Polypid Ltd.

Israel

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2025 2
2024 3
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2022 3
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IPC Class
A61K 9/00 - Medicinal preparations characterised by special physical form 15
A61K 31/65 - Tetracyclines 13
A61L 27/54 - Biologically active materials, e.g. therapeutic substances 9
A61K 9/14 - Particulate form, e.g. powders 7
A61K 9/16 - AgglomeratesGranulatesMicrobeadlets 7
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 9
10 - Medical apparatus and instruments 9
Status
Pending 5
Registered / In Force 33

1.

POLYPID

      
Application Number 1892428
Status Registered
Filing Date 2025-10-15
Registration Date 2025-10-15
Owner PolyPid Ltd (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, drug delivery formulations for medical use. Drug delivery systems for medical use.

2.

POLYPID

      
Application Number 244451400
Status Pending
Filing Date 2025-10-15
Owner PolyPid Ltd (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

(1) Drug carriers for medical use, drug delivery formulations for medical use. (2) Drug delivery systems for medical use.

3.

BACFENSSI

      
Application Number 235064200
Status Pending
Filing Date 2024-09-03
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

(1) Drug carriers for medical use, namely, polymer-lipid matrix formulation for localized drug delivery; drug delivery formulations for medical use, namely, drug delivery agents in the form of polymer-lipid matrix for sustained delivery of drugs; drug delivery formulations for medical use, namely, drug delivery formulations in the form of powders and pastes that provide sustained release of a wide variety of pharmaceutically active agents; antibiotic delivery formulations for medical use, comprising polymer-lipid based matrix formulations for the continuous release of antibiotic drugs for medical use, namely for the prevention and treatment of infections associated with surgical procedures; drug delivery formulations for medical use, namely, drug delivery agents comprised of polymeric based particles coated with polymer-lipid matrix for sustained delivery of antibiotics; drug delivery formulations for medical use, namely, drug delivery agents comprised of polymeric based particles impregnated with polymer-lipid matrix for sustained delivery of antibiotics; drug delivery formulations for medical use, namely, drug delivery agents being mineral based particles coated with polymer-lipid matrix for sustained delivery of antibiotics; drug delivery formulations for medical use, namely, drug delivery agents being mineral based particles impregnated with polymer-lipid matrix for sustained delivery of antibiotics. (2) Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, bone screws, surgical staples, medical guidewires and surgical k-wires, surgical pins, surgical sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained drug delivery; drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, bone screws, surgical staples, medical guidewires and surgical k-wires, surgical pins, surgical sponges, metal and polymeric implants, all impregnated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, bone screws, surgical staples, medical guidewires and surgical k-wires, surgical pins, surgical sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained antibiotic drug delivery.

4.

COMPOSITIONS AND METHODS FOR THE TREATMENT AND PROPHYLAXIS OF SURGICAL SITE INFECTIONS

      
Application Number 18626776
Status Pending
Filing Date 2024-04-04
First Publication Date 2024-07-25
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.

IPC Classes  ?

  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
  • A61K 31/65 - Tetracyclines
  • A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

5.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF SOLID TUMORS

      
Application Number 18266776
Status Pending
Filing Date 2021-12-21
First Publication Date 2024-02-15
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for treating solid tumors, reducing local tumor recurrence and tumor metastatic spreading, by administering directly into the tumor or to the tumor resection cavity a pharmaceutical composition comprising a particulate biodegradable substrate coated with a polymer-lipid based matrix which provide local sustained release of a taxane chemotherapeutic drug. The present invention further provides methods for treating chemotherapy resistant tumors.

IPC Classes  ?

  • A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
  • A61P 35/00 - Antineoplastic agents

6.

BACZENSSI

      
Application Number 018944153
Status Registered
Filing Date 2023-10-31
Registration Date 2024-04-24
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, namely, antibiotic polymer-lipid matrix formulations for the prevention and treatment of infections associated with surgical procedures; drug delivery formulations for medical use. Drug delivery systems for medical use.

7.

Compositions and methods for the treatment and prophylaxis of surgical site infections

      
Application Number 17819008
Grant Number 11975101
Status In Force
Filing Date 2022-08-11
First Publication Date 2022-12-15
Grant Date 2024-05-07
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.

IPC Classes  ?

  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
  • A61K 31/65 - Tetracyclines
  • A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

8.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF SOLID TUMORS

      
Document Number 03197114
Status Pending
Filing Date 2021-12-21
Open to Public Date 2022-06-30
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for treating solid tumors, reducing local tumor recurrence and tumor metastatic spreading, by administering directly into the tumor or to the tumor resection cavity a pharmaceutical composition comprising a particulate biodegradable substrate coated with a polymer-lipid based matrix which provide local sustained release of a taxane chemotherapeutic drug. The present invention further provides methods for treating chemotherapy resistant tumors.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
  • A61P 35/00 - Antineoplastic agents
  • A61P 35/04 - Antineoplastic agents specific for metastasis

9.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF SOLID TUMORS

      
Application Number IB2021062116
Publication Number 2022/137126
Status In Force
Filing Date 2021-12-21
Publication Date 2022-06-30
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for treating solid tumors, reducing local tumor recurrence and tumor metastatic spreading, by administering directly into the tumor or to the tumor resection cavity a pharmaceutical composition comprising a particulate biodegradable substrate coated with a polymer-lipid based matrix which provide local sustained release of a taxane chemotherapeutic drug. The present invention further provides methods for treating chemotherapy resistant tumors.

IPC Classes  ?

  • A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61P 35/00 - Antineoplastic agents
  • A61P 35/04 - Antineoplastic agents specific for metastasis

10.

BACFENSSI

      
Application Number 1612805
Status Registered
Filing Date 2021-07-08
Registration Date 2021-07-08
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, drug delivery formulations for medical use. Drug delivery systems for medical use.

11.

OPZIFEND

      
Application Number 1612811
Status Registered
Filing Date 2021-07-08
Registration Date 2021-07-08
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, drug delivery formulations for medical use. Drug delivery systems for medical use.

12.

BACFENSSI

      
Serial Number 79320158
Status Registered
Filing Date 2021-07-08
Registration Date 2022-08-30
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, namely, polymer-lipid matrix formulation for localized drug delivery; drug delivery formulations for medical use, namely, drug delivery agents in the form of polymer-lipid matrix for sustained drug delivery; drug delivery formulations for medical use, namely, drug delivery formulations being drug delivery agents in the form of powders and pastes that provide sustained release of the active ingredients for a wide variety of pharmaceuticals; antibiotic delivery systems comprising polymer-lipid based matrix formulation for the continuous release of antibiotic drugs for medical use, namely for the prevention and treatment of infections associated with surgical procedures; drug delivery systems for medical use, namely, drug delivery agents being polymeric based particles coated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being polymeric based particles impregnated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being mineral based particles coated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being mineral based particles impregnated with polymer-lipid matrix for sustained antibiotic drug delivery Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained drug delivery; Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all impregnated with polymer-lipid matrix for sustained antibiotic drug delivery; Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained antibiotic drug delivery

13.

OPZIFEND

      
Serial Number 79320159
Status Registered
Filing Date 2021-07-08
Registration Date 2022-08-30
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, namely, polymer-lipid matrix formulation for localized drug delivery; drug delivery formulations for medical use, namely, drug delivery agents in the form of polymer-lipid matrix for sustained drug delivery; drug delivery formulations for medical use, namely, drug delivery formulations being drug delivery agents in the form of powders and pastes that provide sustained release of the active ingredients for a wide variety of pharmaceuticals; antibiotic delivery systems comprising polymer-lipid based matrix formulation for the continuous release of antibiotic drugs for medical use, namely for the prevention and treatment of infections associated with surgical procedures; drug delivery systems for medical use, namely, drug delivery agents being polymeric based particles coated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being polymeric based particles impregnated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being mineral based particles coated with polymer-lipid matrix for sustained antibiotic drug delivery; drug delivery systems for medical use, namely, drug delivery agents being mineral based particles impregnated with polymer-lipid matrix for sustained antibiotic drug delivery Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained drug delivery; Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all impregnated with polymer-lipid matrix for sustained antibiotic drug delivery; Drug delivery systems for medical use, namely, surgical instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained antibiotic drug delivery

14.

POLYPID

      
Serial Number 90584390
Status Registered
Filing Date 2021-03-17
Registration Date 2022-07-12
Owner PolyPid Ltd. (Israel)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

Drug carriers for medical use, namely, polymer-lipid matrix for localized drug delivery; drug delivery agents in the form of polymer-lipid matrix for sustained delivery; drug delivery formulations for medical use, namely, drug delivery formulations being drug delivery agents in the form of powders and pastes that provide sustained release of the active ingredients for a wide variety of pharmaceuticals; Drug delivery systems for medical use, namely, surgical, biomedical, orthopaedic and dental materials being drug delivery agents in the form of allogeneic, xenogeneic and synthetic bone filler particles coated with polymer-lipid matrix for sustained drug delivery release of the active ingredients for a wide variety of pharmaceuticals Drug delivery systems for medical use, namely, surgical, biomedical, orthopaedic and dental instruments and materials being sutures, orthopedic and dental nails, screws, staples, wires, pins, sponges, metal and polymeric implants, all coated with polymer-lipid matrix for sustained drug delivery

15.

Compositions and methods for the treatment and prophylaxis of surgical site infections

      
Application Number 16790009
Grant Number 11471414
Status In Force
Filing Date 2020-02-13
First Publication Date 2020-08-27
Grant Date 2022-10-18
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.

IPC Classes  ?

  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 31/65 - Tetracyclines
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
  • A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin

16.

Sustained-release drug carrier composition

      
Application Number 16122986
Grant Number 10682412
Status In Force
Filing Date 2018-09-06
First Publication Date 2019-03-07
Grant Date 2020-06-16
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/58 - Materials at least partially resorbable by the body
  • A61K 31/65 - Tetracyclines
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 31/06 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
  • A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
  • A61L 31/10 - Macromolecular materials

17.

Methods for the treatment of peri-implantitis

      
Application Number 15513163
Grant Number 10758639
Status In Force
Filing Date 2015-09-27
First Publication Date 2017-08-31
Grant Date 2020-09-01
Owner Polypid Ltd. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.

IPC Classes  ?

  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61K 6/58 - Preparations specially adapted for dental root treatment specially adapted for dental implants
  • A61K 31/65 - Tetracyclines
  • A61L 27/34 - Macromolecular materials
  • A61K 33/06 - Aluminium, calcium or magnesiumCompounds thereof
  • A61K 6/831 - Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
  • A61K 6/849 - Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
  • A61K 6/864 - Phosphate cements
  • A61K 6/891 - Compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 27/58 - Materials at least partially resorbable by the body

18.

Sustained-release drug carrier composition

      
Application Number 15244048
Grant Number 10105443
Status In Force
Filing Date 2016-08-23
First Publication Date 2016-12-08
Grant Date 2018-10-23
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/22 - Sustained or differential release type
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61P 31/04 - Antibacterial agents
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 27/58 - Materials at least partially resorbable by the body
  • A61L 31/06 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
  • A61K 31/65 - Tetracyclines
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
  • A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
  • A61L 31/10 - Macromolecular materials

19.

METHODS FOR THE TREATMENT OF PERI-IMPLANTITIS

      
Document Number 02961998
Status In Force
Filing Date 2015-09-27
Open to Public Date 2016-04-07
Grant Date 2022-07-26
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
  • A61K 33/42 - PhosphorusCompounds thereof
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

20.

COMPOSITIONS AND METHODS FOR THE TREATMENT AND PROPHYLAXIS OF SURGICAL SITE INFECTIONS

      
Application Number IB2015057409
Publication Number 2016/051321
Status In Force
Filing Date 2015-09-27
Publication Date 2016-04-07
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.

IPC Classes  ?

21.

METHODS FOR THE TREATMENT OF PERI-IMPLANTITIS

      
Application Number IB2015057410
Publication Number 2016/051322
Status In Force
Filing Date 2015-09-27
Publication Date 2016-04-07
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.

IPC Classes  ?

  • A61K 6/06 - Use of inorganic cements
  • A61K 9/52 - Sustained or differential release type
  • A61K 31/65 - Tetracyclines
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

22.

COMPOSITIONS AND METHODS FOR THE TREATMENT AND PROPHYLAXIS OF SURGICAL SITE INFECTIONS

      
Document Number 02963370
Status In Force
Filing Date 2015-09-27
Open to Public Date 2016-04-07
Grant Date 2023-04-25
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.

IPC Classes  ?

  • A61K 31/65 - Tetracyclines
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
  • A61P 31/02 - Local antiseptics
  • A61P 31/04 - Antibacterial agents
  • A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

23.

Compositions and methods for the treatment of bone voids and open fractures

      
Application Number 14418138
Grant Number 09173976
Status In Force
Filing Date 2013-08-01
First Publication Date 2015-07-23
Grant Date 2015-11-03
Owner Polypid Ltd. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone void or bone defect site a composition comprising a matrix which provides local prolonged release of at least one antibiotic agent at the bone void site.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61K 31/65 - Tetracyclines
  • A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
  • A61P 31/10 - Antimycotics
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61P 35/00 - Antineoplastic agents
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61L 27/34 - Macromolecular materials
  • A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof

24.

Sustained-release drug carrier composition

      
Application Number 14623528
Grant Number 10463617
Status In Force
Filing Date 2015-02-17
First Publication Date 2015-06-25
Grant Date 2019-11-05
Owner PolyPid Ltd. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61L 27/34 - Macromolecular materials
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61K 31/65 - Tetracyclines
  • A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
  • A61L 31/10 - Macromolecular materials
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances

25.

Sustained-release drug carrier composition

      
Application Number 14523894
Grant Number 09421271
Status In Force
Filing Date 2014-10-26
First Publication Date 2015-02-19
Grant Date 2016-08-23
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61F 2/28 - Bones
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 27/58 - Materials at least partially resorbable by the body
  • A61L 31/06 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
  • A61K 31/65 - Tetracyclines
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
  • A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
  • A61L 31/10 - Macromolecular materials

26.

Sustained-release nucleic acid matrix compositions

      
Application Number 14450310
Grant Number 09616032
Status In Force
Filing Date 2014-08-04
First Publication Date 2014-11-13
Grant Date 2017-04-11
Owner Polypid Ltd. (Israel)
Inventor
  • Emanuel, Noam
  • Rosenfeld, Yosef

Abstract

There are provided compositions for extended release of a nucleic acid agent, comprising a lipid-saturated matrix formed with a biodegradable polymer. Also provided are methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
  • A61K 9/107 - Emulsions
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy

27.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF BONE VOIDS AND OPEN FRACTURES

      
Document Number 02880130
Status In Force
Filing Date 2013-08-01
Open to Public Date 2014-02-06
Grant Date 2019-09-24
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone void or bone defect site a composition comprising a matrix which provides local prolonged release of at least one antibiotic agent at the bone void site.

IPC Classes  ?

  • A61F 2/46 - Special tools for implanting artificial joints
  • A61L 27/14 - Macromolecular materials

28.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF BONE VOIDS AND OPEN FRACTURES

      
Application Number IL2013050657
Publication Number 2014/020610
Status In Force
Filing Date 2013-08-01
Publication Date 2014-02-06
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone void or bone defect site a composition comprising a matrix which provides local prolonged release of at least one antibiotic agent at the bone void site.

IPC Classes  ?

  • A61F 2/28 - Bones
  • A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
  • A61K 33/06 - Aluminium, calcium or magnesiumCompounds thereof
  • A61P 31/04 - Antibacterial agents

29.

MATRIX COMPOSITIONS FOR CONTROLLED RELEASE OF PEPTIDE AND POLYPEPTIDE MOLECULES

      
Application Number IL2012050278
Publication Number 2013/014677
Status In Force
Filing Date 2012-07-26
Publication Date 2013-01-31
Owner POLYPID LTD. (Israel)
Inventor Emanuel, Noam

Abstract

The present invention provides compositions for controlled release of a peptidic molecule comprising a lipid-saturated matrix comprising a biocompatible polymer and a peptidic molecule associated with PEG. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the peptidic molecule.

IPC Classes  ?

30.

Sustained-release nucleic acid matrix compositions

      
Application Number 13574040
Grant Number 08795726
Status In Force
Filing Date 2011-01-18
First Publication Date 2012-11-22
Grant Date 2014-08-05
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Rosenfeld, Yosef

Abstract

The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.

IPC Classes  ?

  • A61K 9/26 - Discrete particles in supporting matrix

31.

Sustained-release drug carrier composition

      
Application Number 13383893
Grant Number 08992979
Status In Force
Filing Date 2010-07-14
First Publication Date 2012-05-10
Grant Date 2015-03-31
Owner Polypid Ltd. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract

The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61P 35/00 - Antineoplastic agents
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 31/04 - Antibacterial agents
  • A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
  • A61P 31/10 - Antimycotics
  • A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
  • A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
  • A61L 27/34 - Macromolecular materials
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 31/10 - Macromolecular materials
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances

32.

SUSTAINED-RELEASE NUCLEIC ACID MATRIX COMPOSITIONS

      
Document Number 02783001
Status In Force
Filing Date 2011-01-18
Open to Public Date 2011-07-28
Grant Date 2017-12-12
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Rosenfeld, Yosef

Abstract

The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.

IPC Classes  ?

  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy

33.

SUSTAINED-RELEASE NUCLEIC ACID MATRIX COMPOSITIONS

      
Application Number IL2011000054
Publication Number 2011/089595
Status In Force
Filing Date 2011-01-18
Publication Date 2011-07-28
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Rosenfeld, Yosef

Abstract

The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61F 2/02 - Prostheses implantable into the body

34.

Sustained-release drug carrier composition

      
Application Number 13003955
Grant Number 08877242
Status In Force
Filing Date 2009-07-14
First Publication Date 2011-05-19
Grant Date 2014-11-04
Owner Polypid Ltd. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61L 27/58 - Materials at least partially resorbable by the body
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61L 31/06 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

35.

SUSTAINED-RELEASE DRUG CARRIER COMPOSITION

      
Application Number IL2010000563
Publication Number 2011/007353
Status In Force
Filing Date 2010-07-14
Publication Date 2011-01-20
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract

The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block- co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

36.

LIPID-BASED SUSTAINED-RELEASE DRUG CARRIER MATRIX

      
Document Number 02767973
Status In Force
Filing Date 2010-07-14
Open to Public Date 2011-01-20
Grant Date 2019-06-18
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract

The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block- co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61L 31/16 - Biologically active materials, e.g. therapeutic substances

37.

SUSTAINED-RELEASE DRUG CARRIER COMPOSITION

      
Document Number 02730340
Status In Force
Filing Date 2009-07-14
Open to Public Date 2010-01-21
Grant Date 2017-02-07
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract


The present invention provides compositions for extended release of an active
ingredient, comprising a lipid-saturated
matrix formed from a biodegradable polymer. The present invention also
provides methods of producing the matrix compositions
and methods for using the matrix compositions to provide controlled release of
an active ingredient in the body of a subject
in need thereof.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/65 - Tetracyclines
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61L 27/28 - Materials for coating prostheses
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
  • A61P 19/00 - Drugs for skeletal disorders
  • A61P 31/04 - Antibacterial agents
  • C08J 3/215 - Compounding polymers with additives, e.g. colouring in the presence of a liquid phase the polymer being premixed with a liquid phase at least one additive being also premixed with a liquid phase
  • C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
  • C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable

38.

SUSTAINED-RELEASE DRUG CARRIER COMPOSITION

      
Application Number IL2009000701
Publication Number 2010/007623
Status In Force
Filing Date 2009-07-14
Publication Date 2010-01-21
Owner POLYPID LTD. (Israel)
Inventor
  • Emanuel, Noam
  • Neuman, Moshe
  • Barak, Shlomo

Abstract

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

IPC Classes  ?

  • A61F 13/00 - Bandages or dressingsAbsorbent pads