Thermo Fisher Scientific Inc.

United States of America

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IPC Class
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light 5
B01D 35/18 - Heating or cooling the filters 2
B01D 53/56 - Nitrogen oxides 2
C02F 1/02 - Treatment of water, waste water, or sewage by heating 2
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical 2
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Status
Pending 3
Registered / In Force 49
Found results for  patents

1.

Fluid transfer device

      
Application Number 29858917
Grant Number D1064312
Status In Force
Filing Date 2022-11-04
First Publication Date 2025-02-25
Grant Date 2025-02-25
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Chae, Ken S.

2.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29933258
Grant Number D1054449
Status In Force
Filing Date 2024-03-19
First Publication Date 2024-12-17
Grant Date 2024-12-17
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

3.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29933269
Grant Number D1054450
Status In Force
Filing Date 2024-03-19
First Publication Date 2024-12-17
Grant Date 2024-12-17
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

4.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29920405
Grant Number D1054447
Status In Force
Filing Date 2023-12-11
First Publication Date 2024-12-17
Grant Date 2024-12-17
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

5.

FLUID TRANSFER DEVICE AND ASSOCIATED SYSTEM

      
Application Number 18787210
Status Pending
Filing Date 2024-07-29
First Publication Date 2024-11-21
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Chae, Ken S.
  • Makinen, Mikko Antero

Abstract

A fluid transfer device that aspirates and dispenses fluid without a user needing to directly actuate the fluid transfer device by being actuated for aspiration when inserted into a device such as a vial or for dispensing when inserted into a receiving device such as a cassette. In embodiments, the cassette is designed as part of a system with the fluid transfer device which securely attaches to the cassette when dispensing a fluid sample.

IPC Classes  ?

6.

Method And Composition For Multiplexed And Multimodal Single Cell Analysis

      
Application Number 18254135
Status Pending
Filing Date 2021-12-09
First Publication Date 2024-05-30
Owner
  • Thermo Fisher Scientific Inc. (USA)
  • Phitonex, Inc. (USA)
Inventor
  • Stadnisky, Michael
  • Laboda, Craig
  • Pinkin, Nicholas
  • Godinez, Ivan

Abstract

Provided herein are multimodal methods and compositions that combine sequence-tagged antibodies and fluorescent labels in a single reagent. Combined with optimal panel design, high-purity sorting of cells before sequencing has been demonstrated, and furthermore, truly quantitative information on the cell surface markers used for sorting.

IPC Classes  ?

7.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29870225
Grant Number D1020784
Status In Force
Filing Date 2023-01-19
First Publication Date 2024-04-02
Grant Date 2024-04-02
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

8.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29870227
Grant Number D1020785
Status In Force
Filing Date 2023-01-19
First Publication Date 2024-04-02
Grant Date 2024-04-02
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

9.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29870218
Grant Number D1007525
Status In Force
Filing Date 2023-01-19
First Publication Date 2023-12-12
Grant Date 2023-12-12
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

10.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29713610
Grant Number D0980233
Status In Force
Filing Date 2019-11-18
First Publication Date 2023-03-07
Grant Date 2023-03-07
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

11.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29713612
Grant Number D0980234
Status In Force
Filing Date 2019-11-18
First Publication Date 2023-03-07
Grant Date 2023-03-07
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

12.

Methods and Compositions for Selecting siRNA of Improved Functionality

      
Application Number 17520530
Status Pending
Filing Date 2021-11-05
First Publication Date 2022-10-06
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Khvorova, Anastasia
  • Reynolds, Angela
  • Leake, Devin
  • Marshall, William
  • Read, Steven
  • Scaringe, Stephen

Abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.

IPC Classes  ?

  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy

13.

Collaborative virtual reality environment for training

      
Application Number 17251848
Grant Number 11614849
Status In Force
Filing Date 2019-05-13
First Publication Date 2021-08-19
Grant Date 2023-03-28
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • Field, Mark
  • Garden, Daniel

Abstract

A system including a display output device, a computer including instructions that when executed by the computer, cause the computer to generate a virtual environment, instantiate one or more virtual devices into the virtual environment, instantiate a user representation into the virtual environment, and display the virtual environment, the one or more virtual devices, and the user representation on the display output device, an input device to receive a movement input associated with movement by the user representation in the virtual environment, and the computer further configured with instructions to move or rotate the one or more virtual devices relative to a point of reference in the virtual environment in response to the movement input, while maintaining the user representation stationary.

IPC Classes  ?

  • G06F 3/04815 - Interaction with a metaphor-based environment or interaction object displayed as three-dimensional, e.g. changing the user viewpoint with respect to the environment or object
  • G06F 21/46 - Structures or tools for the administration of authentication by designing passwords or checking the strength of passwords
  • G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
  • G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
  • G06T 19/00 - Manipulating 3D models or images for computer graphics
  • G06F 3/04845 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range for image manipulation, e.g. dragging, rotation, expansion or change of colour

14.

System and method for rapid and accurate trace gas measurement

      
Application Number 16687903
Grant Number 11674847
Status In Force
Filing Date 2019-11-19
First Publication Date 2020-05-21
Grant Date 2023-06-13
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Li, Yongquan
  • Lopes, Corsino

Abstract

An embodiment of a system for measuring trace gas concentration is described that comprises a laser absorption spectrometer configured to detect an absorbance measure from a trace gas, as well as a temperature value and a pressure value that correspond to an environment in a gas cell; and a computer having executable code stored thereon configured to perform a method comprising: receiving the absorbance value, the temperature value, and the pressure value; defining a fitting range associated with the trace gas; applying a curve fitting model in the fitting range to the absorbance value using the temperature value and the pressure value as model parameters; and producing a concentration measure of the trace gas.

IPC Classes  ?

  • G01J 3/10 - Arrangements of light sources specially adapted for spectrometry or colorimetry
  • G01N 21/39 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
  • G01J 3/433 - Modulation spectrometryDerivative spectrometry
  • G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis

15.

Display screen of a biological safety cabinet with graphical user interface

      
Application Number 29613296
Grant Number D0870739
Status In Force
Filing Date 2017-08-09
First Publication Date 2019-12-24
Grant Date 2019-12-24
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Van Guilder, Krista Lyn
  • Phillips, David Scott

16.

System and method for an interrupt mode ion chamber

      
Application Number 15992764
Grant Number 10809392
Status In Force
Filing Date 2018-05-30
First Publication Date 2018-12-20
Grant Date 2020-10-20
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Poon, King L.
  • Esin, Alexander Joseph
  • Kulik, Alexei
  • Xing, Huichun

Abstract

An embodiment of a system is described that comprises an ionization chamber electrically coupled with a charge amplifier circuit by a reed switch. The reed switch of the embodiments described herein produces substantially no leakage current and electrically insulates the charge amplifier from the ionization chamber.

IPC Classes  ?

  • G01T 1/185 - Measuring radiation intensity with ionisation-chamber arrangements
  • G01T 1/17 - Circuit arrangements not adapted to a particular type of detector

17.

Explosives vapor detector

      
Application Number 06732449
Grant Number 10113983
Status In Force
Filing Date 1985-05-09
First Publication Date 2018-10-30
Grant Date 2018-10-30
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Fine, David H.
  • Fraim, Freeman W.
  • Buckley, James E.

Abstract

14. Airborne explosives vapors are selectively adsorbed on a spiral-wound platinum or platinum-coated ribbon of a preconcentrator cartridge while trapping of nitrogen oxides is avoided. The vapors are released and partially decomposed to liberate nitric oxide gas by flash-heating of the ribbon, these products may then be pyrolyzed if necessary to complete the liberation of nitric oxide gas, and then the liberated nitric oxide gas is detected, as by chemiluminescent detection. Also described are various systems incorporating the explosives vapor detector such as a walk-through portal, a vehicle sniffer, and a system incorporated into the air-handling apparatus of a building. A walk-through explosives detection system is disclosed having a carousel containing an array of preconcentrator cartridges for rapid acquisition and analysis of explosives vapor samples, and which is capable of screening up to ten persons per minute for possession of explosives.

IPC Classes  ?

  • G01N 1/02 - Devices for withdrawing samples
  • G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance

18.

Tamper seal detection system with conveyor belt and method of use

      
Application Number 15421721
Grant Number 10035617
Status In Force
Filing Date 2017-02-01
First Publication Date 2018-07-31
Grant Date 2018-07-31
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor Shipp, Martin

Abstract

A method for detecting sealing stickers on a packaging box includes placing a first packaging box onto a conveyor belt of a conveyor belt system at an inspection zone, the first packaging box having a first sealing sticker thereon that at least partially seals the first packaging box closed; and activating a first optical sensor to detect whether the first sealing sticker is located on a first side of the first packaging box while the packaging box is in the inspection zone.

IPC Classes  ?

  • B61L 1/16 - Devices for counting axlesDevices for counting vehicles
  • B65B 57/18 - Automatic control, checking, warning or safety devices causing operation of audible or visible alarm signals
  • B65B 7/20 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by folding-down preformed flaps
  • G01V 8/10 - Detecting, e.g. by using light barriers

19.

Tamper seal detection system and method of use

      
Application Number 15786238
Grant Number 10288555
Status In Force
Filing Date 2017-10-17
First Publication Date 2018-04-26
Grant Date 2019-05-14
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • Kerschner, Cody T.
  • Heaps, Christian S.
  • Tomel, Justin J.
  • Regits, Shawn M.

Abstract

A tamper seal detection system for detecting a sealing sticker on a packaging box includes a housing at least partially bounding an inspection zone, the inspection zone being configured to receive the packaging box. A first sensor is configured to detect the presence of the first sealing sticker located on the packaging box when the packaging box is received within the inspection zone. A push guide is movable relative to the inspection floor between a first position and a spaced apart second position and can be used to push the packaging box out of the inspection zone.

IPC Classes  ?

  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
  • G01N 21/29 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
  • B65D 55/02 - Locking devicesMeans for discouraging or indicating unauthorised opening or removal of closure
  • G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
  • G01N 21/63 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
  • G09F 3/00 - Labels, tag tickets, or similar identification or indication meansSealsPostage or like stamps
  • G09F 3/03 - Forms or constructions of security seals
  • B07C 5/00 - Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or featureSorting by manually actuated devices, e.g. switches
  • B65B 51/00 - Devices for, or methods of, sealing or securing package folds or closures, e.g. twisted bag necks
  • B65B 57/00 - Automatic control, checking, warning or safety devices
  • G01N 21/90 - Investigating the presence of flaws, defects or contamination in a container or its contents
  • G01N 21/956 - Inspecting patterns on the surface of objects

20.

Fluid density meters auto-start by injection seed vibration using frequency scanning method

      
Application Number 14958147
Grant Number 10006844
Status In Force
Filing Date 2015-12-03
First Publication Date 2016-06-09
Grant Date 2018-06-26
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Bakhirkin, Yury A.
  • Esin, Alexander Joseph
  • Li, Yanzhong

Abstract

A method of initiating a fluid density measurement includes generating a prime resonance of a test fixture by a startup circuit. The method of initiating a fluid density measurement includes closing a feedback loop in response to generating the prime resonance. The method of initiating a fluid density measurement includes maintaining the prime resonance by closing the feedback loop.

IPC Classes  ?

  • G01N 9/00 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity
  • G01N 9/34 - Investigating density or specific gravity of materialsAnalysing materials by determining density or specific gravity by using flow properties of fluids, e.g. flow through tubes or apertures by using elements moving through the fluid, e.g. vane

21.

Ultra-high speed imaging array with orthogonal readout architecture

      
Application Number 13648741
Grant Number 08829409
Status In Force
Filing Date 2012-10-10
First Publication Date 2014-04-10
Grant Date 2014-09-09
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Wadsworth, Mark

Abstract

A plurality of unit pixels in a two dimensional imaging array are arranged in a manner that signal charges along a given row are added to other relevant signal charges of the same row. Signal charges along a given column are added to other relevant signal charges of the same column. Summed charge values are output simultaneously from rows and columns to produce one row and one column of image data. The resulting summed data is temporarily stored in on-chip buffers and then output from the chip during the integration time of the next imaging cycle with no loss in imaging duty cycle.

IPC Classes  ?

  • H01L 27/00 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
  • H04N 3/14 - Scanning details of television systemsCombination thereof with generation of supply voltages by means not exclusively optical-mechanical by means of electrically scanned solid-state devices

22.

Mercury monitoring system and reaction chamber for enhancing conversion of elemental mercury gas into oxidized mercury

      
Application Number 12764642
Grant Number 08609045
Status In Force
Filing Date 2010-04-21
First Publication Date 2013-12-17
Grant Date 2013-12-17
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Kita, Dieter
  • Socha, Jeffrey
  • Marcotte, Bryan A.

Abstract

A reaction chamber enables a reaction between received elemental mercury gas and an oxidizing agent gas. The reaction chamber includes a porous (or permeable) medium through which to pass the elemental mercury gas and the oxidizing agent gas. Passing of the elemental mercury gas and the oxidizing agent gas through the porous medium supports a number of useful functions. For example, the porous medium enhances mixing of the elemental mercury gas with the oxidizing agent gas to enhance a reaction. Also, the porous medium increases an amount of surface area in a reaction chamber on which reactions (e.g., heterogeneous surface reactions) can take place between the elemental mercury gas and the oxidizing agent gas to form oxidized mercury gas. Accordingly, the reaction chamber configured to include a porous medium enhances a conversion of elemental mercury gas into oxidized mercury gas.

IPC Classes  ?

  • B01D 47/00 - Separating dispersed particles from gases, air or vapours by liquid as separating agent
  • B01D 53/46 - Removing components of defined structure
  • B01D 53/56 - Nitrogen oxides
  • B01D 53/86 - Catalytic processes
  • B01J 8/00 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes
  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
  • G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
  • G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
  • G01N 37/00 - Details not covered by any other group of this subclass

23.

Measurement of sulfur trioxide via spectroscopy

      
Application Number 12693293
Grant Number 08368896
Status In Force
Filing Date 2010-01-25
First Publication Date 2013-02-05
Grant Date 2013-02-05
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Li, Yongquan
  • Socha, Jeffrey S.
  • Kita, Dieter

Abstract

−1. The optical signal is transmitted along an optical path through the gas sample. Based on adjusting a pressure of the gas sample, each of the plurality of vibration-rotation absorption transitions associated with the sulfur trioxide can be substantially isolated from interfering absorption by the sulfur dioxide and the water vapor in the gas sample. Based on a spectral analysis, the system generates a value indicative of a concentration of sulfur trioxide in the gas sample.

IPC Classes  ?

  • G01B 11/00 - Measuring arrangements characterised by the use of optical techniques
  • F23N 5/08 - Systems for controlling combustion using devices responsive to thermal changes or to thermal expansion of a medium using light-sensitive elements

24.

Low maintenance reference electrode for electrochemical measurements

      
Application Number 13455727
Grant Number 08840767
Status In Force
Filing Date 2012-04-25
First Publication Date 2012-08-16
Grant Date 2014-09-23
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • Wen, Xiaowen
  • Yim, Hyoungsik
  • Hrdy, Lori
  • Bhaijee, Dawood

Abstract

A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.

IPC Classes  ?

25.

Generation of sulfur trioxide and sulfuric acid

      
Application Number 13251754
Grant Number 08679435
Status In Force
Filing Date 2011-10-03
First Publication Date 2012-04-12
Grant Date 2014-03-25
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Kita, Dieter
  • Li, Yongquan
  • Socha, Jeffrey
  • Marcotte, Bryan A.

Abstract

Configurations herein include a novel process and apparatus for generating and maintaining sulfur trioxide gas. The generation system and process operate to provide sulfur trioxide calibration gas for calibrating sulfur trioxide detection devices. The system and process provides a known, concentration of sulfur trioxide gas via a heated catalyst, which enables accurate calibration of measurement equipment. The system functions in part by controlling temperature, amount of moisture, residence time, catalyst selection, diluting generated sulfur trioxide and by locating the sulfur trioxide generator at a point of injection of a sulfur trioxide detection system.

IPC Classes  ?

  • B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
  • B01D 53/56 - Nitrogen oxides
  • C01B 17/00 - SulfurCompounds thereof
  • C01B 17/74 - Preparation

26.

Increase of neutron flux with gamma shielding

      
Application Number 12852032
Grant Number 08384018
Status In Force
Filing Date 2010-08-06
First Publication Date 2012-02-09
Grant Date 2013-02-26
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Esin, Alexander Joseph
  • Baturin, Nikolay
  • Kulik, Alex
  • Brosseau, Michael G.

Abstract

An analyzer having a detector and a neutron source assembly adjacent to the detector is disclosed, wherein the neutron source assembly has a neutron source and a shielding source holder.

IPC Classes  ?

  • G01V 5/10 - Prospecting or detecting by the use of ionising radiation, e.g. of natural or induced radioactivity specially adapted for well-logging using primary nuclear radiation sources or X-rays using neutron sources

27.

Method for detecting high-energy radiation using low voltage optimized ion chamber

      
Application Number 12852347
Grant Number 08415638
Status In Force
Filing Date 2010-08-06
First Publication Date 2012-02-09
Grant Date 2013-04-09
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Esin, Alexander Joseph
  • Kulik, Alex
  • Baturin, Nikolay

Abstract

A method for measuring high-energy radiation flux, comprising applying a low voltage to electrodes in an ion chamber filled with a fluid capable of forming ions through the interaction of the fluid with high energy radiation; measuring an ion current signal related to an ion current induced by the low voltage; determining a leakage current; determining a gain; determining a magnitude of the high-energy radiation flux based on the ion current signal, gain, and leakage current; and outputting the result of the magnitude of the high-energy radiation flux.

IPC Classes  ?

  • G01T 1/185 - Measuring radiation intensity with ionisation-chamber arrangements

28.

Particulate matter monitor

      
Application Number 13103796
Grant Number 08726720
Status In Force
Filing Date 2011-05-09
First Publication Date 2011-11-10
Grant Date 2014-05-20
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Goohs, Kevin J.
  • Socha, Jeffrey

Abstract

A particulate monitoring system includes a conduit in which to a pass a fluid sample from an input port to an output port. The particulate monitoring system receives a fluid sample inputted to the conduit through the input port. The fluid sample can include different sizes of particulate matter. The particulate monitoring system controls a flow of the fluid sample through the conduit to age the particulate matter. Gravitational forces cause a portion of the particulate matter in the fluid sample to fall into a basin as opposed to being exhausted through the output port, which is disposed at a vertically higher level of the conduit than the input port. Thus, the particulate monitoring system outputs a portion of the original particulate matter in the fluid sample (e.g., particulate matter that does not drop into the basin out due to gravity) for analysis.

IPC Classes  ?

  • G01N 15/06 - Investigating concentration of particle suspensions

29.

Gas inlet for a process mass spectrometer

      
Application Number 12769295
Grant Number 08847156
Status In Force
Filing Date 2010-04-28
First Publication Date 2011-11-03
Grant Date 2014-09-30
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Josland, Graham David

Abstract

An inlet for a process mass spectrometer, the inlet comprising, a capillary in fluid communication with a sample gas feed; a transfer line in fluid communication to the capillary; a first orifice configured to generate a change in pressure, the orifice comprising at least two measuring ports; a pressure sensor operatively connected to at least one of the two measuring ports; and a second transfer line in fluid communication with the first orifice, the second transfer line also in fluid communication with an external disposal point.

IPC Classes  ?

  • H01J 49/00 - Particle spectrometers or separator tubes
  • H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components

30.

Temperature compensation for ion-selective electrodes

      
Application Number 12692740
Grant Number 08287705
Status In Force
Filing Date 2010-01-25
First Publication Date 2011-07-28
Grant Date 2012-10-16
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • Hirshberg, Moshe
  • Wen, Xiaowen
  • Yim, Hyoungsik
  • Bhaijee, Dawood

Abstract

Temperature compensation for ion-selective electrodes is obtained by positioning a temperature-measuring element in a chamber of limited thermal mass which is in thermal contact with the measuring electrode filling solution but is thermally isolated from other filling solutions in the electrode. In a preferred embodiment, the temperature-measuring element comprises a thermistor enclosed within thin flexible tubing; the electrical leads of the thermistor are forced against a segment of the inner wall of the tubing by an elongated strand of material abutting the thermistor to enhance heat transfer with the thermistor.

IPC Classes  ?

31.

Particulate detection and calibration of sensors

      
Application Number 12777127
Grant Number 08351035
Status In Force
Filing Date 2010-05-10
First Publication Date 2010-12-16
Grant Date 2013-01-08
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Goohs, Kevin J.
  • Lilienfeld, Pedro
  • Kita, Dieter
  • Hiss, John G.

Abstract

According to example configurations herein, a fluid sample flow including particulate matter passes through a conduit. One or more optical sensors monitor optical energy scattering off of the particulate matter in the fluid sample flow as it passes through the conduit. A magnitude of the optical energy sensed by the one or more optical sensors varies depending on particulate matter present in the fluid sample flow. An analyzer monitors the magnitude of the optical energy sensed by the one or more optical sensors and detects changes in the optical energy. A change in the optical energy can indicate a change in the particulate matter present in the fluid sample flow. In response to detecting the change in the optical energy, the analyzer initiates one or more functions such as recalibration, purging, execution of diagnostics, etc.

IPC Classes  ?

  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light

32.

Methods for detecting particles in aerosol gas streams

      
Application Number 12824726
Grant Number 08194234
Status In Force
Filing Date 2010-06-28
First Publication Date 2010-10-21
Grant Date 2012-06-05
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Hopke, Philip Karl
  • Ambs, Jeffrey Lawrence

Abstract

Turbulent mixing condensation devices, methods, and systems adapted to condense a working fluid on particles from a sample gas to enlarge the particles for subsequent detection are provided. The device includes a vapor generator adapted to produce a working-fluid saturated carrier gas and a condensation chamber. The working-fluid saturated carrier gas is mixed with a sample gas containing particles to be detected and is then introduced to the condensation chamber. The operating conditions are controlled to enhance the condensation of the working fluid on the particles. The particles are typically forwarded to a particle detection device to detect at least one characteristic, for example, the size, of the particles. The flow of carrier gas to the vapor generator may be regulated to vary the degree of saturation of the carrier gas with working fluid.

IPC Classes  ?

  • G01N 37/00 - Details not covered by any other group of this subclass

33.

Bulk material analyzer assembly including structural beams containing radiation shielding material

      
Application Number 12376839
Grant Number 08138480
Status In Force
Filing Date 2007-08-10
First Publication Date 2010-07-01
Grant Date 2012-03-20
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Proctor, Raymond John
  • Lucchin, Anton Mario
  • Atwell, Thomas Leland
  • Chiesman, Mark Rudy

Abstract

A bulk material analyzer (FIG. 2) is variably constructed from an assembly of components The analyzer (FIG. 2) is the type that is used to analyze bulk material (28) transported on a conveyor belt (29) through an activation region (30) between at least one radiation source (element 11) and at least one radiation detector (12) within the bulk material analyzer (FIG. 2) The assembly includes a radiation-source box (11) for disposition either above the activation region (30) or below the conveyor belt (29), a radiation-detector box (12) for disposition on the opposite side of the activation region (30) and the conveyor belt (29) from the radiation-source box (11); and a set of stackable structural beams (14, 15, 16, 17, 18, 19) predominantly containing radiation shielding material and configured for stacking about the activation region (30), the radiation-source box (11) and the radiation-detector box (12) to prevent unwanted radiation being generated and transported to the radiation-detector box (12).

IPC Classes  ?

  • G01N 23/222 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by activation analysis using neutron activation analysis [NAA]

34.

Mercury monitoring system and reaction chamber for enhancing conversion of elemental mercury gas into oxidized mercury

      
Application Number 11818664
Grant Number 07736602
Status In Force
Filing Date 2007-06-14
First Publication Date 2010-06-15
Grant Date 2010-06-15
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Kita, Dieter
  • Socha, Jeffrey
  • Marcotte, Bryan A.

Abstract

A reaction chamber enables a reaction between received elemental mercury gas and an oxidizing agent gas. The reaction chamber includes a porous (or permeable) medium through which to pass the elemental mercury gas and the oxidizing agent gas. Passing of the elemental mercury gas and the oxidizing agent gas through the porous medium supports a number of useful functions. For example, the porous medium enhances mixing of the elemental mercury gas with the oxidizing agent gas to enhance a reaction. Also, the porous medium increases an amount of surface area in a reaction chamber on which reactions (e.g., heterogeneous surface reactions) can take place between the elemental mercury gas and the oxidizing agent gas to form oxidized mercury gas. Accordingly, the reaction chamber configured to include a porous medium enhances a conversion of elemental mercury gas into oxidized mercury gas.

IPC Classes  ?

  • B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light

35.

Vapor analysis apparatus and method

      
Application Number 10617588
Grant Number 07588726
Status In Force
Filing Date 2003-07-11
First Publication Date 2009-09-15
Grant Date 2009-09-15
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Mouradian, Robert F.
  • Kennedy, Patrick John
  • Johnson, Jr., K. Stephen

Abstract

A vapor analysis system comprising a vapor analyzer capable of collecting and analyzing a vapor sample for detection of a compound that may be contained within the vapor sample. A controller is coupled to the vapor analyzer. The controller is programmed to produce an indicator signal indicative of a relative concentration of the compound detected by the vapor analyzer within the vapor sample. A sample probe includes a housing containing a vapor channel through which the vapor sample is collected, and a vapor cable couples the sample probe to the vapor analyzer to allow collection and channeling of the vapor sample to the vapor analyzer. A multi-dimensional user indicator is disposed on the housing of the sample probe receives and operates in response to the indicator signal to indicate the relative concentration of the compound detected within the vapor sample for presentation via a multi-directional stimulus to a user of the vapor analysis system. Users are able to create user-defined fields in a route entry database and are able to edit route entries while using the vapor analysis system in the field.

IPC Classes  ?

  • G01N 1/22 - Devices for withdrawing samples in the gaseous state
  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
  • G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
  • G01N 30/00 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography

36.

Gas analyzer system

      
Application Number 12112436
Grant Number 07835005
Status In Force
Filing Date 2008-04-30
First Publication Date 2009-08-27
Grant Date 2010-11-16
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Appel, Dirk
  • Marzoratti, Gaston E.
  • Nabar, Shrikrishna H.
  • Mouradian, Robert F.

Abstract

A gas analyzer system includes an optical source, an optical filter assembly, a controller, and an analyzer. The optical source generates an optical signal. The optical filter assembly includes different optical filters in which to filter the optical signal. During operation, the controller selects sequential application of each of the different optical filters in a path of the optical signal to modulate the optical signal using different frequency bands of optical energy. The modulated optical signal passes through an unknown sample. Based on absorption of the optical signal by the sample gas at different frequencies, the optical analyzer detects which types of multiple different gases are present in the sample.

IPC Classes  ?

  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light

37.

Methods and apparatus for performance verification and stabilization of radiation detection devices

      
Application Number 11511078
Grant Number 07544927
Status In Force
Filing Date 2006-08-28
First Publication Date 2009-05-21
Grant Date 2009-06-09
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Iwatschenko-Borho, Michael

Abstract

The rare earth metal Lutetium in compound form is used in check sources of various shapes and sizes to calibrate and tune radiation detection devices. Radioactive Lutetium-176, a naturally occurring (non man-made) isotope forming part of the Lutetium compound, produces gamma energies of approximately 90, 200, and 300 kilo-electron Volts which are used in the calibration. Such gamma energies are close to the predominant spectral lines of special nuclear materials such as U-235 and Pu-239, which is to be monitored by radiation detection devices. Lutetium in a radioactive calibration source (which is either integrated into the radiation detection device or positioned close to it during calibration) provides benefits including that no reactor or accelerator is required during production or use, for the creation of man-made radioactivity, no dangerous radiation exposure occurs and (because of the long half-life of Lu-176) the radioactive calibration source essentially never needs to be replaced. Moreover, the handling of such a source is much less restrictive and costly than that of a conventional man-made radioactive isotope.

IPC Classes  ?

  • G12B 13/00 - Calibrating of instruments or apparatus

38.

Reed relay for magnetic field measurement

      
Application Number 11849076
Grant Number 07710112
Status In Force
Filing Date 2007-08-31
First Publication Date 2009-03-05
Grant Date 2010-05-04
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Baturin, Nikolay
  • Esin, Alexander J.
  • Kulik, Alex
  • Masterov, Michael

Abstract

An apparatus for measuring a strength of a magnetic field, including a switch including contacts configured to change position when a switching threshold is reached, wherein the switching threshold is reached by modifying an external magnetic field around the switch, and a coil wound around the switch, wherein the coil is used to modify the external magnetic field, wherein a first current is driven through the coil wound around the switch until a first switching threshold is obtained, wherein a second current is driven through the coil wound around the switch until a second switching threshold is obtained, and wherein a value of the first current when the first switching threshold is reached and a value of the second current when the second switching threshold is reached are used to determine the strength of the magnetic field.

IPC Classes  ?

  • G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux

39.

Radiation measurement using multiple parameters

      
Application Number 11820488
Grant Number 07737401
Status In Force
Filing Date 2007-06-19
First Publication Date 2008-12-25
Grant Date 2010-06-15
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Iwatschenko-Borho, Michael
  • Trost, Norbert
  • Pijahn, Ralf

Abstract

An improved radiation detection device measures a broad range of dose rate levels. According to one arrangement, the radiation detection device calculates a radiation value based on, gamma count information representing counts for different energy levels of radiation in a radiation field as well as a radiation intensity indicator value (e.g., photomultiplier tube anode DC current, measured directly by conventional Analog to Digital Converters or indirectly by power or current consumption information indicating how much energy is required to maintain a photomultiplier tube at a constant voltage) that is at least proportional to an amount of overall radiation energy detected in the radiation sample. Based on a combination of the gamma count information and the radiation intensity indicator value, a controller associated with a corresponding radiation detection device can calculate a radiation dose rate associated with the received radiation sample.

IPC Classes  ?

40.

Self-diagnostic sensor system

      
Application Number 12127534
Grant Number 08603307
Status In Force
Filing Date 2008-05-27
First Publication Date 2008-11-27
Grant Date 2013-12-10
Owner Thermo Fisher Scientific, Inc. (USA)
Inventor
  • West, Steven J.
  • Gillette, Timothy C.

Abstract

A system for monitoring the viability of an electrochemical cell measures the impedance of the cell over a wide range of impedances and with diminished phase shift over prior methods so that a more nearly accurate assessment of the impedance can be made. The system is particularly useful for four electrode systems, but is not so limited. It may advantageously be incorporated in the cell itself to further minimize cabling artifacts.

IPC Classes  ?

41.

X-ray photoelectron spectroscopy analysis system for surface analysis and method therefor

      
Application Number 11866489
Grant Number 07875857
Status In Force
Filing Date 2007-10-03
First Publication Date 2008-06-19
Grant Date 2011-01-25
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Barnard, Bryan Robert

Abstract

An X-ray photoelectron spectroscopy analysis system for analysing an insulating sample 20, and a method of XPS analysis. The system comprises an X-ray generating means 30 having an exit opening 32 and being arranged to generate primary X-rays 46,56 which pass out of the exit opening in a sample direction towards a sample surface 22 for irradiation thereof. It has been found that the X-ray generating means in use additionally generates unwanted electrons 258 which may pass out of the exit opening substantially in the sample direction and cause undesirable sample charging effects. The system further comprises an electron deflection field generating means 380,480,580 arranged to generate a deflection field upstream of the sample surface. The deflection field is configured to deflect the unwanted electrons away from the sample direction, such that the unwanted electrons are prevented from reaching the sample surface.

IPC Classes  ?

  • H01J 47/00 - Tubes for determining the presence, intensity, density or energy of radiation or particles
  • H01J 49/00 - Particle spectrometers or separator tubes
  • G21K 1/06 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diffraction, refraction, or reflection, e.g. monochromators

42.

Centrifuge rotor assembly and method of connection thereof

      
Application Number 11637920
Grant Number 07837607
Status In Force
Filing Date 2006-12-13
First Publication Date 2008-06-19
Grant Date 2010-11-23
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Woodman, James R.

Abstract

A rotor assembly includes an actuator moveable between a first position and a second position. The rotator assembly also includes an engagement mechanism connected and moveable relative to the actuator, wherein the engagement mechanism engages a portion of a centrifuge when the actuator is in the first position and disengages from the portion of the centrifuge when the actuator is in the second position. Also, a method of connecting a rotor assembly to a centrifuge.

IPC Classes  ?

  • B04B 7/06 - Safety devices
  • B04B 5/02 - Centrifuges consisting of a plurality of separate bowls rotating round an axis situated between the bowls

43.

Shipping container

      
Application Number 11800960
Grant Number 07845894
Status In Force
Filing Date 2007-05-08
First Publication Date 2008-01-03
Grant Date 2010-12-07
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Dickinson, Randall Douglas
  • Horan, Patrick Joseph

Abstract

A shipping container for a product mounted on casters, weighing on the order of about 150 to 300 pounds and including a box shaped housing. The shipping container comprises a base. A pair of elongated, parallel disposed and spaced apart support members are fixedly mounted on the top of the base. Each support member includes a block of foam material fixedly mounted onto the base and having a tapered front end and a rear end. A strip of low friction material is fixedly mounted on top of the block of foam material.

IPC Classes  ?

  • B65G 7/00 - Devices for assisting manual moving or tilting heavy loads

44.

Functional and hyperfunctional siRNA

      
Application Number 11095383
Grant Number 07834170
Status In Force
Filing Date 2005-03-30
First Publication Date 2007-09-06
Grant Date 2010-11-16
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Khvorova, Anastasia
  • Reynolds, Angela
  • Leake, Devin
  • Marshall, William
  • Scaringe, Stephen

Abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes.

IPC Classes  ?

  • C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

45.

Tank for a system that outputs liquid at a user-defined constant temperature

      
Application Number 11330040
Grant Number 08092676
Status In Force
Filing Date 2006-01-11
First Publication Date 2007-07-12
Grant Date 2012-01-10
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Dickinson, Randall Douglas
  • Horan, Patrick Joseph
  • Lang, Nathan Norman

Abstract

A tank for use in a system that outputs a liquid at a user defined constant temperature in order to regulate the temperature of a piece of equipment includes a body of material defining a chamber for receiving and storing the liquid. The top wall has a fill port and one of the other walls includes an outlet port. An auxiliary port and fluid return port are also included. The body further includes a well, sized to accommodate a deionizer cartridge, extending down into the chamber from an opening in top wall that can be removed. A flow velocity reducer is disposed in the auxiliary port for reducing the velocity of the liquid entering the auxiliary port from the return fluid port and then passing into the fill port so that the liquid does not spray or splash onto the walls of the fill port.

IPC Classes  ?

  • B01D 35/18 - Heating or cooling the filters
  • C02F 1/02 - Treatment of water, waste water, or sewage by heating
  • F28F 13/12 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media by creating turbulence, e.g. by stirring, by increasing the force of circulation
  • F28F 19/00 - Preventing the formation of deposits or corrosion, e.g. by using filters

46.

Tank for a system that outputs liquid at a user-defined constant temperature

      
Application Number 11330037
Grant Number 07828048
Status In Force
Filing Date 2006-01-11
First Publication Date 2007-07-12
Grant Date 2010-11-09
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Dickinson, Randall Douglas
  • Horan, Patrick Joseph
  • Lang, Nathan Norman

Abstract

A tank for use in a system that outputs a liquid at a user defined constant temperature in order to regulate the temperature of a piece of equipment includes a body of material having a plurality of walls which collectively define a chamber for receiving and storing the liquid. The top wall has a manual fill port and one of the other walls includes an outlet port. An auxiliary port is located on the manual fill port and a return fluid port is located on the auto refill port. The body further includes a well which extends down into the chamber from an opening in top wall of the tank and which can be removed. The well is sized to accommodate a deionizer cartridge. When the well is removed, either a heater or an immersion pump can be disposed within the chamber. The tank also features a bag filter, a sight gauge and a flow velocity reducer. Finally, a cover assembly is removably mounted on the manual fill port and includes a funnel shaped cover and a removably sealing plug.

IPC Classes  ?

  • F28F 13/12 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media by creating turbulence, e.g. by stirring, by increasing the force of circulation
  • F28F 19/00 - Preventing the formation of deposits or corrosion, e.g. by using filters
  • B01D 35/18 - Heating or cooling the filters
  • C02F 1/02 - Treatment of water, waste water, or sewage by heating

47.

Spectrometer for surface analysis and method therefor

      
Application Number 11588689
Grant Number 07714285
Status In Force
Filing Date 2006-10-27
First Publication Date 2007-05-24
Grant Date 2010-05-11
Owner Thermo Fisher Scientific Inc. (USA)
Inventor Barnard, Bryan Robert

Abstract

A spectrometer (10) for sample surface analysis by irradiation of the surface by primary particles and a corresponding method of surface analysis spectroscopy. The spectrometer (10) provides sample viewing and secondary charged particle collection substantially normal to the sample surface. A collection chamber (22) comprises a secondary charged particle lens arrangement (20) to focus the emitted particles in a downstream direction along a first normal axis (24) and thereby to define a charged particle optical crossover location (25); and a light-reflecting optical element (50) downstream of the lens arrangement and arranged to receive image light (41) and reflect it away from a second normal axis (42) for providing a viewable image of the surface. The optical element (50) is positioned at, or near to, the crossover location (25) and comprises an opening (52) therethrough, such that the focused particles pass through the opening for downstream spectroscopic analysis substantially without obstruction by the optical element.

IPC Classes  ?

  • G01N 23/00 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or

48.

Method and apparatus for monitoring mercury in a gas sample

      
Application Number 11120182
Grant Number 07454952
Status In Force
Filing Date 2005-05-02
First Publication Date 2006-11-02
Grant Date 2008-11-25
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Kita, Dieter
  • Grassi, James H.
  • Socha, Jeffrey
  • Appel, Dirk

Abstract

Disclosed are a system and method for monitoring total mercury within a gas sample in a substantially continuous manner and for calibrating for both elemental and oxidized mercury. A converter of the Continuous Emission Monitoring System (CEMS) receives a gas sample containing vaporized mercury from a probe. The converter converts oxidized mercury present within the gas sample into an elemental mercury component and an oxidizing component using thermal cracking. The converter also reduces the pressure of the gas sample to minimize recombination of the elemental mercury component with the oxidizing components. A mercury analyzer of the system receives the reduced pressure gas sample from the converter and detects the fluorescence of the elemental mercury within the sample. The mercury analyzer holds the gas sample at the reduced pressure to reduce an effect of fluorescence quenching on the fluorescence of the elemental mercury within the sample and provides substantially accurate measurement of the concentration of the elemental mercury in the gas sample.

IPC Classes  ?

  • G01N 7/00 - Analysing materials by measuring the pressure or volume of a gas or vapour

49.

Device and method for diluting a sample

      
Application Number 10524382
Grant Number 07998434
Status In Force
Filing Date 2003-08-14
First Publication Date 2006-06-15
Grant Date 2011-08-16
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Shaw, Philip Neil
  • Marriott, Philip

Abstract

The present invention provides a pump device 50 which is usable to dilute a sample 52 before analysis. A first pump 54 pumps the sample to a mixing region 58 where it mixes with a diluent 66. A second pump 64 pumps the diluted sample to the analysis instrument. The flow of the diluent to the mixer is equal to the difference of the flow of the sample to the mixer and the flow of the diluted sample to the instrument. Pumps 54 and 64 are independently controllable by a controller unit which is arranged so that data from the instrument can be used to determine the dilution factor of the sample. Thus, the controller can control this dilution factor in real time, upon receipt of such data from the instrument, by change either one of (or both) the pump's flow rate.

IPC Classes  ?

  • F04B 53/00 - Component parts, details or accessories not provided for in, or of interest apart from, groups or

50.

Functional and hyperfunctional siRNA

      
Application Number 11101244
Grant Number 07691997
Status In Force
Filing Date 2005-04-07
First Publication Date 2005-11-03
Grant Date 2010-04-06
Owner THERMO FISHER SCIENTIFIC INC. (USA)
Inventor
  • Khvorova, Anastasia
  • Reynolds, Angela
  • Leake, Devin
  • Marshall, William
  • Scaringe, Stephen
  • Read, Steven

Abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes.

IPC Classes  ?

  • C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
  • A01N 43/04 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom
  • A61K 31/70 - CarbohydratesSugarsDerivatives thereof

51.

Method and apparatus for detecting high-energy radiation using a pulse mode ion chamber

      
Application Number 10815157
Grant Number 08223913
Status In Force
Filing Date 2004-03-31
First Publication Date 2005-10-06
Grant Date 2012-07-17
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Masterov, Michael
  • Esin, Alexander Joseph

Abstract

A method for measuring high-energy radiation includes applying a voltage pulse to electrodes in an ion chamber filled with a gas capable of forming charged ions by the high-energy radiation; measuring an ion current signal related to ion currents induced by the voltage pulse; and determining a magnitude of the high-energy radiation based on the ion current signal.

IPC Classes  ?

  • G01T 3/00 - Measuring neutron radiation
  • G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters
  • G21C 17/00 - MonitoringTesting
  • H01J 47/00 - Tubes for determining the presence, intensity, density or energy of radiation or particles

52.

System and method for product tracking and product temperature profiling

      
Application Number 10026840
Grant Number 09460413
Status In Force
Filing Date 2001-12-27
First Publication Date 2003-04-10
Grant Date 2016-10-04
Owner Thermo Fisher Scientific Inc. (USA)
Inventor
  • Elwood, Bryan M.
  • Tipton, Walter Jeff
  • Butts, Charles G.
  • Steinhoff, Paul M.

Abstract

A storage unit for tracking events associated with an item is disclosed that includes a storage unit, a tracking device, and a processing and/or storage device. The tracking device monitors the presence of an item associated with the storage unit and the temperature of the item at discrete intervals of time. The processing and/or storage device is electrically connected to the tracking device and stores information generated from the tracking device. An automated access system may also be provided that grants access to the storage unit only to authorized users. An external network may also be provided which allows a user to monitor the storage unit including, access to the storage unit, and a temperature of the storage unit.

IPC Classes  ?

  • G06Q 10/00 - AdministrationManagement
  • G06Q 10/08 - Logistics, e.g. warehousing, loading or distributionInventory or stock management
  • A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
  • G01K 1/02 - Means for indicating or recording specially adapted for thermometers
  • G06Q 20/20 - Point-of-sale [POS] network systems
  • G07C 9/00 - Individual registration on entry or exit
  • A61J 1/10 - Bag-type containers