Abstract

The subject matter of the present application is a Multifunctional Integrated Security Module (MMSI), which is a structure that combines high-tech equipment in a new arrangement for monitoring, vehicle recognition and emergency detection, for use in the public/non-public security system. Current security solutions are characterised by equipment operating in an isolated or partially integrated manner, without providing the uniform architecture needed by public security and social defence agencies. The MMSI is innovative in that it integrates real-time video monitoring functions, with super wifi guaranteeing a stable and fast connection for data transmission and 4G/5G communication, allowing remote access via mobile devices, with solar energy guaranteeing autonomy in places where the power supply is limited or non-existent, a radar making it possible to detect vehicle movements, and is equipped with artificial intelligence mechanisms, and an emergency button allowing immediate security measures to be activated. It is made from a flame-retardant, non-electrically conductive and anti-corrosive material, safe for equipment and people and suitable for use in harsh environments. Its main use is in places with high security needs (public roads, condominiums, schools, hospitals and shopping centres).

IPC Classes  ?

• G08G 1/017 - Detecting movement of traffic to be counted or controlled identifying vehicles
• G08B 29/16 - Security signalling or alarm systems, e.g. redundant systems
• E04H 12/08 - Structures made of specified materials of metal
• E04H 12/34 - Arrangements for erecting or lowering towers, masts, poles, chimney stacks, or the like
• H02S 20/20 - Supporting structures directly fixed to an immovable object
• H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast

Abstract

The present invention describes the preparation of heterogeneous catalysts of mixed oxides based upon niobium and mixed oxides of zinc, manganese, nickel, cobalt and/or aluminum, originating from hydrotalcites (HTs) as precursor phase of heterogeneous catalysts, and application thereof in the chemical recycling of poly(ethylene terephthalate) (PET) for the production of metal free bis(hydroxy)ethylene (BHET) monomers and oligomers having a processing performance similar to that of the homogeneous catalysis system.

IPC Classes  ?

• C08J 11/26 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing carboxylic acid groups, their anhydrides or esters
• B01J 23/06 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of zinc, cadmium or mercury
• B01J 23/34 - Manganese
• B01J 23/755 - Nickel
• B01J 23/889 - Manganese, technetium or rhenium
• B01J 23/00 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group
• B01J 23/20 - Vanadium, niobium or tantalum
• B01J 23/75 - Cobalt
• C08G 63/183 - Terephthalic acids
• B01J 35/02 - Solids
• C07C 67/02 - Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification

Abstract

A non-transitory computer-readable medium may contain instructions. The instructions may direct the processor to: obtain a mathematical expression of Steiner patch that is part of a tessellation approximation of a three-dimensional (3D) object to be printed by a 3D printer, together with a height value of a slicing plane, determine an approximate mathematical expression of a Rational Quartic Bézier (RQB) curve, the RQB curve being an intersection of the slicing plane and the Steiner patch and generate 3D printing points in Euclidean space for the object based upon the approximate mathematical expression of the RQB, the 3D printing points for 3D printing of the 3D object.

IPC Classes  ?

• G06T 17/30 - Surface description, e.g. polynomial surface description
• G06T 7/11 - Region-based segmentation
• B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes

Abstract

A method for generating 3D printing points may include obtaining a Steiner patch that is part of a tessellation approximation of the 3D object, determining a parametric curve of a slicing plane and the Steiner patch, determining a classification of the parametric curve, sampling, based upon the classification, first and second points spaced by a parametric spacing along the parametric curve, determining a Euclidean spacing of the first and second points, and comparing the Euclidean spacing to a predefined spacing threshold. In response to the Euclidean spacing failing to satisfy the predefined threshold, sampling a third point along the parametric curve between the first and second points, generating 3D printing points in Euclidean space for the object based upon the first point, second point and third point sampled along the parametric curve.

IPC Classes  ?

• G06T 17/20 - Wire-frame description, e.g. polygonalisation or tessellation

Abstract

An example adapter device includes a host-side connector to connect to a host device, the host-side connector including a host-side electrical contact to connect to a corresponding electrical contact of the host device. The adapter device further includes a storage-side connector to connect to storage devices operable under different protocols, the storage-side connector including a storage-side electrical contact to connect to a connected storage device. The adapter device further includes a circuit to apply a bias voltage to the host-side electrical contact. The host-side electrical contact is to provide a protocol-indicating voltage to indicate to the host device a protocol of the connected storage device. The protocol-indicating voltage is dependent on the connected storage device's influence on the bias voltage.

IPC Classes  ?

• G06K 9/62 - Methods or arrangements for recognition using electronic means
• G06N 3/02 - Neural networks

Abstract

According to examples, an apparatus may include a processor and a non-transitory computer readable medium on which is stored instructions that may cause the processor to create a 2D reference mesh for an image of a curved visual mark, establish correspondences between finder pattern points in the curved visual mark and points of the 2D reference mesh, and determine a curved 3D mesh having a radius that results in a minimal reprojection error of a projective transform estimated for correspondences between the 2D reference mesh and the curved 3D mesh while the radius remains below a predefined upper limit. The instructions may also cause the processor to sample components of the curved visual mark in elements of the determined curved 3D mesh to form a 2D planar image of the curved visual mark and analyze the 2D planar image of the curved visual mark to read the curved visual mark.

IPC Classes  ?

• G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
• G06T 7/30 - Determination of transform parameters for the alignment of images, i.e. image registration

Abstract

In example implementations, a method executed by a processor is provided. The method divides a computer generated three dimensional (3D) model of an object to be printed into a plurality of two dimensional slices. A plurality of arc segments to describe curved surfaces of each one of the plurality of two dimensional slices is estimated. Print instructions are generated that include the plurality of arc segments for each one of the plurality of two dimensional slices. The method loads the print instructions on a 3D printer to print the object in accordance with the print instructions.

IPC Classes  ?

• G06T 7/12 - Edge-based segmentation
• B29C 64/386 - Data acquisition or data processing for additive manufacturing

Abstract

An example of a non-transitory computer-readable medium storing machine-readable instructions. The instructions may cause the processor to receive a three-dimensional (3D) object representation and subdivide it into a triangular grid. Curved triangles may be calculated for triangles in the triangular grid. The triangles may be subdivided and differences calculated between corresponding sections of the curved triangles and the received 3D object representation.

IPC Classes  ?

• G06T 19/00 - Manipulating 3D models or images for computer graphics

Abstract

An example of a computer-readable medium is provided to store machine-readable instructions. The instructions may cause a processor to receive three-dimensional (3D) object representations of an object. The distance between points of a grid applied to 3D object representation and random points on the 3D object representation may provide a sampling error used in calculating a modeling accuracy between the 3D object representations.

IPC Classes  ?

• G06T 17/00 - 3D modelling for computer graphics
• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts

Abstract

The invention relates to the production of heterogeneous catalysts of mixed oxides based on niobium and mixed oxides of zinc, manganese, nickel, cobalt and/or aluminum, from hydrotalcites (HTs), as the precursor phase of heterogeneous catalysts, and to the application thereof in the chemical recycling of poly(ethylene terephthalate) (PET) for the production of metal-free bis(hydroxy)ethylene (BHET) monomers and oligomers with a process performance similar to that of the system in homogeneous catalysis.

IPC Classes  ?

• C08K 3/22 - OxidesHydroxides of metals
• C08J 11/24 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing hydroxyl groups
• C07C 63/26 - 1,4-Benzenedicarboxylic acid
• C08G 63/183 - Terephthalic acids
• C08G 63/83 - Alkali metals, alkaline earth metals, beryllium, magnesium, copper, silver, gold, zinc, cadmium, mercury, manganese, or compounds thereof

Abstract

According to examples, an apparatus may include a processor and a memory on which is stored machine readable instructions executable by the processor to: identify a slice height for direct slicing of a Non-Uniform Rational B-Spline (NURBS) model formed of surfaces by slicing planes. The instructions may cause the processor to slice the NURBS model to produce slices having the identified slice height and to adaptively subdivide surfaces of the NURBS model whose bounding boxes respectively intersect at least one of the slicing planes until the bounding boxes meet a predefined criterion. In addition, for each of the generated bounding boxes which meet the predefined criterion, the instructions may further cause the processor to determine sample points of the surface with which the bounding box corresponds and to store the sample points of the surfaces for printing.

IPC Classes  ?

• G06T 15/30 - Clipping
• G06T 17/10 - Volume description, e.g. cylinders, cubes or using CSG [Constructive Solid Geometry]

Abstract

The present patent application discloses a new and innovative method for purification of glycerol derivatives, by simulated moving bed chromatography. The method of the present patent application allows the separation of at least one glycerol derivative present in a feed solution. The glycerol derivatives purified by the method disclosed herein include dihydroxyacetone (DHA), hydroxypyruvic acid (HPA), glycolic acid (GCO), oxalic acid (OXA), mesoxalic acid (MEO), tartronic acid (TTA), glyceric acid (GCA), glyceraldehyde (GLA), glyoxalic acid (GOX) and unreacted glycerol. The presently disclosed method may be used with any simulated moving bed chromatographic apparatus, including but not limited to moving port and moving column systems.

IPC Classes  ?

• B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
• C07C 31/22 - Trihydroxylic alcohols, e.g. glycerol
• C07C 7/12 - Purification, separation or stabilisation of hydrocarbonsUse of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers
• C07C 59/06 - Glycolic acid
• C07C 59/19 - Pyruvic acid

Abstract

The present invention describes a simple, quick, economical and sustainable production process for producing lipid nanoparticles using a microwave reactor. The technology of the present invention allows one-pot production of said particles, in one or two steps and in a closed system. Said technology does not use organic solvents or large volumes of water. Said technology allows lipid nanoparticles to be produced for medicinal (therapeutic and/or diagnostic), cosmetic and nutritional purposes. By adjusting the main critical factors of the process, such as time, temperature and stirring efficiency (which are dependent on the dimensions of the magnetic bar, stirring speed and total volume of the formulation), it is possible to produce lipid nanoparticles with the intended features, such as: average size comprised between 30 and 900 nm, preferably between 60 and 300 nm; polydispersion between 0.05 and 0.5, preferably between 0.1 and 0.3; and modular zeta potential value between 10 and 50 mV, preferably between 20 and 40 mV.

IPC Classes  ?

• B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided forMaking microcapsules or microballoons
• A61K 9/51 - Nanocapsules
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves

Abstract

Disclosed is a process for retrieval of nucleotide sequence. The process includes mixing iron chloride tetrahydrate with iron (III) chloride hexahydrate in solution; adding ammonium hydroxide to the mixture and stirring to form maghemite nanoparticles; stirring the maghemite nanoparticles in a solution with an inorganic acid, a surfactant and a monomer precursor of a conducting polymer; initiating polymerization of the monomer by adding the inorganic acid and an oxidizing agent to the stirred solution and further stirring to yield Polyaniline/maghemite nanocomposites; adding the nanocomposites to an first aqueous solution of the nucleotide sequence and stirring so as to electrostatically interact the nanocomposites with the nucleotide sequence; and weakening the electrostatic interaction between the nanocomposite and the nucleotide sequence to recover the nanocomposite independently of the nucleotide sequence.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
• B01J 20/06 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group
• B01J 20/26 - Synthetic macromolecular compounds
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Abstract

Disclosed is a process for retrieval of nucleotide sequence. The process includes mixing iron chloride tetrahydrate with iron (III) chloride hexahydrate in solution; adding ammonium hydroxide to the mixture and stirring to form maghemite nanoparticles; stirring the maghemite nanoparticles in a solution with an inorganic acid, a surfactant and a monomer precursor of a conducting polymer; initiating polymerization of the monomer by adding the inorganic acid and an oxidizing agent to the stirred solution and further stirring to yield Polyaniline/maghemite nanocomposites; adding the nanocomposites to an first aqueous solution of the nucleotide sequence and stirring so as to electrostatically interact the nanocomposites with the nucleotide sequence; and weakening the electrostatic interaction between the nanocomposite and the nucleotide sequence to recover the nanocomposite independently of the nucleotide sequence.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• A21D 6/00 - Other treatment of flour or dough before baking, e.g. cooling, irradiating or heating
• A23C 3/00 - Preservation of milk or milk preparations
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
• B01J 20/26 - Synthetic macromolecular compounds
• B01J 20/06 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Abstract

The present invention describes benzylthiazolidinone derivatives and pharmaceutical compositions comprising the same; these compounds have shown activity in schizophrenia animal models, with the advantage of not causing the typical adverse effects of antipsychotic drugs, since they exhibited lower incidence of catatonia and weaker effects on motor coordination, when compared with other antipsychotic drugs, such as haloperidol and clozapine, and no central nervous system depression effect; the molecules showed an effect in models of apomorphine-induced climbing, ketamine-induced hyperlocomotion and in prepulse startle response inhibition. FPY-3 did not exhibit any toxic effects after 14 days of treatment, and is potentially useful for the treatment of schizophrenia.

IPC Classes  ?

• C07D 417/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia

Abstract

The invention, coffee grounds oil as stabilizing agent, relates to the use of oil extracted from coffee grounds, which is a waste product, as a stabilizing agent for polymer matrices exposed to ionizing radiation. Coffee grounds supply in average 11% oil. Films produced with oil in a polymer matrix have been shown to be homogeneous and stable against ionizing radiation, in a sterilization dose (25 kGy), when oil extracted from coffee grounds is added in a concentration of 0.5% by mass. Viscosimetric tests have shown approximately 67% protection of the polymer matrix with the above oil concentration. Mechanical tests have shown that neither rigidity (modulus of elasticity) nor mobility (elongation at break) of the chains were affected by gamma radiation when oil extracted from coffee grounds was added to the composition.

IPC Classes  ?

• C08L 101/00 - Compositions of unspecified macromolecular compounds
• C08K 5/00 - Use of organic ingredients
• C08K 5/101 - EstersEther-esters of monocarboxylic acids
• C08K 13/08 - Ingredients of unknown constitution and ingredients covered by the main groups

Abstract

Alcohol concentration is gauged and graded on the basis of the absorption and reflection of electromagnetic waves in the radio frequency range (RF), with equipment suitable for use in the field and in production lines, in order to determine the amount of ethanol in the mixture, besides other components added to the mixture. The beverage to be tested goes through a specially designed transmission line. The measurement of absorption and reflection in the radio frequency range allows the alcohol concentration in the beverage to be more accurately determined, and is specially calibrated for ethanol. This appliance makes it possible to monitor alcohol concentration during the various production phases.

IPC Classes  ?

• G01R 27/26 - Measuring inductance or capacitanceMeasuring quality factor, e.g. by using the resonance methodMeasuring loss factorMeasuring dielectric constants
• G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance

Abstract

The present invention describes a polymer film that is totally water-soluble, hot or cold, which is produced from agar, a natural hydrocolloid polysaccharide widely used in the food industry. The agar has been modified by a hot reaction in acid medium. The change increased the dissolution capacity of the agar in aqueous medium without affecting the property thereof to form films in the presence of a plasticizing agent, since, in the original form thereof, the agar exhibits low solubility in water at ambient temperature and no other film exhibits rapid dissolution for use as a food-product vehicle system. The film produced will serve as support for the incorporation of natural, artificial and/or functional foodstuffs. It may be used, furthermore, in the pharmaceutical industry as a vehicle for active principles. The advantages of using the present film include, notably, the atoxicity and rapid elimination thereof, without metabolization by the organism, in addition to the simple production technology.

IPC Classes  ?

• C08L 5/12 - Agar-agarDerivatives thereof
• C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
• C08B 37/12 - Agar-agarDerivatives thereof
• C08B 30/14 - Cold water dispersible or pregelatinised starch
• C08B 15/00 - Preparation of other cellulose derivatives or modified cellulose
• C08K 5/53 - Phosphorus bound to oxygen bound to oxygen and to carbon only
• A23L 1/0532 - from seaweeds, e.g. alginates, agar, carrageenan

Abstract

The present invention relates to a vitreous material characterized by the ability to grow, in a controlled manner, nanostructured films on the surface thereof, on the basis of compounds of typically metallic elements included as dopants in the original composition thereof. The process begins with the automatic formation of nanoparticles on the surface of the material, grown using heat treatment as a function of parameters such as temperature, time and atmosphere type (reducing, neutral or oxidizing) resulting in metallic, oxide or mixed nanostructures, including the core-shell type. The type of doping is also chosen as a function of the applications of the material, which involve use as active substrates in electronic devices and processes, as active parts in sensors and dosimeters, in particular for detecting gases, including hydrogen, in heterogeneous catalysis and as active material for preparing stable nanoparticle solutions, including with size control. The nanoparticles that form the film may be removed when the material is treated with specific solvents, forming isolated nanoparticles after separation and drying of the solvent. The second important feature relates to the fact that the formation of nanostructures (nanoparticles or film) may be restarted any number of times, including following complete removal.

IPC Classes  ?

• B82B 1/00 - Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• B82Y 25/00 - Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
• C03C 21/00 - Treatment of glass, not in the form of fibres or filaments, by diffusing ions or metals into the surface
• H01F 10/32 - Spin-exchange-coupled multilayers, e.g. nanostructured superlattices
• H01B 1/16 - Conductive material dispersed in non-conductive inorganic material the conductive material comprising metals or alloys

Abstract

The present invention relates to oncology, in particular to a molecular compound denominated here as "oncoloose", which is capable of selectively destroying solid tumour cells without affecting rapidly replicating healthy cells. The present invention provides a product comprising a molecular compound denominated oncoloose, which is selectively targeted to the interior of tumours by means of a carboxylic group that neutralizes the negative electrical charge thereof, for transporting the acridine drug to the DNA in the tumour cells, preventing the replication thereof and causing apoptosis or cellular self-destruction of the tumour cells.

IPC Classes  ?

• C07D 219/00 - Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
• A61P 35/00 - Antineoplastic agents

Abstract

Thin ferromagnetic material. This invention patent relates to a ferromagnet consisting of a thin carbon film containing layers (1) of carbon chemically bonded to high-density polyethylene (2), the latter generating the unpaired electric charges that cause the ferromagnetism of this new material. In the present arrangement, the material synthesizing step takes only one hour, by means of an addition reaction of powder graphite (carbon source) (1) on a piece of high-density polyethylene (2) at a temperature of 60°C in a nitrogen or argon atmosphere.

IPC Classes  ?

• C08K 3/04 - Carbon
• C08K 5/04 - Oxygen-containing compounds
• C08L 23/06 - Polyethene
• C08G 77/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon
• B29B 13/10 - Conditioning or physical treatment of the material to be shaped by grinding, e.g. by trituratingConditioning or physical treatment of the material to be shaped by sievingConditioning or physical treatment of the material to be shaped by filtering
• B29C 70/58 - Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts comprising fillers only
• B32B 15/04 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance
• B05D 3/02 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by baking
• F25B 21/00 - Machines, plants or systems, using electric or magnetic effects
• G11B 5/64 - Record carriers characterised by the selection of the material comprising only the magnetic material without bonding agent
• H01F 1/00 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties
• H01F 10/00 - Thin magnetic films, e.g. of one-domain structure
• H01F 41/14 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for applying magnetic films to substrates
• H01B 1/24 - Conductive material dispersed in non-conductive organic material the conductive material comprising carbon-silicon compounds, carbon, or silicon
• C07D 333/18 - Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms

Abstract

The present invention relates to 3-acridinyl-methyl-thiazolidine-2,4-dione-derived compounds, also denominated thiazacridines, and to the related processes for chemically synthesizing same, and also to the therapeutic use thereof for treating cancer.

IPC Classes  ?

• C07D 277/08 - Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention has as an inventive step the production of fluorescent polyaniline nanoparticles via a specific process relating to a wet chemistry technique whereby polyaniline (PANI), an oxidizing agent and surfactants are combined, for minimizing problems resulting from aggression to the environment, since organic solvents that are environmentally unfriendly materials are used in the current art, and the aim of said invention is to develop new nanoscale fluorescent systems and to improve the performance of machines that require such nanoparticles. The present invention can be used in the industry of electroluminescent devices, and for labelling biological molecules.

IPC Classes  ?

• B82B 1/00 - Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• C08J 3/02 - Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
• C08J 3/20 - Compounding polymers with additives, e.g. colouring
• C08L 25/00 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ringCompositions of derivatives of such polymers
• C08L 23/00 - Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bondCompositions of derivatives of such polymers
• C08L 35/00 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereofCompositions of derivatives of such polymers
• C08L 83/00 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon onlyCompositions of derivatives of such polymers
• C09K 11/02 - Use of particular materials as binders, particle coatings or suspension media therefor
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• C09K 11/07 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
• A61K 49/00 - Preparations for testing in vivo
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
• A61K 9/51 - Nanocapsules
• G01N 21/64 - FluorescencePhosphorescence
• G01N 33/533 - Production of labelled immunochemicals with fluorescent label

Abstract

According to the present invention, there are several methods for detecting microcystins, which have a limited capacity to adequately identify and monitor in real time structural variants of said toxins. The present inventive method and inventive device enable the detection, identification, quantification and real-time monitoring of microcystins in aqueous media. The inventive method is based on the fact that the influx and interaction of microcystins in the aqueous opening of a protein nanopore, formed by alpha-toxin incorporated into a resistive matrix, induces discretized events in the ion current that flows through the nanopore. The temporal series of said events is representative of and correlated with the microcystin structural variant present in the solution contained in one of the conductive reservoirs. The segmental statistical analysis of the temporal series, combining the method of least squares and genetic optimization algorithm, allows real-time discrimination of the microcystin variants. The inventive device consists basically of a nanopore incorporated into a lipid bilayer that separates two conductive reservoirs, wherein the microcystins are placed in one of the reservoirs.

IPC Classes  ?

• G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variablesInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
• G01N 27/404 - Cells with anode, cathode and cell electrolyte on the same side of a permeable membrane which separates them from the sample fluid
• G01N 33/18 - Water
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers

Abstract

A thrust-stabilised magnetic levitation ultracentrifuge comprises a magnetic levitation homopolar motor formed by a lower cylindrical magnet (1) that carries two parallel bismuth or graphite cylinders (2) with a rotor (3) located in a vacuum therebetween and comprising a lower electrically insulating disk (4) and two parallel cylindrical magnets (5 and 6) made of NbFeB (neodymium, iron and boron) or AlNiCo (aluminium, nickel and cobalt) interconnected by a hollow steel cylinder (7), the inside of which is in communication with the outside through a central vertical channel (8) located inside the upper magnet, and through which the sample to be centrifuged is injected and withdrawn, rotation being caused by the influence of the magnetic field on the electric current (9) that flows through the mercury or gallium (10) that fills the inside of the upper metal recipient (11) up to the positive pole (12) attached to the metal frame (13). The present invention is applicable in the fields of centrifuges and ultracentrifuges for industrial or domestic use.

IPC Classes  ?

• F16C 39/06 - Relieving load on bearings using magnetic means
• F16C 32/04 - Bearings not otherwise provided for using magnetic or electric supporting means

Abstract

A rotary evaporator with magnetic heating can be used in the fields of chemical heating, desalination and biodiesel synthesis and in the environmental remediation industries. The invention relates to a rotary evaporator that comprises a cylindrical rotor (1) that is made of metal (copper, aluminium, brass, stainless steel, galvanised steel, zinc, tungsten) and contains cavities in the surface (2) thereof. The cylindrical rotor (1) rotates together with a shaft (3) supported on bearings (4) of the tops, which bearings are fitted (5) by means of screws (6) and nuts (7) into the frame (stator) (5) in which they are located; or the rotary evaporator comprises permanent magnets (8) (ferrite, neodymium, samarium-cobalt, aluminium-nickel-cobalt magnets) attached to the outside of same or a copper wire spool (9) supplied with an oscillating current within a radiofrequency range from 1 KHz to 800 KHz (10). In these arrangements, the perforated rotor (1) ejects hot water and steam under pressure out of the rotary evaporator, through a valved duct (11). It thus produces a greater quantity of steam and heat by unit of time, because of the heating caused through magnetic induction by the magnets or copper wire spools located on the rotor, during the rotation of the rotor.

IPC Classes  ?

• H05B 6/02 - Induction heating
• F24J 3/00 - Other production or use of heat, not derived from combustion (use of solar heat F24J 2/00)
• F22B 3/06 - Other methods of steam generationSteam boilers not provided for in other groups of this subclass by transformation of mechanical, e.g. kinetic, energy into heat energy

Abstract

The present invention can be used as an antitumour drug for testosterone-dependent tumours, in particular prostate cancer. The invention relates to a molecular compound composed of testosterone molecules chemically bonded to a chemotherapeutic radioactive iodine atom (I-124, 125 or 131) aimed at combating testosterone-dependent tumours, in particular prostate cancer, eliminating the undesirable collateral effect of known chemotherapeutic compounds, which is the destruction of rapid growth cells such as white blood cells. The main contribution of the invention is the use of testosterone as the chemotherapeutic agent carrier. In particular, a testosterone molecule chemically bonded to a radioactive iodine atom is used, which can be iodine-125, 125 or 131.

IPC Classes  ?

• C07J 1/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, not substituted in position 17 beta by a carbon atom, e.g. oestrane, androstane
• A61K 51/04 - Organic compounds
• A61K 101/02 - Halogens
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention provides fluorescent nanoparticle composites themselves, the process of preparing such composites, to systems for rapid diagnosis (as “kits”) containing such composites, and to the use of such composites. In a preferential embodiment, the composites of the present invention have an affinity for biological molecules, such as DNA. The present invention also comprises the preparation of probes containing biological material, upon which are added fluorescent nanoparticle composites, making viable a rapid and economic biological diagnosis of, for example, diseases and genetic traits, notably in the medical and veterinarian fields. There is yet the fact that the absorption of radiation in the ultraviolet and visible regions, with the emission of light in the near ultraviolet and visible range, including in the colors of deep blue and/or green, provides advantageous use of its fluorescent properties in photovoltaic or electroluminescent devices, such as organic LEDs, or for the increase in luminous gain of fluorescent lamps, which represents another characteristic of the invention.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• A21D 6/00 - Other treatment of flour or dough before baking, e.g. cooling, irradiating or heating
• A23C 3/00 - Preservation of milk or milk preparations
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
• G01N 33/533 - Production of labelled immunochemicals with fluorescent label

Abstract

The present invention relates to the synthesis and structural identification of new thiazolidine and imidazolidine compounds with trypanocidal activity, and to the therapeutic use thereof as drugs against Chagas disease.

IPC Classes  ?

• A61K 31/475 - QuinolinesIsoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
• A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
• A61K 31/426 - 1,3-Thiazoles
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
• A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• C07D 277/34 - Oxygen atoms
• C07D 417/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 233/96 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
• A61P 33/02 - Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Abstract

The present invention relates to a device formed by printing a substance that is sensitive to exposure to ultraviolet radiation on any substrate, which acts as functional ink and then as a dosimeter for ultraviolet radiation (UV-A, UV-B or UV-C). A conventional printer is used for printing, but with the UV-radiation-sensitive substance instead of ink, on paper, adhesive labels, polymer, fabric, or other substrate which can immobilize the active substance used. After being printed with the active substance, the substrate, cut into a specific shape, is then used as a UV dosimeter, for personal or environmental monitoring, if the substance used as ink is luminescent and the intensity of the emitted luminescence decreases appropriately according to the UV-radiation dose received, such as the lanthanide complexes, or other substance that results in a compound that is sensitive to UV radiation, or any type of luminescent substance which changes with UV radiation, and is dispersed in a solvent enabling it to be used as an ink substitute in the printer, or pure, or also when the ink changes colour according to the UV-radiation dose received. The printed substrate may have a specified area that is protected from radiation exposure to be used as reference to evaluate the dose of UV radiation. In the case of a luminescent substance, the accumulated dose may be read by placing the substrate, following exposure, into a reader which measures luminescence intensity at a wavelength range corresponding to the characteristic emission of the substance used. The accumulated dose may be measured by comparing luminescence from the exposed portion of the substrate to that of the non-exposed portion. The relative measurement can be converted into dose. In the case of a substance which changes colour according to the UV-radiation dose received, the reading can be visual, qualitative by comparing the colour of the exposed area to the non-exposed area, or quantitative by placing the substrate into a reflectance or absorption reader for the corresponding spectral region, following calibration using values which correspond to each accumulated-dose range. Besides allowing the received and accumulated radiation dose to be determined, the same system may, optionally, enable visual monitoring for detecting a permitted UV-radiation-dose limit, for use in controlling industrial processes or preventing individual overexposure.

IPC Classes  ?

• G01J 1/58 - Photometry, e.g. photographic exposure meter using luminescence generated by light
• G01J 1/38 - Photometry, e.g. photographic exposure meter using wholly visual means

Abstract

The present invention can be used as an antitumoral medicament for testosterone-dependent tumours, in particular prostate cancer. The invention is a molecular compound formed by testosterone molecules chemically linked to molecules of a chemotherapeutic drug by means of intercalating alkyl molecules with three or more carbons, and aims at combating testosterone-dependent tumours, in particular prostate cancer, eliminating the undesirable effect of tumour resistance to the efflux of known chemotherapeutic compounds. The main contribution of the invention is the use of testosterone as a carrier for the chemotherapeutic drug. In particular, a testosterone molecule chemically linked to a 9-aminoacridine molecule by means of an intercalating alkyl molecule with three or more carbons is used, as an example of one of the compounds that can be produced according to the invention described.

IPC Classes  ?

• C07J 7/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 beta by a chain of two carbon atoms
• A61K 31/568 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstane, testosterone
• A61P 35/00 - Antineoplastic agents
• C07D 219/12 - Aminoalkyl-amino radicals attached in position 9
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines

Abstract

The present invention has applications in the fields of medicine, pharmaceutics and biological tissue engineering. The invention relates to the development of a bioactive composite for bone repair with a polymer matrix composed of a polysaccharide, and strengthened with calcium derivatives, such as calcium hydroxide, hydroxylapatite, or calcium phosphate, in order to produce bioactive composites specific to bone tissue. The strengthening material is used at different concentrations relative to the matrix in order to produce mouldable composites machined into fracture-resistant screws, pins and plates with various elastic deformation values suitable for specific uses in bone fixation, bone repair, bone induction and bone conduction for the treatment of lesions of bone tissue accompanied by loss of substance, including critical defects.

IPC Classes  ?

• A61L 27/48 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
• A61L 27/46 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
• A61L 27/20 - Polysaccharides

Abstract

A double-beveled needle for the lysis of microvaricose veins and telangiectasias comprises a double-beveled end and a coupling end. When the needle touches the skin, on the vessel to be destroyed, it causes the immediate and selective lysis of the vessel. Unlike conventional treatments that cause chemical inflammation, hardening and subsequent absorption of the vessel, the destruction ensured by this needle does not require these stages in the treatment, immediately destroying the vessel and avoiding spots, burns and hardening in the treated zone. The needle is easy to use, of low cost and accessible even to beginners in this discipline.

IPC Classes  ?

• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles

Abstract

A gas storage system by compression and adsorption is useful in the field of fuels, in particular for storing and transporting gas. The present invention optimises gas storage operations by utilizing the energy obtained by the combination of the effects of simultaneous adsorption and desorption in a new gas storage system by compression and adsorption comprising two concentric reservoirs containing identical charges of activated carbon. The present gas charging and discharging system does not use auxiliary means, such as external sources, and has an increased thermal stability in a reasonable pressure range, i.e. it is more efficient and makes new storage cycles without external processing possible, reducing operating costs in comparison with the prior art.

IPC Classes  ?

• F17C 11/00 - Use of gas-solvents or gas-sorbents in vessels

Abstract

The present invention relates to a semiconducting nanodevice comprising a heterojunction made of a conducting polymer (PANI) and zinc oxide (ZnO). Electronic devices having specific electric characteristics can be obtained by controlling the doping properties, the degree of oxidation of the conducting polymer and the physical dimensions of the zinc oxide films. This technology can be used to produce a semiconducting p-n junction having with rectifier diode characteristics, as well as a varistor-type device with controlled breakdown voltages, and having unprecedented features for which protection is sought. The device comprises a metallic film made of either gold or aluminium, a thin polyaniline film of various thicknesses and sizes, a zinc oxide film of various thickness and sizes, and finally metallic contacts made of aluminium or gold as depicted in figure 1. The electric characteristics of these new devices are improved over those of commercially available devices, since they constitute organic hybrid devices which are cheaper and easier to produce. Another important aspect is the possibility to control the breakdown voltage of the device by varying the degree of doping and the thickness of the active components.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof

Abstract

The present invention relates to an antineoplastic testosterone molecular complex comprising a testosterone molecular chain (1), an antineoplastic drug and a molecular bridge or molecule. The present compound is characterised in that it comprises a testosterone molecule (1) chemically bonded to a commercially available antineoplastic drug, such as daunorubicin or doxorubicin (2), cisplatin (3), carboplatin (4) or cisplatin-berenil (5), by a molecular bridge such as carbamate (6) or by an N',N-disuccinimidyl-carbonate molecule (7). The molecular complex "guides" the anti-cancer drug directly to the tumour, enabling the drug to have a selective effect on the prostate, and thus preventing effects on healthy tissues, since this type of cancer requires large amounts of testosterone to develop.

IPC Classes  ?

• C07J 7/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 beta by a chain of two carbon atoms
• A61K 31/568 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstane, testosterone
• A61P 35/04 - Antineoplastic agents specific for metastasis
• A61P 35/00 - Antineoplastic agents
• A61K 31/282 - Platinum compounds
• A61K 31/28 - Compounds containing heavy metals
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin

Abstract

The present invention relates to the production of luminescent ammunition and detection of gunshot residues and the associated manufacturing process. It uses the incorporation of luminescent markers in the primer or propellant (gunpowder) of any kind of firearms ammunition of any caliber. This makes it possible both to mark ammunition and to detect gunshot residues using the luminescence emitted, including residues left by lead-free ammunition. The process is based on the luminescent properties of the markers added, thereby overcoming some of the limitations of the analytical techniques currently in use.

IPC Classes  ?

• C06B 23/00 - Compositions characterised by non-explosive or non-thermic constituents
• C06C 7/00 - Non-electric detonatorsBlasting capsPrimers
• C09K 11/07 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
• F42B 5/16 - Cartridges, i.e. cases with propellant charge and missile characterised by composition or physical dimensions or form of propellant charge or powder

Abstract

The present invention provides fluorescent nanoparticle composites themselves, the process of preparing such composites, to systems for rapid diagnosis (as "kits") containing such composites, and to the use of such composites. In a preferential embodiment, the composites of the present invention have an affinity for biological molecules, such as DNA. The present invention also comprises the preparation of probes containing biological material, upon which are added fluorescent nanoparticle composites, making viable a rapid and economic biological diagnosis of, for example, diseases and genetic traits, notably in the medical and veterinarian fields. There is yet the fact that the absorption of radiation in the ultraviolet and visible regions, with the emission of light in the near ultraviolet and visible range, including in the colors of deep blue and/or green, provides advantageous use of its fluorescent properties in photovoltaic or electroluminescent devices, such as organic LEDs, or for the increase in luminous gain of fluorescent lamps, which represents another characteristic of the invention.

IPC Classes  ?

• B82B 1/00 - Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• G01N 33/533 - Production of labelled immunochemicals with fluorescent label
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

Abstract

The present invention is related to a new series of chemical compounds, namely 3-benzyl-imidazolidine-2,4-dione substituted in the position 2 and/or 6 of benzyl ring by halogens as presented to the molecule named LPSF-PT-31, GIRSUPAN and its therapeutic use as drug with analgesic, sedative and adjuvant of anesthetics activities. The invention is also related to a process for production of said compounds as well as pharmaceutical compositions comprising them.

IPC Classes  ?

• C07D 233/72 - Two oxygen atoms, e.g. hydantoin

Abstract

The present invention discloses new acridine derivatives according to general formula (I) below, useful as antitumor agents, methods for its preparation as well as pharmaceutical compositions containing the same are also disclosed: (Formula I).

IPC Classes  ?

• C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines