Abstract

A magnetoresistive sensor sensitive to an out-of-plane applied magnetic field includes a sensing layer; a reference layer with a fixed magnetization, the direction of the fixed magnetization being perpendicular to the plane of the reference layer; a non-magnetic spacer layer separating the sensing layer and the reference layer; the sensing layer having spontaneously a magnetization vortex configuration in the absence of an applied magnetic field, the vortex core diameter varying in the presence of an applied magnetic field perpendicular to the plane of the reference layer.

IPC Classes  ?

• G01R 33/09 - Magneto-resistive devices
• G01R 33/00 - Arrangements or instruments for measuring magnetic variables
• H01F 10/32 - Spin-exchange-coupled multilayers, e.g. nanostructured superlattices

Abstract

The hydromechanical device (102) for supplying each of two opposing active chambers (vr1ca1, vr1ca2) of a double-acting receiving cylinder (vr1) for servo-controlled operation of at least one first output rod (vr1ts1, vr1ts2) INCLUDES: a first double-acting generating cylinder (vg1) INCLUDING a first movement input rod (vg1te1) which is rigidly connected to a first piston (vg1p1) that delimits two first opposing passive chambers (vg1cp1, vg1cp2), each of which is selectively connected to at least one of THE two opposing active chambers of the receiving cylinder (vr1); and an assembly (110) for driving the first rod (vg1te1) of the first generating cylinder (vg1), INCLUDING a movement-transforming screw-nut assembly (112, 114), one movement output component (114) of which is rigidly connected to the first rod (vg1te1) of the first generating cylinder (vg1) and the other movement input component (112) of which is rotated by a drive motor (m1).

IPC Classes  ?

• F15B 13/04 - Fluid distribution or supply devices characterised by their adaptation to the control of servomotors for use with a single servomotor
• F15B 13/044 - Fluid distribution or supply devices characterised by their adaptation to the control of servomotors for use with a single servomotor operated by electrically-controlled means, e.g. solenoids, torque-motors
• F15B 15/14 - Fluid-actuated devices for displacing a member from one position to anotherGearing associated therewith characterised by the construction of the motor unit of the straight-cylinder type

Abstract

A system for controlling the use of screens by a user, comprising a set of software modules each embedded in an apparatus of a set of apparatuses of said user, comprising screens, and a server connected to said apparatuses by a telecommunication network, wherein: said apparatuses are initially restricted to a first set of functions, and include means of determining behavioral information of said user and transmitting same to said server, said server is adapted for granting an additional function according to said behavioral information, and for transmitting, to the software module of a selected apparatus, a message to enable said user to access said additional function.

IPC Classes  ?

• G06F 21/12 - Protecting executable software
• G06F 11/34 - Recording or statistical evaluation of computer activity, e.g. of down time, of input/output operation

Abstract

An NPF radiofrequency device includes a first end terminal E1, four first branches BR10, BR11, BR12, BR13 connected to E1 and each including a capacitor, respectively C0, C1, C2, C3, having the same capacitance, including a first terminal and a second terminal connected to ground, and a switch arranged between E1 and the first terminal of the capacitor of the first branch; the device being designed to, in each first branch BR1i, close the switch at each time pT0+(i)T0/4, for T0/4, where p is a natural number and T0 is the period of the clock signal; the device including at least two successive second branches from among an ordered set of second branches BR20, BR21, BR22, BR23, the second branch BR2i including a second end terminal E2i, and each second branch BR2k of the device including, for each first branch, BR11, i=0 to 3, a switch between the first terminal of the capacitor Ci and the second branch, the device being designed to close the switch at each pT0+(i+k)T0/4, for T0/4.

IPC Classes  ?

• H03K 17/56 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices
• H03H 7/06 - Frequency selective two-port networks including resistors

Abstract

A catalytic material comprising at least one group VIB metal at least partly in sulfide form, at least one group IVB metal at least partly in sulfide form, and an electrically conductive support wherein said group VIB metal is chosen from molybdenum and/or tungsten, said group IVB metal is chosen from titanium, zirconium and/or hafnium.

IPC Classes  ?

• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 1/27 - Ammonia
• C25B 3/07 - Oxygen containing compounds
• C25B 11/063 - Valve metal, e.g. titanium
• C25B 11/065 - Carbon
• C25B 11/067 - Inorganic compound e.g. ITO, silica or titania
• H01M 4/90 - Selection of catalytic material

Abstract

The invention relates to a method for producing an optoelectronic device with vertical nanostructures, comprising an active zone (ZA) designed to emit ultraviolet photons from radiative recombinations of electron-hole pairs, or designed to generate electron-hole pairs from absorbed ultraviolet photons; the vertical nanostructures being made of n-type doped gallium nitride GaN, and formed on selective epitaxy zones (SAG) by epitaxial growth; the method comprising a step of selective etching of the vertical nanostructures retaining a remaining portion (30) of each vertical nanostructure, suitable for maintaining a mechanical strength of lateral zones (41) of an electron transport layer made of a III-n alloy comprising aluminium Al.

IPC Classes  ?

• H10H 20/01 - Manufacture or treatment
• H10H 20/818 - Bodies characterised by the crystal structures or orientations, e.g. polycrystalline, amorphous or porous within the light-emitting regions
• H10H 20/821 - Bodies characterised by their shape, e.g. curved or truncated substrates of the light-emitting regions, e.g. non-planar junctions
• H10H 20/825 - Materials of the light-emitting regions comprising only Group III-V materials, e.g. GaP containing nitrogen, e.g. GaN

Abstract

The invention relates to a method for in vitro or ex vivo diagnosis of male infertility, resulting from a dysfunction of the lipid metabolism of spermatozoa, in an individual, as well as a kit and the use of one or more specific marker(s) for this diagnosis.

Abstract

A system for determining a degree of dependence on screens of a user, including at least one software module embedded in a set of information processing apparatuses, adapted for collecting first measurements about the behavior of the applications installed on said information processing apparatuses and second measurements about the behavior of said information processing apparatuses; a database for storing said measurements; a server for periodically determining an aggregation of said measurements and a degree of dependence on screens according to said aggregation.

IPC Classes  ?

• G06F 11/34 - Recording or statistical evaluation of computer activity, e.g. of down time, of input/output operation
• G06F 11/30 - Monitoring

Abstract

An electrode and the manufacturing method thereof, the electrode including a body at least partially covered with a composite coating including a polypyrrole polymer or derivatives thereof, the polymer including pyrrole monomeric units having a side chain including at least one carboxylate group. Particles of a metal oxide based on at least one metal, the amount of the at least one metal of the metal oxide being smaller than or equal to 7 mmol·cm−3 per carboxylate group of the pyrrole monomeric units. The electrode is improved in particular in terms of resources, environmental impact and cost, while preserving a satisfactory electrocatalytic activity.

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/04 - Processes of manufacture in general
• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/139 - Processes of manufacture

Abstract

In view of the problems and the like of the prior art, the purpose of the present invention is to provide a method for imaging body tissue rapidly and robustly using waveform inversion from ultrasound examination data.　The method for imaging body tissue rapidly and robustly using waveform inversion from ultrasound examination data according to the present invention comprises: (a) a step for acquiring ultrasound examination data; (b) a step for generating one wave field by means of a plurality of computers (CPUs); (c) a step for integrating squared errors (which constitute fc in expression (5)) from all CPUs, each squared error being the error between a waveform recorded at a reception point from the wave field and an observed waveform obtained in step (a); (d) a step for re-dividing a correction gradient and a pseudo Hessian matrix into regions with an equal number of CPUs in the x-direction; (e) a step for re-dividing from the uniform regions in the x-direction into regions with an equal number of CPUs in the y-direction; (f) a step for calculating a step length required for model updating in full-waveform inversion using a quasi-Newton method while maintaining the division of regions in the x-direction; and (g) a step for repeating the steps (b) to (f) to obtain imaging of a viscosity Q value in addition to a sound wave propagation velocity. Expression 5: Here, fc (scalar quantity) is a cost function representing the sum of squared residuals between the observed data (d_obs) and the synthetic data (d_syn) calculated from the initial model at all times of all reception points, and Ns, Nr, Nt are respectively the number of transmission points, the number of reception points, and the number of time samples.

IPC Classes  ?

• A61B 8/13 - Tomography

Abstract

222222O is oxidized to oxygen, and d) recovering the CO at the outlet of the cathode compartment (2), the deep eutectic solvent being chosen from a mixture of at least one ammonium salt and of at least one amine, a mixture of at least one ammonium salt and of at least one polyol, and a combination of these mixtures.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials
• C25B 1/23 - Carbon monoxide or syngas
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/065 - Carbon
• C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
• C25B 15/08 - Supplying or removing reactants or electrolytesRegeneration of electrolytes
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms

Abstract

A method for manufacturing a spin-orbit torque effect memory, referred to as SOT memory, which is simple to execute and which offers a memory with a switching efficiency at least equivalent to the SOT memories of prior art. For this, the manufacturing method includes depositing a conductive layer, referred to as a spacer, onto a magnetic stack; etching the magnetic stack using the spacer as an etching mask so as to form a magnetic tunnel junction; and forming an SOT track on the spacer.

IPC Classes  ?

• H10N 50/10 - Magnetoresistive devices
• H10N 50/01 - Manufacture or treatment
• H10N 50/20 - Spin-polarised current-controlled devices
• H10N 50/80 - Constructional details

Abstract

The invention relates to a photoelectrochemical converter (1) comprising a PIN-type photovoltaic cell (3) and an electrochemical module (2) attached to the photovoltaic cell, wherein the electrochemical module comprises anode (20) and cathode (21) blocks, and an electrolysis cell (22) sandwiched between the anode and cathode blocks, wherein the electrolysis cell is supplied with electrical power by the photovoltaic cell in order to oxidise water, wherein the photoelectrochemical converter comprises a water inlet opening (32) formed on the anode block in order to add water to the converter, wherein the electrolysis cell comprises a stack containing an anode (23), a proton exchange membrane (25) and a cathode (24), and wherein the anode block (20) is sandwiched between the electrolysis cell (25) and the photovoltaic cell (3) and comprises an anode fluid circulation system (30) that comprises an anode exchange opening (31) that opens onto the anode (23) and an anode channel (30) shaped to convey water from the water inlet opening to the anode.

IPC Classes  ?

• C25B 15/08 - Supplying or removing reactants or electrolytesRegeneration of electrolytes
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 3/07 - Oxygen containing compounds
• C25B 3/26 - Reduction of carbon dioxide
• C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
• C25B 9/65 - Means for supplying currentElectrode connectionsElectric inter-cell connections
• C25B 11/056 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material consisting of textile or non-woven fabric
• C25B 11/065 - Carbon
• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
• H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
• H10K 30/57 - Photovoltaic [PV] devices comprising multiple junctions, e.g. tandem PV cells
• C25B 11/054 - Electrodes comprising electrocatalysts supported on a carrier
• C25B 11/031 - Porous electrodes
• H10F 10/172 - Photovoltaic cells having only PIN junction potential barriers comprising multiple PIN junctions, e.g. tandem cells
• H10F 10/174 - Photovoltaic cells having only PIN junction potential barriers comprising monocrystalline or polycrystalline materials

Abstract

The present invention relates to a method for the in vitro or ex vivo diagnosis of the survival outcomes of a patient suffering from acute myeloid leukemia (AML), comprising a step of detecting the expression of at least newly identified AML biomarker genes.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

A palletisation method, wherein: articles (i) are transported towards a loading point, the articles (i) are loaded by a loading device onto a container arranged in the loading station, the loading device being controlled by a computer control device, the method further including generating a stable arrangement of the articles (i) on the container upstream of their loading, the stable arrangement includes placing articles having substantially similar heights to form layers, wherein a partial layer having a first height occupies part of the container and at least one complementary partial layer having a second height occupies a second unoccupied part such that the entire surface area of the container is occupied.

IPC Classes  ?

• B65G 61/00 - Use of pick-up or transfer devices or of manipulators for stacking or de-stacking articles not otherwise provided for

Abstract

A method for additive manufacturing of a first ferromagnetic object (9), characterized in that it comprises a step of varying at least one parameter of the manufacturing method in order to locally modify the magnetic permeability of the first object so as to integrate a magnetic signature into the first object.

IPC Classes  ?

• B23K 9/04 - Welding for other purposes than joining, e.g. built-up welding
• B33Y 10/00 - Processes of additive manufacturing

Abstract

The present invention relates to an X-ray imaging device (1) comprising an X-ray source (2) that generates an X-ray beam (F), a two-dimensional X-ray detector (3) comprising pixels (3a), a sample holder (4) configured to hold a sample (E), and at least one modulator (5), wherein the at least one modulator (5) is a membrane on which a spiral-shaped transmission modulation pattern is formed.

IPC Classes  ?

• A61B 6/42 - Arrangements for detecting radiation specially adapted for radiation diagnosis
• A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
• G21K 7/00 - Gamma ray or X-ray microscopes
• G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
• A61B 6/06 - Diaphragms
• A61B 6/40 - Arrangements for generating radiation specially adapted for radiation diagnosis
• G21K 1/10 - Scattering devicesAbsorbing devices

Abstract

A non-volatile field-effect transistor includes a gate electrode including a first contact, a source comprising a second contact, a drain including a third contact, a channel between the drain and the source and formed by a two-dimensional electron gas, a remanent-state subassembly having two electrically controllable remanent states comprising at least one oxide layer, and a reducing layer made of at least one metal-type reducing material having an atomic concentration of metal elements greater than 50%. The application of a voltage between the first contact and another contact results in a non-volatile modulation of the conductivity of the two-dimensional gas.

IPC Classes  ?

• H10D 30/47 - FETs having zero-dimensional [0D], one-dimensional [1D] or two-dimensional [2D] charge carrier gas channels having 2D charge carrier gas channels, e.g. nanoribbon FETs or high electron mobility transistors [HEMT]
• H10D 64/68 - Electrodes having a conductor capacitively coupled to a semiconductor by an insulator, e.g. MIS electrodes characterised by the insulator, e.g. by the gate insulator
• H10N 70/20 - Multistable switching devices, e.g. memristors

Abstract

The invention relates to a floating hydroelectric power plant, intended to be partially submerged in a watercourse, comprising a flotation member (10) comprising at least two shells (12) coupled by a frame (14) including a floor (15) extending in a main plane (B), and, for each shell (12), a connecting element (30 to 33) connecting the shell (12) to the floor (15); a channel (20) comprising two turbines (36) mounted counter-rotating along two axes of rotation (X, X'), respectively, together defining a secondary plane (C), and telescopic rails (50, 51), each telescopic rail being located entirely below the main plane (B) and connecting one of the connecting elements of the frame (14) to the channel (20), the telescopic rails being configured to allow the channel (20) to translate in a direction (Z) perpendicular to the main plane (B), so that an upper face (FS) of the channel (20) remains below the main plane (B).

IPC Classes  ?

• F03B 17/06 - Other machines or engines using liquid flow, e.g. of swinging-flap type
• F03B 13/26 - Adaptations of machines or engines for special useCombinations of machines or engines with driving or driven apparatusPower stations or aggregates characterised by using wave or tide energy using tide energy

Abstract

The invention relates to a high-frequency rheometer (1) comprising a first element (2) and a second element (3), the first element and the second element being movable relative to one another, the rheometer being intended to characterise the rheological properties of a material (4) inserted between the first element and the second element, the rheometer further comprising: - a first actuator (11) configured to generate a periodic high-frequency displacement of the first element and/or of the second element; - a second actuator (12) configured to generate a low-frequency displacement of the first element and/or of the second element, the low frequency being strictly lower than the high frequency; and - a first detection means (6) configured to measure a response of the material to the displacement between the first element and the second element.

IPC Classes  ?

• G01N 3/32 - Investigating strength properties of solid materials by application of mechanical stress by applying repeated or pulsating forces
• G01N 3/38 - Investigating strength properties of solid materials by application of mechanical stress by applying repeated or pulsating forces generated by electromagnetic means
• G01N 11/00 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties

Abstract

The present invention relates to a method for preparing an organic-inorganic hybrid solid electrolyte (HSE) based on an inorganic phase synthesized in-situ in the presence of polymer. The approach described delivers flexible membranes with high ionic conductivity values (>10-4S/cm at room temperature) and excellent mechanical properties, especially in terms of yield stress (σy), which are suitable for electrochemical applications in solid-state lithium metal batteries.

IPC Classes  ?

• H01M 10/0562 - Solid materials
• H01M 10/052 - Li-accumulators
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes

Abstract

The invention relates to a collimation device (5) for an X-ray detection system (1), the collimation device comprising a substantially planar support (51) made of a material with partial or zero radiotransparency, the support being intended to be rotated about an axis of rotation (52) perpendicular to the plane in which the support lies, the support being provided with a slit (54) that is fully transparent to X-rays and extends through the thickness of the support in order to create an X-ray flux when the support is exposed to an X-ray source, wherein the shape of the slit, when projected onto the plane of the support, is a curve.

IPC Classes  ?

• G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
• G01T 1/164 - Scintigraphy

Abstract

The invention concerns a method for fabricating an array of magnets (10), the method comprising: - a step of deposition of a coercivity changing element according to a pattern on a first material having a first coercivity value, the coercivity changing element being adapted to change the coercivity of the first material, and - a step of diffusion of the coercivity changing element into certain regions to form a magnetic layer (16) having first areas (A1) made of the first material and second areas (A2) having a second coercivity, made of a second material comprising the first material and the coercivity changing element.

IPC Classes  ?

• H01F 7/02 - Permanent magnets
• H01F 1/032 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials
• H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
• H01F 13/00 - Apparatus or processes for magnetising or demagnetising
• H01F 1/00 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties
• H01F 41/18 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for applying magnetic films to substrates by cathode sputtering
• H01F 10/12 - Thin magnetic films, e.g. of one-domain structure characterised by magnetic layers characterised by the composition being metals or alloys

Abstract

The invention relates to an electrochlorination electrode (1) and to the related manufacturing method, the electrode comprising an electrically conductive substrate (10), at least one catalytic layer (11) comprising metal and metalloid chemical elements, characterised in that the at least one catalytic layer (11) comprises ruthenium with a mass proportion of between 10% and 40%, titanium with a mass proportion of between 40% and 79%, and boron with a mass proportion of between 1% and 20%, the mass proportions being given relative to the total mass of the metal and metalloid elements in the at least one catalytic layer (11).

IPC Classes  ?

• C02F 1/461 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
• C02F 1/467 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis by electrochemical disinfection
• C25B 1/26 - ChlorineCompounds thereof
• C25B 11/053 - Electrodes comprising one or more electrocatalytic coatings on a substrate characterised by multilayer electrocatalytic coatings
• C25B 11/093 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds at least one noble metal or noble metal oxide and at least one non-noble metal oxide

Abstract

The invention relates to a method for obtaining a layer at least partially made of a nitride (N), first comprising the provision of a stack comprising at least one assembly of pads (1000A1-1000B4) extending from a substrate (100). Each pad comprises at least one creep section (220A1-220A5) and one crystalline section (300A1,300A5) surmounting the creep section (200A1-200A5). Then, a crystallite (510A1-510A5) is epitaxially grown on at least some of said pads until coalescence of the crystallites, so as to form a nitride layer (550A). The pads of the assembly are distributed over the substrate, such that the relative arrangement of the pads of the assembly is such that during the epitaxy of the crystallites, the progressive coalescence of the crystallites is always done between, on the one hand, a crystallite or a plurality of coalesced crystallites and, on the other hand, an isolated crystallite.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• C30B 25/18 - Epitaxial-layer growth characterised by the substrate
• C30B 29/40 - AIIIBV compounds

Abstract

In the present invention, thanks to a prospective multicenter cohort study including 200 pregnant patients with five-serum sampling per patient, inventors investigated the concentrations of protein biomarkers in the plasma of high risk pregnant women during the second and third trimesters to predict spontaneous preterm birth. Inventors demonstrated that PROK1 (Prokineticin 1) also called EG-VEGF (Endocrine Gland-derived Vascular Endothelial Growth Factor), is secreted by the placenta and exhibits increased serum levels in patients with sPTB, before 37 weeks of gestation, compared with uncomplicated pregnant women. More precisely, Women with spontaneous preterm birth exhibited higher concentrations of serum PROK1/EG-VEGF than uncomplicated patients at 20 weeks, 24 weeks, 28 weeks and 32 weeks. Accordingly, serum PROK1/EG-VEGF concentrations could be considered as biomarker of spontaneous preterm birth in high-risk pregnant women.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

A method for detecting biological objects by means of an SPR imaging detection system comprising an optical measurement device configured to generate plasmon resonance on a functionalized surface when said surface is exposed to a gas; the method comprising: an assimilation step by exposing the functionalized surface to a sample of interest formed of an aqueous carrier liquid containing the biological objects; a step of removing the liquid in contact with the functionalized surface and exposing the surface to a gas not containing the biological objects, said objects remaining bound to the ligands of the sensitive site of the functionalized surface; a step of acquiring an image of the sensitive site; a step of detecting the biological objects from the acquired image.

IPC Classes  ?

• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• G01N 21/552 - Attenuated total reflection

Abstract

A new peptide and its use as a vector for the transport of molecules after conjugation through cellular barriers for the diagnosis, prognosis or treatment of pathologies of the central nervous system (CNS).

IPC Classes  ?

• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans

Abstract

The application relates to a method for protecting a microgrid from a voltage drop or sag occurring in a main grid connected to said microgrid, the method comprising the following steps: a. supplying (105) power to the microgrid through the main grid; b. ascertaining that the voltage drop or sag is occurring in the main grid by executing the following steps: i. measuring (110) an instantaneous output voltage; ii. comparing (130) the measured instantaneous output voltage with a reference instantaneous output voltage; iii. Incrementing (140) a counter when the measured instantaneous output voltage differs from the reference instantaneous output voltage by more than a voltage threshold; and iv. ascertaining (150) that the voltage drop or sag is occurring in the main grid when the counter holds a value that exceeds a counter threshold; and c. disconnecting the microgrid from the main grid when the voltage drop or sag occurring in the main grid has been ascertained.

IPC Classes  ?

• H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks

Abstract

The application relates to a method for controlling a microgrid (10) comprising the steps of: maintaining a switching device (60) connecting two busbars (30, 40) of the microgrid (10) and a circuit breaker (20) connecting the microgrid (10) to a utility grid (100) closed, the microgrid (10) being operated in a grid connected mode; measuring (202) a voltage present in the microgrid (10); determining (205) if the measured voltage corresponds to a loss of voltage or a fault in the microgrid (10); and if a the loss of voltage or fault is detected in the microgrid (10), opening (210) the switching device (60), the critical loads being supplied by the battery energy storage system (50) and the circuit breaker (20) remaining closed during (215) at least a fault ride through period.

IPC Classes  ?

• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers

Abstract

in vitroinvivovivo, as it meets the performance requirements generally expected in this field, such as sensitivity and chemical stability, particularly over the long term.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 27/414 - Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
• H01L 29/16 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only elements of Group IV of the Periodic System in uncombined form
• H01L 29/808 - Field-effect transistors with field effect produced by a PN or other rectifying junction gate with a PN junction gate

Abstract

The present invention concerns a pharmaceutical composition for use in the prevention or treatment of cerebral cavernous malformations (CCM) comprising a transient receptor potential vanilloid 4 (TRPV4) inhibitor.

IPC Classes  ?

• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• A61K 31/18 - Sulfonamides
• A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
• A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
• A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
• A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

Acoustic scanning microscopy technique, in which the probe is formed by at least one acoustically resonant gas bubble immersed in a liquid medium (16) and excited by an acoustic wave that propagates in the liquid medium (16). The resonant response of the bubble is measured with a transducer (8).

IPC Classes  ?

• G01N 29/06 - Visualisation of the interior, e.g. acoustic microscopy
• G01N 29/12 - Analysing solids by measuring frequency or resonance of acoustic waves
• G01N 29/24 - Probes

Abstract

The present invention relates to new glycomimetic molecules which selectively bind to the L-SIGN receptor, finding application in the medical field and, in particular, in the prevention and treatment of viral infections, in the immunotherapy of liver tumors and in the treatment of immune diseases.

IPC Classes  ?

• C07H 19/056 - Triazole or tetrazole radicals
• A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
• A61K 31/7064 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines

Abstract

The invention relates to a method for determining at least one component of the positioning of a receiver (24) relative to a transmitter (22), the transmitter (22) comprising at least two magnetic generators (30, 32, 34), the method comprising the following steps: - measuring a resulting magnetic field; - demodulating the measurement signal so as to determine a plurality of candidate measurements; - applying, to each candidate measurement, a correction that aims to compensate for a directional orthogonality defect in the magnetic generators (30, 32, 34) so as to obtain a corresponding corrected measurement; - calculating a value representative of the likelihood that this candidate measurement reflects the actual contributions of each alternating magnetic field; - selecting a selected measurement corresponding to the highest likelihood; and - determining the at least one component of the positioning of the receiver (24).

IPC Classes  ?

• G01S 1/04 - Beacons or beacon systems transmitting signals having a characteristic or characteristics capable of being detected by non-directional receivers and defining directions, positions, or position lines fixed relatively to the beacon transmittersReceivers co-operating therewith using radio waves Details
• G01R 33/00 - Arrangements or instruments for measuring magnetic variables
• G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux
• G01R 33/36 - Electrical details, e.g. matching or coupling of the coil to the receiver
• G01S 5/02 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using radio waves

Abstract

The present disclosure relates to phase-change-based material switch formed on a support substrate, and including: a region made of said phase-change material coupling first and second conduction electrodes of the switch; and a waveguide interposed between the support substrate and the region made of said phase-change material, and including a center region made of a first material having a first optical index surrounded by a peripheral region made of a second material having a second optical index less than the first optical index.

IPC Classes  ?

• H01H 37/32 - Thermally-sensitive members
• G02B 6/42 - Coupling light guides with opto-electronic elements
• H01H 11/00 - Apparatus or processes specially adapted for the manufacture of electric switches
• H10N 70/00 - Solid-state devices having no potential barriers, and specially adapted for rectifying, amplifying, oscillating or switching
• H10N 70/20 - Multistable switching devices, e.g. memristors

Goods & Services

Electronic components; Data storage devices and media; Semi-conductors; All the aforesaid goods relating to the field of spintronics. Printed matter and Educational materials; Printed publications; Educational publications; Books; Journals; All the aforesaid goods being in the field of spintronics. Education and training In the field of spintronics; Arranging and conducting of seminars and conferences In the field of spintronics. Engineering services; Technical and scientific research services; Design services; Research and development services; Technological and scientific consultancy; Design and testing for new product development; All the aforesaid services being provided in the field of spintronics.

Abstract

A method for purifying a protein of interest includes the preparation of a fusion protein in which this protein of interest is fused to a protein tag having the protein Mmi1 of a microorganism of the genus Schizosaccharomyces or a fragment thereof, the bringing into contact of this fusion protein with a ribonucleic acid molecule containing at least one motif of UNAAAC nucleotide sequence, so as to allow the affinity binding of the protein tag with this ribonucleic acid molecule, and the recovery of the protein of interest.

IPC Classes  ?

• C07K 1/22 - Affinity chromatography or related techniques based upon selective absorption processes
• C07K 14/39 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi from yeasts

Abstract

The present invention relates to a composite material comprising at least one textile commodity polymer and protein fibers comprising at least one amyloid structure. The invention also relates to a method for preparing such a material, as well as to the use of such a material for adsorbing a pollutant or extracting metal ions.

IPC Classes  ?

• B01J 20/26 - Synthetic macromolecular compounds
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• D01F 2/00 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof
• D01F 4/04 - Monocomponent artificial filaments or the like of proteinsManufacture thereof from casein
• D01F 6/46 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyolefins
• D01F 6/88 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
• C08L 77/00 - Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chainCompositions of derivatives of such polymers
• C08L 1/02 - CelluloseModified cellulose
• C08L 23/04 - Homopolymers or copolymers of ethene
• C08L 23/10 - Homopolymers or copolymers of propene
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
• C08L 89/00 - Compositions of proteinsCompositions of derivatives thereof
• C08L 25/04 - Homopolymers or copolymers of styrene
• C08L 27/06 - Homopolymers or copolymers of vinyl chloride
• C08L 23/08 - Copolymers of ethene
• D01F 6/44 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds
• C02F 101/30 - Organic compounds
• C08L 25/06 - Polystyrene
• B01D 39/04 - Organic material, e.g. cellulose, cotton
• B01D 39/08 - Filter cloth, i.e. woven, knitted or interlaced material
• B01D 39/16 - Other self-supporting filtering material of organic material, e.g. synthetic fibres
• D01F 4/00 - Monocomponent artificial filaments or the like of proteinsManufacture thereof

Abstract

The invention relates to a device (1, 1A, 1B, 1C, 1D) for creating an evanescent field (3) at the surface of a dioptre (4) separating two media that have different refractive indices, the device comprising: - a light source (6A, 6B, 6C, 6D); - a lens (9A, 9B, 9C, 9D) comprising an object focal plane positioned at the surface of the dioptre, and a pupil plane (PP) comprising a subcritical region (R2) and a supercritical region (R1); - an active optical means (7A, 7B, 70, 7D) comprising an active surface (10A, 10B, 10C, 10D) extending at least through the entirety of the supercritical region (R1') of a conjugate plane of the pupil plane or extending through a conjugate plane of the object focal plane of the lens, the active optical means comprising a set of individually controllable microelements configured to illuminate the entire supercritical region of the lens.

IPC Classes  ?

• G02B 21/08 - Condensers
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G02B 27/56 - Optics using evanescent waves, i.e. inhomogeneous waves
• G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/33 - Immersion oils
• G02B 21/34 - Microscope slides, e.g. mounting specimens on microscope slides

Abstract

A method for a synthesis of a metal catalyst, including providing at least one metal complex including a metal ion and a non-chelating complexing agent having carbon, the complex having a decomposition temperature, and performing a pyrolysis of the complex at a temperature greater than or equal to a decomposition temperature of the complex, whereby inducing a formation of nanoparticles surrounded by a carbon matrix to form the catalyst. Thanks to the carbon matrix, the catalysts provided herein can be corrosion resistant, self-healing, more cost-effective, and can have higher catalytic activity. The synthesis of the catalyst and its properties can furthermore be improved compared to catalysts formed from a complex including a chelating.

IPC Classes  ?

• H01M 4/92 - Metals of platinum group
• C25B 11/031 - Porous electrodes
• C25B 11/055 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material
• C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
• H01M 4/88 - Processes of manufacture

Abstract

The invention relates to a method for reconstructing an object by x-ray tomography by means of x-ray sources and detectors. The method comprises the following steps: obtaining (EO) positions of the x-ray sources and detectors; pre-calculating (E1) a set of directions; calculating (E2) a tomographic incompleteness vector map; calculating (E3) a tomographic incompleteness map of the metrics IM(x); calculating (E4) regularization terms from the tomographic incompleteness vector map and from the tomographic incompleteness map of the metrics; and solving (E5), iteratively, a regularized tomographic reconstruction problem by means of the calculated regularization terms.

IPC Classes  ?

• G06T 11/00 - 2D [Two Dimensional] image generation

Abstract

The invention relates to a connecting device (30) suitable for connecting at least one first element (17) and one second element to one another, and for moving the or each first element relative to the second element. The connecting device comprises a fixed portion (31), a movable portion (32) which is kinematically linked and connected to the or each first element, and a joint (33) which connects the fixed portion and the movable portion at least pivotably about an axis of rotation (A30). The joint comprises, for the axis of rotation, at least one strand (37) that is elastically deformable and extends in a manner that is both substantially parallel and offset relative to the axis of rotation, and that connects at least one fixed support (318) of the fixed portion to at least one movable support (36) of the movable portion.

IPC Classes  ?

• H01H 1/22 - Contacts characterised by the manner in which co-operating contacts engage by abutting with rigid pivoted member carrying the moving contact
• H01H 71/08 - TerminalsConnections

Abstract

An electrode comprising a self-supporting porous structure of expanded graphite and an electrical connector. Method for manufacturing a self-supporting porous structure of expanded graphite, said method comprising the following steps: preparing a suspension of expanded graphite particles in a liquid; sonicating said suspension of graphite particles by applying ultrasound, to obtain a homogenized suspension; and filtering said homogenized suspension under pressure to obtain an expanded porous structure which is at least partially and preferably substantially dry.

IPC Classes  ?

• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 4/88 - Processes of manufacture
• H01M 4/90 - Selection of catalytic material
• H01M 4/96 - Carbon-based electrodes
• H01M 8/16 - Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts

Abstract

A prognostic risk score for chemosensitive cancer, in particular acute myeloid leukemia (AML), based on somatic genetic abnormalities affecting certain genes of the mitochondrial genome.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

A method for determining spatial coordinates of a source causing a dispersion effect in a domain, the dispersion effect being approximated by a system of partial differential equations, the method including computer-implemented steps, of obtaining measurements each quantifying at a point in space in the domain and at a given time a state variable modeled by the system of partial differential equations at the point and at the time, and of iteratively minimizing differences between the measurements and the computations of the system of equations to locate a position of the source. The system of equations is expressed in terms of finite differences generated by radial basis functions, the system of equations being solved in a least-squares context, using a least-squares solver, the system of equations having been subject to adjoint quadratic solution with radial basis functions chosen from polyharmonic-spline functions, inverse-multiquadric functions, or Gaussian functions.

IPC Classes  ?

• G06F 17/13 - Differential equations

Abstract

A device for transdermal electrochemical measurements, comprising a polymeric support having a surface provided for contact with skin, an array of polymeric microneedles integral with the support and projecting outward from the surface of the support, and a porous and/or nano/micro-structured bioelectrode. A biologically active species is immobilized on the surface of a conductive material. The microneedles and a surface of contact of the support with the skin are formed of a biocompatible crosslinked hydrogel, non-electron-conductive in the dry state and electrolyte-conductive upon contact with an aqueous fluid. The bioelectrode is arranged in contact with the hydrogel and is free of direct contact with the skin. Methods for preparing and using the device are also described.

IPC Classes  ?

• A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
• A61L 31/04 - Macromolecular materials
• A61L 31/14 - Materials characterised by their function or physical properties

Abstract

A device having a polymeric support with a surface for contact with skin, an array of solid polymeric microneedles integral with the support and projecting outward from the surface of the support provided for contact with the skin, and an electrode. The microneedles and the surface of contact of the support with the skin are formed of a crosslinked hydrogel, non-electron-conductive in the dry state and electrolyte-conductive upon contact with an aqueous fluid. The electrode is arranged in contact with the hydrogel provided to swell upon contact with an aqueous fluid and is free of direct contact with the skin. A method for preparing the device and uses thereof are also described.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
• A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
• A61L 31/04 - Macromolecular materials
• A61L 31/14 - Materials characterised by their function or physical properties

Abstract

An in vitro or ex vivo method for producing and isolating a cell subpopulation including T cells specific for an antigen linked to a disease of interest, which includes steps of obtaining, from an isolated human biological sample, a population of mononuclear cells including T cells specific for the antigen with a high proliferative capacity, culturing these mononuclear cells in a suitable cell culture medium containing the antigen, and isolating T cells specific to the antigen which do not express the CD45RO and CD27 markers at their surface. The cell subpopulation thus obtained and isolated finds application in particular for the treatment of the disease of interest.

IPC Classes  ?

• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
• B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells

Abstract

The present invention relates to compounds of formula (I). It also relates to a process for preparing a compound as well as to the use of these compounds as a medicament, in particular in the treatment of cancer.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• A61K 31/28 - Compounds containing heavy metals
• A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
• A61K 31/44 - Non-condensed pyridinesHydrogenated derivatives thereof
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 35/00 - Antineoplastic agents
• C01G 55/00 - Compounds of ruthenium, rhodium, palladium, osmium, iridium, or platinum
• C07D 235/18 - BenzimidazolesHydrogenated benzimidazoles with aryl radicals directly attached in position 2
• C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table

Abstract

A classification device, including a pre-processing stage, a material system and an identification stage. The pre-processing stage transforms a signal of interest into an excitation signal; the material system includes a magnetic medium subdivided into a plurality of zones either in a first magnetic state or in a second magnetic state, an excitation module generating, from the excitation signal, a physical excitation quantity adapted to displace the magnetic domain walls in the magnetic medium, and a reading module measuring the final magnetic configuration reached by the magnetic medium; and the identification stage determines a class to which the signal of interest belongs from the final magnetic configuration.

IPC Classes  ?

• G16C 60/00 - Computational materials science, i.e. ICT specially adapted for investigating the physical or chemical properties of materials or phenomena associated with their design, synthesis, processing, characterisation or utilisation
• G16C 20/70 - Machine learning, data mining or chemometrics

Abstract

An electrode comprising an electronically conductive material at least in part forming a reservoir, the material being permeable and porous; an enzyme compound disposed in the reservoir; and optionally a current collector.

IPC Classes  ?

• H01M 4/90 - Selection of catalytic material
• C12N 11/14 - Enzymes or microbial cells immobilised on or in an inorganic carrier
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 8/16 - Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts

Abstract

The present invention relates to novel trityl-nitroxide radicals as polarizing agents for Dynamic Nuclear Polarization (DNP).

IPC Classes  ?

• C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
• C07D 207/46 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
• G01N 24/12 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using double resonance

Abstract

The present invention relates to a method of synthesis of colloidal InSb quantum dots (InSb QDs) comprising a premixing step of In and Sb precursors at a temperature of less than 100°C, under stirring.

IPC Classes  ?

• C09K 11/74 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing arsenic, antimony or bismuth

Abstract

The proposed recovery device comprises a stator (11), a slide (12), return means (13), a supporting platform (14), a chassis (15) and an electrical pulse integration circuit (16). It constitutes a magnetically bistable device which, by construction, is able to ensure that the amount of energy collected by integration of each electric pulse it generates is controlled and substantially constant. It has higher performance than previous solutions, is easily adaptable in dimensions, and has a manufacturing and maintenance cost that is low enough that it can be produced on an industrial scale and deployed widely.

IPC Classes  ?

• H02K 35/02 - Generators with reciprocating, oscillating or vibrating coil system, magnet, armature or other part of the magnetic circuit with moving magnets and stationary coil systems
• H02K 1/34 - Reciprocating, oscillating or vibrating parts of the magnetic circuit
• H02K 35/04 - Generators with reciprocating, oscillating or vibrating coil system, magnet, armature or other part of the magnetic circuit with moving coil systems and stationary magnets
• H02K 7/18 - Structural association of electric generators with mechanical driving motors, e.g.with turbines

Abstract

The present invention [relates to] a regulation system (28) for a multi-active bridge converter (10) with hybrid supply, comprising: an input current port (20) comprising an H-shape switch bridge (30) having a switch (T1) controlled by a first law having a first duty cycle, at least one output voltage port (22, 24) comprising an H-shape switch bridge (38, 40), one switch (T 21, T 31) of which is controlled by a second law which is phase-shifted with respect to the first law, the regulation system (28) regulates the converter (10) to a setpoint comprising a setpoint current value for the current of the current port (20) and a setpoint voltage value for a voltage port (22, 24).

IPC Classes  ?

• H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

Abstract

The invention relates to a device (1) and a system for tomography of the lungs (20), the device comprising a support member (10), and at least five transceivers (11) attached to the support member (10) configured to transmit and receive an ultrasonic wave of variable frequency over a frequency range, the transceivers (11) being arranged in at least two first assemblies (110) each facing a lung (20) of a human or animal body (2). The associated tomography method comprises transmitting and receiving the ultrasound wave according to transmission and reception profiles, by the transceivers (11), and analysing the deformation between these profiles in order to obtain the speed of the wave as a function of the frequency and direction of propagation of the wave, and constructing a tomogram on the basis of an item of data relating to this speed.

IPC Classes  ?

• A61B 8/08 - Clinical applications
• A61B 8/15 - Transmission-tomography
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 8/13 - Tomography

Abstract

A resistive memory cell includes a lower electrode based on one of the following materials: titanium nitride TiN, tantalum nitride TaN, tantalum Ta, copper Cu, tungsten W, platinum Pt, gold Au or silver Ag, an upper electrode, an active layer having a first contact surface with the lower electrode and a second contact surface with the upper electrode, the active layer including a zone, referred to as the local zone, the local zone being made of a material including vanadium, oxygen and Ti or Ta or Cu or W or Pt or Au or Ag, the local zone extending from the first contact surface, the rest of the active layer being made of conductive vanadium oxide.

IPC Classes  ?

• H10N 70/00 - Solid-state devices having no potential barriers, and specially adapted for rectifying, amplifying, oscillating or switching
• H10B 63/00 - Resistance change memory devices, e.g. resistive RAM [ReRAM] devices

Abstract

The invention relates to an optoelectronic device (1) for on-demand deformation of a crystalline semiconductor portion (10), comprising: o a deformation structure (20), comprising: a structured thin film (23) having two arms (23.1) suspended above a cavity; o the crystalline semiconductor portion (10), resting on the two arms (23.1); o a waveguide (2) optically coupled to the crystalline semiconductor portion (10); o an electrical deformation device, suitable for deforming the crystalline semiconductor portion (10) and comprising: an electrical power source suitable for generating an electrical control signal; and an electrical circuit (31, 32, 33, 34; 35, 36) suitable for generating, in response to the electrical control signal, an electric field or a temperature field in the arms (23.1) which induces a deformation of the arms (23.1) and therefore of the crystalline semiconductor portion (10).

IPC Classes  ?

• H01L 33/02 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies
• H01L 33/10 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a light reflecting structure, e.g. semiconductor Bragg reflector
• H01S 5/00 - Semiconductor lasers

Abstract

The invention relates to a method for the early in vitro diagnosis of a neurodegenerative disease in a human or an animal subject, the method comprising the step of detecting the presence of at least one marker chosen from among forms derived from amyloid beta peptides (Aβ) chosen from among the oligomers of these peptides and the prefibrillar and fibrillar aggregate forms of these peptides, and forms derived from phosphorylated tau proteins chosen from among the hyperphosphorylated forms of these proteins, the aggregate forms of these proteins and the modified phosphorylated tau proteins resulting from one or more post-translational modifications, the presence of the one or more markers being detected in a stool sample from this subject.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The method is for the discriminant monitoring of a composite multi-material assembly (1) having at least one internal layer (10) made of a first, electrically conductive composite material and a second layer (11) made of a second, electrically insulating composite material, the second layer (11) covering the first internal layer (10). The method includes: —preparing the composite multi-material assembly (1) by exposing a portion (101) of the internal layer (10), which constitutes a first electrode; —applying a second electrode (103) to the surface of the second layer (11), one of these electrodes (103) being earthed; —performing discriminant monitoring wherein a current is generated between the first electrode (101) and the second electrode (103) by applying a threshold voltage Us predetermined by calibration to characterize a lack of structural defects, the appearance of a breakdown at a voltage lower than the threshold voltage Us being indicative of the presence of at least one structural defect in the composite assembly (1).

IPC Classes  ?

• G01B 7/24 - Measuring arrangements characterised by the use of electric or magnetic techniques for measuring the deformation in a solid, e.g. by resistance strain gauge using change in magnetic properties
• B33Y 40/00 - Auxiliary operations or equipment, e.g. for material handling

Abstract

This classification device (1) has a pre-processing stage (10), an identification stage (30), and a material system (20) interposed between the pre-processing stage and the identification stage. The material system (20) comprises an inhomogeneous magnetic medium (50), which is subdivided into a plurality of zones (51), each zone being in magnetic communication with at least one neighbouring zone through a coupling link (53). According to the invention, the material system (20) further comprises a control means (71, 73) for setting the coupling value of each coupling link.

IPC Classes  ?

• G06N 3/044 - Recurrent networks, e.g. Hopfield networks
• G06N 3/065 - Analogue means
• G01R 33/12 - Measuring magnetic properties of articles or specimens of solids or fluids

Abstract

An electronic system includes an electronic device having a stack of layers, the stack including a first electrode, a subassembly with electrically controllable remanent states, a two-dimensional electron gas, a magnetic subassembly comprising at least one magnetic layer, and a second electrode having two first contacts and a second contact. The system also includes a writing device writing remanent states by applying an electric field between the two electrodes, and a Hall-effect reading device reading the remanent state by applying a current between the two first contacts and by measuring the voltage between the second contact and a reference potential.

IPC Classes  ?

• H10N 52/00 - Hall-effect devices
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H10N 50/10 - Magnetoresistive devices
• H10N 50/20 - Spin-polarised current-controlled devices

Abstract

A method is disclosed for processing photoacoustic images, this method including: obtaining a time series of images of a sample, the images being acquired by a photoacoustic imaging system at Mx excitation-pulse wavelengths, with N images acquired per wavelength; performing multispectral spatio-temporal filtering via singular value decomposition applied to all of the N*Mx acquired images so as to obtain N*Mx filtered images; for each wavelength, computing a filtered variance image based on the N filtered images, a pixel of coordinate r in the filtered variance image being equal to the variance of the distribution of the values of pixels of same coordinate r in the filtered images obtained for this wavelength; and correcting the filtered variance image by subtracting a variance of the residual electronic noise after the multispectral spatio-temporal filtering has been performed, the noise being produced by the sensors of ultrasonic waves of the photoacoustic imaging system.

IPC Classes  ?

• G06T 7/00 - Image analysis
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
• G06T 5/70 - DenoisingSmoothing

Abstract

A novel RFID communication device is proposed which allows the detection and electronic processing not only of the response signal backscattered at the fundamental frequency f0 of the reader, but also at least one response signal backscattered at a harmonic frequency, before feeding them to the conventional receive chain of an RFID reader. The joint use of the signal at the fundamental frequency of the reader and at least one signal at a harmonic frequency allows the reader's performance to be improved. The RFID reader can additionally be provided with novel functionalities by virtue of suitable software processing. It is applicable to the field of communications between a reader and passive transponders in UHF RFID and to the field of the Internet of Things.

IPC Classes  ?

• G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation

Abstract

The present invention relates to an electronic device comprising: a first electrode comprising a contact, a ferroelectric subassembly having a ferroelectric polarization, a spin polarization subassembly which spin-polarizes an incident current and comprises a layer of ferromagnetic or ferrimagnetic material, an interfacing subassembly which is arranged between the two subassemblies and converts the spin current into a charge current, the ferroelectric subassembly and the interfacing subassembly having a contact, and a second electrode which comprises two contacts and delimits the polarization subassembly, the contact of the first electrode changing the state of polarization by applying a potential difference between this contact and another contact.

IPC Classes  ?

• H10N 50/20 - Spin-polarised current-controlled devices
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H01L 29/66 - Types of semiconductor device
• H10N 50/85 - Materials of the active region

Abstract

A method for manufacturing an image projection device for projecting an image onto an eye, includes an emission surface S. The surface S comprises a set of waveguides, a set of diffraction gratings and a set of electrodes. Each grating is positioned at the intersection of one of the guides and one of the electrodes so as to form an emission point for a light wave, the set of waveguides being arranged in a waveguide configuration, and the set of electrodes being arranged in an electrode configuration. The method comprises a phase of designing the device and a phase of physically manufacturing the device thus designed. The design phase comprises the step consisting in determining the waveguide configuration or the electrode configuration, the determined configuration being a non-rectilinear isoline configuration defined in the plane defined by the emission surface S and generating an aperiodic distribution of the emission points.

IPC Classes  ?

• G02B 27/01 - Head-up displays

Abstract

A pancreatic cell receiving matrix including a semi-permeable wall and a porous body including a first set of cavities including pancreatic cells, and a second set of cavities free of pancreatic cells. The first set of cavities and the second set of cavities are not fluidically connected to one another. The cavity or cavities left free of cells create paths for the nutrients and gases to diffuse in the matrix, and they form a nutrient and gas reserve area in the matrix. The matrix limits and preferably prevents nutrient and gas depletion of the pancreatic cells. Their mortality is therefore reduced, allowing better insulin delivery.

IPC Classes  ?

• A61L 27/38 - Animal cells
• A61F 2/02 - Prostheses implantable into the body
• A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
• A61L 27/20 - Polysaccharides
• A61L 27/56 - Porous or cellular materials

Abstract

A method for detecting a lytic activity of one or more types of phages or of the activity of one or more antibiotics with respect to a bacterial strain, the method including using a first multiwell plate, each well receiving a sample containing phages or antibiotics, making at least one deposit on a transparent area of a support, the deposit containing bacteria of the bacterial strain, applying the first plate against the support so that each sample in each well comes into contact with the deposit, for each well, determining, using the detection means, the activity or absence of activity of the phage or antibiotic with respect to the bacterial strain, taking into account the intensity of light signals transmitted through each well and/or the variation thereof over time.

IPC Classes  ?

• C12Q 1/18 - Testing for antimicrobial activity of a material
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 1/32 - Inoculator or sampler multiple field or continuous type
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage

Abstract

A method for converting an initial datum between a colour space of a first colorimetric system and a colour space of a second colorimetric system, the initial datum being formed of at least one element expressed in a colorimetric reference system, the method includes: converting the initial datum into a projected datum, by expressing the at least one element in the colour space of the first colorimetric system; adapting the projected datum into an adapted datum, by expressing the at least one element in the colour space of the second colorimetric system. The colour space of the first colorimetric system and of the second colorimetric system are each a hyperbolic space defined by a hyperbolic metric projective reference system.

IPC Classes  ?

• G09G 5/02 - Control arrangements or circuits for visual indicators common to cathode-ray tube indicators and other visual indicators characterised by the way in which colour is displayed
• G01J 3/28 - Investigating the spectrum
• H04N 17/00 - Diagnosis, testing or measuring for television systems or their details
• H04N 23/85 - Camera processing pipelinesComponents thereof for processing colour signals for matrixing

Abstract

The present invention relates to a method for carrying out pulsed charging of an energy storage element (4) comprising, in a first phase of a charging cycle (E1), commanding a voltage profile (VC) having voltage regulation-driven increments (S1, S2, S3, S4, S5) defining a current profile (IC) in a charging cycle of a predetermined duration, and wherein a voltage increment (S1, S2, S3, S4, S5) is computed at a voltage amplitude at the time of a calculation step i according to a function depending on an estimate of the no-load voltage and on an estimate of the internal resistance at said time, on a coefficient n defining the charging duration and on the nominal capacity of the storage element. The invention is applicable to the fast-charging protocol, in particular for electromobility applications.

IPC Classes  ?

• H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
• H02J 7/04 - Regulation of the charging current or voltage

Abstract

The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds. The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds. The present invention relates to the applications thereof, in particular in therapeutic treatment. The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds. The present invention relates to the applications thereof, in particular in therapeutic treatment. The present invention relates in particular to compound having the following structure: The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds. The present invention relates to the applications thereof, in particular in therapeutic treatment. The present invention relates in particular to compound having the following structure: The present invention relates to new tetrahydroquinoline (THQ) compounds and new methods for synthetizing such compounds. The present invention relates to the applications thereof, in particular in therapeutic treatment. The present invention relates in particular to compound having the following structure: wherein R, R′, RA, Nu, R1, R2, R3, and R4 are each independently an atom or a chemical group of atoms.

IPC Classes  ?

• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• A61K 31/4706 - 4-Aminoquinolines8-Aminoquinolines, e.g. chloroquine, primaquine
• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• A61K 31/695 - Silicon compounds
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• C07D 215/42 - Nitrogen atoms attached in position 4
• C07D 215/48 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
• C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07F 7/18 - Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
• C07F 11/00 - Compounds containing elements of Groups 6 or 16 of the Periodic Table

Abstract

The present invention relates to a tangible control device (10) for controlling a variable datum, comprising an interface (11) capable of rotating about a central axis for a first variable datum control, this interface comprising a frame (12) and a slider (13) supported by the frame (12), the slider being movable along the frame (12) for a second variable datum control. The frame (12) comprises a series of segments (20a, 20b, 20c, 20d), each segment being hinged with the segment adjacent thereto by means of a hinge pin to permit an angular movement of one segment with respect to the other. The tangible control device (10) comprises an electromechanical actuator (40) for driving the variable geometry that comprises an electric motor and a cascade of gears.

IPC Classes  ?

• G06F 3/0354 - Pointing devices displaced or positioned by the userAccessories therefor with detection of 2D relative movements between the device, or an operating part thereof, and a plane or surface, e.g. 2D mice, trackballs, pens or pucks
• G06F 3/0362 - Pointing devices displaced or positioned by the userAccessories therefor with detection of 1D translations or rotations of an operating part of the device, e.g. scroll wheels, sliders, knobs, rollers or belts

Abstract

The method for imaging an object to be imaged includes: generating, using a lighting device (2), a series of illumination patterns; for each illumination pattern, carrying out a stimulating phase in which translations of the illumination pattern are carried out over an entrance of a square-core multimode optical fiber (4) by means of at least one translating device (3a) of an optical system (3) placed between the lighting device (2) and the entrance of the square-core multimode optical fiber (4), the translations being carried out in a plane parallel to the entrance plane of the square-core multimode optical fiber (4); for each stimulating phase, carrying out an acquiring phase in which the signal generated by the illumination pattern on the object to be imaged (O) placed at the exit of the square-core multimode optical fiber (4) is measured by a signal-measuring device (5; 9); and reconstructing, using a computing device (6), by the signal measured in each acquiring phase, the object to be imaged.

IPC Classes  ?

• A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
• A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances
• A61B 1/07 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

A sensor device including a conductive graphene film covered on at least one side by a graphene support layer of parylene, a detection element configured to sense an environmental change, and an electrode. The parylene repairs some defects of the conductive graphene film without damaging, polluting, or degrading the conductivity of conductive graphene film.

IPC Classes  ?

• C01B 32/186 - Preparation by chemical vapour deposition [CVD]
• B32B 27/12 - Layered products essentially comprising synthetic resin next to a fibrous or filamentary layer
• C01B 32/194 - After-treatment
• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
• G06F 3/042 - Digitisers, e.g. for touch screens or touch pads, characterised by the transducing means by opto-electronic means

Abstract

The invention relates to a method for the primary control of an inverter interfacing an intermittent energy source and an AC power grid. Through each of its various aspects, the invention proposes a novel droop command and control loop or droop control loop (5) that adapts to the variations in active power available at the inverter (1). This loop may advantageously be implemented on each inverter that, among a plurality of generators connected to the grid, interfaces an intermittent energy source (2), while at the same time guaranteeing: a. correct allocation of active power among the generators, and b. correct signalling, via the frequency at the point of connection of each generator to the grid, of the fact that each generator has reached its active power limits, thereby allowing protective measures to be activated so that each generator of the plurality returns to its active power range.

IPC Classes  ?

• H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
• H02J 3/48 - Controlling the sharing of the in-phase component

Abstract

1234232213131218188-alkyl group being optionally substituted, n being an integer comprised between 1 and 4 (preferably equal to 1), They exhibit high cytotoxicity against cancer cells.

IPC Classes  ?

• C07D 233/64 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
• C07D 235/12 - Radicals substituted by oxygen atoms
• C07D 263/32 - Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07D 277/24 - Radicals substituted by oxygen atoms
• A61P 35/00 - Antineoplastic agents
• A61K 31/4164 - 1,3-Diazoles

Abstract

The method p1 for converting osmotic energy into hydraulic energy and the method p2 for desalination, include pressurisation/depressurisation and isochoric washing of an aqueous solution containing a salt in the presence of a selective hydrophobic nanoporous material of which the nanoporous volume within the material is only accessible to fresh water and which has a nanoporosity volume fraction ranging from 0.2 to 1 so as to convert osmotic energy into hydraulic energy or conversely to desalinate water, preferably sea water or brine.

IPC Classes  ?

• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 103/08 - Seawater, e.g. for desalination
• F03G 7/00 - Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for

Abstract

A device including a first portion, a second portion, a first contact and a second contact, the first portion being made of a semiconductor having a first doping, the second portion being made of a semiconductor having a second doping different than the first, the first portion and the second portion forming a p/n junction including a depletion zone in the first portion, the contacts being configured so that when an electric voltage (V1) is applied between the contacts, a dimension of the depletion zone depends on a value of the electric voltage, an ionization energy being defined for dopants of the second portion. The device includes an emitter generating a radiation having an energy greater than the ionization energy and illuminating the second portion with the radiation.

IPC Classes  ?

• H01L 33/00 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof
• H01L 33/34 - Materials of the light emitting region containing only elements of group IV of the periodic system

Abstract

A method for preparing a microelectronic component includes cleaning of the surface of an exposed layer with a basis of a III-V material by a cyclic plasma treatment, each cycle comprising a purge phase and a plasma treatment phase. During the formation of the plasma, a bias voltage is applied to the substrate. The method further includes depositing, on the cleaned surface, a subsequent layer. The method provides an optimal cleaning of the exposed layer while minimising, and preferably avoiding degradation of the structure. The preparation method thus makes it possible to improve the quality of the interface between the layer with a basis of a III-V material and the subsequent layer. The electrical properties of the component are consequently improved.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• H01L 33/00 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof

Abstract

The present description concerns a method of identification of risks of cyberattacks on a programmable logic controller, the method comprising: the generation of a digital representation of a minimized finite-state transducer based on a specification of a controller logic of the programmable logic controller, the minimized finite-state transducer comprising a set of source states, a set of destination states, and a set of transitions from a source state to a destination state based on an input data value; the generation of a second computer file, based on a first computer file identifying a subset of sensitive states, the second file comprising a list of critical transitions associated with the sensitive states, and for each transition, a list of the input data; and the generation of a fourth computer file indicating input data to be protected which are both associated with critical transitions and with a corruption risk.

IPC Classes  ?

• G06F 21/57 - Certifying or maintaining trusted computer platforms, e.g. secure boots or power-downs, version controls, system software checks, secure updates or assessing vulnerabilities

Abstract

The present invention relates to the novel compounds of general formula (I) as defined below. The invention further relates to a pharmaceutical composition comprising said compound of formula (I). The invention further relates to said compound of general formula (I) as defined below for use as medicament in the treatment of an autotaxin (ATX) related disease.

IPC Classes  ?

• C07D 405/10 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
• A61K 31/404 - Indoles, e.g. pindolol
• A61P 25/00 - Drugs for disorders of the nervous system

Abstract

Security lighting device (1) comprising a front face (3) for displaying a pictogram, a rear face and at least one thick wall (5) extending between the front face and the rear face, said security lighting device comprising first light means designed to illuminate the front face (3), said lighting device (1) being characterized in that it further comprises second light means installed on said at least one thick wall (5), said second light means being chosen such that the emitted light has a combination of colour and/or form adapted to influence the decision of the user on the chosen direction of evacuation according to their position in the environment.

IPC Classes  ?

• G09F 19/18 - Advertising or display means not otherwise provided for using special optical effects involving the use of optical projection means, e.g. projection of images on clouds
• G09F 13/04 - Signs, boards, or panels, illuminated from behind the insignia
• G09F 9/37 - Indicating arrangements for variable information in which the information is built-up on a support by selection or combination of individual elements in which the desired character or characters are formed by combining individual elements being movable elements

Abstract

The present invention relates to a reading circuit (10) having differential amplification comprising: • a. a resistive component (12) having discrete states corresponding to different resistance values of the resistive component (12); • b. a reading block (14) for reading the state of the resistive component (12) by comparing the resistance value of the resistive component (12) with the resistance value of a reference component, the reading block (14) having a reading current flowing through it; and • c. a control block (16) which is configured to generate an additional current and add said additional current to the reading current in order to obtain a resulting current flowing through the resistive component.

IPC Classes  ?

• G11C 29/02 - Detection or location of defective auxiliary circuits, e.g. defective refresh counters
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• G06F 7/58 - Random or pseudo-random number generators
• G11C 14/00 - Digital stores characterised by arrangements of cells having volatile and non-volatile storage properties for back-up when the power is down

Abstract

Security lighting device (1) comprising a front face (3) for displaying a pictogram, a rear face and at least one thick wall (5) extending between the front face and the rear face, said security lighting device comprising first light means designed to illuminate the front face (3), said lighting device (1) being characterized in that it further comprises second light means installed on said at least one thick wall (5), said second light means being controlled such that the emitted light has a flashing frequency of between 5 Hz and 24 Hz adapted to influence the decision of the user on the chosen direction of evacuation.

IPC Classes  ?

• G09F 13/04 - Signs, boards, or panels, illuminated from behind the insignia
• G09F 9/37 - Indicating arrangements for variable information in which the information is built-up on a support by selection or combination of individual elements in which the desired character or characters are formed by combining individual elements being movable elements
• G09F 19/22 - Advertising or display means on roads, walls or similar surfaces, e.g. illuminated

Abstract

The invention relates to compounds of general formula (I): for use for treating an adrenocorticotropin hormone (ACTH)-dependent Cushing's syndrome, wherein R1is H or a -C(O)-R9, wherein R9133 linear or branched, saturated or unsaturated, alkyl group; R2is H or a halogen; R3is a halogen; R4and R8are, independently, H or a halogen, R5133, linear or branched, saturated or unsaturated, alkyl group, OH, or a halogen; R6610133 linear or branched, saturated or unsaturated, alkyl group; R713261010 aryl group, Ar being optionally substituted with a halogen, wherein if R2is H, then at least one of R5, R6, R7and R8 is not H,or one of its pharmaceutically acceptable salts.

IPC Classes  ?

• A61K 31/609 - Amides, e.g. salicylamide
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 5/06 - Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The invention relates to a system and a method for computer-aided detection (CAD) of aggressive prostate cancers. The automatic diagnosis of aggressive prostate cancers is difficult and methods that work with some MRI scanners do not work as well when implemented on images from different scanners. By studying a data base containing MRI data and biopsy results from 265 patients, acquired by 4 different types of MRI scanners, using machine learning techniques, the inventors established a method for automatically determining the presence of aggressive cancers, this methods showing high sensitivity and specificity when implemented on another database containing MRI data from 270 patients, acquired by different MRI scanners than the first database. The method involves feeding MRI images to a system calculating a score for a portion of the prostate and determines that the portion contains an aggressive cancer based on whether a criterion depending on the score is verified.

IPC Classes  ?

• G06T 7/00 - Image analysis

Abstract

The present invention concerns a quantum processing system (1) configured to implement a transversal action of a logical T gate on a triply even quantum code (Q1) or a triply even quantum polar code (Q2) encoding K logical qubits into N physical qubits wherein the logical T gate is a tensorproduct of K elementary logical gates acting on the corresponding K logical qubits.

IPC Classes  ?

• G06N 10/70 - Quantum error correction, detection or prevention, e.g. surface codes or magic state distillation
• G06N 10/20 - Models of quantum computing, e.g. quantum circuits or universal quantum computers

Abstract

The invention relates to new cell-penetrating peptides comprising or consisting of an amino acid sequence selected from the sequences SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8. The invention further relates to fusion proteins comprising said peptides and a molecule of pharmaceutical, diagnostic or biotechnological interest.

IPC Classes  ?

• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61P 35/00 - Antineoplastic agents
• C07K 14/05 - Epstein-Barr virus
• C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses

Abstract

According to an aspect, the present description is related to an apparatus for depositing on a substrate drops of a specimen sample including a liquid medium and living microorganisms. The apparatus includes a tray for supporting the substrate, a container, e.g. a syringe, configured to receive a volume of the specimen sample and a drop deposition motor configured to push the specimen sample out of the container to form drops of a predetermined volume that detach by gravity and fall on the substrate. The apparatus further includes guiding motors configured for changing a relative position of the tray and the container and a control unit configured to synchronize the drop deposition motor and the guiding motors in order to deposit drops on the substrate according to a pattern.

IPC Classes  ?

• C12Q 1/06 - Quantitative determination
• C12M 1/42 - Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave

Abstract

A transdermal dihydrogen delivery device including a body including an anode and a cathode, and an electrical energy source, wherein the body is based on a flexible material, capable of shaping to the skin of a human or animal body, and the body includes a water receptacle, the relative arrangement of the receptacle, the anode and the cathode being configured such that the water contained in the receptacle is in contact with the anode and the cathode to form a closed electrical circuit, so as to produce dihydrogen at the cathode from the water taken from the receptacle, to release transdermally the dihydrogen produced. The proposed delivery device is relatively non-invasive, while allowing dihydrogen delivery.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61N 1/04 - Electrodes

Abstract

nkk) defined by a frequency range, for which a value representative of the power spectral density of the signal (x) is greater than a percentage (A) of its average value.

IPC Classes  ?

• G01N 29/024 - Analysing fluids by measuring propagation velocity or propagation time of acoustic waves
• G01N 29/34 - Generating the ultrasonic, sonic or infrasonic waves
• G01N 29/44 - Processing the detected response signal

Abstract

A nanocrystal particle includes a Group III-VI compound including gallium and sulfur, wherein the nanocrystal particle is configured to emit a first light, a maximum emission peak of the first light is in a wavelength range of greater than or equal to about 300 nanometers and less than or equal to about 485 nanometers, an absolute quantum efficiency of the nanocrystal particle is greater than or equal to about 26%, and a full width at half maximum of the maximum emission peak of the first light is greater than or equal to about 10 nanometers and less than or equal to about 70 nanometers, when analyzed by photoluminescence spectroscopy.

IPC Classes  ?

• C09K 11/64 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing aluminium
• C09K 11/62 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing gallium, indium or thallium
• G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
• H10K 50/115 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising active inorganic nanostructures, e.g. luminescent quantum dots
• H10K 59/38 - Devices specially adapted for multicolour light emission comprising colour filters or colour changing media [CCM]

Abstract

A method may activate a fuel cell including a plurality of electrochemical cells in a stack, the fuel cell being intended to operate, during at least one nominal operating phase, as an electric generator. Such a method may include, during an activation phase by electrolysis, prior to the at least one nominal operating phase: electrically supplying the fuel cell by an external electric generator, the electric supply being configured to apply an activation voltage greater than the voltage of the cell in an open circuit (OCV); fluid supplying a humid gas fluid at a first electrode and/or a second electrodes. The humid gas may have a relative humidity (RH) such that 40%≤RH<100%. The fuel cell may operate in electrolysis during the activation phase called by electrolysis.

IPC Classes  ?

• H01M 8/04225 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids during start-up or shut-downDepolarisation or activation, e.g. purgingMeans for short-circuiting defective fuel cells during start-up
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 4/96 - Carbon-based electrodes
• H01M 8/04089 - Arrangements for control of reactant parameters, e.g. pressure or concentration of gaseous reactants
• H01M 8/04119 - Arrangements for control of reactant parameters, e.g. pressure or concentration of gaseous reactants with simultaneous supply or evacuation of electrolyteHumidifying or dehumidifying
• H01M 8/04223 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids during start-up or shut-downDepolarisation or activation, e.g. purgingMeans for short-circuiting defective fuel cells
• H01M 8/04828 - HumidityWater content
• H01M 8/0656 - Combination of fuel cells with means for production of reactants or for treatment of residues with means for production of gaseous reactants by electrochemical means
• H01M 8/1004 - Fuel cells with solid electrolytes characterised by membrane-electrode assemblies [MEA]

Abstract

An antisense oligonucleotides having the ability to decrease the expression level of the huntingtin protein in glioma cells, for their use in sensitizing the cells to an anti-cancer treatment.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 31/166 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
• A61K 31/175 - Amides, e.g. hydroxamic acids having the group N—C(O)—N or N—C(S)—N, e.g. urea, thiourea, carmustine having the group , N—C(O)—N=N— or , e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazonesThioanalogues thereof
• A61K 31/282 - Platinum compounds
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed is a method to fabricate a magnetic device (4) from a dielectric layer (3) having a through-hole, so called "via", the method comprising: • - forming a tunnel junction (41) on the dielectric layer (3) comprising: • - a first magnetic layer, intended to form a said "free layer" (411); and • - a second magnetic layer, intended to form a said "reference layer" (412), • - an insulator layer, intended to form a "tunnel barrier" (413); the free layer (411) or the reference layer (412) being located in the via and being surrounded by the dielectric layer (3).

IPC Classes  ?

• H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
• H10N 50/01 - Manufacture or treatment
• H10N 50/10 - Magnetoresistive devices
• H10N 50/80 - Constructional details

Abstract

A magnetic tunnel junction (3) is disclosed which includes a synthetic antiferromagnetic free layer structure (30) comprising a magnetic core (32) and a magnetic shell (31), the magnetic core comprising a magnetic layer (321) having an aspect ratio between 0.5 and 2, the magnetic shell surrounding the magnetic core at least partially along its thickness, and the magnetization of the magnetic shell being antiferromagnetically coupled with the magnetization of the magnetic core. A corresponding fabrication method is also disclosed.

IPC Classes  ?

• H10N 50/10 - Magnetoresistive devices
• H10N 50/01 - Manufacture or treatment
• H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices

Abstract

A computer-implemented method for memory management in a computer system configured for generating a signature of a binary data message m using a key B of a predetermined lattice-based structure is proposed, which comprises: determining coefficients of a 2×2 signature generation matrix SG, wherein the non-diagonal coefficients of the signature generation matrix SG are complex polynomials with a non-zero imaginary part, and the diagonal coefficients of the signature generation matrix SG are real polynomials; and determining a LDL representation of the signature generation matrix SG according to which SG is represented by a matrix product L.D.L*, wherein L is a 2×2 lower triangular matrix with ones on the diagonal, D is a 2×2 diagonal matrix, and L* is the adjoint of L; wherein the storing in a memory buffer of the computer system of the coefficients of the signature generation matrix SG and the coefficients of the matrices of the LDL representation is managed based on that the signature generation matrix SG has real diagonal coefficients, and the memory buffer is used alternatively to store the coefficients of the signature generation matrix SG or the coefficients of the matrix D of the LDL representation.

IPC Classes  ?

• H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system

Abstract

Disclosed are crystalline hafnium oxide nanoparticles, a method for manufacturing same, and the uses thereof. The invention relates to crystalline hafnium oxide nanoparticles, characterized in that they bear amide molecules and/or at least one amide degradation product chosen from a carboxylic acid, an amine or an amino acid and/or residues of said molecules on their surface.

IPC Classes  ?

• C01G 27/00 - Compounds of hafnium

Abstract

The present application relates to ceramic/polymer hybrid solid electrolytes with improved interfacial strength, comprising a surface-dehydrated pre-treated ceramic.

IPC Classes  ?

• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 10/052 - Li-accumulators
• H01M 6/18 - Cells with non-aqueous electrolyte with solid electrolyte