Disclosed is use of a combined compound medicine in treating pathogenic bacteria persistent infection. Existing antibiotic monotherapy or combination therapy is usually difficult to kill pathogenic bacteria in the persister state, especially nutrient-insensitive persister bacteria, which often lead to a series of problems of long treatment period, frequent condition recurrence and deterioration, treatment failure, drug-resistant mutation, etc. At present, drugs capable of efficiently killing highly persistent pathogenic bacteria in a clinically applicable concentration range are still unavailable. The novel compound medicine of polymyxin and aminoglycoside antibiotics disclosed in the present disclosure without precedence is capable of destroying bacterial cell membranes in a short time within a relatively wide range of clinically achievable plasma concentrations, leading to rapid death of a large number of bacteria, but is safe for human-derived cells. Therefore, the compound medicine is expected to be applied to the clinical treatment of various acute or chronic infectious diseases caused by pathogenic bacteria in the persister state, shortening the treatment course, preventing the recurrence of infection recurrence, and slowing down the emergence of drug-resistant mutations.
A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
A61K 31/702 - Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
WEIQIAO LIGHTWEIGHT RESEARCH CENTER AT SOOCHOW (China)
Inventor
Wang, Dongtao
Nagaumi, Hiromi
Zhang, Bo
Chen, Lai
Abstract
The present invention relates to a high temperature-resistant cast aluminum alloy, a preparation method therefor and a use thereof, belonging to the technical field of aluminum alloys. The elemental composition and mass percentages thereof in the high temperature-resistant cast aluminum alloy of the present invention are as follows: Si: 1%-10%, Cu: 0.1%-4%, Mg: 0.05%-0.5%, Fe: 0.05%-0.3%, Ti: 0.01%-0.3%, Mn: 0.1%-0.5%, Cr: 0.01%-0.6%, V: 0.02%-0.2%, Sn: 0.02%-0.2%, Sc: 0.02%-0.2%, Hf: 0.02%-0.2%, Er: 0.02%-0.2%, and the balance being unavoidable impurities and Al; the microstructure of the high-temperature resistant cast aluminum alloy comprises a submicron precipitate phase and/or a nano precipitate phase. By means of controlling the alloy composition, proportioning and preparation method, and reasonably configuring parameters for heat treatment and aging treatment, while simultaneously obtaining one or more high temperature-resistant coarsened precipitate phases of submicron and nanometer size having specific compositions, dimensions and characteristics, the strength of the aluminum alloy in high-temperature environments is effectively improved, and the high temperature resistance of the aluminum alloy is enhanced.
C22C 21/02 - Alloys based on aluminium with silicon as the next major constituent
C22C 21/16 - Alloys based on aluminium with copper as the next major constituent with magnesium
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
C22F 1/043 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon of alloys with silicon as the next major constituent
C22F 1/057 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon of alloys with copper as the next major constituent
C22C 1/03 - Making non-ferrous alloys by melting using master alloys
3.
SILICON-BASED ROOM-TEMPERATURE INFRARED HOT-ELECTRON PHOTODETECTOR, METHOD FOR PREPARING SAME, AND USE OF SAME
The invention provides a silicon-based room-temperature infrared hot-electron photodetector, preparation method and use thereof. The photodetector includes a base and a planar multi-layer structure. The planar multi-layer structure includes a bottom conductive electrode, a silicon film, a transition metal film, and a transparent dielectric film. The electrode and the silicon film form an ohmic contact and constitute an optical reflector. The silicon film and the transition metal film form a Schottky contact, the thickness of the silicon film is smaller than the depletion layer width of a Schottky junction formed by the silicon film and the transition metal film, the transition metal film absorbs near infrared light and generates hot electrons to be injected into the silicon film, and the hot electrons are collected by the electrode to form a photocurrent. The transparent dielectric film is used as an antireflection layer and can reduce reflection of incident light.
H01L 31/028 - Inorganic materials including, apart from doping material or other impurities, only elements of Group IV of the Periodic System
H01L 31/108 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by only one potential barrier or surface barrier the potential barrier being of the Schottky type
H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof
4.
METHOD FOR SLAG MODIFICATION DURING END PERIOD OF CASTING IN STEEL LADLE HAVING COVER
A method for slag modification method during the end period of casting in a steel ladle having a cover is disclosed. When the slag in a steel ladle is reducing slag, before casting, air is blown into the steel ladle by means of a bottom blowing brick, then casting is started, and during the end period of casting, bottom blowing of gas is stopped, and a carrier gas is used to spray a modifier into the steel ladle until casting is completed. When the slag is oxidizing slag, during the end period of casting, the carrier gas is used to spray the modifier into the steel ladle until casting is completed. The direction in which the modifier is sprayed is towards a steel outlet of the steel ladle, the modifier being lime, light calcined dolomite, magnesium balls, or recarburizer, and the particle size of the modifier being 3-10 mm.
The present invention relates to the technical field of flexible electronics, and relates to a breathable and stretchable circuit capable of being activated by imprinting, and a preparation method therefor and a use thereof. The preparation method for the breathable and stretchable circuit capable of being activated by imprinting in the present invention comprises the following steps: dissolving a thermoplastic polymer in a solvent, adding liquid metal particles, and mixing and dispersing to obtain a mixed solution; carrying out electrospinning on the obtained mixed solution to prepare a nanofiber membrane; and using a stamping model having a circuit pattern to stamp the obtained nanofiber membrane so as to obtain the breathable and stretchable circuit capable of being activated by imprinting. The present invention ensures the breathability and the stretchability by using the nanofiber membrane. The liquid metal particles match fibers in diameter, and therefore, liquid metal in nanofibers can be overflowed by means of imprinting to form a conductive path, achieving high-precision preparation of circuits.
D01F 6/94 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of other polycondensation products
D01F 6/48 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polymers of halogenated hydrocarbons
B25J 19/00 - Accessories fitted to manipulators, e.g. for monitoring, for viewingSafety devices combined with or specially adapted for use in connection with manipulators
D04H 1/728 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
D04H 1/4382 - Stretched reticular film fibresComposite fibresMixed fibresUltrafine fibresFibres for artificial leather
D01D 5/00 - Formation of filaments, threads, or the like
H05K 3/12 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using printing techniques to apply the conductive material
H05K 3/00 - Apparatus or processes for manufacturing printed circuits
6.
AIR-PERMEABLE STRETCHABLE CIRCUIT WHICH CAN BE ACTIVATED BY STAMPING, PREPARATION METHOD AND USE THEREOF
The present invention relates to an air-permeable stretchable circuit, which can be activated by stamping, preparation method and use thereof, belonging to the field of flexible electronic technology. The preparation method includes steps of: dissolving a thermoplastic polymer in a solvent, then adding liquid metal particles and mixing to obtain a mixed solution; performing electrospinning on the mixed solution to prepare a nanofiber membrane; performing stamping on the nanofiber membrane with a stamping mould having a circuit pattern, to obtain the air-permeable stretchable circuit. The invention ensures air-permeability and stretchability through using nanofiber membranes. Due to the matching diameters of the liquid metal particles and the fibers, stamping can cause the liquid metal inside the nanofibers to overflow and form conductive paths, thereby achieving high-precision preparation of circuits.
H05K 3/12 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using printing techniques to apply the conductive material
D01D 5/00 - Formation of filaments, threads, or the like
D04H 1/4382 - Stretched reticular film fibresComposite fibresMixed fibresUltrafine fibresFibres for artificial leather
D04H 1/728 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
Suzhou Shuda Innovation Medical Technology Co., Ltd. (China)
Inventor
Fei, Min
Wu, Yingchao
Li, Weiwei
Cao, Yifeng
Lu, Kaiye
Yan, Waner
Fei, Zhaoqin
Zhu, Dongning
Lu, Lijun
Abstract
Provided are a primer and probe composition for cat blood type detection, a detection method, and use. The primer and probe composition for detecting the wild-types and the mutants of the above four sites is designed according to the single nucleotide polymorphism (SNP) mutation of genotyping of 179G>T, 268T>A, 364C>T and 1322delT four sites of a cat cytidine monophospho-N-acetylneuraminic acid (CMAH) gene; an amplification curve is plotted by utilizing a real-time fluorescence polymerase chain reaction (PCR) technology, and the recognition of bases of four SNP sites is achieved by analysis of the amplification curve, so as to determine cat blood types. The detection method of the present disclosure is carried out entirely in a closed space, thereby avoiding the problem of environmental aerosol pollution.
Disclosed are a Pulsatilla saponin B4 derivative, a preparation method therefor, and a use thereof. A compound Pulsatilla saponin B4 (referred to as B4 or AB4) is used as a raw material, a nucleophilic substitution reaction, an electrophilic addition reaction, an esterification reaction, or an amidation reaction is separately performed on a C-19 exocyclic double bond or a C-28 carboxyl group to prepare a derivative, and the derivative is used as an active ingredient to prepare a drug having anti-inflammatory and immunomodulatory effects. In the present invention, it is disclosed for the first time that the B4 derivative has the effect of treating inflammatory diseases such as inflammatory bowel disease, atopic dermatitis, eczema, and psoriasis, and the effect is superior to that of B4 or a clinically common drug. In addition, it is also disclosed for the first time that most B4 derivatives do not show obvious cytotoxicity to macrophages, and can reduce the level of P-IκBa protein in LPS and ATP-induced macrophage NF-κB signaling pathways, inhibit the activation of NLRP3 signaling pathways and obviously reduce the level of Pro-IL-1β (p<0.05), i.e., inhibiting the activation of an inflammasome pathway, and the effect is superior to that of B4. These results show that the B4 derivative of the present invention has better anti-inflammatory activity.
A nano-composite material-based intelligent fireproof textile and a preparation method therefor. Titanium aluminum carbide powder is added into a mixed solution of hydrochloric acid and lithium fluoride, and a reaction takes place under the condition that the temperature of a water bath is 40-50° C.; the reactants are washed to be neutral, centrifugation is performed, a precipitate is ultrasonically dispersed in deionized water, ammonium molybdate powder is added, irradiation under ultraviolet light is performed, and dialyzing and drying are performed, to obtain a molybdenum oxide quantum dot titanium carbide composite material, which is dispersed as a nano-slurry, and a rolling-baking-roasting process is used to finish a pretreated fabric, to obtain a nano-composite material-based intelligent fireproof textile. The molybdenum oxide quantum dot titanium carbide composite material is prepared on the basis of etching and ion intercalation principles, and it is combined with the fabric via post-finishing, so that the textile has fire early warning and smoke suppression functions, which is beneficial for the further application of functionalized nano-materials in the field of textiles.
D06M 11/48 - Oxides or hydroxides of chromium, molybdenum or tungstenChromatesDichromatesMolybdatesTungstates
D06M 11/74 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with carbon or graphiteTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with carbidesTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with graphitic acids or their salts
10.
Method for preparing nanosized mixed crystal of cyanuric acid coated halide perovskite and use thereof
The invention provides a method for preparing a nanosized mixed crystal of cyanuric acid-coated halide perovskite, and use thereof. The method includes: (1) dispersing cesium halide, a lead salt, and urea in water, and stirring to obtain a mixed solution; and (2) adding phosphoric acid to the mixed solution, and subjecting to microwave heating, to obtain a solid after water is evaporated off, which is allowed to stand to obtain the nanosized mixed crystal of cyanuric acid coated halide perovskite. The method is simple, reproducible, and low in cost, with which mass production is achievable, and the emission wavelength of the obtained product is adjustable within a certain range through heat treatment. Due to the passivation and protection effects of cyanuric acid on halide perovskite, the prepared nanosized mixed crystal has excellent luminescence performance and stability, and is useful in the preparation of a high-color-point quantum dot brightness enhancement film.
C09K 11/02 - Use of particular materials as binders, particle coatings or suspension media therefor
C09K 11/66 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing germanium, tin or lead
C09K 11/88 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing selenium, tellurium or unspecified chalcogen elements
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
B82Y 40/00 - Manufacture or treatment of nanostructures
The present invention relates to a diffractive optical waveguide and a display module. The diffractive optical waveguide comprises a waveguide substrate, the waveguide substrate comprising an in-coupling region and an out-coupling region. The direction from the in-coupling region to the out-coupling region is a first direction. The out-coupling region comprises a first sub-out-coupling region and a second sub-out-coupling region. The first sub-out-coupling region comprises at least two first out-coupling blocks which are sequentially arranged in the first direction, and efficiency modulation functions of the at least two first out-coupling blocks present a progressive trend in the first direction. In a direction perpendicular to the first direction, the second sub-out-coupling region comprises at least two second out-coupling blocks which are sequentially arranged in a direction away from the first sub-out-coupling region, and efficiency modulation functions of the at least two second out-coupling blocks present a progressive trend in the direction away from the first sub-out-coupling region. In the diffractive optical waveguide of the present invention, efficiency partitioning can be separately performed on the first sub-out-coupling region and the second sub-out-coupling region, thereby improving the uniformity of brightness among different observation images in the range of an eyebox.
A naked-eye three-dimensional (3D) display device (600) is provided. The naked-eye 3D display device (600) comprises: a display component (610), comprising an array of display units (110); and a viewing angle regulator (620), comprising an array of microprism blocks (120, 620-1, 620-2, 620-3, 620-4, 620-5, 620-6). The microprism blocks (120, 620-1, 620-2, 620-3, 620-4, 620-5, 620-6) are divided into a plurality of groups, and an angle combination of a first angle (θ1) and a second angle (θ2) of each of the microprism blocks (120, 620-1, 620-2, 620-3, 620-4, 620-5, 620-6) is preset so that outgoing lights of the same group of microprism blocks converge into the same viewpoint, and outgoing lights of different groups of microprism blocks converge into different viewpoints. Hence, a plurality of different viewpoints are formed by setting angles of inclined surfaces of the microprism blocks (120, 620-1, 620-2, 620-3, 620-4, 620-5, 620-6), thereby seeing different 3D display effects from different viewing angles.
G02B 30/36 - Stereoscopes providing a stereoscopic pair of separated images corresponding to parallactically displaced views of the same object, e.g. 3D slide viewers using refractive optical elements, e.g. prisms, in the optical path between the images and the observer
13.
DIVALENT INORGANIC METAL ION/PHOTOSENSITIZER PROTEIN NANOPARTICLE, AND PREPARATION THEREFOR AND USE THEREOF
Disclosed in the present invention are a divalent inorganic metal ion/photosensitizer protein nanoparticle, and a preparation therefor and the use thereof. In the present invention, a new technical train of thought is utilized to effectively solve the present defect whereby the immunotherapy effect can only be exerted when a delivered high-valence inorganic oxide is reduced to a divalent state in cells. The nanoparticle is successfully prepared at room temperature in a water solution with a certain pH, and the divalent inorganic metal ion and the photosensitizer entrapped in the nanoparticle form a complex. The nanoparticle has the advantages of stable metal-ion valence and small size, can penetrate deep into tumor tissue via a blood vessel wall, releases the divalent inorganic metal ion after being quickly dissociated in the subacid environment of a lysosome, and plays a phototherapy role. The nanoparticle can damage a lysosome membrane, and breaks through a lysosome barrier to directly transfer Mn2+ to cytoplasm, so that after illumination, the release of double-stranded DNA is induced, cGAMP is generated in-situ in the cytoplasm, a STING signal pathway is activated, the immune response rate is improved, and the treatment effect of the tumor immunotherapy is enhanced. Experiments verify that tumor growth can be completely suppressed in a mouse in-situ breast cancer model.
Provided are a derivative of pentacyclic triterpenoidal saponin, a preparation method therefor, and a use thereof. A compound A3 is used as a raw material, a derivative is prepared by targeting a carboxyl group of C-28 and using an esterification reaction or amidation reaction, and said derivative is used as an active ingredient to prepare drugs having anti-inflammatory, antioxidant and anti-apoptotic effects. The derivative of pentacyclic triterpenoidal saponin does not show obvious cytotoxicity to macrophages, has better anti-inflammatory activity, and can alleviate the symptoms of colitis in mice. In addition, said derivative antagonizes the cytotoxicity of cisplatin and can significantly inhibit the release of reactive oxygen species (ROS) in renal cells caused by cisplatin.
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
15.
METHOD FOR IN-SITU MONITORING OF PROGRESS OF PHOTOCHEMICAL CYCLOADDITION REACTION BY MEANS OF FLUORESCENCE SPECTROSCOPY
The present invention relates to the field of the monitoring of photochemical cycloaddition reactions, and relates to a method for in-situ monitoring of the progress of a photochemical cycloaddition reaction by means of fluorescence spectroscopy. The method for in-situ monitoring of the progress of a photochemical cycloaddition reaction by means of fluorescence spectroscopy of the present invention comprises: preparing a fluorescent material that can be subjected to a photochemical cycloaddition reaction; causing the fluorescent material to be subjected to a photochemical cycloaddition reaction under the irradiation of ultraviolet visible light; monitoring a fluorescence change of the material by means of fluorescence spectroscopy; and performing in-situ monitoring on the photochemical cycloaddition reaction to monitor the reaction progress of the occurred photochemical reaction. Compared with conventional in-situ monitoring technology, the method for in-situ monitoring of the progress of a photochemical cycloaddition reaction by means of fluorescence spectroscopy has the advantages of being simple to operate, rapid and efficient, and easy to capture signals, having a wide range of application, and reducing the experimental costs and the operation difficulty.
A fabric wet power generation material based on molybdenum disulfide and a preparation method and use therefor. Taking molybdenum disulfide as a base material, an in-situ grown MoS2 carbonized fabric and a MoS2-based conductive cellulose fiber fabric are prepared by using a hydrothermal method. Then the two fabrics are superposed to form a double-potential layer, so that under a wet condition, the textile uses water evaporation as a driving force, and the water molecules migrate in the double-conductive layers to generate a current, so as to achieve self-power generation, and the fabric wet power generation material is prepared. The fabric wet power generation material provided by the present invention uses metal as a negative electrode, and after being packaged, the fabric wet power generation material is applied to a wet power generation apparatus. In the fabric wet power generation material provided by the present invention, a transition metal disulfide nanomaterial having a three-dimensional micro-channel structure is constructed on the nano scale, and the structure ensures a large moisture conduction conductivity; meanwhile, a large number of pore channels existing in the three-dimensional structure can shorten the ion transmission distance, so that the power generation performance is improved, and there are advantages of being simple and rapid in preparation process and high in yield, and being beneficial to industrial production and application in the field of flexible intelligent textile.
Provided is a method for preparing spider and Bombyx mori composite silk fibers on the basis of gene targeting Bombyx mori, particularly a method for preparing composite silk fibers of spider major ampullate spidroin and Bombyx mori fibroin on the basis of gene targeting Bombyx mori. The method comprises injecting pUC-target-Heavy-g and plasmid piggyCPF1 expressing Cas12a nuclease into the primary eggs of Bombyx mori, and performing primary fluorescent screening, molecular biological identification and subculture screening to obtain a gene targeting Bombyx mori in which the Bombyx mori fibroin heavy chain gene expression cassette is replaced by the spider major ampullate spidroin gene sequence expression cassette. The gene targeting Bombyx mori is conventionally fed, matured Bombyx mori are moved to a cocooning frame and make cocoons, the cocoons are harvested, and silk reeling is performed to obtain the composite silk containing Nephila clavipes major ampullate spidroin.
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
18.
DEPOLYMERIZATION CYCLIZATION METHOD FOR AROMATIC POLYESTER
A depolymerization cyclization method for an aromatic polyester. The depolymerization cyclization method comprises the following steps: mixing an aromatic polyester with a high-boiling-point environmentally friendly solvent and a catalyst, heating and dissolving the mixture to subject the aromatic polyester to a depolymerization cyclization reaction so as to obtain the corresponding cyclic oligoester, wherein the high-boiling-point solvent is an environmentally friendly solvent that does not contain a halogen or an aromatic group, such as 1,3-dimethyl-2-imidazolinone, the heating temperature is 180-250ºC, the catalyst is an organic base catalyst, and the yield of the separated and purified cyclic oligoester can reach 91%. The depolymerization cyclization method for an aromatic polyester can be used for the chemical recycling of a polyester; and by using an environmentally friendly solvent as a reaction solvent, a recycled aromatic polyester is depolymerized under the catalysis of the organic base catalyst to obtain the aromatic cyclic oligoester, thereby achieving the environmentally friendly chemical recovery of an aromatic polyester, which lays a foundation for the recycling and high-value utilization of an aromatic polyester.
The present application provides a respiration feature extraction method based on body surface significance analysis, including: establishing a body surface voxel model of chest and abdomen respiration motion, which includes acquisition of point cloud information, generation of the voxel model and extraction of respiration motion features; establishing a significance evaluation function by performing significance analysis on different regions of a body surface, and selecting the body surface region with high correlation with tumor motion based on the evaluation function; and performing voxelization on the body surface region, and obtaining effective one-dimensional characterization information of the body surface region using a local linear embedding dimension reduction algorithm. Compared with the prior art, the method avoids an influence of body-surface redundant motion information on precision of the association model, and compared with a PCC method, the method can avoid harm to the human body caused by continuous irradiation of X rays.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
20.
MICRO-PROJECTION SYSTEM BASED ON HYBRID REFRACTIVE-DIFFRACTIVE LENS
A micro-projection system based on a hybrid refractive-diffractive lens, relating to the technical field of near-eye display devices. A micro-projection lens set sequentially comprises, along an optical axis and from an exit pupil side (6) to an image source side (7), a first lens (1), a second lens (2), a third lens (3), and a fourth lens (4), wherein the first lens (1) is a plano-convex lens and protrudes toward the exit pupil side (6), the second lens (2) is a biconcave lens, the third lens (3) is a meniscus convex lens and protrudes towards the exit pupil side (6), and the fourth lens (4) is a biconvex lens. The first lens (1) has positive focal power, and is used for deflecting large-angle light rays. The second lens (2), the third lens (3), and the fourth lens (4) are cemented by means of an optical adhesive to form a hybrid refractive-diffractive lens; and the cemented surfaces of the second lens (2), the third lens (3), and the fourth lens (4) are each a superposition of an even asphere and a diffractive surface.
G03B 21/14 - Projectors or projection-type viewersAccessories therefor Details
G03B 21/00 - Projectors or projection-type viewersAccessories therefor
G02B 13/00 - Optical objectives specially designed for the purposes specified below
G02B 13/18 - Optical objectives specially designed for the purposes specified below with lenses having one or more non-spherical faces, e.g. for reducing geometrical aberration
A composite electrochromic material, a preparation method therefor and an application thereof, the material comprising a core layer, a skin layer having an electrochromic function, and a light-transmitting protective layer formed by a flexible polymer material, that are arranged in sequence. The material of the core layer comprises a fluid conductive mixture, which comprises liquid metal and carboxylated carbon nanotubes. The preparation method comprises: carrying out spinning by co-extrusion using a three-channel nozzle to form hollow double-layer fibers each having a skin layer and a protective layer as well as a cavity, injecting the conductive mixture into the cavity of the hollow double-layer fiber. The material has excellent deformation ability, stable and sensitive color changing function, and a controllable deformation degree. The material has a stable color changing function even in the case of severe defomation, good fatigue resistance, and is suitable for the preparation of intelligent textiles.
D01F 8/06 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers with at least one polyolefin as constituent
D01F 8/10 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers with at least one other macromolecular compound obtained by reactions only involving carbon-to-carbon unsaturated bonds as constituent
D01F 8/16 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers with at least one other macromolecular compound obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
D01F 8/18 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from other substances
D06M 11/74 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with carbon or graphiteTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with carbidesTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with carbon or compounds thereof with graphitic acids or their salts
D06M 11/83 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with metalsTreating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with metal-generating compounds, e.g. metal carbonylsReduction of metal compounds on textiles
D06M 101/20 - Polyalkenes, polymers or copolymers of compounds with alkenyl groups bonded to aromatic groups
D06M 101/24 - Polymers or copolymers of alkenylalcohols or esters thereofPolymers or copolymers of alkenylethers, acetals or ketones
D06M 101/30 - Synthetic polymers consisting of macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
22.
QUANTUM DOT ELECTROLUMINESCENT DEVICE HAVING LIGHT-EMITTING LAYER DISORDER‑GRADIENT AND MANUFACTURING METHOD THEREFOR
The present invention relates to the field of electroluminescent devices, and particularly relates to a quantum dot electroluminescent device having a light-emitting layer disorder-gradient. The device comprises a substrate, a device anode, a hole injection layer, a hole transport layer, a quantum dot light-emitting layer, an electron transport layer, and a device cathode which are sequentially arranged. The quantum dot light-emitting layer is formed by stacking a plurality of colloidal nanocrystal single-layer self-assembled films, each single-layer self-assembled film has the same density of electronic states distribution average energy and nanocrystal average size, and the density of electronic states distribution widths and nanocrystal size distribution widths of the highest occupied molecular orbital and the lowest unoccupied molecular orbital of each single-layer self-assembled film decrease monotonically in the normal direction of the substrate with the increase of the distance from a hole transport layer-quantum dot layer interface, and finally tend to be constant values. According to the solution, a breakthrough of the solution of boosting hole injection on the basis of an energy level matching theory is achieved, a hole injection barrier between the hole transport layer and the quantum dot layer is reduced by means of a disorder-gradient gradual change, and the light emitting performance of the device is improved.
H10K 50/115 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising active inorganic nanostructures, e.g. luminescent quantum dots
H10K 50/11 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers
23.
CARBON FOOTPRINT ACCOUNTING METHOD FOR SILK REELING STAGE OF RAW SILK
The invention relates to a carbon footprint accounting method for a silk reeling stage of raw silk, including establishing a mass conservation-based mass evolution relationship between a primary product and byproducts; calculating the process duration according to the mass of the primary product in processes, and combining equipment power to calculate a theoretical annual electricity consumption; calculating a total electricity consumption for each specification of raw silk based on the running efficiency; establishing a step-by-step allocation method for electricity consumption at byproducts generation points; establishing allocation rules and ratios for other energy and material inputs; and performing carbon footprint accounting for different silk specifications according to the allocated annual electricity consumption and the other allocated inputs. The invention changes a conventional practice of simply allocating carbon footprints of final products based on economic value, and achieves precise calculation and allocation of carbon footprints during the silk reeling stage.
THE SECOND XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY (China)
Inventor
Ye, Na
Cheng, Yan
Zhao, Xiaobao
Zhong, Changxin
Abstract
1212122 may be the same or different. The present invention designs and synthesizes the compounds having the structure shown as general formula (A) and finds that said compounds exhibit relatively strong binding capacity and in-vitro cell inhibition activity on eEF2K and also have good selectivity. The present invention more deeply and comprehensively discloses and illuminates the relationship between the structure and activity of said compounds to a more extensive range and thus has more important application value. When acting on eEF2K, the compounds of the present invention can be used for treating malignant tumors.
C07D 253/075 - Two hetero atoms, in positions 3 and 5
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 413/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 417/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 239/54 - Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
Provided relates to a depth video linkage feature-based behavior recognition method, comprising projecting a depth video of each behavior sample onto a front-side, a right-side, a left-side and a top-side; obtaining a dynamic image of each behavior sample by calculating a dynamic image of each projection sequence; inputting the dynamic image of each behavior sample into a respective feature extraction module and extracting features; inputting the extracted features into a multi-projection linkage feature extraction module and extracting a linkage feature of each projection combination; connecting all the extracted linkage features by channel, and inputting the connected features into an average pooling layer and a fully connected layer; constructing a depth video linkage feature-based behavior recognition network; inputting a depth video of each training behavior sample into the depth video linkage feature-based behavior recognition network, and training the network till convergence; and inputting a depth video of each behavior sample.
G06V 40/20 - Movements or behaviour, e.g. gesture recognition
G06V 10/50 - Extraction of image or video features by performing operations within image blocksExtraction of image or video features by using histograms, e.g. histogram of oriented gradients [HoG]Extraction of image or video features by summing image-intensity valuesProjection analysis
G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
The present application relates to a touch-control display technique, and particularly relates to a photoelectrical functional component, a touch display screen comprising a photoelectrical functional component, and an electronic apparatus. The photoelectrical functional component according to an aspect of the present application comprises: a substrate; and a single electrical functional layer, which is located on a first surface of the substrate. The photoelectrical functional component further comprises one or more optical functional layers, wherein each of the optical functional layers is located at one of the following positions: 1) between the substrate and the electrical functional layer; 2) above a second surface of the substrate, the second surface being opposite to the first surface; and 3) above the surface of the electrical functional layer that is opposite to the first surface. By means of the photoelectrical functional component of the present application, an angle of view can be enlarged by means of the adjustment and control function of an optical functional layer for a light field of light, which is incident to the component, significant attenuation of the brightness of a picture at a large angle of view can also be suppressed, and touch interaction can further be achieved by means of an electrical functional layer.
The invention provides a composite polymer film material based on a tungsten/copper/sulfur cluster compound, a preparation method and use thereof. The cluster compound has a chemical formula of: [RWS3Cu2(La)]n(M)n, wherein R is tris(3,5-dimethylpyrazolyl)hydroborate, tris(pyrazolyl)hydroborate, or pentamethylcyclopentadienyl; La has a structural formula of:
The invention provides a composite polymer film material based on a tungsten/copper/sulfur cluster compound, a preparation method and use thereof. The cluster compound has a chemical formula of: [RWS3Cu2(La)]n(M)n, wherein R is tris(3,5-dimethylpyrazolyl)hydroborate, tris(pyrazolyl)hydroborate, or pentamethylcyclopentadienyl; La has a structural formula of:
when M is perrhenate, n is 4; and when M is triflate, n is 6. The synthesis process of the cluster compound is simple and controllable. A tetrahedral and an octahedral tungsten/copper/sulfur cluster compound that are good third-order nonlinear optical (NLO) active species are selectively synthesized by using different cuprous salts. Composite polymer films of various layers are prepared by spin coating. Such films, as flexible, portable and easy-to-process solid materials, are applicable to third-order NLO devices. With increasing layers in the film, the third-order NLO response is gradually enhanced, and is 3-4 orders of magnitude higher than a solution containing the cluster compound.
The present invention relates to a high-resolution quantum dot pixelated light-emitting thin film and a preparation method therefor, and belongs to the technical field of quantum dots. The method comprises: spin-coating a substrate with a photoresist; drying the substrate; exposing the substrate by using a photoetching device; coating a preset position on the substrate with a developing agent to obtain a photoresist pattern layer; depositing an insulating layer on the photoresist pattern layer by using silane; removing the photoresist pattern in the insulating layer; spin-coating the insulating layer with a PEI solution to obtain a PEI layer; and dropping a QD solution on the PEI layer to deposit a QD layer. In the present invention, by means of the hydrophobicity of silane, a dewetting effect is achieved so as to achieve pixelation of the quantum dots; by means of the hydrophobicity of the insulating layer, the PEI solution is spontaneously deposited to the position of the photoresist pattern; and the QD solution is adsorbed into the PEI solution on the basis of the electrostatic interaction between the QD solution and the PEI solution, such that a high-resolution quantum dot pixelated light-emitting thin film is obtained, the film forming quality is improved, and surface defects of a QD layer are passivated.
A drug co-loaded polymer vesicle, and a preparation method therefor and the use thereof. A polymer vesicle double-drug nano preparation is obtained by means of the self-assembly and self-crosslinking of an amphiphilic block polymer and the co-loading of anti-tumor drugs at the same time. The drug co-loaded polymer vesicle has the advantages of a simple and controllable preparation, an adjustable drug ratio, a small size, easy storage, high stability, excellent biocompatibility, a rapid and proportional drug release in cells, a strong synergistic anti-tumor effect, high in-vivo safety, being capable of completely eradicating tumors, etc. In general, the polymer vesicle co-loaded with two anti-tumor drugs has multiple advantages, including simple preparation, safety, high efficiency, a synergistic effect, etc., and is expected to greatly improve the treatment effects of malignant tumors, especially acute myeloid leukemia and acute lymphoblastic leukemia.
A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/475 - QuinolinesIsoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
A61P 35/02 - Antineoplastic agents specific for leukemia
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
30.
SINGLET OXYGEN CAPTURE OR RELEASE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF
2nn; the chemical formula of the singlet oxygen release material is [Cd(BP4VA-122nn, wherein BP4VA is 9,10-bis[(cis)-2-(pyridyl-4-)vinyl]anthracene, 4-NBA is a unit obtained after 4-nitrobenzoic acid loses hydrogen ions after reaction, and n is equal to 3,000-50,000. The materials have simple synthesis steps and high yield, and can be prepared in large amount; the materials can efficiently and quickly capture or release singlet oxygen; the singlet oxygen capture material can also be used as a fluorescent sensor for detecting oxygen, and has the advantages of simple operations, strong selectivity, high sensitivity, good cycle performance and good stability.
The present invention relates to the field of singlet oxygen technologies, and particularly to a singlet oxygen capturing or releasing material, and a preparation method and use thereof. The singlet oxygen capturing material according to the present invention has a chemical formula of [Cd(BP4VA)(4-NBA)2]n; and the singlet oxygen releasing material has a chemical formula of [Cd(BP4VA-1O2)(4-NBA)2]n, in which BP4VA is 9,10-bis[(cis)-2-(pyridin-4-yl)vinyl]anthracene, 4-NBA is a unit derived by removing a hydrogen ion from 4-nitrobenzoic acid after reaction, and n=3000-50000. The material has simple synthesis steps and high yield, and is capable of being prepared in large quantities. The material is capable of efficiently and rapidly capturing or releasing singlet oxygen. The singlet oxygen capturing material is also useful as a fluorescence sensor for detecting oxygen, with the advantages of simple operation, high selectivity, high sensitivity, and good recyclability and good stability.
The present invention belongs to the technical field of new use of medicines, and provides use of a medicine for reducing the iron content in brain in the preparation of a drug for treating and/or preventing neuropsychiatric diseases. The present invention provides a medicine/diet for reducing the iron content, which prevents the development of substance addiction behavior after administration, to prevent and treat substance addiction or dependence. The medicine is a hypoxia-inducible factor prolyl hydroxylase inhibitor or an iron chelating agent.
A61K 31/4418 - Non-condensed pyridinesHydrogenated derivatives thereof having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A61K 31/4412 - Non-condensed pyridinesHydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
The present invention discloses an equivalent source and drain region optimized field-effect transistor device for solving the problem of short-channel effects of a field-effect transistor in the prior art. The field-effect transistor device includes an active layer, and the active layer includes a source region, a drain region and a channel region located between the source region and the drain region; when the device is on, an effective channel and an equivalent source region and an equivalent drain region away from the effective channel at least in the thickness direction of the channel region are formed in the channel region, and the field-effect transistor device communicates the source region and the drain region via the effective channel and the equivalent source region and the equivalent drain region to contribute a working current, wherein the length of the equivalent source region is greater than that of the equivalent drain region.
H01L 29/08 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions with semiconductor regions connected to an electrode carrying current to be rectified, amplified, or switched and such electrode being part of a semiconductor device which comprises three or more electrodes
H01L 29/423 - Electrodes characterised by their shape, relative sizes or dispositions not carrying the current to be rectified, amplified or switched
The invention provides a spatiotemporal enhancement network based video action recognition method, including: S1. equally partitioning a video into T time periods, and randomly sampling one frame from each time period, to obtain an input sequence with T frames of image; S2. preprocessing the image sequence acquired in S1; S3. taking a tensor obtained in S2 as an input, inputting the tensor into a spatiotemporal enhancement network, by which spatial and temporal features are extracted; and S4. activating and normalizing the spatial and temporal features by softmax, averaging the normalized spatial and temporal features along a time dimension, obtaining classification scores of behaviors in videos through transformation, and then taking a label corresponding to the highest score as the classification result. A spatiotemporal enhancement module is embedded in a spatial network, so that better classification accuracy can be obtained by a deep learning based video behavior recognition system herein.
G06V 40/20 - Movements or behaviour, e.g. gesture recognition
G06T 5/20 - Image enhancement or restoration using local operators
G06V 10/62 - Extraction of image or video features relating to a temporal dimension, e.g. time-based feature extractionPattern tracking
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G06V 10/771 - Feature selection, e.g. selecting representative features from a multi-dimensional feature space
G06V 20/70 - Labelling scene content, e.g. deriving syntactic or semantic representations
35.
NANO-BORON DELIVERY AGENT, PREPARATION METHOD THEREFOR, AND USE THEREOF
A nano-boron delivery agent, a preparation method therefor, and the use thereof. The nano-boron delivery agent, h-10BN-PG nanoparticles, has the characteristics of convenience in preparation, no toxicity, good biocompatibility, high content of 10B, good dispersity and stability in a physiological solution, etc. The h-10BN-PG nanoparticles can inhibit protein adsorption and non-specific uptake of macrophages and have a good "stealth" feature; therefore, said nanoparticles are prevented from being rapidly removed by an MPS and a blood circulation time thereof is up to 8.5 hours. The h-10BN-PG nanoparticles can efficiently accumulate in CT26 tumor tissue by means of the EPR effect and can further undergo endocytosis by tumor cells; and the concentration of 10B in tumor can reach 8.8% ID/g or 102.1 ppm.
A method for preparing a cobalt sulfide/reduced graphite oxide composite includes: preparing a glycerol-cobalt precursor by taking a water-soluble cobalt salt, a micromolecular alcohol solvent, and glycerol as raw materials; mixing the glycerol-cobalt precursor with an alkali liquor to prepare a Co(OH)2 nanoflower; calcining the Co(OH)2 nanoflower to obtain a Co3O4 nanoflower; subjecting the Co3O4 nanoflower to a reaction with a water-soluble sulfur salt to obtain a COS nanoflower, and mixing the COS nanoflower with graphite oxide and carrying out a heat treatment to obtain the composite. The response characteristics of a gas sensor to NO2 gas are studied at room temperature, and the graphite is complexed with a transition metal sulfide with unique morphology to construct a unique heterostructure. While expanding the specific surface area to increase the number of adsorption sites, the heterostructure of a contact surface is used to greatly enhance the charge-transfer efficiency.
The present invention relates to the technical field of light-emitting devices, and relates to a light-emitting device having high hole injection efficiency and a manufacturing method therefor. The light-emitting device having high hole injection efficiency in the present invention comprises an anode, a hole injection layer, an interface functional layer, a hole transport layer, a light-emitting layer, an electron transport layer, and a cathode which are arranged in sequence. The material of the hole injection layer is a material having a work function greater than 5.1 eV; and the highest occupied molecular orbital (HOMO) energy level of the material of the interface functional layer is 0.2 eV or more higher than the HOMO energy level of the material of the hole transport layer, and an optical band gap of the material of the interface functional layer is greater than 2.6 eV. According to the light-emitting device of the present invention, an interface functional layer having a proper electron energy level and energy level disorder degree is introduced between a high-work-function electrode and a hole transport layer, such that Fermi level pinning between the electrode and an organic semiconductor is reduced or even eliminated, thereby effectively reducing hole injection barriers in the light-emitting device, suppressing accumulation of carriers at an interface, improving the hole injection efficiency, improving the light-emitting quantum efficiency and brightness, and prolonging the service life of the light-emitting device.
The invention provides an amino-substituted chromenoquinoline-based fluorescent marker, and preparation and use thereof. The amino group of an aromatic amine compound is subjected to a one-step cyclization reaction with two o-chloroformylcumarins, to obtain a series of nitrogen-containing heterocyclic compound. Such compounds have excellent fluorescence emission performance, and also have good photostability in various organic solvents. The problem of photostability of cyanine dyes is effectively solved, and these dyes are useful in marking various organelles at cellular level. The introduction of the nitrogen-containing heterocyclic ring improves the biocompatibility of the compound, thus laying a good foundation for use in organisms. Further, the raw materials used in such reactions are cheap and readily available, the steps of synthesizing the marker are simple and easy to operate, and the production cost is effectively reduced while not lowering the performance of the marker. Therefore, the present invention is of commercial value.
Disclosed are a biomass Schiff base, a biomass Schiff base polymer, a photo-thermal coating, and a preparation method. The biomass Schiff base is obtained by using 5-hydroxymethylfurfural and 1,10-diaminodecane as raw materials and reacting at 90-120°C for 0.5-3 hours. The biomass Schiff base polymer is obtained by curing epoxy resin with the biomass Schiff base. The photo-thermal coating is obtained by sequentially preparing a biomass Schiff base prepolymer-titanium nitride layer and a biomass Schiff base prepolymer-aluminum dihydrogen phosphate-fluorosilicone layer on a biomass Schiff base prepolymer film, and then curing. The coating prepared in the present invention has excellent wear resistance, especially can achieve self-repair, and in particular, can significantly prolong the icing time, thereby effectively solving the problems of poor wear resistance and icing resistance of an existing wear-resistant hydrophobic coating.
C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water theretoThawing or antifreeze materials for application to surfaces
40.
BIOORTHOGONAL BOND-CLEAVAGE REACTION SYSTEM, PRODRUG AND USE
22 can reach 103M-1s-1. By using the bioorthogonal bond-cleavage reaction, a corresponding smart fluorescent probe or prodrug containing tertiary amine functional groups is designed, is very stable under physiological conditions, and generates corresponding tertiary amine after undergoing a click reaction with an organosilicon boron reagent, thereby lighting up fluorescence or generating corresponding pharmacological activity.
C07D 311/16 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
C07C 291/02 - Compounds containing carbon and nitrogen and having functional groups not covered by groups containing nitrogen-oxide bonds
A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
The present invention provides an unsupervised fault diagnosis method for mechanical equipment based on an adversarial flow model, main steps including: data preprocessing, converting a mechanical vibration signal into a frequency domain signal, and normalizing the amplitude value of the signal into a range of [0, 1]; prior distribution designing: designing a mixture of Gaussian distribution with K subdistributions, wherein K is determined by the number of mechanical equipment status; model construction: constructing an unsupervised fault diagnosis model by combining an autoencoder, a flow model, and a classifier; model training: training the unsupervised fault diagnosis model by using various classes of status data, along with the designed prior distribution, preset training steps, loss functions, and an optimization algorithm; and fault diagnosis: inputting status data of mechanical equipment into the trained unsupervised fault diagnosis model to obtain a data clustering result and a fault diagnosis result.
Disclosed are a method and system for quantifying the dimensions of a lower space of a garment, belonging to the technical field of garment dimension quantification. The method comprises: according to a pre-acquired three-dimensional bare body model and clothed body model, constructing a garment/body cross-sectional graphic; according to the garment/body cross-sectional graphic, constructing an annular scale for measuring the thickness of an air layer at the bottom of the clothing; and according to the weight of the annular scale measurement area and the thickness of the air layer corresponding to the measurement area, calculating the thickness of the air layer at the bottom of the clothing, thereby quantifying the dimensions of the lower space of the garment. The method solves the problem that existing "cross-sectional point selection" methods are unable to reflect continuity between real clothing and a cross-sectional contour of the body, and the problem that an immense amount of discrete point set data is selected.
The present invention relates to a diffraction optical waveguide and a display module. The diffraction optical waveguide comprises a waveguide substrate, the waveguide substrate comprises a coupling-in area and a coupling-out area, the coupling-in area is used for coupling image light into the waveguide substrate, and the coupling-out area is used for coupling image light transmitted within the waveguide substrate out; the coupling-out area is provided with a grating structure, and the grating structure comprises a plurality of grating units; the direction from the coupling-in area to the coupling-out area is a first direction, the coupling-out area comprises at least two sub-areas which are sequentially provided in the first direction, a plurality of grating units are provided in each sub-area, and the density of a plurality of grating units in the sub-area close to the coupling-in area is smaller than the density of a plurality of grating units in the sub-area distant from the coupling-in area. By applying the diffraction optical waveguide provided by the technical solution of the present invention, the coupling-out efficiency in the eyebox range can be balanced, and the uniform pupil expansion by means of the diffraction optical waveguide is achieved, so that the brightness uniformity of different observation images in the eyebox range can be improved, thereby facilitating wide applications.
Disclosed in the present invention is an application of a metal sulfide piezoelectric material in piezoelectric catalytic reduction of CO2. The internal electric field generated by the piezoelectric material under external mechanical stimulation pushes electrons and holes to migrate in opposite directions, so that natural advantages are provided for separation and transmission of electron-hole pairs, but there is no report in the prior art that CO2 is reduced into C2+ products by means of piezoelectric catalysis. The present invention provides a metal sulfide piezoelectric nanomaterial and a preparation method therefor. The metal sulfide piezoelectric nanomaterial is used for piezoelectric catalytic reduction of CO2 for the first time, especially piezoelectric catalytic reduction of CO2 to obtain C2+ products so as to broaden the technical route of catalytic reduction of CO2.
C07C 51/353 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reactions not involving formation of carboxyl groups by isomerisationPreparation of carboxylic acids or their salts, halides, or anhydrides by reactions not involving formation of carboxyl groups by change of size of the carbon skeleton
A testing device and a comprehensive testing system based on Internet of things. The testing device comprises a base (1), a driving assembly (2), a cylinder (3), bearing bushes (4), a loading mount (5), and a loading device (6). The driving assembly (2) comprises a shaft assembly (21) and a driving source (22); the shaft assembly (21) comprises a shaft sleeve (211) and a main shaft (212); the shaft sleeve (211) is rotatably connected to the base (1); the main shaft (212) is rotatably arranged in the shaft sleeve (211); and one end of the main shaft (212) is connected to the driving source (22). The cylinder (3) is coaxially arranged on the shaft sleeve (211). A plurality of bearing bushes (4) are provided; the plurality of bearing bushes (4) are arranged in the cylinder (3) along the circumferential direction of the shaft sleeve (211); through holes are formed in the bearing bushes (4); the through holes are communicated with oil pipes; sensors are arranged in the oil pipes. The loading mount (5) comprises a base plate (51) and a bearing platform (52). When the loading device is arranged on the bearing platform (52), the load of the loading mount (5) and the main shaft (212) make axial relative movement, so that a loading disc (53) tightly presses the bearing bushes (4), thus simulating an operation process of a bearing. Moreover, the testing device can accurately measure and display an applied load force in real time, thereby guaranteeing the accuracy and visibility of the applied load force in a testing process, and by means of the oil pipes connected to the bearing bushes (4) and the sensors, multiple pieces of testing data of the bearing bushes (4) are accurately detected and the testing data is obtained. In addition, an Internet of things platform (8) is also comprised; the Internet of things platform (8) comprises a data collection system (81), a data processing system (82), and a data visualization system (83); the Internet of things platform (8) analyzes, processes and stores various data information collected by the sensors to implement flow, processing and summary analysis of information and data, thereby providing technical support for data processing and visualization and providing system support for intelligent monitoring of an operation state of the bearing, such that a user can remotely check and monitor the operation state and various operation data of the bearing bushes (4) in real time.
A fluorine-free carbon chain hydrophobic fabric, and its preparation method and application. A fabric is sequentially soaked in an alkali liquor and an acid liquor to obtain a pretreated fabric; the pretreated fabric then reacts with bromoacetyl bromide to obtain a treated fabric; the treated fabric then reacts with 1,2-bis(p-toluenesulfonyl) hydrazine to obtain a diazotized fabric; the diazotized fabric reacts with a diazoacetate monomer to obtain a fluorine-free carbon chain hydrophobic fabric; and the diazoacetate monomer is butyl diazoacetate, hexyl diazoacetate, octyl diazoacetate, dodecyl diazoacetate, tetradecyl diazoacetate or octadecyl diazoacetate. According to the scheme, diazoacetate is used as a monomer, and different fiber grafting modification processes are used, so as to form different structures on the fiber surface; and the comprehensive properties such as thermal stability, air permeability and breaking strength of the finished fabric are tested, the heat resistance and breaking strength of the finished fabric are reduced, and the air permeability is good.
D06M 13/372 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with non-macromolecular organic compoundsSuch treatment combined with mechanical treatment with compounds containing nitrogen containing etherified or esterified hydroxy groups
D06M 11/38 - Oxides or hydroxides of elements of Groups 1 or 11 of the Periodic Table
A carbene co-grafted modified fabric, a preparation method therefor, and an application thereof. Diazotized cotton fabric is sequentially subjected to a reaction with tert-butyl diazoacetate and octyl diazoacetate to obtain the carbene co-grafted modified fabric; or diazotized cotton fabric is sequentially subjected to a reaction with phenyl diazoacetate and octyl diazoacetate to obtain the carbene co-grafted modified fabric. Taking phenyl diazoacetate and tert-butyl diazoacetate as monomers, co-grafting into a cotton fabric is respectively performed with octyl diazoacetate carbene, a surface structure having low surface energy and good roughened morphology is constructed on a fiber surface, and excellent water repellency is consequently provided.
D06M 13/372 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with non-macromolecular organic compoundsSuch treatment combined with mechanical treatment with compounds containing nitrogen containing etherified or esterified hydroxy groups
A benzoxazine monomer, a composite material and a preparation method. A homogeneous reaction system of a biomass phenolic compound, a biomass amine compound and a paraformaldehyde undergoes a solvent-free Mannich reaction, so as to prepare a bio-based benzoxazine material. A four-layer structure composite coating formed by the bio-based benzoxazine material, HSi, P@mAlN and P@nAlN can effectively solves the problems of poor wear resistance and liquid puncture resistance of existing super-hydrophobic coatings, so as to obtain an anti/de-icing coating having good wear resistance, good liquid puncture resistance and excellent anti-icing performance and being more suitable for wind turbine blades in an icing environment. The composite coating exhibits remarkable mechanical and chemical durability, and the outstanding mechanical and chemical durability prolongs the service life of the coating, thereby expanding the practical applications thereof.
C07D 265/16 - 1,3-OxazinesHydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with only hydrogen or carbon atoms directly attached in positions 2 and 4
C09K 5/14 - Solid materials, e.g. powdery or granular
C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water theretoThawing or antifreeze materials for application to surfaces
C09D 179/04 - Polycondensates having nitrogen-containing heterocyclic rings in the main chainPolyhydrazidesPolyamide acids or similar polyimide precursors
The invention provides a high-resolution QD pixelated light-emitting film and method for preparing same. The method includes: spin-coating a photoresist on a base; drying and exposing the base; coating a developer at a preset position on the base to obtain a photoresist pattern layer; depositing an insulating layer on the photoresist pattern layer by using silane; removing a photoresist pattern in the insulating layer; spin-coating a polyethylenimine solution on the insulating layer to obtain a PEI layer; and dropping a QD solution on the PEI layer to deposit a QD layer. The hydrophobicity of silane is used to implement dewetting to implement QD pixilation. A PEI solution is spontaneously deposited at the position of a photoresist pattern. Further, the QD solution is adsorbed into the PEI solution to obtain a high-resolution QD pixelated light-emitting film, thereby improving the film forming quality, and passivating surface defects of a QD layer.
H10K 71/20 - Changing the shape of the active layer in the devices, e.g. patterning
H10K 71/12 - Deposition of organic active material using liquid deposition, e.g. spin coating
H10K 50/115 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising active inorganic nanostructures, e.g. luminescent quantum dots
The present invention provides a method for synthesizing a bifunctional pure organic photocatalytic material with the capabilities of fast adsorption and efficient degradation. By means of reasonably introducing a perylene imide group into an amphiphilic block copolymer, a micelle for treating contaminants in water is formed by self-assembly. The present invention features the advantages in that the micelle formed by self-assembly of the perylene-based amphiphilic block polymer is uniform in size, exhibits ultra-high adsorption capacity on bisphenol A, and can rapidly reach a stable adsorption equilibrium at various concentrations or temperatures. The micelle also demonstrates, in a mixed phenol solution, significant recognition selectivity and good affinity for bisphenol A. In addition, the micelle has rapid degradation efficiency on bisphenol A. The present invention provides a new design concept for the advanced treatment of wastewater by using a metal-free organic material.
C08J 3/07 - Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from polymer solutions
Disclosed is a use of compound 2-bromopalmitate (2-BP) in treatment of cerebrovascular diseases. 2-BP can obviously reduce the volume of acute cerebral infarction in mice with focal ischemic stroke, significantly improve the neurobehavioral symptoms thereof, inhibit the reactive astrogliosis, and have a cerebral neuroprotective effect.
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
The present application discloses a head-up display module and a vehicle. The head-up display module comprises: a first waveguide module, a second waveguide module, and a reflecting layer; the first waveguide module and the second waveguide module are arranged in parallel in a staggered manner; first light out-coupled by the first waveguide module forms a first light area; second light out-coupled by the second waveguide module forms a second light area, wherein the directions of the first light and the second light are the same, and the first light area and the second light area are seamlessly spliced or partially overlapped; and the reflecting layer is located at a preset position in the opposite direction of the first light and the second light, and the reflecting layer is used for reflecting, to the first light area and the second light area, the light emitted to the reflecting layer. According to the head-up display module and the vehicle provided by the present application, two waveguide modules having relatively small sizes can be used in combination, such that the characteristics of small size, lightness and thinness of a diffraction waveguide scheme can be continued, the display performance of a large field of view can be supported, and the manufacturing difficulty can be reduced.
The present invention relates to a polymer microsphere loaded with active metal particles, and a preparation method and application therefor, belonging to the technical field of tumor embolism treatment. The polymer microsphere loaded with active metal particles comprises a polymer microsphere skeleton and active metal particles distributed in the polymer microsphere skeleton. In the invention, the target microsphere is prepared mainly by using a reversed-phase microemulsion method. The polymer microsphere loaded with active metal particles is used for arterial tumor embolization, and can embolize a tumor blood vessel, block nutrient supply of the tumor part, slowly and continuously release hydroxide in situ to regulate the weakly acidic tumor microenvironment, release hydrogen to activate immune response, initiate hydrogen treatment, and amplify embolism treatment. The solution shows a better combined treatment effect compared with using only polymer microsphere embolism treatment.
Disclosed in the present invention are a cleaning solution for a high-yield-stress ceramic material 3D printing blank, a preparation method therefor and the use thereof. The cleaning solution is composed of a main cleaning agent and an auxiliary cleaning agent, wherein the main cleaning agent is isobornyl acrylate (IBOA), N-acryloylmorpholine (ACMO), hydroxyethyl methacrylate (HEMA), 3-ethyl-3-oxetanemethanol (EHO), or a combination thereof. According to the cleaning solution of the present invention, ultrasonic cleaning or pressure spraying is used, such that the problem of cleaning the high-yield-stress ceramic material 3D printing blank is effectively solved. The present invention is not only simple to clean, but also has a good effect and excellent efficiency.
B08B 3/02 - Cleaning by the force of jets or sprays
B08B 3/08 - Cleaning involving contact with liquid the liquid having chemical or dissolving effect
B08B 3/12 - Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
B28B 1/00 - Producing shaped articles from the material
B28B 11/22 - Apparatus or processes for treating or working the shaped articles for cleaning
B33Y 40/20 - Post-treatment, e.g. curing, coating or polishing
A super-hydrophobic fabric, and a preparation method therefor and the use thereof. A super-hydrophobic function is achieved by means of cooperation between modified cellulose nanocrystals and an organosilicon waterproof agent, the hydrophobic performance of the fabric is particularly good, and the preparation method is simple. The method comprises: first modifying cellulose nanocrystals (CNCs) by using heptadecafluorodecyl trimethoxysilane, and dispersing the modified cellulose nanocrystals in a solution containing a hydroxyl silicone oil and a hydrogen-based silicone oil; and after impregnating a cotton fabric, taking same out and then drying same, so as to obtain a super-hydrophobic fabric, wherein a surface super-hydrophobic layer is composed of modified cellulose nanocrystals in cooperation with organosilicon, and the fabric finished by a silicone oil containing modified CNCs shows perfect super-hydrophobicity, the contact angle reaching 169.3° and the rolling angle being 4.9±0.1°. The finishing process of the fabric is completed at room temperature, the production and preparation process is simple, the reaction conditions are mild, operation thereof is safe, and scaled-up production can be easily realized.
D06M 15/643 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds containing silicon in the main chain
D06M 13/513 - Compounds with at least one carbon-metal or carbon-boron, carbon-silicon, carbon-selenium, or carbon-tellurium bond with at least one carbon-silicon bond
The present application relates to the technical field of display. In particular, disclosed are a naked-eye three-dimensional (3D) display apparatus and method, and a readable storage medium. The apparatus comprises a polarization backlight module and a polarization modulation plate, wherein the polarization backlight module is used for outputting light with an adjustable polarization direction; the polarization modulation plate is arranged in the light-emergent direction of the polarization backlight module; and the polarization modulation plate comprises several pixel units, each pixel unit comprises several sub-pixels, the sub-pixels at the same relative position in all the pixel units form a pixel group, one pixel group correspondingly transmits light in the same polarization direction to the same viewpoint, and different pixel groups correspond to different viewpoints. When the polarization backlight module sequentially outputs light in different polarization directions, different groups of sub-pixels can sequentially converge the light in different polarization directions to different viewpoints; and when human eyes receive different disparity map information, fusion can be performed to achieve a 3D experience, and viewpoints come from different sub-pixels of each pixel unit without the need for reusing pixels, such that the whole display resolution is not affected.
G02B 30/25 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the stereoscopic type using polarisation techniques
G02B 30/50 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images the image being built up from image elements distributed over a 3D volume, e.g. voxels
H04N 13/302 - Image reproducers for viewing without the aid of special glasses, i.e. using autostereoscopic displays
Disclosed in the present invention are a bio-based epoxy monomer, a medium-temperature cured epoxy resin system, and a preparation method. The preparation method specifically comprises: preparing a tetrahydroxy monomer by taking protocatechuic aldehyde and erythritol as raw materials; then, preparing the bio-based epoxy monomer by taking the tetrahydroxy monomer and epoxy chloropropane as raw materials; uniformly melting and mixing the bio-based epoxy monomer and a catalyst, then adding an anhydride compound at 60-80ºC, and pre-polymerizing the mixture to obtain a medium-temperature curable epoxy resin system; and then carrying out medium-temperature curing to obtain a high-performance degradable multifunctional epoxy resin. Compared with an existing biomass epoxy monomer or even a traditional commercial bisphenol A epoxy resin, the resin system of the present invention has the advantages of a low curing temperature and a short curing time, and can effectively save on energy consumption; and the comprehensive mechanical properties and thermal properties of the cured system are obviously superior to those of an existing reported biomass epoxy system which contains a dynamic reversible bond and has mild degradation characteristics, and are better than those of a commercial bisphenol A epoxy resin system cured with the same curing agent.
The present invention provides a B/N organic electroluminescent material and its preparation method and use, as well as the corresponding organic light-emitting device. The B/N organic electroluminescent materials DBTN-1 and DBTN-2 in the present invention show narrowband green emission both in dilute solution and doped film, with extremely high photoluminescence quantum yields and efficient thermally activated delayed fluorescence feature. In particular, the organic light-emitting devices based on the above fluorescent dye exhibit ultra-pure green electroluminescence with high efficiencies and high color purity, which can be applied to usages such as ultra-high definition display technology.
Disclosed is a line spectral confocal three-dimensional measurement system and method using a linear variable filter. The system includes a light source module for providing light radiation, a spectral confocal module, and a signal acquisition module. The spectral confocal module includes a first linear variable filter, a first imaging lens group, a second imaging lens group, and a second linear variable filter. The first linear variable filter is configured to separate the light radiation according to different wavelengths. The first imaging lens group is configured to focus the light radiation with different wavelengths at different heights along a normal line of a surface of a measured object. The second imaging lens group is configured to guide the focused light radiation to the second linear variable filter, and the light radiation at a corresponding position of the first linear variable filter passes through the second linear variable filter.
22, and LiH. It is disclosed in the present invention for the first time that o-diiodobenzene can be used to rapidly produce biphenylene at room temperature under the action of an alkali metal hydride such as sodium hydride. The reaction is green and efficient and has a high atom conversion rate, no transition metal catalysis is required, and the raw material o-diiodobenzene is cheap and easily available; an experiment is easy to operate, and a high yield can still be obtained when the experiment is scaled up; a reaction product is difficult to obtain in one step by other methods; and the product has important significance in organic synthesis, medicinal chemistry and materials chemistry.
C07C 1/28 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only halogen atoms as hetero atoms by ring closure
61.
IMAGE SEGMENTATION METHOD, ELECTRONIC DEVICE, AND COMPUTER-READABLE STORAGE MEDIUM
Disclosed are an image segmentation method, an electronic device, and a computer-readable storage medium. The method comprises: S1, setting an initial contour line in a target image, and using an initial level set function to represent the initial contour line; S2, updating and iterating the initial level set function; and S3, taking a level set function obtained from the last iteration as a segmentation curve of the target image. According to the image segmentation method of the present invention, a length item in a traditional active contour model is replaced with a mean filter, which is configured for smoothing the segmentation curve; a distance rule item in the traditional active contour model is replaced with an activation function, which is configured for achieving the rule that the level set function always keeps values on the contour line and inside the contour line negative and values outside the contour line positive in an iteration process. The image segmentation method of the present invention has an ideal segmentation effect on an image with an uneven grayscale, and has advantages in both segmentation speed and segmentation accuracy.
Disclosed in the present invention is a method for on-site typing detection of norovirus types GI and GII. The method comprises the following steps: in the presence of a primer, performing dual RT-RPA reaction on a template, then adding the amplification products after the reaction into CRISPR/Cas12a detection systems for norovirus types GI and GII, respectively, and performing fluorescence analysis to complete the on-site typing detection of norovirus types GI and GII. In the present invention, each subtype of norovirus GI and GII is covered, and there is no cross reaction with common gastroenteritis viruses such as rotavirus and enteric adenovirus, and the norovirus genotypes GI and GII can be effectively distinguished without an off-target phenomenon. The limit of detection for norovirus genotypes GI and GII are respectively 10 2 copies/µL and 1 copies/µL. The whole detection process can be completed within 35 min at the constant temperature of 37°C. The on-site detection can be performed directly using a UV flashlight without the requirements for laboratory instruments and professional operation.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
The present invention discloses a field effect transistor device for improving the problem of the short-channel effect of a field effect transistor in the prior art, comprising: an active layer, comprising a source region, a drain region, and a channel region located between the source region and the drain region; a gate provided around the channel region; and a gate insulating layer provided between the gate and the channel region; wherein when a device is turned on, an effective channel, and an equivalent source and/or equivalent drain away from the effective channel are formed in the channel region, and the field effect transistor device connects the source region and the drain region through the effective channel, and the equivalent source and/or equivalent drain to contribute an operating current.
The invention relates to a multi-source wireless optical communication spectrum sensing system, including: a transmit end, configured to transmit an optical signal, the transmit end including multiple LEDs; and a secondary user terminal, configured to: receive the optical signal transmitted by the transmit end, convert the optical signal into an electrical signal, filter out a direct current component in the electrical signal to obtain a filtered electrical signal, sample the electrical signal to obtain sampling data and a corresponding sampling quantity, perform channel estimation based on the sampling quantity and acquired location data of the secondary user terminal to obtain a channel matrix, calculate a detection metric M and a decision threshold K based on the channel matrix, the sampling data, and the sampling quantity, and determine, based on a value relationship between M and K, whether a channel is occupied by a primary user.
A method for improving the strength of raw silk. By adjusting the temperature in a mounting process, the performance of cocoon silk is improved, the difference in the relative strength of different partitions of the cocoon silk is reduced, and the cohesive force of produced 20/22D raw silk reaches 98 times and the strength thereof reaches 96 cN. According to the physiological characteristics of silkworms in a spinning process, the strength of the raw silk can be improved by controlling temperature conditions; and the method is characterized in that it is convenient to operate, low in terms of cost and easy to promote and apply.
Provided in the present invention are an imprint apparatus and an imprint method. The imprint apparatus comprises a mold, a resist application device and an imprint assembly, wherein the imprint assembly comprises an alignment adjusting device, a guide roller, a pressure roller and a translation roller set. By moving the translation roller set, a film tape is tensioned on one side of the mold such that a first pattern on the mold is initially aligned with a second pattern on the film tape, and the relative positions of the mold and the film tape are then precisely adjusted by means of the alignment adjusting device, thus achieving precise alignment of the first pattern with the second pattern; then, the distance between the mold and the film tape is reduced such that the film tape, a resist layer and the first pattern come into contact, and the film tape is roll-pressed by using the pressure roller to achieve a tight fit between the film tape, the resist layer and the mold; and a film is removed by moving the translation roller set in the opposite direction. The present invention can achieve micron-grade and high-precision UV light transfer for multilayer patterns on a continuous roll.
G03F 7/00 - Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfacesMaterials therefor, e.g. comprising photoresistsApparatus specially adapted therefor
67.
SHORTEST PATH SOLVING METHOD AND SYSTEM FOR METRO NETWORK NODE
Provided in the present invention are a shortest path solving method and system for a metro network node. The method comprises: S1, acquiring station data and road section data of a metro network; according to the station data and the road section data, constructing a completely directed metro network model G (N, A) by taking stations as directed nodes and taking road sections as directed arcs; initializing parameters of the metro network model G (N, A), and obtaining all OD travels on the basis of the metro network model G (N, A); calculating theoretical shortest paths of the OD travels, and correcting the OD travels according to a set correction rule; and calculating and recording actual shortest path matrices and shortest path target values of all the OD travels. The present invention solves the problem of an error path being output from an undirected or partially directed network due to ignoring a path weight between transfer nodes, can also realize the accurate allocation of a passenger flow, thereby facilitating the travel of passengers, and solves the problem of it being impossible to perform accurate prognosis when situations such as a one-way fault occur in existing networks.
Disclosed in the present invention are a chiral azobenzene polymer crosslinked thin film and preparation method therefor and application thereof. The present invention relates to a novel super-molecular chiral construction and chiral immobilization method based on an achiral side chain type azobenzene polymer thin film. According to the present invention, limonene steam is utilized to perform chiral induction on a polymer thin film at a high temperature, and then formaldehyde steam is utilized to perform acetal reaction with hydroxyl in an acidic environment to achieve crosslinking; and then differences in the stability of the super-molecular chirality of the polymer thin film before and after crosslinking is studied under the conditions of light, heat and good solvent dissolution, and the self-repairing properties of microcosmic helical chirality is researched. The crosslinked thin film prepared by the present invention has good chiral properties, and excellent solvent resistance, heat resistance, and self-repairing properties.
A biomass epoxy monomer, a biomass self-curing epoxy resin and a preparation method therefor. Biomass tyramine and diphenolic acid are used as raw materials and undergo a heating reaction to obtain a phenolic compound; the phenolic compound and epichlorohydrin undergo a heating reaction to obtain an amide bond-containing biomass epoxy monomer; and the amide bond-containing biomass epoxy monomer is cured to obtain a biomass epoxy resin. Compared with the prior art, the epoxy resin has excellent thermal properties, high flexural modulus and strength, and high impact strength.
C07D 301/28 - Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms by reaction with hydroxyl radicals
C08G 59/32 - Epoxy compounds containing three or more epoxy groups
C07D 303/27 - Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having all hydroxyl radicals etherified with oxirane containing compounds
C08G 59/06 - Polycondensates containing more than one epoxy group per molecule of polyhydroxy compounds with epihalohydrins or precursors thereof of polyhydric phenols
70.
HYPERSPECTRAL IMAGE AND LASER RADAR IMAGE FUSION METHOD AND SYSTEM FOR FIELD OF REMOTE SENSING
Provided in the present invention are a hyperspectral image and laser radar image fusion method and system for the field of remote sensing. The method comprises: selecting a hyperspectral image I and a laser radar image L; obtaining a shadow mask M according to I; performing shape change and logarithmic transformation on I and L, so as to obtain a hyperspectral image I~ and a laser radar image L~; constructing a weight matrix on the basis of I~, L~ and M; establishing an optimization function E for optimizing an intrinsic reflection image R~ and an intrinsic irradiation image S~, and initializing R~ and S~; calculating partial derivatives of the optimization function E with respect to R~ and S~, performing iterative updating on R~ and S~ until a set stop condition is met and then stopping updating; and taking a finally obtained R~ and a finally obtained S~ as an optimal R~ and an optimal S~, and processing the optimal R~ and the optimal S~, so as to obtain a final fused image K. In the present invention, important discrimination information in a hyperspectral image and important discrimination information in a laser radar image are efficiently extracted and fully fused, thereby improving the classification capability and classification precision with respect to multi-source remote sensing images.
An optical element storage device and mechanism. The optical element storage device comprises a base (1), a first recess (11) being formed on the surface of the base (1), a second recess (12) being formed in the first recess (11), a boss (13) being provided along the inner wall of the second recess (12), and an optical element to be stored being placed on the boss (13); and a cover unit, comprising an upper cover (2) and a pressing block (3), a third recess (21) being formed in the upper cover (2), a fourth recess (22) being formed in the third recess (21), the pressing block (3) being provided in the fourth recess (22), the pressing block (3) being movably connected to the fourth recess (22), the area of the projection of the pressing block (3) on the base (1) being larger than the sectional area of the first recess (11), and the upper cover (2) being detachably connected to the base (1). The optical element storage device has a simple structure, is convenient to carry, and can stably store and transport an optical element; moreover, energy dissipation and shock absorption can be achieved, such that the optical element is protected to the maximum extent, and the damage to the surface of the optical element is avoided.
B65D 85/38 - Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure for delicate optical, measuring, calculating or control apparatus
B65D 25/10 - Devices to locate articles in containers
B65D 81/05 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
72.
METHOD FOR PREPARING HALOGENATED COMPOUND FROM METAL HALIDE SALT ON BASIS OF MOBILE PHASE
Disclosed is a method for preparing a halogenated compound from a metal halide salt on the basis of a mobile phase. The method comprises: converting an aromatic hydrocarbon, alkane or nitrile compound into a halogenated compound by means of a cheap metal halide salt and a photocatalyst under illumination. The method uses a cheap and safe halide salt as a halogen source, does not introduce additional elemental halogen or an additional oxidant, can implement a reaction at normal temperature and normal pressure, is high in terms of selectivity and friendly to environment, and can be used for replacing an existing synthesis reaction system for halogenated compounds. A mobile phase device is used to replace a tank reactor, such that operation is easy and convenient, the price is low, the substrate adaptability is high, the continuous synthesis of halogenated compounds can be achieved, and the method is suitable for industrial large-scale production.
C07C 17/10 - Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
C07C 17/14 - Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
C07C 22/04 - Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings containing six-membered aromatic rings
C07C 23/08 - Monocyclic halogenated hydrocarbons with a five-membered ring
C07C 23/10 - Monocyclic halogenated hydrocarbons with a six-membered ring
C07C 255/10 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and halogen atoms, or nitro or nitroso groups, bound to the same acyclic carbon skeleton
A continuous flow test method and apparatus for a micro/nano material, for use in quantitative research on dissolution and release behaviors of a micro/nano material to obtain key information related to the biological/environmental safety and the degradation fate of the micro/nano material. The apparatus comprises a pressure system, a liquid storage system, a constant temperature system, a dissolution system, a collection system, and a flow rate control system. The liquid storage system, the dissolution system, the flow rate control system, and the collection system are successively connected by means of a pipeline to form a liquid flow path. The pressure system of the apparatus is easy to operate and can achieve stable pressure drive within the range of 100 kPa. A pressure source is used, which can collaboratively work with the flow rate control system to maintain the same flow rate for multiple sets of parallel tests, performance stability within a wider pressure range can be achieved, and a unique funnel-shaped inner cavity can achieve the minimization of a dead volume. Test results prove that the method greatly improves the test stability and the repeatability of experimental results.
G01N 11/04 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
Provided are a regulatory T cell modified by a PD-1-targeting chimeric antigen receptor, a preparation method therefor, and an application thereof. In order to solve the present problems of peripheral-blood Treg cell separation and purification, amplification difficulty, non-antigen specificity, etc., PD-1 on the surface of a T cell is used as a target point, and an extracellular region of a CAR molecule is designed as a PD-1 ligand, namely an extracellular domain of PD-L1 or a single-chain antibody constructed by an activated antibody of PD-1. In addition, a FOXP3 transcription factor and a CAR fusion protein are co-expressed, and are directly induced and differentiated into CAR-Treg from inside the peripheral-blood T cells, thereby solving the problem of low Treg content in peripheral-blood sources. An intracellular inducible antigen-specific CAR-Treg can be prepared, achieving inhibitory-effect T cell proliferation and killing functions, thereby achieving the purposes of improving aGVHD and controlling autoimmune diseases.
An optical element storage device includes: a base provided with a first groove on the surface, a second groove being provided in the first groove, a boss being provided along an inner wall of the second groove, the optical element to be stored being placed on the boss; and a cover body unit including a top cover and a pressing block, a third groove being provided in the top cover, a fourth groove being provided in the third groove, the pressing block being provided in the fourth groove, the pressing block being movably connected with the fourth groove, the projected area of the pressing block on the base being larger than the sectional area of the first groove, the top cover being detachably connected with the base. The storage device has a simple structure and is easy to be carried, and can store and transport the optical element stably.
B65D 85/38 - Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure for delicate optical, measuring, calculating or control apparatus
B65D 1/36 - Trays or like shallow containers with moulded compartments or partitions
B65D 81/02 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
76.
METHOD FOR PREPARING 2-IODO ARYL ETHER UNDER THE ACTION OF ALKALI METAL HYDRIDE
Disclosed in the present invention is a method for preparing 2-iodo aryl ether under the action of alkali metal hydride: adding alkali metal hydride and phenol to a solvent, then adding 1,2-diiodoarene, and reacting at 0-100° C. to obtain a 2-iodo aryl ether product. The coupling process of the present invention does not require the addition of a transition metal catalyst, and does not cause metal contamination to the product; the method of the present invention can be performed at room temperature and has high functional group compatibility, and solves the problem that existing metal-catalysed coupling to aryl ether reactions need to be performed at a relatively high temperature.
The present invention relates to a method for preparing a carboxylic acid ester compound. Under the catalysis of nitrite, a carboxylic acid reacts with an alcohol in air so as to obtain an ester compound; and the alcohol is ethanol, propanol or trifluoroethanol. The present invention has the advantages such as mild reaction conditions, rich source of raw materials, wide universality of reaction substrates, and simple operation, and can modify a series of carboxylic acids having medicinal properties and aliphatic carboxylic acids such as biologically active amino acids.
C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
78.
Long-acting antibacterial anti-stenosis functional urethral stent and preparation method thereof
NANTONG TEXTILE & SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (China)
SOOCHOW UNIVERSITY (China)
Inventor
Li, Gang
Li, Lu
Li, Feng
Duan, Lirong
Abstract
A long-acting antibacterial anti-stenosis functional urethral stent and preparation method thereof is provided; the urethral stent is a tubular structure consisting of three layers: inner, middle and outer layers; the middle layer is a fabric tube; the outer layer is a silk fibroin film carrying anti-stenosis drugs; the inner layer is an antibacterial antifouling coating, consisting of chitosan-nanosilica arrays, villi, microvilli and antibacterial drugs; the preparation method includes: after making yarns into the fabric tube by textile molding, preparing the antibacterial and anti-fouling coating on the inner surface, and the silk fibroin film carrying anti-stenosis drugs on the outer surface respectively, to obtain the long-acting antibacterial anti-stenosis functional urethral stent. The method is simple, and the prepared urethral stent has a smooth surface and good biocompatibility, which has excellent properties such as radial compression force, circumferential expansion force, resistance to bending and torsion and elastic recovery.
The invention relates to the field of drugs, and particularly to use of a small molecule compound and lenalidomide in the preparation of a drug for treating multiple myeloma. How to promote the degradation of a transcription factor IKZF1 necessary for the proliferation of a downstream substrate, namely myeloma cells, is a difficulty in the treatment of multiple myeloma. According to the present invention, the combined use of the small molecule compound 2-BP and lenalidomide in the treatment of multiple myeloma obviously reduces the IKZF1 protein level, and the proliferation of the multiple myeloma cells is inhibited after the multiple myeloma cells are treated by the small molecule compound 2-BP in combination with lenalidomide.
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A method for estimating a leakage inductance parameter of a high-frequency transformer of a dual active bridge (DAB) converter. The method comprises: performing sampling on an output of a DAB converter, so as to obtain the present current value and the present voltage value; performing calculation according to the present current value, so as to obtain an average current value; according to the average current value, the present current value and the current voltage value, calculating leakage inductance of a transformer by using a gradient descent method; predicting an output voltage according to the leakage inductance of the transformer and the average current value; and calculating a phase shift angle to be subjected to evaluation, selecting a phase shift angle according to the principle of making a cost function minimum, and controlling the DAB converter. The method greatly reduces output ripples of a DAB direct current-direct current converter under model predictive control, can accurately and quickly track a reference output voltage, and has good steady-state performance and dynamic performance; and the complexity of code parameters is simplified, modular implementation of codes is facilitated, and reuse and maintenance of the codes are facilitated, such that the cost can be reduced to a certain extent.
A group delegation computing method includes: executing a key generation algorithm to obtain various types of keys; executing a member joining algorithm to implement a member joining function, combining customers with the same need into a group, and delegating a blinded delegation function to a cloud server; executing a question generation algorithm to generate a group signature and delegating a computing task to the cloud server; executing a signature verification algorithm to output a verification result; executing a computing algorithm only when a signature is valid to obtain a computing result and a correctness proof; executing a blind verification algorithm to verify whether the result; if the result is correct, executing a recovery algorithm; executing a member revocation algorithm to perform a member revocation function; and when there is a dispute over the delegation computing, executing an open algorithm to trace an identity of a specific member.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
82.
PHOTOVOLTAIC CELL ELECTRODE AND MANUFACTURING METHOD AND MANUFACTURING APPARATUS THEREFOR, AND USE
The present invention relates to a photovoltaic cell electrode and a manufacturing method and manufacturing apparatus therefor, and a use. The manufacturing apparatus for the photovoltaic cell electrode comprises a laser source, a collimated light beam generating unit and a light beam focusing unit; the collimated light beam generating unit is located on a light exit side of the laser source, and is used for converting a laser beam emitted by the laser source into a collimated light beam and projecting the collimated light beam to the light beam focusing unit; the light beam focusing unit is located on a light exit side of the collimated light beam generating unit, and is used for focusing the collimated light beam to a cell to be photoetched. When the manufacturing apparatus of the present invention is used for manufacturing a photovoltaic cell electrode, a plurality of spatial light modulators, projection optical systems and illumination optical systems are not required, so that the apparatus development cost is reduced exponentially; data processing and multi-optical-path overlapping alignment are not required, and therefore, manufacturing reliability and efficiency are improved; the present invention can achieve the photoetching of electrode pattern trenches having a high depth-to-width ratio, for example, a depth-to-width ratio of 0.3 to 2, wherein the line width is 3 μm to 20 μm and the depth is 1 μm to 20 μm, thereby obtaining a high-quality photovoltaic cell electrode.
A benzothiazinone derivative substituted with trifluoromethyl at 6-position, and a preparation method therefor and the use thereof. A series of compounds are obtained by means of changing the benzene ring of the benzothiazinone backbone, especially by means of changing a substituent thereof. Compared with other benzothiazinone derivatives, the benzothiazinone derivative substituted with trifluoromethyl at 6-position is more stable with regard to hepatic microsomal enzymes, and has longer metabolic half-life T1/2 and better water solubility.
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61P 31/06 - Antibacterial agents for tuberculosis
84.
METHOD FOR PREPARING TIN OXIDE NANOPARTICLES DISPERSED IN ALCOHOL SOLVENT, AND USE THEREOF
The present invention relates to the technical field of nano-materials and provides a method for preparing tin oxide (SnO2) nanoparticles dispersed in an alcohol solvent, and use thereof. The preparation method includes: (1) dissolving tin chloride and a base in an ethanol solution, reacting with heating at a constant temperature, subjecting the reaction product to solid-liquid separation, collecting the solid phase, and dissolving the solid phase in an alcohol solvent, to obtain a tin oxide-alcohol dispersion; and (2) adding a quaternary ammonium base to the tin oxide-alcohol dispersion obtained in Step (1), and reacting with stirring, to obtain the tin oxide nanoparticles. The tin oxide nanoparticles of the present invention provide a new approach to the improvement of the stability of optoelectronic devices, and broaden the scope of SnO2 application, thus having important practical significance.
12344 is selected from an ester group. The alkylzinc reagent is applied to a bifunctional reaction of olefin, and the alkyl-substituted alkyl difluoro reagent is applied in click chemistry.
C07C 53/126 - Acids containing more than four carbon atoms
C07C 51/41 - Preparation of salts of carboxylic acids by conversion of the acids or their salts into salts with the same carboxylic acid part
C07C 67/347 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisationPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
C07C 69/75 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring
C07C 69/65 - Halogen-containing esters of unsaturated acids
C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
The present invention relates to the technical field of medicines. Disclosed is a use of recombinant human Matrilin-3 (rhMatrilin-3) protein in the preparation of a drug for treating cerebrovascular diseases. Matrilin-3 protein refers to rhMatrilin-3 protein. According to the technical solution of the present invention, the blood-brain barrier permeability of rats with focal cerebral ischemia can be remarkably reduced, the cerebral atrophy volume of the rats in the recovery period of ischemic stroke is reduced, and the neurological symptoms of the rats are remarkably mitigated. In addition, according to the present technical solution, the death of neurons and astrocytes induced by the ischemic stroke can be reduced; moreover, inflammatory response after ischemic brain injury is inhibited, and a cranial nerve protection effect is achieved.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
87.
DIAGNOSIS AND TREATMENT INTEGRATED NUCLEIC ACID ANCHORING-TYPE FLUORESCENT PROBE AND PREPARATION METHOD THEREFOR AND USE THEREOF
Disclosed are a diagnosis and treatment integrated nucleic acid anchoring-type fluorescent probe and a preparation method therefor and a use thereof. The fluorescent probe can spontaneously generate singlet oxygen and undergo a crosslinking reaction with RNA in cells under the mediation of the singlet oxygen, thereby achieving long-window-period imaging of tumor tissues; additionally, after RNA crosslinking, mitochondrial function damage is caused and further induces severe apoptosis in tumor cells, thereby achieving diagnosis and treatment integration of tumors.
Disclosed in the present invention are a layered metal oxide/amine composite material, and a preparation method therefor and an application thereof in a magnesium-ion battery. An anionic metal oxide solution and an amine compound solution are mixed to obtain a precipitate; and then the precipitate is dried to obtain a layered metal oxide/amine composite material. By designing a layered metal oxide/amine compound composite material, adjusting the stacking structure of the material, and using the material as a positive electrode active material for a magnesium-ion battery, the problem of slow diffusion of highly charged magnesium ions in a material lattice is solved, the stability of the layered structure is maintained, and the high electrochemical activity of the metal oxide material is maximized.
A resistance valve, comprising: an inner cylinder (2), which can deform outwards in a radial direction, wherein an outer wall of the inner cylinder (2) is provided with a semi-elliptical outer helical groove (22), and the inner cylinder (2) is internally provided with an inclined deformation chute (21); a slider (5), which slides in the inner cylinder (2) in the extension direction of the deformation chute (21), wherein an inclined face (51) of the slider (5) abuts against the deformation chute (21), and the inner cylinder (2) is pushed by means of the slider (5) to deform outwards in the radial direction; a rotary shaft (6), which is in threaded connection with the slider (5), wherein by rotating the rotary shaft (6), the slider (5) is driven to slide in the axial extension direction of the rotary shaft (6); and an outer cylinder (3), which is sleeved outside the inner cylinder (2), wherein an inner wall of the outer cylinder (3) is provided with a semi-elliptical inner helical groove (31), and the inner helical groove (31) fits with the outer helical groove (22) to form a multi-layer helical accommodating space (8) for a plastic tube. The holding length of the plastic tube is increased by means of helical winding, and appropriate resistance to the plastic tube is provided by means of radial deformation of the cylinder, thereby providing back pressure required for the operation of a pump connected to the plastic tube, and reducing the effect on a flowing medium therein.
A multi-optical-head parallel fast photolithography system, comprising: a photomask (1), a substrate (2) and a plurality of optical heads (3), wherein each optical head (3) comprises a photolithography illumination module (31) and a mask projection optical module (32); the photolithography illumination module (31), the photomask (1), the mask projection optical module (32) and the substrate (2) are arranged in sequence along an optical path; the mask projection optical module (32) is a reverse imaging module; and a projection light spot is a magnified upside-down real image of an illumination light spot of the photomask (1). By means of the spatial layout of a plurality of optical heads (3) being placed in a staggered manner and the matching of optical projection imaging sizes in the entire system, the optical heads (3) can perform scanning exposure in parallel, such that the problem of a single optical head (3) having a limited field of view is solved, and in principle, the width is not limited and the optical path implementation feasibility is high. A large-sized complete pattern can be realized by means of splicing several small-sized photomasks (1) and performing photolithography, thereby facilitating processing and realization, and reducing the production and application costs. Further disclosed is a multi-optical-head parallel fast photolithography method.
An unidirectional nanopore dehydration-based functional polymer membrane or hydrogel membrane, preparation method thereof and device thereof. Adding an aqueous polymer solution or a polymer mixture solution into a mold through a sampling hole on the top of a container with a nanoporous filter film as the bottom, after closing said sampling hole, the water molecules in the solution are dehydrated in one direction downward through the nanopores of the filter film, and obtain said polymer membrane or hydrogel membrane on the upper surface of the nanoporous filter film; it can also undergo in situ polymerization with pyrrole in an aqueous solution to obtain a conductive PM or PHM modified by polypyrrole. The invention adopts a UND-based mold, and green processing obtains a novel polymer material with an ordered molecular arrangement, which has the characteristics of flexibility, transparency, and robust mechanical properties. The polymeric material has broad applications.
The present invention provides a polysubstituted selenium-containing cyclopent(hex)ene skeleton derivative and a synthesis method thereof. The polysubstituted selenium-containing cyclopent(hex)ene skeleton derivative is prepared by a one-pot method using an arylacetylene compound and an unsaturated selenide reagent as reaction materials, in the presence of a free radical initiator. The synthesis method of the present invention is simple and efficient, requires no metal catalyst, has mild reaction conditions, and has good functional group tolerance and broad substrate scope. Moreover, cyclopent(hex)ene compounds with different substituents are widely present in active drug molecules, and selenium-containing compounds also have good biological activity against tumors, oxidation, inflammation, bacteria, viruses and others. Therefore, a complex selenide-containing cyclopent(hex)ene skeleton derivative is obtained starting from a simple substrate by the synthesis method of the present invention by constructing a C—Se bond through a simple, efficient and sustainable strategy. The present invention has broad application prospects.
The invention provides a method and a system for generating a robust higher-order Poincaré sphere polarization state. The method includes: loading vortex phases into fully coherent vector beams for modulating them into left- and right-handed circularly polarized modes in a Poincaré sphere; synthesizing the left-handed and right-handed circularly polarized modes into a vector polarized light beam on the Poincaré sphere, and generating a polarization matrix of the Poincaré sphere; reducing the degree of spatial coherence of the polarized light, performing shaping to obtain a random electromagnetic beam, and simultaneously extracting polarization information in the polarization matrix and transferring the polarization information into a spatial correlation tensor of the random electromagnetic beam; and transmitting the random electromagnetic beam to a far field where the polarization information is transferred from the spatial correlation tensor into a polarization matrix of the random electromagnetic beam, to obtain a robust higher-order Poincaré sphere polarization state.
G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
94.
DRUG-CO-LOADED MICELLE, SYNERGISTIC DRUG SYSTEM THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF
h1h1 immune response, and administration can be performed via the intravenous system, thus reducing the potential immunogenicity and systemic toxicity of CpG.
A61K 31/7068 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Provided in the present invention is an embedded object recognition system based on image recognition, which system is applied to an embedded terminal. The system comprises: an image collection module, which is used for driving a camera to collect an image of a training object, performing feature extraction, and sending obtained image data to a PC-side model training module; the PC-side model training module, which is connected to the image collection module, performs model training on the image data, which is obtained by the image collection module, and generates a model parameter component that can be run in an embedded terminal; and a terminal inference module, which deploys the model parameter component into a terminal program of the embedded terminal, performs recompilation, burning and updating, and then performs target object recognition by using the model parameter component and according to an image of a target object that is collected by the image collection module. The present invention has a clear principle, is simple and easy to use, and can recognize a simple object; and the accuracy rate of recognizing the simple object by means of the system is about 98%.
The present invention discloses a fashion personality prediction and clothing recommendation method based on social networks, comprising: collecting language feature data of users in social networks; obtaining all proportional preferences of users' fashion personality types based on a fashion personality test scale; establishing a relationship model between language features and fashion personality types using machine learning algorithms; extracting clothing features, selecting clothing samples, quantifying style of clothing samples, and matching design style of clothing samples; obtaining user's preference values for clothing sample styles; constructing a clothing design model by combining relationship between fashion personality types and clothing style preference values, and correspondence between clothing styles and design elements with user's language feature and fashion personality type relationship model. More comprehensive and efficient exploration of consumers' personalized aesthetic preferences is enabled with significant improvements in model accuracy. Fashion personality is also defined, which helps clothing companies develop precise marketing strategies.
G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
97.
INVERTER PREDICTION CONTROL METHOD BASED ON OPTIMAL SWITCHING SEQUENCE MODEL
Provided in the present invention are an inverter prediction control method based on an optimal switching sequence model, the inverter being a T-type single-phase three-level inverter. The voltage state prediction control method comprises the following steps: 1) creating an output voltage model, the output voltage model comprising a plurality of small voltage vectors; 2) building an OSS-MPC prediction model, and, at a K moment, predicting an output current at the K+1 moment according to the MPC prediction model; 3) building a switching sequence set, each built switching sequence comprising two redundant small voltage vectors which have opposite effects on a direct-current capacitor voltage; 4) by adjusting the operating time of the redundant small voltage vectors, achieving dynamic adjustment of a direct-current voltage-dividing capacitor voltage; 5) dividing the switching sequence set by means of a reference current to obtain a candidate switching sequence, and finding the optimal switching sequence among the candidates; and 6) according to the optimal switching sequence, controlling a switch sequence generator to output a prediction control signal for controlling an inverter.
H02M 7/5387 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only, e.g. single switched pulse inverters in a bridge configuration
H02M 1/088 - Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters for the simultaneous control of series or parallel connected semiconductor devices
H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
98.
Fiwi network load balancing method and system based on edge computing
The present invention provides a FiWi network load balancing method and system based on edge computing. The method includes the following steps: establishing a path protection (PP) scheme; establishing a server protection (SP) scheme; and establishing a load balancing protection (LBP) scheme: when protection is provided for a user service, separately calculating and comparing network resource utilizations when the PP scheme and the SP scheme are performed for the service, and selecting a scheme with the lower network resource utilization to provide a service to the user service. The present invention can effectively restore a MEC service and reduce both a maximum MEC server load and consumption of protection bandwidth resources in a network, thereby implementing a balance between a resource load of a server and a traffic load of an optical fiber link.
The invention provides a multi-period upgrade scheduling method, including: setting a quantity of periods for optical fiber upgrade, and determining a maximum optical fiber length of upgrade in each period; randomly generating an upgrade scheduling sequence, and calculating a total upgrade gain of the sequence; randomly generating a new upgrade scheduling sequence, and calculating a total upgrade gain of the current sequence; calculating a difference obtained by subtracting a gain of the previous sequence from a gain of the current sequence, if the difference is greater than or equal to 0, replacing the previous upgrade scheduling sequence with the current upgrade scheduling sequence, and if the difference is less than 0, accepting the current upgrade scheduling sequence according to a probability value formula; and performing multiple iterations, and if a new upgrade scheduling sequence has not been updated when a set quantity of iterations is reached, terminating iteration.
A Salvia plebia and Scutellariae radix compound acne cream, a preparation method therefor and an application thereof. Stearic acid, vaseline, lanolin, glycerol monostearate and cetyl alcohol are heated and mixed to obtain an oil phase; glycerol and triethanolamine are fusion-mixed to obtain a water phase; and the water phase, the oil phase, a Scutellariae radix extract and a Salvia plebia extract are mixed, water is added to specified volume and the mixture is mixed uniformly to obtain the Salvia plebia and Scutellariae radix compound acne cream. The problems of large toxic and side effects, long treatment period and drug resistance of pathogenic bacteria of existing acne-treating drugs are solved. The Chinese medicine-based cream is prepared from a novel external preparation cream, has strong skin adhesion and good biocompatibility, and can effectively facilitate drugs to penetrate stratum corneum, reach an action site and exert a curative effect. The drug bioavailability is enhanced, the drug dosage is reduced, the curative effect is guaranteed, irritation caused by excessive local drug concentration can be avoided, and the use is convenient and safe.
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