Abstract

The present invention relates to a method for preparing an anhydrosugar alcohol using hydrol (namely, a crystalline mother liquor remaining after obtaining crystalline glucose from a crude glucose liquor). More particularly, the present invention relates to a method for preparing an anhydrosugar alcohol in a method for performing a dehydration reaction on the hydrogenated sugar so as to convert the hydrogenated sugar to an anhydrosugar alcohol, wherein the method for preparing an anhydrosugar alcohol is configured to use, as at least a portion of the hydrogenated sugar, the product obtained from the hydrogenation of the hydrol which is a by-product or waste generated during the production of glucose, thus relatively lowering the cost for a material as compared with a case of using a high purity raw material (for example, high purity sorbitol), to thus improve economical advantages, and further reduce the amount of waste and cost for disposal of the waste during the production of glucose.

IPC Classes  ?

• C07C 29/132 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group
• C07C 31/18 - Polyhydroxylic acyclic alcohols
• C07C 29/34 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions without formation of hydroxy groups by condensation involving hydroxy groups or the mineral ester groups derived therefrom, e.g. Guerbet reaction

Abstract

The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol (in particular, isosorbide, isomannide, isoidide, and the like) having a purity of 98% or higher and containing less than 0.1% of sorbitol and a sorbitan isomer, which are impurities, in a high total distillation yield of 94% or higher (more preferably, 95% or higher) by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, and then distilling the converted liquid over two or more stages by sequentially using a combination of an external condenser type wiped film evaporator and an internal condenser type short path evaporator.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• C07D 307/20 - Oxygen atoms
• B01D 3/00 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping

Abstract

The present invention relates to psicose 3-epimerase of SEQ ID NO:1, a composition for producing psicose containing the epimerase, and the psicose production method using the epimerase.

IPC Classes  ?

• C12N 9/90 - Isomerases (5.)
• C12N 15/61 - Isomerases (5)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 19/00 - Preparation of compounds containing saccharide radicals

Abstract

The present invention relates to a technique for producing an anhydrosugar alcohol using a hydrogenated sugar as a raw material and, more specifically, to a low-cost, highly efficient technique for producing a high-purity anhydrosugar alcohol (in particular, isosorbide, isomannide, isoidide, and the like) having a purity of at least 99% by adding an acid to a hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol and then distilling the resulting converted liquid in a single distillation step which adopts column distillation following thin-film distillation.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• B01J 27/053 - Sulfates
• B01J 31/10 - Ion-exchange resins sulfonated

Abstract

The present invention relates to a method for producing an anhydrosugar alcohol and, more specifically, to a method for producing an anhydrosugar alcohol which, when the step of subjecting a hydrogenated sugar to a dehydration reaction in a reactor so as to convert same to an anhydrosugar alcohol is performed, allows the hydrogenated sugar to be continuously introduced into the reactor and the produced anhydrosugar alcohol to be continuously discharged out of the reactor while the dehydration reaction is carried out, also prevents a reaction mixture from circulating inside and outside the reactor while the dehydration reaction is carried out, and thereby can significantly improve production efficiency compared with a conventional process adopting a batch or semi-batch type dehydration reaction and thus can be appropriately applied particularly to a large-scale anhydrosugar alcohol production process.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• B01J 31/10 - Ion-exchange resins sulfonated

Abstract

The present invention relates to a method for preparing an anhydrosugar alcohol using hydrol (namely, a crystalline mother liquor remaining after obtaining crystalline glucose from a crude glucose liquor). More particularly, the present invention relates to a method for preparing an anhydrosugar alcohol in a method for performing a dehydration reaction on the hydrogenated sugar so as to convert the hydrogenated sugar to an anhydrosugar alcohol, wherein the method for preparing an anhydrosugar alcohol is configured to use, as at least a portion of the hydrogenated sugar, the product obtained from the hydrogenation of the hydrol which is a by-product or waste generated during the production of glucose, thus relatively lowering the cost for a material as compared with a case of using a high purity raw material (for example, high purity sorbitol), to thus improve economical advantages, and further reduce the amount of waste and cost for disposal of the waste during the production of glucose.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• B01J 23/755 - Nickel

Abstract

The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol (in particular, isosorbide, isomannide, isoidide, and the like) having a purity of 98% or higher and containing less than 0.1% of sorbitol and a sorbitan isomer, which are impurities, in a high total distillation yield of 94% or higher (more preferably, 95% or higher) by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, and then distilling the converted liquid over two or more stages by sequentially using a combination of an external condenser type wiped film evaporator and an internal condenser type short path evaporator.

IPC Classes  ?

• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 31/26 - Hexahydroxylic alcohols
• B01J 19/24 - Stationary reactors without moving elements inside

Abstract

The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, then distilling the converted liquid, and crystallizing the distilled liquid in a solvent, the technique removing a crystallization solvent from a crystallization mother liquor generated during a crystallization step and then introducing the resultant product together with the distilled liquid and the converted liquid into a distillation step, thereby being capable of improving the total distillation yield of the anhydrosugar alcohol, improving distillation efficiency by improving the mobility of a distillate, and further reducing the amount of generated waste and treatment costs and thus highly efficiently preparing the high-purity anhydrosugar alcohol at reduced costs.

IPC Classes  ?

• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 29/94 - Use of additives, e.g. for stabilisation
• C07C 31/26 - Hexahydroxylic alcohols
• B01J 19/24 - Stationary reactors without moving elements inside

Abstract

The present invention relates to a method for preparing anhydrous sugar alcohol, and more particularly, to a cheap and highly efficient method for preparing anhydrous sugar alcohol having a high final purity of at least 99%, and having good ion content, pH, conductivity, and color properties. According to the method, a hydrogenated sugar is dehydrated so as to be transformed into anhydrous sugar alcohol, and a series of processes including distillation, crystallization, decoloration, and ion exchange resin treatment are conducted.

IPC Classes  ?

• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 29/94 - Use of additives, e.g. for stabilisation
• C07C 31/26 - Hexahydroxylic alcohols
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides

Abstract

The D-psicose 3-epimerase according to the present invention has superior activity of epimerizing the third carbon position of fructose to produce psicose. The epimerase of the present invention has a wide range of pH which is industrially advantageous, and has stability at a high temperature, and therefore, may enable mass production of psicose with high economic advantages when applied to industrialization. The epimerase of the present invention can be used effectively not only in functional sugar industries but also as a health food material and as a material for medicine or cosmetics.

IPC Classes  ?

• C12P 19/02 - Monosaccharides
• C12N 9/90 - Isomerases (5.)

Abstract

The present invention relates to a method for preparing high purity anhydrosugar alcohols using hydrogenated sugar, and more specifically, to a method for preparing high purity anhydrosugar alcohols (particularly, isosorbide, isomannide, isoidide, and the like) with a purity of 97.5% or higher (more preferably, 98.5% or higher) and a pH of a distillate of 3.7 or higher (more preferably, 4.0 or higher) in a distillation yield of 87% or higher (more preferably, 90% or higher) by adding an acid to hexitol so as to convert the same into anhydrosugar alcohols, and single-stage distilling the converted product by using an internal condenser type thin film evaporator.

IPC Classes  ?

• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 31/26 - Hexahydroxylic alcohols
• C07H 1/00 - Processes for the preparation of sugar derivatives

Abstract

The present invention relates to a production method for an anhydro sugar alcohol having a markedly reduced ion content and improved colour characteristics, and, more specifically, relates to a method for producing an anhydrous sugar alcohol having a markedly reduced ion content, markedly lowered electrical conductivity and improved colour characteristics, which is obtained by subjecting hydrogenated sugar (sugar alcohol) to a dehydration reaction and thereby converting same to an anhydrous sugar alcohol and then subjecting distilled water, which has been isolated through a distillation step, to a decolourizing process using activated carbon, and subsequently bringing the resulting decolourized substance into contact with an ion exchange resin.

IPC Classes  ?

• C07C 29/08 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by addition of hydroxy groups to unsaturated carbon-to-carbon bonds, e.g. with the aid of H2O2 by hydration of carbon-to-carbon double bonds with formation of absorption products in mineral acids and their hydrolysis the acid being phosphoric acid
• C07C 31/26 - Hexahydroxylic alcohols
• C07H 1/00 - Processes for the preparation of sugar derivatives

Abstract

The present invention relates to a starch-based liquid composition for pretreating filler, filler pretreated with the composition for making paper, and paper comprising the filler. More specifically, the present invention relates to a liquid composition for pretreating filler that―when used in pretreating filler for making paper―can highly load the filler in the paper, and thus can achieve improvement in ash retention and strength of paper in a papermaking process, and can save raw materials such as pulp according to the increase of filler content; filler pretreated with the composition for making paper; and paper comprising the filler.

IPC Classes  ?

• D21H 17/29 - Starch cationic
• D21H 17/67 - Water-insoluble compounds, e.g. fillers or pigments
• D21H 17/28 - Starch

Abstract

Disclosed is a method for the preparation of an anhydrosugar alcohol using a starch-derived hexitol such as sorbitol or mannitol. Anhydrosugar alcohol is in the form of a diol having two hydroxyl groups in the molecule thereof and has a very high utility value as a physical property modifier which can be used primarily in plastics. Representative examples of anhydrosugar alcohols include isosorbide and isomannide. These anhydrosugar alcohols are capable of increasing a glass transition temperature of and improving strength of PET, polyesters, polycarbonates, etc., and are therefore highly valuable as biodegradable environmentally-friendly bioplastics.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• C07B 35/04 - Dehydrogenation
• C07B 63/00 - PurificationSeparation specially adapted for the purpose of recovering organic compoundsStabilisationUse of additives
• C08G 63/58 - Cyclic ethersCyclic carbonatesCyclic sulfites

Abstract

The present invention relates to a method for preparing hydroxyalkyl starch. The method for preparing hydroxyalkyl starch comprises the steps of hydrolyzing starch, reducing the hydrolyzed starch, and substituting the reduced starch with hydroxyalkyl group in a dry process.

IPC Classes  ?

• C08B 31/10 - Alkyl or cycloalkyl ethers
• C08B 30/12 - Degraded or non-chemically modified starchBleaching of starch

Abstract

A method for distilling anhydrosugar alcohol and a method for manufacturing anhydrosugar alcohol by using the same are provided. The distillation method comprises a step of adding saccharide to a mixture solution containing anhydrosugar alcohol and distilling the resulting mixture, and the manufacturing method comprises a step of dehydrating sugar alcohol to form anhydrosugar alcohol and a step of adding saccharide to a mixture solution containing the anhydrosugar alcohol and distilling the resulting mixture. The saccharide may comprise one or more selected from monosaccharide, disaccharide and sugar alcohol.

IPC Classes  ?

• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 29/94 - Use of additives, e.g. for stabilisation
• C07C 29/128 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by alcoholysis
• C07C 31/26 - Hexahydroxylic alcohols

Abstract

Provided is a method for preparing a taxane derivative, comprising: carrying out condensation of a phenylisoserine derivatives having a protective group introduced thereto or a mixture of isomers thereof, as a side chain, with a baccatin III derivative or 10-deacetyl-baccatin III derivative to obtain a mixture of isomers; separating the isomers via chromatography; and carrying out a selective reversion of the stereochemical structure of a separated isomer, which is suitable for producing a taxane derivative in a large scale with high yield.

IPC Classes  ?

• C07D 305/14 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Abstract

Provided is a process for purifying a vancomycin wet body, comprising: dissolving a wet body obtained from a microorganism-fermented solution containing vancomycin into a water soluble solvent to a concentration of about 1 to 40 g/L and carrying out reverse osmosis filtration; and carrying out lyophilization of the filtered vancomycin. The process for purifying a vancomycin wet body provides high-purity vancomycin, while avoiding degradation of stability during a drying step.

IPC Classes  ?

• C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
• C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
• A61P 31/04 - Antibacterial agents

Abstract

The present invention relates to an aldohexose epimerase, an enzymatic preparation method of aldohexose epimer using the same, and a screening method of aldohexose epimerase.

IPC Classes  ?

• C12N 9/90 - Isomerases (5.)

Abstract

The present invention relates to a powder composition of hygroscopic substances prepared by dissolving hygroscopic substances in starch and/or a starch grain solution, by adding an emulsifier and/or edible oil and fat to the solution, and by alpharizing and powderizing the mixture, and a manufacturing method thereof. The characteristics of the powder composition of hygroscopic substances are that the above starch and starch matrix grain substance is alpharized to improve digestion rate, and at the same time to solve deliquescent and hygroscopic problems of the above hygroscopic substances and to improve the manufacturing and distribution processes.

IPC Classes  ?

• A23L 1/0522 - Starch; Modified starch; Starch derivatives, e.g. esters, ethers

Abstract

This invention is directed to a method for the preparation of docetaxel having an amorphous, anhydrous crystalline, or hydrated crystalline structure. In accordance with the invention, highly pure amorphous, anhydrous crystalline, or hydrated crystalline docetaxel can be produced with a high yield by using a solvent precipitation method, colloid formation method, etc.

IPC Classes  ?

• C07D 305/14 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems