the first concentration; (ii) a step for measuring a first mass spectrum and a second mass spectrum corresponding respectively to the first solution and the second solution; and (iii) a step for comparing the first mass spectrum and the second mass spectrum to determine a specific peak corresponding to the acid shock protein in each mass spectrum in accordance with the degree to which the peak intensity is maintained in the second mass spectrum.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
28.
X-Ray Imaging Apparatus and Method for Adjusting Current to Be Supplied to Filament
An X-ray imaging apparatus includes an X-ray tube including an electron emitter including a filament, a storage to store current information acquired in advance, in which a total supply time of a current to be supplied to the filament is associated with an appropriate current value to be supplied to the filament, and a controller configured or programmed to perform a control to adjust the current to be supplied to the filament based on the current information after a first total supply time as a predetermined total supply time.
H05G 1/46 - Combined control of different quantities, e.g. exposure time as well as voltage or current
G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
Provided is a non-contact sleep state measurement system 100 capable of accurately measuring a sleep state regardless of age, disease, or the like of a subject. The sleep state measurement system includes: a frame image acquisition unit that acquires frame images including a subject P during sleep in time series; a difference information calculation unit that calculates difference information that is information indicating a difference between two frame images at different times; a subject attribute information acquisition unit that acquires subject attribute information that is information indicating an attribute of the subject; and a sleep state related information calculation unit that calculates sleep state related information that is information related to a sleep state of the subject using the difference information or secondary information obtained therefrom as an explanatory variable according to the subject attribute information.
A holder holds a battery which is subjected to X-ray analysis. The battery includes a positive electrode and a negative electrode. A sample chamber for disposing the battery therein is formed inside the holder. The holder includes a body, a beryllium plate, a first resin member, a conductive member, a positive electrode terminal, and a negative electrode terminal. An upper surface of the body is formed with a window. The beryllium plate is arranged in the window. The first resin member is provided on a surface of the beryllium plate. The conductive member is provided between the positive electrode and the first resin member so as to be in contact with the positive electrode of the battery. The positive electrode terminal is electrically connected to the conductive member. The negative electrode terminal is electrically connected to the negative electrode.
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
G01N 23/207 - Diffractometry, e.g. using a probe in a central position and one or more displaceable detectors in circumferential positions
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
An analytical method for performing, in parallel, a first analysis step of introducing a non-derivatized first sample 132 into a first column 44 together with a first mobile phase 54, and analyzing components contained in the first sample 132; and a second analysis step of introducing a derivatized second sample 137 into the second column 84 together with a second mobile phase 94, and analyzing components contained in the second sample 137, wherein the first sample 132 contains inosinic acid and guanylic acid, and in the first analysis step, by separating components contained in the first sample 132 using the first column 44 having a length of 185 mm or more, a chromatogram is obtained in which peaks corresponding to inosinic acid and guanylic acid are separated with a separation degree of 1.5 or more.
Provided is a biomagnetism measurement apparatus in which sufficient consideration is given to the fact that optimal arrangement of a sensor with respect to a subject varies depending on the purpose of the measurement. The biomagnetism measurement apparatus of the present invention has the following configuration. That is, the biomagnetism measurement apparatus of the present invention includes: a magnetic sensor group that is disposed outside a body of a subject and measures biomagnetism of the subject; and an arithmetic device that acquires an arrangement pattern of the magnetic sensor group corresponding to a content of the measurement based on information indicating the content of the measurement.
The X-ray imaging system generates a three-dimensional model of a device based on a first X-ray image and a second X-ray image. The X-ray imaging system determines an inaccurate portion of the shape in the three-dimensional model (81) by identifying a parallel portion extending along a direction parallel to the epipolar line, from the device having a linear structure. The X-ray imaging system displays the three-dimensional model and a display based on the determination result of the inaccurate portion of the shape in the three-dimensional model.
A mass spectrometer (100) comprises an ionization chamber (200), ion guides (23, 25), a detector (28), and a control device (3). The control device is configured to execute a determination process. The determination process includes: a process of measuring a first ion intensity; a process of measuring a second ion intensity when a first period has elapsed after the measurement of the first ion intensity; a process in which the polarity mode is switched from a first polarity mode to a second polarity mode after the measurement of the second ion intensity, the polarity mode is returned to the first polarity mode when a second period shorter than the first period has elapsed, and a third ion intensity is measured; and a process of outputting a display signal for displaying, to a user, a determination result that the degree of contamination of the ion guides satisfies a contamination criterion.
A classification method according to the present invention comprises: a first step for focusing on target particles in a separation channel; a second step for subjecting the target particles to a cross flow flowing in a first direction, and then distributing the target particles in the first direction in the separation channel; a third step for distributing the target particles after the second step in the longitudinal direction in the separation channel such that a first particle group and a second particle group included in the target particles can flow out, in that order, from an outlet port of the separation channel; a fourth step for subjecting the second particle group after the third step to a reversed cross flow flowing in a second direction, which is the direction opposite to the first direction, thereby moving the second particle group in the second direction from the side of a membrane in the separation channel; a fifth step for causing the first particle group and the second particle group to flow out, in that order, from the outlet port to outside of the separation channel; and a sixth step for detecting, using a detector, the second particle group that has been made to flow out through the outlet port.
B03B 5/62 - Washing granular, powdered or lumpy materialsWet separating by hydraulic classifiers, e.g. of launder, tank, spiral or helical chute concentrator type
G01N 15/02 - Investigating particle size or size distribution
A mass spectrometer (1) capable of performing mass spectrometry by generating ions from a sample through a first ionization method and a second ionization method comprises: an ion transport optical system (211, 212, 221, 222, 231, 232) into which generated ions are introduced and which includes a plurality of electrodes arranged along a flight path of the ions; a mass spectrometry unit provided with mass separation parts (242, 252, 254, 255, 256) for separating the ions according to the mass-to-charge ratio ; a storage unit (51) in which information on a first applied voltage to be applied to the plurality of electrodes is stored; a second applied voltage generation unit (53) that, when the first applied voltage includes a value of a voltage that forms a rising gradient of a potential inside the ion transport optical system, changes the value of the voltage to generate a second applied voltage in which the rising gradient is suppressed; and an analysis execution unit (54) that applies the second applied voltage to the plurality of electrodes and performs mass spectrometry of ions generated through the second ionization method.
A gas flow path switching device (1) comprises: a plate-like flow path plate (250); a first microvalve (201); and a second microvalve (202). A first flow path (271), a second flow path (272), and a third flow path (273) are formed in the flow path plate (250). The first microvalve (201) is configured to be able to switch connection and disconnection between the first flow path (271) and the second flow path (272). The second microvalve (202) is configured to be able to switch connection and disconnection between the first flow path (271) and the third flow path (273). The first microvalve (201) and the second microvalve (202) are arranged on both surfaces (250a, 250b) of the flow path plate (250).
G01N 30/26 - Conditioning of the fluid carrierFlow patterns
G01N 30/46 - Flow patterns using more than one column
41.
METHOD FOR FORMULATING ANALYSIS SAMPLE OF COMPONENT DERIVED FROM BIOPOLYMER-PRODUCING MICROORGANISM, ANALYSIS METHOD, AND METHOD FOR IDENTIFYING BIOPOLYMER-PRODUCING MICROORGANISM
A method for formulating an analysis sample of a component derived from a biopolymer-producing microorganism according to the present invention comprises: a step for preparing a sample solution containing constituent components of the microorganism and the biopolymer; a step for centrifuging the sample solution; a step for performing ultrafiltration of a supernatant obtained through the centrifugation; and a step for formulating an analysis sample using a filtrate or a residue obtained through the ultrafiltration.
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
A first diffraction grating (11) is installed at a first position (P1) and diffracts and spectrally resolves X-rays from an X-ray source (3). A second diffraction grating (12) is installed at a second position (P2) and diffracts and spectrally resolves X-rays from the X-ray source (3). Blocking parts (41, 42) are configured so as to be able to block both a first optical path (71) of the X-rays from the X-ray source (3) diffracted by the first diffraction grating (11) and incident on a detector and a second optical path (72) of the X-rays from the X-ray source (3) diffracted by the second diffraction grating (12) and incident on the detector (2). A control device (91) controls the blocking parts (41, 42) so as to selectively block one of the first optical path (71) and the second optical path (72).
G21K 1/06 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diffraction, refraction, or reflection, e.g. monochromators
A laser beam irradiation apparatus (1) includes a plurality of laser light sources (10), an optical fiber (30), and a coupling optical system (20). The coupling optical system (20) includes a reduction optical system (22). The reduction optical system (22) includes a lens (23a) and a lens (24a). The lens (23a) is made of a first glass material. The lens (24a) is made of a second glass material. A second energy gap of the second glass material is greater than a first energy gap of the first glass material.
A cell image analysis system (100) according to this invention includes a data tree creator (11), a graph creator (12), and a display controller (13). The display controller is configured to display a second data tree (24b) that is different from a first data tree (24a), and has horizontal and vertical axis parameters that are common to the first data tree, and, when the second data tree is selected by a user, to update a graph by adding the analysis results of cell images (30) that are included in the second data tree selected by the user to the graph.
This teaching device is for setting a reference position of a rotor (16) of a multi-port valve (2) configured so as to switch, according to rotation of the rotor (16), a communication state between a plurality of connection ports (14) for fluidly connecting piping. The teaching device comprises: the multi-port valve (2); a control unit (12) that controls the operation of the multi-port valve (2); and sensors (8; 30) provided so that an output signal changes according to the position of the rotor (16) of the multi-port valve (2). The control unit (12) is configured to rotate the rotor (16) by small angles while reading the output signal of the sensors (8; 30) in teaching for setting the reference position of the rotor (16), and to set the reference position on the basis of the value of the output signal of the sensors (8; 30).
F16K 31/04 - Operating meansReleasing devices electricOperating meansReleasing devices magnetic using a motor
F16K 11/074 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members with flat sealing faces
Laser beams condensed by a condensing optical system are incident on an optical fiber (200). An irradiation mechanism (301) irradiates an object with light that comes out of the optical fiber (200). A movement mechanism (302) moves an irradiation region in the object irradiated with laser beams. The optical fiber (200) includes a core including an incidence plane on which laser beams condensed by the condensing optical system are incident. The incidence plane is in such a first elongated shape that a first direction is longer than a second direction, the first direction and the second direction being orthogonal to each other. The irradiation region is in a second elongated shape corresponding to the first elongated shape. The movement mechanism (302) moves the irradiation region in the first direction.
An image generator built by machine learning is stored in an image-generator storage section (31). The image generator receives an image having a missing region and fills that region with a complementary image. An inspection target image is stored in an image storage section (32). A missing-image generator (44) generates, from the inspection target image, a missing image (63) in which a region is missing, a window (62) having a specified shape and size being applied on the region. A complemented-image generator (45) generates a complemented image (65) having the region filled with a complementary image by inputting the missing image into the image generator. A difference acquirer (46) determines a difference (66) between the inspection target image and the complemented image. A determiner (47) determines whether the region is normal or abnormal by comparing the difference with a predetermined criterion.
G01N 23/18 - Investigating the presence of defects or foreign matter
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
48.
Management System, Server, Method, and Non-Transitory Computer Readable Medium
A management system that provides a virtual space to a user includes a user apparatus used by the user, a sensor configured to observe change over time of a target present in a real space, and a server configured to transmit information for providing the virtual space to the user apparatus. The server is configured to obtain a detection result by the sensor, calculate a degree of change of the target based on the detection result, and arrange in the virtual space, an object representing the target on which the degree of change is reflected.
A device for processing mass spectrometry data (40) includes: a storage section (41) which holds information in which reagent-identifying information is related to the mass-to-charge ratio of an ion to be generated from the reagent; a display section (60); a mass-spectrum-data input receiver (42); a reagent-information input receiver (45) configured to receive an input of the reagent identification information of a reagent added to a sample; a peak locator (46) configured to compare the inputted reagent identification information with the information stored in the storage section, and to locate a peak associated with an ion generated from the reagent; and a display processor (47) configured to create a mass spectrum from the mass spectrum data, and to display, on the display section, the mass spectrum in such a manner that the peak located by the peak locator is shown in a form distinguishable from other peaks.
The present disclosure relates to the field of ion mobility analysis, and specifically provides a tandem U-shaped ion mobility spectrometer and an ion mobility analysis method. The tandem U-shaped ion mobility spectrometer includes two U-shaped ion mobility analyzers coupled in series. A first U-shaped ion mobility analyzer operates in a filter mode, and a second ion inlet of a second U-shaped ion mobility analyzer is disposed corresponding to a first ion outlet. An ion dissociation device is configured to receive and dissociate ions from the first U-shaped ion mobility analyzer and release fragment ions generated by the dissociation to the second U-shaped ion mobility analyzer. The tandem U-shaped ion mobility spectrometer reduces a complexity and a precision requirement of applying an electric field, has a high resolution and a dynamic range, and is suitable for studies of complex topics such as biomics.
There is provided a highly flexible sterilization method that is also safe and optimal. This sterilization method includes sterilization area setting in order to set in advance a sterilization area within a predetermined area of human activity, peripheral area setting in order to set in advance peripheral areas that are adjacent to or in proximity to the sterilization area, irradiation mode deciding in order to decide an irradiation mode for irradiating sterilization electromagnetic waves onto the sterilization area based on peripheral area information acquired from the peripheral areas, and sterilization electromagnetic wave irradiating in order to irradiate sterilization electromagnetic waves onto the sterilization area in the irradiation mode.
An X-ray imaging device (100) comprises: an imaging part (2) that includes an arm (22) that connects an X-ray source (20) and a detector (21); a drive part (3) that moves the arm (22); a touch operation button (81) that receives an operation for changing the imaging angle of the imaging part (2); and a control part (9) that, each time the touch operation button (81) is operated, performs control to move the arm (22) in a prescribed direction by the drive part (3) and change the imaging angle by a unit angle amount (change width θ).
In a mass spectrometer, a linear ion trap unit (2) has an ion-capturing space formed by rod electrodes (20) surrounding a central axis (C) and an auxiliary electrode (21) provided outside an ion-ejection end of the rod electrodes or protruding from the ion-ejection end. An extracting electrode (23) is located further outside the auxiliary electrode. An RF voltage generator (50) applies RF voltages to the rod electrodes and the auxiliary electrode to create an RF electric field within the ion-capturing space. An extracting voltage generator (52) applies a DC voltage to the extracting electrode so that a DC electric field for ion extraction reaches the ion-capturing space. A controller (4) controls the RF and extracting voltage generators to eject ions from the ion-capturing space along the central axis according to their m/z by changing the RF voltage or the DC voltage when the ions are confined within the ion-capturing space.
The disclosure relates to the field of ion mobility analysis, and particularly provides a tandem ion mobility spectrometer and an ion mobility analysis method. The tandem ion mobility spectrometer incorporates an ion dissociation device into a basic structure of a UMA, enabling ion mobility spectrometric analysis of ions within a target mobility range as well as fragment ions resulting from dissociation of the ions, achieving higher resolution. Additionally, by configuring an electric field in a first channel to allow ions to accumulate therein, when the ions within the target ion mobility range are released, ions outside the target ion mobility range which need to be analyzed can remain stored in the first channel and be released for analysis later, making ion utilization more efficient.
Provided is a method for measuring a measurement sample containing a hypochlorite ion by liquid chromatography mass spectrometry, the method including selecting a mass chromatogram indicating the presence of a hypochlorite ion-derived iron complex from a plurality of mass chromatograms obtained by liquid chromatography mass spectrometry to determine an abundance of the hypochlorite ion.
A monitoring analysis device includes a reaction product acquirer that sequentially acquires reaction products produced by a reaction device, an analyzer that sequentially analyzes the reaction products acquired by the reaction product acquirer, an analysis controller that causes the analyzer to execute a batch analysis in which a plurality of set analyses are sequentially executed according to a set analysis condition, and an analysis condition changer that, during execution of the batch analysis by the analyzer, and during or after execution of any analysis among the plurality of set analyses, is configured to change the set analysis condition for an analysis that is to be executed after the any analysis and is subject to a change.
This X-ray imaging device (100, 110) comprises: a storage unit (3) that stores registered imaging information (30) containing a plurality of registered target positions (P); and a control unit (5) that performs control to move at least one of an X-ray imaging unit (2) and a top plate (11) to a set target position that has been set. The control unit (5) is configured to set a first-selected first target position (P1) as the set target position without receiving an input operation for starting a first mode after at least one of the X-ray imaging unit 2 and the top plate 11 has been moved to a last-selected second target position (P3).
This X-ray imaging system (100) comprises: an X-ray imaging device (1) provided with an X-ray irradiation unit (10) and an X-ray detection unit (11); a detection unit (12) for detecting a subject (101); an input reception unit (3); and a control device (2) that performs control for starting, on the basis of the subject being detected, measurement of a positioning time (40), which is the time until alignment of the subject and the X-ray irradiation unit is completed, ending measurement of the positioning time and acquiring the positioning time on the basis of receipt of an operation input performed by an operator after positioning of the subject and the X-ray irradiation unit is completed, and outputting the acquired positioning time.
Provided is an ion analyzer for analyzing an ion using radical-induced dissociation. A generator (21, 210) generates a radical from a source gas. A gas supplier (26, 3) supplies a gas mixture as the source gas to the generator during an analysis. The gas mixture is prepared by mixing a first gas which is a source for a radical having oxidizing power or which itself has oxidizing power, and a second gas which is a source for a radical having reducing power or which itself has reducing power, at a predetermined ratio specified so that the efficiency of dissociation by the radical originating from the first gas is not lower than that when the second gas is not mixed. A radical generated by the generator is introduced into a reaction chamber (132), within which an ion originating from a sample is dissociated by coming in contact with the radical.
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
SHIMADZU CORPORATION (Japan)
Inventor
Andrzejewski, Roch
Abstract
A fluorescence lifetime imaging device for imaging the fluorescent output of a target fluorophore at an imaged subject spaced from the imaging device by a spacing. The imaging device comprises a light source configured to emit excitation light for fluorescent excitation of the target fluorophore. A first optical sensor is configured to detect returned excitation light scattered from the imaged subject, and a second optical sensor is configured to detect fluorescent light emitted by the fluorophore in response to excitation thereof by the excitation light, and to output a corresponding fluorescence intensity detection output. An image data generating unit is configured to generate data describing fluorescence lifetime images based on said fluorescence intensity detection output according to a time of occurrence of said detection of returned excitation light corresponding to a time-of-flight of excitation light across said spacing between the light source and the imaged subject.
This liquid collection and injection device for collecting a liquid and injecting the liquid into a predetermined place includes: a tubular tip (153) for suctioning and discharging the liquid in a state in which the leading end of the tip is directed downward; movement mechanisms (160, 181, 182) for moving the tip in a three-dimensional space; an imaging unit (155) for imaging the leading end of the tip; a photoelectric sensor (170) having a light projection unit (171) and a light reception unit (172); and a position specifying unit (123) for specifying a position in the three-dimensional space of the leading end of the tip on the basis of an image of the leading end of the tip imaged by the imaging unit and detection information obtained by detecting the leading end of the tip by means of the photoelectric sensor.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
An atomic absorption spectrophotometer (1), including: a sample collection unit (24) to which a chip (25) configured to collect and eject a sample is attached; a sample heating unit (11) configured to excite the sample, provided with an opening (14) in an upper face into which the sample is injected from the sample collection unit (24); a moving mechanism (27) configured to move the sample collection unit between a first position for collecting the sample into the chip and a second position for injecting the sample from the chip to the opening; a light irradiating unit (29) configured to irradiate a light on the opening from a predetermined lighting direction; and an image acquisition unit (26) configured to image the opening from an optical axis direction different from the lighting direction.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/74 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light thermally excited using flameless atomising, e.g. graphite furnaces
A preparative chromatograph system (1) includes a fractionation collecting condition correction part (18) configured to detect a change in a chromatogram acquired in each of a plurality of injections of a sample during stack injection fractionation collecting and to correct a fractionation collecting condition during the stack injection fractionation collecting so that the chromatogram approaches a state before the change, wherein the stack injection fractionation collecting continues based on the corrected fractionation collecting condition after the fractionation collecting condition correction part (18) has corrected the fractionation collecting condition.
B01D 15/24 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
B01D 15/14 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
A preparative chromatograph system includes: a chromatograph part including a separation column and a detector; a fraction collector for executing a fractionation collecting operation of dropping and collecting the eluate flowed out from the separation column through a nozzle into a plurality of collection containers; a controller configured to control an operation of the fraction collector based on a preset fractionation collecting condition; an information processing device configured to perform information processing relating to the fractionation collecting operation; and a display. The information processing device is configured to output a chromatogram created based on a signal of the detector to the display in a state where fractionated sections on the chromatogram collected in the plurality of collection containers by the fraction collector and collection information including a collection purpose for which each fractionation section has been collected are added to the chromatogram.
A treatment support apparatus (100) includes an excitation light source (21) configured to irradiate a fluorescent substance (301) of a drug (300) administered into a cancer patient's (200) body with excitation light in a specific waveband having energy that excites the fluorescent substance (301) but does not kill a cancer cell (301) before or after treatment to kill the cancer cell (201) based on irradiating the drug (300) containing the fluorescent substance (301) with light in a specific waveband, a fluorescence detector (26) configured to detect fluorescence emitted by the fluorescent substance (301) of the drug (300) due to excitation by the excitation light, and an image generator (16) configured to generate a fluorescence distribution image (41), which is an image showing a distribution state of the fluorescence emitted by the fluorescent substance (301), based on the fluorescence from the fluorescent substance (301) detected by the fluorescence detector (26).
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
Andrzejewski, Roch
Knight, Patrick
Shvartsburg, Alexandre A.
Abstract
VDD EDD D , across the analytical gap containing the flow of gas. The drift region is irradiated with light from a light source thereby to irradiate the ions entrained within the flow of gas contained therein such that the entrained ions are subject to the dispersion electric field and the light from the light source.
A stress light emission measurement device (100) comprises an excitation light source (50), an imaging device (60), optical filters (F1, F2), and a processing device (70). The excitation light source (50) is configured to irradiate a stress light-emitting body (90) with excitation light before and during application of external force to the stress light-emitting body. The imaging device (60) images light emitted by the stress light-emitting body (90). The optical filters (F1, F2) remove an excitation light component from the captured image. The processing device (70) calculates, on the basis of the captured image produced by the imaging device (60), a stress light emission image that indicates stress light emission when external force is applied to the stress light-emitting body (90).
G01N 21/70 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light mechanically excited, e.g. triboluminescence
This scanning probe microscope (100) for subjecting the surface of a sample (S) to analytical processing comprises: a cantilever (101); a detecting device (12) for detecting a physical characteristic of the cantilever (101); and a control device (11) for identifying the spring constant of the cantilever (101) on the basis of the physical characteristic detected by the detecting device (12). The control device (11) stores specific information (Tb1) for identifying the spring constant on the basis of the physical characteristic, acquires the physical characteristic detected by the detecting device (12), and identifies the spring constant on the basis of the acquired physical characteristic and the specific information (Tb1).
The present disclosure relates to: a proportional counter (10) comprising a container (11) and a core wire (12) disposed within the container (11), wherein a gas is sealed within the container (11), the container (11) is provided with an entrance window (13), and a graphene sheet (14) is disposed in the entrance window (13); and a wavelength dispersive fluorescent x-ray analysis device (20, 40). The present disclosure provides the gas-filled proportional counter (10) that can be used for fluorescent X-ray analysis of ultra-light elements, and the wavelength dispersive fluorescent x-ray analysis device (20, 40) including the gas-filled proportional counter.
G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
Provided is a method for analyzing a neurogranin-related peptide by matrix assisted laser desorption/ionization-mass spectrometry, in which a laser irradiation target contains the neurogranin-related peptide, a matrix, and a protein of 9 kDa or more, and a content of the protein per 1 μg of the matrix is 10 fmol or more and 600 fmol or less.
Provided is a technique for providing objective and highly accurate information for taste evaluation. A device acquires information about respective amounts of two or more types of components in a target (step S21). The two or more types of components are associated with a specific taste. The device derives a determination result as to whether the target has the specific taste, based on ratio information about a ratio of each of the two or more types of components and information about an amount of each of the two or more types of components (step S23), and outputs the determination result (step S24).
A time-of-flight mass spectrometer (100) is provided with: an ejection unit (27) that ejects ions for each sequence; a flight tube (32); an ion detector (35); and a signal processing device (7) that generates a mass spectrum on the basis of detection values from the ion detector and outputs a display signal for displaying the mass spectrum. The signal processing device generates one-shot data for each sequence using the detection values and, after correcting the one-shot data, generates the mass spectrum through a process (S10) of integrating the corrected one-shot data. The correction includes shift correction that shifts the one-shot data in the flight time axis direction.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
74.
Method of Quantifying Antigen-Binding Molecule Bound to Cells
Provided is a method of quantifying an antigen-binding molecule bound to cells, comprising: a preparation step of preparing a biological sample derived from the cells, wherein the biological sample is homogenized, the cells express a target antigen bound specifically to the antigen-binding molecule, and the cells have been exposed to the antigen-binding molecule; an extraction step of adding an extraction solution to the biological sample to obtain an analyte, wherein the extraction solution comprises an organic acid and a nonionic surfactant, and the extraction solution has a pH of 1 or more and 3 or less; and a quantification step of analyzing the analyte to quantify the antigen-binding molecule.
This experimental system comprises: an experimental device capable of simultaneously executing a plurality of experiments with dissimilar experimental conditions; and a search device for searching for experimental conditions to be used in the experimental device. The search device sets a first experimental condition using a first experiment planning method, controls the experimental device so that the experimental device executes a first experiment based on the first experimental condition, and sets a second experimental condition using a second experiment planning method on the basis of the result of the first experiment. Each of the first experiment planning method and the second experiment planning method includes a Bayesian optimization method using a first acquisition function, and a Bayesian optimization method using a second acquisition function different from the first acquisition function.
A cell cultivation apparatus (100) according to this invention includes a device holder (101), and gas pipes (31) for supplying a gas to cultivation chambers (23). The device holder includes a holder-side lid (10) including an attachment (30) for the gas pipes and holder-side ports (11). The holder-side lid is movable between a connection position and a disconnection position, the connection position being a position in which the gas pipes and the holder-side ports are connected to device-side ports (21) of a device-side lid (25) of a cell cultivation device (20), the disconnection position being a position in which the connection is released.
In this X-ray imaging device (100), a control unit (10) generates a plurality of selection X-ray images (A1-A7, B1-B7, C1-C7, and D1-D7) having different viewing characteristics corresponding to a plurality of selection parameters extracted from a storage unit (7), sets a selection parameter used for the generation of a selected one selection X-ray image (D5) as an observation parameter (P1) for generating an observation X-ray image (I1), and stores the selection parameter in the storage unit (7).
A mass spectrometry device (10) comprises: an ion generation mechanism; an ion trap mechanism (140); a detector (150); and a voltage generation circuit (180). The ion trap mechanism captures ions in an internal space surrounded by a plurality of electrodes. The detector detects ions that have been discharged from the ion trap mechanism. The plurality of electrodes include: first electrodes (141) that generate an electric field for capturing ions; and second electrodes (142, 144) that, while the ions are being captured, generate an electric field for discharging specific ions from the ion trap mechanism. The voltage generation circuit includes: voltage sources (181, 182); switches (SW1, SW2); and resistance circuits (RC1, RC2). The voltage source (182) supplies a lower voltage than the voltage source (181). The switches (SW1, SW2) selectively supply the voltages from the voltage sources (181, 182) to the first electrode. The resistance circuits (RC1, RC2) are respectively connected to control terminals of the switches (SW1, SW2). Each of the resistance circuits has a variable resistance value.
This X-ray imaging device (100) is provided with: an optical imaging unit (31) for imaging an optical image (70); and an optical imaging control unit (32). The optical imaging control unit is configured to perform control for switching from a first mode to a second mode. The first mode is for displaying, with reference to a prescribed fixed position in a real space: an optical image on which is superimposed a region display (80) which includes at least one of a detection unit region display (81), an X-ray irradiation field region display (84), and an X-ray lighting field region display (87); or an optical image on which a region display is not superimposed. The second mode is for displaying an optical image on which is superimposed a region display that references a position on a body surface (101a) of a subject (101) in a real space.
G01N 30/26 - Conditioning of the fluid carrierFlow patterns
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This device comprises: an X-ray tube 11; an X-ray detector 9; an X-ray image generation unit 51; and an optical image capturing unit 29 arranged in an inspection room R1. The optical image capturing unit 29 includes: a housing 33; an opening 35 arranged on the housing 33; an optical lens 37 of a photographic camera 36 arranged inside the housing 33 so as to face the opening 35; and a shielding member 41 configured to be movable between a shielding position P1 and a retreat position P2 inside the housing 33 and capable of shielding the optical lens 37. The shielding member 41 is configured to shield the optical lens 37 so that the optical lens 37 cannot be visually recognized from the outside of the opening 35 in a state where the shielding member 41 is moved to the shielding position P1, and to enable the photographic camera 36 to capture an optical image through the opening 35 in a state where the shielding member 41 is moved to the retreat position P2.
This X-ray imaging system (100) is provided with: an X-ray irradiation unit (10); an X-ray detection unit (20) that detects X-rays; an optical imaging unit (31) that captures an image of an optical image (70) of a subject (101); a display unit (41); and a control unit (32) configured to cause a position reference image (90), which is disposed inside the X-ray detection unit (20) and indicates the position relative to the center of the X-ray detection unit (20), to be superimposed on the optical image (70) and displayed on the display unit (41).
This X-ray imaging device (100) comprises an optical imaging unit (30) and a control unit (32) that generates an enlarged partial image (3). The control unit (32) is configured such that, on the basis of the relationship between the optical axis (5) of the optical imaging unit (30) and an emission axis (6) of X-rays, the center position (3a) of the enlarged partial image (3) is shifted from the center position (2a) of an optical image (2) toward the position, in a real space, of the intersection (4) between an X-ray detection unit (20) and the emission axis (6) of X-rays emitted from an X-ray emission unit (10).
This X-ray imaging device (100) comprises a control unit (32) that calculates the distance (D1) between an X-ray tube (11) and a subject (101) on the basis of the coordinates of a prescribed position (33c) in an irradiation field region (33a) captured on the body surface of the subject (101) in an optical image (70) that is captured by an optical imaging unit (31).
A power supply that applies a tube voltage to a target includes a transformer, a switching circuit connected to a primary side of the transformer, and a substrate to which the switching circuit and the transformer are connected, the substrate including a first layer and a second layer. The transformer includes a first primary winding and a second primary winding on the primary side. A first wiring pattern that connects the first primary winding and the switching circuit to each other is located in the first layer. A second wiring pattern that connects the second primary winding and the switching circuit to each other is located in the second layer. The first layer and the second layer are arranged such that at least a part of the first wiring pattern overlaps with the second wiring pattern when the substrate is viewed from a stacked direction in a plan view.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
H01F 30/06 - Fixed transformers not covered by group characterised by the structure
H05G 1/10 - Power supply arrangements for feeding the X-ray tube
86.
METHOD FOR DETERMINING CHEMICAL STRUCTURE OF LIPID AND ION MOBILITY-TANDEM MASS SPECTROMETER
The present disclosure relates to the field of mass spectrometry, and particularly provides a method for determining a chemical structure of a lipid and an ion mobility-tandem mass spectrometer. The method for determining a chemical structure of a lipid includes: an ionization step of ionizing a sample to obtain sample ions; an ion mobility-based separation step of separating target lipid ions from the sample ions based on ion mobility; a first dissociation step of dissociating the target lipid ions with dissociation energy adjusted to break a first chemical bond of the target lipid ions; a mass-based selection step of selecting the target lipid ions, whose first chemical bond is broken, based on a mass number to obtain fragment ions; a second dissociation step of dissociating the fragment ions to at least break a second chemical bond of the fragment ions which has bond energy higher than the first chemical bond, to obtain diagnostic ions; and a mass analysis step of performing a mass analysis on the diagnostic ions.
An X-ray fluorescence spectrometer includes a first power supply that applies a tube voltage and a second power supply that supplies a filament current. The first power supply includes a switching circuit connected to a primary side of a transformer. The X-ray fluorescence spectrometer includes a current detection circuit connected to the primary side of the transformer to detect a current that flows to the primary side of the transformer and a control circuit that controls the first power supply based on the detected current. The current detection circuit includes a first comparator configured to detect whether or not the current detected by the current detection circuit is equal to or larger than a first threshold value. The control circuit detects occurrence of electric discharge based on detection of the current equal to or larger than the first threshold value by the current detection circuit.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01R 19/165 - Indicating that current or voltage is either above or below a predetermined value or within or outside a predetermined range of values
A mass spectrometer includes a mass filter, a wave-detection unit and a power supply device. The mass filter selects ions having a mass-to-charge ratio corresponding to an applied AC voltage. The wave-detection unit detects an AC voltage to be applied to the mass filter. The power supply device applies an AC voltage to the mass filter based on an AC voltage detected by the wave-detection unit. The wave-detection unit has a plurality of rectifiers. Each of the plurality of rectifiers includes a rectifying device. The plurality of rectifiers are electrically connected to one another in parallel.
A gas analysis system (1) includes a first flow channel (L1) through which sample gas that has passed through a column (41, 42) over helium gas as carrier gas flows, a second flow channel (L2) through which sample gas that has passed through a column (43, 44) over nitrogen gas as carrier gas flows, a TCD (90) that detects components in gas by making use of a difference in thermal conductivity among the components, and a switching module (M3). The switching module (M3) is arranged among the first flow channel (L1), the second flow channel (L2), and the TCD (90), and configured to switch between a first state in which the TCD (90) is connected to the first flow channel (L1) and a second state in which the TCD (90) is connected to the second flow channel (L2).
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01D 53/30 - Controlling by gas-analysis apparatus
A data processing method according to the present disclosure sets based on a first collection condition associated with a first separation condition, a second collection condition associated with a second separation condition. The data processing method according to the present disclosure includes calculating predicted retention time of each target component under the second separation condition, setting timings to start and quit collection of data under the second collection condition, and causing a chromatograph mass spectrometer to separate a sample under the second separation condition and to collect data on the target component under the second collection condition.
A gas analysis system (1) includes an inflow portion (C1) into which sample gas flows, a column (41, 42), a detector (50, 51) that detects a component in sample gas, a sampler module (M1) and a switching module (M2) including a plurality of valves (V1 to V10), and a controller (100) that independently controls the plurality of valves (V1 to V10). The controller (100) includes a storage (120) where function pattern information that defines correspondence between a plurality of basic functions and opening and closing patterns of the plurality of valves is stored and an output unit (110) that uses the function pattern information stored in the storage (120) to output control signals to the respective valves (V1 to V10).
The control device (100) controls the deflection amount (D2), which is the pressing amount, to a deflection amount (D1), which is a target value (DT), based on the set value (DS1, DS2) of the pressing amount when pressing the cantilever (12) against the sample (S) when measuring the force curve, and changing the set value (DS1) to the set value (DS2) based on the deflection amount (D3), which is differential data indicating the difference between the deflection amount (D1), which is the target value (DT), and the deflection amount (D), which is the actual pressing amount, in a previously performed force curve measurement when measuring the force curve.
This tube supporting plate includes a plate and a cover. The plate holds microtubes in a state in which a lid is not attached to an upper opening of a container body. The cover has formed therein through-holes corresponding to the container body, and the cover is disposed above a seal.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
This X-ray imaging device (100) is provided with: a holding unit (40) that holds an X-ray irradiation unit (10) so that the same can be moved in the horizontal direction; an optical imaging unit (30) that is provided to the holding unit (40); and a display unit (41) that is provided to the holding unit (40). The X-ray imaging device is configured so that a first display state of an optical image (2) displayed on the display unit (41) can be switched to a second display state in which the orientation of a subject (1) is rotated so as to match the orientation of the subject (1) in an X-ray image.
X-ray CT apparatus including an X-ray generation device and an X-ray detector that detects an X-ray emitted from the X-ray generation device and passing through an inspection object, and collecting X-ray projection data of at least two types of X-ray energies to reconstruct a dual energy image, the X-ray CT apparatus further includes: an acquisition unit that acquires inspection object information including a physical quantity and physical property information of the inspection object, and X-ray characteristic information of an X-ray spectrum, an X-ray filter, and the X-ray detector; and an X-ray imaging condition determination unit that determines X-ray imaging conditions for collecting X-ray projection data of the at least two types of X-ray energies emitted from the X-ray generation device, on the basis of the inspection object information and the X-ray characteristic information of the X-ray spectrum, the X-ray filter, and the X-ray detector acquired by the acquisition unit.
A method of measuring biological information according to the present disclosure is a measurement method of measuring biological information from a frame image group obtained by imaging over time of a subject. The method of measuring biological information according to the present disclosure divides a target region in each frame image included in the frame image group into a plurality of sub regions and extracts an amount of variation in each of the plurality of sub regions from the frame image group. The method of measuring biological information then determines sub regions similar in amount of variation from among the plurality of sub regions and obtains the biological information of the subject based on a summed value of the amount of variation in each of the similar sub regions.
The present disclosure relates to the field of mass spectrometry, and specifically to a method for identifying an unsaturated organic compound and a mass spectrometry system, which are particularly suitable for implementing position identification of a carbon-carbon double bond of an unsaturated lipid. The identification method includes a derivatization reaction step of aziridinating a carbon-carbon double bond in the unsaturated organic compound by an aza-Prilezhaev reaction to obtain a derivatization product, and then specifically dissociating the derivatization product, and performing mass analysis. Compared with the existing method, the identification method has at least one of the advantages of mild reaction conditions, minimal over-derivatization, minimal side reactions, and high conversion rate.
The objective of the present invention is to reduce the influence of disturbances acting on electromagnetic waves emitted toward an object. A measuring device (100) comprises a transmitting and receiving unit (11) and an information processing unit (15). The transmitting and receiving unit (11) emits primary electromagnetic waves toward a measurement target object (SA) and receives secondary electromagnetic waves returning from the measurement target object (SA). The information processing unit (15) calculates the moisture content of the measurement target object (SA) on the basis of the primary electromagnetic waves and the secondary electromagnetic waves.
G01N 22/00 - Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
This optical measuring device comprises a light source, an ultrasound wave source, a detector, a control device, and an analysis device. The control device acquires a first speckle image and a second speckle image on the basis of outputs of a detector acquired in a first imaging period and a second imaging period, causes laser light to be emitted in the first imaging period and the second imaging period, and causes oscillation of ultrasound waves from the ultrasound wave source such that the ultrasound waves reach a measuring position. The analysis device calculates a first variation component indicating an amount of variation of speckle in a first region and a second variation component indicating an amount of variation of speckle in a second region between the first speckle image and the second speckle image, and extracts a modulated signal component from the first variation component and the second variation component.
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
This optical measurement device comprises a light source, an ultrasonic wave source, an imaging device, a control device, and an analysis device. The control device causes the imaging device to image, during first to third imaging periods, signals of laser light that has passed through a region in a light scattering body, and controls imaging timings such that the interval between the first imaging period and the second imaging period and the interval between the second imaging period and the third imaging period are equal. The control device causes first laser light, second laser light, and third laser light to be respectively emitted from the light source during the first imaging period, the second imaging period, and the third imaging period, and causes ultrasonic waves to be generated from the ultrasonic wave source at the emission timing of the third laser light such that the ultrasonic waves arrive at a measurement location. The analysis device extracts modulated signal components by using a signal of the first laser light, a signal of the second laser light, and a signal of the third laser light, which have passed through the region in the light scattering body.
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
