ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Chiu, Wei C.
Dolaty, Amir
Gopinath, Ajay
Abstract
A method includes acquiring, by one or more processing circuits, intravascular data, the intravascular data including a plurality of pressure measurements measured at a location within a blood vessel by an intravascular instrument, and determining, by the one or more processing circuits, a mean transit time parameter based on the plurality of pressure measurements. The mean transit time parameter is indicative of a mean transit time corresponding to a flow rate of blood in the blood vessel.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
A system includes: a receiver configured to receive both (i) a signal received from an aortic pressure sensor, representing a measured aortic blood pressure value of an individual, and (ii) a signal received by a distal sensor, representing a measured parameter in a blood vessel of the individual, the receiver including a display configured to display data that is based on at least the measured aortic blood pressure value and the measured parameter; and a communication interface configured to (i) receive a signal representing the measured aortic blood pressure value from the aortic pressure sensor via a wired connection between the aortic pressure sensor and the communication interface, (ii) provide a signal representing the measured aortic blood pressure value to a monitoring device via a wired connection, and (iii) send a signal representing the measured aortic blood pressure value to the receiver via a wireless connection.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Mahlin, Fredrik
Tiensuu, Stefan
Borg, Niklas
Mattsson, Johan
Grundin, Johan
Hilmersson, Mats
Sundler, Sara
Hacker, Dean
Cerepak, Ryan
Abstract
A method for preparing a sensor wire includes: providing a sensor wire configured for biological pressure measurement and including: an elongated member; and a pressure sensor configured for biological pressure measurement, the pressure sensor being mounted at a distal end portion of the elongated member, wherein a dissolvable hydrophilic material is coated on a surface of the pressure sensor; and submerging the pressure sensor in saline solution, whereby the hydrophilic material dissolves and causes the saline solution to contact the pressure sensor.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Svanerudh, Johan
Abstract
An intravascular data analysis system to assess a blood vessel includes: an interface system configured to receive intravascular pressure data including a plurality of distal pressure (Pd) values measured by an intravascular data collection probe and a plurality of proximal pressure (Pa) values; a display system; one or more memory storage devices includes instructions; and a processor in communication with the interface system, the display system, and the one or more memory storage devices. The processor is configured to execute the instructions to: determine a plurality of Pd/Pa ratios based on the plurality of distal pressure (Pd) values and the plurality of proximal pressure (Pa) values, filter the plurality of Pd/Pa ratios using a filter having a time constant TC in a range of 1% to 50% of a heart cycle length, and control the display system to generate a plot based on the plurality of Pd/Pa ratios.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Veszelei, Eugen
Lundgren, Fredrik
Abstract
In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the perimeters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
A system includes: an aortic pressure sensor configured to measure aortic blood pressure of an individual; a distal sensor configured to measure a parameter in a blood vessel; a receiver configured to receive both (i) a signal representing the measured aortic blood pressure value, and (ii) a signal representing the parameter, the receiver comprising a display configured to display data that is based on at least the measured aortic blood pressure value and the measured parameter; and a communication interface configured to (i) receive a signal representing the measured aortic blood pressure value from the aortic pressure sensor via a wired connection, (ii) provide a signal representing the measured aortic blood pressure value to a monitoring device via a wired connection, and (iii) send a signal representing the measured aortic blood pressure value to the receiver via a wireless connection.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Svanerudh, Johan
Abstract
A method of determining one or more diagnostic metrics to assess a blood vessel using intravascular data includes: sampling a sensor of an intravascular data collection probe disposed in the blood vessel during a pullback of the intravascular data collection probe through the blood vessel to obtain sampled distal pressure (Pd) values; receiving, at an intravascular data processing system, the sampled distal pressure (Pd) values and proximal pressure (Pa) values; determining sets of Pd/Pa ratios, each set including Pd/Pa ratios that are determined through an entirety of one heart cycle; determining minimum Pd/Pa ratios, each of which is a minimum within one of the sets of Pd/Pa ratios over the entirety of the corresponding heart cycle; and controlling a display system to generate a plot of a moving average of the minimum Pd/Pa ratios over time during the pullback.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hilmersson, Mats
Abstract
A sensor guide wire for intravascular measurement of a physiological variable includes: a core wire extending at least partly along a length of the sensor guide wire; a sensor element in a sensor region of the sensor guide wire; a jacket having a jacket wall, the jacket being fixed relative to the core wire; and at least one lead connected to the sensor element. The jacket is tubular and includes a proximal end opening, a distal end opening, and a first set of openings extending through the jacket wall. The first set of openings extending through the jacket wall includes a first opening located above the sensor element, a second opening located at a first lateral side of the sensor element, and a third opening located at a second lateral side of the sensor element, and wherein the first, second, and third openings are elongated in a longitudinal direction of the jacket, and are aligned in a circumferential direction of the jacket.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system includes: a sensor wire comprising an insertable portion configured to be inserted in a blood vessel of a patient's body; a sensor disposed at the insertable portion at a distal end of the sensor wire, wherein the sensor is configured to provide an output indicative of a temperature in the blood vessel of the patient's body, when inserted inside the blood vessel of the patient's body; and a transceiver unit configured to transfer information related to the output of the sensor to an external communication module using a frequency hopping technique. The transceiver unit comprises a housing adapted to be connected to a proximal end of the sensor wire and configured to remain external to the patient's body.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Mahlin, Fredrik
Tiensuu, Stefan
Borg, Niklas
Mattsson, Johan
Grundin, Johan
Hilmersson, Mats
Sundler, Sara
Hacker, Dean
Cerepak, Ryan
Abstract
A pressure sensor configured for biological pressure measurement at a distal end portion of an elongated member comprises a dissolvable hydrophilic material coated on a surface of the pressure sensor. A guide wire for biological pressure measurement may include a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A blood pressure measurement system comprising a pressure sensor guide wire comprising a pressure sensor located in a distal region of the pressure sensor guide wire that is configured to be inserted into a blood vessel of a human body and a transceiver unit communicatively coupled to the pressure sensor guide wire. The transceiver unit comprises a housing adapted to be used external to the human body, a sensor signal adapting circuitry configured to process pressure sensor values generated by the pressure sensor to create processed pressure sensor values, and a first transceiver configured to wirelessly transmit a signal representing the processed pressure sensor values using first, second, and third packets at first, second, and third frequencies.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hilmersson, Mats
Abstract
A sensor guide wire includes a sensor element arranged in a jacket in a sensor region of the sensor guide wire; a core wire extending at least partly along a length of the sensor guide wire; and at least one electrical lead connected to the sensor element. The jacket is tubular and includes proximal and distal end openings, a jacket wall, a first opening arranged in the jacket wall, and a second opening arranged in the jacket wall, the first and second openings being proximate to the sensor element. The core wire is adapted to extend through the jacket via the proximal and distal end openings. At least a portion of the first opening and at least a portion of the second opening are both located in the same cross-section of the sensor guide wire, the cross-section being perpendicular to the longitudinal axis of the sensor guide wire.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Veszelei, Eugen
Lundgren, Fredrik
Abstract
In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the parameters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Thomas, Ralph J.
Matejka, John A.
Ness, Peter J.
Abstract
A guide wire for biological pressure measurement includes: a tube extending along an axial direction of the guide wire, wherein the tube includes a circumferential wall and defines a proximal-end opening and a distal-end opening; and a pressure sensor configured for biological pressure measurement, wherein at least a portion of the pressure sensor is mounted within the tube, and wherein the pressure sensor comprises a pressure sensor transducer. The circumferential wall of the tube includes exactly three openings configured for fluid and gas ingress and egress extending radially therethrough.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A blood pressure measurement system comprises: a pressure sensor guide wire comprising a pressure sensor located in a distal region of the pressure sensor guide wire; a transceiver unit communicatively coupled to the pressure sensor guide wire, the transceiver unit comprising: a housing adapted to be used external to the human body, a sensor signal adapting circuitry configured to process a signal representing a pressure reading sensed by the pressure sensor to create a processed pressure reading, and a first Bluetooth transceiver configured to wirelessly transmit a signal representing the processed pressure reading; and a second Bluetooth transceiver configured to wirelessly receive the signal representing the processed pressure reading transmitted from the first Bluetooth transceiver, wherein the second Bluetooth transceiver is connected with a personal computer that is configured to display a value representing the processed pressure reading.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and two sensors disposed within the insertable portion at a distal end of the sensor wire. The sensors are configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Sundler, Sara
Morrissey, Michael S.
Abstract
A guide wire configured for intravascular insertion includes a core wire having a flattened portion configured to allow the core wire to preferentially bend in at least one plane that passes through a longitudinal axis of the core wire. A distal most end of the flattened portion is spaced from a distal most end of the core wire. The guide wire may further include a sensor element configured to measure a physiological variable in a living body and a coil surrounding a portion of the core wire.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Sundler, Sara
Morrissey, Michael S.
Abstract
A guide wire configured for intravascular insertion includes a core wire having a flattened portion configured to allow the core wire to preferentially bend in at least one plane that passes through a longitudinal axis of the core wire. A distal most end of the flattened portion is spaced from a distal most end of the core wire. The guide wire may further include a sensor element configured to measure a physiological variable in a living body and a coil surrounding a portion of the core wire.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and two sensors disposed within the insertable portion at a distal end of the sensor wire. The sensors are configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Mahlin, Fredrik
Abstract
A sensor guide wire for an intravascular measurement of a physiological variable in a living body, may comprise a proximal tube portion; a distal end portion; and a sensor element configured to measure the physiological variable based on exposure to fluid in the living body. The sensor guide wire may further comprise a mounting structure supporting the sensor element in a freely suspended manner in a lumen within the sensor guide wire and/or a cylindrical-shaped jacket forming an interior space housing the sensor element and extending from a distal end of the proximal tube portion to a proximal end of the distal end portion in which the outer circumferential wall of the jacket includes a plurality of slots located between at least one aperture of the outer circumferential wall and one of the distal and proximal ends of the jacket.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Mahlin, Fredrik
Tiensuu, Stefan
Borg, Niklas
Mattsson, Johan
Grundin, Johan
Hilmersson, Mats
Sundler, Sara
Hacker, Dean
Cerepak, Ryan
Abstract
A guide wire for biological pressure measurement includes a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Mahlin, Fredrik
Tiensuu, Stefan
Borg, Niklas
Mattsson, Johan
Grundin, Johan
Hilmersson, Mats
Abstract
A guide wire for biological pressure measurement includes a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Abstract
A sensor element comprises a sensor section comprising a sensor unit configured to measure a physiological variable or any other signal in a living body and to generate a sensor signal in response to the variable or other signal, and a bond section comprising contact members configured to electrically connect at least one signal transmitting microcable. The bond section is coated with an electrically insulating material and the sensor unit is left uncoated. The sensor element may further comprise an intermediate section between the sensor section and the bond section. The intermediate section includes electric connection lines configured to connect the contact members to the sensor unit. The intermediate section is also coated with the electrically insulating material.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tullberg, Mattias
Dahlberg, Mattias
Abstract
An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Svanerudh, Johan
Abstract
In part, the disclosure relates to computer-based methods, and systems suitable for evaluating a cardiac system using a diagnostic metric such as a pressure value-based ratio. Selection of a subset or portion of a cardiac cycle is avoided in one embodiment to increase reliability and usability of a diagnostic ratio and parameters described herein. In one embodiment, a minimum or a relative extrema of a series of diagnostic metrics plotted on a per cycle basis are used to inform diagnosis of a stenosis or other intravascular event or phenomena.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
30.
Sensor guide wire assembly with button-cell type battery
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tiensuu, Stefan
Abstract
A sensor guide wire assembly having a button-cell type battery includes a transmitter unit configured to be connected to a sensor guide wire that is insertable into a patient to measure a parameter, the transmitter unit being configured to wirelessly transfer data representing the measured parameter to a communication unit. The transmitter unit includes a housing, a printed circuit board holder disposed in the housing, and a printed circuit board disposed in the housing and held by the printed circuit board holder. The printed circuit board includes a plurality of electrical contacts. A slider is slidable from a location outside the housing, the slider including a protrusion extending into an area inside the housing. A space within the housing is configured to hold one or more batteries. The slider is slidable from a first position, at which a micro-switch is not activated, to a second position, at which the micro-switch is activated by the protrusion of the slider, which allows power to be provided to the printed circuit board.
St. Jude Medical Coordination Center BVBA (Belgium)
Inventor
Veszelei, Eugen
Lundgren, Fredrik
Abstract
In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the parameters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Mahlin, Fredrik
Abstract
A sensor guide wire for an intravascular measurement of a physiological variable in a living body, may comprise a proximal tube portion; a distal end portion; and a sensor element configured to measure the physiological variable based on exposure to fluid in the living body. The sensor guide wire may further comprise a mounting structure supporting the sensor element in a freely suspended manner in a lumen within the sensor guide wire and/or a cylindrical-shaped jacket forming an interior space housing the sensor element and extending from a distal end of the proximal tube portion to a proximal end of the distal end portion in which the outer circumferential wall of the jacket includes a plurality of slots located between at least one aperture of the outer circumferential wall and one of the distal and proximal ends of the jacket.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Gustafsson, Pär
Abstract
A sensor guide wire for an intravascular measurement of a physiological variable in a living body may include a sensor element configured to measure the physiological variable based on exposure to fluid in the living body; and a cylindrical-shaped jacket forming an interior space housing the sensor element. The jacket comprises an outer circumferential wall with a circumferential surface extending between distal and proximal longitudinal ends of the jacket. The outer circumferential wall of the jacket does not include any apertures along its circumferential surface so as to prevent fluid from passing through the outer circumferential wall and/or the jacket has a constant cross section along its entire length.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Ranganathan, Sathees
Norlin-Weissenrieder, Anna
Hill, Rolf
Abstract
A sensor guide wire for intravascular measurements of at least one physiological or other variable in a living body, comprising a proximal region, a distal sensor region, and a tip region, and at least one sensor element arranged in said sensor region and configured to measure the variable and to generate a sensor signal in response to the variable. The sensor guide wire further comprises a core wire, with a tip core wire portion, wherein at least part of the tip core wire portion comprises a shape memory material, and the composition of the shape memory material is such that the transformation temperature of the shape memory material is above the body temperature of the living body.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Gustafsson, Pär
Abstract
A sensor guide wire for an intravascular measurement of a physiological variable in a living body may include a sensor element configured to measure the physiological variable based on exposure to fluid in the living body; and a cylindrical-shaped jacket forming an interior space housing the sensor element. The jacket comprises an outer circumferential wall with a circumferential surface extending between distal and proximal longitudinal ends of the jacket. The outer circumferential wall of the jacket does not include any apertures along its circumferential surface so as to prevent fluid from passing through the outer circumferential wall and/or the jacket has a constant cross section along its entire length.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tullberg, Mattias
Dahlberg, Mattias
Abstract
An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tullberg, Mattias
Dahlberg, Mattias
Abstract
An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Ranganathan, Sathees
Norlin-Weissenrieder, Anna
Hill, Rolf
Abstract
A sensor guide wire for intravascular measurements of at least one physiological or other variable in a living body, comprising a proximal region, a distal sensor region, and a tip region, and at least one sensor element arranged in said sensor region and configured to measure the variable and to generate a sensor signal in response to the variable. The sensor guide wire further comprises a core wire, with a tip core wire portion, wherein at least part of the tip core wire portion comprises a shape memory material, and the composition of the shape memory material is such that the transformation temperature of the shape memory material is above the body temperature of the living body.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tullberg, Mattias
Dahlberg, Mattias
Abstract
An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the senior wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Abstract
An active noise cancellation device (2) for a medical device includes an active circuit having a first input connection (8), a second input connection (10), and an output connection (12). The second input connection (10) is connected to at least one predetermined reference signal. The active noise cancellation device (2) further includes a low-impedance body connection electrode (4) adapted to be in electrical contact with a bloodstream of a subject, wherein the low-impedance body connection electrode (4) is connected to said first input connection (8), and a feedback branch (14) connecting the output connection (12) with the first input connection (8). The feedback branch (14) comprises a current limiting circuit (18) to limit a current through said feedback branch (14) to be lower than a predetermined current.
H03B 1/00 - GENERATION OF OSCILLATIONS, DIRECTLY OR BY FREQUENCY-CHANGING, BY CIRCUITS EMPLOYING ACTIVE ELEMENTS WHICH OPERATE IN A NON-SWITCHING MANNERGENERATION OF NOISE BY SUCH CIRCUITS Details
H03H 11/12 - Frequency selective two-port networks using amplifiers with feedback
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Abstract
The present invention relates to an extracorporeale interface unit (8), for an intravascular measurement system for measuring at least one physiological, or other, variable in a living body, adapted to generate a sensor signal in response of the variable. The interface unit (8) comprises a sensor interface circuitry (6) adapted to interface a sensor wire configured to be inserted into the living body and provided with one or many sensor element(s) at its distal region. The sensor interface circuitry (6) comprises a measurement unit (9) adapted to generate the measured data of the variable as a sensor signal. The interface unit (8) further comprises a control unit (1) adapted to control and supervise the different functions of the interface unit (8), wherein the different functions are performed by predefined tasks (T1, T2 . . . TN) during consecutive control periods CP having the same time duration.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Ranganathan, Sathees
Norlin-Weissenrieder, Anna
Hill, Rolf
Hansson, Erik
Abstract
A tube for an intravascular medical device has a longitudinal extension along a longitudinal axis. The tube comprises a tube wall having a specified thickness and a plurality of through-going slots, wherein each slot has an essentially elongated shape along a main extension extending along the circumference of the tube. At least two slots are provided in a plane perpendicular to the longitudinal axis such that the main extension of the at least two slots are in the perpendicular plane. The lengths of the slots in the same perpendicular plane P are essentially the same, and the lengths L of the slots in different planes vary along the longitudinal extension of the tube according to a predefined pattern. A sensor guide wire for an intravascular measurement of at least one variable in a living body may comprise such a tube.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Mellin, Lisa
Törne, Karin
Abstract
A sensor guide wire for an intravascular measurement of at least one physiological or other variable in a living body may have a proximal region, a distal sensor region, and a tip region. The sensor guide wire may further comprise a sensor element arranged in the sensor region, and comprising a sensor portion for measuring the variable and to generate a sensor signal in response to the variable. Furthermore, a core wire, having a longitudinal axis A, and comprising at least a tip core wire portion, extends essentially along the tip region of the sensor guide wire. The tip core wire portion may further comprise a distal tip. At least a major part of the tip core wire portion is provided with a polymer layer essentially enclosing the at least major part. The distal tip of the tip core wire portion may further comprise an enlargement.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire, a sensor, and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body. The sensor is disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure or detect a non-physiological parameter when inserted inside the patient. The transceiver unit is adapted to generate a communication signal and to transfer information related to the non-physiological parameter to an external communication module using the communication signal. The communication signal includes sensor values related to the non-physiological parameter. The transceiver unit may comprise a housing adapted to be connected to a proximal end of the sensor wire and configured to remain external to the patient's body.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Abstract
diff) related to the variable at two of the connection points (CP1, CP2, . . . CPn). The present invention further relates to a measurement system (12) comprising said extracorporeale interface unit (8) and a method in said interface unit.
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61B 5/02 - Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hilmersson, Mats
Abstract
The present invention relates to a sensor guide wire (1) for intravascular measurements of at least one variable in a living body, which sensor guide wire (1) has a proximal region (2), a distal sensor region (3) and a tip region (4). The sensor guide wire (1) comprises, a sensor element arranged in said sensor region (3), a tip region core wire (5) having a longitudinal axis (6) and extending essentially along said tip region (4), and a coil (7) arranged in said tip region (4). The coil (7) at least partly encloses said tip region core wire (5), and a distal tip joint (8) is arranged at a distal end (9) of said sensor guide wire (1) for attaching said coil (7) to said tip region core wire (5). A major part of said tip region core wire (5) has a circular cross-section in a plane perpendicular to said longitudinal axis (6).
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Boye, Shawn
Abstract
A sensor element comprises a sensor section comprising a sensor unit configured to measure a physiological variable or any other signal in a living body and to generate a sensor signal in response to the variable or other signal, and a bond section comprising contact members configured to electrically connect at least one signal transmitting microcable. The bond section is coated with an electrically insulating material and the sensor unit is left uncoated. The sensor element may further comprise an intermediate section between the sensor section and the bond section. The intermediate section includes electric connection lines configured to connect the contact members to the sensor unit. The intermediate section is also coated with the electrically insulating material.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hilmersson, Mats
Abstract
A sensor guide wire includes a sensor element arranged in a jacket in a sensor region of the sensor guide wire; a core wire extending at least partly along a length of the sensor guide wire; and at least one electrical lead connected to the sensor element. The jacket is tubular and includes proximal and distal end openings, a jacket wall, a first opening arranged in the jacket wall, and a second opening arranged in the jacket wall, the first and second openings being proximate to the sensor element. The core wire is adapted to extend through the jacket via the proximal and distal end openings. At least a portion of the first opening and at least a portion of the second opening are both located in the same cross-section of the sensor guide wire, the cross-section being perpendicular to the longitudinal axis of the sensor guide wire.
St. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Dahlberg, Mattias
Adenmark, Tobias
Abstract
The present invention relates to a femoral compression system (14) for applying compression against a puncture site of a vessel in a patient, and a method for applying compression with a femoral compression system. The compression system (14) comprises an inflatable compression element (15) adapted to apply a pressure against the puncture site, a tightening unit (23) adapted to extend around a part of, or the whole of, the patients body to fixate and to tighten the compression element (15) against the puncture site, a pump (16) adapted to inflate the compression element (15), a valve (17) adapted to deflate the compression element (15), a pressure transducer (18) adapted to sense the pressure within the compression element (15). The system further comprises a blood pressure pulse detector (19) adapted to sense the patient's blood pressure pulse and to generate a pulse signal in dependence thereto that is applied to a control unit (20) that is connected to the pump (16), valve (17) and pressure transducer (19), wherein the control unit (20) is adapted to control the pressure within the compression element (15) in dependence of the pulse signal, by applying control signals to said pump (16) and valve (17).
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
51.
Male connector and a method of producing the male connector
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Mahlin, Fredrik
Abstract
The present invention relates to an elongated male connector (1), for a medical device, and a method of producing the male connector (1). The male connector (1) has a longitudinal axis (2) and comprises a plurality of conductive members (3), each having an outer contact surface (4) and being separated from each other by insulating members (5). The conductive and insulating members (3, 5) are disposed along the male connector (1), such that the outer contact surfaces (4) are arranged essentially at the same surface level, and that each of the conductive members (3) has an elongated extension along the longitudinal axis (2) of the male connector (1). Each conductive member (3) is provided with an insulated microrod (6) extending at least partially along the length of the male connector (1), and the conductive members (3) are hollow and have an essentially cylindrical cross-section and form, together with the insulating members (5), a self-supporting male connector (1) having no core wire.
H01R 24/58 - Contacts spaced along longitudinal axis of engagement
H01R 43/16 - Apparatus or processes specially adapted for manufacturing, assembling, maintaining, or repairing of line connectors or current collectors or for joining electric conductors for manufacturing contact members, e.g. by punching and by bending
H01R 43/24 - Assembling by moulding on contact members
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Abstract
Sensor guide wire for intravascular measurements of a physiological variable in a living body, comprising a core wire running along at least a part of the sensor guide wire and a sensor element arranged in a jacket in a sensor region of the sensor guide wire. The jacket is tubular and is provided with a jacket wall and a portion of the core wire that extends longitudinally along the sensor region forms part of the wall of the jacket, in order to provide more space in the jacket.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Atthoff, Björn
Hansson, Erik
Preinitz, Fredrik
Mahlin, Fredrik
Abstract
The invention relates to a compression unit adapted to be arranged around a patient's forearm to provide pressure to a radial artery puncture site, wherein the compression unit comprises a unit attachment band provided with a frame, and a compression element in the shape of an inflatable bladder, the compression element is further adapted to be arranged within said frame, such that when the compression unit is arranged around a patient's forearm, the compression element provides pressure to the puncture wound when the compression element is inflated. The invention also relates to a radial artery compression system.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
54.
Sensor guide wire device and system including a sensor guide wire device
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Abstract
A sensor guide wire device (200) for intravascular measurements of a physiological variable in a living body is disclosed. The sensor guide wire (200) may comprise a sensor element (213) and a connector unit (220). The connector unit (220) is attachable to a signal converting device (310). The sensor element (213) provides the signal converting device (310) with a signal indicative of a physiological variable sensed by the sensor element (213). Furthermore, the connector unit (220) comprises a battery (222). A system (300) comprising the sensor guide wire device (200) and the signal converting device (310) is also disclosed.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Smith, Leif
Abstract
A pressure sensor wire assembly measures pressure inside a body of a patient. The assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal representative of the pressure, and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. A sensor signal adapting circuitry is an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry which is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Adenmark, Tobias
Abstract
A femoral compression device (11) for compressing a femoral artery (12) of a patient, having a base plate (13) provided with two opposing extensions, each of the two opposing extensions having a member for affixing a belt (14), which is adapted to be arranged around a patient's body, an inflatable air cushion (15), provided with a back plate (19), for compressive bearing against a puncture site, and a pump (16) connected to the inflatable air cushion for inflation of the air cushion. The femoral compression device further comprises a spacer (18) having a height and being adapted to be mounted between the inflatable air cushion and the base plate.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
St. Jude Medical Coordination Center BVBA (Belgium)
Inventor
Atthoff, Björn
Hansson, Erik
Preinitz, Fredrik
Mahlin, Fredrik
Abstract
Dorsal forearm plate having a three-dimensional concave shape adapted to the shape of the dorsal forearm such that the dorsal forearm may rest on the forearm plate, the dorsal forearm plate has an essentially rectangular extension having opposing long sides and opposing short sides and has a substantially rigid unitary body adapted to underlie the posterior of the patient's hand, wrist and forearm, the plate is provided with two attachment bands, a distal and a proximal attachment band, adapted to attach the plate at the dorsal forearm of a patient. The shape of the side of the plate adapted to face the forearm during use, is adapted to the anatomy of the forearm in that it comprises two elongated depressions running in the longitudinal direction of the plate such that, during use of the plate, the ulnar bone and radius bone of the patient rest in the respective depression and that an elongated ridge, formed between the depressions, is adapted to extend into the softer tissue between the bones in order to orient and stabilize the forearm when attached to the plate. The invention also relates to a radial artery compression system comprising a dorsal forearm plate and a compression unit.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire (401) and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a first sensor (408A) and a second sensor (408B) disposed within the insertable portion at a distal end of the sensor wire. The first sensor measures a physiological parameter (blood pressure or temperature or blood flow) and the second sensor measures a non- physiological parameter (magnetic field or magnetic flux or x-ray field) for determining the position and orientation of the sensor wire. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Van Rens, Antonia Cornelia
Abstract
Medical guide wire assembly comprising a guide wire having a proximal end and a distal end, at least one physiology parameter sensor, and that the proximal end of the guide-wire is provided with an elongated connector part, having connection electrodes, for insertion into a connector housing provided with an elongated tubing adapted to achieve electrical and mechanical connection to the elongated connector part, the connector housing is in its turn electrically or wirelessly connectable to a physiology monitor. The guide wire is provided with a core wire running essentially along the entire guide wire. A sensor signal processing circuitry is arranged in connection with the physiological sensor and is adapted to generate a processed sensor signal in response of a sensed parameter. The sensor signal processing circuitry comprises a modulation unit arranged to modulate the processed sensor signal and to generate a modulated sensor signal. The assembly comprises exactly two micro-cables that are connected to the sensor signal processing circuitry, the micro-cables run along the guide wire and are connected to the connection electrodes of the connector part, wherein one of the core wire and the two micro-cables are actively used when transferring the processed and modulated sensor signal to the connector housing.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Abstract
Medical guide wire assembly comprising a guide wire having a proximal end and a distal end, at least one physiology parameter sensor, and that the proximal end of the guide-wire is provided with an elongated connector part, having connection electrodes, for insertion into a connector housing provided with an elongated tubing adapted to achieve electrical and mechanical connection to the elongated connector part, the connector housing is in its turn electrically or wirelessly connectable to a physiology monitor. The guide wire is provided with a core wire running essentially along the entire guide wire. A sensor signal processing circuitry is arranged in connection with the physiological sensor and is adapted to generate a processed sensor signal in response of a sensed parameter. The sensor signal processing circuitry comprises a modulation unit arranged to modulate the processed sensor signal and to generate a modulated sensor signal. The assembly comprises exactly two micro-cables that are connected to the sensor signal processing circuitry, the micro-cables run along the guide wire and are connected to the connection electrodes of the connector part, wherein the core wire is actively used when transferring the processed and modulated sensor signal to the connector housing.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Düring, Erik
Karlsson, Staffan
Abstract
A guide wire assembly includes a proximal end portion, a distal portion comprising a coil, a hollow stranded wire extending towards the distal portion, and a core wire. The guide wire assembly is characterized in that a proximal tube is provided, which extends from the proximal end portion to a proximal end of the hollow stranded wire such that the hollow stranded wire is directly joined to the proximal tube. The core wire extends into the distal portion and does not extend into the proximal tube. An entire length of the hollow stranded wire is in a range of 7.5 to 22.5% of an entire length of the guide wire assembly.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hubinette, Ulrik
Samuelsson, Magnus
Abstract
The present invention relates to an eavesdropping device for monitoring measured physiological variables of an individual, which eavesdropping device comprises a receiver and a communication interface. The eavesdropping device of the present invention is typically applied in a system comprising a first sensor arranged to be disposed in or outside the body of the individual for measuring aortic blood pressure Pa, and a second sensor arranged for measuring distal blood pressure Pd. Further, the system comprises a central monitoring device for monitoring the measured physiological variables and a communication link between the sensors and the central monitoring device for communicating signals representing the measured physiological variables from the sensors to the central monitoring device. The eavesdropping device is configured such that the communication interface is arranged at the communication link to communicate at least the signal representing the aortic blood pressure to a monitor of the eavesdropping device. Moreover, the receiver of the eavesdropping device is connected to the communication link, in parallel with the central monitoring device. The signal representing the aortic blood pressure Pa is communicated to the receiver via a high-impedance connection at the communication interface, and the receiver of the eavesdropping device is further arranged to receive the signal representing the measured distal blood pressure P d from the communication link. By means of the blood pressure signals of the respective sensor, FFR can be calculated.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Hübinette, Ulrik
Samuelsson, Magnus
Abstract
An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a high impedance connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Pijls, Nico H. J.
Abstract
The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system, comprises a sensor wire and a transceiver unit. The sensor wire comprises an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a variable inside the patient. The transceiver unit comprises: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module. The communication signal, including sensor values, is generated by the transceiver unit and transferred as a data stream. The housing is configured to remain external to the patient's body.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.
St. Jude Medical Coordination Center BVBA (Belgium)
Inventor
Smith, Leif
Abstract
A transmitter unit with an attachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The attachable energy source can be a battery pack or battery holder provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
H01R 24/66 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with pins, blades or analogous contacts and secured to apparatus or structure, e.g. to a wall
H01R 24/76 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with sockets, clips or analogous contacts and secured to apparatus or structure, e.g. to a wall
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Abstract
A male connector for a sensor guide wire for intravascular measurements of physiological variables in a living body, and a method for producing said male connector. The male connector comprises a plurality of spaced apart conductive members, extending at least partially along the length of the male connector, and a plurality of conductive areas separated from each other by insulating areas, disposed along the male connector, wherein each of the conductive members are connected to a respective conductive area. The conductive members and the conductive and insulating areas are formed on a planar sheet of thin flexible insulating material, and the conductive members are provided on one surface of the sheet and the conductive areas are provided on the other surface of the sheet, wherein said planar sheet is adapted to be formed into said male connector such that said conductive member being arranged at the inner surface, and that said conductive and insulating areas being arranged at the outer surface of the male connector.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Abstract
A sensor guide wire for an intravascular measurement of a physiological variable in a living body includes a sensor region in a distal part of the sensor guide wire, a sensor element arranged in the sensor region, a male connector at a proximal part of the sensor guide wire, a least one electrical micro-cable connecting the male connector to the sensor element, and an elongated guide wire body arranged between the sensor region and the male connector. The at least one electrical micro-cable extends essentially helically around the guide wire body along the length of at least a part of the guide wire.
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Smith, Leif
Abstract
There is a sensor guide wire (1) for intravascular measurements of physiological variables in a living body. The sensor guide wire (1) comprises at least two elongate sections, a first tubular elongate section (2) being tubular in the longitudinal direction of the sensor guide wire (1), and a second elongate section (3) that is adapted to be inserted a predetermined distance (5) into said first tubular section (2), a sensor element (10) provided in the distal part of said sensor guide wire (1), for measuring the physiological variable and to generate a sensor signal in response to said variable, at least one signal transmitting cable connected to the sensor element (10) to transmit sensor signals to a male connector provided in the proximal part of said sensor guide wire (1). The tubular section (2) is provided with at least one through-going opening (4) in a direction perpendicular to the longitudinal direction of the guide wire (1) and positioned a second predetermined distance (6) from one end of the tubular section (2), wherein the guide wire (1) comprises a locking member (7) to be fitted into the opening (4) in order to join the sections (2, 3) together when the second elongate section (3) is inserted into the tubular section (2).
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Smith, Leif
Abstract
A transmitter unit with a detachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The detachable energy source can be a battery pack provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Smith, Leif
Abstract
A pressure sensor wire assembly measures pressure inside a body of a patient. The assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal representative of the pressure, and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. A sensor signal adapting circuitry is an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry which is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tenerz, Lars
Smith, Leif
Abstract
The invention relates to a sensor and guide wire assembly for intravascular measurements within a living body, wherein a sensor element, which is arranged at a distal portion of a guide wire, comprises at least one piezoresistive nanowire.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Åkerfeldt, Dan
Smith, Leif
Lindström, Marie
Adenmark, Tobias
Abstract
A femoral compression device (1) for compressive bearing against the femoral artery of a patient, comprising a base plate (2), an inflatable air cushion (4), and an electronic manometer (8) connected to the inflatable air cushion for measurement of the current pressure difference between the pressure prevailing inside the inflatable air cushion and the ambient air pressure. The femoral compression device can further comprise a mechanical device (11; 46) which prevents an air opening leading to the inflatable air cushion from being closed before the manometer is zeroed. In another embodiment, an electronic manometer is provided such that a current characteristic of an electric signal representing the current pressure difference can be compared with a corresponding characteristic which was obtained at zero pressure difference and which was stored in the electronic manometer, wherein the manometer cannot be zeroed as long as the current characteristic deviates more than a predetermined amount from the stored characteristic.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Gustafsson, Pär
Abstract
The invention relates to a torque device for a sensor guide wire having a sensor provided at a distal portion and a male connector provided at the proximal end, which torque device comprises a grip body and a cap adapted to be joined to the grip body, and a number of chuck segments provided on the cap or the grip body, wherein the torque device is a one-way device defining an insertion direction for the sensor guide wire and wherein the chuck segments have free ends which are directed in the insertion direction.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
Pressure measurement system comprising a pressure sensor wire with a pressure sensor to measure pressure inside a patient, and to provide measured pressure data to an external device. The pressure sensor wire is adapted to be connected, at its proximal end, to a transceiver unit that is adapted to wirelessly communicate via a communication signal with a communication unit arranged in connection with an external device, in order to transfer measured pressure data to the external device. The pressure data to be transferred is generated by the transceiver unit and transferred as a data stream. Preferably, the communication signal is a radio frequency signal.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tulkki, Sauli
Tenerz, Lars
Abstract
The present invention relates to a sensor assembly arranged to be disposed in a body for measuring a physiological variable. A basic idea of the present invention is to provide a sensor and guide wire assembly which communicates with an external unit by an inductive coupling between a first coil provided in the sensor assembly and a second, external coil which is disposed in or connected to the external unit. The external unit is preferably the same unit that is used to numerically or graphically display the physiological variables that are measured with the sensor and guide wire assembly. With the terminology introduced above, it should here be clear that both the signal transfer from the sensor as well as the energy feeding from the external unit to the sensor may be accomplished through the inductive coupling between the first and second coils.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Pijls, Nico H.J.
Abstract
The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Samuelsson, Magnus
Tulkki, Sauli
Abstract
The present invention relates to a system and a method of measuring a physiological variable in a body. A basic idea of the present invention is to measure a physiological variable in a body by means of employing a sensor (314) which is arranged to be disposed in the body for measuring the physiological variable. The sensor must be provided with a supply voltage in order to be operable. Therefore, a control unit (322) disposed outside the body provides this supply voltage to the sensor. The control unit also receives, from the sensor, via a wired connection (311), signals that represent the physiological variables that are measured. The control unit is arranged with a communication interface (401, 701) and a modulator (301) for wireless spread spectrum communication of the measured physiological variables for presentation purposes.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tulkki, Sauli
Abstract
The invention relates to a sensor and guide wire assembly (20) for intravascular measurements of physiological variables in a living body, comprising a core wire (21) and a sensor element (22). The sensor and guide wire assembly (20) comprises further a jacket (25; 35; 45) provided with a first opening (26; 36; 46), in which at least a portion of the sensor element (22) is arranged, and a second opening (27; 37; 47), in which a portion of the core wire (21) is arranged, the first opening (26; 36; 46) and the second opening (27; 37; 47) being separated from each other.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Hammarström, Ola
Gustafsson, Pär
Abstract
During use there is a risk that a male connector for a guide wire is bent. With the present male connector (1) more material with high modulus of elasticity can be provided inside the male connector (1), which makes the male connector (1) more bending resistant. The male connector (1) comprises a core wire (3), a plurality of conductive members (4) spaced apart longitudinally along said core wire (3), a plurality of conductors (5) disposed along the core wire (3), each of the conductors (5) being connected to a respective conductive member (4). The core wire (3) has such a shape that least one longitudinal cavity is provided, which longitudinal cavity remains substantially intact when the male connector (1) is bent, thereby protecting the conductors (5), which are disposed in said cavity, from being damaged.
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Von Malmborg, Pär
Hammarström, Ola
Gustafsson, Pär
Abstract
During use there is a risk that a male connector for a guide wire is bent. With the present male connector (1) more material with high modulus of elasticity can be provided inside the male connector (1), which makes the male connector (1) more bending resistant. The male connector (1) comprises a core wire (3), a plurality of conductive members (4) spaced apart longitudinally along said core wire (3), a plurality of conductors (5) disposed along the core wire (3), each of the conductors (5) being connected to a respective conductive member (4). The connector (1) has such a configuration that the conductors (5) are protected from damage at the location where the conductors (5) connect to the conductive members (4).
ST. JUDE MEDICAL COORDINATION CENTER BVBA (Belgium)
Inventor
Tenerz, Lars
Von Malmborg, Pär
Abstract
The present invention relates to a measuring device, insertable into a living body. The device includes an elongated flexible member in the form of a thick-walled hollow tube with a proximal end and a distal end. The tube defines a central lumen with an inner wall. The lumen may contain a core and an insulating material provided between the core and the inner wall. The core may be made of an electrically conductive material and may be of essentially constant diameter over its entire length. Alternatively, the lumen may contain at least two electrical leads. An electrical sensor is attached to the distal end of the elongated flexible member and is electrically connected to the core.
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