Abstract

Systems and methods for producing liposomes, including control liposomes and immunoliposomes targeting breast cancer are provided. Systems and methods for treating breast cancer, using targeted immunoliposomes produced according to various methods are also disclosed herein. For example, trastuzumab-conjugated immunoliposomes may be used to deliver chemotherapeutic agents to breast cancer tissues for the treatment of breast cancer. Systems and methods for actuating liposomes using ultrasound are also disclosed, such as systems and methods for actuating trastuzumab-conjugated liposomes accumulated in breast cancer tissues for the treatment of breast cancer.

IPC Classes  ?

• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61P 35/00 - Antineoplastic agents

Abstract

There is disclosed a conductive concrete structure for electromagnetic shielding comprising a first planar surface; a metal mesh positioned on a first face of the first planar surface; and cast concrete positioned on or around the metal mesh. There is also disclosed a method of assembling a conductive concrete structure for electromagnetic shielding. The method comprises positioning a metal mesh comprising a plurality of metal wires on a first planar surface and casting concrete on the metal mesh.

IPC Classes  ?

• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields
• C04B 14/48 - Metal
• C04B 18/14 - Waste materialsRefuse from metallurgical processes
• C04B 28/00 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
• E04B 1/92 - Protection against other undesired influences or dangers

Abstract

In some implementations, a conductive concrete composition for providing improved shielding against electromagnetic radiation comprises cement, one or more supplementary materials, aggregates, one or more carbon products, and fibers. In some implementations, the composition comprises between about 5% and about 40% by weight of cement, between about 1% and about 20% by weight of one or more supplementary materials, between about 5% and about 80% by weight of aggregates, between about 1% and about 40% by weight of one or more carbon products, and between about 1% and about 10% by weight of fibers. In some embodiments, the one or more supplementary materials comprises ground granulated blast furnace slag (GGBS), the one or more carbon products comprises graphite, and the fibers comprise steel fibers. The aggregates can include normal weight, lightweight, and/or fine aggregates.

IPC Classes  ?

• E04B 1/04 - Structures consisting primarily of load-supporting, block-shaped or slab-shaped elements the elements consisting of concrete, e.g. reinforced concrete, or other stone-like material
• C04B 28/08 - Slag cements
• C04B 14/02 - Granular materials
• C04B 14/48 - Metal
• E04B 1/92 - Protection against other undesired influences or dangers

Abstract

A fin device with a housing that receives a camera to capture an underwater view. The fin device includes a fin that extends from a bottom surface of a water transportation device, such as a windsurf board, boat, surf board, or the like. The housing can be integrated with the fin and have a removable cap to allow access into a cavity that is sized and shaped to receive the camera. The camera can capture a view through the removable cap while securely retained within the housing.

IPC Classes  ?

• B63B 32/60 - Board appendages, e.g. fins, hydrofoils or centre boards
• B60R 11/04 - Mounting of cameras operative during driveArrangement of controls thereof relative to the vehicle
• B63B 32/70 - Accessories not specially adapted for a particular type of board, e.g. paddings or buoyancy elements

Abstract

In some implementations, a conductive concrete composition for providing improved shielding against electromagnetic radiation comprises cement, one or more supplementary materials, aggregates, one or more carbon products, and fibers. In some implementations, the composition comprises between about 5% and about 40% by weight of cement, between about 1% and about 20% by weight of one or more supplementary materials, between about 5% and about 80% by weight of aggregates, between about 1% and about 40% by weight of one or more carbon products, and between about 1% and about 10% by weight of fibers. In some embodiments, the one or more supplementary materials comprises ground granulated blast furnace slag (GGBS), the one or more carbon products comprises graphite, and the fibers comprise steel fibers. The aggregates can include normal weight, lightweight, and/or fine aggregates.

IPC Classes  ?

• C04B 14/02 - Granular materials
• C04B 18/14 - Waste materialsRefuse from metallurgical processes
• C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
• E04B 2/18 - Walls having cavities in, but not between, the elements, i.e. each cavity being enclosed by at least four sides forming part of one single element using elements having specially designed means for stabilising the position by interlocking of projections or inserts with indentations, e.g. of tongues, grooves, dovetails
• E04C 2/04 - Building elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by specified materials of concrete or other stone-like materialBuilding elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by specified materials of asbestos cement
• E04C 2/52 - Building elements of relatively thin form for the construction of parts of buildings, e.g. sheet materials, slabs, or panels characterised by the shape or structure with special adaptations for auxiliary purposes, e.g. serving for locating conduits
• E04B 1/343 - Structures characterised by movable, separable, or collapsible parts, e.g. for transport
• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields

Abstract

Systems and methods for producing liposomes, including control liposomes and immunoliposomes targeting breast cancer are provided. Systems and methods for treating breast cancer, using targeted immunoliposomes produced according to various methods are also disclosed herein. For example, trastuzumab-conjugated immunoliposomes may be used to deliver chemotherapeutic agents to breast cancer tissues for the treatment of breast cancer. Systems and methods for actuating liposomes using ultrasound are also disclosed, such as systems and methods for actuating trastuzumab-conjugated liposomes accumulated in breast cancer tissues for the treatment of breast cancer.

IPC Classes  ?

• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61P 35/00 - Antineoplastic agents
• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation

Abstract

An integrated sanitary unit that can be used for washing portions of the body at locations such as factories, warehouses, gymnasiums, places of worship, and others. The unit can be used to perform the Muslim ablution ritual. The unit can have multiple faucets at different positions to accommodate washing upper and lower portions of a user's body. The unit can have multiple foot supports to support a user's foot while washing. The unit can have single or multiple hand grips that a user can grasp for support. The unit can have a sink to collect and drain fluid used to wash upper portions of the user's body. The unit can enable a user to perform the Muslim ablution ritual in a comfortable, safe, and hygienic manner. The unit can be conveniently installed on a wall or other support element inside or outside of an ablution space.

IPC Classes  ?

• A47K 3/022 - Baths specially adapted for particular use, e.g. for washing the feet, for bathing in sitting position
• A47K 1/02 - Portable toilet tablesWash cabinets or stands
• A47K 1/08 - Accessories for toilet tables, e.g. glass plates, supports therefor
• A47K 3/062 - Collapsible baths specially adapted for particular use, e.g. for washing the feet, for bathing in sitting position
• A47K 4/00 - Combinations of baths, showers, sinks, wash-basins, closets, or urinals, not covered by a single other group of this subclass
• E03C 1/01 - Domestic plumbing installations for fresh water or waste waterSinks for combinations of baths, showers, sinks, wash-basins, closets, urinals, or the like
• E03C 1/322 - Holders or supports for basins connected to the wall only

Abstract

Aspects of this disclosure relate to a miniaturized digital radar system and method that can be fabricated on a Printed Circuit Board (PCB) and/or a chip, such as on a System-On-a-Chip (SOC). The digital radar system can operate at the S-band (e.g. in the range of 3 GHz). Advantageously, the S-band frequency range is less susceptible and/or not susceptible to clutter from precipitation and is well suited for long range surveillance applications. The small form factor of the miniaturized digital radar system on the PCB and/or the SOC can be implemented on small and/or low-observable platforms, such as on fixed or rotary wing unmanned aerial vehicles.

IPC Classes  ?

• G01S 7/03 - Details of HF subsystems specially adapted therefor, e.g. common to transmitter and receiver
• G01S 13/02 - Systems using reflection of radio waves, e.g. primary radar systemsAnalogous systems
• G01S 13/48 - Indirect determination of position data using multiple beams at emission or reception
• H04B 1/44 - Transmit/receive switching
• H04L 25/02 - Baseband systems Details
• H04B 1/40 - Circuits
• H04B 1/3827 - Portable transceivers
• H04B 1/38 - Transceivers, i.e. devices in which transmitter and receiver form a structural unit and in which at least one part is used for functions of transmitting and receiving
• H01Q 21/06 - Arrays of individually energised antenna units similarly polarised and spaced apart

Abstract

Aspects of this disclosure relate to a miniaturized digital radar system and method that can be fabricated on a Printed Circuit Board (PCB) and/or a chip, such as on a System-On-a-Chip (SOC). The digital radar system can operate at the S-band (e.g. in the range of 3 GHz). Advantageously, the S-band frequency range is less susceptible and/or not susceptible to clutter from precipitation and is well suited for long range surveillance applications. The small form factor of the miniaturized digital radar system on the PCB and/or the SOC can be implemented on small and/or low-observable platforms, such as on fixed or rotary wing unmanned aerial vehicles.

IPC Classes  ?

• G01S 13/02 - Systems using reflection of radio waves, e.g. primary radar systemsAnalogous systems
• G01S 13/66 - Radar-tracking systemsAnalogous systems
• G01S 7/285 - Receivers

Abstract

The invention relates to a device for use in histological processes to support a microscope slide during the mounting of a tissue section, where the device includes a container for receiving a buffer solution and tissue sections, a platform located in a contactless manner within the container for receiving a microscope slide on which to mount the sections and a lifting arrangement for moving the platform relative to the container and, in and out of the buffer solution.

IPC Classes  ?

• G02B 21/34 - Microscope slides, e.g. mounting specimens on microscope slides
• G01N 1/28 - Preparing specimens for investigation

Abstract

Systems and methods for producing liposomes, including control liposomes and immunoliposomes targeting breast cancer are provided. Systems and methods for treating breast cancer, using targeted immunoliposomes produced according to various methods are also disclosed herein. For example, trastuzumab-conjugated immunoliposomes may be used to deliver chemotherapeutic agents to breast cancer tissues for the treatment of breast cancer. Systems and methods for actuating liposomes using ultrasound are also disclosed, such as systems and methods for actuating trastuzumab-conjugated liposomes accumulated in breast cancer tissues for the treatment of breast cancer.

IPC Classes  ?

• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61P 35/00 - Antineoplastic agents
• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation

Abstract

This invention provides a way of classifying bughole rating of concrete surfaces. The apparatus uses air leakage method for classification and rating of bugholes on the surface of concrete (6) and comprises of an air pump (1), differential pressure sensor (3), measurement electronics (5) and resiliently flexible skirt (4) that comes in contact with the concrete surface (6). Air pumped by the pump (1) fills the internal cavity (2) which leaks through the bugholes that skirt lip crosses over. The air pressure inside the cavity (2) indicates the amount and the size of the bugholes on the concrete surface (6).

IPC Classes  ?

• G01B 13/22 - Measuring arrangements characterised by the use of fluids for measuring roughness or irregularity of surfaces
• G01N 33/38 - ConcreteLimeMortarGypsumBricksCeramicsGlass