According to a first aspect of the present disclosure, there is provided a turning device featuring a guide forming a path, and a set of at least three conveying platforms arranged below and successively along the path. The turning device further includes a first and a third conveying platform having a first rotating direction and a second conveying platform having a direction opposite to the first rotating direction.
B65G 35/06 - Mechanical conveyors not otherwise provided for comprising a load-carrier moving along a path, e.g. a closed path, and adapted to be engaged by any one of a series of traction elements spaced along the path
B65G 47/74 - Feeding, transfer, or discharging devices of particular kinds or types
2.
SYSTEMS AND METHODS FOR RAPID MICROBIAL IDENTIFICATION
Mass Spectrometry has been widely used to identify microbes present in a sample. However, rapid analysis (e.g. 1-5 minutes) of spectral data to identify microbes has proven to be very challenging due to the high level of processing required and complexity associated with identification from a large pool of candidate microbes. Disclosed herein are methods and systems for rapidly identifying microbes present in a sample through the application of conditional likelihoods that certain proteoforms are particularly indicative of a candidate microbe.
A receptacle holder having a base body, a first perimeter wall which at least partially protrudes from the base body, and a plurality of resilient elements, which are distributed about a first axis of the receptacle holder and are detachably connected with the first perimeter wall, and wherein each resilient element comprises a first end portion and a second end portion, and wherein each second end portion rests hooked over an edge of a portion of the first perimeter wall, and wherein the receptacle holder is configured to allow sliding of each second end portion in a direction perpendicular to the first axis.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A novel waste bin carrier (100) is proposed for carrying at least one waste bin (200). The waste bin carrier (100) includes a frame (110) having a base (130) for receiving thereon one waste bin (200) or more. The waste bin carrier (100) also has a locking mechanism (120) movably attached to the frame (110) for releasably securing at least one waste bin (200) to the waste bin carrier (100). The locking mechanism (120) has a pusher guide (121) that extends in a first horizontal Cartesian dimension (X) for lateral engagement with the waste bin (200). The locking mechanism also has at least one articulated arm (122) that connects the pusher guide (121) to the frame (110) of the waste bin carrier (100) for allowing movement of the pusher guide (121) in respect to the frame (110) between the deployed state and the released state.
B62B 3/04 - Hand carts having more than one axis carrying transport wheelsSteering devices thereforEquipment therefor involving means for grappling or securing in place objects to be carriedLoad handling equipment
B62B 3/10 - Hand carts having more than one axis carrying transport wheelsSteering devices thereforEquipment therefor characterised by supports specially adapted to objects of definite shape
6.
Mass spectrometric methods and kits to identify a microorganism
The present invention includes a novel method and system for identification of microorganisms in samples that proteins and other biological material from non-microorganism sources (e.g., proteins of mammalian origin) that can interfere with identification of the microorganisms. The methods and systems described herein include use of a single-use chromatography medium to purify intact proteins prior to mass spectrometry analysis. The chromatography medium and the methods described herein can rapidly and efficiently remove of a substantial portion of interfering biological material (e.g., mammalian proteins) from a crude cell lysate while preserving high signal strength and removing enough of the interfering protein(s) to allow for identification of the microorganism(s) by mass spectrometry analysis.
A pipette comprising a cylinder with a piston movable inside the cylinder for aspiring and dispensing liquid, and a handle portion for gripping the pipette, wherein the pipette further comprises an imaging device element for obtaining images that assist the use of the pipette.
A method of multiplexing the operation of a sample preparation and analysis system is disclosed. The system includes a sample preparation system capable of preparing a first sample in accordance with a first assay that is selected from a database containing a plurality of unique assays and preparing a second sample in accordance with a second, different assay. The method includes separately transporting the first and second prepared samples to an analysis station having first and second separation channels and an analyzer comprising a mass spectrometer. The method further includes simultaneously analyzing the first prepared sample with the analyzer in accordance with the first selected assay and separating the second prepared sample with the second separation channel in accordance with the second selected assay.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
H01J 49/00 - Particle spectrometers or separator tubes
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A gripper comprising an actuator and two fingers mounted parallel at a distance from each other on the actuator for movement perpendicularly to a longitudinal axis of the fingers, the fingers having a longitudinal body attached at one end to the actuator. The fingers having two longitudinal claws at the end opposite to the end attached to the actuator, the claws being spaced apart so that there is an elongated gap between the claws. At least one of the fingers having a groove for accommodating an optical fiber which extends partially into the elongated gap.
An apparatus for pretreatment of a desired sample in a discrete fluid analyzing instrument includes a frame rotatably mounted on or within the discrete fluid analyzing instrument with a column for immobilizing at least one substance or analyte from the sample. The substance or analyte is reversibly immobilized. A first fluid transport line is provided for aspirating the sample into the column and for ejecting the substance or analyte eluted from the column. A pump is provided for pumping the sample through the column with a second fluid transport line connecting the pump to the column. A member is providing to supply the eluted substance or analyte to the discrete fluid analyzing instrument for measurement of at least one property of the substance or analyte. A device is provided for simultaneously or consecutively directing any non-pretreated sample or any subsample directly to the discrete fluid analyzing instrument.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
An apparatus for pretreatment of a sample of whole blood in a discrete fluid analyzing instrument comprises automated means for handling and analyzing the sample and means for performing a pretreatment step on the sample or a sub-sample of the sample. The means for pretreatment are used for immobilizing at least one substance or analyte from the sample or sub-sample wherein the substance or analyte is reversibly immobilized. Usually, the apparatus further comprises means for eluting the substance or analyte from the capture means prior to analysis.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
A sample vessel (1, 11) for transferring and analyzing a sample with analyzer instrument, which sample vessel comprises an elongated vessel body (2, 12) for containing the sample and a hinged cap (3, 13) connected in top end area of the vessel body, and the cross-section of the vessel body (2, 12) on a transversal plane in relation to the lengthwise center axis of the vessel body the inner surface of the vessel body is rotationally asymmetrical in relation to the lengthwise center axis, wherein the sample vessel (1, 11) comprises a surface (5, 15) extending upwards from the vessel body, which surface partially surrounds the edge of the cap (3, 13), when the cap is in closed position.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
B65D 47/00 - Closures with filling and discharging, or with discharging, devices
B65D 41/18 - Snap-on caps or cap-like covers non-metallic, e.g. made of paper or plastics
B65D 47/08 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages having articulated or hinged closures
B65D 47/40 - Closures with filling and discharging, or with discharging, devices with drip catchers or drip-preventing means
16.
Sample vessel rack, method for locking sample vessels in a sample vessel rack and sample vessel rack system
A sample vessel rack (1), which comprises a frame (2) with a plurality of openings (3) in the upper surface of the frame for sample vessels (9), and a locking plate member (5) movable in a plane parallel to the upper surface of the frame (2) of the rack from a releasing position to a locking position and back, wherein the removal of the sample vessels (9) from the rack is prevented when the locking plate member is in the locking position, the openings (3) of the upper surface of the frame (2) comprises slots (12) formed on their side, and in the locking position a part of the locking plate member (5) sets itself in the area of the slots. The invention also relates to such a method and a sample vessel rack system.
A method and apparatus for opening a reaction vessel having a body forming a volume for liquid, and a lid. In the method at least one reaction vessel is placed on a transport vehicle and the reaction vessel is positioned on the vehicle so that the vessel's rotation about its own axis is prevented. Then, the at least one reaction vessel is transferred on the vehicle and a guide rod, attached to the lid that is attached by a hinge to the reaction vessel, is pushed by the movement of the vehicle against a guide surface that forces the lid to turn on the hinge so that the lid is at least partially opened.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A pipette comprising a cylinder with a piston movable inside the cylinder for aspiring and dispensing liquid, and a handle portion for gripping the pipette, wherein the pipette further comprises an imaging device element for obtaining images that assist the use of the pipette.
A pipette is described which includes a piston for aspirating liquid into and dispensing out of a container in the pipette. The pipette is provided with at least one tracking element which is able to count the magnitude of some variable or variables relating to the amount of use of the pipette, at least one operating device for creating a limit magnitude for each variable, and for giving information when the limit value is exceeded. Thus, the user may, for instance, be warned when he may be exposed to high workload stress possibly causing injuries.
An electronic pipette comprising a piston actuated in a cylinder by a motor, a control system for carrying out pipette operations, and a user interface for operating the pipette, which user interface comprises a display, wherein the main menu of the user interface comprises a user defined shortcut to a specific pipetting application.
Described are extraction columns and systems that include extraction columns. The extraction column includes a column body that has a reservoir portion, an extraction media portion, and a collar portion. The reservoir portion includes an inlet and a reservoir. The extraction media portion includes an elongated sleeve having an inner surface defining a cavity. The extraction media portion has an inlet end in fluid communication with the reservoir and an outlet end. An extraction medium is disposed in the cavity of the elongated sleeve. The collar portion extends axially in a common direction with the elongated sleeve. The collar portion has a terminal end which is spaced apart from the outlet end of the elongated sleeve and which extends axially at least to a plane defined by the outlet end of the elongated sleeve.
G01N 30/00 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
A method for controlling an electronic pipette, which pipette comprises a piston actuated in a cylinder by a motor, which motor is controlled with a control system, which control system is controlled through a user interface for operating the pipette, wherein actual backlash affecting the movement of the piston of the electronic pipette is measured with a system located in the pipette, the measured backlash value is forwarded to the control system of the electronic pipette, and the movement of the piston is adjusted by the control system based on the measured backlash value.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
G06F 19/24 - for machine learning, data mining or biostatistics, e.g. pattern finding, knowledge discovery, rule extraction, correlation, clustering or classification
G06G 7/58 - Analogue computers for specific processes, systems, or devices, e.g. simulators for chemical processes
A novel solution is proposed for processing a test tube transported on a test tube carrier by a conveyor so that spilling of the liquid in the test tube is reduced or even prevented, particularly an arrangement for sequencing and guiding travel of test tube carriers transported on at least one conveyor. The arrangement includes at least one rotatable deviator positioned to intersect the at least one conveyor. The deviator includes a horizontal deviator plate including at least one grip for receiving a test tube carrier. One contact surface is positioned vertically at a distance from the deviator plate and aligned with the grip. The contact surface is formed to contact the test tube carrier at a distance from the contact level of the grip and the carrier.
B65G 47/84 - Star-shaped wheels or devices having endless travelling belts or chains, the wheels or devices being equipped with article-engaging elements
A sample preparation and analysis system. The system includes a sample preparation system and a sample analysis system. The sample preparation system prepares samples in accordance with an assay that is selected from a database containing a plurality of unique assays. The sample analysis system includes an analyzer that is dynamically reconfigurable based on the selected assay so as to analyze the prepared sample in accordance with that selected assay. A data communication link communicates data from the sample preparation system to the sample analysis system to reconfigure the analyzer in accordance with the selected assay.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
H01J 49/26 - Mass spectrometers or separator tubes
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
H01J 49/00 - Particle spectrometers or separator tubes
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
The present invention relates to a device for thermal cycling of biological samples, a heat sink used in such a device and a method. The heat sink comprises a base plate designed to fit in a good thermal contact against a generally planar thermoelectric element included in the device, and a plurality of heat transfer elements projecting away from the base plate. According to the invention, the heat transfer elements of the heat sink and arranged in a non-parallel configuration with respect to each other for keeping the temperature of the base plate of the heat sink spatially uniform during thermal cycling.
A sample preparation and analysis system. The system includes a housing with a sample preparation station and a sample analysis station positioned within the housing. The sample analysis station is spaced away from the sample preparation station. A transport assembly is configured to move at least one sample within the housing and between the sample preparation station and the sample analysis station.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
H01J 49/00 - Particle spectrometers or separator tubes
A pipette is described which includes a piston for aspirating liquid into and dispensing out of a container in the pipette. The pipette is provided with at least one tracking element which is able to count the magnitude of some variable or variables relating to the amount of use of the pipette, at least one operating device for creating a limit magnitude for each variable, and for giving information when the limit value is exceeded. Thus, the user may, for instance, be warned when he may be exposed to high workload stress possibly causing injuries.
An electronic pipette comprising a piston actuated in a cylinder by a motor, a control system for carrying out pipette operations, and a user interface for operating the pipette, which user interface comprises a display, wherein the main menu of the user interface comprises a user defined shortcut to a specific pipetting application.
The present invention concerns a pipette comprising a mechanism with which the stroke length of a piston can be changed by rotating the piston rod. The pipette comprises a locking mechanism which prevents the rotation of the piston rod when the piston has been pushed a certain distance downwards from its upper position, but does not prevent the rotation when the piston is in its upper position.
A reagent bottle includes an outer cap and an inner closing cap. The inner closing cap has a recess for gripping the cap. In addition, a system for handling closures is provided wherein a method removes a closing cap from a reagent bottle and a related gripper.
The invention concerns a method for processing magnetic particles, which selectively interact with a substance present in a liquid medium. The particles are collected with a probe (2) comprising a hollow shield (4) and a probe magnet (3) moveable up and down. The lower end of the probe with the collected particles is placed on a release location (7) of a plate (6), below which release location there is a release magnet (8). The surface of the release location is dry or has a liquid film or a drop on it. In accordance with the invention, very high concentration ratios can be achieved.
The invention relates to liquid dispensing and concerns a pipette comprising at least one aspiration channel with a piston. At the lower end of the aspiration channel there is an extension channel (3) and at its end a pipette tip mounting piece (4) onto which a pipette tip (5) is attached. On the pipette tip mounting piece there is a surrounding groove (17) and in the groove a sealing ring (18). The width of the groove in the axial direction is at least 1.1 times the thickness of the sealing ring in the axial direction. When the mounting piece is pushed into the pipette tip, the inner wall of the tip can move the sealing ring upwards in the groove. The construction can provide a reliable sealing despite of inherent dimension differences between different tips and mounting pieces.
A sample preparation and analysis system. The system 10 includes a sample preparation system 12 and a sample analysis system 14. The sample preparation system 12 prepares samples in accordance with an assay that is selected from a database containing a plurality of unique assays. The sample analysis system 14 includes an analyzer 110 that is dynamically reconfigurable based on the selected assay so as to analyze the prepared sample in accordance with that selected assay. A data communication link 27 communicates data from the sample preparation system 12 to the sample analysis system 14 to reconfigure the analyzer 110 in accordance with the selected assay.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
H01J 49/00 - Particle spectrometers or separator tubes
A sample preparation and analysis system (10). The system (10) includes a housing (16) with a sample preparation station (12) and a sample analysis station (14) positioned within the housing (16). The sample analysis station (14) is spaced away from the sample preparation station (12). A transport assembly (50) is configured to move at least one sample within the housing (16) and between the sample preparation station (12) and the sample analysis station (14).
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
A method and apparatus for transporting single and multiple reaction vessels. At least one reaction vessel is provided and at least one tray includes at least two seats for the at least one reaction vessel, and at least one gripper. One of the reaction vessel or the tray is engaged with the gripper at a first position. The gripped element is transported to a second position wherein the gripper is released. A gripping collar is provided both on the reaction vessel and the tray for the gripper to engage. At one transport stage one of the reaction vessel or the tray is engaged with the gripper at a first position by pushing the gripper from above to engage with the gripping collar and in a second stage the transported element is disengaged from the gripper by moving the gripper sideways in relation to the center axis of the gripping collar.
A method and apparatus for opening a reaction vessel having a body forming a volume for liquid, and a lid. In the method at least one reaction vessel is placed on a transport vehicle and the reaction vessel is positioned on the vehicle so that the vessel's rotation about its own axis is prevented. Then, the at least one reaction vessel is transferred on the vehicle and a guide rod, attached to the lid that is attached by a hinge to the reaction vessel, is pushed by the movement of the vehicle against a guide surface that forces the lid to turn on the hinge so that the lid is at least partially opened.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A method for pretreatment of a sample of whole blood in a discrete fluid analyzing instrument comprises automated means for handling and analyzing the sample and means for performing a pretreatment step on the sample or a sub-sample of the sample. The means for pretreatment are used for immobilizing at least one substance or analyte from the sample or sub-sample wherein the substance or analyte is reversibly immobilized. Usually, the apparatus further comprises means for eluting the substance or analyte from the capture means prior to analysis.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Automatic analyzers, in which the liquids to be analyzed are in so-called reaction vessels, simultaneously acting as optically high-quality cuvettes (10), are used in laboratories for analyzing various liquids. Further described is a handling package for cuvettes (10). A removable bonding strip (100) is fastened on the rows of cuvettes (10), the strip (100) binding the rows of cuvettes (10) during transport, and being easily removable when the cuvettes (10) are loaded into the instrument. The cuvettes (10) are loaded into the instrument by supporting the package in its place from the brackets (24) located in the ends of the cuvettes (10), so that the strip (100) can be pulled off the supported package of cuvettes (10).
B65D 85/00 - Containers, packaging elements or packages, specially adapted for particular articles or materials
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A handle pipette including at least one cylinder with an upper end and a lower end, said cylinder having a movable piston, an elongate handle (1), by which the pipette can be manually gripped, said handle having an upper part, and in the upper part of the handle, a sideways extending finger support (7), which finger support (7) is at least partly flexible and/or it can be shaped by the user.
A support pipette including at least one cylinder with an upper end and a lower end, each cylinder having a movable piston, and an elongate handle (1) with an upper part and a lower part, at which handle the pipette can be manually gripped, wherein the lower part (13.1; 13.2; 13.3) of the handle (1) includes a sideways protruding lower support (10.1; 10.2; 10.3; 10.4; 10.5).
A chemical analyzer, a method for sample-based analysis, a device for handling cuvette assemblies including a rotatable incubator with at least one curved opening for receiving a new cuvette assembly, an analyzer arranged around the incubator for analyzing contents of the new cuvette assembly, and a loading device adapted to carry the new cuvette assembly while initially being aligned in a straight manner before being loaded. The loading device includes a feed funnel having a first end for receiving the new cuvette assembly initially aligned in the straight manner into the feed funnel, and a second end for feeding the new cuvette assembly into the at least one curved opening, the second end having a curvature which corresponds to the curvature of the curved opening, the second end for bending the initially straight new cuvette assembly and fitting the new cuvette assembly into the at least one curved opening.
A cuvette (10) for an automatic analyzing apparatus according to the invention includes at least two positions (20), for each position pair one separating wall (22) connecting the positions (20), and brackets (24), which are at the outermost positions (20) and which guide the cuvette (10) into a curved shape. In a handling method of a cuvette (10) according to the invention a cuvette (10) is transported from its brackets (24) to an incubator (30) and bent into a curved shape. In the method the cuvette (10) is then loaded into an opening (34) of the incubator (30), in which opening (34) it remains by its own spring back factor, until the cuvette (10) is removed from the opening (34) after the analysis.
The invention relates to a pipette tip package, which has one pipette tip (1) in an enclosure (2) with a closed bottom end and a top end tightly closed by a lid.
A47F 1/04 - Containers with arrangements for dispensing articles
B65D 85/20 - Containers, packaging elements or packages, specially adapted for particular articles or materials for incompressible or rigid rod-shaped or tubular articles
B65D 21/00 - Nestable, stackable or joinable containersContainers of variable capacity
B65D 81/02 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
B65D 73/00 - Packages comprising articles attached to cards, sheets or webs
The invention concerns a method for detecting the amounts of substances that may disturb chemical analysis performed by an analyzer for clinical chemistry. The presence and concentration of hemoglobin, bilirubin and lipemia are detected by measuring the absorbance or reflectance on at least two, preferably six, different wavelengths over the measured spectrum. The measurements are performed at two wavelengths for each substance, preferably on the absorbance peaks of the specific substance and on the root of the specific peaks. Since the three substances mentioned above each have at least one peak in the spectrum, the measurement is done on three peaks and three root positions respectively when three substances have to be measured.
The invention concerns a thermal cycler and a microtiter plate. The cycler comprises a sample holder having a first surface and a surface and means for automated, controlled heating and cooling of the sample holder. The first surface of the sample holder is designed to hold a plurality of samples arrayed in a grid having a predefined pitch. The number of samples in one dimension is an exact match of the SBS plate standards for that sample pitch and in another dimension corresponds to a fraction of the number of samples in a second dimension of an SBS microtiter standard plate. According to the invention, the sample holder is shaped such that the area of the second surface is larger than the area of the first surface. By means of the invention, the thermal ramping speeds of the cycler can be significantly increased.
The invention concerns a v-bottomed sample plate, a frame for sample plates and a kit and method for processing biological samples. The kit comprises a tray assembly and a plurality of sample plates designed to fit into the tray assembly. The tray assembly comprises a frame having a central plate receiving portion having a width and length, whereby said tray assembly is capable of accommodating the sample plates side by side in the plate receiving portion. Each of the sample plates contains a plurality of individual sample wells arranged in a grid, the dimension of the plate in a first direction being at maximum the width of the frame and the dimension of the plate in a second direction being at maximum half of the length of the plate receiving portion of the of the frame, and means for enabling automated handling of the plates. The invention enables more efficient biomedical processing of samples.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
54.
Instruments and method relating to thermal cycling
The invention relates to a device for thermal cycling of biological samples, a heat sink used in such a device and a method. The heat sink comprises a base plate designed to fit in a good thermal contact against a generally planar thermoelectric element included in the device, and a plurality of heat transfer elements projecting away from the base plate. According to the invention the heat transfer elements of the heat sink and arranged in a non-parallel configuration with respect to each other for keeping the temperature of the base plate of the heat sink spatially uniform during thermal cycling.
patents
