Abstract

A nebulizer device (1) has an aerosol generator mounted in a housing (2), and a mouthpiece (3). The device is adapted for delivery of an active agent in an aerosol into the buccal cavity, with droplet size greater than 10µm. Aerosolization is started at or after the end of breath inhalation and is stopped at or before the start of breath inhalation. The flow is via mouthpiece (25) with internal ridges (21) which periodically narrow the flow path volume to so that droplets coalesce in the flow path 25 before the mesh (3)

IPC Classes  ?

• A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
• A61M 15/00 - Inhalators

Abstract

A method of delivering aerosolized surfactant to an infant that includes interfacing an aerosolization device with an airway of an infant and aerosolizing, using the aerosolization device, a volume of surfactant into particles having a mass mean aerodynamic diameter (MMAD) of less than about 3 µm at a rate of at least 0.1 ml/min. The surfactant is aerosolized within about 1 to 8 cm from a patient interface. Aerosol is generated for up to approximately 80% or each inspiration. The method also includes delivering the aerosolized surfactant to the infant's airway.

IPC Classes  ?

• A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
• A61M 15/00 - Inhalators
• A61M 16/00 - Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators Tracheal tubes
• A61M 16/08 - BellowsConnecting tubes

Abstract

An aerosolization system includes a respiration system having an inspiratory limb (650) and an expiratory limb (652). The system includes an aerosol chamber (602) coupled with the inspiratory limb via a fluid channel. The fluid channel is disposed such that the aerosol chamber is isolated from continuous flow passing through the respiratory system. The system includes a patient interface (604) positioned at a first location of the aerosol chamber and an aerosolization device (612) positioned at a second location of the aerosol chamber positioned opposite the first location. The aerosolization device includes a reservoir (632) that receives a volume of liquid medicament for aerosolization by the aerosolization device. The aerosol chamber mixes aerosolized medicament from the aerosolization device with respiratory flow received from the respiration system via the fluid channel.

IPC Classes  ?

• A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
• A61M 16/00 - Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators Tracheal tubes
• A61M 16/08 - BellowsConnecting tubes
• A61M 16/14 - Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase

Abstract

An aerosol delivery system (10) that includes an aerosol generator (16) that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump (24) coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor (36) that emits a signal as the patient breathes. A controller (26) couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.

IPC Classes  ?

• A61M 15/00 - Inhalators
• A61M 16/14 - Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase

Abstract

An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient. The aerosol generator includes a housing with a fluid chamber that fluidly communicates with a housing inlet and a housing outlet. Within the housing, the aerosol generator includes a support plate with an aperture that fluidly communicates with the housing outlet. A vibratable member couples to the support plate across the aperture. A piezoelectric actuator also couples to the support plate, and in operation expands and contracts to vibrate the vibratable member, which aerosolizes a fluid. The aerosol generator receives fluid through a fluid conduit that couples to the housing.

IPC Classes  ?

• A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
• A61M 15/00 - Inhalators
• A61M 15/02 - Inhalators with activated or ionized gasesOzone-inhalators
• B05B 17/00 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
• B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
• B41J 2/025 - Ink jet characterised by the jet generation process generating a continuous ink jet by vibration
• B41J 2/04 - Ink jet characterised by the jet generation process generating single droplets or particles on demand
• B41J 2/165 - Prevention of nozzle clogging, e.g. cleaning, capping or moistening for nozzles

Abstract

An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.

IPC Classes  ?

• A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
• A61M 15/00 - Inhalators
• A61M 16/00 - Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators Tracheal tubes
• A61M 16/04 - Tracheal tubes
• A61M 16/06 - Respiratory or anaesthetic masks
• A61M 16/14 - Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
• A61M 16/16 - Devices to humidify the respiration air