A medical device having at least one invasive portion is disclosed. The medical device has a housing at least partially surrounding a tight chamber. The tight chamber sustains a pressure difference between an interior lumen of the tight chamber and the surrounding environment. The housing also has at least one deformable component. The housing is configured such that a state of deformation of the deformable component provides for a measurable indication of the pressure difference between the interior lumen of the tight chamber and the surrounding environment.
G01M 3/26 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1495 - Calibrating or testing in vivo probes
A method of operating a medical monitoring system includes providing stored program instructions for a software application. The software application is configured to be stored in a non-transitory memory of a computing device. Upon execution by a processor of the computing device, the software application is configured to (i) obtain measurement data, (ii) store image data of a nonmedical image on the non-transitory memory, (iii) modify the image data based on the measurement data to generate modified image data, and (iv) render the modified image data as a modified image on a display screen of the computing device. Modifying the image data includes changing a feature of the nonmedical image to represent the measurement data.
H04M 1/72427 - User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality for supporting games or graphical animations
An insertion device for inserting at least an insertable part of a medical device into a body tissue of a subject is proposed, that includes: at least one housing with at least one holding structure adapted to releasably receive the medical device, at least one insertion tool configured for inserting at least the insertable part of the medical device, at least one wheel comprising a guiding structure configured for guiding an axial movement of the insertion tool and the holding structure between a distal position and a proximal position, and at least one torsional drive configured for rotating the wheel upon activation, wherein the guiding structure comprises a shape with an eccentricity relative to a center of the wheel and/or relative to a turning point of the wheel, wherein the eccentricity is unequal to zero, and wherein the shape is configured to slow a linear movement around a turning point of the insertion tool.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
4.
BODY MOUNT FOR MOUNTING AT LEAST ONE TRANSDERMAL MEDICAL DEVICE TO A BODY SURFACE OF A USER
A body mount for mounting at least one transdermal medical device to a body surface of a user is disclosed. The body mount includes: at least one base element having at least one mounting surface for attachment to the body surface of the user, at least one capillary for taking up blood from the body of the user when the base element is attached to the body surface of the user; and at least one bleeding detector configured for detecting blood in the capillary. Further disclosed are a medical device including the body mount, a medical kit including the medical device, a method of monitoring a transdermal medical device, and a method of determining at least one physiological parameter in a body tissue of a user and computer programs and computer-readable storage media for performing the methods.
Methods for predicting glucose values which involve determining a predicction time window using historical data indicative of glucose level influencing events of a person having diabetes and at least one predicted glucose level influencing event. Further disclosed are data processing systems for predicting glucose values, medical servers, user devices, and computer programs.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A medical device for detecting at least one analyte in a body fluid, a method for assembling the medical device and a method of using the medical device are disclosed. The medical device comprises:
an analyte sensor having an insertable portion;
an insertion cannula receiving the insertable portion of the analyte sensor;
an electronics unit connected with the analyte sensor; and
a housing comprising an electronics compartment receiving the electronics unit and-a sensor compartment receiving the analyte sensor,
the sensor compartment forming a sealed compartment receiving the insertable portion of the analyte sensor,
the sealed compartment comprising detachable upper and lower caps,
the lower cap configured for detachment before insertion,
the insertion cannula being attached to the upper cap, wherein detaching the upper cap after insertion removes the insertion cannula,
wherein the electronics compartment at least partially surrounds the sensor compartment.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A computer-implemented method and system for predicting and displaying glucose values, including receiving CGM data, determining, based on the data, a plurality of first predicted glucose values (33) for a first prediction time window (30), determining, based on the data, that a hypoglycemia event is predicted to occur during a second prediction time window (31) which has a contemporaneous beginning with the first prediction time window (30) but is shorter than the first window (30), and determining a plurality of second predicted glucose values (34) for the second prediction time window (31) and displaying the plurality of second predicted glucose values (34) for the second prediction time window (31) while not displaying predicted glucose values subsequent to the second prediction time window (31).
An insertion device for at least partially inserting a medical device into a body tissue of a subject is disclosed. The insertion system comprises: at least one medical device holding structure; an insertion component movable with the medical device holding structure from a distal position to a proximal position; at least one locking member having a predefined tensile strength Ftu, wherein the locking member is configured for holding the medical device holding structure and the insertion component in the distal position; and at least one pusher configured for applying an external force to overcome the predefined tensile strength of the locking member.
Embodiments are described herein for optimizing and personalizing therapeutic protocols to treat a medical condition. An event of a therapeutic protocol may be determined. One or more triggering events may be detected for generating a notification associated with the event of the therapeutic protocol. The one or more triggering events may be determined to exceed a notification threshold indicating a level of confidence that a user will receive a notification transmitted in response to the one or more triggering events. The notification may be provided to a user to assist in treatment of a medical condition, such as a diabetic condition, in response to the detected triggering event associated with the event of the therapeutic protocol.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
10.
INSERTION SYSTEM AND METHOD FOR INSERTING A MEDICAL DEVICE
Insertion tool for inserting at least a part of a medical device into a subject, insertion device comprising the insertion tool and an insertion mechanism, and method for manufacturing the insertion tool, wherein the insertion tool comprises a penetrating portion that comprises a composite material comprising at least one first material and at least one second material. Wherein the first material is an amorphous material or amorphous composite and the second material is a fibrillary material or fibrillary composite or a crystalline material or crystalline composite. A fluid absorption of the first material of the composite material is higher than a fluid absorption of the second material of the composite material, and the insertion device is adapted to soften when in contact with a body fluid at least due to the fluid absorption of the amorphous material or amorphous composite.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 17/00 - Surgical instruments, devices or methods
A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
A61L 31/14 - Materials characterised by their function or physical properties
A computer-implemented method of determining a numerical analyte result value corresponding to a concentration of an analyte in a sample of a bodily fluid of a subject applied to a reagent test region, that includes step (a) determining a numerical analyte result value based on an image of the reagent test region by using an algorithm which takes into account one or more parameters, each parameter being adapted to take more than one value, step (b) displaying the numerical analyte result value and/or a corresponding analyte value range and/or a corresponding message on a display device and step (c) automatically checking for available updated values for one or more of the parameters on a remote server before executing step (a), and, for each available updated value, updating the corresponding parameter value to be taken into account in step (a).
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
12.
BATTERY RELAXATION WITH NON-CONFORMING BLUETOOTH® COMMUNICATION BEHAVIOR
A computer implemented method for conserving power during BLUETOOTH® communication performed by a BLUETOOTH® enabled peripheral computing device, the method comprising advertising availability of the BLUETOOTH® enabled peripheral computing device for pairing, receiving a scan request from a BLUETOOTH® enabled central computing device. transmitting a scan response to the BLUETOOTH® enabled central computing device in response to the scan request, establishing a connection with the BLUETOOTH® enabled central computing device, monitoring a power consumption indicator of the peripheral computing device, introducing a delay period to a response period to a connection event received from the central computing device if the monitored power consumption indicator meets at least one predefined criteria, and wherein the delayed response period causes the response to occur after a predetermined peripheral latency period but prior to a supervision timeout.
G06F 1/3212 - Monitoring battery levels, e.g. power saving mode being initiated when battery voltage goes below a certain level
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
H04W 48/16 - DiscoveringProcessing access restriction or access information
A medical device for detecting an analyte in a body fluid has a base body for reversibly attaching the medical device to a patient's body and has an insertable analyte sensor with first and second electrodes. An electronics unit is connected to the sensor. The first and second electrodes each have a first free end and a second end, the second ends being electrically connected to respective electric conductors connecting the respective electrodes to the electronics unit. The first electrode extending from the second end and the second electrode extending from the second end are at least partially in electric contact with the body tissue of a patient during use of the medical device. The electrical resistance of the first electric conductor and the electrical resistance of the second electric conductor is higher than the electrical resistance of the first electrode and the electrical resistance of the second electrode.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
This disclosure relates to a method, a mobile device, and a computer program, for managing medical data such as, e.g., glucose concentrations, by an electronic disease management system. In the method a change of the local time between generation of a first set of medical data and a second set of medical data is detected.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
17.
METHOD AND SYSTEM FOR DETERMINING CONCENTRATION OF AN ANALYTE IN A SAMPLE OF A BODILY FLUID, AND METHOD AND SYSTEM FOR GENERATING A SOFTWARE-IMPLEMENTED MODULE
A method for generating a module configured to determine concentration of an analyte in a sample of a body fluid is disclosed. The method includes providing a first set of measurement data derived from images of one or more test strips indicating a color transformation in response to a body fluid containing an analyte. The images can be recorded by multiple devices with differing cameras, software and/or hardware device configurations for image recording and image data processing. A neural network model can be generated in a machine learning process applying an artificial neural network and a module configured to determine concentration of an analyte in a second sample of a body fluid can be generated. Further, the present disclosure includes a system for generating the module as well as a method and a system for determining concentration of an analyte in a sample of a bodily fluid.
An insertion device for inserting a medical device into a subject is disclosed. The insertion device has a chamber for receiving the medical device, an insertion tool for inserting an insertable portion of the medical device, an insertion mechanism, a retraction mechanism for retracting the insertion tool from the subject after insertion, a retaining mechanism for retaining the insertion tool in an end position after retraction, an inner housing having the retaining mechanism and the retracted insertion tool in the end position, an inserter housing having the insertion mechanism as well as a chamber for receiving the inner housing. The inserter housing is formed of recyclable or biodegradable or compostable material, the insertion device has an ejection mechanism to remove the inner housing from the chamber when the insertion tool is retrained within the inner housing by the retaining mechanism, and the ejection mechanism is activatable by the user.
This disclosure relates to a filling apparatus for filling a reusable reservoir of a medical dispensing device, the filling apparatus has a receiving portion for a reusable reservoir, a supply container for containing a liquid medication, a first connection port for fluidly connecting an inner volume of the reusable reservoir with the supply container, and a sterilization device that is configured for sterilizing the inner volume of the reusable reservoir. In order to provide an improved sterilization, the filling apparatus also includes a discharging device for discharging deposit from the inner volume of the reservoir. The sterilization device includes a radiation source for providing radiation for sterilizing the reusable reservoir. The reusable reservoir is housed in a radiation chamber.
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
20.
METHOD AND DEVICES FOR PERFORMING AN ANALYTICAL MEASUREMENT
A method, a mobile device and a kit for performing an analytical measurement are disclosed, wherein outliers are eliminated. In the inventive method, a mobile device having a camera and a test strip for performing a color-change detection reaction are provided. A sample is applied to a test field of the test strip and an image of at least part of the test strip is captured. A region of interest in the image is determined and associated with a first sub-set of pixels. A color distribution is evaluated and outliers are eliminated in the first sub-set of pixels. A sub-region of interest is determined within the region of interest and is associated with a second sub-set of pixels. Mean values of the color distributions of the first sub-set of pixels and the second sub-set of pixels are compared to thereby determine homogeneity information of the image.
G06T 7/90 - Determination of colour characteristics
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
Disclosed is a method of continuously in vivo detecting an analyte in a bodily fluid over time, an analyte sensor system for in vivo continuously detecting an analyte in a bodily fluid over a measurement time span, and a computer program and a computer-readable storage medium. The method uses an analyte sensor with a working electrode that performs an electrochemical detection reaction with the analyte, and a further electrode having a redox material composition with silver and silver chloride. The method includes the following steps: monitoring a standard sensor signal derived by using the analyte sensor in a standard operation mode, comparing the standard sensor signal with a threshold to thereby determine if a change of the analyte sensor from the standard operation mode into an economy operation mode is required.
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
22.
MEDICAL INFUSION DEVICE WITH A LEAKAGE DETERMINING MODULE
This disclosure relates to a medical infusion device having a reservoir for holding a liquid medicament, a cannula assembly, a fluid line, a drive mechanism, a dispensing member for dispensing medicament from reservoir through the fluid line and the cannula assembly, and a leakage determining module. For a more convenient determination of leakage of liquid medicament, the leakage determining module includes an electronic probe for receiving odor molecules and/or flavor molecules of the liquid medicament and the leakage determining module has evaluation electronics to determine presence of odor and/or flavor of the liquid medicament based on readings of the electronic probe.
This disclosure teaches a computer-implemented method for providing a personalized healthcare parameter to a patient and a healthcare management system supporting a more reliable and error-free determination of a personalized healthcare parameter for the patient, such as a diabetes patient. The method involves providing a healthcare application and an interface application running in a data processing component having data processors.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
25.
AUTONOMOUS MANAGEMENT OF A DIABETIC CONDITION BASED ON MEALTIME AND ACTIVITY DETECTION
Management of a diabetic condition may be performed by detecting a mealtime and/or an increased level of activity associated with a user. The mealtime is detected based one or more mealtime indicators that may indicate a likelihood of an occurrence of a mealtime. Each mealtime indicator provides additional context around the likelihood of a mealtime. To assist in managing the diabetic condition, a user's elevated activity levels may be detected. The activity level of a user is detected based on one or more activity indicators. Each activity indicator provides additional context around the likelihood of an increased level of activity by the user. Management of the diabetic condition may be performed proximate a mealtime or a user exercising to increase the efficacy of management of the diabetic condition.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G06V 20/20 - ScenesScene-specific elements in augmented reality scenes
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H04W 4/029 - Location-based management or tracking services
26.
METHOD OF DETERMINING A FINAL NUMERICAL ANALYTE RESULT VALUE CORRESPONDING TO A CONCENTRATION OF AN ANALYTE IN A BODILY FLUID USING A MOBILE DEVICE
A method of determining an analyte concentration in a body fluid using a mobile device with a camera is disclosed. A corresponding computer program, a non-transitory computer-readable storage medium, a corresponding mobile device, and a corresponding kit are also disclosed. In step a of the method, a numerical analyte result value from an image of a color formation of a reagent test region is determined. In step b, the numerical analyte result value and/or a corresponding analyte value range and/or a corresponding message is displayed. In step c), after step a) and before step b), an upper bias is added to the numerical analyte result value if it exceeds an upper threshold value, or a lower bias is subtracted if it falls below a lower threshold value, or it is kept unchanged it neither threshold value is passed.
An analyte sensor for use in medical devices for measuring analyte data in an analyte carrying fluid, in particular for measuring glucose data, which includes: a first electrode being a working electrode, a second electrode, a substrate carrying the first electrode and the second electrode, at least one membrane which at least partially covers the first electrode, wherein the at least one membrane comprises a membrane material that is impermeable to the analyte carrying fluid and/or the analyte, wherein the at least one membrane comprises at least one opening, and wherein the at least one membrane is configured for controlling the flux of the analyte carrying fluid and/or the analyte to the first electrode via the at least one opening. Methods of operation, a continuous analyte monitoring system and a kit with such a sensor are also disclosed.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
28.
SYSTEM AND METHOD FOR ADAPTIVE GENERATION OF GRAPHICAL DATA OF PREDICTED DIAGNOSES
A method for generating a user interface of predicted disease progressions includes receiving medical data corresponding to patient visits to a healthcare provider, generating a diagnosis for the patient based on the medical data, and generating a predicted diagnosis for a future condition of the patient based upon the diagnosis, and a predictive model. The method further includes generating a timeline view of a diagnosis in the current patient visit and the predicted diagnosis. The graphical element of the diagnosis and the predicted diagnosis both include a graphical indicator of a diagnosis and at least one graphical sub-element of a physiological parameter relevant to the diagnosis. The method further includes generating a graphical connector between the graphical elements to indicate progression of time between a first time of the current patient visit and a second time.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G06F 3/04847 - Interaction techniques to control parameter settings, e.g. interaction with sliders or dials
G06T 11/20 - Drawing from basic elements, e.g. lines or circles
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
29.
SYSTEM AND METHOD FOR ADAPTIVE GENERATION OF GRAPHICAL DATA OF A TREATMENT HISTORY
A method for generating graphical data of a patient treatment history includes receiving medical data for the patient corresponding to patient visits to a healthcare provider and generating graphical data corresponding to a timeline view of the patient visits. The generated graphical data include first and second graphical elements corresponding to first and second diagnoses based on the medical data during a current patient visit and a prior patient visit. Each graphical element includes a graphical indicator of a diagnosis for a medical condition and at least one graphical sub-element, the at least one graphical sub-element being relevant to a physiological parameter selected from the medical data and related to the diagnosis. The method includes generating a first graphical connector between the second graphical element and the first graphical element, to indicate a progression of time between patient visits in the timeline view.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
An infusion delivery device has a reservoir for containing a liquid medicament, a dispensing member moveably arranged within the reservoir for dispensing liquid medicament out of the reservoir through an outlet of the reservoir, an actuation member for moving the dispensing member within the reservoir, and a controller for controlling the movement of the dispensing member within the reservoir by the actuation member. The controller determines an occlusion hindering the dispensing of liquid medicament out of the reservoir and provides a control signal to the actuation member upon determining the occlusion, to move the dispensing member in a reverse direction about a model-based displacement distance.
A method of evaluating the suitability of a mobile device for performing an analytical measurement based on a color formation reaction. The capability of the mobile device to have relevant settings of the mobile device controlled by software running on the mobile device is evaluated. The relevant settings pertain to image raw data processing steps to be carried out by the mobile device and may include a color space transformation and a tone mapping transformation. When the evaluation indicates that the mobile device is capable of having the relevant settings controlled by the software, control information indicating that the mobile device is suitable for performing the analytical measurement is provided. When the evaluation indicates that the mobile device is not capable of having the relevant settings controlled by the software, control information indicating that the mobile device is unsuitable for performing the analytical measurement is provided.
H04N 17/00 - Diagnosis, testing or measuring for television systems or their details
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1495 - Calibrating or testing in vivo probes
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
G06T 7/80 - Analysis of captured images to determine intrinsic or extrinsic camera parameters, i.e. camera calibration
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
H04N 23/62 - Control of parameters via user interfaces
32.
MEDICAL DEVICE ALERT, OPTIMIZATION, PERSONALIZATION, AND ESCALATION
An alert is used to inform a user that their blood glucose level has dropped below a threshold (e.g., the user is hypoglycemic) or has increased above a threshold (e.g., the user is hyperglycemic). There is a hierarchy of alerts from lowest priority to highest priority. The alert is communicated by a user device (e.g., a mobile device), which is, for example, a smartphone, smart watch, home automation device, or the like. The alert is modified in order to increase the likelihood that the user receives or acknowledges the alert within a minimal amount of time. An intensity level (e.g., a volume) of an alert is modified based on, for example, whether the user has acknowledged a previous alert. A modality or a sensory channel of an alert is changed if an initial alert does fails to elicit a response from the user.
G08B 3/10 - Audible signalling systemsAudible personal calling systems using electric transmissionAudible signalling systemsAudible personal calling systems using electromagnetic transmission
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1171 - Identification of persons based on the shapes or appearances of their bodies or parts thereof
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G06V 40/16 - Human faces, e.g. facial parts, sketches or expressions
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
H03G 3/32 - Automatic control in amplifiers having semiconductor devices the control being dependent upon ambient noise level or sound level
A method for storing measurement data detected by a sensor and indicative of an analyte in a body fluid sample using a system having a processor and a memory. First and second measurement data indicative of first and second measurement values measured by a sensor, respectively, are provided. A relative measurement value is determined by the processor and is indicative of a value difference between the first and second measurement values. The first measurement value is stored in a first storage area having a first storage size in the memory. The relative measurement value is stored in a second storage area having a second storage size in the memory that is smaller than the first storage size. An indicator is also stored in the memory and is assigned to the relative measurement storage data in the memory and is indicative of a characteristic of the relative measurement storage data.
A method of individualizing analyte value ranges used to categorize a concentration of an analyte in a sample of a bodily fluid of a subject applied to a reagent test region and determined using a mobile device having a processing device, as well as a corresponding computer program, a non-transitory computer-readable storage medium with corresponding instructions, a corresponding mobile device, and a corresponding kit. The method comprises the steps of determining a numerical analyte result value from an image of a color formation of the reagent test region, attributing the numerical analyte result value to a corresponding analyte value range, and adapting one or more range limit values based on a plurality of numerical analyte result values previously determined for different samples of the subject's bodily fluid taken at different points in time.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
An insertion system comprising at least one screw coupling configured for coupling at least one first element and at least one second element of the insertion system is disclosed. The screw coupling is configured such that the first element and the second element are assembled without rotational movement. The screw coupling comprises at least one radially flexible part configured for radial movement and/or deformation when assembling the first element and the second element, wherein the radially flexible part is a part of the first element or second element; and elastic means configured for applying a force in an axial direction to the screw coupling, wherein the elastic means is pre-loadable in the axial direction during assembly of the insertion system.
An insertion device has a guide sleeve at its proximal end that contacts the skin for an insertion process. A cap at the distal end of the device can be pressed to carry out the insertion process while moving in the direction of the proximal end. An inserter sleeve is at least partially within the guide sleeve and/or the cap and has a holder for the medical device, and the inserter sleeve is moveable with respect to the guide sleeve. A retractor is moveable along a movement path and retracts a portion provided with the medical device. An elastic element biases the retractor towards the distal end along the movement path. A retractor control controls the movement of the retractor by blocking or freeing the movement of the retractor along the movement path, and the retractor control is rotatable with respect to the retractor.
A method of determining a color expectation range for assessing the plausibility of an assumed reaction time value used in an analytical measurement based on a color formation reaction and a measurement method of performing an analytical measurement based on a color formation reaction by using a mobile device having a camera and a processor are disclosed. Further disclosed are a determination system for determining a color expectation range for assessing the plausibility of an assumed reaction time value used in an analytical measurement based on a color formation reaction, a mobile device having a camera and a processor, a kit for determining the concentration of at least one analyte in a sample of a body fluid having the mobile device as well as computer programs and computer-readable storage media having instructions which, when performed on the respective device, cause the device to perform the determination method and/or the measurement method.
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G06T 7/90 - Determination of colour characteristics
38.
METHODS AND DEVICES FOR DETERMINING THE CONCENTRATION OF AT LEAST ONE ANALYTE IN A BODILY FLUID
Methods and devices for determining the concentration of at least one analyte in a bodily fluid. Including a determination method of determining a color expectation range for assessing the plausibility of a color formation value obtained in an analytical measurement based on a color formation reaction and a measurement method of performing an analytical measurement based on a color formation reaction by using a mobile device having a camera and a processor. Further including a determination system for determining a color expectation range for assessing the plausibility of a color formation value obtained in an analytical measurement based on a color formation reaction. The determination system comprises a training set of optical test strips having a reagent test region. At least two of the training optical test strips are non-corrupted and at least two are corrupted.
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood sugars, e.g. galactose
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
Analyte sensor for use in medical devices for measuring analyte data such as glucose data, including: a power source providing electrical power to the analyte sensor, an enclosure of the analyte sensor, a sensor circuit powered by the power source and including two electrodes, wherein the electrodes each have a first portion that lies inside the enclosure and a second portion that lies outside of the enclosure. At least one protection unit is electrically coupled to the first portion of each of the two electrodes located inside the enclosure, wherein the at least one protection unit is configured to short-circuit the two electrodes in case a voltage signal from the sensor circuit applied to the electrodes exceeds a predetermined voltage threshold. A method for operating an analyte sensor is also disclosed.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
40.
DMS - INTERACTIVE PRODUCT IDENTIFICATION FOR A CALL CENTER
This disclosure lies in the field of a computer implemented method of routing a video call from a call center computer system comprising a controller, a transceiver, and a machine learning system, to a product service agent computer system assigned to a certain medical device product type and associated services. This disclosure involves using artificial intelligence in order to identify a medical device product based on recorded product image data. Further aspects of this disclosure provide a corresponding call center computer system for routing a video call initiated by a mobile device from the call center computer system to a medical device product service agent computer system as well as a computer-implemented method for generating a model of a medical device product type.
G08B 13/196 - Actuation by interference with heat, light, or radiation of shorter wavelengthActuation by intruding sources of heat, light, or radiation of shorter wavelength using passive radiation detection systems using image scanning and comparing systems using television cameras
H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
H04N 23/661 - Transmitting camera control signals through networks, e.g. control via the Internet
41.
BODY-WEARABLE MEDICAL DEVICE WITH A SEALING ELEMENT
A body-wearable medical device has first and second housing portions. The first housing portion has a female portion and the second housing portion has a male portion. The male portion is at least partially inserted into the female portion, thereby defining a circumferential clearance gap. A circumferential sealing element is arranged in the circumferential clearance gap between the female portion and the male portion. In order to provide a body-wearable medical device with improved sealing that is less prone to failure by stress and forces exerted on the body-wearable medical device, the female portion and the male portion are fixed to each other by a circumferential fixation glue arranged in the circumferential clearance gap between the female portion and the male portion next to the circumferential sealing element.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
A61B 50/00 - Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
42.
METHODS AND DEVICES FOR PERFORMING AN ANALYTICAL MEASUREMENT
A determination method of determining a dynamic coefficient of variation limit (CvTR, lim) for assessing validity of an optical test strip usable for an analytical measurement based on a color formation reaction is disclosed. Training sets of optical test strips and mobile devices are provided. A color reference card is also provided. Images are captured of reagent test regions of the optical test strip and of a color reference field(s) of the reference card. A training set of pairs of reagent test region coefficients of variation (CvTR) and corresponding minimum color reference field coefficients of variation (CvRF, min) are determined. A relation for determining the dynamic coefficient of variation limit (CvTR, lim) for the respective reagent test region is derived. The dynamic coefficient of variation limit (CvTR, lim) defines a maximum coefficient of variation (CvTR, max) for reagent test regions of non-corrupted optical test strips.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G06T 7/90 - Determination of colour characteristics
43.
BODY-WEARABLE MEDICAL DEVICE COMPRISING A SUPERABSORBENT SUBSTANCE
A body-wearable medical device has a medical device housing having a transcutaneous element configured for being at least partially inserted into a patient's body at an insertion site during use of the body-wearable medical device. A base is configured for reversibly attaching the body-wearable medical device during its use to a patient's skin. The base has a first side that faces the patient's body and that also has an adhesive for adhering the body-wearable medical device to a patient's skin. For reducing a likelihood of contamination by body fluid flowing out of the insertion lesion, the base on its first side also has a superabsorbent substance and at least one fluid channel. The fluid channel is configured to guide body fluid from the insertion site to the superabsorbent substance.
A61F 13/53 - Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the bodySupporting or fastening means thereforTampon applicators characterised by the absorbing medium
A61F 13/531 - Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the bodySupporting or fastening means thereforTampon applicators characterised by the absorbing medium having a homogeneous composition through the thickness of the pad
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
44.
ELECTRONIC CIRCUIT AND ANALYTE SENSOR SYSTEM AND METHOD OF OPERATING AN ANALYTE SENSOR AND SYSTEM
An electronic circuit configured to operate an analyte sensor, such as a glucose sensor, the circuit having at least a first and a second electrical connection configured to be connected to a first and a second electrode of the analyte sensor respectively. The electronic circuit has a voltage source and a common potential conductor section electrically provided on a potential of a pole of the voltage source, wherein, with the voltage source, an electric potential different from the potential of the common potential conductor section can be provided to the first electrical connection, and wherein the second electrical connection is connected to the common potential conductor section through one or more common potential connection paths wherein none of the common potential connection paths connects the second electrical connection to the common potential conductor section through fewer than three or more series-connected electronic components.
An inventive medical system has a housing with a first guiding surface. A preassembled module is received in the housing. The module includes electronics electrically connected to an analytical sensor, an insertion component configured for inserting the analytical sensor into body tissue of a user and a sterility cap at least partially surrounding the insertion component. The module has a second guiding surface. A protective cap is removably connected to the housing and covers the preassembled module. The protective cap is removable from the housing by pulling the protective cap from the housing. The first guiding surface guides the protective cap during the pulling of the protective cap from the housing and the second guiding surface guides the sterility cap during pulling the sterility cap from the insertion component. The length of the first guiding surface exceeds the length of the second guiding surface.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
46.
BODY WEARABLE ANALYTE SENSOR SYSTEM WITH INFRARED TEMPERATURE SENSOR DEVICE
An analyte sensor system has a transcutaneous analyte sensor. A housing is provided that has a lower side configured to be attached to the skin of a patient. An infrared (IR) temperature sensor detects the temperature (i) of the lower side of the housing or (ii) of the skin through a hole in the lower side of the housing. The IR temperature sensor faces and is spaced from the lower side of the housing or is spaced from the skin. An electronics unit has a processor that receives analyte sensor signals from the transcutaneous analyte sensor and temperature sensor signals from the IR temperature sensor device. The analyte sensor system may also include a contact temperature sensor in contact with a part of the housing carrying the IR temperature sensor or in contact with the circuit board.
Systems, devices and methods for assisting users in locating sources of carb-related food items. A hypoglycemic event is detected via a blood glucose monitoring device and a location of a user's mobile device is detected during the hypoglycemic event. In response to the location of the mobile device being at the user's home, carb-related food items in a refrigerator or carb-related food items purchased within a predefined period of time are displayed on the mobile device. In response to the location of the mobile device being outside of the user's home, locations of a predefined source of carbohydrates outside of the home are displayed on the mobile device.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
Medical devices and methods are disclosed for detecting an analyte in a body fluid. The medical device comprises an analyte sensor having an insertable portion adapted for insertion into body tissue of a user. An insertion cannula receives the analyte sensor therein. A housing forms a sealed sensor compartment receiving an insertable portion of the analyte sensor. The sealed sensor compartment comprises a detachable upper cap and a detachable lower cap. The detachable lower cap is configured for detachment before sensor insertion. The cannula is attached to the detachable upper cap, wherein the detachable upper cap is configured for detachment after insertion, thereby removing the insertion cannula. The analyte sensor is operably connected to an electronics unit comprising an interconnect device with at least one electronic component attached thereto
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B08B 5/00 - Cleaning by methods involving the use of air flow or gas flow
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
49.
ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR
The disclosure relates to an analyte sensor comprising a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which partially overlap with one another and have the same composition. The first and second silver layers intersect with one another to form a + or a T shape design. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
50.
DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME
Detection reagents, multi-analyte test elements, test systems, and multi-analyte measuring methods are provided. In particular, multi-analyte test elements have (1) a first working electrode and first counter electrode pair covered with a first analyte-specific reagent that includes an enzyme, a coenzyme and a first mediator and have (2) a second working electrode covered with a second analyte-specific reagent that includes an enzyme, a coenzyme and a second mediator, where the second mediator is different than the first mediator. The single counter electrode can be used as the counter electrode for both the first and second analyte measurements at their respective working electrodes. Moreover, the mediator concentrations, measurement ranges, and applied potential differences are not the same for each analyte-specific measurement.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A method for determining analyte concentration in a body fluid using a mobile device having a camera and a lidar sensor that have an overlapping field of view. In the method, an object is selected and the user is prompted to apply a body fluid sample to a reagent test region. The user is prompted to provide the object within the overlapping field of view of the camera and the lidar sensor. The processor of the mobile device generates a lidar measurement data set representing the object, which is compared to a pre-generated data set. When there is a degree of congruence from the comparison that is above a pre-determined minimum, the camera captures an image of the reagent test region having the body fluid sample applied thereto and concentration of analyte in the sample is determined. When the congruence is below a pre-determined minimum, image capturing is not allowed.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01S 17/88 - Lidar systems, specially adapted for specific applications
An analyte sensor (110) for determining at least one analyte and a method (140) for producing an analyte sensor (110) are disclosed. The analyte sensor (110) comprises:
a substrate (112);
a working electrode (118) and a conductive layer (124) located on different sites on the substrate (112);
a silver comprising layer (126) partially covering the conductive layer (124); and
a protective layer (128), which
comprises at least one electrically conductive material; and
covers the silver comprising layer (126) apart from at least one at least one hole that provides access for at least one body fluid comprising the at least one analyte to the silver comprising layer (126).
An analyte sensor (110) for determining at least one analyte and a method (140) for producing an analyte sensor (110) are disclosed. The analyte sensor (110) comprises:
a substrate (112);
a working electrode (118) and a conductive layer (124) located on different sites on the substrate (112);
a silver comprising layer (126) partially covering the conductive layer (124); and
a protective layer (128), which
comprises at least one electrically conductive material; and
covers the silver comprising layer (126) apart from at least one at least one hole that provides access for at least one body fluid comprising the at least one analyte to the silver comprising layer (126).
Although the analyte sensor (110) as disclosed herein has a reduced overall size, sufficient space is, nevertheless, provided for the silver comprising layer (126) coated by the protective layer (128) while, concurrently, further sufficient space remains which is neither coated by the silver comprising layer (126) nor by the protective layer (128).
An analyte sensor (110) for determining at least one analyte and a method (140) for producing an analyte sensor (110) are disclosed. The analyte sensor (110) comprises:
a substrate (112);
a working electrode (118) and a conductive layer (124) located on different sites on the substrate (112);
a silver comprising layer (126) partially covering the conductive layer (124); and
a protective layer (128), which
comprises at least one electrically conductive material; and
covers the silver comprising layer (126) apart from at least one at least one hole that provides access for at least one body fluid comprising the at least one analyte to the silver comprising layer (126).
Although the analyte sensor (110) as disclosed herein has a reduced overall size, sufficient space is, nevertheless, provided for the silver comprising layer (126) coated by the protective layer (128) while, concurrently, further sufficient space remains which is neither coated by the silver comprising layer (126) nor by the protective layer (128).
(FIG. 1)
Systems and methods for measuring an analyte include devices configured to perform an analyte testing operation. The devices include a wearable electronic device and a remote device operatively connected to each other and each having a processor, the processors cooperating with each other in the execution of program instructions to measure an analyte. The wearable electronic device includes a camera configured to generate a video stream, which is analyzed to identify missing test components, to identify the application of a body fluid on a test strip where the sample undergoes changes in one or more optical properties, the image of which is analyzed to determine a level of the analyte. The wearable electronic device further includes a head-up display (HUD) for providing output messages to the user relating to the performance and status of the analyte testing operation.
G06V 20/40 - ScenesScene-specific elements in video content
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
The present invention relates to an analyte sensor comprising a substrate, a first conductive material, a second conductive material, a first layer and a second layer, wherein the first and the second layer, independently of one another have a varying thickness along the length of the substrate and/or are located on the substrate as at least two fields separate from one another. The present invention furthermore relates to a method for manufacturing the analyte sensor and an analyte sensor system comprising the analyte sensor.
Systems and methods for measuring an analyte include devices configured to perform an analyte testing operation. The devices include a wearable electronic device and a remote device operatively connected to each other and each having a processor, the processors cooperating with each other in the execution of program instructions configured to direct the devices in the performance of the analyte testing operation. The wearable electronic device includes a camera configured to generate a video stream and one or more images relating to a user removing a test strip from a vial, producing a bodily fluid sample, and applying the sample to a deposit site of the test strip where the sample undergoes changes in one or more optical properties, the image of which is analyzed to determine a level of the analyte. The wearable electronic device further includes a head-up display (HUD) for providing output messages to the user relating to the performance and status of the analyte testing operation.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 90/92 - Identification means for patients or instruments, e.g. tags coded with colour
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
58.
METHOD AND SYSTEM FOR IMPROVED OPTICAL ANALYTE MEASUREMENTS
A method for measuring an analyte includes identifying a test strip in a video stream generated by a camera based on at least one registration mark associated with the test strip depicted in the video stream, identifying application of a fluid dose to a deposit site formed on the test strip based on the video stream, activating a timer in response to the identification of the application of the fluid dose, generating at least one optical measurement of a reagent located at a measurement site on the test strip, and generating a measurement of an analyte in the fluid dose based on the at least one optical measurement of the reagent only in response to the at least one optical measurement being generated after a predetermined minimum time period has elapsed and prior to a predetermined maximum time period elapsing subsequent to the activating of the timer.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G06V 20/40 - ScenesScene-specific elements in video content
G06V 40/20 - Movements or behaviour, e.g. gesture recognition
The present invention relates to a manual insertion aid for inserting a cannula unit into a cannula holder. The manual insertion aid comprises a handle and two jaws projecting from the handle and forming a receiving opening that is configured for engaging with a cannula unit. In order to provide a simple and lightweight insertion aid, the minimum clearance between the two jaws is greater than or equal to 1.5 mm and smaller than or equal to 7 mm, and wherein the maximum projecting length of each of the two jaws from the handle is greater than or equal to 4 mm and smaller than or equal to 18 mm.
This disclosure relates to a system, a sensor and a method for measuring an analyte concentration using an electrochemical analyte sensor having first and second electrodes. The first electrode reacts with the analyte for generating an electrical signal. The inventive method includes applying a modulated voltage signal between the first electrode and the second electrode, determining a current signal in response to the applied modulated voltage signal, determining an electric potential working point of the analyte sensor based on the determined current signal, operating the analyte sensor at the determined electric potential working point, and measuring the analyte concentration based on the electrical signal generated by the first electrode.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase involving dehydrogenase
61.
METHODS AND DEVICES FOR CONTROLLING AUTO WHITE BALANCE SETTINGS OF A MOBILE DEVICE FOR A COLOR BASED MEASUREMENT USING A COLOR REFERENCE CARD
A method of controlling auto white balance settings of a mobile device with a camera and preset auto white balance modes for performing a color based measurement comprising the steps of capturing an image of at least part of one or more gray fields of a color reference card, determining, for a region of interest within the image, a number of gray fields for which the color information for a first color and a second color shows overexposure as a first overexposure-number and a second overexposure-number, respectively, the first color relating to a smaller wavelength than the second color, and re-capturing the image with a warmer white balance mode if the first overexposure number is greater than the second overexposure number or re-capturing the image with a cooler white balance mode if the first overexposure number is smaller than the second overexposure number.
G01J 3/52 - Measurement of colourColour measuring devices, e.g. colorimeters using colour charts
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G06T 7/90 - Determination of colour characteristics
H04N 23/667 - Camera operation mode switching, e.g. between still and video, sport and normal or high and low resolution modes
H04N 23/88 - Camera processing pipelinesComponents thereof for processing colour signals for colour balance, e.g. white-balance circuits or colour temperature control
The application concerns a stickpack-type packaging comprising an elongate foil tube having two transverse sealing joints, such that a tightly closed fill space is provided in the foil tube for storing a product. It is proposed that a single disposable test strip is arranged in the fill space, wherein the test strip has a chemistry pad for detecting an analyte in a sample, and the chemistry pad is arranged at a distance at least from one of the transverse sealing joints.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
B65B 9/20 - Enclosing successive articles or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs the webs being formed into tubes in situ around the filling nozzles
B65B 61/00 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
B65B 61/02 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, or applying code or date marks on material prior to packaging
B65D 75/12 - Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks initially folded to form tubes with the ends of the tube closed by flattening and heat-sealing
B65D 75/44 - Individual packages cut from webs or tubes
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
The present invention relates to an analyte sensor comprising a substrate, at least one first electrode, at least one second electrode and at least one protective layer covering the at least one second electrode. The present invention further relates to a process for manufacturing the inventive analyte sensor as well as to an analyte sensor system comprising an analyte sensor according to the present invention and an electronics unit. The analyte sensor according to the present invention may mainly be used for conducting analyte measurements in a body fluid of a user.
A user device (e.g., a mobile device) may determine a first notification visibility level for the user health-related event based on a context. The user device may receive data associated with the user health-related event. The user device may determine an adherence level for the user health-related event based on the data associated with the user health-related event. The user device may determine a second notification visibility level for the user health-related event based on comparison of the adherence level to a plurality of predefined adherence thresholds. The user device may communicate, using the second notification visibility level, a notification associated with the user health-related event via the user device upon detection of a triggering event. The user device may group, based on the context, one or more user health-related events into a notification group.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
65.
ANALYTE MONITORING SYSTEM WITH A PART THAT IS ATTACHABLE TO THE BODY OF A PATIENT
A medical device having a body part that is attachable to a body of a patient is disclosed. The body part has a receiving opening through which a functional element can be reversibly introduced into the body of a patient by means of an inserting device, such as a needle. The body part has a seal that is adapted to seal at least a part of the receiving opening after removal of the inserting device.
A device and method are disclosed for supporting a patient with a disease, comprising a display facility, a user interface, a processor, and a user interface, and with an application module comprising program instructions, which are configured, on executing by the processor to bring about the following: providing medical protocols for diagnostic and/or therapeutic purposes, collecting time information concerning a future event which is a trigger for at least one medical protocol, selecting one of the medical protocols which indicates a group of cohesive protocol events which are spaced apart chronologically over a protocol period in accordance with a protocol regime, monitoring a chronological interval between a current date and the future even, and issuing a user start notice concerning the beginning of the medical protocol at a time which from a chronological point of view lies at least by the protocol period before the future event.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A device for transcutaneous insertion comprising a flexible insertion piece for transcutaneous insertion. The flexible insertion piece has a deformation sensor for detecting one or more deformation signals. Also disclosed is a transcutaneous insertion system having the device for transcutaneous insertion and a method of detecting deformation of at least a part of the insertion piece of a device for transcutaneous insertion.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
68.
Method and system for determining concentration of an analyte in a sample of a bodily fluid, and method and system for generating a software-implemented module
A method for generating a module configured to determine concentration of an analyte in a sample of a body fluid is disclosed. The method includes providing a first set of measurement data derived from images of one or more test strips indicating a color transformation in response to a body fluid containing an analyte. The images can be recorded by multiple devices with differing cameras, software and/or hardware device configurations for image recording and image data processing. A neural network model can be generated in a machine learning process applying an artificial neural network and a module configured to determine concentration of an analyte in a second sample of a body fluid can be generated. Further, the present disclosure includes a system for generating the module as well as a method and a system for determining concentration of an analyte in a sample of a bodily fluid.
The present invention relates to an analyte sensor comprising a substrate, at least one first electrode, at least one second electrode and at least one protective layer covering the at least one second electrode. The present invention further relates to a process for manufacturing the inventive analyte sensor as well as to an analyte sensor system comprising an analyte sensor according to the present invention and an electronics unit. The analyte sensor according to the present invention may mainly be used for conducting analyte measurements in a body fluid of a user.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
at least one electronics unit, wherein the analyte sensor is operably connected to the electronics unit, wherein the electronics unit comprises at least one interconnect device with at least one electronic component attached thereto, wherein the interconnect device fully or partially surrounds the housing.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B08B 5/00 - Cleaning by methods involving the use of air flow or gas flow
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
72.
ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR
The disclosure relates to an analyte sensor comprising a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which at least partially overlap with one another and have different compositions. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
73.
Electronic device with graphical user interface for continuous blood glucose values and associated data
A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
A method to determine a subject's blood glucose level non-invasively by analyzing an exhaled breath or another gaseous emanation from the subject. The method includes non-invasively detecting an amount of at least one volatile organic marker in the subject's exhaled breath or the subject's other gaseous emanation as marker data and determining the subject's blood glucose level based on the marker data. The amount of the volatile organic marker selected is negatively correlated to the blood glucose level.
An analyte sensor for determining at least one analyte and a method for producing an analyte sensor are disclosed. The analyte sensor has a substrate. A working electrode and a conductive layer are located on different sites on the substrate. A layer having silver and/or a silver compound partially covers the conductive layer. A protective layer covers (i) the layer having silver, and also covers (ii) a portion of the conductive layer. The disclosed analyte sensor significantly reduces noise during measurements. The method can be performed in an easier manner compared to producing prior art analyte sensors and allows considerably higher tolerances during production.
A medical system has a body-wearable medical device such as an insulin pump, a continuous glucose monitor, or a handheld diabetes management device. The system also includes a disposable container that has a reservoir for storing a foodstuff or a drug. The disposable container has an opening that provides access to the reservoir and a tamper evident closure that seals the opening. A fastener is provided to detachably fasten the disposable container to the body-wearable medical device. The fastener may be provided in the form of a mechanical, non-adhesive medical device fastener, e.g., a bracket that at least partially embraces the body-wearable medical device or the disposable container.
A method for determining the reliability of an analyte sensor is disclosed. The analyte sensor is an in vivo sensor. The method includes measuring at least one first temperature dependent signal, measuring at least one second temperature dependent signal which is different from the first temperature dependent signal and which is related to a current flow in the analyte sensor, and correlating the first temperature dependent signal and the second temperature dependent signal for determining the reliability of the analyte sensor.
A method of evaluating suitability of lighting conditions for detecting an analyte in a sample using a mobile device camera. A test strip is provided for detecting the analyte. A first image of the test strip is captured while an illumination source of the mobile device is turned off and a second image of the test strip is captured while the illumination source is turned on. A sample is applied to the test strip and the first and second images are compared to thereby determine the difference in lighting conditions between the first image and the second image. The comparison is used to derive information on suitability of the lighting conditions for analyte detection. The lighting conditions are indicated as suitable when a predetermined threshold amount of light intensity used for illumination of the test strip originates from the illumination source.
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
81.
METHOD AND MEANS FOR POSTPRANDIAL BLOOD GLUCOSE LEVEL PREDICTION
A method for predicting blood glucose levels, in particular, for postprandial blood glucose level prediction, the method being computer-implemented and comprising: receiving a first medical data set of a patient covering a time range, the first medical data set comprising glucose data and further other medical data of the patient, extracting a second medical data set from the first medical data set, wherein the second medical data set is a subset of the first medical data set and wherein the extracting comprises at least one of: identifying duplicates in the first medical data set and removing identified duplicates, identifying data values that lie above a predefined maximum threshold data value or identifying data values that lie below a predefined minimum threshold data value and removing data associated with the identified data values, identifying data values that differ from predetermined expected data values by more than a predetermined amount and removing data associated with the identified data values, identifying incomplete data for which data values are missing and removing identified incomplete data, identifying at least one predetermined time-dependent data pattern and removing data associated with the identified time-dependent data pattern, providing the extracted second medical data set as input to a blood glucose level prediction model, and predicting future blood glucose levels of the patient using the output of the blood glucose level prediction model based on the second medical data set.
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
82.
METHOD AND SYSTEM FOR AUTOMATED ACTIVITY RECOMMENDATION IN DIABETES TREATMENT PLANS
A method for generating activity recommendations in a diabetes treatment plan includes receiving physiological data, preferences, and suggested activities for a person with diabetes (PwD), generating physiological profiles for the PwD, providing the physiological profiles to a virtual physiological model, receiving projections from a virtual physiological model, generating weighted values based on the suggested activities and preference data, each weighted value corresponding to a likelihood of the PwD adhering to a suggested activity, ranking each activity based on the estimated change in the physiological characteristic of a projection associated with the activity relative to a baseline physiological projection and scaled by the weighted value corresponding to each activity, and generating an output including a predetermined number of suggested activities ordered based on the ranking of activities that provide a greatest change in the physiological characteristic given the likelihood of the PwD adhering to the suggested activities.
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A method is provided for monitoring medical information using a portable medical device and a mobile device, comprising: establishing a communication link between the mobile device and a download server; selecting, depending on the type of mobile device, a communication software package from a plurality of communication software packages accessible by the download server; downloading the selected communication software package to the mobile device over the link; installing the communication software package on the mobile device; wirelessly transferring medical data from the portable medical device to the mobile device using the installed communication software package; and uploading at least a portion of the medical data from the mobile device to a medical care server.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
84.
MEANS AND METHODS FOR IMPLANTING CELLS SECRETING A THERAPEUTIC COMPOUND
A device for implantation into a mammalian host has a dialysis tube with a lumen and a dialysis membrane enclosing the lumen. The dialysis tube has an outer diameter of 20 μm to 600 μm. The dialysis membrane has a molecular weight cutoff of from 25 kDa to 150 kDa and has a material composition of at least one of the following: polyethersulfone, polyarylethersulfone, polyethylene, polytetrafluoroethylene, polyvinylidene fluoride, and polypropylene. A therapeutic composition is disposed within the lumen and has cells that secrete a therapeutic compound. A matrix material embeds the cells. The matrix material is one or more of alginate, collagen, fibrin, extracellular matrix material, synthetic hydrogel, and acrylate. Also disclosed are a method of producing a device for implantation, a port system, and a cell secreting a therapeutic compound for use in treating disease by implantation of the cells in a device for implantation.
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
A61L 27/48 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
A method for screening a subject for the risk of chronic kidney disease (CKD) is provided. Marker data indicative for a plurality of marker parameters for a subject is received. The marker parameters indicate at least an age value, a time since diagnosis value indicative of a time since a diabetes diagnosis for the subject, a sample level of creatinine, an estimated glomerular filtration rate, a sample level of albumin, and a sample level of blood urea nitrogen. A risk factor is determined that indicates the risk of suffering CKD for the subject from the plurality of marker parameters.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
86.
Medical system and method of manufacturing thereof
An inventive medical system has a housing with a first guiding surface. A preassembled module is received in the housing. The module includes electronics electrically connected to an analytical sensor, an insertion component configured for inserting the analytical sensor into body tissue of a user and a sterility cap at least partially surrounding the insertion component. The module has a second guiding surface. A protective cap is removably connected to the housing and covers the preassembled module. The protective cap is removable from the housing by pulling the protective cap from the housing. The first guiding surface guides the protective cap during the pulling of the protective cap from the housing and the second guiding surface guides the sterility cap during pulling the sterility cap from the insertion component. The length of the first guiding surface exceeds the length of the second guiding surface.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
87.
Medical system and method of manufacturing thereof
An inventive medical system has a housing with a first guiding surface. A preassembled module is received in the housing. The module includes electronics electrically connected to an analytical sensor, an insertion component configured for inserting the analytical sensor into body tissue of a user and a sterility cap at least partially surrounding the insertion component. The module has a second guiding surface. A protective cap is removably connected to the housing and covers the preassembled module. The protective cap is removable from the housing by pulling the protective cap from the housing. The first guiding surface guides the protective cap during the pulling of the protective cap from the housing and the second guiding surface guides the sterility cap during pulling the sterility cap from the insertion component. The length of the first guiding surface exceeds the length of the second guiding surface.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
88.
METHOD FOR DETERMINING A MEMBRANE PROPERTY OF AN ANALYTE SENSOR
Method for determining at least one membrane property of an analyte sensor having at least two measurement electrodes. At least one of the measurement electrodes comprises at least one membrane element having at least one membrane property. The method includes:
a) generating at least one fast-transient voltage signal and applying the fast-transient voltage signal to the measurement electrodes at an application time t0;
b) measuring a first response signal U1 at a first time t1 and a second response signal U2 at a second time t2 with t0≠t1≠t2, wherein the application time t0 precedes the first time t1 and the second time t2;
c) determining a response signal U0 at the application time t0 by evaluating the first response signal U1 and the second response signal U2;
d) determining the at least one membrane property by evaluating the response signal U0 at the application time t0.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
89.
MEDICAL SOFTWARE FOR DISPLAYING AND ANALYZING BLOOD GLUCOSE DATA FOR USE IN A HETEROGENEOUS COMPUTING NETWORK IN MEDICAL PRACTICES
A method for updating medical practice software for a plurality of computing devices of a local network, comprising: determining, by a first computing device of the plurality of computing devices, what versions of the medical software are installed on the plurality of computing devices; receiving, at the first computing device, at least one software patch comprising at least one update for a version of the medical software installed on the plurality of computing devices; identifying, by the first computing device, which of the computing devices of the plurality of computing devices has installed thereon a version of the software that requires the software patch; transmitting, by the first computing device, a copy of the software patch to at least one of the computing devices that have been identified; and installing the software patch to update the medical practice software on the at least one computing device.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
at least one electronics unit, wherein the analyte sensor is operably connected to the electronics unit, wherein the electronics unit comprises at least one interconnect device with at least one electronic component attached thereto, wherein the interconnect device fully or partially surrounds the housing.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B08B 5/00 - Cleaning by methods involving the use of air flow or gas flow
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
The present invention relates to a method for the preparation of a working electrode, the method comprising application of a sensing material in several steps. Further, the present invention relates to an analyte sensor comprising the working electrode as well as to the use of the analyte sensor for detecting at least one analyte in a sample.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
at least one electronics unit, wherein the analyte sensor is operably connected to the electronics unit, wherein the electronics unit comprises at least one interconnect device with at least one electronic component attached thereto, wherein the interconnect device fully or partially surrounds the housing.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B08B 5/00 - Cleaning by methods involving the use of air flow or gas flow
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
at least one electronics unit, wherein the analyte sensor is operably connected to the electronics unit, wherein the electronics unit comprises at least one interconnect device with at least one electronic component attached thereto, wherein the interconnect device fully or partially surrounds the housing.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B08B 5/00 - Cleaning by methods involving the use of air flow or gas flow
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
97.
INSERTION SYSTEM AND METHOD FOR INSERTING A MEDICAL DEVICE
An insertion system comprises a medical device and an insertion device for inserting the medical device into a body tissue of a user, the insertion device comprising:
an insertion component-configured for inserting the medical device into the body tissue;
an insertion component retractor;
a cap;
a guide sleeve and an insertion sleeve guided therein;
a locking sleeve in the insertion sleeve; and
an elastic member positioned between the locking sleeve and the insertion component retractor;
wherein, for inserting the medical device, the cap, the insertion component retractor, the locking sleeve and the insertion sleeve are movable relative to the guide sleeve from a distal position to a proximal position, wherein the insertion device is separable from the medical device, wherein the insertion system is separation of the insertion device from the medical device releasing a movement of the locking sleeve from its proximal position to a further proximal position.
Medical device efficiency detection methods and systems including a photoplethysmography (PPG) sensor device, a processor, a memory, and machine readable instructions that may cause the system to receive a notification at the PPG device from the medical device upon delivery of the therapy treatment, use the PPG device to search for a signal response of the user based on the notification within a period of time to generate a response signal indicative of therapy treatment delivery, and transmit an alert when the response signal is not generated in the period of time indicative of a failure to detect sufficient therapy treatment delivery. The instructions may cause the system to transmit an alert when signal measurements from the PPG device of an infusion site are not within a sufficient signal range to indicate the infusion site is insufficient for delivery of the therapy treatment by the medical device.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
99.
ELECTROCHEMICAL SENSOR HAVING SYMMETRICALLY DISTRIBUTED ANALYTE SENSITIVE AREAS
The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
A61B 5/1477 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means non-invasive
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
An alert is used to inform a user that their blood glucose level has dropped below a threshold (e.g., the user is hypoglycemic) or has increased above a threshold (e.g., the user is hyperglycemic). There is a hierarchy of alerts from lowest priority to highest priority. The alert is communicated by a user device (e.g., a mobile device), which is, for example, a smartphone, smart watch, home automation device, or the like. The alert is modified in order to increase the likelihood that the user receives or acknowledges the alert within a minimal amount of time. An intensity level (e.g., a volume) of an alert is modified based on, for example, whether the user has acknowledged a previous alert. A modality or a sensory channel of an alert is changed if an initial alert does fails to elicit a response from the user.
G08B 3/10 - Audible signalling systemsAudible personal calling systems using electric transmissionAudible signalling systemsAudible personal calling systems using electromagnetic transmission
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
H03G 3/32 - Automatic control in amplifiers having semiconductor devices the control being dependent upon ambient noise level or sound level
patents
