A method for generating diabetes management parameter user interfaces includes providing stored program instructions of a first diabetes management application (DMA), the first DMA configured to be stored in a memory of an electronic device and, upon execution by a processor, the first DMA is configured to generate a first output display of a plurality of diabetes management parameters corresponding to a time series of analyte data, the plurality of diabetes management parameters depicting a trend of diabetes management parameter levels over time, generate a graphical indicator of a link to a second DMA stored in the memory, and activate the second DMA in response to an input selection of the link, wherein the second DMA is configured to be executed by the processor to generate a second output display of a current-time diabetes management parameter corresponding to the time series of the analyte data stored in the memory.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A medical device for detecting at least one physiological parameter of a user is proposed. The medical device (112) comprises: • at least one electronics unit (116); • at least one analytical sensor (136) for transdermal insertion into a body tissue of a user, the analytical sensor (136) having an insertable portion (138) configured for at least partially being inserted into the body tissue and at least one electrical connection portion (140) being electrically connected to the electronics unit (116); and • at least one housing (118) being made of at least one housing material (162), the housing (118) receiving the electronics unit (116). The analytical sensor (136), with at least the insertable portion (138), protrudes from at least one opening (152) in the housing (118). The medical device (112) further comprises at least one guiding element (156) at least partially made of at least one guiding material (170) softer than the housing material (162). The guiding element (156) at least partially surrounds the analytical sensor (136) at the opening (152). Further, a medical system (110) comprising the medical device (112) and a method of assembling a medical device (112) are proposed.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
3.
ELECTROCHEMICAL SENSING ELECTRODES AND BIOSENSORS AND PRODUCTION METHODS
Disclosed are methods for producing a sensing electrode in which an area of electrode material is applied to a substrate, a sensing chemistry material is applied to cover the electrode material, and a laser is used to form a laser cut the sensing chemistry material and the electrode material in a pattern to define at least a portion of the perimeter of the sensing electrode. The laser cut forms a gap physically and electrically separating the sensing chemistry material and the electrode material inside tire laser cut from the extraneous sensing chemistiy material and the electrode material outside the laser cut. The methods further provide for producing a plurality of sensing electrodes which are separated from a continuous substrate. Further disclosed are the sensing electrodes produced by such methods.
A medical device (146) for detecting an analyte in a body fluid is disclosed. The medical device (146) comprises: - an analyte sensor (110) having an insertable portion (115) adapted for at least partially being inserted into a body tissue of a user, wherein the analyte sensor (110) is configured for detecting the analyte in the body fluid, wherein the analyte sensor (110) comprises at least two conductor paths (136) configured for activating a sensor circuit, wherein the analyte sensor further comprises at least two electrodes (124) each comprising an electrode conductor path (125) configured for transmitting a sensor current for detecting the analyte; - an insertion component (147) comprising an insertion cannula (148), wherein the analyte sensor (110) is at least partially placed inside the insertion cannula (148); - an electronics unit comprising the sensor circuit; - a housing (154) having an electronics compartment (156) with the electronics unit at least partially received therein, wherein the housing (154) further comprises an open channel (170) which at least partially surrounds the analyte sensor (110) and the insertion component (147); and - a connector element (200), wherein the insertion component (147) is configured for being retracted from the open channel (170) thereby triggering an electrically contacting of the at least two conductor paths (136) of the analyte sensor (110) by the connector element (200) such that the sensor circuit is activated.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
5.
MEDICAL DEVICE HAVING AN INDICATOR FIELD SENSITIVE TO AN ENVIRONMENTAL PARAMETER
Medical device having an indicator field sensitive to an environmental parameter A medical device comprising a medical tool, an indicator area connected to the medical tool and a controller connected to the medical tool, wherein the indicator area comprises an indicator field which is a part sensitive to an environmental parameter, in particular humidity or humidity changes or temperature or temperature changes, that is configured to irreversibly change its appearance at a predetermined environmental parameter condition, in particular a predetermined humidity condition or predetermined humidity change condition or predetermined temperature condition or predetermined temperature change condition, wherein the medical device is configured such that at the time of use of the medical tool, the appearance of the indicator field is determined, and wherein the controller is configured to control the function of the medical tool based upon the determined appearance of the indicator field.
A sensor assembly comprising at least one analyte sensor (110) configured for transdermal detecting at least one analyte is proposed. The analyte sensor (110) comprises at least two electrodes (116, 118). The sensor assembly (124) comprises at least one electronics unit (126) connectable to the analyte sensor (110). The electronics unit (126) comprises at least one wake up unit (128) configured for determining conductivity of the analyte sensor (110) and for triggering a wake up of the sensor assembly (124) depending on the determined conductivity of the analyte sensor (110).
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A non-invasive analyte sensor (112) for on-skin wearing is described, comprising - at least one analyte-responsive layer (114) exhibiting at least one physical property depending on a quantity of the analyte, wherein the analyte-responsive layer (114) has a skin contacting surface (120) configured for directly or indirectly contacting the skin; and - at least one conversion layer (116).
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A method for determining a subject's analyte level is disclosed. The method comprises the steps of: • a) non-invasively detecting a first amount of at least one first volatile organic marker originating from a first source of the subject; • b) non-invasively detecting a second amount of at least the first volatile organic marker originating from a second source of the subject, wherein the second source is different from the first source; and • c) determining the subject's analyte level based on the first amount and on the second amount.
A non-invasive analyte sensor (112) is proposed, comprising at least two electrodes (114), each having a skin contacting surface (116). At least one of the electrodes (114) is a detection electrode (120). The detection electrode (120) comprises at least one analyte-responsive layer (124) and at least one conversion layer (126). At least one other of the electrodes (114) is configured as an auxiliary electrode (128) configured as either a counter, or a combined counter-reference electrode.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
10.
CALIBRATION METHOD AND ANALYTICAL METHOD OF DETECTING AN ANALYTE IN A BODILY FLUID
A calibration method is disclosed, for use in an analytical method of detecting at least one analyte in a sample of a bodily fluid by using a mobile device (110) having at least one camera (112) and at least one ambient light sensor (114), the calibration method comprising: a. providing a set of lighting conditions; and b. determining a calibration set, the calibration set comprising calibration functions (152) for each of the lighting conditions of the set of lighting conditions, each calibration function (152) providing a relationship between at least one item of optical information derived from at least one image captured with the camera (112) from at least one part of at least one test field (120) of an optical test element (118) under the respective lighting condition and a concentration of the analyte in a sample applied to the test field (120). Further disclosed is a computer-implemented analytical method and a mobile device (110), a computer program and a computer-readable storage medium for performing the analytical method.
G01N 21/84 - Systems specially adapted for particular applications
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
11.
IDENTIFICATION METHOD AND ANALYTICAL METHOD OF DETECTING AT LEAST ONE ANALYTE IN A SAMPLE OF A BODILY FLUID
A computer-implemented identification method of identifying a user and a computer-implemented analytical method are disclosed. The identification method is configured for an analytical method of detecting at least one analyte in a sample of a bodily fluid. The identification method comprises using a mobile device (110), specifically a mobile communication device, the mobile device (110) having at least one camera (112) and at least one RFID reader device (114). The identification method comprises: a. prompting the user to identify by bringing at least one RFID identifier (116) of the user into a communication range of the RFID reader device (114); b. reading out data from the RFID identifier (116) by using the RFID reader device (114); c. validating the data read out in step b., wherein the validating comprises checking if at least one valid item of identification information of the user was successfully transferred with the data from the RFID identifier (116) to the RFID reader device (114). Further disclosed is a computer program and a computer-readable storage medium for performing any one of the methods.
G16H 10/65 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records stored on portable record carriers, e.g. on smartcards, RFID tags or CD
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A method of titrating an antidiabetic for a patient is disclosed, along with a system for performing the method. The method includes providing a database having anonymized personal parameters for a plurality of previously managed subjects and generating cohorts from the plurality of previously managed subjects based on similarities in the anonymized personal parameters. The method further includes receiving patient specific personal parameters and identifying from the generated cohorts a patient similar cohort corresponding to the patient specific personal parameters. A titration output parameter to optimize may either be entered or computed. Based on the titration output parameter to optimize and the patient similar cohort, a customized titration protocol for the patient can then be derived.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A method of titrating an antidiabetic for a patient is disclosed, along with a system for performing the method. The method includes providing a database having anonymized personal parameters for a plurality of previously managed subjects and generating cohorts from the plurality of previously managed subjects based on similarities in the anonymized personal parameters. The method further includes receiving patient specific personal parameters and identifying from the generated cohorts a patient similar cohort corresponding to the patient specific personal parameters. A titration output parameter to optimize may either be entered or computed. Based on the titration output parameter to optimize and the patient similar cohort, a customized titration protocol for the patient can then be derived.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
14.
METHOD AND MOBILE DEVICE FOR DETECTING AN ANALYTE IN A SAMPLE OF A BODILY FLUID
A computer-implemented method of detecting at least one analyte in a sample of a bodily fluid by using a mobile device (136) having at least one camera (138), the method particu- larly comprising: c. weighting the potential item of intensity information on the optical detection feature of the optical detection reaction with at least one known item of position probability information on the optical detection reaction, wherein the known item of position probability information is a probability of a potential item of intensity information on the optical detection reaction to be a valid item of intensity information on the optical detection reaction depending on the associated item of position information on the optical detection, wherein the known item of position probability information on the optical detection reaction is determined by considering the associated item of position information on the optical detection reaction, wherein the at least one known item of position probability information considers at least one tolerance in a manu- facturing process of the optical test element (110) having an influence on the at least one predetermined position of the optical detection reaction on the test field (118); d. detecting the analyte by considering the weighted potential item of intensity infor- mation on the optical detection reaction for differentiating a valid item of intensity information on the optical detection reaction from an invalid item of intensity infor- mation.
A method for medication bolus calculation has been developed. The method includes receiving physiological measurements from an analyte sensor coupled to a user, receiving data corresponding to at least one meal event including a timestamp corresponding to when a meal was consumed, identifying a missed meal event time corresponding to a meal consumed by the user but not to the timestamp of any meal event, the recommended bolus being calculated based, at least in part, upon an length of time elapsed from the missed meal event time to a current time, and generating an output message indicating the recommended bolus of the medication.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
16.
MEDICAL SYSTEM AND A METHOD FOR MONITORING THE STORAGE CONDITIONS THEREOF
A medical system (110) and a method for monitoring the storage conditions of at least one medical system (110) are disclosed. The medical system (110) comprises: - at least one analyte sensor (112) for detecting at least one analyte in a bodily fluid, the analyte sensor (112) being configured for at least partial transcutaneous insertion into a body tissue (114) of a user (116); and - at least one disabling device (118) operably connected to the analyte sensor (112), the disabling device (118) comprising at least one monitoring element (120), the monitoring element (120) being configured for undergoing a change in at least one mechanical property when storage conditions of the analyte sensor (112) are outside a specification range, the mechanical property change being configured such that the transcutaneous insertion of the analyte sensor (112) into the body tissue (114) is irreversibly prevented.
A battery clip (110) for retaining at least one battery (162) to at least one battery contact pad (152) of a circuit carrier (150) is disclosed. The battery clip (110) comprises at least one housing (112). The housing (112) comprises at least one receptacle (114) for at least partially receiving the circuit carrier (150) and the battery (162). The receptacle (114) comprises at least one opening (116) through which the battery (162) and the circuit carrier (150) are at least partially insertable. The housing (112) comprises or is at least partially formed by at least one first contact spring element (166) and by at least one second contact spring element (118). The first contact spring element (166) and the second contact spring element (118) are configured for retaining the battery (162) to the battery contact pad (152) of the circuit carrier (150). The first contact spring element (166) is configured for contacting the battery (162) being arranged on a first side (168) of the circuit carrier (150) being inserted into the receptacle (114). The second contact spring element (118) is configured for contacting a second side (170) of the circuit carrier (150) being inserted into the receptacle (114), the second side (170) opposing the first side (168).
H01M 50/216 - Racks, modules or packs for multiple batteries or multiple cells characterised by their shape adapted for button or coin cells
H01M 50/244 - Secondary casingsRacksSuspension devicesCarrying devicesHolders characterised by their mounting method
H01M 50/247 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders specially adapted for portable devices, e.g. mobile phones, computers, hand tools or pacemakers
H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
A battery clip for retaining at least one battery to a circuit carrier is disclosed along with an assembly including a circuit carrier having a plurality of flexible tabs and a battery clip configured to be secured to the circuit carrier to securely retain a battery thereto for providing power to the circuit carrier. The battery clip includes a plurality of slots configured to mate with and receive the flexible tabs of the circuit carrier such that the battery clip and the circuit carrier are secured together such that a first terminal of a retained battery physically contacts and is in electrical communication with the circuit carrier's first pad, the battery clip further comprising one or more flexible conductive fingers configured to contact a second terminal of a retained battery to establish an electrical communication between the fingers and the second terminal, and wherein the battery clip comprises an electrically conductive material and establishes electrical communication between the fingers and the circuit carrier's second pad.
A medical device comprising a medical tool and an activation label connected to the medical tool, wherein the activation label comprises an activation code required for activating the medical device, the medical device comprising a controller connected to the medical tool, which is configured to receive an activation signal from a remote control device, and wherein the activation label comprises a temperature sensitive part that is configured to change its appearance at a predetermined temperature condition, in particular such that it masks at least part of the activation code if the predetermined temperature condition is reached.
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G09F 3/00 - Labels, tag tickets, or similar identification or indication meansSealsPostage or like stamps
20.
CUSTOMIZABLE CONTINUOUSLY UPDATED EVENT MONITORING FOR SCREENS ON COMPUTING DEVICE
A computing device may provide access to information related to the medical condition or health of the user in the form of an overlay notification when the computing device is displaying a graphical user interface. The overlay notification may be dynamically and/or continuously updated on the graphical user interface of the device in response to updated data. The overlay notification may be enabled/disabled in response to overlay notification triggering events/overlay notification removal events. When multiple types of information are to be displayed at a time, the computing device may group the information into a common overlay notification that may be updated dynamically and/or continuously in response to updated data. As the information that is provided in the overlay notification may be sensitive information, the information in the overlay notification may be prevented from being displayed until additional input is received from the user.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G06F 3/0481 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
21.
CUSTOMIZABLE CONTINUOUSLY UPDATED EVENT MONITORING FOR SCREENS ON COMPUTING DEVICE
A computing device may provide access to information related to the medical condition or health of the user in the form of an overlay notification when the computing device is displaying a graphical user interface. The overlay notification may be dynamically and/or continuously updated on the graphical user interface of the device in response to updated data. The overlay notification may be enabled/disabled in response to overlay notification triggering events/overlay notification removal events. When multiple types of information are to be displayed at a time, the computing device may group the information into a common overlay notification that may be updated dynamically and/or continuously in response to updated data. As the information that is provided in the overlay notification may be sensitive information, the information in the overlay notification may be prevented from being displayed until additional input is received from the user.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G06F 3/0481 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
22.
INSERTION TOOL FOR INSERTING AT LEAST ONE MEDICAL DEVICE INTO A BODY TISSUE
An insertion tool (114) for inserting at least one insertable part of a medical device into a body tissue of a subject is proposed. The insertion tool (114) comprises a shaft (116) configured for receiving the medical device. The shaft (116) comprises an insertable first end (118) and an adjustable second end (120).
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A medical device (112) having at least one invasive portion (124) is disclosed. The medical device (112) comprises at least one housing (114) at least partially surrounding at least one tight chamber (116). The tight chamber (116) is configured for sustaining a pressure difference between at least one interior lumen (118) of the tight chamber (116) and a surrounding environment (120). The housing (114) comprises at least one deformable component (122). The housing (114) is configured such that a state of deformation of the deformable component (122) provides for a measurable indication of the pressure difference between the interior lumen (118) of the tight chamber (116) and the surrounding environment (120).
A method of operating a medical monitoring system includes providing stored program instructions for a software application. The software application is configured to be stored in a non-transitory memory of a computing device. Upon execution by a processor of the computing device, the software application is configured to (i) obtain measurement data, (ii) store image data of a nonmedical image on the non-transitory memory, (iii) modify the image data based on the measurement data to generate modified image data, and (iv) render the modified image data as a modified image on a display screen of the computing device. Modifying the image data includes changing a feature of the nonmedical image to represent the measurement data.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
25.
SYSTEM AND METHOD FOR DISPLAYING AN IMAGE-BASED REPRESENTATION OF MEASUREMENT DATA
A method of operating a medical monitoring system includes providing stored program instructions for a software application. The software application is configured to be stored in a non-transitory memory of a computing device. Upon execution by a processor of the computing device, the software application is configured to (i) obtain measurement data, (ii) store image data of a nonmedical image on the non-transitory memory, (iii) modify the image data based on the measurement data to generate modified image data, and (iv) render the modified image data as a modified image on a display screen of the computing device. Modifying the image data includes changing a feature of the nonmedical image to represent the measurement data.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
An insertion device (112) for inserting at least an insertable part of a medical device (110) into a body tissue (114) of a subject is proposed, comprising: - at least one housing (116) with at least one holding structure (118) adapted to releasably receive the medical device (110), - at least one insertion tool (120) configured for inserting at least the insertable part of the medical device, - at least one wheel (132) comprising a guiding structure (134) configured for guiding an axial movement of the insertion tool (120) and the holding structure (118) between a distal position and a proximal position, and - at least one torsional drive (146) configured for rotating the wheel (132) upon activation, wherein the guiding structure (134) comprises a shape with an eccentricity relative to a center of the wheel (132) and/or relative to a turning point of the wheel (132), wherein the eccentricity is unequal to zero, and wherein the shape is configured to slow a linear movement around a turning point of the insertion tool (120).
A computer-implemented method and system for predicting and displaying glucose values, including receiving CGM data, determining, based on the data, a plurality of first predicted glucose values (33) for a first prediction time window (30), determining, based on the data, that a hypoglycemia event is predicted to occur during a second prediction time window (31) which has a contemporaneous beginning with the first prediction time window (30) but is shorter than the first window (30), and determining a plurality of second predicted glucose values (34) for the second prediction time window (31) and displaying the plurality of second predicted glucose values (34) for the second prediction time window (31 ) while not displaying predicted glucose values subsequent to the second prediction time window (31).
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
28.
BODY MOUNT FOR MOUNTING AT LEAST ONE TRANSDERMAL MEDICAL DEVICE TO A BODY SURFACE OF A USER
A body mount (126) for mounting at least one transdermal medical device (128) to a body surface (130) of a user (132) is disclosed. The body mount (126) comprises: - at least one base element (134) having at least one mounting surface (136) for attachment to the body surface (130) of the user (132), - at least one capillary (138) for taking up blood from the body of the user (132) when the base element (134) is attached to the body surface (130) of the user (132); - at least one bleeding detector (150) configured for detecting blood in the capillary (138). Further disclosed are a medical device (124) comprising the body mount (126), a medical kit (164) comprising the medical device (124), a method of monitoring a transdermal medical device (128), and a method of determining at least one physiological parameter in a body tissue of a user (132) and computer programs and computer-readable storage media for performing the methods.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/1459 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1495 - Calibrating or testing in vivo probes
The present disclosure refers to computer-implemented methods for predicting glucose values. Further, the present disclosure refers to a data processing system for predicting glucose values, a medical server, a user device, and a computer program.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
30.
METHODS AND DEVICES FOR PROVIDING BLACKLIST INFORMATION ON THE SUITABILITY OF A MOBILE DEVICE FOR PERFORMING ANALYTICAL MEASUREMENTS
A computer-implemented method of operating a cloud server (114) for providing blacklist information, the method comprising: i. providing a cloud-based blacklist database (124) on the cloud server (114), the blacklist database comprising blacklist information on a plurality of mobile devices (112), each mobile device (112) having at least one camera (116), the blacklist information comprising information on the suitability of at least one of the mobile devices (112)' hardware and the mobile devices (112)' software for performing at least one analytical measurement; ii. providing, upon request by a requesting mobile device (112) of the plurality of mobile devices (112), at least one item of blacklist information from the blacklist database to the requesting mobile device (112), the blacklist information comprising information on the suitability of at least one of the requesting mobile device's hardware and the requesting mobile device's software for performing the at least one analytical measurement; iii. receiving at least one item of individual check result information from a sending mobile device (112) of the plurality of mobile devices (112), the item of check result information comprising information on the suitability of at least one of the sending mobile device's hardware and the sending mobile device's software for performing the at least one analytical measurement; iv. evaluating the item of individual check result information for the necessity of updating the blacklist information on the blacklist database.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
31.
OPTIMIZATION AND PERSONALIZATION OF THERAPEUTIC PROTOCOLS
Embodiments are described herein for optimizing and personalizing therapeutic protocols to treat a medical condition. An event of a therapeutic protocol may be determined. One or more triggering events may be detected for generating a notification associated with the event of the therapeutic protocol. The one or more triggering events may be determined to exceed a notification threshold indicating a level of confidence that a user will receive a notification transmitted in response to the one or more triggering events. The notification may be provided to a user to assist in treatment of a medical condition, such as a diabetic condition, in response to the detected triggering event associated with the event of the therapeutic protocol.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
32.
OPTIMIZATION AND PERSONALIZATION OF THERAPEUTIC PROTOCOLS
Embodiments are described herein for optimizing and personalizing therapeutic protocols to treat a medical condition. An event of a therapeutic protocol may be determined. One or more triggering events may be detected for generating a notification associated with the event of the therapeutic protocol. The one or more triggering events may be determined to exceed a notification threshold indicating a level of confidence that a user will receive a notification transmitted in response to the one or more triggering events. The notification may be provided to a user to assist in treatment of a medical condition, such as a diabetic condition, in response to the detected triggering event associated with the event of the therapeutic protocol.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
33.
INSERTION SYSTEM AND METHOD FOR INSERTING A MEDICAL DEVICE THECHNICAL FIELD
Insertion tool for inserting at least a part of a medical device into a subject, insertion device comprising the insertion tool and an insertion mechanism, and method for manufac- turing the insertion tool, wherein the insertion tool comprises a penetrating portion that com- prises a composite material comprising at least one first material and at least one second material, wherein the first material is an amorphous material or amorphous composite, the second material is a fibrillary material or fibrillary composite or a crystalline material or crystalline composite, a fluid absorption of the first material of the composite material is higher than a fluid absorption of the second material of the composite material, and the insertion device is adapted to soften when in contact with a body fluid at least due to the fluid absorption of the amorphous material or amorphous composite.
A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
A61L 31/14 - Materials characterised by their function or physical properties
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 25/06 - Body-piercing guide needles or the like
A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
tutu), wherein the locking member (124) is configured for holding the medical device holding structure (120) and the insertion component (122) in the distal position; and - at least one pusher (126) configured for applying an external force to overcome the predefined tensile strength of the locking member (124).
An analytical system and an analytical method of determining at least one property of at least one sample of a bodily fluid are disclosed. The method comprises using at least one first mobile device (112) and at least one second mobile device (114), each of said mobile devices (112, 114) comprising at least one camera (116) and at least one processor (118). At least one first image is captured by the first mobile device (112) before applying the sample of the bodily fluid to a reagent test region (122). The first image is stored together with one time stamp and at least one first item of identity information in a database (128). The second mobile device (114) captures at least one second image and determines by using the stored information of the first mobile device (112) in the database (128) the at least one property of the sample.
A computer implemented method for conserving power during BLUETOOTH® communication performed by a BLUETOOTH® enabled peripheral computing device, the method comprising advertising availability of the BLUETOOTH® enabled peripheral computing device for pairing, receiving a scan request from a BLUETOOTH® enabled central computing device, transmitting a scan response to the BLUETOOTH® enabled central computing device in response to the scan request, establishing a connection with the BLUETOOTH® enabled central computing device, monitoring a power consumption indicator of the peripheral computing device, introducing a delay period to a response period to a connection event received from the central computing device if the monitored power consumption indicator meets at least one predefined criteria, and wherein the delayed response period causes the response to occur after a predetermined peripheral latency period but prior to a supervision timeout.
A computer implemented method for conserving power during BLUETOOTH® communication performed by a BLUETOOTH® enabled peripheral computing device, the method comprising advertising availability of the BLUETOOTH® enabled peripheral computing device for pairing, receiving a scan request from a BLUETOOTH® enabled central computing device, transmitting a scan response to the BLUETOOTH® enabled central computing device in response to the scan request, establishing a connection with tire BLUETOOTH® enabled central computing device, monitoring a power consumption indicator of the peripheral computing device, introducing a delay period to a response period to a connection event received from the central computing device if the monitored power consumption indicator meets at least one predefined criteria, and wherein the delayed response period causes the response to occur after a predetermined peripheral latency period but prior to a supervision timeout.
A computer-implemented method of determining a numerical analyte result value corresponding to a concentration of an analyte in a sample of a bodily fluid of a subject applied to a reagent test region, comprising step (a) determining a numerical analyte result value based on an image of the reagent test region by using an algorithm which takes into account one or more parameters, each parameter being adapted to take more than one value, step (b) displaying the numerical analyte result value and/or a corresponding analyte value range and/or a corresponding message on a display device and step (c) automatically checking for available updated values for one or more of the parameters on a remote server before executing step (a), and for each available updated value updating the corresponding parameter value to be taken into account in step (a).
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
39.
METHOD FOR ENHANCED DETERMINATION OF ANALYTE CONCENTRATION IN BODILY FLUID
The present invention relates to medical device for detecting at least one analyte in a body fluid, comprising a base body for attaching the medical device to a patient's body; an insertable analyte sensor comprising an insertable portion; and an electronics unit operably connected to the insertable analyte sensor, wherein the insertable analyte sensor comprises a first electrode and a second electrode, both, forming part of the insertable portion, wherein the first electrode extending from a second end towards its first free end and the second electrode extending from a second end towards its first free end are configured to be, during use of the medical device, at least partially in electric contact with the body tissue of a user. In order to mitigate a risk of an uncontrolled electric current flowing into a user's body, the electrical resistance of the first and second electric conductor is higher than the electrical resistance of the first electrode and second electrode.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
The present invention relates to a medical dispensing device comprising a first cylindrical reservoir, a second cylindrical reservoir, a first plunger movably arranged within the first cylindrical reservoir, a second plunger movably arranged within the second cylindrical reservoir, and a drive that is configured for moving the first plunger within the first cylindrical reservoir and that is further configured for moving the second plunger within the second cylindrical reservoir. For an improved dosing accuracy, the drive is configured to selectively move either the first plunger or the second plunger, and in that the drive is further configured to stop moving the first plunger within the first cylindrical reservoir when the first plunger reaches the ending point within the first cylindrical reservoir, and to start moving the second plunger within the second cylindrical reservoir.
The present invention relates to a medical infusion device system comprising a first dosing chamber for delivering at least a first minimum dosing amount of a liquid medicament, a second dosing chamber for delivering at least a second minimum dosing amount of the liquid medicament, a fluid line operatively coupled to the first dosing chamber and the second dosing chamber for conveying a total amount of liquid medicament for delivering by the first and second dosing chamber to an outlet of the fluid line, and a controller to control the total amount of liquid medicament. In order to provide relatively small and large dosing amounts both fast and accurate the second minimum dosing amount of the liquid medicament provided by the second dosing chamber larger than the first minimum dosing amount of the liquid medicament provided by the first dosing chamber.
An insertion device for inserting at least part of a medical device into a subject comprising a chamber for receiving the medical device, an insertion tool for inserting an insertable portion of the medical device, an insertion mechanism, a retraction mechanism for retracting the insertion tool from the subject after insertion, a retaining mechanism for retaining the insertion tool in an end position after retraction, an inner housing comprising the retaining mechanism and the retracted insertion tool in the end position, an inserter housing comprising the insertion mechanism as well as a chamber for receiving the inner housing, wherein the inserter housing is formed of recyclable or biodegradable or compostable material, the insertion device comprises an ejection mechanism to remove the inner housing from the chamber when the insertion tool is retrained within the inner housing by the retaining mechanism, and the ejection mechanism is activatable by the user.
The present invention relates to a filling apparatus for filling a reusable reservoir of a medical dispensing device, the filling apparatus comprises a receiving portion for a reusable reservoir, a supply container for containing a liquid medication, a first connection port for fluidly connecting an inner volume of the reusable reservoir with the supply container, and a sterilization device that is configured for sterilizing the inner volume of the reusable reservoir. In order to provide an improved sterilization, the filling apparatus further comprises a discharging device for discharging deposit from the inner volume of the inner volume, wherein the sterilization device comprises a radiation source for providing a radiation for sterilizing the reusable reservoir. The reusable reservoir is housed in a radiation chamber.
The present invention relates to a method (200) of continuously in vivo detecting at least one analyte in a bodily fluid over a time span, an analyte sensor system (100) for in vivo continuously detecting at least one analyte in a bodily fluid over a measurement time span, a computer program and a computer-readable storage medium. The method (200) makes use of at least one analyte sensor (102) comprising at least one working electrode (104), configured for performing at least one electrochemical detection reaction with the analyte, and at least one further electrode (106), the further electrode (106) comprising at least one redox material composition, the redox material composition comprising silver and silver chloride, the method (200) comprising the following steps: monitoring at least one standard sensor signal (132) derived by using the analyte sensor (102) in a standard operation mode, comparing the standard sensor signal (132) with at least one threshold, thereby determining if a change of an operation mode of the analyte sensor (102) from the standard operation mode into an economy operation mode is required.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1495 - Calibrating or testing in vivo probes
46.
MEDICAL INFUSION DEVICE COMPRISING A LEAKAGE DETERMINING MODULE
The present invention relates to a medical infusion device comprising a reservoir for holding a liquid medicament, a cannula assembly, a fluid line, a drive mechanism, a dispensing member for dispensing medicament from reservoir through the fluid line and the cannula assembly, and a leakage determining module. For a more convenient determination of leakage of liquid medicament, the leakage determining module comprises an electronic probe that is configured for receiving odor molecules and/or flavor molecules of the liquid medicament and in that the leakage determining module further comprises evaluation electronics that is configured to determine presence of odor and/or flavor of the liquid medicament based on readings of the at least one electronic probe.
The present disclosure refers to computer-implemented method and healthcare management system for providing a personalized healthcare parameter. The method is comprising the following: providing a healthcare application (20), and an interface application (25) running in a data processing component having a plurality of data processors; submitting, from the healthcare application (20) to the interface application (25), a service request indicative of a request for determining a first personalized healthcare parameter, the first personalized healthcare parameter being indicative of a first healthcare condition of the patient; in response to receiving the service request, generating a first input data request by the interface application (25); providing the first input data request to a first service application (26a) from a plurality of service applications, wherein each of the service applications (26) is configured to determine, for a patient, a respective personalized healthcare parameter in response to receiving respective personalized input data, and the first service application (26a) is configured to determine the first personalized healthcare parameter; receiving first input data information in the interface application (25), the first input data information being indicative of a data specification of first input data required by the first service application (26a) for determining the first personalized healthcare parameter; receiving the first input data information in the healthcare application (20); generating first personalized input data in the healthcare application (20), the first personalized input data being generated according to the first input data information; receiving the first personalized healthcare parameter in the healthcare application (20), wherein the first personalized healthcare parameter was determined in response to receiving the first personalized input data in the first service application (26a), such determining comprising processing the first personalized input data; and outputting the first personalized healthcare parameter to a receiving device (27; 28) connected to the data processing component (2).
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
Analyte sensor morphology The invention relates to an analyte sensor for use in medical devices for measuring analyte data in an analyte carrying fluid, in particular for measuring glucose data, comprising: a first electrode (101) being a working electrode, a second electrode, a substrate (100) carrying the first electrode and the second electrode, at least one membrane (104) which at least partially covers the first electrode (101), wherein the at least one membrane (101) comprises a membrane material that is impermeable to the analyte carrying fluid and/or the analyte, wherein the at least one membrane comprises at least one opening (107), and wherein the at least one membrane (104) is configured for controlling the flux of the analyte carrying fluid and/or the analyte to the first electrode (101) via the at least one opening (107).
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
49.
METHOD OF DETERMINING A FINAL NUMERICAL ANALYTE RESULT VALUE CORRESPONDING TO A CONCENTRATION OF AN ANALYTE IN A BODILY FLUID USING A MOBILE DEVICE
A method of determining an analyte concentration in a bodily fluid using a mobile device with a camera, as well as a corresponding computer program, a non-transitory computer- readable storage medium with corresponding instructions, a corresponding mobile device, and a corresponding kit. The method comprises step a: determining a numerical analyte result value from an image of a color formation of a reagent test region, step b: displaying the numerical analyte result value and/or a corresponding analyte value range and/or a corresponding message, wherein in a step c) after step a) and before step b) an upper bias is added to the numerical analyte result value if it exceeds an upper threshold value, or a lower bias is subtracted if it falls below a lower threshold value, or it is kept unchanged it neither threshold value is passed.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
50.
METHOD OF INDIVIDUALIZING ANALYTE VALUE RANGES USED TO CATEGORIZE A CONCENTRATION OF AN ANALYTE
A method of individualizing analyte value ranges used to categorize a concentration of an analyte in a sample of a bodily fluid of a subject applied to a reagent test region and determined using a mobile device having a processing device, as well as a corresponding computer program, a non-transitory computer-readable storage medium with corresponding instructions, a corresponding mobile device, and a corresponding kit. The method comprises the steps of determining a numerical analyte result value from an image of a color formation of the reagent test region, attributing the numerical analyte result value to a corresponding analyte value range, and adapting one or more range limit values based on a plurality of numerical analyte result values previously determined for different samples of the subject's bodily fluid taken at different points in time.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
An insertion system (114) comprising at least one screw coupling (118) configured for coupling at least one first element (110) and at least one second element (112) of the insertion system (114) is disclosed. The screw coupling (118) is configured such that the first element (110) and the second element (112) are assembled without rotational movement. The screw coupling (118) comprises - at least one radially flexible part (120) configured for radial movement and/or deformation when assembling the first element (110) and the second element (112), wherein the radially flexible part (120) is a part of the first element (110) or second element (112); - elastic means (122) configured for applying a force in an axial direction (124) to the screw coupling (118), wherein the elastic means (122) are preloadable in the axial direction (124) during assembly of the insertion system (114).
A method for generating graphical data of a patient treatment history includes receiving medical data for the patient corresponding to patient visits to a healthcare provider and generating graphical data corresponding to a timeline view of the patient visits. The generated graphical data include first and second graphical elements corresponding to first and second diagnoses based on the medical data during a current patient visit and a prior patient visit. Each graphical element includes a graphical indicator of a diagnosis for a medical condition and at least one graphical sub-element, the at least one graphical sub-element being relevant to a physiological parameter selected from the medical data and related to the diagnosis. The method includes generating a first graphical connector between the second graphical element and the first graphical element, to indicate a progression of time between patient visits in the timeline view.
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
53.
SYSTEM AND METHOD FOR ADAPTIVE GENERATION OF GRAPHICAL DATA OF PREDICTED DIAGNOSES
A method for generating a user interface of predicted disease progressions includes receiving medical data corresponding to patient visits to a healthcare provider, generating a diagnosis for the patient based on the medical data, and generating a predicted diagnosis for a future condition of the patient based upon the diagnosis, and a predictive model. The method further includes generating a timeline view of a diagnosis in the current patient visit and the predicted diagnosis. The graphical element of the diagnosis and the predicted diagnosis both include a graphical indicator of a diagnosis and at least one graphical sub-element of a physiological parameter relevant to the diagnosis. The method further includes generating a graphical connector between the graphical elements to indicate progression of time between a first time of the current patient visit and a second time.
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
54.
INSERTION DEVICE, INSERTION SYSTEM AND METHOD FOR INSERTING A MEDICAL DEVICE
Insertion device, Insertion system and method for inserting a medical device Insertion device for at least partially inserting a medical device such as an analyte sensor through the skin of a subject, the insertion device having a proximal end to be put in contact with the skin and a distal end opposite to the proximal end, the insertion device comprising: a guide sleeve being provided at the proximal end and to be placed in contact with the skin for an insertion process; a cap being provided at distal end, which can be pressed on to carry out at least part of the insertion process while moving in the direction of the proximal end; an inserter sleeve provided at least partially within the guide sleeve and/or the cap and being provided with a holder for the medical device and the inserter sleeve being moveable with respect to the guide sleeve; a retractor configured to retract a portion provided with the medical device, the retractor being moveable along a movement path; an elastic element such as a spring, which can bias the retractor towards the distal end along the movement path; a retractor control element which controls the movement of the retractor by blocking or freeing the movement of the retractor along the movement path and which is itself moveable such as rotatable with respect to the retractor. The invention further refers to an insertion system and an insertion method.
The present invention relates to an infusion delivery device comprising a reservoir that is configured for containing a liquid medicament, a dispensing member that is moveably arranged within the reservoir for dispensing liquid medicament out of the reservoir through an outlet of the reservoir, an actuation member that is configured for moving the dispensing member within the reservoir, and a controller that is configured for controlling the movement of the dispensing member within the reservoir by the actuation member, wherein the controller is further configured to determine an occlusion hindering the dispensing of liquid medicament out of the reservoir and that is configured to provide a control signal to the actuation member, upon determining an occlusion, to move the dispensing member in a reverse direction about a displacement distance. In order to prevent an overdosing or underdosing in case of an occlusion, the displacement distance is a model-based displacement distance.
The invention relates to an analyte sensor (100) for use in medical devices for measuring analyte data, in particular for measuring glucose data, comprising: a power source (102) for providing electrical power to the analyte sensor (100), an enclosure (101) of the analyte sensor, a sensor circuit (103) powered by said power source and comprising two electrodes (105, 106), wherein said electrodes (105, 106) each have a first portion (105a, 106a) that lies inside the enclosure (101) and a second portion (105b, 105b) that lies outside of the enclosure (101), at least one protection unit (107), wherein said protection unit (107) is electrically coupled to the first portion (105a, 106a) of each of the two electrodes (105, 106) that is located inside the enclosure (101), and wherein said at least one protection unit (107) is configured to short-circuit the two electrodes (105, 106) in case a voltage signal from the sensor circuit (103) applied to the electrodes (105, 106) exceeds a predetermined voltage threshold. The invention further relates to a method (300) for operating an analyte sensor.
The invention relates to a body-wearable medical device with a medical device housing comprising a transcutaneous element that is configured for being at least partially inserted into a patient's body at an insertion site during use of the body-wearable medical device, and a base portion that is configured for reversibly attaching the body-wearable medical device during its use to a patient's skin, wherein the base portion comprises a first side that during use of the body-wearable medical device faces the patient's body and that comprises an adhesive for adhering the body-wearable medical device to a patient's skin. For reducing a likelihood of a contamination by bodily fluid flowing out of the insertion lesion, the base portion on its first side further comprises a superabsorbent substance and at least one fluid channel, the at least one fluid channel being configured to guide bodily fluid from the insertion site to the superabsorbent substance.
The present invention relates to a body-wearable medical device comprising a first housing portion and a second housing portion, the first housing portion having a female portion and the second housing portion having a male portion, the male portion is at least partially inserted into the female portion thereby defining a circumferential clearance gap, wherein a circumferential sealing element is arranged in the circumferential clearance gap between the female portion and the male portion. In order to provide a body-wearable medical device comprising an improved sealing that is less prone to failure by stress and forces exerting on the body-wearable medical device, the female portion and the male portion are fixed to each other by a circumferential fixation glue that is arranged in the circumferential clearance gap between the female portion and the male portion next to the circumferential sealing element.
Methods and devices for determining the concentration of at least one analyte in a bodily fluid A determination method of determining a color expectation range (132) for assessing the plausibility of a color formation value obtained in an analytical measurement based on a color formation reaction and a measurement method of performing an analytical measurement based on a color formation reaction by using a mobile device (112) having a camera (114) and a processor (130) are disclosed. Further disclosed are a determination system (110) for determining a color expectation range (132) for assessing the plausibility of a color formation value obtained in an analytical measurement based on a color formation reaction. The determination system comprises a training set of optical test strips (116) having a reagent test region (120). At least two of the training optical test strips are non-corrupted (122) and at least two are corrupted (124).
A determination method of determining at least one color expectation range (128) for assessing the plausibility of an assumed reaction time value used in an analytical measurement based on a color formation reaction and a measurement method of performing an analytical measurement based on a color formation reaction by using a mobile device (112) having a camera (114) and a processor (126) are disclosed. Further disclosed are a determination system (110) for determining at least one color expectation range (128) for assessing the plausibility of an assumed reaction time value used in an analytical measurement based on a color formation reaction, a mobile device (112) having at least one camera (114) and at least one processor (130), a kit (134) for determining the concentration of at least one analyte in a sample of a bodily fluid (128) comprising said mobile device (112) as well as computer programs and computer-readable storage media comprising instructions which, when performed on the respective device cause the device to perform the determination method and/or the measurement method.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
61.
METHODS AND DEVICES FOR PERFORMING AN ANALYTICAL MEASUREMENT
vTR, limvTRvRF, minvTR, limvRF, minvTR, limvTR, maxvTR, max) for reagent test regions (114) of non-corrupted optical test strips (116). Further, a measurement method of performing an analytical measurement based on a color formation reaction by using a mobile device (122) having a camera (124) and a processor (138), a determination system (110), a mobile device (122), computer programs and computer-readable storage media are disclosed.
The invention refers to an electronic circuit configured to operate an analyte sensor, such as a glucose sensor, the circuit having at least a first and a second electrical connection configured to be connected to a first and a second electrode of the analyte sensor respectively, wherein the electronic circuit has a voltage source and a common potential conductor section electrically provided on a potential of a pole of the voltage source, wherein with the voltage source an electric potential different to the potential of the common potential conductor section can be provided to the first electrical connection; and wherein the second electrical connection is connected to the common potential conductor section through one or more common potential connection paths and wherein none of the common potential connection paths connects the second electrical connection to the common potential conductor section through fewer than three or more series-connected electronic components.
The present invention relates to a computer-implemented method, a mobile device, and a computer program, for managing medical data such as, e.g., a glucose concentrations, by an electronic disease management system comprising detecting a change of the local time between generation of a first set of medical data and a second set of medical data.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G01N 33/487 - Physical analysis of biological material of liquid biological material
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
64.
ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR
The disclosure relates to an analyte sensor comprising a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which partially overlap with one another and have the same composition. The first and second silver layers intersect with one another to form a + or a T shape design. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/30 - Electrodes, e.g. test electrodesHalf-cells
The present invention provides analyte sensor system which comprises a body wearable analyte sensor device, comprising a transcutaneous analyte sensor, a housing comprising a lower side which can be attached to the skin of a patient, a IR temperature sensor which is configured to detect the temperature of the lower side of the housing or to detect the temperature of the skin, and wherein the IR temperature sensor faces without contact the lower side of the housing, and a processor configured to receive signals from the analyte sensor and from the IR temperature sensor. In addition, a method of determing an analyte concentration using an analyte sensor system (1) of the invention is provided.
Systems and methods for measuring an analyte include devices configured to perform an analyte testing operation. The devices include a wearable electronic device and a remote device operatively connected to each other and each having a processor, the processors cooperating with each other in the execution of program instructions to measure an analyte. The wearable electronic device includes a camera configured to generate a video stream, which is analyzed to identify missing test components, to identify the application of a body fluid on a test strip where the sample undergoes changes in one or more optical properties, the image of which is analyzed to determine a level of the analyte. The wearable electronic device further includes a head-up display (HUD) for providing output messages to the user relating to the performance and status of the analyte testing operation.
A method for measuring an analyte includes identifying a test strip in a video stream generated by a camera based on at least one registration mark associated with the test strip depicted in the video stream, identifying application of a fluid dose to a deposit site formed on the test strip based on the video stream, activating a timer in response to the identification of the application of the fluid dose, generating at least one optical measurement of a reagent located at a measurement site on the test strip, and generating a measurement of an analyte in the fluid dose based on the at least one optical measurement of the reagent only in response to the at least one optical measurement being generated after a predetermined minimum time period has elapsed and prior to a predetermined maximum time period elapsing subsequent to the activating of the timer.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
68.
SYSTEM AND METHOD FOR AUTOMATED OPTICAL ANALYTE MEASUREMENTS VIA WEARABLE SMART DEVICES
Systems and methods for measuring an analyte include devices configured to perform an analyte testing operation. The devices include a wearable electronic device and a remote device operatively connected to each other and each having a processor, the processors cooperating with each other in the execution of program instructions configured to direct the devices in the performance of the analyte testing operation. The wearable electronic device includes a camera configured to generate a video stream and one or more images relating to a user removing a test strip from a vial, producing a bodily fluid sample, and applying the sample to a deposit site of the test strip where the sample undergoes changes in one or more optical properties, the image of which is analyzed to determine a level of the analyte. The wearable electronic device further includes a head-up display (HUD) for providing output messages to the user relating to the performance and status of the analyte testing operation.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
69.
ENHANCED METHOD FOR THE DETERMINATION OF AN ANALYTE CONCENTRATION IN BODILY FLUID
The present invention relates to an analytical method for determining a concentration of an analyte in a bodily fluid by using a mobile device having at least one camera, at least one lidar sensor, at least one processor, and at least one display, wherein the at least one camera and the at least one lidar sensor comprise an at least partially overlapping field of view, the method comprising the following steps: a) providing at least one object, the at least one object being selected from the list comprising: an optical test element having a reagent test region, a color reference card having a reagent test region, a color reference card adapted to be associated with an optical test element having a reagent test region; wherein the reagent test region is adapted for application of a sample of the bodily fluid, and wherein the reagent test region is adapted to undergo, at least partially, a color formation reaction when the sample of the bodily fluid is applied to the reagent test region; b1) prompting, by the display, a user to apply a drop of the bodily fluid to the reagent test region and/or prompting, by the display, a user to confirm application of a drop of the bodily fluid to the reagent test region; b2) prompting, by the display, the user to provide the at least one object within the at least partially overlapping field of view of the at least one camera and the at least one lidar sensor; c) generating, by the processor, a lidar measurement data set at least for the object by receiving output data from the at least one lidar sensor, the lidar measurement data set representing a three-dimensional structure of at least a part of the object; d) comparing, by the processor, the lidar measurement data set from step c) to a pre-generated lidar data set for the object, the pre-generated lidar data set representing a three-dimensional structure of the entire object, thereby obtaining an item of information on a degree of congruence of the lidar measurement data set and the pre-generated lidar data set; and e1) if the item of information from step d) indicates a degree of congruence equal to or above a pre-determined minimum degree of congruence: capturing, by the at least one camera, a measurement image of at least a part of the reagent test region having the sample of the bodily fluid applied thereto, and determining the concentration of the analyte in the bodily fluid based at least on the measurement image captured; or e2) if the item of information from step d) indicates a degree of congruence below a pre-determined minimum degree of congruence: - at least temporarily not allowing the capturing, by the at least one camera, of a measurement image of at least a part of the reagent test region having the sample of the bodily fluid applied thereto; and/or - indicating, by the display, a warning to the user; and/or - indicating, by the display, instractions to the user to take some appropriate action in order to capture, by the at least one camera, a measurement image of at least a part of the reagent test region having the sample of the bodily fluid applied thereto.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01S 17/88 - Lidar systems, specially adapted for specific applications
The present invention relates to an analyte sensor comprising a substrate, a first conductive material, a second conductive material, a first layer and a second layer, wherein the first and the second layer, in-dependently of one another have a varying thickness along the length of the substrate and/or are located on the substrate as at least two fields separate from one another. The present invention further-more relates to a method for manufacturing the analyte sensor and an analyte sensor system comprising the analyte sensor.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
The present invention relates to an analyte sensor comprising a substrate, at least one first electrode, at least one second electrode and at least one protective layer covering the at least one second electrode. The present invention further relates to a process for manufacturing the inventive analyte sensor as well as to an analyte sensor system comprising an analyte sensor according to the present invention and an electronics unit. The analyte sensor according to the present invention may mainly be used for conducting analyte measurements in a body fluid of a user.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
72.
METHODS AND DEVICES FOR CONTROLLING AUTO WHITE BALANCE SETTINGS OF A MOBILE DEVICE FOR A COLOR BASED MEASUREMENT USING A COLOR REFERENCE CARD
A method of controlling auto white balance settings of a mobile device with a camera and preset auto white balance modes for performing a color based measurement comprising the steps of capturing an image of at least part of one or more gray fields of a color reference card, determining for a region of interest within the image a number of gray fields for which the color information for a first and a second color shows overexposure as a first and second overexposure-number, respectively, the first color relating to a smaller wavelength than the second color, and re-capturing the image with a warmer white balance mode if the first overexposure number is greater than the second overexposure number or re-capturing the image with a cooler white balance mode if the first overexposure number is smaller than the second overexposure number.
G09G 5/02 - Control arrangements or circuits for visual indicators common to cathode-ray tube indicators and other visual indicators characterised by the way in which colour is displayed
G09G 3/20 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/29 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
The present invention relates to a manual insertion aid for inserting a cannula unit into a cannula holder. The manual insertion aid comprises a handle and two jaws projecting from the handle and forming a receiving opening that is configured for engaging with a cannula unit. In order to provide a simple and lightweight insertion aid, the minimum clearance between the two jaws is greater than or equal to 1.5 mm and smaller than or equal to 7 mm, and wherein the maximum projecting length of each of the two jaws from the handle is greater than or equal to 4 mm and smaller than or equal to 18 mm.
A device comprising a body part that is attachable to a body of a patient, wherein the body part comprises a receiving opening through which a functional element can be reversibly introduced into a body of a patient by means of an inserting device, like a needle, wherein the body part comprises a sealing member that is adapted to seal at least a part of the receiving opening after removal of the inserting device.
e.g.,e.g., a mobile device) may determine a first notification visibility level for the user health-related event based on a context. The user device may receive data associated with the user health-related event. The user device may determine an adherence level for the user health-related event based on the data associated with the user health-related event. The user device may determine a second notification visibility level for the user health-related event based on comparison of the adherence level to a plurality of predefined adherence thresholds. The user device may communicate, using the second notification visibility level, a notification associated with the user health-related event via the user device upon detection of a triggering event. The user device may group, based on the context, one or more user health-related events into a notification group.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G08B 21/24 - Reminder alarms, e.g. anti-loss alarms
G16H 10/65 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records stored on portable record carriers, e.g. on smartcards, RFID tags or CD
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
A device for transcutaneous insertion comprising a flexible insertion piece (1) for transcutaneous insertion, characterized in the flexible insertion piece (1) comprising a deformation measurement device for detecting one or more deformation signals, a transcutaneous insertion system, comprising such a device for transcutaneous insertion and a method of detecting deformation of at least a part of the insertion piece of a device for transcutaneous insertion.
An analyte sensor (110) for determining at least one analyte and a method (140) for producing an analyte sensor (110) are disclosed. The analyte sensor (110) comprises: - a substrate (112); - a working electrode (118) and a conductive layer (124) located on different sites on the substrate (112); - a silver comprising layer (126) partially covering the conductive layer (124); and - a protective layer (128), which • comprises at least one electrically conductive material; and • covers the silver comprising layer (126) apart from at least one at least one hole that provides access for at least one body fluid comprising the at least one analyte to the silver comprising layer (126). Although the analyte sensor (110) as disclosed herein has a reduced overall size, sufficient space is, nevertheless, provided for the silver comprising layer (126) coated by the protective layer (128) while, concurrently, further sufficient space remains which is neither coated by the silver comprising layer (126) nor by the protective layer (128).
The invention relates to a system, a sensor and a method for measuring an analyte concentration using an electrochemical analyte sensor, the analyte sensor comprising a first electrode and a second electrode, the first electrode being configured to react with the analyte for generating an electrical signal, wherein the method comprises: applying (201) a modulated voltage signal between the first electrode and the second electrode, determining (202) a current signal in response to the applied modulated voltage signal, determining (203) an electric potential working point of the analyte sensor based on the determined current signal, operating (204) the analyte sensor at the determined electric potential working point, and measuring (205) the analyte concentration based on the electrical signal generated by the first electrode.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/413 - Concentration cells using liquid electrolytes
G01N 27/48 - Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
The present invention relates to an analyte sensor comprising a substrate, at least one first electrode, at least one second electrode and at least one protective layer covering the at least one second electrode. The present invention further relates to a process for manufacturing the inventive analyte sensor as well as to an analyte sensor system comprising an analyte sensor according to the present invention and an electronics unit. The analyte sensor according to the present invention may mainly be used for conducting analyte measurements in a body fluid of a user.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
80.
ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR
An analyte sensor comprises a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which partially overlap with one another and have different compositions, i.e. silver percentages. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
81.
NON-INVASIVE DETERMINATION OF BLOOD GLUCOSE LEVELS
A method to determine a subject's blood glucose level non-invasively by analyzing an exhaled breath or another gaseous emanation from the subject, comprising non-invasively detecting an amount of at least one volatile organic marker in the subject's exhaled breath or the subject's other gaseous emanation as marker data and determining the subject's blood glucose level based on the marker data, wherein the volatile organic marker is selected from a group of markers for which the amount of the volatile organic marker is negatively correlated to the blood glucose level. The volatile organic marker is one of indole (C8H7N), a partly saturated derivative of indole, a fully saturated derivative of indole and a true fraction of indole.
An analyte sensor (110) for determining at least one analyte and a method (140) for producing an analyte sensor (110) are disclosed. The analyte sensor (110) comprises: - a substrate (112); - a working electrode (118) and a conductive layer (122, 124) located on different sites on the substrate (112); - a silver comprising layer (126) partially covering the conductive layer (124); and - a protective layer (128) covering - the silver comprising layer (126) fully apart from at least one area (130) accessible to at least one body fluid comprising the at least one analyte; and - a portion of the conductive layer (124). The analyte sensor (110) as proposed herein significantly reduces noise during measurements. The method (140) which can be performed in an easier manner compared to producing prior art analyte sensors allows considerably higher tolerances during the producing of the analyte sensor (110).
A method for determining a reliability of an analyte sensor (110) is proposed. The analyte sensor (110) is an in vivo sensor. The method comprises the steps: a) measuring at least one first temperature dependent signal; b) measuring at least one second temperature dependent signal which is different from the first temperature dependent signal and which is related to a current flow in the analyte sensor (110); c) correlating the first temperature dependent signal and the second temperature dependent signal for determining the reliability of the analyte sensor (110).
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/1495 - Calibrating or testing in vivo probes
84.
METHOD AND SYSTEM FOR AUTOMATED ACTIVITY RECOMMENDATION IN DIABETES TREATMENT PLANS
A method for generating activity recommendations in a diabetes treatment plan includes receiving physiological data, preferences, and suggested activities for a person with diabetes (PwD), generating physiological profiles for the PwD, providing the physiological profiles to a virtual physiological model, receiving projections from a virtual physiological model, generating weighted values based on the suggested activities and preference data, each weighted value corresponding to a likelihood of the PwD adhering to a suggested activity, ranking each activity based on the estimated change in the physiological characteristic of a projection associated with the activity relative to a baseline physiological projection and scaled by the weighted value corresponding to each activity, and generating an output including a predetermined number of suggested activities ordered based on the ranking of activities that provide a greatest change in the physiological characteristic given the likelihood of the PwD adhering to the suggested activities.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
The present invention relates to a medical device system comprising a body-wearable medical device, and a disposable container comprising a reservoir volume configured for storing a foodstuff or a drug and a tamper evident closure which seals an opening in the disposable container, wherein the opening provides access to the reservoir volume. To reduce the burden of the patient to compose the packages to be carried along by a patient when leaving home, the disposable container comprises a body-wearable medical device fastener configured for detachable fastening the disposable container to the body-wearable medical device and/or the body-wearable medical device comprises a disposable container fastener configured for detachable fastening the body-wearable medical device to the disposable container.
Method and means for postprandial blood glucose level prediction The invention relates to a method (100) for predicting blood glucose levels, in particular for postprandial blood glucose level prediction, the method being computer-implemented and comprising: receiving (101) a first medical data set of a patient covering a time range, said first medical data set comprising glucose data and further other medical data of said patient, extracting (102) a second medical data set from said first medical data set, wherein the second medical data set is a subset of the first medical data set and wherein the extracting comprises at least one of: identifying (103) duplicates in the first medical data set and removing identified duplicates, identifying (104) data values that lie above a predefined maximum threshold data value or identifying (105) data values that lie below a predefined minimum threshold data value and removing data associated to said identified data values, identifying (106) data values that differ from predetermined expected data values by more than a predetermined amount and removing data associated to said identified data values, identifying (107) incomplete data for which data values are missing and removing identified incomplete data, identifying (108) at least one predetermined time-dependent data pattern and removing data associated to said identified time-dependent data pattern, providing (109) the extracted second medical data set as input to a blood glucose level prediction model, and predicting (110) future blood glucose levels of the patient using the output of the blood glucose level prediction model based on the second medical data set.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
87.
METHOD FOR SCREENING A SUBJECT FOR THE RISK OF CHRONIC KIDNEY DISEASE, COMPUTER-IMPLEMENTED METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT
A method for screening a subject for the risk of chronic kidney disease (CKD) is provided, the method comprising: receiving marker data indicative for a plurality of marker parameters for a subject, such plurality of marker parameters indicating at least an age value, a time since diagnosis value indicative of a time since a diabetes diagnosis for the subject, a sample level of creatinine, an estimated glomerular filtration rate, a sample level of albumin, and a sample level of blood urea nitrogen; and determining a risk factor indicative of the risk of suffering CKD for the subject from the plurality of marker parameters. Further, a computer-implemented method for screening a subject for the risk of CKD is provided. Also, a system comprising a processor and a non-transitory memory storing a program causing the processor to perform the method for screening a subject for the risk of CKD is provided. In another aspect, a computer program product comprising instructions which, when the program is executed by a computer, cause the computer to carry out the method for screening a subject for the risk of CKD is provided.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
The invention relates to a method (100) for updating at least one medical practice software for displaying and analyzing blood glucose data on at least one computing device of a plurality of computing devices of a local network, the method comprising: determining (101), by a first computing device of said plurality of computing devices, what versions of the at least one medical software are installed on the computing devices of said plurality of computing devices; receiving (102), at a first computing device of said plurality of computing devices, at least one software patch, said software patch comprising at least one update for a version of the medical software installed on at least one computing device of said plurality of computing devices; identifying (103), by the first computing device, which of the at least one computing device of said plurality of computing devices has installed a version of the at least one software that requires an update comprised in said at least one software patch; transmitting (104), by the first computing device, a copy of the at least one software patch, to at least one computing device of said plurality of computing devices that has been identified as having installed a version of the at least one medical practice software that requires an update comprised in said at least one software patch; and installing (105) the at least one update from the software patch to update the medical practice software on at least one computing device identified by the first computing device.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
The present invention relates to a device for implantation into a mammalian host, said device comprising a) a dialysis tube with a lumen and a dialysis membrane enclosing said lumen, wherein i) the dialysis tube has an outer diameter of from 20 µm to 600 µm; and ii) the dialysis membrane has a molecular weight cutoff of from 25 kDa to 150 kDa and comprises at least one material selected from the group consisting of polyethersulfone, polyarylethersulfone, polyethylene, polytetrafluoroethylene, polyvinylidene fluoride, and polypropylene; and b) a therapeutic composition disposed within the lumen of the dialysis tube, wherein said therapeutic composition comprises a plurality of cells secreting a therapeutic compound and a matrix material embedding said cells secreting a therapeutic compound, wherein the matrix material is selected from alginate, collagen, fibrin, extracellular matrix material, synthetic hydrogel, and acrylate, in an embodiment the matrix material is alginate. The present invention further relates to a method of producing a device for implantation, a port system, and a cell secreting a therapeutic compound for use in treating disease by implantation of said cell in a device for implantation according to the present invention.
An insertion system (110) is disclosed. The insertion system (110) comprises a medical device (112) and an insertion device (113) for inserting the medical device (112) into a body tissue of a user, the insertion device (113) comprising: i) an insertion component (118) configured for inserting the medical device (112) into the body tissue; ϋ) an insertion component retractor (120); iii) a cap (122); iv) a guide sleeve (124) and an insertion sleeve (128) guided therein; v) a locking sleeve (126) positioned in the insertion sleeve (128); and vi) an elastic member (130) positioned between the locking sleeve (126) and the insertion component retractor (120); wherein, for inserting the medical device (112), the cap (122), the insertion component retractor (120), the locking sleeve (126) and the insertion sleeve (128) are movable relative to the guide sleeve (124) from a distal position to a proximal position, wherein the insertion device (113) is separable from the medical device (112), wherein the insertion system (110) is configured such that a separation of the insertion device (113) from the medical device (112) releases a movement of the locking sleeve (126) from its proximal position to a further proximal position.
Medical device efficiency detection methods and systems including a photoplethysmography (PPG) sensor device, a processor, a memory, and machine readable instructions that may cause the system to receive a notification at the PPG device from the medical device upon delivery of the therapy treatment, use the PPG device to search for a signal response of the user based on the notification within a period of time to generate a response signal indicative of therapy treatment delivery, and transmit an alert when the response signal is not generated in the period of time indicative of a failure to detect sufficient therapy treatment delivery. The instructions may cause the system to transmit an alert when signal measurements from the PPG device of an infusion site are not within a sufficient signal range to indicate the infusion site is insufficient for delivery of the therapy treatment by the medical device.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A user device (e.g., a mobile device) receives testing period data during a testing period. The user device determines that a portion of the data is missing based on an analysis of the received testing period data. The analysis of the received data includes an analysis of one or more blood glucose levels and an analysis of the dietary intake data, the medication data, and the activity data. The user device imputes the missing portion of the data with substitute data determined using predictive learning. The user device calculates a confidence level associated with the substitute data. The user device identifies, using the substitute data, a progression or a regression in a diabetic condition associated with the user.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
94.
METHOD FOR PREPARING A COUNTER/REFERENCE ELECTRODE
The present invention generally relates to a method for the preparation of an electrode and to an analyte sensor comprising the electrode as well as to the use of the analyte sensor for detecting at least one analyte in a sample. In particular, the invention relates to a method for the preparation of an electrode, the method comprising a partial reduction of Ag+ cations present in the electrode material.
A method for the preparation of a working electrode comprises application of a sensing material in several steps. Further, an analyte sensor comprises the working electrode and is used for detecting at least one analyte in a sample.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
B05D 1/26 - Processes for applying liquids or other fluent materials performed by applying the liquid or other fluent material from an outlet device in contact with, or almost in contact with, the surface
B05D 5/02 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a matt or rough surface
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
The present invention relates to a method for the preparation of a working electrode, the method comprising application of a sensing material in several steps. Further, the present invention relates to an analyte sensor comprising the working electrode as well as to the use of the analyte sensor for detecting at least one analyte in a sample.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
The present invention generally relates to a flux-limiting polymer membrane for an analyte sensor and to an analyte sensor comprising a flux-limiting polymer membrane.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
98.
METHOD FOR PRODUCING AN ANALYTE SENSOR, AN ANALYTE SENSOR, AND A USE THEREOF
A method (110) for producing an analyte sensor (112), an analyte sensor (112) obtainable by this method (110), and a use of the analyte sensor (112) are disclosed. The method (110) comprising the steps of: a) providing a first substrate (114) having o a first side (116), and o a second side (118), wherein the second side (118) has a first layer (120) comprising a first conductive material (122); b) providing a second substrate (124) having o a first side (126), wherein the first side (126) has a second layer (130) comprising a second conductive material (132), and o a second side (128), wherein second side (128) has a third layer (134) comprising a third conductive material (136); c) applying a layer (138) of an conductive preparation (140) onto at least one of the first side (116) of the first substrate (114) or the third layer (134) or a portion thereof, wherein the conductive preparation (140) comprises o a plurality of conductive particles, and o at least one polymeric binder; d) laminating the first side (116) of the first substrate (114) with the second side (128) of the second substrate (124); and e) obtaining the analyte sensor (112). The method (110) is a cost-efficient process which allows producing the analyte sensor (112) in a reliable and fast fashion, whereby an individual tailoring of the analyte sensor (112) is, concurrently, possible.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/30 - Electrodes, e.g. test electrodesHalf-cells
P36339 - 35 - Method for manufacturing at least one electrode of an analyte sensor Abstract A method for manufacturing at least one electrode (110) of an analyte sensor (112) is dis-5 closed. The method comprises the following steps: a) providing (116) a stencil (118), wherein the stencil (118) comprises a first stencil side (120), a second stencil side (122) and at least one through hole (124) reaching from the first stencil side (120) to the second stencil side (122), wherein at least one of the first stencil side (120) and the second stencil side (122) has first wetta-10 bility properties; b) providing (126) a substrate (128), wherein the substrate (128) comprises a first side (130) and a second side (134); c) applying (136) the stencil (118) to the first side (130) of the substrate (128); d) applying (138) a low viscosity composition (140) into the through hole (124) of 15 the stencil (118), wherein the low viscosity composition (140) has second wetta- bility properties opposing to the first wettability properties of the at least one of the first stencil side (120) and the second stencil side (122); e) drying (141) the low viscosity composition (140); f) obtaining (142) the at least one electrode (110). 20 (Figure 2A)
A61B 5/1477 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means non-invasive
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
H05K 3/12 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using printing techniques to apply the conductive material
100.
ANALYTE SENSOR SYSTEM AND A METHOD FOR ITS PRODUCING
An analyte sensor system (110) and a method (160) for producing an analyte sensor system (110) are disclosed. Herein, the analyte sensor system (110) comprises: - an analyte sensor having o a first contact pad, and o a second contact pad; - a circuit carrier having o a first contact area, and o a second contact area, wherein the second contact area comprises at least two individual electrically conductive surfaces; and - a connecting element electrically connecting the second contact pad of the analyte sensor with each of the at least two individual electrically conductive surfaces of the second contact area of the circuit carrier. The analyte sensor system (110) as proposed herein allows a reliable and persistent electrical contact between the analyte sensor (112) and the circuit carrier (114) which minimizes a risk of short circuits.
patents
